Microneedle sheet with aroma and method for manufacturing same

Abstract

[Problem] To provide a microneedle sheet with aroma capable of continuously releasing fragrance. [Solution] A microneedle sheet (1) with aroma comprises: an adhesive sheet (2) including a base material layer (20) and an adhesive layer (21); and a needle sheet (3) including fine protrusions (30) with an effective skin-beautifying component. The adhesive sheet (2) includes a fragrance region (A1) to which an aroma component is attached, and a functional region (A2) to which the needle sheet is pasted.

Description

Fragranced Micro-needle Sheet and Method for Producing the Same

[0001] The present invention relates to a micro-needle sheet having an aroma and a method for producing the same.

[0002] JP 2022-74152 A (Patent Document 1) discloses a water-soluble cosmetic sheet to which a fragrance can be added as a raw material.

[0003] JP 2022-74152 A

[0004] However, even if a fragrance is added to a raw material of a cosmetic such as a micro-needle sheet, it may volatilize during the manufacturing process, making it difficult to impart a scent.

[0005] The present invention has been made to solve the above problems, and an object thereof is to provide a fragranced micro-needle sheet capable of continuously emitting an aroma.

[0006] The fragranced micro-needle sheet according to one aspect of the present invention includes an adhesive sheet including a base material layer and an adhesive layer, and a needle sheet including fine protrusions containing an effective skin-beautifying component. The adhesive sheet includes an aromatic region to which a fragrance component is attached and a functional region to which the needle sheet is attached.

[0007] Preferably, the adhesive sheet and the needle sheet do not contain a fragrance.

[0008] Preferably, the fragrance component includes one or more fragrance components selected from the group consisting of linalool, α-pinene, limonene, terpinene-4-ol, α-santalol, geraniol, furanoeudesma 1,3-diene, linalyl acetate, isobutyl angelate, patchouli alcohol, benzyl acetate, carotol, α-himachalene, estragole (methyl chavicol), sabinene, and β-phenethyl alcohol.

[0009] Preferably, it further includes a protection plate for protecting the fine protrusions at a position facing one surface of the needle sheet.

[0010] A method for manufacturing a scented microneedle sheet according to one aspect of the present invention comprises the steps of: preparing a mold having fine recesses; filling the mold with raw materials for the needle sheet; drying the mold filled with raw materials; processing the dried needle sheet into a desired shape; attaching an adhesive sheet to the needle sheet after the processing step; processing the adhesive sheet into a desired shape to obtain an untreated microneedle sheet; and attaching fragrance components of a fragrance to at least the adhesive sheet of the untreated microneedle sheet.

[0011] Another aspect of the present invention relates to a method for manufacturing a scented microneedle sheet, comprising the steps of: preparing an adhesive sheet; attaching fragrance components of a fragrance to the adhesive sheet; preparing a mold having fine recesses; filling the mold with raw materials for the needle sheet; drying the mold filled with raw materials; processing the dried needle sheet into a desired shape; attaching an adhesive sheet with fragrance components attached to the processed needle sheet; and processing the adhesive sheet into a desired shape.

[0012] Preferably, the step of attaching the fragrance components of the fragrance is to hold the fragrance components in a housing filled with the fragrance components for a certain period of time, thereby attaching the fragrance components to at least the adhesive sheet.

[0013] Preferably, the fragrance contains fragrance components that adhere to the adhesive sheet.

[0014] Preferably, the fragrance includes at least one fragrance selected from the group consisting of lavender, geranium, rosemary, sweet orange, sweet marjoram, grapefruit, sandalwood, bergamot, lemon, frankincense, ylang-ylang, Roman chamomile, clary sage, juniper berry, neroli, rose, carrot seed, cypress, cedarwood, jasmine, basil, patchouli, palmarosa, petitgrain, myrrh, and rosewood.

[0015] The scented microneedle sheet of the present invention can continuously emit fragrance.

[0016] This figure shows a scented microneedle sheet according to one embodiment of the present invention, where (a) is a plan view and (b) is an explanatory diagram showing a cross-section. This is a flowchart showing a method for manufacturing a scented microneedle sheet according to one embodiment of the present invention. This is a flowchart showing a method for manufacturing a scented microneedle sheet according to a modified example of one embodiment of the present invention. This graph evaluates the psychological state before and after using the microneedle sheet, where (a) shows a comparative example and (b) shows Example 1. This graph shows the evaluation results of the persistence of the fragrance components of the scented microneedle sheet, where (a) shows Example 2 and (b) shows Example 3.

[0017] Embodiments of the present invention will be described in detail with reference to the drawings. In the drawings, the same or corresponding parts are denoted by the same reference numerals, and their descriptions will not be repeated.

[0018] <About the structure> Referring to Figure 1, the scented microneedle sheet (hereinafter also referred to as "microneedle sheet") 1 according to this embodiment will be described. The scented microneedle sheet 1 comprises an adhesive sheet 2 and a needle sheet 3 including fine protrusions 30 containing effective skin-beautifying ingredients. The adhesive sheet 2 includes a fragrance region A1 to which fragrance components are attached and a functional region A2 to which the needle sheet 3 is attached.

[0019] Microneedle Sheet 1 is a skincare item that allows effective skin-beautifying ingredients such as hyaluronic acid to penetrate deep into the skin by solidifying them into a needle-like shape and adhering closely to the skin. Microneedle Sheet 1 is used by applying it to the skin for several hours, for example, overnight (approximately 5 to 8 hours). Depending on the effective skin-beautifying ingredients it contains, Microneedle Sheet 1 can produce various effects, such as moisturizing effect, blood circulation promotion effect, improvement of dark circles and dullness, improvement of wrinkles and sagging, tone-up effect, and whitening effect.

[0020] The adhesive sheet 2 includes a base layer 20 and an adhesive layer 21. The shape of the adhesive sheet 2 can be appropriately designed to suit the desired shape. For example, it may be shaped to follow the contours of the eye bags (tear troughs), cover blemishes, follow the contours of the mouth, follow the contours of the nasolabial folds, cover the area between the eyebrows, etc., depending on the area of ​​concern, or it may be shaped geometrically, such as a circle or a polygon. This allows the user to locally apply effective skin-beautifying ingredients to the areas where they wish to improve their skin.

[0021] The base layer 20 is a film-like base material that facilitates the user's handling of the adhesive layer 2. The material of the base layer 20 is preferably a film, nonwoven fabric, or woven fabric, and the material of the base layer 20 is appropriately selected from resins or fibers such as urethane, olefin, polyvinyl chloride, cotton, rayon, and cellulose. This allows it to easily conform to the movement of the skin and the shape of the area.

[0022] The adhesive layer 21 maintains the needle sheet 3 in close contact with the skin for several hours. The material of the adhesive layer 21 is typically an acrylic adhesive, but can be selected from, for example, acrylic adhesives, urethane adhesives, silicone adhesives, or rubber adhesives. This makes it less likely to cause skin irritation even when applied to the skin for several hours.

[0023] The thickness of the adhesive layer 21 is, for example, 10 to 1000 μm, preferably 15 to 100 μm. By making the thickness 15 μm or more, a sufficient amount of fragrance components can be attached to the adhesive layer 21.

[0024] The needle sheet 3 includes one surface 31 on which the fine protrusions 30 are arranged, and the other surface 32 which is attached to the adhesive layer 21. The size of the needle sheet 3 in this embodiment is slightly smaller than the outer dimensions of the adhesive sheet 2, and it is positioned so as to be bordered by the adhesive sheet 2 in a plan view.

[0025] The fine protrusions 30 are arranged in large numbers on one surface 31 of the needle sheet and contain a water-soluble polymer, which is the main component, and an effective skin-beautifying ingredient. The effective skin-beautifying ingredient is at least one component selected from the group consisting of, for example, hyaluronic acid, niacinamide, retinol, retinal, tranexamic acid, bakuchiol, glycyrrhizic acid, glutathione, collagen, centella asiatica extract, placenta extract, ceramide, retinoic acid tocopheryl, tocopherol, stem cell culture fluid, vitamin C derivatives, and plant and animal extracts. The plant and animal extracts referred to here are not particularly limited as long as they are commonly used in pharmaceuticals, cosmetics, etc. Vitamin C derivatives include, for example, sodium ascorbate and magnesium ascorbyl phosphate.

[0026] The shape of the micro-protrusions 30 can be approximately needle-shaped, and can take shapes such as cone, frustocone, pyramidal, frustocone, conical (volcanic), or cylindrical. Here, "approximately needle-shaped" is preferably a shape that tapers towards the tip. This makes it easier for the protrusions to penetrate the stratum corneum. In this embodiment, the micro-protrusions 30 are arranged as a single component on one surface of the needle sheet 3, but they may be arranged as separate components.

[0027] The height of the micro-protrusions 30 is, for example, 20 μm to 1000 μm, preferably 50 μm to 200 μm. This allows the micro-protrusions 30 to penetrate between the stratum corneum of the skin, enabling effective skin-beautifying ingredients to penetrate into the epidermis.

[0028] In this embodiment, the needle sheet 3 has been described as a single sheet including the micro-protrusions 30, but it may also be composed of only a plurality of micro-protrusions 30. In this case, the other side 32 of the micro-protrusions 30 is attached to the adhesive layer 21.

[0029] Furthermore, the microneedle sheet 1 of this embodiment further includes a protective plate 4 that protects the fine protrusions 30 at a position facing one surface 31 of the needle sheet 3. The protective plate 4 of this embodiment has substantially the same shape as the adhesive sheet 2, and the surface facing one surface 31 of the needle sheet 3 is provided with a recess capable of receiving the fine protrusions 30 of the needle sheet 3. In other words, the protective plate 4 can protect the fine protrusions 30 while keeping the adhesive sheet 2 hygienic. Note that the protective plate 4 does not have to be substantially the same shape. For example, the protective plate 4 may be slightly larger than the adhesive sheet 2, or multiple adhesive sheets 2 may be arranged on a single protective plate.

[0030] The thickness of the protective plate 4 is preferably 500 μm to 1500 μm, from the viewpoint of facilitating the peeling of the adhesive sheet 2. If the thickness of the protective plate 4 is less than 500 μm, the adhesive sheet 2 may be difficult to peel off and may be difficult to handle.

[0031] The protective plate 4 is typically made of resin, but it is sufficient if it can suitably peel off the adhesive sheet 2 and the needle sheet 3. The material of the protective plate 4 can be selected from a variety of materials, such as acrylic resin, polyethylene resin, polypropylene resin, vinyl chloride resin, ABS resin, and silicone resin. The protective plate 4 may also be composed of multiple materials, such as a paper or cloth plate with resin coated on one side.

[0032] <Regarding fragrance components> The adhesive sheet 2 of the scented microneedle sheet 1 according to this embodiment includes a fragrance region A1 to which fragrance components are attached and a functional region A2 to which the needle sheet 3 is attached.

[0033] Fragrance components are volatile and gaseous components found in fragrances such as aroma oils, essential oils, and perfumes. While fragrance components can include a variety of components, it is preferable to select them appropriately according to the desired effect, such as relaxation or ease of falling asleep. Fragrance components can include, for example, one or more components selected from the group consisting of linalool, α-pinene, limonene, terpinen-4-ol, α-santalol, geraniol, furanodesma 1,3-diene, linalyl acetate, isobutyl angelicate, patchouli alcohol, benzyl acetate, carotol, α-himacalene, estragol (methyl chavicol), sabinene, and β-phenethyl alcohol. These fragrance components are known to be components found in natural fragrances that can be extracted from plants.

[0034] Fragrance region A1 is the area of ​​the adhesive layer 21 that surrounds the needle sheet 3 in a plan view. In other words, fragrance region A1 is the area on the surface of the adhesive layer 21 to which fragrance components are attached. Functional region A2 is the area of ​​the adhesive layer 21 to which the needle sheet 3 is attached. Functional region A2 can perform various functions depending on the effective skin-beautifying ingredients contained in the needle sheet 3, such as moisturizing function, whitening function, and dullness improvement function.

[0035] It should be noted that, due to the characteristics of the fragrance components, fragrance components may adhere to areas other than the fragrance area A1 (so-called "fragrance transfer"). If fragrance transfer occurs, priority will be given to designating the functional area A2, and the other areas will be designated as the fragrance area A1. In other words, the microneedle sheet 1 of this embodiment may have fragrance adhering to other components such as the needle sheet 3 and the protective plate 4. In the microneedle sheet 1 of this embodiment, it is sufficient that the fragrance area A1 has the strongest degree of fragrance component adhesion.

[0036] Here, the adhesive layer 21 has two characteristics for adhering to the object to be adhered to. One is that the surface of the adhesive layer 21 has numerous irregularities, and the other is that it generates intermolecular forces between the adhesive layer 21 and the object to be adhered to. Due to these characteristics, the adhesive sheet 2 is difficult to peel off from the skin. As a result of diligent research, the inventors of this application have discovered a scented microneedle sheet 1 to which fragrance components adhere, by utilizing the above two characteristics of the adhesive layer 21. That is, the fragrance components penetrate between the irregularities of the adhesive layer 21, and intermolecular forces act between the fragrance components and the adhesive layer 21, making it possible to provide a scented microneedle sheet 1 that provides a long-lasting fragrance.

[0037] Conventional microneedle sheets include a drying process in their manufacturing process, making it difficult to obtain microneedle sheets with a long-lasting fragrance because the fragrance contained in the raw materials evaporates. Furthermore, even if fragrance is included in the raw materials, there is a risk that the fragrance may cause skin irritation if it comes into contact with the skin for a long time. In contrast, the microneedle sheet 1 of this embodiment does not contain fragrance. The microneedle sheet 1 can release a long-lasting fragrance while preventing skin irritation caused by fragrance.

[0038] <Regarding the manufacturing method> Next, with further reference to Figure 2, the manufacturing method of the scented microneedle sheet 1 according to this embodiment will be described.

[0039] First, a mold having micro-recesses is prepared (preparation step S1). The shape of the micro-recesses corresponds to the micro-protrusions 30. The mold can be created by various methods, such as injection molding, press molding, laser irradiation, or 3D printing.

[0040] Next, the prepared mold is filled with the raw materials for the needle sheet 3 (filling step S2). The raw materials for the needle sheet 3 in this embodiment include, for example, sodium hyaluronate, glycerin, water, and sodium dilauroyl glutamate lysine. In addition to the effective skin-beautifying ingredients, the raw materials may contain various components such as moisturizers, antibacterial agents, thickeners, emulsifiers, pH adjusters, antioxidants, and solvents, but they do not contain fragrances. This prevents skin irritation caused by fragrances.

[0041] Next, the mold filled with the raw materials is dried (drying step S3). In drying step S3, any drying method is required to dry the raw materials, and various drying methods can be used, such as room temperature drying, forced air drying, or heated drying. In the case of heated drying, care should be taken to prevent the raw materials containing effective skin-beautifying ingredients from denature. As a result, the raw materials filled in the mold solidify, and the needle sheet before processing is formed. After drying step S3, the dried needle sheet is processed into the desired shape (processing step S4). Processing step S4 may include, for example, die-cutting to punch out the needle sheet into the desired shape, or needle molding to extract only the needle portion from the needle sheet formed in the mold.

[0042] Next, an adhesive sheet is attached to the other side 32 of the needle sheet 3 (attachment step S5). In this embodiment, the adhesive sheet is attached to the mold so as to cover the other side 32 of the needle sheet 3. The adhesive sheet and / or mold in this state are then die-cut into the desired shape to obtain an untreated microneedle sheet (second processing step S6). If the mold is also die-cut at the same time, the mold functions as a "protective plate 4" that protects the fine protrusions 30 of the microneedle sheet. In other words, the fine protrusions 30 of the microneedle sheet in this embodiment are manufactured without ever being peeled off the mold, so the surface that is attached to the skin can be kept hygienic.

[0043] Next, the untreated microneedle sheet is held for a certain period of time inside a housing filled with fragrance components of the fragrance. This causes at least the fragrance components to adhere to the adhesive sheet 2, completing the scented microneedle sheet 1 (fragrance component attachment step S7). The fragrance is a liquid component such as essential oil, aroma oil, perfume, etc., and includes fragrance components, which are volatile gaseous components that adhere to the adhesive sheet 2. In other words, the fragrance components are what remains after the volatile components of the fragrance have evaporated. Thus, according to the manufacturing method of this embodiment, the fragrance (fragrance components) does not undergo a drying process, so it is possible to prevent the loss or deterioration of the fragrance components.

[0044] The fragrance contains one or more fragrance components, and various ones can be used according to the needs of the user. The fragrance of this embodiment contains at least one fragrance selected from the group consisting of lavender, geranium, rosemary, sweet orange, sweet marjoram, grapefruit, sandalwood, bergamot, lemon, frankincense, ylang-ylang, roman chamomile, clarisse, juniper berry, neroli, rose, carrot seed, cypress, cedarwood, jasmine, basil, patchouli, palmarosa, petitgrain, myrrh, rosewood. Table 1 is a table showing the main fragrances and the main fragrance components contained therein.

[0045]

[0046] According to the manufacturing method of the micro needle sheet 1 of this embodiment, although it does not contain a fragrance, fragrance components are attached. Thereby, it is possible to prevent skin roughness caused by the fragrance, and even users with sensitive skin can use the scented micro needle sheet. In addition, in the micro needle sheet market where it has been conventionally necessary to avoid containing a fragrance, it is possible to provide a micro needle sheet having a new added value. That is, the micro needle sheet can add not only the beauty effect by the needle sheet but also the effects derived from fragrance components such as the relaxation effect and refreshing feeling by the fragrance components, which were difficult to impart with conventional micro needle sheets.

[0047] (Modified Example) Next, referring to FIGS. 1 and 3, a modified example of the manufacturing method of the scented micro needle sheet 1 of the above embodiment will be described. The manufacturing method of the micro needle sheet 1 of the modified example is basically the same as the manufacturing method of the above embodiment, but is different in that an adhesive sheet with a fragrance attached in advance is prepared.

[0048] First, an adhesive sheet is prepared (adhesive sheet preparation step S10). The prepared adhesive sheet is held in a housing filled with the fragrance components of the fragrance for a certain period of time to attach the fragrance components (fragrance component attachment step S11).

[0049] Steps S11 onward are substantially the same as the manufacturing method according to the above embodiment. Specifically, a mold having fine recesses is prepared (preparation step S12). The raw material for the needle sheet 3 is filled into the prepared mold (filling step S13). The mold filled with the raw material is dried (drying step S14). After the drying step S14, the dried needle sheet is processed into a desired shape (processing step S15). An adhesive sheet with fragrance components attached is attached to the needle sheet 3 after the processing step S15 (attachment step S16), and the adhesive sheet and / or mold are processed into a desired shape (second processing step S17). This produces a fragranced microneedle sheet 1.

[0050] According to the manufacturing method of this embodiment, since the fragrance component is initially attached only to the adhesive sheet, the fragrance component can be evenly applied to the entire adhesive layer. Modifications of the manufacturing method of the above embodiment can be suitably used, especially when manufacturing in large batches.

[0051] In the fragrance component attachment step S11 of the above embodiment, the fragrance component is attached by holding the adhesive sheet inside a housing filled with fragrance components for a certain period of time. However, the fragrance component attachment step S11 may also be performed by directly spraying or applying the fragrance to the adhesive sheet. In this case, it should be noted that the fragrance must be sufficiently volatile so as not to cause skin irritation.

[0052] Next, the present invention will be described in more detail with reference to examples, but the present invention is not limited to these examples.

[0053] <Evaluation test on the effects of scented microneedle sheets on users' psychological state> In this test, scented needle sheets were applied to the mouth area (nasolabial folds) of users, and the effects of the scented microneedle sheets on users were evaluated.

[0054] (Test Method) Referring to Table 2, the psychological state (mood) of seven users before and after using the microneedle sheets was evaluated on a 5-point scale from A to I. First, the mood before using the product was evaluated, and then two microneedle sheets were applied to each side of the nasolabial folds for each evaluation test. After application, the users rested for 10 minutes, and then their mood after use was evaluated again on a scale from A to H. In this way, the change in the users' mood before and after using the microneedle sheets was evaluated for each of Example 1 and the Comparative Example. The Example and Comparative Example are as follows: Example 1: Scented microneedle sheet made using lavender fragrance (manufactured by Yamamoto Fragrance Co., Ltd.) Comparative Example: Conventional microneedle sheet (without fragrance components)

[0055]

[0056] (Test Results) The evaluation results are shown in Figure 4. Figure 4(a) shows the results of evaluating the psychological state of the comparative example before and after using the microneedle sheet for evaluation items A to I. Figure 4(b) shows the results of evaluating the psychological state of the example 1 before and after using the microneedle sheet for evaluation items A to I. Note that each value is the average value of the results of 7 users.

[0057] The evaluation results showed that in Example 1, all users tended to select positive moods for each evaluation item. In particular, the results for evaluation items D, F, and H indicated that the use of the scented microneedle sheet led to a greater tendency for users to feel relaxed, soothed, and calm. Furthermore, evaluation items A, B, C, and E, which did not show much improvement in the comparative example, all showed improvement in mood in Example 1. In other words, it was found that the sheet had the effect of making users feel relaxed, at ease, refreshed, and clear-headed. In addition, for evaluation items G and I, few users tended to select positive moods before use, but after use, the number of users selecting positive moods increased significantly. In other words, it was found that the use of the microneedle sheet in Example 1 had the effect of making users feel refreshed and invigorated.

[0058] Based on the above, it was found that the microneedle sheet according to this embodiment has the effect of enhancing relaxation during sleep and calming the mind, compared to conventional microneedle sheets.

[0059] <Evaluation Test on Fragrance Persistence of Scented Microneedle Sheets> In this test, the fragrance persistence of scented microneedle sheets was evaluated by storing them at room temperature after removing them from a sealed container.

[0060] (Test Method) Scented microneedle sheets were kept in a sealed container filled with fragrance components for 5 days and then removed and placed on a desk at room temperature (23°C). After standing for a predetermined time (0 hours, 1 hour, 3 hours, 5 hours, 8 hours, 24 hours), four users confirmed the strength of the fragrance of the scented microneedle sheets. The examples and evaluation criteria are as follows: Example 2: Scented microneedle sheet made using lavender fragrance (manufactured by Yamamoto Fragrance Co., Ltd.) Example 3: Scented microneedle sheet made using geranium fragrance (manufactured by Yamamoto Fragrance Co., Ltd.)

[0061] Rating Criteria 5: Very noticeable fragrance 4: Moderately noticeable fragrance 3: Noticeable fragrance 2: Not very noticeable fragrance 1: No noticeable fragrance at all

[0062] (Test Results) Figure 5 is a graph showing the evaluation results regarding the fragrance persistence of the microneedle sheet. Figure 5(a) shows the results of the fragrance persistence evaluation for Example 2. Figure 5(b) shows the results of the fragrance persistence evaluation for Example 3. Note that each value is the average of the results from four users.

[0063] The evaluation results showed that both Examples 2 and 3 exhibited good fragrance persistence for at least 5 hours. Furthermore, at 8 hours, the fragrance persisted, although not to the same level as immediately after the start of the evaluation. In addition, a slight fragrance persisted even at 24 hours.

[0064] Here, due to the nature of microneedle sheets being applied to the face, it is common practice to apply them after bathing or washing the face, leave them on while sleeping, allow the active skin-beautifying ingredients of the needle sheet to penetrate into the stratum corneum during sleep, and then remove them upon waking. In other words, it is sufficient for the fragrance to last throughout the night. Considering the results of Examples 1 to 3 together, the microneedle sheets of this example allow users to feel a pleasant fragrance after 3 hours, enabling them to relax and fall asleep. Furthermore, since the fragrance persists after 8 hours, a more refreshing and invigorating awakening can be expected. This shows that not only can the microneedle sheets provide the skin-beautifying effect they are known for, but they can also be expected to improve the quality of sleep.

[0065] Furthermore, the microneedle sheet of this embodiment allows for appropriate modification of the content or type of fragrance components and effective skin-beautifying components depending on the application. This enables its use in desired applications such as pharmaceuticals, quasi-drugs, medicated cosmetics, and cosmetics.

[0066] The embodiments disclosed herein should be considered in all respects to be illustrative and not restrictive. The scope of the present invention is indicated by the claims rather than by the foregoing description, and all modifications within the meaning and scope equivalent to the claims are intended to be included.

[0067] 1. Scented microneedle sheet, 2. Adhesive sheet, 3. Needle sheet, 4. Protective plate, 20. Base layer, 21. Adhesive layer, 30. Fine protrusions, A1. Fragrance area, A2. Functional area.

Claims

1. A scented microneedle sheet comprising an adhesive sheet including a base layer and an adhesive layer, and a needle sheet including fine protrusions containing an effective skin-beautifying ingredient, wherein the adhesive sheet includes a fragrance region to which fragrance components are attached and a functional region to which the needle sheet is attached.

2. The scented microneedle sheet according to claim 1, wherein the adhesive sheet and the needle sheet do not contain fragrance.

3. The scented microneedle sheet according to claim 1 or 2, wherein the fragrance component comprises one or more fragrance components selected from the group consisting of linalool, α-pinene, limonene, terpinen-4-ol, α-santalol, geraniol, furanodesma 1,3-diene, linalyl acetate, isobutyl angelicate, patchouli alcohol, benzyl acetate, carotol, α-himacalene, estragol (methyl chavicol), sabinene, and β-phenethyl alcohol.

4. The scented microneedle sheet according to claim 1 or 2, further comprising a protective plate that protects the fine protrusions at a position opposite one surface of the needle sheet.

5. A method for manufacturing a scented microneedle sheet, comprising the steps of: preparing a mold having fine recesses; filling the mold with raw materials for a needle sheet; drying the mold filled with the raw materials; processing the dried needle sheet into a desired shape; attaching an adhesive sheet to the needle sheet after the processing step; processing the adhesive sheet into a desired shape to obtain an untreated microneedle sheet; and attaching fragrance components of a fragrance to at least the adhesive sheet of the untreated microneedle sheet.

6. A method for manufacturing a scented microneedle sheet, comprising the steps of: preparing an adhesive sheet; attaching fragrance components of a fragrance to the adhesive sheet; preparing a mold having fine recesses; filling the mold with raw materials for a needle sheet; drying the mold filled with the raw materials; processing the dried needle sheet into a desired shape; attaching an adhesive sheet with fragrance components attached to the needle sheet after the processing step; and processing the adhesive sheet into a desired shape.

7. The method for manufacturing a scented microneedle sheet according to claim 5 or 6, wherein the step of attaching the fragrance components of the fragrance is a step of attaching the fragrance components to at least the adhesive sheet by holding it in a housing filled with the fragrance components of the fragrance for a certain period of time.

8. The method for producing a scented microneedle sheet according to claim 5 or 6, wherein the fragrance includes a fragrance component that adheres to the adhesive sheet.

9. The method for producing a scented microneedle sheet according to claim 5 or 6, wherein the fragrance comprises at least one fragrance selected from the group consisting of lavender, geranium, rosemary, sweet orange, sweet marjoram, grapefruit, sandalwood, bergamot, lemon, frankincense, ylang-ylang, Roman chamomile, clary sage, juniper berry, neroli, rose, carrot seed, cypress, cedarwood, jasmine, basil, patchouli, palmarosa, petitgrain, myrrh, and rosewood.

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