Personalized chronotherapy

A personalized chronotherapy system uses sensor data to determine an individual's circadian rhythm and adjust therapeutic administration, addressing the limitations of current chronotherapy by enhancing efficacy and reducing adverse effects through alignment with biological rhythms.

WO2026128116A1 Publication Date: 2026-06-18CAREFUSION 303 INC
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Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
CAREFUSION 303 INC
Filing Date
2025-10-31
Publication Date
2026-06-18

AI Technical Summary

⚠Technical Problem

Current chronotherapy practices do not account for an individual's unique and potentially shifting circadian rhythm, leading to suboptimal dosing times that may not align with the patient's biological rhythms, potentially reducing therapeutic efficacy and increasing adverse effects.

⚗Method used

A system and method for personalized chronotherapy that utilizes sensor data, including biomarkers like cortisol and melatonin, to determine an individual's circadian rhythm, and adjusts the administration of therapeutics using an infusion pump or dialysis machine based on a personalized therapeutic schedule aligned with the patient's circadian rhythm.

🎯Benefits of technology

Enhances therapeutic efficacy by aligning drug administration with circadian-dependent biological functions, reducing adverse effects, and improving treatment outcomes and patient quality of life.

✦ Generated by Eureka AI based on patent content.

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Abstract

Certain aspects of the disclosure provide techniques for personalized chronotherapy. An example method includes obtaining sensor data associated with one or more sensors; determining a circadian rhythm based on the sensor data; determining a control schedule, for a device configured to deliver a therapeutic, based on the circadian rhythm and pharmacological data associated with the therapeutic; and controlling the device in accordance with the control schedule.
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