Local targeting photodynamic therapy device for treating cancer and control method thereof

By using a light supply device with multiple independent light sources and a focusing section, combined with real-time endoscopic imaging to select the lesion site, local treatment with photodynamic therapy is achieved. This solves the problems of excessive light irradiation range and damage to adjacent tissues in existing technologies, and is suitable for the precise treatment of cervical cancer and other cancers.

CN114173893BActive Publication Date: 2025-12-30AMOS PHARM CO LTD
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Patent Information

Application Number
CN202080003911.3
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Priority Date
2020-06-23
Filing Date
2020-06-30
Publication Date
2025-12-30
Estimated Expiration
2041-03-20

AI Technical Summary

Technical Problem

Existing photodynamic therapy devices are difficult to effectively treat lesions locally while minimizing damage to adjacent normal tissues when treating cancers such as cervical cancer, especially considering the complications associated with surgical treatments and the problem of excessively wide light irradiation areas.

Method used

The light supply device consists of multiple independent light sources and a focusing unit. The light irradiation area of ​​the lesion site is selected through real-time endoscopic imaging. Light is irradiated only in the selected area. Local treatment is achieved by switching on and off the independent light sources and adjusting their intensity.

Benefits of technology

It achieves precise light irradiation of the lesion site, reducing damage to adjacent normal tissues, and is suitable for local treatment of early cervical cancer and other female cancers such as endometrial cancer, ovarian cancer, breast cancer, skin cancer and brain cancer.

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Abstract

The present invention relates to a local targeting photodynamic therapy device for treating cancer. In more detail, an endoscope is disposed at the center of the end of a probe for photodynamic therapy, and a plurality of optical fibers are disposed along the edge to irradiate a plurality of lights to a lesion site, wherein the plurality of optical fibers of the probe receive light from independent light sources to independently perform light irradiation. The present invention is a device for minimizing damage to unnecessary normal tissue by adjusting the light irradiation area, i.e., each independent light source determines a light irradiation area including a lesion site in a real-time image provided by an endoscope disposed at the end of the probe, and only causes the independent light source that irradiates the determined light irradiation area to emit light, thereby achieving local light irradiation, etc. The local targeting photodynamic therapy device of the present invention can treat a variety of cancers or tumors, including cervical cancer, female cancers (endometrial cancer, ovarian cancer, breast cancer), skin cancer, brain cancer, etc., which are small and can be treated locally.
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