A blood testing apparatus
By designing an integrated blood analyzer and utilizing sampling distribution and coordinated control of multiple detection devices, the problems of large blood sample volume and complex testing were solved, achieving efficient multi-parameter detection.
Patent Information
- Application Number
- CN202110258540.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2021-03-09
- Publication Date
- 2026-01-16
- Estimated Expiration
- 2041-03-09
AI Technical Summary
In existing technologies, routine blood parameters and specific protein parameters need to be detected in different instruments, resulting in a large demand for blood samples and a complex testing process.
Design a blood analyzer comprising a sampling and dispensing device, a routine blood test device, first and second specific protein test devices, and a control device. The control device coordinates sample collection and dispensing, enabling time overlap of multiple test devices, reducing sample volume requirements and simplifying the testing process.
It enables the simultaneous detection of routine blood parameters and first and second specific protein parameters with a small amount of blood sample, reducing patient discomfort and improving detection efficiency.
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Figure CN115046993B_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the technical field of medical equipment, in particular to a blood detector. BACKGROUND
[0002] In the clinical diagnosis of a hospital, not only the routine parameters of blood of a patient need to be obtained, but also certain specific protein parameters need to be obtained, so that a doctor can make a more accurate judgment and thus carry out targeted treatment.
[0003] The present application relates to the technical field of medical equipment, in particular to a blood detector. SUMMARY
[0004] The present application provides a blood detector to solve the technical problem that the routine parameters of blood and the specific protein parameters need to be detected in different instruments, resulting in a large demand for blood samples and a complex detection process.
[0005] To solve the above technical problem, one technical solution of the present application is to provide a blood detector, comprising:
[0006] A sampling and distributing device is configured to collect and distribute blood samples.
[0007] A routine blood detection device is configured to obtain the blood samples and detect the blood samples to obtain at least one routine blood parameter.
[0008] A first specific protein detection device includes at least two first reaction detection components, which are configured to obtain the blood samples and detect the blood samples to obtain a first specific protein parameter.
[0009] A second specific protein detection device includes at least one second reaction detection component, which is configured to obtain the blood samples and detect the blood samples to obtain a second specific protein parameter.
[0010] A control device is configured to control the sampling and distributing device to collect and distribute the blood samples, and control the routine blood detection device, the first specific protein detection device and the second specific protein detection device to detect respectively, and control the sampling and distributing device to start collecting and distributing the next blood sample before the routine blood detection device completes the detection of at least one routine blood parameter of the current blood sample, so that the two first reaction detection components have time overlap in the detection process.
[0011] In an embodiment, the first reaction detection component comprises a first reaction detection container and a first detection unit, the first reaction detection container is configured to contain the blood sample and a first specific protein detection reagent, so that the blood sample and the first specific protein detection reagent can be mixed and reacted in the first reaction detection container, and the first detection unit is configured to detect the blood sample mixed and reacted in the first reaction detection container to obtain the first specific protein parameter.
[0012] The second reaction detection component comprises a second reaction detection container and a second detection unit, the second reaction detection container is configured to contain the blood sample and a second specific protein detection reagent, so that the blood sample and the second specific protein detection reagent can be mixed and reacted in the second reaction detection container, and the second detection unit is configured to detect the blood sample mixed and reacted in the second reaction detection container to obtain the second specific protein parameter.
[0013] In an embodiment, the first reaction detection component comprises a first reaction container, a first detection container and a first detection unit, the first reaction container is configured to contain the blood sample and a first specific protein detection reagent, so that the blood sample and the first specific protein detection reagent can be mixed and reacted in the first reaction container, the first detection container is configured to receive the blood sample mixed and reacted in the first reaction container, and the first detection unit is configured to detect the blood sample in the first detection container to obtain the first specific protein parameter.
[0014] The second reaction detection component comprises a second reaction container, a second detection container and a second detection unit, the second reaction container is configured to contain the blood sample and a second specific protein detection reagent, so that the blood sample and the second specific protein detection reagent can be mixed and reacted in the second reaction container, the second detection container is configured to receive the blood sample mixed and reacted in the second reaction container, and the second detection unit is configured to detect the blood sample in the second detection container to obtain the second specific protein parameter.
[0015] In an embodiment, the first detection unit and the second detection unit are the same detection unit, which comprises a light source generator and a receiver, the light source generator is configured to emit detection light, and the receiver is configured to receive the detection light transmitted through the blood sample mixed with the first specific protein detection reagent and / or the detection light transmitted through the blood sample mixed with the second specific protein detection reagent.
[0016] In an embodiment, the number of the receivers is multiple, and the multiple receivers are arranged along the circumference of the light source generator.
[0017] In an embodiment, the number of the receivers is multiple, and the detection unit further comprises a light splitter configured to split the detection light emitted by the light source generator to form multiple detection sub-rays, one of the multiple receivers is configured to receive the detection sub-rays passing through the blood sample mixed with the first specific protein detection reagent, and another of the multiple receivers is configured to receive the detection sub-rays passing through the blood sample mixed with the second specific protein detection reagent.
[0018] In an embodiment, the first detection unit comprises a first light source generator configured to emit first detection light and a first receiver configured to receive the first detection light passing through the blood sample mixed with the first specific protein detection reagent, and the second detection unit comprises a second light source generator configured to emit second detection light and a second receiver configured to receive the second detection light passing through the blood sample mixed with the second specific protein detection reagent.
[0019] In an embodiment, the detection time of the first specific protein detection device is longer than the detection time of the second specific protein detection device, and the control device is configured to control the sampling and dispensing device to first dispense the blood sample to the first specific protein detection device and then to the second specific protein detection device after the blood sample is collected by the sampling and dispensing device.
[0020] In an embodiment, the blood routine parameter is a Diff parameter, an HCT parameter, a RET parameter, or an NRBC parameter, the first specific protein parameter is a CRP parameter, and the second specific protein parameter is a SAA parameter.
[0021] To solve the above technical problems, another technical solution adopted by the present application is to provide a blood detection method, comprising:
[0022] controlling a sampling and dispensing device to collect a blood sample and to dispense the blood sample to a blood routine detection device, at least two first reaction detection components of a first specific protein detection device, and a second reaction detection component of a second specific protein detection device, respectively;
[0023] controlling the blood routine detection device to detect the blood sample to obtain at least one blood routine parameter;
[0024] controlling the first specific protein detection device to detect the blood sample to obtain a first specific protein parameter;
[0025] controlling the second specific protein detection device to detect the blood sample to obtain a second specific protein parameter;
[0026] controlling the sampling and dispensing device to start collecting and dispensing the next blood sample before the blood routine detection device completes the detection of at least one blood routine parameter of the current blood sample, so that the two first reaction detection components exist time overlap in the detection process.
[0027] The blood detection instrument includes a sampling and dispensing device, a blood routine detection device, a first specific protein detection device, a second specific protein detection device, and a control device. The first specific protein detection device includes at least two first reaction detection components. The sampling and dispensing device is controlled by the control device to collect and dispense blood samples. The blood routine detection device, the first specific protein detection device, and the second specific protein detection device are controlled by the control device to detect blood routine parameters, first specific protein parameters, and second specific protein parameters, respectively. The blood detection instrument only needs to collect a small amount of blood sample to realize the detection of blood routine parameters, first specific protein parameters, and second specific protein parameters, which can reduce the pain of patients, simplify the detection process, and control the sampling and dispensing device to start collecting and dispensing the next blood sample before the blood routine detection device completes the detection of at least one blood routine parameter of the current blood sample, so that the two first reaction detection components exist time overlap in the detection process, which can realize the detection of multiple blood samples at the same time, thereby improving the efficiency of blood detection. BRIEF DESCRIPTION OF DRAWINGS
[0028] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the following will briefly introduce the drawings needed to be used in the embodiment description. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor based on these drawings.
[0029] Figure 1 is a structural schematic diagram of an embodiment of the blood detection instrument of the present application;
[0030] Figure 2 is a partial structural schematic diagram of an embodiment of the blood detection instrument of the present application;
[0031] Figure 3 is a flowchart of the sampling and detection process in an embodiment of the blood detection instrument of the present application;
[0032] Figure 4 is a structural schematic diagram of the first specific protein detection device in an embodiment of the blood detection instrument of the present application;
[0033] Figure 5 is a structural schematic diagram of the first specific protein detection device in another embodiment of the blood detector of the present application;
[0034] Figure 6 is a structural schematic diagram of the first specific protein detection device in another embodiment of the blood detector of the present application;
[0035] Figure 7 is a flow schematic diagram of an embodiment of the blood detection method of the present application;
[0036] Figure 8 is a structural schematic diagram of another embodiment of the blood detector of the present application;
[0037] Figure 9 is a partial structural schematic diagram of another embodiment of the blood detector of the present application;
[0038] Figure 10 is a flow schematic diagram of the sample splitting and detection process in another embodiment of the blood detector of the present application;
[0039] Figure 11 is a flow schematic diagram of another embodiment of the blood detection method of the present application;
[0040] Figure 12 is a structural schematic diagram of another embodiment of the blood detector of the present application;
[0041] Figure 13 is a partial structural schematic diagram of another embodiment of the blood detector of the present application;
[0042] Figure 14 is a flow schematic diagram of the sample splitting and detection process in another embodiment of the blood detector of the present application;
[0043] Figure 15 is a flow schematic diagram of another embodiment of the blood detection method of the present application;
[0044] Figure 16 is a structural schematic diagram of another embodiment of the blood detector of the present application;
[0045] Figure 17 is a partial structural schematic diagram of another embodiment of the blood detector of the present application;
[0046] Figure 18 is a flow schematic diagram of the sample splitting and detection process in another embodiment of the blood detector of the present application. DETAILED DESCRIPTION
[0047] Clearly, the described embodiments are only a part of all embodiments of the present application. Based on the embodiments in the present application, all other embodiments obtained by those ordinarily skilled in the art without creative effort are within the scope of the present application.
[0048] The terms "first", "second", etc. are used only for the purpose of description, and should not be understood as indicating or implying relative importance or implying the number of the technical features indicated. In the description of the present application, the meaning of "multiple" is at least two, for example, two, three, etc., unless otherwise specifically limited. In addition, the terms "include" and "have" and any variations thereof are intended to cover non-exclusive inclusion. For example, a process, method, system, product or device that includes a series of steps or units is not limited to the listed steps or units, but can optionally include steps or units not listed, or can optionally include other steps or units inherent to the process, method, product or device. The term "and / or", only describes the relationship between the associated objects, which means that there can be three relationships, for example, A and / or B, which means that there are three cases: A exists alone, A and B exist together, and B exists alone. In addition, the character " / " in this paper generally represents an "or" relationship between the front and back associated objects.
[0049] Referring to Figures 1 to 3The blood detector 10 in the embodiment comprises a sampling and distributing device 110, a routine blood test device 120, a first specific protein test device 130, a second specific protein test device 140, and a control device 150. The sampling and distributing device 110 is used to collect and distribute blood samples. The routine blood test device 120 is used to collect and test blood samples to obtain at least one routine blood parameter. The first specific protein test device 130 is used to collect and test blood samples to obtain a first specific protein parameter. The second specific protein test device 140 is used to collect and test blood samples to obtain a second specific protein parameter. The control device 150 controls the sampling and distributing device 110 to collect and distribute blood samples through a liquid path system 151, and controls the routine blood test device 120, the first specific protein test device 130, and the second specific protein test device 140 to test respectively, so that the blood detector 10 can realize the detection of routine blood parameters, first specific protein parameters, and second specific protein parameters by collecting less blood samples, which can reduce the pain of patients and simplify the detection process. The control device 150 controls the sampling and distributing device 110 to collect and distribute the next blood sample before the routine blood test device 120 completes the detection of at least one routine blood parameter of the current blood sample, which can realize the detection of multiple blood samples at the same time, and further improve the efficiency of blood detection.
[0050] In the embodiment, the detection time of the first specific protein test device 130 is greater than the detection time of the second specific protein test device 140, and the detection time of the first specific protein test device 130 and the detection time of the second specific protein test device 140 are both greater than the detection time of the routine blood test device 120. The control device 150 can be used to control the sampling and distributing device 110 to distribute the blood sample to the first specific protein test device 130 first, then to the second specific protein test device 140, and finally to the routine blood test device 120, so that the detection time sequence of routine blood parameters, first specific protein parameters, and second specific protein parameters is more reasonable, and the efficiency of blood detection is further improved.
[0051] In the embodiment, the routine blood parameter can be a Diff parameter, an HCT parameter, a RET parameter, or an NRBC parameter, the first specific protein parameter can be a CRP parameter, and the second specific protein parameter can be a SAA parameter.
[0052] In the embodiment, the sampling and distributing device 110 comprises a sampling needle 111, a first driving member 112, and a second driving member 113. The first driving member 112 is used to drive the sampling needle 111 to move on a vertical track 114, and the second driving member 113 is used to drive the sampling needle 111 to move on a horizontal track 115 to realize sampling and distribution.
[0053] The sampling dispensing process of the sampling dispensing device 110 is as follows: the sampling needle 111 is driven by the first driving member 112 and the second driving member 113 to extend into the blood sample, the syringe 121 provides negative pressure, the sampling needle 111 sucks the blood sample, then the valves LV21 and LV22 are opened, the syringe 122 inputs the cleaning liquid to the swab, and the sampling needle 111 is driven by the first driving member 112 to move upward relative to the swab 116, so that the swab 116 completes the cleaning of the outer wall of the sampling needle 111.
[0054] The valves LV21 and LV23 are opened, the syringe 122 inputs the dilution liquid to the reaction pool 117, and the sampling needle 111 is driven by the first driving member 112 and the second driving member 113 to the reaction pool 117 (for example, an RBC (red blood cell) reaction pool), the first specific protein detection device 130, and the second specific protein detection device 140, respectively, and the syringe 121 provides positive pressure to distribute the blood sample to the reaction pool 117, the first specific protein detection device 130, and the second specific protein detection device 140, respectively.
[0055] The valves LV21 and LV24 are opened, the syringe 122 inputs the cleaning liquid to the syringe 121, and the syringe 121 inputs the cleaning liquid to the sampling needle 111, so that the cleaning liquid flows out of the sampling needle 111, completing the cleaning of the inner wall of the sampling needle 111.
[0056] After the sampling of the reaction pool 117 is completed, the valve LV25 is opened to inject bubbles into the reaction pool 117 to drive the disturbance of the liquid in the reaction pool 117, completing the mixing of the blood sample and the dilution liquid.
[0057] The valve LV26 is opened to perform RBC detection on the mixed liquid.
[0058] After the detection is completed, the valve LV27 is opened to discharge the waste liquid in the reaction pool 117.
[0059] The valves LV21 and LV23 are opened, the syringe 122 inputs the cleaning liquid to the reaction pool 117, then the valve LV27 is opened to discharge the cleaning liquid in the reaction pool 117, completing the cleaning of the reaction pool 117.
[0060] In the embodiment, the first specific protein detection device 130 comprises at least one first reaction detection container 131 and a first detection unit 132. The first reaction detection container 131 is used for containing a blood sample and a first specific protein detection reagent, so that the blood sample and the first specific protein detection reagent can be mixed and reacted in the first reaction detection container 131. The first detection unit 132 is used for detecting the mixed blood sample in the first reaction detection container 131 to obtain a first specific protein parameter. By implementing the mixing and reaction and the detection in the first reaction detection container 131, the structure of the first specific protein detection device 130 can be more simple and compact, and the occupied space can be smaller.
[0061] In the embodiment, the second specific protein detection device 140 comprises at least one second reaction detection container 141 and a second detection unit (not shown in the figure). The second reaction detection container 141 is used for containing a blood sample and a second specific protein detection reagent, so that the blood sample and the second specific protein detection reagent can be mixed and reacted in the second reaction detection container 141. The second detection unit is used for detecting the mixed blood sample in the second reaction detection container 141 to obtain a second specific protein parameter. By implementing the mixing and reaction and the detection in the second reaction detection container 141, the structure of the second specific protein detection device 140 can be more simple and compact, and the occupied space can be smaller.
[0062] In the embodiment, the first specific protein parameter is taken as the CRP parameter, and the second specific protein parameter is taken as the SAA parameter.
[0063] The CRP parameter detection process is as follows: the pump 101 is started, the valves LV01 and LV07 are opened, and the first reaction detection container 131 and the second reaction detection container 141 are emptied. The valves LV02 and LV03 are opened, and the quantitative pump 102 adds the CRP-R1 reagent into the first reaction detection container 131. At the same time, the sampling and dispensing device 110 sends a quantitative blood sample into the first reaction detection container 131. The valve LV06 is opened, and the syringe 104 alternately provides positive pressure and negative pressure, so that the blood sample and the CRP-R1 reagent in the first reaction detection container 131 are mixed. Then, the valves LV04 and LV05 are opened, and the quantitative pump 103 adds the CRP-R2 reagent into the first reaction detection container 131. The valve LV06 is opened, and the syringe 104 alternately provides positive pressure and negative pressure, so that the blood sample and the CRP-R2 reagent in the first reaction detection container 131 are mixed. The first detection unit 132 detects the mixed blood sample in the first reaction detection container 131 with the CRP-R1 reagent and the CRP-R2 reagent. After the detection is completed, the pump 101 is started, the valve LV01 is opened, and the waste liquid in the first reaction detection container 131 is emptied. The first reaction detection container 131 can be cleaned by the syringe 104.
[0064] The SAA parameter detection process is as follows: after the CRP sampling is completed, the sampling distribution device 110 starts the SAA sampling, i.e., the quantitative blood sample is sent into the second reaction detection container 141, at the same time, the valves LV08 and LV09 are opened, the quantitative pump 105 adds the SAA-R1 reagent into the second reaction detection container 141, the valve LV12 is opened, and the syringe 107 alternately provides positive pressure and negative pressure to mix the blood sample in the second reaction detection container 141 with the SAA-R1 reagent; then the valves LV08 and LV09 are opened, the quantitative pump 106 adds the SAA-R2 reagent into the second reaction detection container 141, the valve LV12 is opened, and the syringe 107 alternately provides positive pressure and negative pressure to mix the blood sample in the second reaction detection container 141 with the SAA-R2 reagent; the second detection unit detects the blood sample mixed with the SAA-R1 reagent and the SAA-R2 reagent in the second reaction detection container 141, after the detection is completed, the pump 101 is started, the valve LV07 is opened, the waste liquid in the second reaction detection container 141 is emptied, and the second reaction detection container 141 can be cleaned by the syringe 107.
[0065] Referring to Figure 4 In the embodiment, the first detection unit 132 and the second detection unit can be the same detection unit, which includes a light source generator 133 and a receiver 134, the light source generator 133 is used to emit detection light, and the receiver 134 is used to receive the detection light that passes through the blood sample mixed with the first specific protein detection reagent and / or the detection light that passes through the blood sample mixed with the second specific protein detection reagent, so that the detection of the first specific protein parameter and the second specific protein parameter is realized by the same detection unit, which can make the structure of the first specific protein detection device 130 and the second specific protein detection device 140 more simple and compact, and occupy less space.
[0066] In the embodiment, a driving member (not shown in the figure) can be arranged to drive the receiver 134 to move to correspond to the first reaction detection container 131 and the second reaction detection container 141 respectively, so as to realize the detection of the blood sample.
[0067] Referring to Figure 5 In another specific embodiment, the detection unit 160 includes a light source generator 161 and a plurality of receivers 162, the plurality of receivers 162 are arranged along the circumference of the light source generator 161 to correspond to the first reaction detection container 131 and the second reaction detection container 141 respectively, the positions of the receivers 162 are relatively fixed, the reliability is higher, and the same light source generator 161 can be shared, so that the structure of the first specific protein detection device 130 and the second specific protein detection device 140 is more simple and compact, and occupies less space.
[0068] Referring to Figure 6 In another specific embodiment, the detection unit 170 comprises a light source generator 171, a plurality of receivers 172, and a light splitter 173, the light splitter 173 is used for splitting the detection light emitted by the light source generator 171 to form a plurality of detection sub-rays, one of the plurality of receivers 172 is used for receiving the detection sub-rays transmitted through the blood sample mixed with the first specific protein detection reagent, and another of the plurality of receivers 172 is used for receiving the detection sub-rays transmitted through the blood sample mixed with the second specific protein detection reagent.
[0069] In other embodiments, the first detection unit 132 and the second detection unit can also be independent detection units. For example, the first detection unit 132 can comprise a first light source generator and a first receiver, the first light source generator is used for emitting first detection light, and the first receiver is used for receiving the first detection light transmitted through the blood sample mixed with the first specific protein detection reagent; the second detection unit comprises a second light source generator and a second receiver, the second light source generator is used for emitting second detection light, and the second receiver is used for receiving the second detection light transmitted through the blood sample mixed with the second specific protein detection reagent. The first light source generator and the first receiver, the second light source generator and the second receiver are similar to the structure of the light source generator 133 and the receiver 134, and will not be described here.
[0070] In other embodiments, the reaction and detection process of specific protein detection can also be carried out in different containers respectively. For example, the first specific protein detection device 130 can comprise at least one first reaction container (not shown in the figure), at least one first detection container (not shown in the figure), and the first detection unit 132, the first reaction container is used for accommodating the blood sample and the first specific protein detection reagent, so that the blood sample and the first specific protein detection reagent can be mixed and reacted in the first reaction container, the first detection container is used for receiving the blood sample mixed in the first reaction container, and the first detection unit 132 detects the blood sample in the first detection container to obtain the first specific protein parameter. By mixing and reacting in the first reaction container and then detecting in the first detection container, each detection step can be more explicit, avoiding detection before the mixture is fully mixed, and the reliability of the first specific protein detection device 130 can be improved.
[0071] In other embodiments, the second specific protein detection device 140 can include at least one second reaction container, at least one second detection container, and a second detection unit, the second reaction container is used to accommodate the blood sample and the second specific protein detection reagent, so that the blood sample and the second specific protein detection reagent can be mixed and reacted in the second reaction container, the second detection container is used to receive the blood sample mixed and reacted in the second reaction container, and the second detection unit detects the blood sample in the second detection container to obtain the second specific protein parameter. By mixing and reacting in the second reaction container and then detecting in the second detection container, each detection step can be more explicit, avoiding detection before the blood sample is fully mixed, and the reliability of the second specific protein detection device 140 can be improved.
[0072] Referring to Figure 7 , the blood detection method includes the following steps:
[0073] S181, control the sampling and distribution device to collect the blood sample and distribute the blood sample to the blood routine detection device, the first specific protein detection device, and the second specific protein detection device, respectively.
[0074] In this embodiment, the order of the sampling and distribution device distributing the blood sample can be the first specific protein detection device, the second specific protein detection device, and the blood routine detection device.
[0075] S182, control the blood routine detection device to detect the blood sample to obtain at least one blood routine parameter.
[0076] S183, control the first specific protein detection device to detect the blood sample to obtain the first specific protein parameter.
[0077] S184, control the second specific protein detection device to detect the blood sample to obtain the second specific protein parameter.
[0078] The present application only needs to collect a small amount of blood sample to realize the detection of blood routine parameters, first specific protein parameters, and second specific protein parameters, which not only reduces the pain of patients, but also simplifies the detection process.
[0079] S185, before the blood routine detection device completes the detection of at least one blood routine parameter of the current blood sample, the sampling and distribution device starts to collect and distribute the next blood sample.
[0080] By reasonably controlling the sampling and distribution device, the blood routine detection device, the first specific protein detection device, and the second specific protein detection device, the detection of multiple blood samples can be realized at the same time, and the efficiency of blood detection can be improved.
[0081] Referring to Figures 8 to 10The blood detector 20 further includes a sampling and dispensing device 210, a routine blood test device 220, a first specific protein test device 230, and a control device 240. The sampling and dispensing device 210 is configured to collect and dispense blood samples. The routine blood test device 220 is configured to obtain and test the blood samples to obtain at least one routine blood parameter. The first specific protein test device 230 includes at least two first reaction test components 231, which are configured to obtain and test the blood samples to obtain a first specific protein parameter. The control device 240 is configured to control the sampling and dispensing device 210 to collect and dispense the blood samples through a liquid path system 241, and to control the routine blood test device 220 and the first specific protein test device 230 to perform the tests, respectively. As a result, the blood detector 20 can collect less blood samples to test the routine blood parameters and the first specific protein parameter, thereby reducing the pain of patients and simplifying the testing process. Moreover, the control device 240 controls the sampling and dispensing device 210 to collect and dispense the next blood sample before the routine blood test device 220 completes the test of the at least one routine blood parameter of the current blood sample, so that the two first reaction test components 231 overlap in time during the testing process, and the first specific protein parameter of multiple blood samples can be tested simultaneously, thereby improving the efficiency of blood testing.
[0082] In this embodiment, the detection time of the first specific protein test device 230 is greater than the detection time of the routine blood test device 220. The control device 240 can be configured to control the sampling and dispensing device 210 to dispense the blood sample to the first specific protein test device 230 first, and then to the routine blood test device 220, so that the detection time of the routine blood parameters and the first specific protein parameter is more reasonable, and the efficiency of blood testing is further improved.
[0083] In this embodiment, the routine blood parameter can be a Diff parameter, an HCT parameter, a RET parameter, or an NRBC parameter, and the first specific protein parameter can be a CRP parameter or an SAA parameter.
[0084] In this embodiment, the blood detector 20 further includes a second specific protein test device (not shown in the figure), which includes at least one second reaction test component, and is configured to obtain and test the blood samples to obtain a second specific protein parameter. The second specific protein parameter can be a CRP parameter or an SAA parameter.
[0085] In this embodiment, the first reaction detection component 231 includes a first reaction detection container 232 and a first detection unit (not shown in the figure). The first reaction detection container 232 is used to contain a blood sample and a first specific protein detection reagent, so that the blood sample and the first specific protein detection reagent can be mixed and reacted in the first reaction detection container 232. The first detection unit is used to detect the blood sample mixed in the first reaction detection container 232 to obtain the first specific protein parameter.
[0086] In this embodiment, the structure of the second reaction detection component is similar to that of the first reaction detection component 231, and will not be described again here.
[0087] In this embodiment, CRP parameter is used as an example to illustrate the first specific protein parameter. When detecting the CRP parameter, pump 201 is turned on, emptying the two first reaction detection containers 232, and the sample is dispensed via sampling distribution device 210. Figure 9 In the process of first specific protein sampling 1, the blood pressure sample is allocated to one of the two first reaction detection containers 232, and first specific protein sampling 2, the blood pressure sample is allocated to the other of the two first reaction detection containers 232. CRP-R1 reagent is added through metering pump 202, and CRP-R2 reagent is added through metering pump 203. The blood sample and reagents are then mixed through syringe 204. The specific process is similar to the CRP parameter detection process of the blood analyzer 10 described above, and will not be repeated here.
[0088] In this embodiment, the structure of the first detection unit is similar to that of the first detection unit 132 in the blood analyzer 10 described above, and will not be repeated here.
[0089] In other embodiments, the first reaction detection component may also include a first reaction container, a first detection container, and a first detection unit, and the second reaction detection component may also include a second reaction container, a second detection container, and a second detection unit, similar to the structure of the first specific protein detection device 130 in the blood analyzer 10 described above, and will not be described again here.
[0090] See Figure 11 Another embodiment of the blood detection method of the present invention includes:
[0091] S251, Control the sampling and dispensing device to collect blood samples and dispense the blood samples to at least two first reaction detection components of the blood routine detection device and the first specific protein detection device respectively.
[0092] In this embodiment, the order in which the sampling and dispensing device dispenses blood samples can be the first specific protein detection device and the routine blood test device.
[0093] S252, control the blood routine detection device to detect the blood sample to obtain at least one blood routine parameter.
[0094] S253, control the first specific protein detection device to detect the blood sample to obtain the first specific protein parameter.
[0095] The present application only needs to collect a small amount of blood sample to realize the detection of blood routine parameters and the first specific protein parameters, which not only reduces the pain of patients, but also simplifies the detection process.
[0096] S254, before the blood routine detection device completes the detection of at least one blood routine parameter of the current blood sample, the sampling and distribution device starts the collection and distribution of the next blood sample, so that the two first reaction detection components exist time overlap in the detection process.
[0097] Through reasonable control of the sampling and distribution device, the blood routine detection device and the first specific protein detection device, the detection of multiple blood samples can be realized at the same time, thereby improving the efficiency of blood detection.
[0098] Referring to Figures 12 to 14 , the blood detection instrument 30 another embodiment includes sampling and distribution device 310, blood routine detection device 320, first specific protein detection device 330, second specific protein detection device 340 and control device 350, sampling and distribution device 310 is used for collecting blood sample and distribution, blood routine detection device 320 is used for obtaining blood sample and detecting blood sample to obtain at least one blood routine parameter, first specific protein detection device 330 includes at least two first reaction detection components 331, for obtaining blood sample and detecting blood sample to obtain the first specific protein parameter, second specific protein detection device 340 includes at least one second reaction detection component 341, for obtaining blood sample and detecting blood sample to obtain the second specific protein parameter, control device 350 is used for controlling the sampling and distribution device 310 to collect blood sample, distribute blood sample through the liquid path system 351, control blood routine detection device 320, first specific protein detection device 330 and second specific protein detection device 340 to detect respectively, so that the blood detection instrument 30 only needs to collect a small amount of blood sample to realize the detection of blood routine parameters and the first specific protein parameters, which not only reduces the pain of patients, but also simplifies the detection process, and before the blood routine detection device 320 completes the detection of at least one blood routine parameter of the current blood sample, the sampling and distribution device 310 starts the collection and distribution of the next blood sample, so that the two first reaction detection components 331 exist time overlap in the detection process, which can realize the detection of multiple blood samples of the first specific protein parameters at the same time, thereby improving the efficiency of blood detection.
[0099] In the embodiment, the detection time of the first specific protein detection device 330 is greater than the detection time of the second specific protein detection device 340, and the detection time of the first specific protein detection device 330 and the detection time of the second specific protein detection device 340 are both greater than the detection time of the routine blood detection device 320. The control device 350 can be used to control the sampling and distribution device 310 to distribute the blood sample to the first specific protein detection device 330 first, then to the second specific protein detection device 340, and finally to the routine blood detection device 320 after the blood sample is collected, so that the detection time sequence of the routine blood parameters, the first specific protein parameters and the second specific protein parameters is more reasonable, and the efficiency of blood detection is further improved.
[0100] In the embodiment, the routine blood parameters can be Diff parameters, HCT parameters, RET parameters or NRBC parameters, and the first specific protein parameters and the second specific protein parameters can be CRP parameters or SAA parameters.
[0101] In the embodiment, the structures of the first reaction detection assembly 331 and the second reaction detection assembly 341 are similar to those of the first reaction detection assembly 231 of the blood detector 20, and will not be described here.
[0102] In the embodiment, the first specific protein parameters are CRP parameters and the second specific protein parameters are SAA parameters. The CRP parameter detection of the blood detector 30 is realized by the pump 301, the quantitative pumps 302 and 303 and the injector 404, and the detection process is similar to the CRP parameter detection process of the blood detector 10. The SAA parameter detection process is also similar to the SAA parameter detection process of the blood detector 10, and will not be described here.
[0103] In the embodiment, the structure of the first detection unit is similar to that of the first detection unit 132 of the blood detector 10, and will not be described here.
[0104] Referring to Figure 15 , another embodiment of the blood detection method of the application comprises:
[0105] S361, the sampling and distribution device collects the blood sample and distributes the blood sample to the routine blood detection device, at least two first reaction detection assemblies of the first specific protein detection device and the second reaction detection assembly of the second specific protein detection device.
[0106] In the embodiment, the sampling and distribution device can distribute the blood sample in the order of the first specific protein detection device, the second specific protein detection device and the routine blood detection device.
[0107] S362, the routine blood detection device detects the blood sample to obtain at least one routine blood parameter.
[0108] S363, control the first specific protein detection device to detect the blood sample to obtain the first specific protein parameter.
[0109] S364, control the second specific protein detection device to detect the blood sample to obtain the second specific protein parameter.
[0110] The present application only needs to collect a small amount of blood sample to realize the detection of blood routine parameters, the first specific protein parameter and the second specific protein parameter, which can not only alleviate the pain of patients, but also simplify the detection process.
[0111] S365, before the blood routine detection device completes the detection of at least one blood routine parameter of the current blood sample, control the sampling and distributing device to start the collection and distribution of the next blood sample, so that the two first reaction detection components exist time overlap in the detection process.
[0112] Through the reasonable control of the sampling and distributing device, the blood routine detection device, the first specific protein detection device and the second specific protein detection device, the detection of multiple blood samples can be realized at the same time, and the efficiency of blood detection can be improved.
[0113] Referring to Figures 16 to 18The blood detector 40 includes a sample distribution device 410, a blood routine test device 420, a first specific protein test device 430, a second specific protein test device 440, and a control device 450. The sample distribution device 410 is used to collect and distribute blood samples. The blood routine test device 420 is used to obtain and test blood samples to obtain at least one blood routine parameter. The first specific protein test device 430 includes at least two first reaction test components 431, which are used to obtain and test blood samples to obtain a first specific protein parameter. The second specific protein test device 440 includes at least two second reaction test components 441, which are used to obtain and test blood samples to obtain a second specific protein parameter. The control device 450 is used to control the sample distribution device 410 to collect and distribute blood samples through a liquid path system 451, and control the blood routine test device 420, the first specific protein test device 430, and the second specific protein test device 440 to perform detection respectively. As a result, the blood detector 40 only needs to collect a small amount of blood sample to realize the detection of blood routine parameters and first specific protein parameters, which not only reduces the pain of patients, but also simplifies the detection process. Before the blood routine test device 420 completes the detection of at least one blood routine parameter of the current blood sample, the sample distribution device 410 is controlled to start the collection and distribution of the next blood sample, so that the two first reaction test components 431 and the two second reaction test components 441 have time overlap during the detection process, which can simultaneously realize the detection of the first specific protein parameters of multiple blood samples, thereby improving the efficiency of blood detection.
[0114] In this embodiment, the structure and detection process of the first specific protein test device 430 and the second specific protein test device 440 are the same as those of the blood detector described above, and will not be described here.
[0115] The above is only an embodiment of the present application, and does not limit the patent scope of the present application. Any equivalent structure or equivalent process transformation, or direct or indirect application in other related technical fields, is also included in the patent protection scope of the present application.
Claims
1. A blood testing meter, characterized by, The application relates to a blood sample collection and distribution device, which comprises: a sample collection and distribution device for collecting and distributing a blood sample; a blood routine test device for obtaining the blood sample and testing the blood sample to obtain at least one blood routine parameter; a first specific protein test device comprising at least two first reaction test components for obtaining the blood sample and testing the blood sample to obtain a first specific protein parameter; a second specific protein test device comprising at least one second reaction test component for obtaining the blood sample and testing the blood sample to obtain a second specific protein parameter; a control device for controlling the sample collection and distribution device to collect and distribute the blood sample, controlling the blood routine test device, the first specific protein test device and the second specific protein test device to test respectively, and controlling the sample collection and distribution device to start collecting and distributing the next blood sample before the blood routine test device completes the testing of at least one blood routine parameter of the current blood sample, so that the two first reaction test components exist in time overlap during the testing process; wherein the testing time of the first specific protein test device is greater than the testing time of the second specific protein test device, and the testing time of the first specific protein test device and the testing time of the second specific protein test device are both greater than the testing time of the blood routine test device, and the control device is used for controlling the sample collection and distribution device to distribute the blood sample to the first specific protein test device first, then to the second specific protein test device, and finally to the blood routine test device after the blood sample is collected; wherein the first reaction test component comprises a first detection unit, the second reaction test component comprises a second detection unit, the first detection unit and the second detection unit are the same detection unit, and the detection unit comprises a light source generator and a receiver; the light source generator is used for emitting detection light; the receiver is used for receiving the detection light which passes through the blood sample mixed with a first specific protein test reagent, and / or the receiver is used for receiving the detection light which passes through the blood sample mixed with a second specific protein test reagent; the number of the receivers is multiple, and the multiple receivers are arranged at intervals along the circumference of the light source generator.
2. The blood testing meter of claim 1, wherein, the first reaction test component comprises a first reaction test container, the first reaction test container is used for containing the blood sample and the first specific protein test reagent, so that the blood sample and the first specific protein test reagent can be mixed and reacted in the first reaction test container, and the first detection unit is used for testing the blood sample mixed in the first reaction test container to obtain the first specific protein parameter. The second reaction detection component includes a second reaction detection container for containing the blood sample and the second specific protein detection reagent so that the blood sample and the second specific protein detection reagent can be mixed and reacted in the second reaction detection container, and the second detection unit is used for detecting the mixed blood sample in the second reaction detection container to obtain the second specific protein parameter.
3. The blood testing meter of claim 1, wherein, The first reaction detection component includes a first reaction container and a first detection container, the first reaction container is used for containing the blood sample and the first specific protein detection reagent so that the blood sample and the first specific protein detection reagent can be mixed and reacted in the first reaction container, and the first detection container is used for receiving the mixed blood sample in the first reaction container, and the first detection unit detects the blood sample in the first detection container to obtain the first specific protein parameter. The second reaction detection component includes a second reaction container and a second detection container, the second reaction container is used for containing the blood sample and the second specific protein detection reagent so that the blood sample and the second specific protein detection reagent can be mixed and reacted in the second reaction container, and the second detection container is used for receiving the mixed blood sample in the second reaction container, and the second detection unit detects the blood sample in the second detection container to obtain the second specific protein parameter.
4. The blood testing meter of claim 1, wherein, The detection unit further includes a beam splitter for performing beam splitting processing on the detection light emitted by the light source generator to form a plurality of detection sub-rays, one of the plurality of receivers is used for receiving the detection sub-rays passing through the blood sample mixed with the first specific protein detection reagent, and another of the plurality of receivers is used for receiving the detection sub-rays passing through the blood sample mixed with the second specific protein detection reagent.
5. The blood testing meter of claim 1, wherein, The first detection unit includes a first light source generator for emitting first detection light and a first receiver for receiving the first detection light passing through the blood sample mixed with the first specific protein detection reagent, and the second detection unit includes a second light source generator for emitting second detection light and a second receiver for receiving the second detection light passing through the blood sample mixed with the second specific protein detection reagent.
6. The blood testing meter of claim 1, wherein, The blood routine parameter is a Diff parameter, an HCT parameter, a RET parameter or an NRBC parameter, the first specific protein parameter is a CRP parameter, and the second specific protein parameter is a SAA parameter.
7. A method of blood testing, characterized by, The blood detection instrument is applied to any one of claims 1-6, comprising: controlling the sampling and distributing device to collect a blood sample and distribute the blood sample to a blood routine test device, at least two first reaction test components of a first specific protein test device, and a second reaction test component of a second specific protein test device, respectively; controlling the blood routine test device to test the blood sample to obtain at least one blood routine parameter; controlling the first specific protein test device to test the blood sample to obtain a first specific protein parameter; controlling the second specific protein test device to test the blood sample to obtain a second specific protein parameter; controlling the sampling and distributing device to start collecting and distributing a next blood sample before the blood routine test device completes testing of at least one blood routine parameter of the current blood sample, so that the two first reaction test components have time overlap during the testing process.
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