Traditional Chinese medicine for treating hemorrhoids

Abstract

The invention relates to a Chinese medicine for treating hemorrhoids, which can effectively solve the problem of medication for hemorrhoids. The technical solution is that the Chinese medicine is prepared from the following raw materials by weight: 60-100g of Corydalis yanhusuo, 60-120g of Prunus mume, 150-210g of Astragalus membranaceus, 60-100g of Rubia cordifolia, 60-80g of Angelica dahurica, 50-100g of Saposhnikovia divaricata, 50-100g of Lithospermum officinale, 100-150g of Taraxacum mongolicum, 60-120g of Agrimoniae cyrtonema, 90-150g of Imperatae cylindrica, 30-90g of Magnolia officinalis and 100-150g of Cannabis sativa seed. The Chinese medicine has reasonable formula and rich raw materials. The combination of the medicines can treat the various symptoms of hemorrhoids and achieve the therapeutic effect. Clinical experiments have proved that the Chinese medicine has significant therapeutic effect, short treatment course, quick effect and is not easy to relapse. After clinical application, no obvious adverse reaction is found. The Chinese medicine is an innovation in the medicine for treating hemorrhoids.

Description

1. Technical Field

[0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine for treating hemorrhoids. 2. Background Technology

[0002] Hemorrhoids, also known as hemorrhoids, are soft venous masses formed by the enlargement and varicose veins under the mucosa of the terminal rectum, the anal canal and the skin of the anal margin; or inflammation, hypertrophy and hyperplasia of the connective tissue in the folds of the anal margin; or thrombosis formed by rupture of the anal veins and blood stasis.

[0003] Hemorrhoids are a disease unique to humans. They can occur at any age, but are most common between 20 and 40 years old clinically. The incidence rate gradually increases with age. There is a saying that "nine out of ten men have hemorrhoids" and "ten out of ten women have hemorrhoids". According to the anatomical location and symptoms, they are divided into internal hemorrhoids, external hemorrhoids, and mixed hemorrhoids. The principle of modern medical treatment is mainly surgery, that is, to remove hemorrhoids to eliminate symptoms, but the cost is high, the recurrence rate is high, and it destroys the physiological structure of the anus, causing postoperative complications: anal stenosis, anal fissures, etc. Domestic medications are mostly topical OTC medications, such as Rongchang Antai, Mayinglong Hemorrhoid Cream, etc., which can relieve symptoms of mild hemorrhoids, but the cure rate of moderate to severe patients in children is very low. The pathogenesis of hemorrhoids mainly includes wind, dryness, dampness and heat, and causes the four evils, namely, wind, dryness, dampness and heat. Patients drink a lot of strong liquor, are addicted to spicy food, and suffer from long-term constipation, diarrhea, sitting and standing for a long time, carrying heavy loads for long distances, pregnancy, heredity and other factors, which cause dryness and heat or dampness and heat to be endogenous, and force the large intestine, meridian blockage, and pathogenic heat and blood stasis are stagnant and stagnant. The onset of hemorrhoids often makes patients miserable, with symptoms such as blood in stool, pain, itching, and serious hemorrhoids can also cause perianal eczema, anemia, anal fissure, anal fistula, perianal abscess, hemorrhoid prolapse, incarceration and even necrosis, which has a strong impact on the quality of life of patients. Therefore, it is imperative to invent a Chinese medicine for the treatment of hemorrhoids. III. Summary of the invention

[0004] In view of the above situation, in order to solve the defects of the prior art, the purpose of the present invention is to provide a traditional Chinese medicine for treating hemorrhoids, which can effectively solve the problem of medication for hemorrhoids.

[0005] The technical solution solved by the present invention is that the Chinese medicine is prepared from the following raw materials by weight: 60-100g of Corydalis yanhusuo, 60-120g of Prunus mume, 150-210g of Astragalus membranaceus, 60-100g of Rubia cordifolia, 60-80g of Angelica dahurica, 50-100g of Saposhnikovia divaricata, 50-100g of Lithospermum officinale, 100-150g of Taraxacum mongolicum, 60-120g of Agrimoniae cyrtonema, 90-150g of Imperatae cylindrica, 30-90g of Magnolia officinalis and 100-150g of Cannabis sativa seed, the raw materials are cut into pieces for decoction, mixed together, crushed into fine powder, passed through a 75-mu m pore size sieve, mixed evenly, and 100-120g of refined honey is added to every 100g of powder to prepare large honey pills.

[0006] The invention has a reasonable formula and rich raw materials. The combination of various medicines can treat both the symptoms and the root causes of various symptoms of hemorrhoids and achieve a therapeutic effect. Clinical experiments have proved that the therapeutic effect is significant, the treatment course is short, the effect is fast, and the recurrence is not easy. After clinical application, no obvious adverse reactions are found. The invention is an innovation in the medicine for treating hemorrhoids. 4. Specific implementation methods

[0007] The specific implementation modes of the present invention are further described in detail below in conjunction with the embodiments.

[0008] Example 1

[0009] When the present invention is implemented, it can be prepared from the following raw materials by weight: 60g of Corydalis yanhusuo, 60g of Prunus mume, 150g of Astragalus, 60g of Rubia cordifolia, 60g of Angelica dahurica, 50g of Saposhnikovia divaricata, 50g of Lithospermum officinale, 100g of Taraxacum mongolicum, 60g of Agrimoniae herb, 90g of Imperatae cylindrica, 30g of Magnolia officinalis and 100g of Cannabis sativa seed. The raw materials are cut into pieces and mixed together, crushed into fine powder, sieved through a 75μm pore size sieve, mixed evenly, and 100g of refined honey is used for every 100g of powder to make large honey pills to obtain the product.

[0010] Example 2

[0011] In the specific implementation of the present invention, it can also be made from the following raw materials by weight: 80g of Corydalis yanhusuo, 90g of ebony, 180g of astragalus, 80g of madder, 70g of angelica dahurica, 75g of siler, 75g of lithospermum, 120g of dandelion, 90g of agrimony, 120g of Imperata root, 60g of Magnolia officinalis and 120g of hemp seed. The above raw materials are cut into pieces and mixed together, crushed into fine powder, sieved through a 75μm aperture sieve, mixed evenly, and 110g of refined honey is used for every 100g of powder to make large honey pills.

[0012] Example 3

[0013] When the present invention is implemented, it can also be made from the following raw materials by weight: 100g of Corydalis yanhusuo, 120g of ebony, 210g of astragalus, 100g of madder, 80g of angelica dahurica, 100g of siler, 100g of lithospermum, 150g of dandelion, 120g of agrimony, 150g of Imperatae rhizome, 90g of Magnolia officinalis and 150g of hemp seed. The raw materials are cut into pieces and mixed together, crushed into fine powder, sieved through a 75μm pore size sieve, mixed evenly, and 120g of refined honey is used for every 100g of powder to make large honey pills.

[0014] Among the above drugs,

[0015] Corydalis yanhusuo: Wash, dry and cut into thick slices. It has the functions of promoting blood circulation, promoting qi and relieving pain. It is used for chest and flank pain, abdominal pain, chest obstruction and heart pain, amenorrhea, dysmenorrhea, postpartum stasis, and swelling and pain due to falls.

[0016] Wumei: Wash and dry. It has the functions of astringing the lungs, astringing the intestines, promoting the production of body fluids, and calming ascaris. It is used for chronic cough due to lung deficiency, chronic diarrhea and dysentery, deficiency heat and thirst, ascariasis, vomiting and abdominal pain.

[0017] Astragalus: Wash, moisten thoroughly, cut into thick slices, and dry. It has the effects of replenishing qi and raising yang, consolidating the exterior and stopping sweating, promoting diuresis and reducing swelling, promoting the production of body fluids and nourishing blood, relieving stagnation and relieving arthralgia, expelling toxins and expelling pus, and healing sores and promoting tissue regeneration. It is used for qi deficiency and fatigue, poor appetite and loose stools, sinking of qi in the middle, chronic diarrhea and prolapse of the anus, bloody stool and metrorrhagia, spontaneous sweating due to exterior deficiency, edema due to qi deficiency, internal heat and thirst, sallow complexion due to blood deficiency, hemiplegia, pain and numbness in the arthralgia, carbuncle that is difficult to ulcerate, and carbuncle that does not heal for a long time.

[0018] Rubia cordifolia: Wash, moisten thoroughly, cut into thick slices or segments, and dry. It has the effects of cooling blood, removing blood stasis, stopping bleeding, and regulating menstruation. It is used for hematemesis, epistaxis, metrorrhagia, traumatic bleeding, stasis blocking amenorrhea, joint pain, and swelling and pain caused by falls.

[0019] Angelica dahurica: separate large and small, soak, moisten thoroughly, cut into thick slices, and dry. It has the functions of dispelling cold, dispelling wind and relieving pain, clearing the nasal passages, drying dampness and stopping leukorrhea, and reducing swelling and draining pus. It is used for colds and headaches, pain in the brow bone, nasal congestion and runny nose, allergic rhinitis, sinusitis, toothache, leukorrhea, and sores and swelling.

[0020] Saposhnikovia: Wash, moisten, cut into thick slices, and dry. It has the effects of dispelling wind and relieving exterior symptoms, relieving dampness and relieving pain, and stopping spasms. It is used for colds and headaches, rheumatic pain, urticaria itching, and tetanus.

[0021] Lithospermum officinale: remove impurities and cut into thick slices or segments. It has the effects of clearing heat and cooling blood, promoting blood circulation and detoxifying, and clearing rashes and removing spots. It is used for excessive blood heat and toxicity, purple and black spots, measles that do not clear up, sores, eczema, and burns caused by water or fire.

[0022] Dandelion: Wash and cut into sections. It has the effects of clearing away heat and detoxifying, reducing swelling and dispersing stagnation, and promoting diuresis and relieving stranguria. It is used for carbuncle, breast carbuncle, scrofula, red eyes, sore throat, lung carbuncle, intestinal carbuncle, damp-heat jaundice, and hot stranguria with astringent pain.

[0023] Agrimony: Remove the remaining roots and impurities, wash, moisten slightly, cut into sections, and dry. It has the functions of astringent hemostasis, antimalarial, antidysentery, detoxification, and tonification. It is used for hemoptysis, hematemesis, metrorrhagia, malaria, bloody dysentery, carbuncle, sore, vaginal itching, leucorrhea, and fatigue.

[0024] Imperata root: Wash, moisten slightly, cut into sections, dry and remove debris. It has the effects of cooling blood and stopping bleeding, clearing heat and promoting diuresis. It is used for blood heat, vomiting blood, epistaxis, hematuria, fever, thirst, damp-heat jaundice, edema, oliguria, and painful stranguria caused by heat.

[0025] Magnolia officinalis: scrape off the rough skin, wash, moisten, cut into strips, and dry. It has the effects of drying dampness and eliminating phlegm, and removing qi and fullness. It is used for dampness stagnation, abdominal distension, vomiting and diarrhea, food accumulation and qi stagnation, abdominal distension and constipation, phlegm and cough.

[0026] Hemp seed: Fry hemp seed until it turns slightly yellow and has an aroma. It has the effect of moistening the intestines and relieving constipation. It is used for blood deficiency, body fluid deficiency, dry intestines and constipation.

[0027] The invention is prepared by crushing common Chinese medicine by micro-powder technology, adding refined honey to make pills, and in the formula, Corydalis yanhusuo is used as the main medicine, which can relieve and treat the pain of hemorrhoids by promoting blood circulation, promoting qi and relieving pain, and taking black plum and astragalus as the assistant medicine, which can replenish qi and consolidate the body, promote body fluid and astringe the intestines for the symptoms of prolapse of hemorrhoids; taking dandelion and Imperata root as the adjuvant medicine, which can detoxify and reduce swelling for perianal abscess, and taking hemp seed as the guiding medicine, which can moisten the intestines and relieve constipation. The combination of the medicines can treat both the symptoms and the root causes of various symptoms of hemorrhoids, achieve the therapeutic effect, and clinical experiments have proved that the efficacy is remarkable, the treatment course is short, the effect is fast, and it is not easy to relapse. The relevant clinical data are as follows:

[0028] 1. Case selection

[0029] All outpatient patients who report symptoms such as blood in the stool, anal prolapse, perianal swelling, pain, itching, and dampness can be selected as cases.

[0030] 2. Diagnostic Criteria

[0031] 1. Blood in stool: Toilet paper is stained with blood during defecation, and there may be spotting or spurting bleeding.

[0032] 2. Prolapse: Hemorrhoids prolapse, the prolapsed material is bright red or grayish white in color. If the sodium is not replaced in time, local swelling may worsen.

[0033] 3. The area around the anus is moist, itchy, and the secretions increase.

[0034] 4. Pain: Anal swelling, pain, and heaviness. Prolapsed internal hemorrhoids become incarcerated, causing edema, thrombosis, necrosis, and severe pain.

[0035] 5. Constipation: long-term constipation or habitual constipation.

[0036] Anyone who has more than one of the above items can be diagnosed with this disease.

[0037] 3. Exclusion criteria:

[0038] 1. Exclude anal bleeding caused by digestive tract diseases and rectal cancer;

[0039] 2. Women who are pregnant, breastfeeding or planning to become pregnant;

[0040] 3. People with allergic constitution or allergic to the ingredients of this drug;

[0041] 4. Patients with severe primary diseases such as cardiovascular, cerebrovascular, liver, kidney, and hematopoietic system diseases, as well as mental illness.

[0042] IV. Treatment Plan

[0043] The patient takes 1 pill each time, 3 times a day, and 7 days is a course of treatment. After taking a course of treatment, the efficacy is checked, and a control group is set for control treatment comparison. The large honey pills prepared in Example 2 of the present invention are group A, and the commercially available Foci Xiaozhi Pills are group B for comparison.

[0044] V. Evaluation Criteria for Syndrome Efficacy

[0045] 1. Clinical recovery: symptoms and signs disappear or almost disappear, and syndrome score decreases by ≥95%.

[0046] 2. Marked effect: symptoms and signs are significantly improved, and the syndrome score is reduced by ≥70%.

[0047] 3. Effective: Symptoms and signs are improved, and the syndrome score is reduced by ≥30%.

[0048] 4. Ineffective: Symptoms and signs have no significant improvement, or even worsen, and the symptom score decreases by less than 30%. The calculation formula (nimodipine method) is: [(score before treatment - score after treatment) ÷ score before treatment] × 100%.

[0049] 6. Statistical Processing

[0050] After a comparative treatment of 128 hemorrhoid patients, they were randomly divided into two groups, 66 in group A and 62 in group B. After taking the treatment plan for one week, the results of the efficacy were as follows:

[0051] Table 1 Comparison of clinical efficacy of drugs A and B

[0052] drug Case get well Significant effect efficient invalid Total effective rate (%) A 66 32 26 6 2 97.0％ B 62 18 11 18 15 75.8％

[0053] In terms of clinical efficacy, drug A was significantly better than drug B (P < 0.01).

[0054] Table 2 Comparison of the efficacy of drugs A and B in major clinical symptoms

[0055]

[0056] Group A was also superior to Group B in terms of the efficacy of major clinical symptoms.

[0057] After repeated experiments, the products made from other embodiments of the present invention can achieve the same or similar beneficial effects as the above experimental results.

[0058] VII. Conclusion

[0059] In summary, the present invention has reasonable compatibility and rich drug sources. The drug formulation of the present invention is superior to Xiaozhi Pills in clinical efficacy, and the process is also relatively simple. After being crushed into micropowder, refined honey is added to make pills, and the pills can be taken. The drug has significant efficacy, no side effects, and high safety. After clinical application, no obvious adverse reactions were found. The drug can be effectively used to treat hemorrhoids, has broad market prospects, and will generate huge economic and social benefits after expanding production.

[0060] It should be pointed out that the above is only a preferred embodiment of the present invention and does not limit the present invention in any form. Any technician familiar with the profession can make changes or modify the technical contents disclosed above into equivalent embodiments with equivalent changes without departing from the scope of the technical solution of the present invention, which all fall within the protection scope of the present invention.

Claims

1. A Chinese medicine for treating hemorrhoids, characterized in that: The Chinese medicine is prepared from the following raw materials by weight: 60-100g of Corydalis yanhusuo, 60-120g of Prunus mume, 150-210g of Astragalus membranaceus, 60-100g of Rubia cordifolia, 60-80g of Angelica dahurica, 50-100g of Saposhnikovia divaricata, 50-100g of Lithospermum officinale, 100-150g of Taraxacum mongolicum, 60-120g of Agrimoniae cyrtonema, 90-150g of Imperatae cylindrica, 30-90g of Magnolia officinalis and 100-150g of Cannabis sativa seed. The raw materials are cut into pieces and mixed together, crushed into fine powder, passed through a 75-mu m pore size sieve, mixed evenly, and 100-120g of refined honey is added to every 100g of powder to prepare large honey pills.

2. The Chinese medicine for treating hemorrhoids according to claim 1, characterized in that, It is made from the following raw materials by weight: 60g of Corydalis yanhusuo, 60g of ebony, 150g of astragalus, 60g of madder, 60g of angelica dahurica, 50g of siler, 50g of lithospermum, 100g of dandelion, 60g of agrimony, 90g of Imperatae rhizome, 30g of Magnolia officinalis and 100g of hemp seed. The above raw materials are cut into pieces and mixed together, crushed into fine powder, sieved through a 75μm pore size, mixed evenly, and 100g of refined honey is used for every 100g of powder to make large honey pills.

3. The Chinese medicine for treating hemorrhoids according to claim 1, characterized in that, The drug is prepared from the following raw materials by weight: 80g of Corydalis yanhusuo, 90g of ebony, 180g of astragalus, 80g of madder, 70g of angelica dahurica, 75g of siler, 75g of lithospermum, 120g of dandelion, 90g of herbaceous agrimony, 120g of imperata root, 60g of magnolia bark and 120g of canna seed. The raw materials are cut into pieces and mixed together, crushed into fine powder, sieved through a 75μm pore size sieve, mixed evenly, and 110g of refined honey is used for every 100g of powder to make large honey pills.

4. The Chinese medicine for treating hemorrhoids according to claim 1, characterized in that, The drug is prepared from the following raw materials by weight: 100g of Corydalis yanhusuo, 120g of ebony, 210g of astragalus, 100g of madder, 80g of angelica dahurica, 100g of siler, 100g of lithospermum, 150g of dandelion, 120g of agrimony, 150g of imperata root, 90g of magnolia bark and 150g of canna seed. The raw materials are cut into pieces and mixed together, crushed into fine powder, sieved through a 75μm pore size sieve, mixed evenly, and 120g of refined honey is used for every 100g of powder to make large honey pills.

Images