Insecticidal composition containing fluoropyrafuranone and isoxathiapiprolin

Abstract

The present invention relates to the field of insecticide technology and provides an insecticidal composition containing fluopyrone and isoxathiapiprolin. The active ingredients of the insecticidal composition include isoxathiapiprolin and fluopyrone. This technical solution solves the problem of high application amounts of active ingredients and poor effectiveness in insecticidal compositions in related technologies.

Description

Technical Field

[0001] The present invention relates to the technical field of insecticides, and in particular to an insecticidal composition containing fluoropyraclostrobin and isoxathiapiprolin. Background Art

[0002] Piercing-sucking pests are a type of insect that severely damages crops and plants. They typically use their sharp mouthparts to pierce plant stems, leaves, and fruits, sucking sap. This behavior can damage plant tissues, causing various brown spots, and impairing photosynthesis and normal growth. For example, aphids and whiteflies, while feeding on plant sap, also secrete honeydew, which coats plant leaves, causing sooty mold and further impairing photosynthesis. Therefore, the control of aphids and whiteflies has always been a major concern.

[0003] Traditional nicotinoid pesticides are effective against aphids and whiteflies, but long-term use has led to significant resistance in these pests. Flupyralid, a new nicotinoid insecticide, is applicable to a wide range of crops and has a broad control spectrum. It can selectively control piercing-sucking pests, effective against both larvae and adults. Isoxafenamide has good control effects against pests in the Lepidoptera, Hemiptera, Thysanoptera, and Acarina orders, and its production and use costs are relatively low. Isoxafenamide can provide long-term pest control at extremely low doses and is not easily dissolved or drifted in the soil, providing precise and effective pest control in the root zone of crops. Although both flupyralid and isoxafenamide have certain control effects against pests such as aphids and whiteflies, long-term use of a single insecticide can lead to insecticide resistance in pests, reducing the effectiveness of the insecticide. Currently, there are no reports on the combination of flupyralid and isoxafenamide. Therefore, developing a multi-component insecticide composition to improve the effectiveness of insecticides is a problem that needs to be solved at present. Summary of the Invention

[0004] The present invention provides an insecticidal composition containing fluoropyraclostrobin and isoxathiapiprolin, which solves the problem of high application amount of active ingredients and poor effectiveness of the insecticidal composition in the related art.

[0005] The technical solutions of the present invention are as follows:

[0006] The present invention provides an insecticidal composition containing fluopyrone and isoxathiapiprolin. The insecticidal composition comprises an active ingredient A and an active ingredient B, wherein the active ingredient A is isoxathiapiprolin and the active ingredient B is fluopyrone.

[0007] As a further technical solution, the mass ratio of the active ingredient A to the active ingredient B is 0.02~50:1.

[0008] As a further technical solution, the total weight of the insecticide composition is 100 wt%, and the total weight of the active ingredient A and the active ingredient B in the insecticide composition is 1 wt% to 90 wt% of the total weight of the insecticide composition.

[0009] As a further technical solution, the total mass of the active ingredient A and the active ingredient B in the insecticidal composition is 15 wt% to 40 wt% of the total mass of the insecticidal composition.

[0010] As a further technical solution, the insecticide composition can be prepared into an agriculturally acceptable formulation.

[0011] As a further technical solution, the acceptable formulations include water-dispersible granules, wettable powders, aqueous emulsions, dispersible oil suspensions, and suspensions.

[0012] As a further technical solution, the insecticide composition further comprises one or more of the following components: a dispersant, an emulsifier, an antifreeze agent, a thickener, a defoaming agent, a wetting agent, a disintegrant, a filler, and a solvent.

[0013] As a further technical solution, the dispersant includes one or more of calcium lignin sulfonate, sodium diisobutylnaphthalene sulfonate, sodium isopropylnaphthalene sulfonate, and sodium naphthalenesulfonic acid formaldehyde condensate.

[0014] As a further technical solution, the emulsifier includes one or more of tristyryl polyoxyethylene polyoxypropylene ether, dibenzyl biphenyl polyoxyethylene ether, polyoxyethylene stearate, fatty alcohol polyoxyethylene ether phosphate, and nonionic fatty alcohol EO / PO block copolymer.

[0015] As a further technical solution, the thickener includes one or more of alkoxylated butyl ether block copolymers, xanthan gum, polyacrylate, and polyvinyl alcohol.

[0016] As a further technical solution, the antifreeze agent includes one or more of ethylene glycol, glycerol, and polyethylene glycol.

[0017] As a further technical solution, the defoaming agent includes one or more of diethylhexanol, ethylene glycol monostearate, and distearylethylenediamine.

[0018] As a further technical solution, the wetting agent includes one or more of sodium lignin sulfonate, sodium salt of alkylnaphthalenesulfonic acid condensate, sodium dodecyl sulfonate, sodium dodecyl sulfate, and polycarboxylates; the disintegrant includes one or more of ammonium sulfate, sodium chloride, sodium carboxymethyl starch, sodium alginate, and urea; the filler includes one or more of white carbon black, kaolin, diatomaceous earth, diatomaceous earth, and bentonite; and the solvent is one or more of cyclohexanone, dimethylformamide, methyl oleate, N-methylpyrrolidone, and water.

[0019] The present invention also provides an application of an insecticide composition containing fluoropyraclostrobin and isoxathiapiprole in preventing and controlling herbivorous pests in agriculture, forestry or gardening.

[0020] As a further technical solution, the herbivorous pests are piercing-sucking pests.

[0021] As a further technical solution, the piercing-sucking pests include aphids and whiteflies.

[0022] As a further technical solution, the insecticide composition is applied to the pests to be controlled or the medium in which they grow at an effective dose, and the effective dose is 40-80 g per hectare.

[0023] The working principle and beneficial effects of the present invention are:

[0024] In the present invention, by compounding flupyralid and isoxathiapiprolin, a synergistic effect is achieved, pests can be controlled more effectively, and the amount of insecticide used can be reduced. Through a combined toxicity assay experiment, the insecticidal composition using flupyralid and isoxathiapiprolin as active ingredients has a good control effect on aphids and whiteflies, solves the problem of a large amount of active ingredient application, reduces environmental pollution, and delays the development of insecticide resistance in pests. DETAILED DESCRIPTION

[0025] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making any creative efforts are within the scope of protection of the present invention.

[0026] In the following embodiments:

[0027] Alkoxylated butyl ether block copolymer, brand: Ethylan NS-500LQ, nonionic fatty alcohol EO / PO block copolymer representative brand: Ethylan 992, both purchased from Nouryon;

[0028] Organic bentonite, product number: YJ01, was purchased from Anji Tianhong Bentonite Co., Ltd.

[0029] Example 1

[0030] 20% flupyralidone and isoxathiapiprolin wettable powder:

[0031] 12% flupyralid, 8% isoxathiapiprolin, 5% calcium lignin sulfonate, 3% sodium lauryl sulfate, and diatomaceous earth are added to make up to 100%, and then air flow milling is performed to prepare 20% flupyralid and isoxathiapiprolin wettable powder.

[0032] Example 2

[0033] 40% flupyralidone and isoxathiapiprolin wettable powder:

[0034] 20% flupyralid, 20% isoxathiapiprolin, 4% sodium diisobutylnaphthalene sulfonate, 5% sodium lignin sulfonate, 5% white carbon black, and kaolin are added to 100%, mixed and then air flow milled to prepare 40% flupyralid and isoxathiapiprolin wettable powder.

[0035] Example 3

[0036] 30% flupyralidone and isoxathiapiprolin water dispersible granules:

[0037] 5% flupyralid, 25% isoxathiapiprolin, 6% sodium salt of alkylnaphthalenesulfonic acid polycondensate, 3% sodium isopropylnaphthalenesulfonate, 20% ammonium sulfate, and bentonite are added to make up to 100%, and the mixture is mixed and granulated to prepare 30% flupyralid and isoxathiapiprolin water dispersible granules.

[0038] Example 4

[0039] 25% flupyralidone and isoxathiapiprolin suspension concentrate:

[0040] 10% flupyralid, 15% isoxathiapiprolin, 4% sodium naphthalenesulfonic acid formaldehyde condensate, 2% polycarboxylate, 1% xanthan gum, 2% urea, and water are added to 100%, mixed and sand-milled to prepare a 25% flupyralid and isoxathiapiprolin aqueous suspension.

[0041] Example 5

[0042] 20% flupyralidone and isoxathiapiprolin emulsion in water:

[0043] 10% fluopyrone, 10% isoxathiapiprolin, 20% cyclohexanone, 1% propylene glycol, 10% tristyryl polyoxyethylene polyoxypropylene ether, 10% fatty alcohol polyoxyethylene ether phosphate, and water to 100% are mixed by high shear emulsification to prepare a 20% fluopyrone and isoxathiapiprolin aqueous emulsion.

[0044] Example 6

[0045] 15% flupyralidone and isoxathiapiprolin dispersible oil suspension concentrate:

[0046] 10% flupyralid, 5% isoxathiapiprolin, 5% alkoxylated butyl ether block copolymer, 5% nonionic fatty alcohol EO / PO block copolymer, 3% organic bentonite, and methyl oleate are added to 100%, mixed and sand-milled to prepare a 15% flupyralid and isoxathiapiprolin dispersible oil suspension concentrate.

[0047] Experiment 1. Combined toxicity assay

[0048] The combined toxicity of flupyralid and isoxathiapiprolin mixtures was determined using the co-toxicity coefficient method. Flupyralid and isoxathiapiprolin mixtures were prepared in ratios of 50:1, 25:1, 10:1, 5:1, 1:1, 1:5, 1:10, 1:25, and 1:50. The agents were weighed according to the above mass ratios, thoroughly dissolved in acetone, and then diluted with water to the various test concentrations. The toxicity of the mixtures against aphids and whiteflies was determined using the insect and leaf immersion method. The results are shown in Table 1.

[0049] Table 1 Toxicity test results of mixed pesticides against aphids and whiteflies

[0050]

[0051] According to the combined toxicity calculation method, if the CTC of a compound formulation is between 80 and 120, it indicates an additive effect; if the CTC is greater than 120, it indicates a synergistic effect; and if the CTC is less than 80, it indicates an antagonistic effect. As shown in Table 1, the co-toxicity coefficient (CTC) of flupyralid and isoxathiapyr in a mass ratio of 0.02 to 50:1 against aphids and whiteflies is greater than 120, indicating that flupyralid and isoxathiapyr have a good synergistic effect when mixed in a mass ratio of 0.02 to 50:1.

[0052] Experiment 2: Field control effect of flupyralid and isoxathiapyr (1:1) on cucumber aphids

[0053] (1) Experimental setting: set up 1 experimental group and 2 control groups

[0054] Experimental group: flupyralid and isoxathiapiprolin (1:1), i.e., flupyralid and isoxathiapiprolin 20% in Example 5;

[0055] Control group 1: Emulsion in water containing only isoxathiapiprolin at a mass fraction of 20%;

[0056] Control group 2: an aqueous emulsion containing only flupyralidone at a mass fraction of 20%.

[0057] (2) Experimental method: Using a backpack sprayer, the entire plant in each experimental plot was uniformly sprayed according to the designed test dosage. Before spraying, samples were collected at 5 points in each plot. 10 to 20 cucumber plants were continuously inspected at each point and marked (total number of plants). The number of adult and nymph aphids on each cucumber plant was investigated and recorded. The number of remaining aphids was investigated on the first, third, and seventh day after spraying.

[0058] (3) Statistics of experimental results

[0059] The insect population reduction rate and control effect were calculated according to the following formula:

[0060]

[0061] The calculation results are shown in Table 2.

[0062] Table 2 The field control effects of flupyralid and isoxathiapiprolin against aphids

[0063]

[0064] As can be seen from the table, compared with the isoxathiapyr of control group 1 and the flupyronil of control group 2, the isoxathiapyr:flupyronil (1:1) of the experimental group had significantly improved control effects on aphids at the test dose, and the control effect increased with the increase of the dose, indicating that the control effect of the insecticidal composition of isoxathiapyr and flupyronil on cucumber aphids was significantly better than that of the single agents of isoxathiapyr and flupyronil.

[0065] Experiment 3: Field control effect of flupyralid and isoxathiapyr (2:3) on tomato whitefly

[0066] (1) Experimental setting: set up 1 experimental group and 2 control groups

[0067] Experimental group: flupyrazone and isoxathiapiprolin (2:3), i.e., flupyrazone and isoxathiapiprolin 25% in Example 4;

[0068] Control group 1: Emulsion in water containing only isoxathiapiprolin at a mass fraction of 25%;

[0069] Control group 2: aqueous emulsion containing only flupyralidone at a mass fraction of 25%.

[0070] (2) Experimental method: Using a knapsack sprayer, the entire plant in each experimental plot was uniformly sprayed according to the designed test dosage. Before spraying, samples were collected at 5 points in each plot. 10 to 20 tomato plants were continuously inspected at each point and marked (total number of plants). The number of adult and nymph whiteflies on each tomato plant was investigated and recorded. The number of remaining whiteflies was investigated on the 1st, 3rd, 5th, 7th, and 10th day after spraying.

[0071] (3) Experimental results: The calculation formula is the same as that of Experiment 2. The calculation results are shown in Table 3.

[0072] Table 3 Control effects of flupyralid and isoxathiapiprolin against whiteflies in the field

[0073]

[0074] As can be seen from the above table, compared with the isoxathiapyr of control group 1 and the flupyronil of control group 2, the isoxathiapyr:flupyronil (3:2) of the experimental group had significantly improved control effect on whiteflies at the test dose, and the control effect increased with the increase of dose, indicating that the control effect of the insecticide composition of isoxathiapyr and flupyronil on tomato whiteflies was significantly better than that of the single agents of isoxathiapyr and flupyronil.

[0075] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. An insecticidal composition containing fluoropyrafuranone and isoxathiapiprolin, characterized in that: The invention comprises active ingredient A and active ingredient B, wherein the active ingredient A is isoxathiapyr and the active ingredient B is flupyradone; and the mass ratio of the active ingredient A to the active ingredient B is 0.02-50:

1.

2. The insecticidal composition containing fluoropyraclostrobin and isoxathiapiprolin according to claim 1, characterized in that: The total weight of the insecticide composition is 100 wt %, and the total weight of the active ingredient A and the active ingredient B in the insecticide composition is 1 wt % to 90 wt % of the total weight of the insecticide composition.

3. The insecticidal composition containing fluoropyrafuranone and isoxathiapiprolin according to claim 2, characterized in that: The insecticide composition can be prepared into an agriculturally acceptable formulation.

4. The insecticidal composition containing fluoropyraclostrobin and isoxathiapiprolin according to claim 3, characterized in that: The acceptable formulations are water-dispersible granules, wettable powders, aqueous emulsions, dispersible oil suspensions, and suspensions.

5. The insecticidal composition containing fluoropyraclostrobin and isoxathiapiprolin according to claim 4, further comprising one or more of the following components: a dispersant, an emulsifier, an antifreeze agent, a thickener, a defoaming agent, a wetting agent, a disintegrant, a filler, and a solvent.

6. Use of an insecticidal composition containing fluoropyrafuranone and isoxathiapiprole according to any one of claims 1 to 5 in controlling herbivorous pests in agriculture, forestry or gardening; The herbivorous pests are piercing-sucking pests; The piercing-sucking pests include aphids and whiteflies.

7. The use of an insecticidal composition containing fluoropyrafuranone and isoxathiapiprole according to claim 6, characterized in that: The insecticide composition is applied to the pests to be controlled or the medium where they grow at an effective dose of 40 to 80 g per hectare.

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