Oral spray essence

Abstract

The invention discloses oral spray essence, and relates to the technical field of oral spray essence. The oral spray essence is prepared from the following raw materials in parts by weight: 0.5 to 15 parts of humectants, 0.1 to 5 parts of surfactants, 0.1 to 10 parts of taste modifiers, 0.1 to 1 part of essence, 0.1 to 3 parts of pH buffer agents, 0.01 to 0.5 part of bacteriostatic agents, 0.1 to 2 parts of preservatives, 0.1 to 5 parts of probiotics, 0.1 to 5 parts of sodium hyaluronate, 0.1 to 5 parts of extracts and 58.5 to 98.89 parts of water, the chewable tablet is prepared from xylitol, erythritol, trichlorogalactose, menthol, cane sugar, saccharin, saccharin sodium, xylitol, sorbitol, menthol, maltitol, lactitol, psicose, mannitol, isomaltitol, isomaltooligosaccharide, sodium cyclamate, aspartame, acesulfame potassium, sucralose, trichlorogalactose, stevioside and thaumatin. And one or more of ammonium glycyrrhizinate is used as the taste improver, so that the taste of the oral spray can be improved, the bad taste of some components in the oral spray is covered, and the oral spray is endowed with fresh and lasting taste and style.

Description

Technical Field

[0001] The invention relates to the technical field of oral spray essence, in particular to an oral spray essence. Background Art

[0002] The working principle of mouth spray, in simple terms, is called "physical masking", that is, using a stronger flavor to cover up the original breath smell, while adding cooling ingredients to make people feel refreshed, thereby achieving the purpose of freshness. Some mouth sprays also have antibacterial and anti-inflammatory effects, but the effects are very small, because the amount of mouth spray taken each time is very small, so it is difficult to play a good antibacterial and anti-inflammatory role, so it is mainly necessary to do a good job of oral cleaning in the morning and evening; The principle of mouth spray is not difficult to explain, but it is not easy to do well. The experience of mouth spray can be judged from two perspectives: natural fragrance + freshness and persistence. The natural fragrance refers to whether the fragrance of the mouth spray (such as mint, lime, orange, etc.) is natural enough and no trace of artificial synthesis can be felt. To make a natural fragrance, it is necessary to control the quality of raw materials and the level of perfumers. At the same time, a certain scale of black box testing of people is also required to determine a fragrance with the widest audience. Freshness and persistence refers to how long you can feel the coolness after using the mouth spray. To a certain extent, the natural fragrance and freshness and persistence will increase and decrease. If the naturalness is improved, the persistence needs to be compromised. If the persistence is extended, the taste will not be so good. Therefore, a good mouth spray must be continuously tested and optimized, and the formula ratio must be continuously adjusted to meet the evolving consumer taste preferences. In order to achieve a balance between the natural fragrance, freshness and persistence of the oral spray essence and the bactericidal and anti-inflammatory effects, the present invention provides an oral spray essence for solving the above problems. Summary of the invention

[0003] The technical problem to be solved by the present invention is to overcome the problem of unbalanced efficacy of oral spray essence and provide an oral spray essence to solve the above problem.

[0004] To achieve the above-mentioned purpose, the present invention provides the following technical scheme: an oral spray essence, which comprises the following raw materials in parts by weight: 0.5-15 parts of moisturizing agent, 0.1-5 parts of surfactant, 0.1-10 parts of taste improver, 0.1-1 parts of flavor, 0.1-3 parts of pH buffer, 0.01-0.5 parts of antibacterial agent, 0.1-2 parts of preservative, 0.1-5 parts of probiotics, 0.1-5 parts of sodium hyaluronate, 0.1-5 parts of extract, and 58.5-98.89 parts of water.

[0005] Furthermore, the oral spray essence includes the following raw materials in parts by weight: 10 parts of moisturizer, 2 parts of surfactant, 5 parts of taste improver, 0.5 parts of flavor, 1.5 parts of pH buffer, 0.3 parts of antibacterial agent, 1 part of preservative, 2 parts of probiotics, 2 parts of sodium hyaluronate, 3 parts of extract and 70 parts of water.

[0006] Furthermore, the extract is one or more of cherry blossom extract, grape seed extract, honeysuckle extract, mint extract, lemon fruit extract, tea polyphenols, watermelon fruit extract, essence and sea salt.

[0007] Furthermore, the taste improver is one or more of xylitol, erythritol, sucralose, menthol, sucrose, saccharin, saccharin sodium, xylitol, sorbitol, menthol, maltitol, lactitol, allulose, mannitol, isomalt, oligoisomaltitol, cyclamate, aspartame, acesulfame potassium, sucralose, sucralose, stevioside, thaumatin, and ammonium glycyrrhizinate.

[0008] Furthermore, the antibacterial agent is one or more of cetylpyridinium chloride, domiphene, o-cymene-5-ol, chlorhexidine gluconate, benzethonium chloride, and lysozyme.

[0009] Furthermore, the probiotics are one or more of lactobacillus, Lactobacillus paracasei, Lactobacillus plantarum, lactobacillus lysate fermentation product, Lactobacillus acidophilus, Lactobacillus reuteri, Lactobacillus casei, Bifidobacterium lactis, and Lactobacillus salivarius.

[0010] Furthermore, the pH buffer is one or more of citric acid, sodium citrate, potassium citrate, sodium lactate, lactic acid, potassium hydroxide, sodium hydroxide, disodium hydrogen phosphate, triethanolamine, and arginine.

[0011] Furthermore, the surfactant is one or more of poloxamer 407, polysorbate-80, polysorbate-20, polyglycerol-4 oleate, PEG-20 hydrogenated castor oil, PEG-40 hydrogenated castor oil, lecithin, poloxamer 188, and poloxamer 184.

[0012] Furthermore, the preservative is one or more of p-hydroxyacetophenone, caprylhydroxamic acid, monocaprylic glyceryl, phenoxyethanol, sodium benzoate, potassium sorbate, parabens, and phenoxyethanol.

[0013] Furthermore, the moisturizing agent is one or more of glycerol, PEG-400, 1,3-propylene glycol, 1,3-butylene glycol, 1,2-hexanediol, 1,2-pentanediol, ethoxydiglycol, and caprylyl glycol.

[0014] Compared with the prior art, the present invention has the following beneficial effects: 1. The oral spray essence of the present invention uses one or more of xylitol, erythritol, galactose, menthol, sucrose, saccharin, saccharin sodium, xylitol, sorbitol, menthol, maltitol, lactitol, allulose, mannitol, isomalt, oligoisomaltitol, sodium cyclamate, aspartame, acesulfame potassium, sucralose, galactose, steviol glycoside, thaumatin, and ammonium glycyrrhizinate as taste improvers, which can improve the taste of the oral spray, cover up the bad taste of some ingredients in the oral spray, and give the oral spray a fresh and lasting taste and style; 2. The oral spray essence of the present invention is supplemented with one or more extracts of various cherry blossom extracts, grape seed extracts, honeysuckle extracts, mint extracts, lemon fruit extracts, tea polyphenols, watermelon fruit extracts, essences and sea salt to form a blended complex flavor. Under the action of a surfactant, a suspension liquid mixture with a stable system, complex ingredients and uniform distribution is formed, which can provide multiple flavors to choose from, and the fragrance is fresh and natural, refreshing; 3. The oral spray essence of the present invention contains one or more of cetylpyridinium chloride, domiphene, o-cymene-5-ol, chlorhexidine gluconate, benzethonium chloride, and lysozyme as antibacterial agents, is green and environmentally friendly, safe and non-toxic, has no residue, has no side effects, does not produce drug resistance, can instantly and effectively remove and purify odors and bad smells, and is added with one or more of lactobacillus, Lactobacillus paracasei, Lactobacillus plantarum, lactobacillus lysate fermentation products, Lactobacillus acidophilus, Lactobacillus reuteri, Lactobacillus casei, Bifidobacterium lactis, and Lactobacillus salivarius as beneficial bacteria, which is beneficial to protecting the health of the oral cavity and the stomach, does not contain broad-spectrum antibacterial agents and alcohol, is mild and non-irritating, and is refreshing and non-irritating to the mouth. It can not only softly clean the oral cavity, provide a good growth environment for beneficial bacteria, but also refresh the breath. Implementation

[0015] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention. Example

[0016] The present embodiment is a cherry grape oral spray essence, which includes the following raw materials in parts by weight: water, glycerin, PEG-40 hydrogenated castor oil, poloxamer 407, xylitol, erythritol, p-hydroxyacetophenone, 1,2-hexanediol, sodium hyaluronate, cherry blossom flower extract, essence, sodium citrate, menthol, domiphene, cypermethrinium chloride, citric acid, and trichlorogalactose. Example

[0017] The present embodiment is a fleshy grape oral spray essence, which includes the following raw materials in parts by weight: water, glycerin, PEG-40 hydrogenated castor oil, poloxamer 407, xylitol, erythritol, p-hydroxyacetophenone, 1,2-hexanediol, sodium hyaluronate, lactobacillus, grape seed extract, sodium citrate, menthol, sea salt, honeysuckle extract, essence, domiphene, arsenicum chloride, citric acid, and trichlorogalactose. Example

[0018] The present embodiment is a breath of ocean oral spray essence, which includes the following raw materials in parts by weight: water, glycerin, PEG-40 hydrogenated castor oil, poloxamer 407, xylitol, erythritol, p-hydroxyacetophenone, 1,2-hexanediol, sodium hyaluronate, mint extract, sodium citrate, lactobacillus, flavor, menthol, domiphene, cypermethrinium chloride, citric acid, and trichlorogalactose. Example

[0019] The present embodiment is a northern cedar oral spray essence, which includes the following raw materials in parts by weight: water, glycerin, PEG-40 hydrogenated castor oil, poloxamer 407, xylitol, erythritol, p-hydroxyacetophenone, 1,2-hexanediol, sodium hyaluronate, honeysuckle extract, sodium citrate, lactobacillus, essence, menthol, domiphene, cypermethrinium chloride, citric acid, and trichlorogalactose. Example

[0020] The present embodiment is a sea salt and lime oral spray essence, which includes the following raw materials in parts by weight: water, glycerin, PEG-40 hydrogenated castor oil, poloxamer 407, xylitol, erythritol, p-hydroxyacetophenone, 1,2-hexanediol, sodium hyaluronate, lactobacillus, sodium citrate, menthol, lemon fruit extract, sea salt, essence, domiphene, citric acid, and trichlorogalactose. Example

[0021] The present embodiment is a peach black tea oral spray essence, which includes the following raw materials in parts by weight: water, glycerin, PEG-40 hydrogenated castor oil, poloxamer 407, xylitol, erythritol, p-hydroxyacetophenone, 1,2-hexanediol, sodium hyaluronate, tea phenol, sodium citrate, menthol, lactobacillus, essence, domiphene, citric acid, and trichlorogalactose. Example

[0022] The present embodiment is an iced watermelon oral spray essence, which includes the following raw materials in parts by weight: water, glycerin, PEG-40 hydrogenated castor oil, poloxamer 407, xylitol, erythritol, p-hydroxyacetophenone, 1,2-hexanediol, sodium hyaluronate, lactobacillus, watermelon fruit extract, essence, sodium citrate, menthol, domiphene, citric acid, and trichlorogalactose.

[0023] The oral spray essences prepared in Examples 1 to 7 were subjected to acute oral toxicity tests on 7 groups of rats in the control group, as follows: Testing environment: barrier environment animal room, room temperature 22+2°C, humidity 62+5%; Experimental animals and feeds in each group: 20 SPF-grade SD rats (10 females and 10 males), weighing 1800 g-2000 g; Sample preparation: Weigh 100.0 g of sample and add ultrapure water to mix to 200 mL as the test solution; Test steps: The formal test adopts the limit method, the test substance dose is set at 10000 mg / kg body weight, and the test solution is administered once orally through the stomach with a gavage needle at a volume of 2.0 mL / 100 g body weight. The animals are fasted for 16 hours before gavage and have free access to water. They are given a normal diet 3 hours after gavage. Observation: The experiment was observed for 14 days, and the poisoning symptoms and deaths were recorded. The living animals were weighed once a week during the observation period. At the end of the observation period, the surviving animals were humanely killed and autopsied. Results: During the observation period, no obvious poisoning symptoms or death were observed in all the test animals, and no abnormalities were found in the gross anatomy of the experimental animals. Therefore, the acute oral toxicity LD50 of rats was > 10000 mg / kg body weight; Test conclusion: The acute oral toxicity LDS of the oral spray essence prepared in Examples 1 to 7 is > 10000 mg / kg body weight, which is a practically non-toxic substance according to the acute toxicity (LDSo) dose grading table of GB15193.3-2014 "National Food Safety Standard Acute Oral Toxicity Test".

[0024] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An oral spray essence, It is characterized in that The oral spray essence comprises the following raw materials in parts by weight: 0.5-15 parts of moisturizer, 0.1-5 parts of surfactant, 0.1-10 parts of taste improver, 0.1-1 parts of flavor, 0.1-3 parts of pH buffer, 0.01-0.5 parts of antibacterial agent, 0.1-2 parts of preservative, 0.1-5 parts of probiotics, 0.1-5 parts of sodium hyaluronate, 0.1-5 parts of extract, and 58.5-98.89 parts of water.

2. The oral spray essence according to claim 1, It is characterized in that The oral spray essence comprises the following raw materials in parts by weight: 10 parts of moisturizer, 2 parts of surfactant, 5 parts of taste improver, 0.5 parts of flavor, 1.5 parts of pH buffer, 0.3 parts of antibacterial agent, 1 part of preservative, 2 parts of probiotics, 2 parts of sodium hyaluronate, 3 parts of extract and 70 parts of water.

3. The oral spray essence according to claim 1, It is characterized in that The extract is one or more of cherry blossom extract, grape seed extract, honeysuckle extract, mint extract, lemon fruit extract, tea polyphenols, watermelon fruit extract, essence and sea salt.

4. The oral spray essence according to claim 1, Features: The taste improver is one or more of xylitol, erythritol, sucralose, menthol, sucrose, saccharin, saccharin sodium, xylitol, sorbitol, menthol, maltitol, lactitol, allulose, mannitol, isomalt, oligoisomaltitol, cyclamate, aspartame, acesulfame potassium, sucralose, sucralose, stevioside, thaumatin, and ammonium glycyrrhizinate.

5. The oral spray essence according to claim 1, Features: The antibacterial agent is one or more of cetylpyridinium chloride, domiphene, o-cymene-5-ol, chlorhexidine gluconate, benzethonium chloride, and lysozyme.

6. The oral spray essence according to claim 1, Features: The probiotics are one or more of lactobacillus, lactobacillus paracasei, lactobacillus plantarum, lactobacillus lysate fermentation product, lactobacillus acidophilus, lactobacillus reuteri, lactobacillus casei, bifidobacterium lactis, and lactobacillus salivarius.

7. The oral spray essence according to claim 1, Features: The pH buffer is one or more of citric acid, sodium citrate, potassium citrate, sodium lactate, lactic acid, potassium hydroxide, sodium hydroxide, disodium hydrogen phosphate, triethanolamine, and arginine.

8. The oral spray essence according to claim 1, Features: The surfactant is one or more of poloxamer 407, polysorbate-80, polysorbate-20, polyglycerol-4 oleate, PEG-20 hydrogenated castor oil, PEG-40 hydrogenated castor oil, lecithin, poloxamer 188, and poloxamer 184.

9. The oral spray essence according to claim 1, Features: The preservative is one or more of p-hydroxyacetophenone, caprylhydroxamic acid, monocaprylic glyceryl, phenoxyethanol, sodium benzoate, potassium sorbate, parabens, and phenoxyethanol.

10. The oral spray essence according to claim 1, Features: The moisturizing agent is one or more of glycerin, PEG-400, 1,3-propylene glycol, 1,3-butylene glycol, 1,2-hexanediol, 1,2-pentanediol, ethoxydiglycol, and caprylyl glycol.