Traditional Chinese medicine compound preparation for cold and cough symptoms as well as preparation method and application of traditional Chinese medicine compound preparation

Abstract

The invention relates to the technical field of traditional Chinese medicine, and particularly discloses a traditional Chinese medicine compound preparation for cold and cough symptoms and a preparation method and application thereof. The traditional Chinese medicine compound preparation is prepared from adenophora stricta, radix ophiopogonis, radix asteris, flos farfarae, radix polygonati officinalis, poria cocos, caulis bambusae in taeniam, cortex magnoliae officinalis, rhizoma acori graminei, radix curcumae, radix angelicae, pericarpium citri reticulatae, fructus aurantii, radix scrophulariae and rhizoma anemarrhenae; two symptoms of fever and swollen sore throat are stripped from a plurality of symptoms of cold, the traditional Chinese medicine composition focuses on treatment of cough and related symptoms, the problem of poor effect caused by face-to-face combination is avoided, and the formula is applicable to most cough patients with symptoms such as nasal obstruction, running nose, cough, vomiting, headache, aversion to cold, diarrhea and general discomfort. Even if the symptom of a patient is incomplete, the medicines in the formula can also play roles in protecting the functions of internal organs and preventing the internal organs.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicine, and specifically relates to a traditional Chinese medicine compound preparation for treating cold and cough symptoms, a preparation method and application thereof. Background Art

[0002] In the long history of traditional Chinese medicine, a wealth of experience and theoretical knowledge has been accumulated for the treatment of common colds and coughs. Traditional Chinese medicine believes that colds and coughs are caused by factors such as exogenous wind-cold, wind-heat or internal injury and phlegm, which lead to the failure of lung qi to spread and the imbalance of yin and yang. Therefore, the key to treating colds and coughs is to moisten the lungs and stop coughs, nourish yin and clear heat, resolve phlegm and relieve asthma, and take into account the coordination of the functions of the internal organs to achieve a state of yin and yang balance.

[0003] In traditional Chinese medicine, there are many prescriptions for colds, but a single prescription is often difficult to fully cover the complex symptoms of colds, especially when patients have more serious symptoms such as fever and sore throat. If you try to treat all symptoms at the same time with the same prescription, the effect is often not good and may even delay the disease. Summary of the invention

[0004] The object of the present invention is to provide a Chinese medicine compound preparation for treating cold and cough, a preparation method and application thereof, so as to solve the problems raised in the above-mentioned background technology.

[0005] To achieve the above object, the present invention provides the following technical solutions:

[0006] A Chinese medicine compound preparation for treating cold and cough symptoms, the preparation is composed of the following raw materials in parts by weight:

[0007] 6-9 parts of Adenophora Root, 6-9 parts of Ophiopogon japonicus, 5-9 parts of Aster Tataricus, 5-9 parts of Coltsfoot Flos, 6-12 parts of Polygonatum odoratum, 6-12 parts of Poria cocos, 6-12 parts of Rhizoma Anemarrhenae, 3-6 parts of Magnolia officinalis, 4-9 parts of Acorus calamus, 4-9 parts of Curcuma aromatica, 0-5 parts of Angelica dahurica, 6-9 parts of Citrus reticulata, 3-6 parts of Fructus Aurantii Immaturus, 5-10 parts of Scrophularia ningpoensis, and 7-8 parts of Rhizoma Anemarrhenae.

[0008] A method for preparing a Chinese medicine compound preparation for treating cold and cough symptoms comprises the following steps:

[0009] S1. Accurately weigh the above-mentioned API according to the prescribed weight;

[0010] S2. Mix the weighed APIs evenly;

[0011] S3, adding the mixed raw materials to an appropriate amount of water, simmering for 20 minutes to obtain a medicinal solution;

[0012] S4. Filter the medicinal solution, remove the residue, and obtain a clear decoction.

[0013] The application of the above-mentioned Chinese medicine compound preparation in the preparation of medicine for treating cold and cough symptoms.

[0014] Compared with the prior art, the present invention has the following beneficial effects:

[0015] (1) This formula separates fever and sore throat from the many symptoms of a cold and focuses on treating cough and its related symptoms, avoiding the problem of being too comprehensive but having poor results. This formula is suitable for most cough patients who present with symptoms such as nasal congestion, runny nose, cough, vomiting, headache, aversion to cold, diarrhea, and general discomfort. Even if the patient has incomplete symptoms, the drugs in the formula can still play a role in protecting the functions of the internal organs and preventing them.

[0016] (2) Each of the drugs in the formula performs its own function and is targeted at the main symptoms of cold and cough, so the efficacy is relatively significant. At the same time, it also focuses on repairing and preventing the damage caused by pathogens to the human body, thereby improving the overall treatment effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a process flow chart of the present invention. DETAILED DESCRIPTION

[0018] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0019] Embodiment 1:

[0020] See also Figure 1 As shown, a Chinese medicine compound preparation for treating cold and cough symptoms is composed of the following raw materials in parts by weight:

[0021] 8 parts of Adenophora, 8 parts of Radix Ophiopogonis, 7 parts of Aster, 7 parts of Flos Coltsfoot, 10 parts of Polygonatum, 10 parts of Poria, 10 parts of Rhizoma Anemarrhenae, 5 parts of Magnolia officinalis, 6 parts of Acorus calamus, 6 parts of Curcuma, 3 parts of Angelica dahurica, 8 parts of Citrus reticulatae, 5 parts of Fructus Aurantii Immaturus, 9 parts of Scrophulariae, and 6 parts of Rhizoma Anemarrhenae.

[0022] A method for preparing a Chinese medicine compound preparation for treating cold and cough symptoms comprises the following steps:

[0023] S1. Accurately weigh the above-mentioned API according to the prescribed weight;

[0024] S2. Mix the weighed APIs evenly, put the APIs into a container, and use a tool (such as a mortar or a stirring rod) to mix them evenly so that each API is evenly distributed;

[0025] S3. Add the mixed API to an appropriate amount of water, the amount of water should cover and slightly exceed the surface of the API, simmer, keep the liquid at a slight boil for 20 minutes, stir appropriately during this period to prevent the liquid from drying up or the API from sticking to the bottom, and obtain the liquid;

[0026] S4. Use a filter or gauze to filter the medicinal solution, remove the residue, and obtain a clear decoction.

[0027] According to the application of the above-mentioned Chinese medicine compound preparation in the preparation of medicine for treating cold and cough symptoms:

[0028] This preparation is for adults and needs to be decocted before taking. Adults should take it twice a day, 180-200 ml each time, half an hour after meals, for 2-3 consecutive days.

[0029] Embodiment 2:

[0030] The difference from Example 1 is that the Chinese medicine compound preparation for treating cold and cough symptoms is composed of the following raw materials in parts by weight:

[0031] 6 parts of Adenophora Root, 9 parts of Radix Ophiopogonis, 5 parts of Radix Asteris, 9 parts of Flos Coltsfoot, 6 parts of Polygonatum odoratum, 12 parts of Poria, 6 parts of Rhizoma Anemarrhenae, 3 parts of Magnolia Bark, 9 parts of Acorus Gramineus, 4 parts of Curcuma Radix, 6 parts of Pericarpium Citri Reticulatae, and 3 parts of Fructus Aurantii Immaturus.

[0032] The preparation method is the same as that in Example 1 and will not be described in detail here.

[0033] According to the application of the above-mentioned Chinese medicine compound preparation in the preparation of medicine for treating cold and cough symptoms:

[0034] This preparation is for children and needs to be decocted before taking. For children, the dosage should be increased by 10 ml per year of age and taken half an hour after a meal.

[0035] Embodiment three:

[0036] The difference from Example 1 is that the Chinese medicine compound preparation for treating cold and cough symptoms is composed of the following raw materials in parts by weight:

[0037] 9 parts of Adenophora Root, 6 parts of Radix Ophiopogonis, 9 parts of Aster Tataricus, 5 parts of Flos Coltsfoot, 12 parts of Polygonatum odoratum, 6 parts of Poria, 12 parts of Rhizoma Anemarrhenae, 6 parts of Magnolia Officinalis, 4 parts of Acorus Calamus, 9 parts of Curcuma Radix, 5 parts of Angelica Dahuricae, 9 parts of Pericarpium Citri Reticulatae, 6 parts of Fructus Aurantii Immaturus, 3 parts of Scrophulariae, and 5 parts of Rhizoma Anemarrhenae.

[0038] The preparation method and application method are the same as those in Example 1 and will not be described in detail here.

[0039] Application test examples:

[0040] A total of 90 patients with cold and cough of similar age, gender, and disease severity were randomly selected and divided into three groups, 30 cases in each group, to ensure that there was no significant difference in the basic conditions of the patients in each group before treatment (such as age, gender, disease course, etc.);

[0041] Experimental group 1: patients with cold and cough who used the Chinese medicine compound preparation of Example 1; Experimental group 2: patients with cold and cough who used the Chinese medicine compound preparation of Example 3; Control group: patients who used a commonly used Chinese patent medicine for cold and cough on the market;

[0042] Experimental group 1: the Chinese medicine compound preparation was prepared according to the preparation method of Example 1, and was taken continuously for 2-3 days according to the prescribed administration method (adults take twice a day, 180-200 ml each time, half an hour after a meal); Experimental group 2: the Chinese medicine compound preparation was prepared according to the preparation method of Example 3, and the administration method was the same as above; Control group: a commonly used Chinese patent medicine for cold and cough on the market was taken, and it was taken continuously for 3 days according to the recommended dosage and administration method on the drug instructions;

[0043] The changes in cough frequency and cough severity were recorded before treatment, on the first day after treatment, on the second day after treatment, and on the third day after treatment, as shown in the following table:

[0044]

[0045] The degree of improvement of symptoms was recorded. Each symptom was scored from 0 to 4 points according to its severity, with 0 indicating no symptoms and 4 indicating extremely severe symptoms, as shown in the following table:

[0046]

[0047] It can be seen from the above that the Chinese medicine compound preparation of the present invention has significant therapeutic effect in relieving cold symptoms and has good safety.

[0048] Among them, the main drugs are Adenophora Root and Radix Ophiopogonis, which mainly play the role of moistening the lungs and relieving coughs, nourishing yin and clearing away heat, aiming to balance the yin and yang of the lungs and correct the deviation of lung function from the source of breathing. These two drugs are the core of the formula as the main drugs, and treat the main causes of coughs;

[0049] The ministerial drugs are Aster, Coltsfoot, Tangerine Peel, Citrus Aurantii Immaturus, and Scrophularia, which have the effects of resolving phlegm and relieving cough (including cold phlegm and hot phlegm) and relieving asthma. Tangerine Peel can assist Aster and Coltsfoot to better resolve phlegm, and its Qi-regulating effect helps to improve the poor Qi movement caused by cough. Citrus Aurantii Immaturus can assist Magnolia officinalis to strengthen the effect of relieving asthma and relieve chest distension caused by cough. Scrophularia can treat the heat toxicity symptoms caused by cough, and its Yin-nourishing effect helps to assist Adenophora and Ophiopogon to nourish Yin and clear heat. As a ministerial drug, it assists the monarch drug to strengthen the effect of relieving cough and resolving phlegm, and relieve asthma symptoms.

[0050] The adjuvants are Polygonatum odoratum, Rhizoma Anemarrhenae, Magnolia officinalis, Poria cocos, Polygonatum odoratum and Rhizoma Anemarrhenae. Among them, Polygonatum odoratum nourishes yin and moistens dryness, clears stomach heat, and Rhizoma Anemarrhenae harmonizes the stomach and stops vomiting, which help relieve stomach discomfort caused by cough; Magnolia officinalis dries dampness and disperses fullness, relieves gas and relieves asthma, and has an auxiliary therapeutic effect on cough and asthma caused by phlegm and dampness; Poria cocos promotes diuresis and eliminates dampness, strengthens the spleen and calms the mind, which helps to improve excessive moisture in the body and restlessness caused by colds and coughs; Rhizoma Anemarrhenae clears heat, which helps to enhance the heat-clearing effect of the entire formula, and has a therapeutic effect on fever caused by cough. The adjuvant part mainly plays the role of repairing and preventing pathogenic factors from causing harm to the human body, and at the same time assists the monarch and ministerial drugs to enhance the overall efficacy.

[0051] The adjuvant drugs are Acorus calamus, Angelica dahurica, and Curcuma aromatica. Among them, Acorus calamus can open the orifices and resolve phlegm and dampness, which helps to improve symptoms such as dizziness and forgetfulness caused by phlegm and dampness obscuring the mind; Angelica dahurica can treat colds and headaches, and has a relieving effect on headaches caused by colds; Curcuma aromatica can break up blood stasis and promote the flow of qi, and has a dredging effect on blood stasis caused by cough. The adjuvant drug part treats cough and its complications from different angles, consolidating the overall therapeutic effect.

[0052] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A Chinese medicine compound preparation for treating cold and cough, characterized in that: The preparation is composed of the following raw materials in parts by weight: 6-9 parts of Adenophora Root, 6-9 parts of Ophiopogon japonicus, 5-9 parts of Aster Tataricus, 5-9 parts of Coltsfoot Flos, 6-12 parts of Polygonatum odoratum, 6-12 parts of Poria cocos, 6-12 parts of Rhizoma Anemarrhenae, 3-6 parts of Magnolia officinalis, 4-9 parts of Acorus calamus, 4-9 parts of Curcuma aromatica, 0-5 parts of Angelica dahurica, 6-9 parts of Citrus reticulata, 3-6 parts of Fructus Aurantii Immaturus, 0-10 parts of Scrophularia ningpoensis, and 0-8 parts of Rhizoma Anemarrhenae.

2. A method for preparing a Chinese medicine compound preparation for treating cold and cough symptoms, characterized in that: The following steps are involved: S1. Accurately weigh the above-mentioned API according to the prescribed weight; S2. Mix the weighed APIs evenly; S3, adding the mixed raw materials to an appropriate amount of water, simmering for 20 minutes to obtain a medicinal solution; S4. Filter the medicinal solution, remove the residue, and obtain a clear decoction.

3. Use of the Chinese medicine compound preparation according to claim 1 in the preparation of medicines for treating cold and cough symptoms.

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