Natural plant oil-controlling and acne-removing composition as well as preparation method and application thereof

Abstract

The invention relates to the technical field of cosmetic raw materials, and particularly discloses a natural plant oil-control acne-removal composition as well as a preparation method and application thereof. The natural plant oil control and acne removal composition comprises the following components in parts by mass: 8.45-29.7 parts of a humectant; 0.2-2 parts of a preservative; 11.65 to 28 parts of a composite extract; 40.3 to 79.7 parts of a solvent; the compound extract is prepared by compounding a fructus forsythiae fruit extract, a pueraria mirifica extract, blumea balsamifera oil, an althaea officinalis root extract, a rhizoma kaempferiae root extract and an artemisia annua extract. According to the present invention, the acne removing product has advantages of good acne removing effect and irritation reducing.

Description

Technical Field

[0001] The invention relates to the field of cosmetic raw materials, and in particular to a natural plant oil-controlling and acne-removing composition, a preparation method and an application thereof. Background Art

[0002] Acne is a chronic inflammatory skin disease of the pilosebaceous gland unit. The main causes of acne are excessive secretion of lipids by the sebaceous glands, inflammation and immune response, abnormal keratinization of the pilosebaceous gland ducts, and proliferation of follicular microorganisms such as Propionibacterium acnes. With the vigorous development of the social economy and the significant improvement in the quality of life of residents, people are paying more and more attention to their personal image and health. As a common skin disease, acne has a strong and growing market demand for treatment, especially among adolescents and young people. Due to the increased pressure of study and work and irregular living habits, the acne problem has become increasingly prominent and has become the focus of attention from all walks of life.

[0003] As the treatment desire of acne patients grows strongly, the strong demand for efficacy drives the market size of acne-removing skin care products to continue to expand. There are many kinds of acne-removing products on the market. The mainstream acne-removing products can be roughly divided into three types: products with acid as the core acne-removing ingredient, products with colloidal sulfur as the core acne-removing ingredient, and products with strong fungicides as the core ingredients. Products with acid as the core acne-removing ingredient mainly include azelaic acid, salicylic acid, mandelic acid, etc., which mainly solve the problem of closed comedones. Although they can accelerate the shedding of stratum corneum cells, thereby promoting the replacement and reconstruction of epidermal cells, temporary erythema, stinging, itching, burning and other discomforts will occur during use, and the skin will become overly dry, scaly and peeling. If used for a long time, it will cause the stratum corneum to be too thin and the skin barrier to be fragile. Products with colloidal sulfur as the core acne-removing ingredient use high-concentration colloidal sulfur as the core acne-removing ingredient. They have a strong bactericidal effect on red acne, raised acne, and white pustular acne, but they have a strong odor and a weak anti-inflammatory effect on inflammatory acne, and they may cause pigmentation problems in the later stages of acne. The main ingredients of acne-removing products with strong bactericides as the core ingredient are pyronin and metronidazole. Although they have good bactericidal effects, they are prone to drug resistance and strong irritation, and are not friendly to sensitive skin.

[0004] In summary, existing acne removal products are difficult to meet the requirements of strong acne removal effect, mildness and low irritation, so there is still room for improvement. Summary of the invention

[0005] In order to make acne-removing products have better acne-removing effects while reducing irritation, the present application provides a natural plant oil-controlling acne-removing composition, a preparation method and an application thereof.

[0006] In the first aspect, the present application provides a natural plant oil-controlling and acne-removing composition, which adopts the following technical solution: A natural plant oil-controlling and acne-removing composition, comprising the following components in parts by weight: Moisturizer 8.45-29.7 parts; Preservative 0.2-2 parts; Composite extract 11.65-28 parts; Solvent 40.3-79.7 parts; The composite extract is a compound of forsythia fruit extract, pueraria root extract, linalool oil, marshmallow root extract, kaempferia galanga root extract and artemisia annua extract.

[0007] By adopting the above technical scheme, through the compounding of Forsythia suspensa fruit extract, Pueraria lobata root extract, Artemisia annua oil, Althaea officinalis root extract, Kaempferia galanga root extract, and Artemisia annua extract, the natural plant oil control and acne removal composition can achieve better oil control, anti-inflammatory, antibacterial, soothing and other effects, and has a very significant acne removal effect. At the same time, it is relatively mild and not easy to irritate the skin, and is very suitable for sensitive skin. Moreover, the combination of various active ingredients can effectively inhibit melanin synthesis, thereby reducing the deposition of melanin in acne during the acne removal process, thereby preventing acne marks and making the skin whiter and more beautiful after repair.

[0008] Preferably, the mass ratio of the Forsythia suspensa fruit extract, Pueraria lobata root extract, Artemisia annua oil, Althaea officinalis root extract, Kaempferia galanga root extract and Artemisia annua extract is 0.35-1.05: 0.35-1.4: 10-20: 0.5-1.5: 0.1-3: 0.35-1.05.

[0009] By adopting the above technical scheme, by specifically selecting the mass ratios of Forsythia suspensa fruit extract, Pueraria lobata root extract, Artemisia annua oil, Althaea officinalis root extract, Kaempferia galanga root extract, and Artemisia annua extract, various active ingredients are combined in specific ratios to exert a better synergistic effect, especially a better effect in inhibiting melanin synthesis, which can better prevent dark acne marks from being left after acne is cured.

[0010] Preferably, the moisturizing agent is a compound of butylene glycol, glycerol and 1,2-hexanediol.

[0011] By adopting the above technical solution and specifically selecting the combination of butylene glycol, glycerin and 1,2-hexanediol, the moisturizing effect is better, and acne can be removed while better caring for the skin, making the skin healthier.

[0012] Preferably, the mass ratio of butanediol, glycerol and 1,2-hexanediol is 3.7-14.1:4.7-14.1:0.05-1.5.

[0013] By adopting the above technical solution and specifically selecting the mass ratio of butylene glycol, glycerin and 1,2-hexanediol, the moisturizing effect is better, which can better assist in regulating the water and oil balance of the skin and help improve the acne removal effect.

[0014] Preferably, the preservative is p-hydroxyacetophenone.

[0015] By adopting the above technical solution and specifically selecting p-hydroxyacetophenone, a good antiseptic effect is achieved so that the shelf life of the product is longer, while the irritation is lower and it is not easy to hurt the skin, and the mild and non-irritating characteristics of the product can be better maintained.

[0016] Preferably, the solvent is deionized water.

[0017] By adopting the above technical solution and specifically selecting deionized water, the acne-removing composition is more easily absorbed by the skin and has a better effect of repairing the skin.

[0018] In a second aspect, the present application provides a method for preparing a natural plant oil-controlling and acne-removing composition, using the following technical solution: A method for preparing the above-mentioned natural plant oil-controlling and acne-removing composition comprises the following steps: Step 1), mixing the moisturizer, preservative, composite extract and solvent at room temperature to obtain a mixture; Step 2), filtering the mixture and discharging the mixture to obtain a natural plant oil-controlling and acne-removing composition.

[0019] By adopting the above technical scheme, the prepared natural plant oil-controlling acne-removing composition has significant acne-removing effect, is relatively mild, has low irritation, is not easy to damage the skin, and can effectively inhibit melanin and reduce the formation of dark spots and acne marks after the acne-affected areas are healed.

[0020] In the third aspect, the present application provides an application of a natural plant oil control and acne removal composition, adopting the following technical scheme: an application of the above-mentioned natural plant oil control and acne removal composition, wherein the natural plant oil control and acne removal composition is added to cosmetics for preparing cosmetics with oil control and acne removal effects, and the mass content of the natural plant oil control and acne removal composition in the cosmetics is 1-10%.

[0021] By adopting the above technical solution, a small amount of the natural plant oil-controlling and acne-removing composition can be added to cosmetics to make the cosmetics have significant acne-removing effects, effectively control costs, and make the process difficulty of the cosmetics production process lower, thus having higher economic value.

[0022] In summary, this application has the following beneficial effects: 1. Because the present application compounds Forsythia suspensa fruit extract, Pueraria lobata root extract, Artemisia selengensis oil, Althaea officinalis root extract, Kaempferia galanga root extract, and Artemisia annua extract, the natural plant oil control and acne removal composition can achieve good oil control, anti-inflammatory, antibacterial, soothing and other effects, and has a very significant acne removal effect. At the same time, it is relatively mild and not easy to irritate the skin, and is very suitable for sensitive skin. Moreover, the combination of various active ingredients can effectively inhibit melanin synthesis, thereby reducing the deposition of melanin in acne during the acne removal process, thereby preventing acne marks and making the skin whiter and more beautiful after repair.

[0023] 2. In the present application, it is preferred to specifically select the mass ratio of Forsythia suspensa fruit extract, Pueraria lobata root extract, Blumea balsamifera oil, Althaea officinalis root extract, Kaempferia galanga root extract, and Artemisia annua extract, so that various active ingredients are combined in a specific ratio to exert a better synergistic effect, especially a better effect of inhibiting melanin synthesis, which can better prevent dark acne marks from being left after acne is cured.

[0024] 3. In the present application, it is preferred to specifically select a compound of butanediol, glycerol and 1,2-hexanediol, which has a better moisturizing effect, can remove acne while better caring for the skin, and make the skin healthier. DETAILED DESCRIPTION

[0025] The present application is further described in detail below with reference to the embodiments.

[0026] Example 1 A natural plant oil-controlling and acne-removing composition, comprising the following components: Humectants, preservatives, complex extracts, solvents.

[0027] The moisturizer is a mixture of butylene glycol, glycerin and 1,2-hexanediol.

[0028] Butanediol was purchased from Jinan Rongguang Chemical Co., Ltd., CAS No.: 110-63-4.

[0029] Glycerol was purchased from Yuanyue (Guangdong) Chemical Co., Ltd., CAS No.: 56-81-5.

[0030] 1,2-Hexanediol was purchased from Zhongshan Dixin Chemical Co., Ltd., CAS No.: 6920-22-5.

[0031] The preservative was p-hydroxyacetophenone, which was purchased from Wuhan Kemik Biopharmaceutical Technology Co., Ltd., CAS No.: 99-93-4.

[0032] The compound extract is a combination of Forsythia suspensa fruit extract, Pueraria lobata root extract, Artemisia annua oil, Marshmallow root extract, Kaempferia galanga root extract and Artemisia annua extract.

[0033] The forsythia fruit extract was purchased from Quzhou Zhanhong Biotechnology Co., Ltd.

[0034] Pueraria lobata extract was purchased from Quzhou Zhanhong Biotechnology Co., Ltd.

[0035] Ai Na sesame oil was purchased from Guangzhou Rice Biotechnology Co., Ltd.

[0036] Marshmallow root extract was purchased from Guangzhou Youran Biotechnology Co., Ltd.

[0037] Kaempferia galanga root extract was purchased from Shenzhen Excellence Biotechnology Co., Ltd.

[0038] Artemisia annua extract was purchased from Quzhou Zhanhong Biotechnology Co., Ltd.

[0039] The solvent is deionized water.

[0040] The preparation method of the natural plant oil-controlling and acne-removing composition comprises the following steps: Step 1), 3.7 kg of butylene glycol, 4.7 kg of glycerol, 0.05 kg of 1,2-hexanediol, 0.2 kg of p-hydroxyacetophenone, 0.35 kg of forsythia fruit extract, 0.35 kg of pueraria root extract, 10 kg of linalool oil, 0.5 kg of marshmallow root extract, 0.1 kg of kaempferia root extract, 0.35 kg of artemisia annua extract, and 79.7 kg of deionized water are put into a stirring tank at a speed of 120 r / min, stirred at room temperature for 30 min, mixed evenly, and obtained a mixture.

[0041] Step 2), filtering the mixture through a 200-mesh filter cloth to obtain a natural plant oil-controlling and anti-acne composition.

[0042] Example 2 A natural plant oil-controlling and acne-removing composition, comprising the following components: Humectants, preservatives, complex extracts, solvents.

[0043] The moisturizer is a mixture of butylene glycol, glycerin and 1,2-hexanediol.

[0044] Butanediol was purchased from Jinan Rongguang Chemical Co., Ltd., CAS No.: 110-63-4.

[0045] Glycerol was purchased from Yuanyue (Guangdong) Chemical Co., Ltd., CAS No.: 56-81-5.

[0046] 1,2-Hexanediol was purchased from Zhongshan Dixin Chemical Co., Ltd., CAS No.: 6920-22-5.

[0047] The preservative was p-hydroxyacetophenone, which was purchased from Wuhan Kemik Biopharmaceutical Technology Co., Ltd., CAS No.: 99-93-4.

[0048] The compound extract is a combination of Forsythia suspensa fruit extract, Pueraria lobata root extract, Artemisia annua oil, Marshmallow root extract, Kaempferia galanga root extract and Artemisia annua extract.

[0049] The forsythia fruit extract was purchased from Quzhou Zhanhong Biotechnology Co., Ltd.

[0050] Pueraria lobata extract was purchased from Quzhou Zhanhong Biotechnology Co., Ltd.

[0051] Ai Na sesame oil was purchased from Guangzhou Rice Biotechnology Co., Ltd.

[0052] Marshmallow root extract was purchased from Guangzhou Youran Biotechnology Co., Ltd.

[0053] Kaempferia galanga root extract was purchased from Shenzhen Excellence Biotechnology Co., Ltd.

[0054] Artemisia annua extract was purchased from Quzhou Zhanhong Biotechnology Co., Ltd.

[0055] The solvent is deionized water.

[0056] The preparation method of the natural plant oil-controlling and acne-removing composition comprises the following steps: Step 1), 8.9 kg of butylene glycol, 9.4 kg of glycerol, 0.78 kg of 1,2-hexanediol, 1.1 kg of p-hydroxyacetophenone, 0.7 kg of forsythia fruit extract, 0.88 kg of pueraria root extract, 15 kg of linalool oil, 1 kg of marshmallow root extract, 1.55 kg of kaempferia galanga root extract, 0.7 kg of artemisia annua extract, and 60 kg of deionized water are put into a stirring tank at a speed of 120 r / min, stirred at room temperature for 30 min, mixed evenly, and obtained a mixture.

[0057] Step 2), filtering the mixture through a 200-mesh filter cloth to obtain a natural plant oil-controlling and anti-acne composition.

[0058] Example 3 A natural plant oil-controlling and acne-removing composition, comprising the following components: Humectants, preservatives, complex extracts, solvents.

[0059] The moisturizer is a mixture of butylene glycol, glycerin and 1,2-hexanediol.

[0060] Butanediol was purchased from Jinan Rongguang Chemical Co., Ltd., CAS No.: 110-63-4.

[0061] Glycerol was purchased from Yuanyue (Guangdong) Chemical Co., Ltd., CAS No.: 56-81-5.

[0062] 1,2-Hexanediol was purchased from Zhongshan Dixin Chemical Co., Ltd., CAS No.: 6920-22-5.

[0063] The preservative was p-hydroxyacetophenone, which was purchased from Wuhan Kemik Biopharmaceutical Technology Co., Ltd., CAS No.: 99-93-4.

[0064] The compound extract is a combination of Forsythia suspensa fruit extract, Pueraria lobata root extract, Artemisia annua oil, Marshmallow root extract, Kaempferia galanga root extract and Artemisia annua extract.

[0065] The forsythia fruit extract was purchased from Quzhou Zhanhong Biotechnology Co., Ltd.

[0066] Pueraria lobata extract was purchased from Quzhou Zhanhong Biotechnology Co., Ltd.

[0067] Ai Na sesame oil was purchased from Guangzhou Rice Biotechnology Co., Ltd.

[0068] Marshmallow root extract was purchased from Guangzhou Youran Biotechnology Co., Ltd.

[0069] Kaempferia galanga root extract was purchased from Shenzhen Excellence Biotechnology Co., Ltd.

[0070] Artemisia annua extract was purchased from Quzhou Zhanhong Biotechnology Co., Ltd.

[0071] The solvent is deionized water.

[0072] The preparation method of the natural plant oil-controlling and acne-removing composition comprises the following steps: Step 1), 14.1kg of butylene glycol, 14.1kg of glycerol, 1.5kg of 1,2-hexanediol, 2kg of p-hydroxyacetophenone, 1.05kg of forsythia fruit extract, 1.4kg of pueraria root extract, 20kg of linalool oil, 1.5kg of marshmallow root extract, 3kg of kaempferia root extract, 1.05kg of artemisia annua extract, and 40.3kg of deionized water are put into a stirring tank at a speed of 120r / min, stirred at room temperature for 30min, mixed evenly, and obtained a mixture.

[0073] Step 2), filtering the mixture through a 200-mesh filter cloth to obtain a natural plant oil-controlling and anti-acne composition.

[0074] Comparative Example 1 A natural plant oil-controlling and acne-removing composition, compared with Example 2, differs only in that: In the composite extract, witch hazel extract was used to replace the forsythia fruit extract in equal amounts.

[0075] The witch hazel extract was purchased from Xi'an Wuling Biotechnology Co., Ltd.

[0076] Comparative Example 2 A natural plant oil-controlling and acne-removing composition, compared with Example 2, differs only in that: In the composite extract, chamomile extract is used to replace kudzu root extract in equal amounts.

[0077] Chamomile extract was purchased from Shaanxi Muyun Biotechnology Co., Ltd.

[0078] Comparative Example 3 A natural plant oil-controlling and acne-removing composition, compared with Example 2, differs only in that: In the composite extract, tea tree essential oil is used to replace Ailanthus oil in equal amounts.

[0079] Tea tree essential oil was purchased from Wuhan Jixinyibang Biotechnology Co., Ltd.

[0080] Comparative Example 4 A natural plant oil-controlling and acne-removing composition, compared with Example 2, differs only in that: In the composite extract, an equal amount of Centella asiatica extract is used to replace the marshmallow root extract.

[0081] Centella asiatica extract was purchased from Fufeng Snot Biotechnology Co., Ltd.

[0082] Comparative Example 5 A natural plant oil-controlling and acne-removing composition, compared with Example 2, differs only in that: In the composite extract, the calendula officinalis flower extract was used to replace the kaempferia galanga root extract in equal amounts.

[0083] Calendula officinalis extract was purchased from Shanyang Lianfeng Biotechnology Co., Ltd.

[0084] Comparative Example 6 A natural plant oil-controlling and acne-removing composition, compared with Example 2, differs only in that: In the composite extract, rosemary extract is used to replace the artemisia annua extract in equal amounts.

[0085] Rosemary Extract Hubei Haijia Biotechnology Co., Ltd.

[0086] Comparative Example 7 A natural plant oil-controlling and acne-removing composition, compared with Example 2, differs only in that: In the composite extract, witch hazel extract is used to replace the forsythia fruit extract in an equal amount, chamomile extract is used to replace the pueraria root extract in an equal amount, tea tree essential oil is used to replace the linalool oil in an equal amount, Centella asiatica extract is used to replace the marshmallow root extract in an equal amount, calendula officinalis extract is used to replace the galangal root extract in an equal amount, and rosemary extract is used to replace the artemisia annua extract in an equal amount.

[0087] The witch hazel extract was purchased from Xi'an Wuling Biotechnology Co., Ltd.

[0088] Chamomile extract was purchased from Shaanxi Muyun Biotechnology Co., Ltd.

[0089] Tea tree essential oil was purchased from Wuhan Jixinyibang Biotechnology Co., Ltd.

[0090] Centella asiatica extract was purchased from Fufeng Snot Biotechnology Co., Ltd.

[0091] Calendula officinalis extract was purchased from Shanyang Lianfeng Biotechnology Co., Ltd.

[0092] Rosemary Extract Hubei Haijia Biotechnology Co., Ltd.

[0093] Experiment 1 A number of volunteers aged 18-25 years old with more than 10 facial acne were recruited, and the volunteers were randomly divided into groups of ten. The groups used the test samples prepared from the natural plant oil-controlling and anti-acne compositions of the embodiments and comparative examples once in the morning and evening every day, and 5 ml of the test samples were evenly applied on the face each time for 30 days.

[0094] Samples to be tested: Take 5 g of the natural plant oil-controlling and anti-acne composition and 95 g of deionized water, mix them evenly, and obtain a sample to be tested.

[0095] Before using the test samples, the number of pimples on the volunteers' faces was counted and recorded as the initial number of pimples. After using the test samples for 30 consecutive days, the number of pimples on the volunteers' faces was counted again and recorded as the number of pimples after 30 days of repair.

[0096] The experimental data of each group were averaged.

[0097] Experiment 2 According to SNT2329-2009 "Chicken Embryo Chorioallantoic Membrane Test for Eye Irritation and Corrosion of Cosmetics", the irritation score (IS) of the natural plant oil-controlling and anti-acne composition of each embodiment and comparative example was tested. During the inspection, the samples were not diluted.

[0098] Each group of experiments was performed 10 times, and the experimental data were averaged.

[0099] Experiment 3 According to T / GDCA006-2021 "Test method for inhibition of tyrosinase activity by cosmetic raw materials (in vitro method)", the tyrosinase inhibition rate of the test samples prepared from the natural plant oil control and acne anti-compositions of each embodiment and comparative example was tested.

[0100] Samples to be tested: Take 5 g of the natural plant oil-controlling and anti-acne composition and 95 g of deionized water, mix them evenly, and obtain a sample to be tested.

[0101] Each group of experiments was performed 10 times, and the experimental data were averaged.

[0102] The specific experimental data of Experiments 1-3 are shown in Table 1.

[0103] According to the data comparison of each embodiment and the comparative example in Table 1, each embodiment eliminates acne significantly faster than each comparative example, which shows that each embodiment has better acne removal effect than each comparative example, and each embodiment is less irritating than each comparative example, each embodiment is milder, and the tyrosinase inhibition rate of each embodiment is significantly higher than that of each comparative example, which shows that each embodiment has significantly better effect of inhibiting melanin synthesis than each comparative example, and can better prevent the occurrence of dark spots and acne marks after acne heals.

[0104] Each comparative example uses conventional plant extracts with anti-inflammatory, oil-control, bactericidal and other effects to replace the Forsythia fruit extract, Pueraria root extract, Blumea balsamina oil, Althaea officinalis root extract, Kaempferia galanga root extract, and Artemisia annua extract in each embodiment alone or in whole. Although it can also have the effect of removing acne, the composite system of Forsythia fruit extract, Pueraria root extract, Blumea balsamina oil, Althaea officinalis root extract, Kaempferia galanga root extract, and Artemisia annua extract is destroyed, resulting in a decrease in the acne removal effect, especially a significant decrease in the effect of inhibiting melanin synthesis, making it difficult to achieve the effect of removing acne while preventing the formation of dark spots and acne marks after acne healing.

[0105] This specific embodiment is merely an explanation of the present application and is not a limitation of the present application. After reading this specification, those skilled in the art may make modifications to the present embodiment without any creative contribution as needed. However, as long as it is within the scope of the claims of the present application, it shall be protected by the patent law.

Claims

1. A natural plant oil-controlling and acne-removing composition, characterized in that: The composition includes the following components in parts by weight: Moisturizer 8.45-29.7 parts; Preservative 0.2-2 parts; Composite extract 11.65-28 parts; Solvent 40.3-79.7 parts; The composite extract is a compound of forsythia fruit extract, pueraria root extract, linalool oil, marshmallow root extract, kaempferia galanga root extract and artemisia annua extract.

2. A natural plant oil-controlling and acne-removing composition according to claim 1, characterized in that: The mass ratio of the forsythia fruit extract, pueraria root extract, linalool oil, marshmallow root extract, kaempferia galanga root extract and artemisia annua extract is 0.35-1.05: 0.35-1.4: 10-20: 0.5-1.5: 0.1-3: 0.35-1.

05.

3. A natural plant oil-controlling and acne-removing composition according to claim 1, characterized in that: The moisturizing agent is a compound of butylene glycol, glycerol and 1,2-hexanediol.

4. A natural plant oil-controlling and acne-removing composition according to claim 3, characterized in that: The mass ratio of the butanediol, glycerol and 1,2-hexanediol is 3.7-14.1:4.7-14.1:0.05-1.

5.

5. A natural plant oil-controlling and acne-removing composition according to claim 1, characterized in that: The preservative is p-hydroxyacetophenone.

6. A natural plant oil-controlling and acne-removing composition according to claim 1, characterized in that: The solvent is deionized water.

7. A method for preparing the natural plant oil-controlling and anti-acne composition according to any one of claims 1 to 6, characterized in that: The following steps are involved: Step 1), mixing the moisturizer, preservative, composite extract and solvent uniformly at room temperature to obtain a mixture; Step 2), filtering the mixture and discharging the mixture to obtain a natural plant oil-controlling and acne-removing composition.

8. An application of the natural plant oil-controlling and anti-acne composition according to any one of claims 1 to 6, characterized in that: The natural plant oil-controlling and acne-removing composition is added to cosmetics to prepare cosmetics with oil-controlling and acne-removing effects, and the mass content of the natural plant oil-controlling and acne-removing composition in the cosmetics is 1-10%.

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