Novel foaming antibacterial itching-relieving lotion

Abstract

The invention discloses a novel foaming antibacterial itching-relieving lotion, and belongs to the technical field of medical application. The traditional Chinese medicine formula is prepared from radix stemonae, fructus cnidii, radix sophorae flavescentis, flos chrysanthemi indici, herba epimedii, rhizoma polygoni cuspidati, deionized water, decyl glucoside, cocamidopropyl betaine, sodium chloride, disodium cocoamphodiacetate, propylene glycol, PEG-150 distearate, phenoxyethanol, benzoic acid, glycerol caprylate and chlorhexidine diacetate. The scheme provides the novel foaming lotion with the characteristics of bacteriostasis, itching relieving, foaming cleaning and the like, surfactants such as decyl glucoside, cocamidopropyl betaine and the like have excellent cleaning ability and foamability, are mild and non-irritant to skin and are suitable for sensitive skin, and the raw materials are biodegradable substances, are free of environmental pollution, and are safe and environment-friendly. And the product is simple in preparation process, low in cost, environment-friendly and pollution-free, and has relatively high market popularization value.

Description

Technical Field

[0001] The invention belongs to the technical field of medical application, and in particular relates to a novel foaming antibacterial and antipruritic lotion. Background Art

[0002] Skin is the largest organ in the human body and is easily affected by various external factors and internal conditions, leading to a variety of skin problems such as bacterial or fungal infections, dermatitis, eczema, etc. These problems are often accompanied by symptoms such as itching, redness, swelling, and inflammation, which bring inconvenience and pain to patients' daily lives. Traditional Chinese herbal medicine has a long history and good reputation in skin care.

[0003] Natural medicinal materials such as Phellodendron chinense, Stemona tuber, Cnidium monnieri, Sophora flavescens contain a variety of bioactive ingredients with anti-inflammatory, antibacterial, antifungal and antipruritic effects. The development of lotion products combining these natural ingredients has important market value and health significance. The foaming and cleaning function of traditional Chinese medicine lotions is weak, and they cannot stay well on the surface of the skin and are poorly absorbed. For this reason, we propose a new type of foaming antibacterial and antipruritic lotion to solve the above problems. Summary of the invention

[0004] The purpose of the present invention is to provide a novel foaming antibacterial and antipruritic lotion to solve the problems raised in the above background technology.

[0005] To achieve the above-mentioned purpose, the present invention provides the following technical scheme: a novel foaming antibacterial and antipruritic lotion, comprising the following raw materials: phellodendron, radix stemonae, fructus cnidii, sophora flavescens, chrysanthemum indici, epimedium, polygonum cuspidatum, deionized water, decyl glucoside, cocamidopropyl betaine, sodium chloride, disodium cocoamphodiacetate, propylene glycol, PEG-150 distearate, phenoxyethanol, benzoic acid, glyceryl caprylate and chlorhexidine diacetate.

[0006] Preferably, a novel foaming antibacterial and antipruritic lotion preparation process comprises the following steps:

[0007] (1) Preparation

[0008] A. Add 1-3g of Phellodendron chinense, 1-3g of Stemona officinalis, 1-3g of Cnidium monnieri, 1-3g of Sophora flavescens, 1-3g of Chrysanthemum indici, 1-3g of Epimedium brevicornum, and 1-3g of Polygonum cuspidatum to an extraction tank and add 60-100g of deionized water, soak for 1 hour, heat, boil for 1 hour, and filter with 100 mesh coarse filtration and 400 mesh fine filtration after cooling to obtain a mixed solution A45-70g;

[0009] B1, 1-8 g of decyl glucoside and 1-10 g of deionized water are mixed evenly to obtain a mixed solution B1 for standby use;

[0010] B2, 1-6 g of cocamidopropyl betaine, 0.1-1.2 g of sodium chloride and 2-15 g of deionized water are mixed to obtain a standby mixed solution B2;

[0011] B3, 1-4 g of disodium cocoamphoacetate, 0.1-1.5 g of sodium chloride and 3-10 g of deionized water are mixed to obtain a standby mixed solution B3;

[0012] B4. Place 0.5-3 g of PEG-150 distearate in a container for later use;

[0013] C1, 0.5-4 g of propylene glycol and 0.01-0.2 g of chlorhexidine diacetate are uniformly mixed to obtain a standby mixed solution C1;

[0014] D. Mix 10-20 g of deionized water and 0.1-2.5 g of sodium chloride to obtain a mixed solution D for standby use;

[0015] E. Evenly mix 0.1-0.65 g of phenoxyethanol, 0.1-0.3 g of propylene glycol, 0.05-0.3 g of benzoic acid and 0.025-0.1 g of glyceryl caprylate to obtain a mixed solution E for standby use.

[0016] (2) Mixing

[0017] Add A to the main pot, add B1, B2 and B3 in turn, heat to 80-85℃ and stir evenly until it is homogeneous and transparent;

[0018] Add B4 to the main pot, heat to 80-85℃, stir until homogeneous and transparent, and keep warm for 30-60 minutes;

[0019] Continue stirring at room temperature until the temperature drops to 45-50°C, add C1, and stir evenly;

[0020] Continue stirring and slowly cool down to 30-35℃, add E and D in turn, stir evenly, and wait for cooling.

[0021] (3) Submission for inspection

[0022] Take samples and send them to the laboratory to test the appearance, smell, pH and other indicators.

[0023] (4) Bottling

[0024] Dispense the product into vials and seal them.

[0025] Compared with the prior art, the present invention has the following beneficial effects:

[0026] The present invention provides a novel foaming lotion with the characteristics of antibacterial and antipruritic, moisturizing, mild and non-irritating. Surfactants such as decyl glucoside and cocamidopropyl betaine have excellent cleaning power and foaming properties, are mild and non-irritating to the skin, and are suitable for use on sensitive skin. The raw materials are all biodegradable substances and are pollution-free to the environment. The preparation process of the product is simple, the cost is low, and it is environmentally friendly and pollution-free, and has a high market promotion value. DETAILED DESCRIPTION

[0027] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0028] The invention provides a novel foaming antibacterial and antipruritic lotion, which comprises the following raw materials: phellodendron chinense, stemonae, cnidium monnieri, sophora flavescens, wild chrysanthemum, epimedium, polygonum cuspidatum, deionized water, decyl glucoside, cocamidopropyl betaine, sodium chloride, disodium cocoamphodiacetate, propylene glycol, PEG-150 distearate, phenoxyethanol, benzoic acid, glyceryl caprylate and chlorhexidine diacetate.

[0029] In this embodiment, a novel foaming antibacterial and antipruritic lotion preparation process comprises the following steps:

[0030] (1) Preparation

[0031] A. Add 1-3g of Phellodendron chinense, 1-3g of Stemona officinalis, 1-3g of Cnidium monnieri, 1-3g of Sophora flavescens, 1-3g of Chrysanthemum indici, 1-3g of Epimedium brevicornum, and 1-3g of Polygonum cuspidatum to an extraction tank and add 60-100g of deionized water, soak for 1 hour, heat, boil for 1 hour, and filter with 100 mesh coarse filtration and 400 mesh fine filtration after cooling to obtain a mixed solution A45-70g;

[0032] B1, 1-8 g of decyl glucoside and 1-10 g of deionized water are mixed evenly to obtain a mixed solution B1 for standby use;

[0033] B2, 1-6 g of cocamidopropyl betaine, 0.1-1.2 g of sodium chloride and 2-15 g of deionized water are mixed to obtain a standby mixed solution B2;

[0034] B3, 1-4 g of disodium cocoamphoacetate, 0.1-1.5 g of sodium chloride and 3-10 g of deionized water are mixed to obtain a standby mixed solution B3;

[0035] B4. Place 0.5-3 g of PEG-150 distearate in a container for later use;

[0036] C1, 0.5-4 g of propylene glycol and 0.01-0.2 g of chlorhexidine diacetate are uniformly mixed to obtain a standby mixed solution C1;

[0037] D. Mix 10-20 g of deionized water and 0.1-2.5 g of sodium chloride to obtain a mixed solution D for standby use;

[0038] E. Evenly mix 0.1-0.65 g of phenoxyethanol, 0.1-0.3 g of propylene glycol, 0.05-0.3 g of benzoic acid and 0.025-0.1 g of glyceryl caprylate to obtain a mixed solution E for standby use.

[0039] (2) Mixing

[0040] Add A to the main pot, add B1, B2 and B3 in turn, heat to 80-85℃ and stir evenly until it is homogeneous and transparent;

[0041] Add B4 to the main pot, heat to 80-85℃, stir until homogeneous and transparent, and keep warm for 30-60 minutes;

[0042] Continue stirring at room temperature until the temperature drops to 45-50°C, add C1, and stir evenly;

[0043] Continue stirring and slowly cool down to 30-35℃, add E and D in turn, stir evenly, and wait for cooling.

[0044] (3) Submission for inspection

[0045] Take samples and send them to the laboratory to test the appearance, smell, pH and other indicators.

[0046] (4) Bottling

[0047] Dispense the product into vials and seal them.

[0048] Further:

[0049] Huangbai: It has the effects of clearing away heat and dampness, purging fire and detoxifying, and has a good therapeutic effect on skin inflammation and infection.

[0050] Stemona: It has the effects of clearing away heat and detoxifying, relieving cough and relieving asthma, and has a certain auxiliary therapeutic effect on skin diseases.

[0051] Cnidium monnieri: It has the effects of dispelling wind and dampness, killing insects and relieving itching, and has a good effect in relieving skin itching.

[0052] Sophora flavescens: It has the effects of clearing away heat and detoxifying, drying dampness and relieving itching, and has a good therapeutic effect on skin diseases such as dermatitis and eczema.

[0053] Wild chrysanthemum: It has the effects of clearing away heat and detoxifying, reducing swelling and relieving pain, and has a good therapeutic effect on skin inflammation and infection.

[0054] Epimedium: It has the effects of nourishing the kidney and strengthening yang, resisting fatigue, and has certain health care effects on the skin.

[0055] Polygonum cuspidatum: It has the effects of clearing away heat and detoxifying, promoting dampness and relieving constipation, and has a good therapeutic effect on skin inflammation and infection.

[0056] Deionized water: used as a solvent to extract and mix various pharmaceutical ingredients.

[0057] Decyl Glucoside: It has cleansing, foaming and emulsifying effects, and can increase the cleansing power and foaming properties of the lotion.

[0058] Cocamidopropyl Betaine: It has cleansing, foaming and emulsifying effects, and can increase the cleansing power and foaming properties of the lotion.

[0059] Sodium chloride: It has the function of regulating osmotic pressure and maintaining the stability of the washing solution.

[0060] Disodium Cocoamphodiacetate: It has cleansing, foaming and emulsifying effects, and can increase the cleansing power and foaming properties of the lotion.

[0061] Propylene glycol: acts as a humectant and solvent to increase the moisturizing properties and stability of the product.

[0062] PEG-150 Distearate: acts as an emulsifier and stabilizer to improve the stability and feel of the product.

[0063] Phenoxyethanol: It has antibacterial and preservative effects and can increase the shelf life of the lotion.

[0064] Benzoic acid: It has antibacterial and antiseptic effects and can increase the shelf life of the lotion.

[0065] Glyceryl Caprylate: It has the function of moisturizing and nourishing the skin, improving symptoms such as dry and rough skin.

[0066] Chlorhexidine diacetate: It has antibacterial and anti-inflammatory effects, and has a good therapeutic effect on skin diseases such as dermatitis and eczema.

[0067] The working principle and use process of the present invention:

[0068] Add 1-3g of Phellodendron chinense, 1-3g of Stemona tuber, 1-3g of Cnidium monnieri, 1-3g of Sophora flavescens, 1-3g of Chrysanthemum indici, 1-3g of Epimedium brevicornum, and 1-3g of Polygonum cuspidatum to an extraction tank and add 60-100g of deionized water, and soak for 1 hour. Then, heat the extraction tank to boil the contents for 1 hour. After that, cool the extract and filter it with 100 mesh coarse filtration and 400 mesh fine filtration for later use, to obtain 45-70g of mixed solution A;

[0069] In addition, prepare standby mixed solutions B1 to B4, C1 and D respectively. Specifically, 1-8 g of decyl glucoside and 1-10 g of deionized water are mixed evenly to obtain standby mixed solution B1; 1-6 g of cocamidopropyl betaine, 0.1-1.2 g of sodium chloride and 2-15 g of deionized water are mixed evenly to obtain standby mixed solution B2; 1-4 g of disodium cocoamphodiacetate, 0.1-1.5 g of sodium chloride and 3-10 g of deionized water are mixed evenly to obtain standby mixed solution B3; 0.5-3 g of PEG-150 distearate is placed in a container and named as solution B4; 0.5-4 g of propylene glycol and 0.01-0.2 g of chlorhexidine diacetate are mixed evenly to obtain standby mixed solution C1; 10-20 g of deionized water and 1-2.5 g of sodium chloride are mixed evenly to obtain standby mixed solution D. At the same time, 0.1-0.65g of phenoxyethanol, 0.1-0.3g of propylene glycol, 0.05-0.3g of benzoic acid and 0.025-0.1g of glyceryl caprylate are mixed evenly to obtain a standby mixed solution E. Mixed solution A is added to the main pot, and B1, B2 and B3 are added in turn. The temperature is heated to 80-85°C and stirred evenly until it is uniform and transparent. Then, B4 is added to the main pot, heated to 80-85°C, stirred until it is uniform and transparent, and kept warm for 30-60min. Continue stirring at room temperature until the temperature drops to 45-50°C, add C1, and stir evenly. Continue stirring, slowly cool to 30-35°C, add E and D in turn, stir evenly, wait for cooling, and take samples from the main pot to send to the laboratory for inspection of appearance, odor, pH and other indicators. Ensure that the product meets the relevant quality standards and divide the product into small bottles and seal them. Ensure that the amount of product in each bottle is consistent and the bottles are well sealed to prevent product leakage or external contamination.

[0070] The above shows and describes the basic principles, main features and advantages of the present invention. It should be understood by those skilled in the art that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention to be protected. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A novel foaming antibacterial and antipruritic lotion, characterized in that: The composition includes the following raw materials: Phellodendron chinense, Stemona tuber, Cnidium monnieri, Sophora flavescens, Chrysanthemum indica, Epimedium, Polygonum cuspidatum, deionized water, decyl glucoside, cocamidopropyl betaine, sodium chloride, disodium cocoamphodiacetate, propylene glycol, PEG-150 distearate, phenoxyethanol, benzoic acid, glyceryl caprylate and chlorhexidine diacetate. The novel foaming antibacterial and antipruritic lotion preparation process comprises the following steps: (1) Preparation A. Add 1-3g of Phellodendron chinense, 1-3g of Stemona officinalis, 1-3g of Cnidium monnieri, 1-3g of Sophora flavescens, 1-3g of Chrysanthemum indici, 1-3g of Epimedium brevicornum, and 1-3g of Polygonum cuspidatum to an extraction tank and add 60-100g of deionized water, soak for 1 hour, heat, boil for 1 hour, and filter with 100 mesh coarse filtration and 400 mesh fine filtration after cooling to obtain a mixed solution A45-70g; B1, 1-8 g of decyl glucoside and 1-10 g of deionized water are mixed evenly to obtain a mixed solution B1 for standby use; B2, 1-6 g of cocamidopropyl betaine, 0.1-1.2 g of sodium chloride and 2-15 g of deionized water are mixed to obtain a standby mixed solution B2; B3, 1-4 g of disodium cocoamphoacetate, 0.1-1.5 g of sodium chloride and 3-10 g of deionized water are mixed to obtain a standby mixed solution B3; B4. Place 0.5-3 g of PEG-150 distearate in a container for later use; C1, 0.5-4 g of propylene glycol and 0.01-0.2 g of chlorhexidine diacetate are uniformly mixed to obtain a standby mixed solution C1; D. Mix 10-20 g of deionized water and 0.1-2.5 g of sodium chloride to obtain a mixed solution D for standby use; E. Evenly mix 0.1-0.65 g of phenoxyethanol, 0.1-0.3 g of propylene glycol, 0.05-0.3 g of benzoic acid and 0.025-0.1 g of glyceryl caprylate to obtain a mixed solution E for standby use. (2) Mixing Add A to the main pot, add B1, B2 and B3 in turn, heat to 80-85℃ and stir evenly until it is homogeneous and transparent; Add B4 to the main pot, heat to 80-85℃, stir until homogeneous and transparent, and keep warm for 30-60 minutes; Continue stirring at room temperature until the temperature drops to 45-50°C, add C1 and stir evenly; continue stirring, slowly cool to 30-35°C, add E and D in turn, stir evenly, and wait for cooling. (3) Submission for inspection Take samples and send them to the laboratory to test the appearance, smell, pH and other indicators. (4) Bottling Dispense the product into vials and seal them.