Application of gallocatechin gallate and isoquercitrin

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By using a composition of gallate and isoquercetin, gluconeogenesis in hepatocytes and promoting intracellular delivery of glucose, the problem of imbalance in blood glucose in diabetes is solved and significant blood glucose regulation effect is achieved.

CN119792322APending Publication Date: 2025-04-11AMOREPACIFIC CORP

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Patent Information

Application Number: CN202411415258.8
Authority / Receiving Office: CN · China
Patent Type: Applications(China)
Current Assignee / Owner
Priority Date: 2023-10-11
Filing Date: 2024-10-11
Publication Date: 2025-04-11

Application Information

Patent Timeline

11 Oct 2023

Priority

11 Oct 2024

Application

CN202411415258.8

11 Apr 2025

Publication

CN119792322A

IPC: A61K31/7048; A61K31/353; A61P3/10; A23L33/105

CPC: A61P3/08; A61K31/7048; A61K31/353; A61K31/7004; A61P3/10; A23L33/125; A23V2002/00; A23V2200/328

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Application Domain

Organic active ingredients Metabolism disorder

Technology Topics

Biotechnology Myocyte

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AI Technical Summary

Technical Problem

Diabetes is caused by disruption of the insulin signaling system, which leads to imbalance in blood sugar regulation. The prior art is difficult to effectively inhibit the occurrence of diabetes or improve symptoms.

Method used

Provided is a composition comprising gallocatechin Gallate (GCG) and isoquercitrin (IQC) to achieve effective regulation of blood glucose by inhibiting gluconeogenesis in hepatocytes and promoting glucose delivery in adipocytes and myocytes.

Benefits of technology

This composition significantly inhibits the expression of gluconeogenesis-related genes, promotes the intracellular absorption and delivery of glucose, significantly improves the efficacy of blood sugar regulation, and has excellent blood sugar regulation ability.

✦ Generated by Eureka AI based on patent content.

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Abstract

In the present specification, disclosed is a method for preparing a gallocatechin gallate (Gallocatable Gallate), which comprises the steps of: preparing a gallocatechin gallate (Gallocatable Gallate; the invention relates to application of a composition for regulating blood sugar or keeping healthy blood sugar values, in particular to application of a composition for regulating blood sugar or keeping healthy blood sugar values, such as GCG and isoquercitrin (IQC) and application of the composition to preparation of a composition for regulating blood sugar or keeping healthy blood sugar values. In one aspect, the composition of the present invention comprises a complex component of gallocatechin gallate and isoquercitrin, can effectively inhibit gluconeogenesis in hepatocytes, and can effectively improve glucose delivery in differentiated adipocytes and muscle cells, thus exhibiting excellent blood glucose regulation efficacy.

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