Specimen conformality fixing and sampling device for radical treatment of intestinal cancer

Abstract

The invention provides a conformal fixed sampling device for an intestinal cancer radical treatment specimen, and relates to the technical field of medical equipment. The device comprises a fixing device, the fixing device comprises a probe set, a motor set, a sensing system and a control processor. The probe group comprises a plurality of groups of conformal probes; part of motors in the motor set independently drive the corresponding conformal probes to be close to or away from the intestinal cancer radical treatment specimen; the sensing system comprises a plurality of sensors and a signal transmission device; and the bottom end of each group of conformal probes is correspondingly provided with the sensor. The device has the advantages that the advancing distance of the conformal probe and the contact pressure between the conformal probe and the surface of the intestinal cancer specimen are accurately controlled through components such as the motor set, the control processor, the conformal probe and the sensing system, good conformity and fixation of the intestinal cancer specimen are achieved, different intestinal cancer specimens can also be conformed, and therefore in the intestinal cancer specimen sampling process, the intestinal cancer specimen sampling efficiency is improved. And enough pathological tissue information is reserved while the intestinal cancer specimen is conformally fixed.

Description

Technical Field

[0001] The present invention relates to the technical field of medical equipment, and in particular to a conformal fixing and sampling device for radical treatment of intestinal cancer specimens. Background Art

[0002] Colon cancer radical specimens are common samples sent to the pathology department for examination. The sampling process requires manual operation by pathologists. Pathologists usually cut thicker tissue blocks first, and then use secondary thinning to reach the required thickness. Secondary thinning will cause obvious tissue loss and take a long time. There are also risks of instrument injury and prolonged exposure of doctors to formaldehyde. In order to solve these problems, the prior art has also proposed a device that uses a combination of multiple elastic parts to compress the specimen for fixation, and then uses a combination of blades with equal spacing (such as 0.3 cm) to cut the specimen.

[0003] Since the intestinal tissue of the human body is mostly uneven in structure, the pathological area of ​​the colorectal cancer specimen is generally large in size and irregular in shape. The elastic combination compression fixation method makes it difficult to control the contact force during the compression process to avoid causing a large deformation of the specimen. If the above method cannot ensure good conformity to the colorectal cancer specimen, it will lead to instability of the specimen during the slicing process, affect the tissue thickness of the slice, and even cause tissue damage during cutting, destroying the integrity of the pathological tissue information, which is not conducive to subsequent pathological diagnosis.

[0004] Based on this, the present application intends to propose a conformal fixation and sampling device for colorectal cancer radical specimens, which can solve the problem that the fixation devices in the prior art cannot conformally fix colorectal cancer specimens by well conforming to the shape of the colorectal cancer specimens. Summary of the invention

[0005] In view of the deficiencies of the prior art, the present invention provides a conformal fixation and sampling device for colorectal cancer radical specimens, which solves the problem that the fixation devices in the prior art cannot conformally fix colorectal cancer specimens.

[0006] To achieve the above objectives, the present invention is implemented through the following technical solutions:

[0007] The invention provides a conformal fixation and sampling device for radical treatment of intestinal cancer, comprising a fixation device;

[0008] The fixture includes a probe group, a motor group, a sensor system, and a control processor;

[0009] The probe set includes multiple sets of conformal probes;

[0010] Some motors in the motor group independently drive the corresponding conformal probe to approach and move away from the colon cancer radical specimen;

[0011] The sensing system includes a plurality of sensors and a signal transmission device. The bottom end of each group of conformal probes is provided with a corresponding sensor, and the signal transmission device is electrically connected with the sensor and the control processor.

[0012] In a preferred embodiment, the device further comprises a material taking blade, the material taking blade and the conformal probe are evenly spaced apart, and the material taking blade is driven by another part of the motor group.

[0013] In a preferred embodiment, the conformable probe is a cylindrical structure with a hollow interior, and the sensor is a pressure sensor.

[0014] In a preferred embodiment, the device further comprises a backing plate, a top surface of which is provided with a plurality of parallel grooves, and the positions of the grooves are adapted to the positions of the material taking blades.

[0015] In one embodiment, the device further includes a box body and a formaldehyde suction device, and the box body is provided with the formaldehyde suction device.

[0016] In a preferred embodiment, a gas sensor is provided at the air suction port of the formaldehyde suction device.

[0017] In one embodiment, the device further comprises a fault alarm device, and the fault alarm device is electrically connected to the fixing device.

[0018] In one embodiment, the device further comprises a material taking blade cleaning device, and the material taking blade cleaning device is electrically connected to the fixing device.

[0019] In one embodiment, the device further comprises a control panel connected to the fixing device.

[0020] In one embodiment, the device further comprises a sewage pipe.

[0021] The present invention provides a conformal fixation sampling device for radical treatment of intestinal cancer. Compared with the prior art, it has the following beneficial effects:

[0022] Through the use of components such as sampling blades, motor groups, control processors, conformal probes, sensors, and signal transmission devices, when slicing and sampling colorectal cancer specimens, multiple groups of conformal probes, driven by the motor groups, can approach and contact the colorectal cancer specimens. At this time, the sensors fixed at the bottom of the conformal probes contact the surface of the specimen, and the signal transmission device can receive data sent back by the sensors, and transmit signals to the motor group through the control processor to accurately control the contact pressure between the conformal probes and the surface of the colorectal cancer specimens, thereby avoiding the conformal probes from crushing the specimens while maintaining a firm limit on the colorectal cancer specimens. Through precise control of the different travel distances of the multiple groups of probes, the multiple groups of conformal probes can automatically adjust the travel distances according to the shapes of different colorectal cancer specimens, thereby achieving good conformity and fixation of the colorectal cancer specimens, thereby avoiding the movement of the colorectal cancer specimens during the cutting process, thereby achieving the fixation of the colorectal cancer specimens while retaining sufficient lesion tissue information during the sampling process of the colorectal cancer specimens. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0024] Figure 1 A stereoscopic diagram of a fixing device of a conformal fixing and sampling device for radical treatment of intestinal cancer provided by the present invention;

[0025] Figure 2 A schematic diagram of the structure of a sampling blade of a conformal fixed sampling device for radical resection of intestinal cancer provided in an embodiment of the present invention;

[0026] Figure 3 A schematic diagram of the cross-sectional structure of a conformal probe of a conformal fixation sampling device for radical treatment of intestinal cancer provided by the present invention;

[0027] Figure 4 A schematic diagram of the backing plate structure of a conformal fixation sampling device for radical treatment of intestinal cancer provided by the present invention;

[0028] Figure 5 A schematic diagram of the position of a formaldehyde suction device of a conformal fixation sampling device for radical treatment of intestinal cancer provided by the present invention;

[0029] Figure 6 A schematic diagram of the position of a fault alarm device of a conformal fixed sampling device for radical treatment of intestinal cancer provided by the present invention;

[0030] Figure 7 A schematic structural diagram of a cleaning device for a sampling blade of a conformal fixed sampling device for radical specimen removal of intestinal cancer provided by the present invention;

[0031] Figure 8 A schematic diagram of the control panel structure of a conformal fixed sampling device for radical treatment of colorectal cancer provided by the present invention;

[0032] Fig. 9 A schematic diagram of the position of a sewage pipe of a conformal fixed sampling device for radical treatment of intestinal cancer provided by the present invention;

[0033] In the figure:

[0034] 1. Fixing device; 2. Pad; 3. Formaldehyde suction device; 4. Fault alarm device; 5. Material blade cleaning device; 6. Control panel; 7. Sewage pipe;

[0035] 11. Conformal probe; 12. Motor group; 13. Sensor; 14. Control processor; 15. Material extraction blade; 21. Groove. DETAILED DESCRIPTION

[0036] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention are clearly and completely described. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0037] The embodiment of the present application solves the problem in the prior art that the intestinal cancer radical treatment specimen fixation device cannot conformally fix the intestinal cancer specimen by providing a conformal fixation and sampling device for intestinal cancer radical treatment specimens, thereby achieving good conformity to the shape of the intestinal cancer specimen, thereby ensuring sufficient retention of the diseased tissue information during the process of slicing and sampling the intestinal cancer specimens.

[0038] The technical solution in the embodiment of the present application is to solve the above technical problems, and the overall idea is as follows:

[0039] Colon cancer radical specimens are common specimens sent to the pathology department. The sampling process requires manual operation by pathologists, which requires high proficiency of pathologists and accuracy of tissue cutting. Whether the tissue block is successfully collected directly affects the accuracy of the next pathological diagnosis. The current pathological sampling specification stipulates that the size of the tissue block is usually 2.0cm×2.0cm×0.3cm. Therefore, the ideal slice thickness of colon cancer radical specimens should be 0.3cm. However, it is difficult to ensure that a 0.3cm thick tissue block is successfully cut in one go by manual slicing. Therefore, pathologists generally cut thicker tissue blocks (such as 0.5cm) first, and then use secondary thinning to reach a thickness of 0.3cm. This can not only reduce the risk of sharp injury, but also ensure the flatness and integrity of the slices, which is conducive to the retention and presentation of lesion tissue information. However, there are also obvious shortcomings. Secondary thinning will cause obvious tissue loss, which is inconsistent with ensuring the flatness and integrity of the tissue in order to retain enough lesion tissue information.

[0040] In order to solve the many shortcomings of the manual sampling method for colorectal cancer radical specimens, achieve uniform tissue thickness, short sampling time, small tissue loss, low risk of sharp instrument injury, and avoid prolonged exposure of doctors to formaldehyde, improvements should be made in specimen fixation and cutting:

[0041] (1) What kind of fixation device or method should be selected to replace manual labor to achieve precise fixation of specimens? (2) How to achieve one-time synchronous and precise cutting of specimens? The necessary prerequisite for precise cutting is to achieve accurate and firm specimen fixation. One-time synchronous cutting is relatively easy to achieve, so the design of the fixation device or method must reach or approach the conformity of the specimen to the human hand. Borrowing the term "conformal radiotherapy" in medical radiotherapy, "conformity" refers to adjusting the shape of the radiation beam to make it fit the shape of the tumor as closely as possible, thereby reducing damage to surrounding healthy tissues. "Conformity" in this application refers to the degree of match between the device for fixing the tumor and the shape of the tumor. Therefore, designing a fixed sampling device that can be highly conformal to the colorectal cancer radical specimen and has a sensitive sensing system on the contact surface with the specimen has become an effective solution to the shortcomings of manual sampling.

[0042] In order to better understand the above technical solution, the above technical solution will be described in detail below in conjunction with the accompanying drawings and specific implementation methods.

[0043] Example 1

[0044] See also Figure 1As shown, a conformal fixation sampling device for colorectal cancer radical specimens proposed in this embodiment includes a fixing device; the fixing device includes a probe group 11, a motor group 12, a sensor system and a control processor 14; the probe group 11 includes a plurality of groups of conformal probes 11; some motors in the motor group 12 independently drive the corresponding conformal probes 11 to approach or move away from the colorectal cancer radical specimens; the sensor system includes a plurality of sensors 13 and a signal transmission device, a sensor 13 is correspondingly arranged at the bottom end of each group of conformal probes 11, and the signal transmission device is electrically connected to the sensor 13 and the control processor 14. It should be noted that: when fixing the colorectal cancer specimen, some motors in the motor group 12 independently drive the corresponding conformal probes 11 to compress the colorectal cancer specimen for fixation. Each group of conformal probes 11 is controlled by the motor group 12 and can approach and contact the colorectal cancer specimen. At this time, the sensor 13 fixed at the bottom of the conformal probe 11 contacts the surface of the specimen, and the signal transmission device can receive the data sent back by the sensor 13, and transmit the signal to the motor group 12 through the control processor 14 to stop the movement of the conformal probe 11, thereby achieving precise control of the different travel distances of multiple groups of conformal probes 11, so that multiple groups of conformal probes 11 can automatically adjust the travel distance according to the shape of different colorectal cancer specimens; at the same time, the sensor 13 can also accurately control the contact pressure between the conformal probe 11 and the surface of the colorectal cancer specimen to be consistent, avoiding the conformal probe 11 from crushing the specimen while maintaining a firm limit on the colorectal cancer specimen, achieving good conformity and fixation of the colorectal cancer specimen, and can also conform to different colorectal cancer specimens.

[0045] See also Figure 2 As shown, in a preferred embodiment, the above-mentioned conformal fixed sampling device for radical treatment of colorectal cancer specimens also includes a sampling blade 15, and the sampling blade 15 and the conformal probe 11 are evenly spaced, that is, the sampling blade 15 is arranged between two adjacent conformal probes 11, or the conformal probe 11 is arranged between two adjacent sampling blades 15. The sampling blade 15 is driven by another part of the motor in the motor group 12 except for driving the conformal probe 11. It should be noted that: the sampling blade 15 is uniformly driven by another part of the motor of the motor group 12 for cutting, which can ensure the flatness and integrity of the cut surface when the colorectal cancer specimen is cut; the intervals of the sampling blades 15 are fixed, between 0.15cm-0.45cm, and more preferably, the sampling blades 15 are arranged at equal intervals of 0.3cm, and this thickness meets the pathological sampling specifications.

[0046] See also Figure 3As shown, in a preferred embodiment, the conformal probe 11 is a hollow cylindrical structure, and the sensor 13 is embedded in one end of the cylindrical structure close to the colorectal cancer specimen. More preferably, the sensor 13 is a pressure sensor. It should be noted that the conformal probe 11 is a hollow cylindrical structure, and the wire connecting the sensor 13 to the signal transmission device and the control processor 14 is placed inside the conformal probe 11, which is convenient for the device user to arrange the internal circuits of the device, and the space utilization rate is high.

[0047] See also Figure 4 As shown, in a preferred embodiment, the device further comprises a pad 2, and a plurality of parallel grooves 21 are provided on the top surface of the pad 2, and the position of the grooves 21 matches the position of the sampling blades 15, that is, each sampling blade 15 falls into the corresponding groove 21 below it after falling. It should be noted that the position of the groove 21 matches the position of the sampling blade 15, and after the sampling blade 15 cuts through the colon cancer specimen, the sampling blade 15 enters the groove 21 to avoid direct contact with the pad 2 to cause wear, thereby increasing the service life of the sampling blade 15.

[0048] Example 2

[0049] See also Figure 5 As shown, the conformal fixation sampling device for radical treatment of colorectal cancer specimens proposed in this embodiment also includes a box body and a formaldehyde suction device 3, and the formaldehyde suction device 3 is arranged in the box body.

[0050] In a preferred embodiment, a gas sensor is provided at the air suction port of the above-mentioned formaldehyde suction device 3. It should be noted that: when the colorectal cancer sample is placed in the box for the fixation sampling process, the formaldehyde suction device 3 can absorb the formaldehyde gas volatilized from the surface of the sample during the process (from the formalin solution used to preserve the sample), thereby protecting the staff of the pathology department and reducing environmental pollution; the gas sensor is used to monitor whether there is formaldehyde gas at the air suction port and issue a corresponding instruction to drive the formaldehyde suction device 3 to work.

[0051] Example 3

[0052] See also Figure 6 As shown, the conformal fixation sampling device for radical treatment of colorectal cancer specimens proposed in this embodiment also includes a fault alarm device 4, which is electrically connected to the fixing device. It should be noted that the fault alarm device 4 is electrically connected to the sensor system and the motor group 12 in the fixing device, and the fault alarm device 4 can monitor the data of the sensor 13 and control the motor group 12. When a fault occurs, the motor group 12 is controlled to shut down to prevent the conformal probe 11 or the sampling blade 15 from damaging the colorectal cancer specimen.

[0053] Example 4

[0054] See also Figure 7As shown, the conformal fixed sampling device for colorectal cancer radical specimens proposed in this embodiment also includes a sampling blade cleaning device 5, which is electrically connected to the fixing device. It should be noted that the sampling blade cleaning device 5 is an external water pipe, a cleaning device with an electromagnetic valve and multiple nozzles, and the sampling blade cleaning device 5 is electrically connected to the control processor 14, and can clean the sampling blade 15 after the colorectal cancer specimen is cut and sampled.

[0055] Example 5

[0056] See also Figure 8 As shown, the conformal fixation sampling device for colorectal cancer radical specimens proposed in this embodiment also includes a control panel 6 and a device in any one of the above embodiments 2-4, and the control panel 6 is electrically connected to the fixing device. It should be noted that: the control panel 6 is electrically connected to the control processor 14, and the pathology staff can interact with the fixing device through the control panel 6, and further, interact with any of the devices in the above embodiments 2-4 to avoid direct contact with the colorectal cancer specimens during the sampling process.

[0057] Example 6

[0058] See also Fig. 9 As shown, the conformal fixation sampling device for radical treatment of colorectal cancer provided in this embodiment also includes a sewage pipe 7. It should be noted that the sewage pipe 7 can remove pollutants generated during the sample cutting process to protect the staff of the pathology department.

[0059] The implementation process of the above embodiment of the present invention is described in detail below in combination with the explanation of the specific steps:

[0060] When the colorectal cancer sample cutting and sampling begins, the pathologist places the colorectal cancer sample on the top of the pad 2, and starts the sampling and cutting through the control panel 6. The motor group 12 first drives the multiple groups of conformal probes 11 to move from top to bottom until they contact the surface of the colorectal cancer sample. The sensor 13 is fixedly installed at the bottom of the conformal probe 11. The sensor can determine whether the bottom of the conformal probe 11 contacts the colorectal cancer sample and accurately feeds back data to the control processor 14, which controls the motor group 12 to stop the movement of the conformal probe 11, completes the good conformity of the colorectal cancer sample, and fixes the colorectal cancer sample; then, the motor group 12 will drive the sampling blade 15 to cut the colorectal cancer sample from top to bottom, and cut the colorectal cancer sample into thin slices of the required thickness. By controlling the processor 14 to drive the motor group 12, the sampling can be controlled. The distance that the sampling blade 15 travels is determined until the sampling blade 15 falls into the groove 21, thereby preventing the sampling blade 15 from being damaged by collision. The pathologist then takes out the colorectal cancer specimen after cutting and sampling. The pathologist can also control the sampling blade cleaning device 5 to clean the sampling blade 15 through the control panel 6. The pollutants generated during the sample cutting process and after the sampling blade 15 is cleaned are discharged through the sewage pipe 7. The formaldehyde suction device 3 can monitor the formaldehyde gas concentration through the gas sensor and automatically extract the formaldehyde (formalin solution) gas volatilized from the surface of the colorectal cancer specimen during the sampling process. The fault alarm device 4 can monitor the data of the sensor 13 and control the motor group 12. When a fault occurs, the motor group 12 is controlled to shut down to prevent the conformal probe 11 or the sampling blade 15 from damaging the colorectal cancer specimen.

[0061] In summary, compared with the prior art, the present invention has the following beneficial effects:

[0062] 1. Through the cooperation of conformal probe, motor group, control processor, sensor and signal transmission device, the colorectal cancer specimen can be well conformed and fixed; the sampling blade is uniformly driven by the motor to cut, which can ensure the flatness and integrity of the cut surface when the colorectal cancer specimen is cut; the interval of the sampling blade is fixed, which conforms to the pathological sampling standards; thus, in the process of sampling colorectal cancer specimens, the colorectal cancer specimens can be fixed while retaining sufficient pathological tissue information.

[0063] 2. Through the arrangement of the above-mentioned components and the formaldehyde suction device, the sampling blade cleaning device, the control panel, the sewage pipe, and the sealing strip, the pathology staff is prevented from contacting the colorectal cancer specimens and the sampling blades during the sampling process of colorectal cancer specimens. The pollutants generated during the sample cutting process and after the sampling blades are cleaned, thereby protecting the pathology staff from the risk of sharp instrument injury and formaldehyde exposure.

[0064] 3. By setting up a fault alarm device, when a fault occurs, the motor group can be controlled to shut down, thereby preventing the conformal probe or sampling blade from damaging the colorectal cancer specimen.

[0065] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the sentence "comprise a ..." do not exclude the presence of other identical elements in the process, method, article or device including the elements.

[0066] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit the same. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that the technical solutions described in the aforementioned embodiments may still be modified, or some of the technical features may be replaced by equivalents. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A conformal fixation and sampling device for radical treatment of colorectal cancer, characterized in that: The device comprises a fixing device (1); The fixing device (1) comprises a probe group, a motor group (12), a sensor system and a control processor (14); The probe set includes multiple sets of conformal probes (11); Some of the motors in the motor group (12) independently drive each corresponding group of the conformal probes (11) to move closer to or farther away from the colon cancer radical specimen; The sensing system comprises a plurality of sensors (13) and a signal transmission device. The bottom end of each group of conformal probes (11) is provided with the corresponding sensor (13). The signal transmission device is electrically connected to the sensor (13) and the control processor (14).

2. The conformal fixation and sampling device for radical resection of colorectal cancer as claimed in claim 1, characterized in that: The device further comprises: a material taking blade (15), wherein the material taking blade (15) and the conformal probe (11) are evenly spaced and distributed, and the material taking blade (15) is driven by another part of the motors in the motor group (12).

3. The conformal fixation and sampling device for radical resection of colorectal cancer as claimed in claim 1, characterized in that: The conformable probe (11) is a cylindrical structure with a hollow interior, and the sensor (13) is a pressure sensor.

4. The conformal fixation and sampling device for radical resection of colorectal cancer as claimed in claim 1, characterized in that: The device also comprises a backing plate (2), the top surface of which is provided with a plurality of parallel grooves (21), the positions of the grooves (21) being adapted to the positions of the material taking blades (15).

5. A conformal fixation and sampling device for colorectal cancer radical specimens according to any one of claims 1 to 4, characterized in that: The device further comprises a box body and a formaldehyde suction device (3), wherein the box body is provided with the formaldehyde suction device (3).

6. The conformal fixation and sampling device for radical resection of intestinal cancer as claimed in claim 5, characterized in that: A gas sensor is provided at the air suction port of the formaldehyde suction device (3), and the gas sensor is used to monitor whether formaldehyde gas exists at the air suction port.

7. A conformal fixation and sampling device for radical resection of colorectal cancer as claimed in any one of claims 1 to 5, characterized in that: The device further comprises a fault alarm device (4), wherein the fault alarm device (4) is electrically connected to the fixing device (1).

8. A conformal fixation and sampling device for colorectal cancer radical specimen collection as claimed in any one of claims 1 to 7, characterized in that: The device further comprises a material taking blade cleaning device (5), and the material taking blade cleaning device (5) is electrically connected to the fixing device (1).

9. A conformal fixation and sampling device for colorectal cancer radical specimen collection as claimed in any one of claims 1 to 8, characterized in that: The device further comprises a control panel (6), wherein the control panel (6) is electrically connected to the fixing device (1).

10. A conformal fixation and sampling device for radical resection of colorectal cancer as claimed in any one of claims 1 to 9, characterized in that: The device also includes a sewage discharge pipe (7).

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