Electrode slice temperature detection method and alternating current signal application method for tumor treatment

Abstract

The invention provides an electrode slice temperature detection method and an alternating current signal application method for tumor treatment. According to the method, a direct-current electric signal is transmitted to a dual-purpose signal line of an electrode plate, and grounding wires are sequentially conducted in a time-sharing manner, so that temperature detection signals detected by temperature sensors are acquired line by line. The dual-purpose signal wire and the grounding wire of the electrode plate are controlled in a combined mode to collect the temperature detection signals detected by the temperature sensors, the temperature can be comprehensively and accurately monitored, the number of conductive traces is effectively reduced, and efficient and accurate electrode plate control is achieved. In addition, alternating current electric signals applied to the dielectric elements of the electrode plate can be controlled or adjusted according to the collected temperature detection signals, low-temperature scalding can be avoided, and the use safety of the electrode plate is improved.

Description

Technical Field

[0001] This application relates to the technology of Tumor Treating Fields (TTF), and particularly to a method for detecting the temperature of an electrode patch and a method for applying an alternating current signal for tumor treatment. Background Art

[0002] Tumor Treating Fields is a method that inhibits the formation of spindle microtubules during the mitosis of certain tumor cells through low-intensity medium-high frequency alternating electric fields, thereby inhibiting the separation of intracellular organelles during the cell division phase and inducing apoptosis of cells in the mitosis phase, so as to achieve the purpose of treating tumors.

[0003] Compared with traditional cancer treatment methods, TTF has an innovative mechanism of action. Some physiological characteristics of tumor cells, such as geometric shape and high-frequency mitosis, make them vulnerable to TTF. TTF disrupts the normal aggregation of tubulin by applying a directional force on intracellular polar particles (such as macromolecules and organelles). These processes may lead to physical damage to the cell membrane and apoptosis. At the end of cell mitosis, the structural morphology of the cleavage furrow causes uneven electric field distribution around it. At the same time, under the influence of TTF, the electric field intensity at the cleavage furrow is significantly enhanced, and charged substances in the cell move towards the cleavage furrow, interfering with or even destroying the formation of the cell structure, and ultimately leading to the failure of cell division and apoptosis.

[0004] In existing tumor electric field treatment systems, an electric field generating device is used to transmit an alternating current signal for tumor electric field treatment to an electrode patch, and then an alternating electric field is applied to the tumor site of the patient through the electrode patch for tumor electric field treatment. When the tumor treatment electric field is applied to the patient's body, heat will accumulate at the electrode patch attachment site, and the temperature of the electrode patch attachment site will also increase accordingly. Therefore, it is necessary to continuously monitor the temperature at the electrode patch attachment site. When the monitored temperature rises to a certain preset value, it is necessary to timely adjust the electric field intensity applied to the tumor site of the patient to avoid scalding the patient's skin due to excessive temperature at the electrode patch attachment site.

[0005] The tumor electro - field therapy system includes at least a pair of electrode patches. There are multiple electrode units in each electrode patch. Even if the same alternating - current signal is applied to each electrode unit, the heat generated on each electrode unit will vary due to its different positions. That is, the temperatures of each electrode unit on the entire electrode patch will not be exactly the same. In this way, it is possible that the temperatures of some electrode units in the entire electrode patch exceed the preset temperature while the temperatures of other electrode units are normal. In order to ensure that there is a sufficient application time in tumor electro - field therapy while avoiding causing low - temperature burns on the patient's body surface, it is necessary to implement individual control for the over - temperature electrode units. However, for existing electrode patches, implementing individual control for electrode units requires setting a conductive trace for each electrode unit in the substrate of the electrode patch. This will increase the number of conductive traces in the electrode - patch substrate, making the electrode patch difficult to bend, and the cable electrically connected to the electrode patch will also thicken, increasing the overall weight of the electrode patch, which is not conducive to the application of the electrode patch.

[0006] Therefore, it is necessary to provide an electrode - patch temperature - detection method that uses fewer conductive traces to perform zonal control on multiple electrode units. Summary of the Invention

[0007] The purpose of this application is to provide an electrode - patch temperature - detection method and an alternating - current signal application method for tumor electro - field therapy to solve or eliminate problems in related technologies.

[0008] To achieve the above object, the present application provides the following technical solution: An electrode sheet temperature detection method is applied to an electrode sheet that applies an alternating current signal to inhibit tumor growth or inhibit mitosis of cancer cells to a tumor site or a tumor tissue culture. The electrode sheet includes: a plurality of dielectric elements for applying an alternating current signal; a plurality of temperature sensors for detecting the temperature at corresponding parts of the corresponding dielectric elements, the plurality of temperature sensors are respectively arranged in one-to-one correspondence with the plurality of dielectric elements and are configured as a plurality of row groups and a plurality of column groups in electrical connection; a plurality of ground wires, respectively corresponding to the plurality of row groups one by one, and each ground wire is configured to short-circuit and ground the ground terminals of the temperature sensors in the corresponding row group; and a plurality of dual-purpose signal lines, respectively corresponding to the plurality of column groups one by one, and each dual-purpose signal line is simultaneously connected to the signal terminals of the temperature sensors in the corresponding column group and the corresponding dielectric elements in the corresponding column group and switches between transmitting a direct current signal to the temperature sensors in the corresponding column group to collect temperature detection signals and transmitting an alternating current signal to the dielectric elements in the corresponding column group for tumor treatment; the method includes: transmitting a direct current signal to the plurality of dual-purpose signal lines of the electrode sheet; and sequentially and time-divisionally turning on each ground wire of the electrode sheet to collect the temperature detection signals detected by the temperature sensors in each row group of the corresponding electrode sheet row by row; or transmitting a direct current signal to any one of the dual-purpose signal lines in the electrode sheet; and sequentially and time-divisionally turning on each ground wire of the electrode sheet to collect the temperature detection signals detected by the temperature sensors in the corresponding column group one by one.

[0009] Further, transmitting a direct current signal to the plurality of or any one of the dual-purpose signal lines of the electrode sheet is performed after stopping the application of the alternating current signal to the electrode sheet.

[0010] Further, stopping the application of the alternating current signal to the electrode sheet is achieved by stopping transmitting the alternating current signal to each of the dual-purpose signal lines.

[0011] Further, each of the ground wires is disconnected when the dual-purpose signal line transmits an alternating current signal to the dielectric elements in the corresponding column group for tumor treatment.

[0012] Further, the plurality of ground wires are sequentially and time-divisionally closed when the dual-purpose signal line transmits a direct current signal to the temperature sensors in the corresponding column group to collect temperature detection signals, and only one of the ground wires is turned on at the same time, and the rest of the ground wires are all disconnected.

[0013] Further, the method further includes: converting the collected temperature detection signals to obtain respective digital temperature signals; and determining the temperature at the corresponding parts of the respective dielectric elements based on the respective digital temperature signals.

[0014] Further, each ground wire is electrically connected to a grounding switch, and each dual-purpose signal wire is electrically connected to a bidirectional switching switch. The temperature detection signals collected from the temperature sensors are obtained by combining the control of the grounding switches and the bidirectional switching switches.

[0015] Further, the switching between transmitting a DC signal to each temperature sensor in the corresponding column group to collect temperature detection signals and transmitting an AC signal to each dielectric element in the corresponding column group for tumor treatment of the dual-purpose signal wire is achieved by combining the control of the corresponding bidirectional switching switch and each grounding switch.

[0016] Further, the bidirectional switching switch has a fixed end electrically connected to the corresponding dual-purpose signal wire, a collection end that conducts with the fixed end to transmit a DC signal, and an input end that conducts with the fixed end to transmit an AC signal. When the dual-purpose signal wire electrically connected to it transmits an AC signal, the fixed end and the input end of the bidirectional switching switch are conducted, or when the dual-purpose signal wire electrically connected to it transmits a DC signal, the fixed end and its collection end are conducted.

[0017] The present application also provides an AC signal application method for tumor electric field therapy, which controls or adjusts the AC signals applied to the dielectric elements of the electrode plate according to the temperature detection signals obtained by the above method.

[0018] The above description is only an overview of the technical solution of the present application. In order to be able to understand the technical means of the present application more clearly, it can be implemented according to the content of the specification. And in order to make the above and other purposes, features and advantages of the present application more obvious and understandable, the following specifically gives the specific embodiments of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic framework diagram of a tumor electric field therapy system according to an embodiment of the present application, in which a schematic structural diagram of an electrode plate of the first embodiment is shown;

[0020] Figure 2 For use in the present application Figure 1 It is a schematic structural diagram of a transformation embodiment of the electrode plate of the first embodiment of the tumor electric field therapy system shown in the present application;

[0021] Figure 3 For the present application Figure 1 It is a schematic circuit connection diagram of the tumor electric field system shown in the present application, which shows Figure 1 The electrode plate of the first embodiment shown in Figure 2 Or the circuit connection diagram of the electrode plate of the variation embodiment shown in Figure 1 And the adapter of the first embodiment shown in

[0022] Figure 4 Schematic block diagram of the internal structure of the adapter shown in this application Figure 3 ;

[0023] Figure 5 Schematic block diagram of the internal structure of the electric field generator of the tumor electric field therapy system shown in this application Figure 1 ;

[0024] Figure 6 Similar to Figure 3 , the circuit connection diagram of the tumor electric field therapy system according to the second embodiment of this application, which shows the circuit connection diagram of the electrode patch for the second embodiment of the tumor electric field therapy system of this application and Figure 3 the adapter shown;

[0025] Figure 7 Similar to Figure 3 , the circuit connection diagram of the tumor electric field therapy system according to the third embodiment of this application, which shows the circuit connection diagram of the electrode patch for the third embodiment of the tumor electric field therapy system of this application and Figure 3 the adapter shown;

[0026] Figure 8 Similar to Figure 3 , the circuit connection diagram of the tumor electric field therapy system according to the fourth embodiment of this application, which shows the circuit connection diagram of the electrode patch for the fourth embodiment of the tumor electric field therapy system of this application and Figure 3 the adapter shown;

[0027] Figure 9 Similar to Figure 1 , the framework diagram of the tumor electric field therapy system according to the fifth embodiment of this application, which shows the structural diagram of the electrode patch of the fifth embodiment;

[0028] Figure 10 (A) is Figure 9 the structural diagram of a transformed embodiment of the electrode patch for the fifth embodiment of the tumor electric field therapy system shown in this application;

[0029] Figure 10 (B) is similar to Figure 10 (A), and is Figure 9 the structural diagram of another transformed embodiment of the electrode patch for the fifth embodiment of the tumor electric field therapy system shown in this application;

[0030] Figure 11 Similar to Figure 3 , and is Figure 9 a circuit connection diagram of the tumor electric field therapy system shown, which shows Figure 9 the electrode patch of the fifth embodiment shown or Figure 10(A), Figure 10 The circuit connection schematic diagram of the electrode sheet of the transformation embodiment shown in Figure 3 and the adapter shown in;

[0031] Figure 12 Similar to Figure 11 This is the circuit connection schematic diagram of the tumor electric field therapy system of the sixth embodiment of the present application, which shows Figure 9 The electrode sheet of the fifth embodiment shown in or Figure 10 (A), Figure 10 (B) The electrode sheet of the transformation embodiment shown in and Figure 3 Another circuit connection schematic diagram of the adapter shown in;

[0032] Figure 13 Similar to Figure 12 This is the circuit connection schematic diagram of the tumor electric field therapy system of the seventh embodiment of the present application, which shows Figure 9 The electrode sheet of the fifth embodiment shown in or Figure 10 (A), Figure 10 (B) The electrode sheet of the transformation embodiment shown in and Figure 3 Another circuit connection schematic diagram of the adapter shown in;

[0033] Figure 14 Similar to Figure 12 This is the circuit connection schematic diagram of the tumor electric field therapy system of the eighth embodiment of the present application, which shows Figure 9 The electrode sheet of the fifth embodiment shown in or Figure 10 (A), Figure 10 (B) The electrode sheet of the transformation embodiment shown in and Figure 3 Another circuit connection schematic diagram of the adapter shown in;

[0034] Figure 15 Similar to Figure 1 This is the framework schematic diagram of the tumor electric field therapy system of the ninth embodiment of the present application, which shows the structural schematic diagram of the electrode sheet of the ninth embodiment;

[0035] Figure 16 This is Figure 15 The circuit connection schematic diagram of the tumor electric field therapy system shown in, which shows Figure 15 The electrode sheet of the ninth embodiment shown in and Figure 3 The circuit connection schematic diagram of the adapter shown in;

[0036] Figure 17 Similar to Figure 16 This is the circuit connection schematic diagram of the tumor electric field therapy system of the tenth embodiment of the present application, which shows Figure 15 The electrode sheet of the ninth embodiment shown in and Figure 3Another circuit connection schematic diagram of the adapter shown;

[0037] Figure 18 Similar to Figure 3 This is a circuit connection schematic diagram of the tumor electric field therapy system according to the eleventh embodiment of the present application, which shows Figure 1 the electrode patch of the first embodiment shown or Figure 2 a circuit connection schematic diagram of the electrode patch of the variant embodiment shown in

[0038] Figure 19 Similar to Figure 6 This is a circuit connection schematic diagram of the tumor electric field therapy system according to the twelfth embodiment of the present application, which shows Figure 6 a circuit connection schematic diagram of another variant embodiment of the electrode patch shown and the adapter of the second embodiment;

[0039] Figure 20 It is Figure 18 and Figure 19 a schematic block diagram of the internal structure of the adapter for the second embodiment of the tumor electric field therapy system of the present application shown in

[0040] Figure 21 This is a circuit connection schematic diagram of the tumor electric field therapy system according to the thirteenth embodiment of the present application, which shows a circuit connection schematic diagram of the electrode patch for the thirteenth embodiment of the tumor electric field therapy system of the present application and the adapter of the third embodiment;

[0041] Figure 22 This is a circuit connection schematic diagram of the tumor electric field therapy system according to the fourteenth embodiment of the present application, which shows Figure 7 a circuit connection schematic diagram of a variant embodiment of the electrode patch described and the adapter of the third embodiment;

[0042] Figure 23 It is Figure 21 and Figure 22 a schematic block diagram of the internal structure of the adapter for the third embodiment of the tumor electric field therapy system of the present application shown in

[0043] Figure 24 This is a circuit connection schematic diagram of the tumor electric field therapy system according to another embodiment of the present application, which shows Figure 11 a circuit connection schematic diagram of the electrode patch shown and the adapter of the fourth embodiment;

[0044] Figure 25 This is a circuit connection schematic diagram of another tumor electric field therapy system of the present application, which shows Figure 12 a circuit connection schematic diagram of the electrode patch shown and the adapter of the fourth embodiment;

[0045] Figure 26For Figure 24 and Figure 25 A schematic block diagram of the internal structure of the adapter for the fourth embodiment of the tumor electric field therapy system of the present application as shown in

[0046] Figure 27 A schematic diagram of the circuit connection of the tumor electric field therapy system according to another embodiment of the present application, which shows Figure 13 A schematic diagram of the circuit connection of the electrode patch shown and the adapter of the fifth embodiment;

[0047] Figure 28 A schematic diagram of the circuit connection of the tumor electric field therapy system according to another embodiment of the present application, which shows Figure 14 A schematic diagram of the circuit connection of the electrode patch shown and the adapter of the fifth embodiment;

[0048] Figure 29 For the present application Figure 27 and Figure 28 A schematic block diagram of the internal structure of the adapter for the fifth embodiment of the tumor electric field therapy system of the present application as shown in

[0049] Figure 30 A schematic diagram of the circuit connection of the tumor electric field therapy system according to another embodiment of the present application, which shows Figure 16 A schematic diagram of the circuit connection of the electrode patch shown and the adapter of the sixth embodiment;

[0050] Figure 31 For Figure 30 A schematic block diagram of the internal structure of the adapter for the sixth embodiment of the tumor electric field therapy system of the present application as shown in

[0051] Figure 32 A schematic diagram of the circuit connection of the tumor electric field therapy system according to another embodiment of the present application, which shows Figure 17 A schematic diagram of the circuit connection of the electrode patch shown and the adapter of the seventh embodiment;

[0052] Figure 33 For Figure 32 A schematic block diagram of the internal structure of the adapter for the seventh embodiment of the tumor electric field therapy system of the present application as shown in

[0053] Figure 34 A schematic flowchart of the temperature detection method for the tumor electric field therapy system according to an embodiment of the present application;

[0054] Figure 35 A schematic flowchart of the alternating current signal application control method for tumor electric field therapy according to an embodiment of the present application;

[0055] Figure 36 A schematic flowchart of the signal control method for tumor electric field therapy according to an embodiment of the present application;

[0056] Figure 37 Schematic flow chart of the electrode sheet temperature detection method according to another embodiment of the present application;

[0057] Figure 38 Schematic flow chart of the alternating current signal application method for tumor electrotherapy according to another embodiment of the present application;

[0058] Figure 39 Schematic flow chart of the alternating current signal application method based on the temperature detection signal according to an embodiment of the present application;

[0059] Figure 40 Schematic flow chart of the alternating current signal application method based on the temperature detection signal according to another embodiment of the present application.

[0060] Description of reference numerals:

[0061] Tumor electric field therapy systems 100, 100D, 100G, electrode patches 10, 10’, 10A, 10B, 10C, 10D, 10D’, 10D”, 10E, 10F, 10G, 10H, 10J, 10K, 10L, 10M, 10N, flexible printed circuit boards 11, 11A, 11B, 11C, 11D, 11E, 11F, 11G, 11H, 11J, 11K, 11L, 11M, 11N, connection parts 111, 111’, wiring parts 112, 112’, bridging parts 113, 113’, main trunks 114, branches 115, electrode units 12, 12-1, 12-2, 12-3, 12-4, 12-5, 12-6, 12-7, 12-8, 12-9, 12-10, 12-11, 12-12, 12-13, 12-14, 12-15, 12-16, 12-17, 12-18, 12-19, 12-20, first cables 13, 13’, 13D, 13D’, 13D”, 13H, temperature sensors 14, ground terminals 14-1, signal terminals 14-2, dielectric elements 15, diodes 16, ground wires 18, first ground wires 18-1, second ground wires 18-2, third ground wires 18-3, fourth ground wires 18-4, fifth ground wires 18-5, dual-purpose signal wires 19, first dual-purpose signal wires 19-1, second dual-purpose signal wires 19-2, third dual-purpose signal wires 19-3, fourth dual-purpose signal wires 19-4, fifth dual-purpose signal wires 19-5, sixth dual-purpose signal wires 19-6, adapters 20, 20K, 20M, 20B, 20C, 20D, 20E, second cables 21, first controllers 22, analog-to-digital converters 23, voltage-dividing resistors 24, ground switches 25, first ground switches 25-1, second ground switches 25-2, third ground switches 25-3, fourth ground switches 25-4, fifth ground switches 25-5, bidirectional switching switches 26, first bidirectional switching switches 26-1, second bidirectional switching switches 26-2, third bidirectional switching switches 26-3, fourth bidirectional switching switches 26-4, fifth bidirectional switching switches 26-5, sixth bidirectional switching switches 26-6, first communication units 27, AC signal wires 28, first power modules 29, electric field generators 30, second power modules 31, second controllers 32, second communication units 33, AC signal generators 34, AC signal switches 35, first AC signal switches 35-1, second AC signal switches 35-2, third AC signal switches 35-3, fourth AC signal switches 35-4, AC signal wirings 36, first AC signal wirings 36-1, second AC signal wirings 36-2, third AC signal wirings 36-3, fourth AC signal wirings 36-4, first connectors 40, 40A, 40B, 40C, 40D, 40E, 40F, 40G, 40H, 40J, 40K, 40L, 40M, 40D’, 40E’, 40F’, 40G’40H’, the first plugs 41, 41’, 41D, 41D’, 41D”, 41H, the first socket 42, the second connector 50, the second plug 51, and the second socket 52. Detailed implementation

[0062] The embodiments of the technical solutions of the present application will be described in detail below with reference to the accompanying drawings. The following embodiments are only used to illustrate the technical solutions of the present application more clearly, so they are only examples and cannot be used to limit the protection scope of the present application.

[0063] Figure 1 Shown is a schematic diagram of a tumor electrotherapy system 100 according to an embodiment of the present application. As Figure 1 shown, the tumor electrotherapy system 100 includes: at least a pair of electrode patches 10, an adapter 20 electrically connected to the electrode patches 10, and an electric field generator 30 electrically connected to the adapter 20. The electric field generator 30 generates an alternating current signal for tumor treatment and applies the alternating current signal to the electrode patches 10 through the adapter 20 to generate a treatment electric field between the paired electrode patches 10. The adapter 20 is electrically connected between the electrode patches 10 and the electric field generator 30 and is used to deliver the alternating current signal generated by the electric field generator 30 to the electrode patches 10. That is to say, the electric field generator 30 can generate an alternating current signal, and the generated alternating current signal is transmitted to each electrode patch 10 through the adapter 20, so as to generate a treatment electric field for treating tumors between the same pair of electrode patches 10.

[0064] As Figure 1 shown, in this embodiment, the number of electrode patches 10 is 4. From the perspective of spatial structure arrangement, each electrode patch 10 includes a plurality of electrode units 12 that are both axially symmetrically arranged and centrally symmetrically arranged and have the same number, a plurality of connecting parts 111 located between adjacent two electrode units 12, a bridging part 113 erected between adjacent two connecting parts 111, a wiring part 112 connected to the bridging part 113, and a first cable 13 connected to the wiring part 112. The bridging part 113 and the wiring part 112 are arranged perpendicular to each other to form a "T" shape. The bridging part 113 is erected between adjacent two connecting parts 111. Each electrode unit 12 of the electrode patch 10 is electrically connected to the adapter 20 through the first cable 13.

[0065] Each electrode unit 12 has a temperature sensor 14 and a dielectric element 15. The temperature sensor 14 is used to detect the temperature at which the electrode unit 12 is attached to the patient's body surface part. It can be a thermistor element or other temperature sensors other than thermistors, and can be set at any position on the electrode unit 12. The dielectric element 15 is used to apply an alternating current signal to the patient's tumor part. The dielectric element 15 can be a dielectric ceramic sheet or a polymer dielectric layer composed of a polymer material. In this embodiment, each dielectric element 15 has a through hole (not labeled) in the middle for accommodating a corresponding temperature sensor 14. Each electrode unit 12 may further include a diode 16 connected in series with the temperature sensor 14, which can prevent the reverse inflow of current to prevent the detection signal from other electrode units 12 from affecting the temperature sensor 14. The ground terminal 14-1 of the temperature sensor 14 is connected in series with the anode of the diode 16 and is grounded through the cathode of the diode 16.

[0066] The electrode unit 12 applies an alternating current signal through the dielectric element 15 in the first mode; in the second mode, it detects or collects the temperature of the patient's body surface where the corresponding electrode unit 12 is attached through the temperature sensor 14; in the third mode, it stops applying the alternating current signal and stops temperature detection and collection. The first mode, the second mode, and the third mode do not overlap in time periods. That is, the time period when the dielectric element 15 of the electrode unit 12 applies an alternating current signal is staggered and does not overlap with the time period when the temperature sensor 14 detects the temperature. The electrode unit 12 can cycle between applying an alternating current signal through its dielectric element 15 and detecting the temperature through its temperature sensor 14, that is, the electrode unit 12 can cycle between the first mode and the second mode. The electrode unit 12 can also cycle between the first mode, the second mode, and the third mode, that is, the electrode unit 12 cycles among applying an alternating current signal through the dielectric element 15, collecting or detecting the temperature through the temperature sensor 14, and stopping applying the alternating current signal and temperature collection.

[0067] Each electrode sheet 10 includes an electrode array (not labeled) composed of 20 electrode units 12. The electrode array (not labeled) also has a flexible circuit board 11 including a connection part 111, a wiring part 112, and a bridging part 113. The 20 electrode units 12 are all arranged at intervals in the electrode array (not labeled) arranged in four rows and six columns. Specifically, four electrode units 12 are arranged in each of the first row and the last row, and six electrode units 12 are arranged in each of the middle two rows. The four electrode units 12 in the first row are respectively located in the second to fifth columns, the six electrode units 12 in each of the middle two rows are respectively located in the first to sixth columns, and the four electrode units 12 in the last row are also respectively located in the second to fifth columns.

[0068] The connecting part 111 is only located between two adjacent electrode units 12 arranged in the column direction in each of the third column and the fourth column, and between the other two adjacent electrode units 12 adjacent in the row direction in each row but excluding the two electrode units 12 in the third column and the fourth column in each row. That is, between two adjacent electrode units 12 in the third column and the fourth column, they are only connected in the column direction by the connecting part 111, and are all in a disconnected state and not connected by the connecting part 111 in the row direction; the electrode units 12 in each of the first column, the second column, the fifth column, and the sixth column are only connected to the electrode units 12 adjacent to them in the row direction by the connecting part 111 arranged horizontally, and are all in a disconnected state between them in the column direction and the adjacent electrode units 12. That is to say, between two column - adjacent electrode units 12 in each of the first column, the second column, the fifth column, and the sixth column, they are all in a disconnected state.

[0069] The electrode unit 12 in the third column and the connecting part 111 arranged longitudinally between the electrode units 12 in this column, and the electrode unit 12 in the fourth column and the connecting part 111 also arranged longitudinally between the electrode units 12 in this column together constitute the main trunk 114 of the electrode array (not labeled). The connecting parts 111 located on the opposite sides of the two - column electrode units 12 in the third column and the fourth column and respectively connected to the electrode units 12 in the third column and the fourth column through the horizontally arranged connecting parts 111, and the electrode units 12 connected to the horizontally arranged connecting parts 111 together constitute the branches 115 of the electrode array (not labeled). That is to say, in this embodiment, the electrode array (not labeled) includes two main trunks 114 and several branches 115 respectively extending laterally from the two main trunks 114. Each branch 115 has a free end far from the main trunk 114, and the free ends of adjacent branches 115 are all in a disconnected state, and the positions and distances between adjacent branches 115 can be freely adjusted according to the actual usage scenario requirements. Specifically, one main trunk 114 is composed of the electrode units 12 in the third column and the connecting parts 111 arranged longitudinally between the adjacent electrode units 12 in this column, and the other main trunk 114 is composed of the electrode units 12 in the fourth column and the connecting parts 111 arranged longitudinally between the adjacent electrode units 12 in this column. The remaining electrode units 12 connected to the main trunk 114 through the horizontally arranged connecting parts 111 and the horizontally arranged connecting parts 111 are all branches 115.

[0070] Specifically, the several branches 115 are respectively: a connecting portion 111 that extends laterally to the left from the electrode unit 12 in the first row of the third column and is located in the first row, and an electrode unit 12 that is connected to the connecting portion 111 and is located in the second column of the first row; two connecting portions 111 that extend laterally to the left from the electrode unit 12 in the second row of the third column and are located in the second row, and two electrode units 12 that are located in the first column and the second column of the second row; two connecting portions 111 that extend laterally to the left from the electrode unit 12 in the third row of the third column and are located in the third row, and two electrode units 12 that are located in the first column and the second column of the third row; a connecting portion 111 that extends laterally to the left from the electrode unit 12 in the fourth row of the third column and is located in the fourth row, and an electrode unit 12 that is located in the second column of the fourth row; a connecting portion 111 that extends laterally to the right from the electrode unit 12 in the first row of the fourth column and is located in the first row, and an electrode unit 12 that is located in the fifth column of the first row; two connecting portions 111 that extend laterally to the right from the electrode unit 12 in the second row of the fourth column and are located in the second row, and two electrode units 12 that are located in the fifth column and the sixth column of the second row; two connecting portions 111 that extend laterally to the right from the electrode unit 12 in the third row of the fourth column and are located in the third row, and two electrode units 12 that are located in the fifth column and the sixth column of the third row; a connecting portion 111 that extends laterally to the right from the electrode unit 12 in the fourth row of the fourth column and is located in the fourth row, and an electrode unit 12 that is located in the fifth column of the fourth row.

[0071] The electrode array (not labeled) is divided into a symmetric left side portion including the left three columns and a right side portion including the right three columns, and the left side portion and the right side portion are only connected by the bridging portion 113. The left side portion is composed of a main trunk 114 located in the third column and several branches 115 that extend laterally to the left from the main trunk 114. The right side portion is composed of a main trunk 114 located in the fourth column and several branches 115 that extend laterally to the right from the main trunk 114. The two main trunks 114 are connected by the bridging portion 113 erected between them. Specifically, the two main trunks 114 are electrically connected by the bridging portion 113 erected between the connecting portion 111 connecting the electrode unit 12 in the second row of the third column and the electrode unit 12 in the third row of the third column and the connecting portion 111 connecting the electrode unit 12 in the second row of the fourth column and the electrode unit 12 in the third row of the fourth column. The connecting portion 111 connecting the electrode unit 12 in the second row of the third column and the electrode unit 12 in the third row of the third column, the connecting portion 111 connecting the electrode unit 12 in the second row of the fourth column and the electrode unit 12 in the third row of the fourth column, and the bridging portion 113 are arranged in a substantially "H" shape. In other embodiments, the bridging portion 113 may also be erected between an electrode unit 12 located in the third column and an electrode unit 12 located in the fourth column. Optionally, the bridging portion 113 is erected between two electrode units 12 that are adjacent in the row direction and are located in the third column and the fourth column.

[0072] According to their positions in the electrode array (not labeled), each electrode unit 12 can be divided into the electrode units 12 located at the periphery and the electrode units 12 located at the center. The electrode units 12 located at the periphery include four electrode units 12 in the first row, two electrode units 12 at the opposite ends of the second row, two electrode units 12 at the opposite ends of the third row, and four electrode units 12 in the fourth row. The electrode units 12 located at the center include four electrode units 12 in the middle of the second row and four electrode units 12 in the middle of the third row. Among the multiple electrode units 12 located at the periphery, some adjacent two electrode units 12 are connected by a horizontally arranged connecting portion 111, and some adjacent two electrode units 12 are arranged in a disconnected state. Among the multiple electrode units 12 located at the periphery, the adjacent two electrode units 12 connected by the connecting portion 111 are some row-adjacent two electrode units 12. Specifically, among the multiple electrode units 12 located at the periphery, the two column-adjacent and diagonally adjacent electrode units 12 are all arranged in a disconnected state; some row-adjacent two electrode units 12 are also arranged in a disconnected state; only some row-adjacent two electrode units 12 are connected by a horizontally extending connecting portion 111. Among the multiple electrode units 12 located at the center, only the column-adjacent two electrode units 12 on the main trunk 114 are connected by a vertically arranged connecting portion 111, and only the row-adjacent two electrode units 12 on the branch 115 are connected by a horizontally arranged connecting portion 111.

[0073] The electrode array (not labeled) also has intervals (not labeled) formed between several spaced-apart electrode units 12, which can allow the moisture on the patient's body surface to escape, enable heat exchange between the patient's body surface skin and the outside world, or allow the patient's body surface skin to breathe freely, and also allow the branches 115 to freely adjust their positions and spacings, and can also avoid wrinkles when the electrode patch 10 is applied. The intervals (not labeled) include a first interval D1 between the two main trunks 114 and a second interval D2 between the branches 115. The first interval D1 is located between the third-column electrode unit 12 and the fourth-column electrode unit 12, and the second interval D2 is located between the electrode units 12 in adjacent rows. That is, in the row direction, the electrode unit 12 in the third column and the adjacent electrode unit 12 in the fourth column are disconnected, and no connecting portion 111 is provided but the aforementioned first interval D1 is formed; and in the column direction, only the two column-adjacent electrode units 12 in the third column and the fourth column are connected by the connecting portion 111, and the two column-adjacent electrode units 12 in each of the other four columns are not connected by the connecting portion 111 but form the aforementioned second interval D2. The settings of the first and second intervals D1 and D2 can also increase the freedom of some electrode units 12 and can also avoid wrinkles when attaching the electrode patch 10.

[0074] In some other embodiments, the tumor treating electric field system 100 may also have more or fewer electrode patches 10. In some other embodiments, each pair of electrode patches 10 has the same number of electrode units 12, and different pairs of electrode patches 10 may also have different numbers of electrode units 12. In some other embodiments, the 20 electrode units 12 may also be arranged in other ways. Of course, in some other embodiments, the electrode patches 10 may also have other numbers of electrode units 12. In short, the implementation of the present application is not limited by the number and arrangement form of the electrode units 12 of the electrode patches 10.

[0075] Figure 2 The illustrated electrode patch 10' is Figure 1 a variant embodiment of the electrode patch 10 shown in. The spatial structure of the electrode patch 10' is the same as that of the electrode patch 10, and it also includes a plurality of electrode units 12' arranged at intervals, a number of connecting portions 111' located between two adjacent electrode units 12', a wiring portion 112' connected to the bridging portion 113', a first cable 13' connected to the wiring portion 112', a first interval D1 formed between the third column of electrode units 12' and the fourth column of electrode units 12', and a second interval D2' formed between adjacent rows of electrode units 12'; the difference is only that: two column - adjacent electrode units 12' in the fourth column are both in a disconnected state and not connected by a longitudinally arranged connecting portion 111', but two column - adjacent electrode units 12' in the fifth column are connected by a longitudinally arranged connecting portion 111', and each electrode unit 12' in the fourth column is connected to a row - adjacent electrode unit 12' in the fifth column by a laterally arranged connecting portion 111'; and the bridging portion 113' is connected between two electrode units 12' located in the third row and the third column and the third row and the fourth column.

[0076] Figure 3 is Figure 1 a schematic circuit connection diagram of the first embodiment of the electrode patch 10 for the tumor treating electric field system 100 or its variant embodiment electrode patch 10' and the adapter 20 of the first embodiment. It should be noted that: Figure 3 The arrangement of the illustrated electrode units 12 is for more clearly showing the electrical connection situation between an electrode patch 10 and the adapter 20, Figure 3 The arrangement of the illustrated electrode units 12 does not represent the arrangement of the electrode units 12 in the spatial structure. The following takes the electrode patch 10 in the first embodiment as an example for circuit connection description. Combining Figure 1 and Figure 3, the flexible printed circuit board 11 is embedded with multiple conductive traces 18, 19. The multiple conductive traces 18, 19 include multiple ground lines 18 and multiple dual-purpose signal lines 19. The first cable 13 has multi-core wires (not shown) that are respectively and electrically connected to the multiple ground lines 18 and the multiple dual-purpose signal lines 19 of the flexible printed circuit board 11 in a one-to-one correspondence. The total number of the ground lines 18 and the dual-purpose signal lines 19 embedded in the flexible printed circuit board 11 does not exceed 10. Therefore, the number of wires of the first cable 13 does not exceed 10.

[0077] In this embodiment, each electrode plate 10 is provided with 20 electrode units 12. The 20 electrode units 12 are sorted and grouped in the order of 1 to 20 in terms of circuit connection, and are divided into four row groups and five column groups, that is, the 20 electrode units 12 are arranged in four rows and five columns in terms of circuit connection. The temperature sensor 14 of each electrode unit 12 includes a ground terminal 14-1 and a signal terminal 14-2. The dielectric element 15 and the temperature sensor 14 of each electrode unit 12 are both welded to the flexible printed circuit board 11, and each dielectric element 15 is short-circuited with the signal terminal 14-2 of the corresponding temperature sensor 14. Since the electrode units 12 are arranged in four rows and five columns in terms of circuit connection, and each electrode unit includes a corresponding dielectric element 15 and a corresponding temperature sensor 14, therefore, the multiple temperature sensors 14 are also arranged in four row groups and five column groups in terms of circuit connection, and the multiple dielectric elements 15 are also arranged in four row groups and five column groups in terms of circuit connection. It should be noted that this arrangement method is to more clearly show the electrical connection situation between the electrode plate 10 and the adapter 20, and does not represent the arrangement of the electrode units 12 in the spatial structure. Its spatial structure may be a structure that is roughly in an array as Figure 1 shown, or other structures, such as petal-shaped or scattered-shaped, etc., which can be regular or irregular structures. The dielectric element 15 is configured to apply an alternating electric field to the tumor site of the patient. The temperature sensor 14 is configured to detect the temperature of the patient's body surface in contact with the electrode plate 10 and output a temperature detection signal to the adapter 20. In this embodiment, the multiple dual-purpose signal lines 19 of the flexible printed circuit board 11 are respectively and correspondingly arranged with multiple column groups of the electrode units 12, and are configured to transmit the alternating current signal generated by the electric field generator 30 to the dielectric element 15 in each electrode unit 12 of the corresponding column group. That is, the dielectric elements 15 located in the same column group are all short-circuited through the same dual-purpose signal line 19 of the flexible printed circuit board 11, and the dielectric elements 15 located in different column groups are respectively connected in parallel through different dual-purpose signal lines 19 of the flexible printed circuit board 11. The dual-purpose signal lines 19 of the flexible printed circuit board 11 are respectively and electrically connected to the corresponding wires in the first cable 13, and then are electrically connected to the electric field generator 30 through the adapter 20. That is, the dual-purpose signal lines 19 of the flexible printed circuit board 11 receive the alternating current signal generated by the electric field generator 30 through the first cable 13 and the adapter 20.

[0078] The multiple ground wires 18 are respectively arranged in one-to-one correspondence with multiple row groups of the electrode units 12, and the multiple ground wires 18 are respectively used to sequentially short-circuit the temperature sensors 14 of the corresponding electrode units 12 in each row group to the ground. That is, the ground terminals 14-1 of the multiple temperature sensors 14 in the same row group are all short-circuited through the same ground wire 18 of the flexible circuit board 11, and the ground terminals 14-1 of the temperature sensors 14 in different row groups are respectively connected to the ground in parallel through different ground wires 18 of the flexible circuit board 11. During the time period of temperature detection or in the second mode, only one of the multiple ground wires 18 is conducting at the same moment, and the rest are disconnected.

[0079] Each of the multiple multi-purpose signal lines 19 is also configured to respectively transmit a direct current signal to the temperature sensors 14 in each electrode unit 12 in the corresponding column group to collect and transmit the detected temperature signal. The signal terminals 14-2 of the multiple temperature sensors 14 in different column groups are respectively connected in parallel through different multi-purpose signal lines 19 of the flexible circuit board 11, and the signal terminals 14-2 of the multiple temperature sensors 14 in the same column group are all short-circuited to the same multi-purpose signal line 19 of the flexible circuit board 11. Specifically, each multi-purpose signal line 19 is configured to short-circuit the signal terminal 14-2 of the temperature sensor 14 of at most one electrode unit 12 in each row group to an external device for receiving the detection signal. Among them, the signal terminals 14-2 of the temperature sensors 14 connected by each multi-purpose signal line 19 are different from each other to avoid the subsequent output of repeated signals by the multi-purpose signal line 19. That is, when the number of electrode units 12 in a certain row group is the same as the number of multi-purpose signal lines 19, each multi-purpose signal line 19 is respectively electrically connected to the signal terminal 14-2 of the temperature sensor 14 of a different one of the electrode units 12 in this row group; when the number of electrode units 12 in a certain row group is less than the number of multi-purpose signal lines 19, there is at least one multi-purpose signal line 19 that is not electrically connected to the signal terminal 14-2 of the temperature sensor 14 of the electrode unit 12, and the remaining each multi-purpose signal line 19 is respectively electrically connected to the signal terminal 14-2 of the temperature sensor 14 of a different one of the electrode units 12 in this row group. In this embodiment, the external device for receiving the detection signal is the adapter 20. The multi-purpose signal line 19 of the flexible circuit board 11 receives a direct current signal from the adapter 20 or the electric field generator 30 through the first cable 13, and transmits the collected or detected temperature signal to the adapter 20, and then transmits it to the electric field generator 30 through the adapter 20.

[0080] In this embodiment, when a temperature sensor 14 is configured in each electrode unit 12 for temperature detection, the number of wires of the first cable 13 is reduced through the above circuit design, avoiding the cable from becoming thicker and the softness of the cable from becoming harder, which increases the difficulty of cable fixing; at the same time, it is avoided that the increase in the number of wires of the first cable 13 affects the adhesion effect between the electrode patch 10 and the corresponding body surface of the patient's tumor site. The ground wire 18 and the dual-purpose signal wire 19 embedded in the flexible printed circuit board 11 are a total of 9 circuits. Specifically, in this embodiment, the ground wire 18 embedded in the flexible printed circuit board 11 is 4 circuits, and the dual-purpose signal wire 19 is 5 circuits. In other embodiments, the number of circuits of the ground wire 18 and the dual-purpose signal wire 19 embedded in the flexible printed circuit board 11 may also have other numbers according to the circuit layout and quantity difference of the electrode units 12 in different electrode patches, which will be specifically described in subsequent embodiments.

[0081] In the tumor electric field therapy system 100, the number of conductive circuits electrically connected to the ground wire 18 is related to the number of row groups M of the electrode units 12, and it can be greater than or equal to the number of row groups of the electrode units 12, where M is a positive integer. In the tumor electric field therapy system 100, the number of conductive circuits electrically connected to the dual-purpose signal wire 19 is related to the number of column groups N of the electrode units 12, and it can be greater than or equal to the number of column groups of the electrode units 12, where N is a positive integer. The number of circuits L embedded in the flexible printed circuit board 11 of the electrode patch 10 is equal to the sum of the number of the ground wire 18 and the number of the dual-purpose signal wire 19. In this embodiment, the number of the ground wire 18 is equal to the number of row groups M of the electrode units 12; the dual-purpose signal wire 19 is equal to the number of column groups N of the electrode units 12.

[0082] In Figure 3In the illustrated embodiment, the electrode sheet 10 includes four ground wires 18, and each ground wire 18 is used to ground the ground terminals 14-1 of the temperature sensors 14 in the same row group. The four ground wires 18 of the electrode sheet 10 are respectively a first ground wire 18-1, a second ground wire 18-2, a third ground wire 18-3, and a fourth ground wire 18-4. Among the four row groups of the electrode sheet 10, the first row group includes electrode units 12-1 to 12-5, the second row group includes electrode units 12-6 to 12-10, the third row group includes electrode units 12-11 to 12-15, and the fourth row group includes electrode units 12-16 to 12-20. Specifically, the first ground wire 18-1 is used to ground the electrode units 12-1 to 12-5 in the first row group; the second ground wire 18-2 is used to ground the electrode units 12-6 to 12-10 in the second row group; the third ground wire 18-3 is used to ground the electrode units 12-11 to 12-15 in the third row group; and the fourth ground wire 18-4 is used to ground the electrode units 12-16 to 12-20 in the fourth row group. It should be noted that these ground wires 18 can be selectively closed or opened, which can be achieved by connecting each ground wire 18 in series with a switch, and this will be described in detail below. The above "grounding the electrode unit 12" may refer to grounding the ground terminal 14-1 of the temperature sensor 14 in the electrode unit 12, or may refer to connecting the diode 16 in series with the temperature sensor 14 of the same electrode unit 12 and grounding them together. In short, each ground wire 18 shorts and grounds the ground terminals 14-1 of the temperature sensors 14 of all the electrode units 12 in each row group.

[0083] Continue to refer to Figure 3As shown in the figure, the electrode sheet 10 of this embodiment further includes five two-purpose signal lines 19. One end of each two-purpose signal line 19 is respectively connected to all the electrode units 12 in each column group, and the other end is connected to an adapter 20 for receiving temperature detection signals and transmitting alternating current signals. That is to say, for each row group, each two-purpose signal line 19 can be selectively connected to one of the electrode units 12 or not connected to any of the electrode units 12 in that row group to avoid duplicate signals being output by the two-purpose signal line 19 subsequently. Specifically, the five two-purpose signal lines 19 of the electrode sheet 10 include a first two-purpose signal line 19-1, a second two-purpose signal line 19-2, a third two-purpose signal line 19-3, a fourth two-purpose signal line 19-4, and a fifth two-purpose signal line 19-5. One end of the first two-purpose signal line 19-1 is respectively and simultaneously connected to the dielectric elements 15 and the signal ends 14-2 of the temperature sensors 14 of the four electrode units 12, namely the electrode unit 12-1, the electrode unit 12-6, the electrode unit 12-11, and the electrode unit 12-16; one end of the second two-purpose signal line 19-2 is respectively and simultaneously connected to the dielectric elements 15 and the signal ends 14-2 of the temperature sensors 14 of the four electrode units 12, namely the electrode unit 12-2, the electrode unit 12-7, the electrode unit 12-12, and the electrode unit 12-17; one end of the third two-purpose signal line 19-3 is respectively and simultaneously connected to the dielectric elements 15 and the signal ends 14-2 of the temperature sensors 14 of the four electrode units 12, namely the electrode unit 12-3, the electrode unit 12-8, the electrode unit 12-13, and the electrode unit 12-18; one end of the fourth two-purpose signal line 19-4 is respectively and simultaneously connected to the dielectric elements 15 and the signal ends 14-2 of the temperature sensors 14 of the four electrode units 12, namely the electrode unit 12-4, the electrode unit 12-9, the electrode unit 12-14, and the electrode unit 12-19; one end of the fifth two-purpose signal line 19-5 is respectively connected to the dielectric elements 15 and the signal ends 14-2 of the temperature sensors 14 of the four electrode units 12, namely the electrode unit 12-5, the electrode unit 12-10, the electrode unit 12-15, and the electrode unit 12-20. In short, each two-purpose signal line 19 short-circuits in parallel the dielectric elements 15 and the signal ends 14-2 of the temperature sensors 14 of the respective electrode units 12 in the same column group and is used to connect to an external device. It should be noted that these two-purpose signal lines 19 can selectively transmit alternating current signals or receive temperature detection signals, which can be achieved by respectively connecting each two-purpose signal line 19 in series with a bidirectional switch 26 and coordinating the closing or opening of the ground wire 18, which will be described in detail below.

[0084] The multi-path ground wires 18 and the multi-path dual-purpose signal wires 19 are both conductive traces embedded in the flexible printed circuit board 11. The flexible printed circuit board 11 is electrically connected to the first cable 13. The multi-path ground wires 18 and the multi-path dual-purpose signal wires 19 embedded in the flexible printed circuit board 11 are respectively and electrically connected to corresponding wires (not shown) in the first cable 13 one by one.

[0085] The tumor electric field treatment system 100 of this embodiment includes at least a pair of the above-mentioned electrode plates 10, an adapter 20 electrically connected to the electrode plates 10, and an electric field generator 30 electrically connected to the adapter 20. The adapter 20 is connected between the electrode plates 10 and the electric field generator 30. The electric field generator 30 supplies an alternating current signal or supplies a direct current signal to the dielectric elements 15 in the plurality of electrode units 12 of the electrode plates 10 via the dual-purpose signal wires 19 of the adapter 20 and the electrode plates 10, and is used to receive the temperature detection signals output by the temperature sensors 14 in the plurality of electrode units 12. The adapter 20 is configured to deliver the alternating current signal generated by the electric field generator 30 to the dual-purpose signal wires 19 of the electrode plates 10, and is further configured to transmit a direct current signal to the dual-purpose signal wires 19 of the electrode plates and receive the temperature detection signals output by the multi-path dual-purpose signal wires 19 of the electrode plates 10.

[0086] Reference Figure 3 and Figure 4As shown, the adapter 20 includes: a first controller 22, multiple groups of analog-to-digital converters 23 connected to the first controller 22, multiple groups of voltage dividing resistors 24 corresponding to the multiple groups of analog-to-digital converters 23 one by one, multiple groups of ground switches 25 and multiple groups of bidirectional switching switches 26, a first communication unit 27, multiple AC signal lines 28 respectively connected to the multiple groups of bidirectional switching switches 26 one by one, and a first power module 29 connected to the first communication unit 27, the first controller 22, and the multiple groups of analog-to-digital converters 23 at the same time. The first power module 29 provides a DC power supply VCC for each electronic component of the adapter 20. The adapter 20 also includes multiple circuit lines (not labeled). Among them, the multiple circuit lines (not labeled) are respectively electrically connected to the multiple ground wires 18 and the multiple dual-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode piece 10 through the first cable 13 of the corresponding electrode piece 10. The multiple circuit lines (not labeled) include multiple AC signal lines 28 that respectively transmit AC signal to the corresponding electrode piece 10 and are electrically connected to the multiple dual-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode piece 10, multiple circuit lines (not labeled) that are respectively electrically connected to the multiple dual-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode piece 10 one by one and are used to supply power to each temperature sensor 14 of the electrode piece 10 or transmit the temperature detection signal of the electrode piece 10, and multiple circuit lines (not labeled) that are respectively electrically connected to the multiple ground wires 18 in the flexible circuit board 11 of the corresponding electrode piece 10 one by one. The number P of circuit lines of the adapter 20 electrically connected to one electrode piece 10 is equal to the sum of the number of rows M and the number of columns N of the electrode unit 12 of the electrode piece 10 plus 1; the number H of circuits of the adapter 20 electrically connected to X electrode pieces 10 is equal to X times the number of circuit lines of it electrically connected to a single electrode piece 10, that is, H = XP = X*(M + N + 1). The number of groups of the ground switches 25 and the number of groups of the bidirectional switching switches 26 are both related to the number of the electrode pieces 10. The number of groups of the ground switches 25 is the same as the number of groups of the bidirectional switching switches 26; and is not less than the number of the electrode pieces 10. Preferably, the number of groups of the ground switches 25 and the bidirectional switching switches 26 are both the same as the number of the electrode pieces 10. The following only takes the electrical connection between an electrode piece 10 with 20 electrode units 12 and the adapter 20 as an example for detailed description.

[0087] Each group of ground switches 25 is provided with multiple ground switches 25. The multiple ground switches 25 are respectively connected into the adapter 20 and are respectively electrically connected to the circuit lines (not labeled) corresponding to the multiple ground wires 18 of the corresponding one electrode piece 10, and are configured to control the conduction or disconnection of the multiple ground wires 18. The circuit lines (not labeled) respectively and electrically connecting the multiple ground wires 18 of the electrode piece 10 are grounded at one end close to the ground switch 25. The number of ground switches 25 in each group of ground switches 25 is related to the number of ground wires 18 of the flexible circuit board 11 of the corresponding electrode piece 10, and the two are equal in this embodiment. AsFigure 3 As shown, in this embodiment, each group of grounding switches 25 has a plurality of grounding switches 25, which is 4 in this embodiment, namely the first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3 and the fourth grounding switch 25-4. Each of the plurality of grounding switches 25 in each group respectively controls the closing or opening of the corresponding grounding wire 18 of a corresponding electrode plate 10. Specifically, the first grounding switch 25-1 is used to control the closing or opening of the first grounding wire 18-1 of the corresponding electrode plate 10, and then can cooperate with the corresponding group of bidirectional switching switches 26 to control the power-on and power-off of each temperature sensor 14 of the five electrode units 12 from the electrode unit 12-1 to the electrode unit 12-5 in the first row group of the electrode plate 10; the second grounding switch 25-2 is used to control the closing or opening of the second grounding wire 18-2 of the electrode plate 10, and then can cooperate with the corresponding group of bidirectional switching switches 26 to control the power-on and power-off of each temperature sensor 14 of the five electrode units 12 from the electrode unit 12-6 to the electrode unit 12-10 in the second row group of the electrode plate 10; the third grounding switch 25-3 is used to control the closing or opening of the third grounding wire 18-3 of the electrode plate 10, and then can cooperate with the corresponding group of bidirectional switching switches 26 to control the power-on and power-off of each temperature sensor 14 of the five electrode units 12 from the electrode unit 12-11 to the electrode unit 12-15 in the third row group of the electrode plate 10; the fourth grounding switch 25-4 is used to control the closing or opening of the fourth grounding wire 18-4 of the electrode plate 10, and then can cooperate with the corresponding group of bidirectional switching switches 26 to control the power-on and power-off of each temperature sensor 14 of the five electrode units 12 from the electrode unit 12-16 to the electrode unit 12-20 in the fourth row group of the electrode plate 10. The above-mentioned grounding switch 25 can be a mechanical switch, such as a relay. The grounding switch 25 can also be an electronic switch, and each grounding switch 25 can be opened and closed through the first controller 22 of the adapter 20.

[0088] In this embodiment, multiple groups of grounding switches 25 are all electronic switches. The first controller 22 is communicatively connected to multiple groups of grounding switches 25, and is used to sequentially and cyclically control the opening and closing states of the multiple grounding switches 25 in each group of grounding switches 25, and then sequentially and separately conduct each grounding wire 18 of the multiple grounding wires 18 of the corresponding electrode plate 10 and cooperate with the switching of the corresponding bidirectional switching switch 26 to sequentially and time-divisionally collect the temperatures of the patient's body surface detected by all the temperature sensors 14 on the electrode plate 10. The number of each group of grounding switches 25 is greater than or equal to the number of the grounding wires 18 of the flexible circuit board 11 of the corresponding electrode plate 10. In this embodiment, the number of each group of grounding switches 25 is the same as the number of the grounding wires 18 of the corresponding electrode plate 10.

[0089] Each group of bidirectional switching switches 26 is provided with a plurality of bidirectional switching switches 26. The plurality of bidirectional switching switches 26 in each group are respectively connected into the adapter 20 and are respectively electrically connected to circuit lines (not labeled) corresponding one-to-one to the multi-purpose signal lines 19 of a corresponding electrode plate 10. The number of bidirectional switching switches 26 in each group of bidirectional switching switches 26 is related to the number of multi-purpose signal lines 19 of the flexible circuit board 11 of the corresponding electrode plate 10, and is greater than or equal to the number of multi-purpose signal lines 19 of the flexible circuit board 11 of the corresponding electrode plate 10. In Figure 3 the illustrated embodiment, the two are equal. Each bidirectional switching switch 26 has two ends 1 and 2. The collection ends 1 of the plurality of bidirectional switching switches 26 in the same group are respectively electrically connected one-to-one to the corresponding detection channels among the plurality of detection channels of a corresponding group of analog-to-digital converters 23. The input ends 2 of each bidirectional switching switch 26 in the same group are electrically connected to the corresponding same AC signal line 28. Each bidirectional switching switch 26 is configured to control the multi-purpose signal line 19 to access the corresponding AC signal line 28 to transmit an alternating current signal or to access the corresponding detection channel of the corresponding group of analog-to-digital converters 23 to receive the temperature detection signal output by the temperature sensor 14.

[0090] Such as Figure 3As shown, taking the electrical connection between an electrode sheet 10 and an adapter 20 as an example, in this embodiment with 20 electrode units 12, the multiple bidirectional switching switches 26 are respectively the first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5. Multiple bidirectional switching switches 26 in the same group respectively control the switching between the corresponding one of the multiplexed signal lines 19 of the same electrode sheet 10 for transmitting an alternating current signal and transmitting a temperature detection signal. Specifically, the first bidirectional switching switch 26-1 is used to control the switching of the first multiplexed signal line 19-1 of the corresponding electrode sheet 10 between transmitting an alternating current signal and transmitting a temperature detection signal, thereby controlling the conduction of the dielectric elements 15 of the electrode units 12-1, electrode units 12-6, electrode units 12-11, and electrode units 12-16 in the first column group of the electrode sheet 10 and the conduction of the signal terminals 14-2 of the temperature sensors 14 of the electrode units 12-1, electrode units 12-6, electrode units 12-11, and electrode units 12-16 in the first column group, and cooperating with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4, so that the first column of electrode units 12-1, electrode units 12-6, electrode units 12-11, and electrode units 12-16 transmit an alternating current signal to the patient or output the temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23; the second bidirectional switching switch 26-2 is used to control the switching of the second multiplexed signal line 19-2 of the corresponding electrode sheet 10 between transmitting an alternating current signal and transmitting a temperature detection signal, thereby controlling the conduction of the dielectric elements 15 of the electrode units 12-2, electrode units 12-7, electrode units 12-12, and electrode units 12-17 in the second column group of the electrode sheet 10 and the conduction of the signal terminals 14-2 of the temperature sensors 14 of the electrode units 12-2, electrode units 12-7, electrode units 12-12, and electrode units 12-17 in the second column group, and cooperating with the corresponding grounding switch 25-1, grounding switch 25-2, grounding switch 25-3, and grounding switch 25-4, so that the second column of electrode units 12-2, electrode units 12-7, electrode units 12-12, and electrode units 12-17 transmit an alternating current signal to the patient or output the temperature detection signals collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23;The third bidirectional switch 26-3 is used to control the switching of the third dual-purpose signal line 19-3 of the corresponding electrode plate 10 between transmitting an alternating current signal and transmitting a temperature detection signal, thereby controlling the conduction of each dielectric element 15 of the electrode units 12-3, 12-8, 12-13, and 12-18 in the third column group of the electrode plate 10 and the conduction of the signal terminals 14-2 of each temperature sensor 14 of the electrode units 12-3, 12-8, 12-13, and 12-18 in the third column group. The switch cooperates with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4 to enable the third column electrode units 12-3, 12-8, 12-13, and 12-18 to transmit an alternating current signal to the patient or output the temperature detection signal collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23. The fourth bidirectional switch 26-4 is used to control the switching of the fourth dual-purpose signal line 19-4 of the corresponding electrode plate 10 between transmitting an alternating current signal and transmitting a temperature detection signal, thereby controlling the conduction of each dielectric element 15 of the electrode units 12-4, 12-9, 12-14, and 12-19 in the fourth column group of the electrode plate 10 and the conduction of the signal terminals 14-2 of each temperature sensor 14 of the electrode units 12-4, 12-9, 12-14, and 12-19 in the fourth column group. The switch cooperates with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4 to enable the fourth column electrode units 12-4, 12-9, 12-14, and 12-19 to transmit an alternating current signal to the patient or output the temperature detection signal collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23;The fifth bidirectional switch 26-5 is used to control the switching of the fifth dual-purpose signal line 19-5 of the corresponding electrode plate 10 between transmitting an alternating current signal and transmitting a temperature detection signal, thereby controlling the conduction of each dielectric element 15 of the electrode units 12-5, 12-10, 12-15, and 12-20 in the fifth column group of the electrode plate 10 and the conduction of the signal terminals 14-2 of each temperature sensor 14 of the electrode units 12-5, 12-10, 12-15, and 12-20 in the fifth column group. It cooperates with the corresponding first grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4 to enable the fifth column electrode units 12-5, 12-10, 12-15, and 12-20 to transmit an alternating current signal to the patient or output the temperature detection signal collected by the temperature sensors 14 of these electrode units 12 to the corresponding analog-to-digital converter 23. When the input end 2 of each group of bidirectional switches 26 is turned on and the acquisition end 1 is turned off, an alternating current signal can be transmitted to the dielectric elements 15 of each electrode unit 12 of the corresponding electrode plate 10. When the acquisition end 1 of each group of bidirectional switches 26 is turned on and the input end 2 is turned off, it can cooperate with each grounding switch 25 in the corresponding group of grounding switches 25 to transmit the temperature detection signal collected by the temperature sensors 14 of each electrode unit 12 on the electrode plate 10 in a time-sharing manner. The above-mentioned bidirectional switch 26 can be a mechanical switch, such as a relay. The bidirectional switch 26 can also be an electronic switch. The switching of the acquisition end 1 and the input end 2 of each bidirectional switch 26 can be controlled by the first controller 22 of the adapter 20.;

[0091] In this embodiment, multiple groups of bidirectional switches 26 are all electronic switches. The first controller 22 is communicatively connected to multiple groups of bidirectional switches 26 and is used to control multiple bidirectional switches 26 in each group of bidirectional switches 26 to switch between their respective acquisition ends 1 and input ends 2, and cooperate with the closing or opening of the corresponding grounding switch 25 to continuously monitor the temperature of the patient's body surface detected by all the temperature sensors 14 on the electrode plate 10 or transmit an alternating current signal to the patient.

[0092] In this embodiment, each group of analog-to-digital converters 23 is electrically connected to the acquisition ends 1 of a plurality of bidirectional switches 26 in the corresponding group of bidirectional switching switches 26 through a plurality of circuit lines (not labeled) in the adapter 20, and is configured to receive the temperature detection signals transmitted by the multi-purpose signal lines 19 of the corresponding electrode plates 10, and convert the temperature detection signals from analog signals into digital signals. Each group of analog-to-digital converters 23 includes a plurality of detection channels A, B, C, D, and E. Each detection channel A, B, C, D, and E is used to connect to a corresponding one of the multi-purpose signal lines 19 through the corresponding bidirectional switch 26. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of bidirectional switches 26 in the corresponding group. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of column groups of the electrode units 12 of the corresponding electrode plate 10. Specifically, the number of detection channels in each group of analog-to-digital converters 23 is equal to the number of bidirectional switches 26 in a corresponding group of bidirectional switching switches 26, and is not less than the number of column groups of the electrode units 12 of the corresponding electrode plate 10. As Figure 3 shown, each group of analog-to-digital converters 23 includes a total of 5 detection channels A, B, C, D, and E, namely the first detection channel A, the second detection channel B, the third detection channel C, the fourth detection channel D, and the fifth detection channel E. The first detection channel A is connected to the first multi-purpose signal line 19-1 through the acquisition end 1 of the first bidirectional switch 26-1, the second detection channel B is connected to the second multi-purpose signal line 19-2 through the acquisition end 1 of the second bidirectional switch 26-2, the third detection channel C is connected to the third multi-purpose signal line 19-3 through the acquisition end 1 of the third bidirectional switch 26-3, the fourth detection channel D is connected to the fourth multi-purpose signal line 19-4 through the acquisition end 1 of the fourth bidirectional switch 26-4, and the fifth detection channel E is connected to the fifth multi-purpose signal line 19-5 through the acquisition end 1 of the fifth bidirectional switch 26-5. Each detection channel A, B, C, D, and E is used to receive the temperature detection signals collected by the temperature sensors 14 of the electrode units 12 connected to the corresponding multi-purpose signal lines 19. In addition, each of the detection channels A, B, C, D, and E is connected to a first power supply module 29 for providing a detection voltage to this detection channel A, B, C, D, and E through a corresponding voltage-dividing resistor 24 in the adapter 20, and the first power supply module 29 provides a DC signal.

[0093] In this embodiment, the first communication unit 27 is configured to acquire digital signals output by multiple groups of analog-to-digital converters 23 and send the digital signals to the electric field generator 30. The electric field generator 30 is further configured to control and adjust the voltage or current or power of the alternating current signal provided to the multiple electrode units 12 of the electrode patch 10 according to the received digital signals. Exemplarily, when any one of the multiple received digital signals exceeds a preset threshold, it indicates that the temperature at the human body surface where the dielectric element 15 corresponding to at least one temperature sensor 14 in the electrode patch 10 is attached exceeds the preset threshold temperature (such as 41°C, 42°C, etc.). At this time, the voltage or current or power of the alternating current signal output by the electric field generator 30 can be appropriately reduced to avoid the temperature of the electrode units 12 of the electrode patch 10 being too high when applying the alternating current signal, causing low-temperature burns to the patient's skin. The above preset threshold temperature and preset threshold can be determined according to the human safety threshold. The first communication unit 27 is controlled by the first controller 22 and serially transmits the digital signals converted by the multiple groups of analog-to-digital converters 23. In this embodiment, the preset temperature threshold can be a value within 36°C - 45°C.

[0094] Reference Figure 4 and Figure 5 , in this embodiment, the first power module 29 is electrically connected to the second power module 31 of the electric field generator 30 correspondingly and is configured to supply power to the first controller 22, multiple groups of analog-to-digital converters 23, and the first communication unit 27 of the adapter 20. A first connector 40 is connected between each electrode patch 10 and the adapter 20. The first connector 40 is adapted to connect the corresponding electrode patch 10 to the adapter 20. Combining Figure 1 as shown, the first connector 40 includes a first plug 41 provided at one end of the first cable 13 away from the electrode patch 10 and a first socket 42 provided on the adapter 20. The first plug 41 and the first socket 42 are push-button spring connectors, that is, the first connector 40 connects the adapter 20 and the electrode patch 10 in the form of a connector. Each first cable 13 has 5 wires electrically connected to the bidirectional switches 26-1, 26-2, 26-3, 26-4, 26-5 in the corresponding group of bidirectional switches 26 one by one and 4 wires electrically connected to the grounding switches 25-1, 25-2, 25-3, 25-4 in the corresponding group of grounding switches 25 one by one. That is, each first connector 40 is electrically connected to a corresponding group of bidirectional switches 26 and a corresponding group of grounding switches 25 of the adapter 20 through 9 wires; and is connected to the electric field generator 30 through a corresponding AC signal line 28 of the adapter 20.

[0095] A second connector 50 is provided between the adapter 20 and the electric field generator 30. The second connector 50 is adapted to connect the electric field generator 30 to the adapter 20. The adapter 20 further includes a second cable 21 connected to the second connector 50. The second connector 50 includes a second plug 51 provided at one end of the second cable 21 away from the first controller 22 and a second socket 52 provided on the electric field generator 30. The second plug 51 and the second socket 52 are push-type spring connectors, that is, the second connector 50 connects the adapter 20 and the electric field generator 30 in the form of a connector. Each first connector 40, such as X1, Y1, X2, Y2, is connected to the second connector 50 through a corresponding AC signal line 28. Each first connector 40, such as X1, Y1, X2, Y2, is connected to a corresponding group of grounding switches 25 and a corresponding group of analog-to-digital converters 23. Specifically, each first connector 40 is connected to the second connector 50 and a corresponding group of analog-to-digital converters 23 through a corresponding group of bidirectional switching switches 26. Taking 4 electrode plates 10 as an example, the second cable 21 has 8 wires, including 4 wires respectively electrically connected to the corresponding AC signal lines 28 one by one and used to transmit AC signal wires 1 to 4, 1 wire electrically connected to the data receiving line RX of the first communication unit 27, 1 wire electrically connected to the data sending line TX of the first communication unit 27, 1 wire electrically connected to the VCC power supply line of the first power module 29, and 1 wire electrically connected to the GND line of the first power module 29. The second connector 50 is connected to the first communication unit 27 through the data receiving line RX and the data sending line TX. The VCC pin of the second connector 50 is connected to the VVC power supply line of the first power module 29. The GND pin of the second connector 50 is connected to the GND line of the first power module 29 and grounded. The VCC pin of the second connector 50 is also connected to the corresponding group of voltage dividing resistors 24 and the corresponding group of analog-to-digital converters 23 through the VCC power supply line of the first power module 29.

[0096] Reference Figure 5, the electric field generator 30 includes: a second power supply module 31, a second controller 32, an AC signal generator 34, a second communication unit 33, and a set of AC signal switches 35. The VCC pin of the second connector 50 is also electrically connected to the VCC power line of the second power supply module 31, and the GND pin of the second connector 50 is grounded through the GND line of the second power supply module 31. The second power supply module 31 is also respectively connected to and supplies power to the second controller 32 and the AC signal generator 34. The second communication unit 33 is electrically connected to the wire 5 of the second connector 50 through its data receiving line RX and electrically connected to the wire 6 of the second connector 50 through its data sending line TX, so as to realize information interaction between the electric field generator 30 and the adapter 20. The second controller 32 is also electrically connected to the second communication unit 33, the AC signal generator 34, and a set of AC signal switches 35 at the same time. The second controller 32 is configured to control the opening and closing of each AC signal switch 35 in the set of AC signal switches 35 and adjust the relevant parameters of the alternating current signal applied by the AC signal generator 34 according to the relevant digital signals received from the adapter 20 by the second communication unit 33. The AC signal generator 34 is electrically connected to the wires 1 to 4 for transmitting the alternating current signal of the second connector 50 through a set of AC signal switches 35. The set of AC signal switches 35 includes a plurality of AC signal switches 35, and the plurality of AC signal switches 35 are arranged in one-to-one correspondence with the plurality of electrode plates 10. Each AC signal switch 35 is electrically connected to one of the wires 1, 2, 3, 4 for transmitting the alternating current signal in the second connector 50 through an AC signal wiring 36 and is electrically connected to the corresponding electrode plate 10 through the corresponding wires 1, 2, 3, 4 of the second connector 50 to deliver the alternating current signal to each electrode plate 10. The AC signal generator 34 is electrically connected to the set of AC signal switches 35 through a set of AC signal wirings 36.

[0097] Specifically, the number of AC signal switches 35 of the electric field generator 30 is related to the number of electrode plates 10. In this embodiment, the number of AC signal switches 35 is equal to the number of electrode plates 10 and both are 4. The AC signal switch 35 includes a first AC signal switch 35-1, a second AC signal switch 35-2, a third AC signal switch 35-3, and a fourth AC signal switch 35-4 that are respectively and electrically connected to wires 1 to 4 of the second connector 50 through corresponding AC signal wiring 36 one by one.One end of the first AC signal switch 35-1 is electrically connected to the AC signal generator 34 through the first AC signal connection line 36-1 of the electric field generator 30, and the other end is electrically connected to the corresponding wire 1 for transmitting an alternating current signal in the second connector 50 through the first AC signal connection line 36-1 and is electrically connected to the AC signal line 28 at the port X1 of the adapter 20 through the wire 1 of the second connector 50. The AC signal line 28 at the port X1 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at the port X1 of the adapter 20 is electrically connected to the corresponding electrode plate 10 to control whether the AC signal generator 34 delivers an alternating current signal to the electrode plate 10 electrically connected to the port X1 of the adapter 20. One end of the second AC signal switch 35-2 is electrically connected to the AC signal generator 34 through the second AC signal connection line 36-2 of the electric field generator 30, and the other end is electrically connected to the corresponding wire 2 for transmitting an alternating current signal in the second connector 50 through the second AC signal connection line 36-2 and is electrically connected to the AC signal line 28 at the port Y1 of the adapter 20 through the wire 2 of the second connector 50. The AC signal line 28 at the port Y1 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at the port Y1 of the adapter 20 is electrically connected to the corresponding electrode plate 10 to control whether the AC signal generator 34 delivers an alternating current signal to the electrode plate 10 electrically connected to the port Y1 of the adapter 20. One end of the third AC signal switch 35-3 is electrically connected to the AC signal generator 34 through the third AC signal connection line 36-3 of the electric field generator 30, and the other end is electrically connected to the corresponding wire 3 for transmitting an alternating current signal in the second connector 50 through the third AC signal connection line 36-3 and is electrically connected to the AC signal line 28 at the port X2 of the adapter 20 through the wire 3 of the second connector 50. The AC signal line 28 at the port X2 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at the port X2 of the adapter 20 is electrically connected to the corresponding electrode plate 10 to control whether the AC signal generator 34 delivers an alternating current signal to the electrode plate 10 electrically connected to the port X2 of the adapter 20. One end of the fourth AC signal switch 35-4 is electrically connected to the AC signal generator 34 through the fourth AC signal connection line 36-4 of the electric field generator 30, and the other end is electrically connected to the corresponding wire 4 for transmitting an alternating current signal in the second connector 50 through the fourth AC signal connection line 36-4 and is electrically connected to the AC signal line 28 at the port Y2 of the adapter 20 through the wire 4 of the second connector 50. The AC signal line 28 at the port Y2 of the adapter 20 is electrically connected to the first connector 40, and the first connector 40 at the port Y2 of the adapter 20 is electrically connected to the corresponding electrode plate 10 to control whether the AC signal generator 34 delivers an alternating current signal to the electrode plate 10 electrically connected to the port Y1 of the adapter 20.

[0098] The following will refer toFigures 3 to 5 The working principle of the tumor electrotherapy system 100 of this embodiment will be introduced in detail.

[0099] Specifically, when it is necessary to detect the temperatures of the electrode units 12 of a certain electrode sheet 10, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls each acquisition terminal 1 of each bidirectional switch 26 in a group of bidirectional switches 26 electrically connected to the electrode sheet 10 to conduct, and the input terminal 2 to disconnect, so as to disconnect the alternating current signal applied to the electrode sheet 10; at the same time, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls each grounding switch 25 in a group of grounding switches 25 electrically connected to the electrode sheet 10 to conduct in sequence at different times. At this time, the temperature detection signals collected by the temperature sensors 14 of each electrode unit 12 in each row group of the electrode sheet 10 can be collected in sequence at different times through the multiple detection channels A, B, C, D, and E of a group of analog-to-digital converters 23 corresponding to the electrode sheet 10. Each detection channel A, B, C, D, and E of each group of analog-to-digital converters 23 only collects the temperature detection signals of the temperature sensors 14 of the corresponding electrode units 12 in the same row group of the electrode sheet 10 at the same time. The above temperature detection signals can be characterized by voltage values. Only 1 of the 4 grounding switches 25 in a group of grounding switches 25 corresponding to the electrode sheet 10 can conduct at the same moment, and the other 3 are disconnected. All 5 bidirectional switches 26 in a group of bidirectional switches 26 corresponding to the group of analog-to-digital converters 23 are switched to their respective acquisition terminals 1 so that the various two-way signal lines 19 of the electrode sheet 10 are electrically connected to the corresponding detection channels A, B, C, D, and E of the corresponding group of analog-to-digital converters 23 in a one-to-one correspondence and conduct. With such a setting, the group of analog-to-digital converters 23 can collect the voltage values of the temperature sensors 14 of the electrode units 12 in the same row group short-circuited by a ground wire 18 corresponding to the conducting grounding switch 25.

[0100] Specifically, when the first earthing switch 25-1 is closed, the second earthing switch 25-2, the third earthing switch 25-3 and the fourth earthing switch 25-4 are all open, and the first two-way switching switch 26-1, the second two-way switching switch 26-2, the third two-way switching switch 26-3, the fourth two-way switching switch 26-4 and the fifth two-way switching switch 26-5 are all switched to their respective acquisition ends 1, the temperature sensors 14 of the electrode units 12-1 to 12-5 in the first row group are powered on, and the temperature sensors 14 of the electrode units 12-6 to 12-20 in the remaining row groups are powered off. The signal terminals 14-2 of the temperature sensors 14 of the electrode units 12-1, 12-6, 12-11, and 12-16 are short-circuited by the first detection channel A in this group of analog-to-digital converters 23. Since only the grounding terminal 14-1 of the temperature sensor 14 of the electrode unit 12-1 is conductively grounded, while the grounding terminals 14-1 of the temperature sensors 14 of the electrode units 12-6, 12-11, and 12-16 are all open, and a diode 16 is provided in series with the temperature sensor 14 on each electrode unit 12, the remaining temperature sensors 14 in the first row do not affect the resistance value of the temperature sensor 14 of the electrode unit 12-1. Therefore, only the temperature sensor 14 of the electrode unit 12-1 operates effectively on the first detection channel A of this group of analog-to-digital converters 23, and the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of the electrode unit 12-1. Similarly, the voltage value collected by the second detection channel B in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-2. The voltage value collected by the third detection channel C in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-3. The voltage value collected by the fourth detection channel D in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-4. The voltage value collected by the fifth detection channel E in this analog-to-digital converter 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-5.

[0101] When the second earthing switch 25-2 is closed, the first earthing switch 25-1, the third earthing switch 25-3 and the fourth earthing switch 25-4 are all open, and the first double-way changeover switch 26-1, the second double-way changeover switch 26-2, the third double-way changeover switch 26-3, the fourth double-way changeover switch 26-4 and the fifth double-way changeover switch 26-5 are all switched to their respective acquisition ends 1, the temperature sensors 14 of the electrode units 12-6 to 12-10 in the second row group are powered on, and the temperature sensors 14 of the electrode units 12-1 to 12-5 and the electrode units 12-11 to 12-20 in the remaining row groups are powered off. The signal ends 14-2 of the temperature sensors 14 of the electrode units 12-1, 12-6, 12-11 and 12-16 are short-circuited by the first detection channel A in this group of analog-to-digital converters 23. Since only the grounding end 14-1 of the temperature sensor 14 of the electrode unit 12-6 is conductively grounded, while the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12-1, 12-11 and 12-16 are all open, and a diode 16 is provided in series with the temperature sensor 14 on each electrode unit 12, the remaining temperature sensors 14 in the second row will not affect the resistance value of the temperature sensor 14 of the electrode unit 12-6. Therefore, only the temperature sensor 14 of the electrode unit 12-6 operates effectively on the first detection channel A of this group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of the electrode unit 12-6. Similarly, the voltage value collected by the second detection channel B in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-7. The voltage value collected by the third detection channel C in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-8. The voltage value collected by the fourth detection channel D in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-9. The voltage value collected by the fifth detection channel E in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-10.

[0102] When the third grounding switch 25-3 is closed, the first grounding switch 25-1, the second grounding switch 25-2 and the fourth grounding switch 25-4 are all open, and the first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4 and the fifth bidirectional switch 26-5 are all switched to their respective acquisition ends 1, the temperature sensors 14 of the electrode units 12-11 to 12-15 in the third row group are powered on, and the temperature sensors 14 of the electrode units 12-1 to 12-10 and the electrode units 12-16 to 12-20 in the remaining row groups are powered off. The signal terminals 14-2 of the temperature sensors 14 of the electrode units 12-1, 12-6, 12-11 and 12-16 are short-circuited by the first detection channel A in this group of analog-to-digital converters 23. Since only the grounding terminal 14-1 of the temperature sensor 14 of the electrode unit 12-11 is conductively grounded, and the grounding terminals 14-1 of the temperature sensors 14 of the electrode units 12-1, 12-6 and 12-16 are all open, and a diode 16 in series with the temperature sensor 14 is provided on each electrode unit 12, the remaining temperature sensors 14 in the third row will not affect the resistance value of the temperature sensor 14 of the electrode unit 12-11. Therefore, only the temperature sensor 14 of the electrode unit 12-11 operates effectively on the first detection channel A of this group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of the electrode unit 12-11. Similarly, the voltage value collected by the second detection channel B in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-12. The voltage value collected by the third detection channel C in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-13. The voltage value collected by the fourth detection channel D in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-14. The voltage value collected by the fifth detection channel E in this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-15.

[0103] When the fourth grounding switch 25-4 is closed, the first grounding switch 25-1, the second grounding switch 25-2 and the third grounding switch 25-3 are all open, and the first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4 and the fifth bidirectional switch 26-5 are all switched to their respective acquisition ends 1, the temperature sensors 14 of the electrode units 12-16 to 12-20 of the fourth row group are powered on, and the temperature sensors 14 of the electrode units 12-1 to 12-15 of the remaining row groups are powered off. In the first detection channel A of this group of analog-to-digital converters 23, the signal terminals 14-2 of the temperature sensors 14 of the electrode unit 12-1, the electrode unit 12-6, the electrode unit 12-11, and the electrode unit 12-16 are short-circuited. Since only the grounding terminal 14-1 of the temperature sensor 14 of the electrode unit 12-16 is conductively grounded, and the grounding terminals 14-1 of the temperature sensors 14 of the electrode unit 12-1, the electrode unit 12-6, and the electrode unit 12-11 are all open, and a diode 16 is provided in series with the temperature sensor 14 on each electrode unit 12, the remaining temperature sensors 14 in the fourth row do not affect the resistance value of the temperature sensor 14 of the electrode unit 12-16. Therefore, only the temperature sensor 14 of the electrode unit 12-16 operates effectively on the first detection channel A of this group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of the electrode unit 12-16. Similarly, the voltage value collected on the second detection channel B of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-17. The voltage value collected on the third detection channel C of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-18. The voltage value collected on the fourth detection channel D of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-19. The voltage value collected on the fifth detection channel E of this group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-20. Thus, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 can collect the temperature detection signals of the temperature sensors 14 of all the electrode units 12 of a certain electrode plate 10 by controlling a group of bidirectional switches 26 and a group of grounding switches 25 that are all electrically connected to the electrode plate 10. Similarly, the temperature detection signals of the temperature sensors 14 of the electrode units 12 of other electrode plates 10 can be obtained.

[0104] The first controller 22, multiple groups of analog-to-digital converters 23, and multiple groups of bidirectional switches 26 can automatically perform operations through pre-programmed program codes. For example, the first controller 22 first controls all the bidirectional switches 26 in the corresponding group of bidirectional switches 26 to switch to the acquisition end 1, so that the acquisition ends 1 of these bidirectional switches 26 are all turned on and the input ends 2 are all turned off, so that the respective dual-purpose signal lines 19 of the corresponding electrode plates 10 are electrically connected to the corresponding group of analog-to-digital converters 23. Then, the first grounding switch 25-1 in the corresponding group of grounding switches 25 is closed, and the remaining second grounding switch 25-2, third grounding switch 25-3, and fourth grounding switch 25-4 in this group of grounding switches 25 are opened. During this period, each detection channel A, B, C, D, E of the group of analog-to-digital converters 23 obtains the temperature detection signals of the respective temperature sensors 14 of the electrode units 12 located in the first row group in the corresponding electrode plate 10, converts them into digital signals, and stores them in a separately provided memory. Then, after a preset time interval, the first controller 22 closes the second grounding switch 25-2 in this group of grounding switches 25, and opens the first grounding switch 25-1, third grounding switch 25-3, and fourth grounding switch 25-4 in this group of grounding switches 25. During this period, each detection channel A, B, C, D, E of the group of analog-to-digital converters 23 obtains the temperature detection signals of the respective temperature sensors 14 of the electrode units 12 located in the second row group. By sequentially and separately turning on each grounding switch 25 in this group of grounding switches 25 in this way, the temperature detection signals of all the temperature sensors 14 in each row group of the electrode plate 10 can be obtained. Similarly, the temperature detection signals of all the temperature sensors 14 on at least a pair of electrode plates 10 are obtained through this kind of operation.

[0105] The tumor electro-field therapy system 100 of the present application can achieve real-time and comprehensive monitoring of the temperatures of all electrode units 12 on the electrode patch 10 without increasing the weight of the electrode patch 10 and without increasing the cores of the first cables 13 electrically connected to the electrode patch 10. Furthermore, it can judge whether the electrode patch 10 is qualified based on the obtained temperature detection signals; or it can judge whether there are faults or abnormalities in the temperature sensors 14 of the electrode patch 10 based on the obtained temperature detection signals, and judge whether it is necessary to replace the electrode patch 10 based on the number of temperature sensors 14 with faults or abnormalities; or it can identify the type of the electrode patch based on the obtained temperature detection signals when the electrode patch is qualified; or it can judge whether there is an over-temperature situation in the electrode units 12 of the electrode patch 10 based on the obtained temperature detection signals when the electrode patch is qualified, and then control the alternating electric signals applied to the electrode patch 10 or the corresponding column electrode units 12 of the electrode patch 10 to avoid low-temperature burns on the patient's body surface during tumor treatment through the electrode patch 10. In addition, the flexible circuit board 11 of the electrode patch 10 of the present application electrically connects the dielectric element 15 of the same electrode unit 12 and the signal terminal 14-2 of the temperature sensor 14 through the same dual-purpose signal line 19 arranged thereon. While it can transmit both alternating current signals and direct current signals for temperature signal acquisition and the acquired temperature detection signals through the dual-purpose signal line 19, it also greatly reduces the number of conductive traces (ground wire 18, dual-purpose signal line 19) arranged thereon, reduces the wiring difficulty of the flexible circuit board 11, simplifies the manufacturing process, also reduces the weight of the flexible circuit board 11, and reduces the manufacturing cost. The electrode patch 10 of the present application can also be switched between applying alternating current signals for tumor treatment and transmitting direct current signals for temperature acquisition and transmitting the acquired temperature detection signals through the combined control of a ground switch 25 electrically connected to the ground wire 18 arranged thereon and a bidirectional switch 26 electrically connected to the dual-purpose signal line 19.

[0106] When an alternating current signal needs to be applied to a patient through each electrode unit 12 of a certain electrode patch 10, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls all the grounding switches 25 in a group of grounding switches 25 corresponding to the electrode patch 10 to be disconnected, and at the same time controls all the bidirectional switching switches 26 in a group of bidirectional switching switches 26 corresponding to the electrode patch 10 to be switched to their respective input terminals 2, so that the acquisition terminals 1 of these bidirectional switching switches 26 are all disconnected and the input terminals 2 are all conducted, realizing that each two-way signal line 19 of the electrode patch 10 is electrically connected to an AC signal line 28 corresponding to the adapter 20 and the electrode patch 10, thereby transmitting the alternating current signal to each electrode unit 12 of the electrode patch 10.When the temperature detection signals of the temperature sensors 14 of all the electrode units 12 of the detected electrode patch 10 are much lower than the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 34 through its second controller 32 to continue generating an alternating current signal with an increasing voltage or current amplitude or a constant voltage or current amplitude, and then transmits it to the corresponding pair of electrode patches 10 through a corresponding AC signal line 28 of the adapter 20, so as to continue applying the alternating current signal to the pair of electrode patches 10; when the temperature detection signals of the temperature sensors 14 of all the electrode units 12 of the detected electrode patch 10 are lower than but close to the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 can reduce the voltage or current of the alternating current signal generated by the AC signal generator 34 through the second controller 32, and then reduce the voltage or current of the alternating current signal applied to the pair of electrode patches 10; when the temperature detection signal of the temperature sensor 14 of an electrode unit 12 of a certain electrode patch 10 is detected to be greater than the preset temperature threshold, the electric field generator 30 controls the AC signal switch 35 electrically connected to the electrode patch 10 to be turned off through the second controller 32 to stop applying the alternating current signal to the electrode patch 10; or the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls all the bidirectional switches 26 in a group of bidirectional switches 26 electrically connected to the electrode patch 10 to switch from their input terminals 2 to the acquisition terminals 1, that is, controls all the acquisition terminals 1 of all the bidirectional switches 26 in a group of bidirectional switches 26 electrically connected to the electrode patch 10 to be turned on and all the input terminals 2 to be turned off, so as to stop applying the alternating current signal to the electrode patch 10; or, when the temperature detection signal of the temperature sensor 14 of an electrode unit 12 of a certain electrode patch 10 is detected to be greater than the preset temperature threshold, the second controller 32 of the electric field generator 30 controls the AC signal switch 35 electrically connected to the electrode patch 10 to continue to be turned on, and the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls a bidirectional switch 26 electrically connected to the electrode unit 12 of the electrode patch 10 to switch from its input terminal 2 to its acquisition terminal 1, and at the same time, the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls the remaining bidirectional switches 26 electrically connected to the electrode units 12 whose temperature detection signals do not exceed the preset temperature threshold and are in different columns from the electrode units 12 whose temperature detection signals exceed the preset temperature threshold of the electrode patch 10 to keep their input terminals 2 electrically connected respectively, so as to stop applying the alternating current signal to all the electrode units 12 in the column where the electrode unit 12 with the temperature detection signal exceeding the preset temperature threshold of the electrode patch 10 is located, and continue to apply the alternating current signal to the remaining column electrode units 12 of the electrode patch 10 whose temperature detection signals do not exceed the preset temperature threshold. Thus, a control method for the regional application of the alternating current signal of the tumor electric field treatment system 100 based on the temperature detection signal is realized.When applying an alternating current signal, all the grounding switches 25 are opened.

[0107] In the embodiment of the present application, the grounding switches 25 respectively and electrically connected to the multiple ground wires 18 of the electrode sheet 10 one by one, and the bidirectional switching switches 26 respectively and electrically connected to the multiple dual-purpose signal lines 19 of the electrode sheet 10 one by one are all arranged in the adapter 20. However, in other embodiments, the grounding switches 25 electrically connected to the ground wires 18 and the bidirectional switching switches 26 electrically connected to the dual-purpose signal lines 19 can also be arranged on the electrode sheet 10 or in the electric field generator 30, which will not be elaborated here. In addition, the analog-to-digital converter 23 arranged in the adapter 20 can also be arranged in the electric field generator 30 and directly controlled by the second controller 32.

[0108] The present application also provides other embodiments of the electrode sheet 10. The differences among the multiple embodiments are mainly the differences in the number of the electrode units 12 and / or the different electrical connection arrangement modes of the electrode units 12, which will be described separately below.

[0109] Reference Figure 6As shown, the electrode sheet 10A of the second embodiment is provided with 19 electrode units 12. The flexible printed circuit board 11A electrically connects and arranges these 19 electrode units 12 in four rows and five columns, where three rows each have 5 electrode units 12, and the remaining row has 4 electrode units 12. The electrode sheet 10A includes 4 ground wires 18 and 5 dual-purpose signal lines 19. Each ground wire 18 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12 in the same row group. Each dual-purpose signal line 19 shorts the dielectric elements 15 of the electrode units 12 in each column group and the signal terminals 14-2 of the temperature sensors 14 respectively, and is used to receive temperature detection signals or transmit alternating current signals. The 4 ground wires 18 of the electrode sheet 10A include a first ground wire 18-1, a second ground wire 18-2, a third ground wire 18-3, and a fourth ground wire 18-4. The first row group includes electrode units 12-1 to electrode units 12-5, the second row group includes electrode units 12-6 to electrode units 12-10, the third row group includes electrode units 12-11 to electrode units 12-15, and the fourth row group includes electrode units 12-16 to electrode units 12-19. Specifically, the first ground wire 18-1 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the five electrode units 12 from electrode unit 12-1 to electrode unit 12-5 in the first row group; the second ground wire 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the five electrode units 12 from electrode unit 12-6 to electrode unit 12-10 in the second row group, the third ground wire 18-3 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the five electrode units 12 from electrode unit 12-11 to electrode unit 12-15 in the third row group, and the fourth ground wire 18-4 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the four electrode units 12 from electrode unit 12-16 to electrode unit 12-19 in the fourth row group. In short, each ground wire 18 shorts and grounds the ground terminals 14-1 of the temperature sensors 14 of all the electrode units 12 in each row group.

[0110] The five-way dual-purpose signal line 19 of the electrode sheet 10A includes a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is respectively and simultaneously connected to the signal terminals 14-2 of the dielectric elements 15 and the respective temperature sensors 14 of four electrode units 12, namely the electrode unit 12-1, the electrode unit 12-6, the electrode unit 12-11, and the electrode unit 12-16; One end of the second dual-purpose signal line 19-2 is respectively and simultaneously connected to the signal terminals 14-2 of the dielectric elements 15 and the respective temperature sensors 14 of four electrode units 12, namely the electrode unit 12-2, the electrode unit 12-7, the electrode unit 12-12, and the electrode unit 12-17; One end of the third dual-purpose signal line 19-3 is respectively and simultaneously connected to the signal terminals 14-2 of the dielectric elements 15 and the respective temperature sensors 14 of four electrode units 12, namely the electrode unit 12-3, the electrode unit 12-8, the electrode unit 12-13, and the electrode unit 12-18; One end of the fourth dual-purpose signal line 19-4 is respectively and simultaneously connected to the signal terminals 14-2 of the dielectric elements 15 and the respective temperature sensors 14 of four electrode units 12, namely the electrode unit 12-4, the electrode unit 12-9, the electrode unit 12-14, and the electrode unit 12-19; One end of the fifth dual-purpose signal line 19-5 is respectively and simultaneously connected to the signal terminals 14-2 of the dielectric elements 15 and the temperature sensor 14 of three electrode units 12, namely the electrode unit 12-5, the electrode unit 12-10, and the electrode unit 12-15. In short, each dual-purpose signal line 19 short-circuits in parallel the dielectric elements 15 and the signal terminals 14-2 of the respective temperature sensors 14 of the electrode units 12 located in the same column group and is used to connect to the adapter 20.

[0111] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 of the adapter 20 are respectively and electrically connected in one-to-one correspondence with the first ground wire 18-1, the second ground wire 18-2, the third ground wire 18-3, and the fourth ground wire 18-4 of the electrode plate 10A through the first connector 40A. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 on the adapter 20 are respectively and electrically connected in one-to-one correspondence with the first dual-purpose signal wire 19-1, the second dual-purpose signal wire 19-2, the third dual-purpose signal wire 19-3, the fourth dual-purpose signal wire 19-4, and the fifth dual-purpose signal wire 19-5 of the electrode plate 10A through the first connector 40A. The working mode of the tumor electric field treatment system formed by the electrode plate 10A, the adapter 20, and the electric field generator 30 is the same as that of the aforementioned tumor electric field treatment system 100. When all the grounding switches 25 are all disconnected and the input ends 2 of all the bidirectional switching switches 26 are conducting and the acquisition ends 1 are disconnected, all the dual-purpose signal wires 19 are conducting with the AC signal wire 28, and all the electrode units 12 are connected to the AC signal; when the acquisition ends 1 of all the bidirectional switching switches 26 are conducting and the input ends 2 are disconnected, by sequentially conducting each grounding switch 25, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained in sequence.

[0112] Reference Figure 7As shown, the electrode sheet 10B of the third embodiment is provided with 17 electrode units 12. The flexible circuit board 11B electrically connects and arranges these 17 electrode units 12 in four rows and five columns, where three rows each have 5 electrode units 12, and the remaining row has 2 electrode units 12. The electrode sheet 10B includes 4 ground wires 18 and 5 dual-purpose signal lines 19. Each ground wire 18 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12 in the same row group. Each dual-purpose signal line 19 shorts the dielectric elements 15 of the electrode units 12 in each column group and the signal terminals 14-2 of the temperature sensors 14 respectively, and is used to receive temperature detection signals or transmit alternating current signals. The 4 ground wires 18 of the electrode sheet 10B include a first ground wire 18-1, a second ground wire 18-2, a third ground wire 18-3, and a fourth ground wire 18-4. The first row group includes electrode units 12-1 to electrode units 12-5, the second row group includes electrode units 12-6 to electrode units 12-10, the third row group includes electrode units 12-11 to electrode units 12-15, and the fourth row group includes electrode units 12-16 and electrode units 12-17. Specifically, the first ground wire 18-1 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the five electrode units 12 from electrode unit 12-1 to electrode unit 12-5 in the first row group; the second ground wire 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the five electrode units 12 from electrode unit 12-6 to electrode unit 12-10 in the second row group, the third ground wire 18-3 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the five electrode units 12 from electrode unit 12-11 to electrode unit 12-15 in the third row group, and the fourth ground wire 18-4 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the two electrode units 12 from electrode unit 12-16 to electrode unit 12-17 in the fourth row group. In short, each ground wire 18 shorts and grounds the ground terminals 14-1 of the temperature sensors 14 of all the electrode units 12 in the corresponding row group.

[0113] The five-way dual-purpose signal line 19 of the electrode sheet 10B includes a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is respectively and simultaneously connected to the dielectric elements 15 of the four electrode units 12 of the electrode unit 12-1, the electrode unit 12-6, the electrode unit 12-11, and the electrode unit 12-16, and the signal ends 14-2 of the respective temperature sensors 14; One end of the second dual-purpose signal line 19-2 is respectively and simultaneously connected to the dielectric elements 15 of the four electrode units 12 of the electrode unit 12-2, the electrode unit 12-7, the electrode unit 12-12, and the electrode unit 12-17, and the signal ends 14-2 of the respective temperature sensors 14; One end of the third dual-purpose signal line 19-3 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12 of the electrode unit 12-3, the electrode unit 12-8, and the electrode unit 12-13, and the signal ends 14-2 of the respective temperature sensors 14; One end of the fourth dual-purpose signal line 19-4 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12 of the electrode unit 12-4, the electrode unit 12-9, and the electrode unit 12-14, and the signal ends 14-2 of the respective temperature sensors 14; One end of the fifth dual-purpose signal line 19-5 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12 of the electrode unit 12-5, the electrode unit 12-10, and the electrode unit 12-15, and the signal ends 14-2 of the temperature sensors 14. In short, each dual-purpose signal line 19 short-circuits in parallel the dielectric elements 15 of the respective electrode units 12 and the signal ends 14-2 of the respective temperature sensors 14 located in the same column group and is used to connect to the adapter 20.

[0114] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 of the adapter 20 are respectively and electrically connected in one-to-one correspondence with the first ground wire 18-1, the second ground wire 18-2, the third ground wire 18-3, and the fourth third ground wire 18-4 of the electrode plate 10B through the first connector 40B. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 on the adapter 20 are respectively and electrically connected in one-to-one correspondence with the first dual-purpose signal wire 19-1, the second dual-purpose signal wire 19-2, the third dual-purpose signal wire 19-3, the fourth dual-purpose signal wire 19-4, and the fifth dual-purpose signal wire 19-5 of the electrode plate 10B through the first connector 40B. The working mode of the tumor electric field treatment system formed by the electrode plate 10B, the adapter 20, and the electric field generator 30 is the same as that of the aforementioned tumor electric field treatment system 100. When all the grounding switches 25 are disconnected and the input ends 2 of all the bidirectional switching switches 26 are turned on and the acquisition ends 1 are disconnected, all the dual-purpose signal wires 19 are turned on with the AC signal wire 28, and all the electrode units 12 are connected to the AC signal; when the acquisition ends 1 of all the bidirectional switching switches 26 are turned on and the input ends 2 are disconnected, by sequentially turning on the grounding switches 25, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained in sequence.

[0115] Reference Figure 8As shown, the electrode sheet 10C of the fourth embodiment is provided with 17 electrode units 12, the same as the electrode sheet 10B of the third embodiment. However, the specific circuit connection arrangements of the respective electrode units 12 are different. The flexible printed circuit board 11C of the electrode sheet 10C also arranges these 17 electrode units 12 in four rows and five columns in terms of electrical connection. Only one row has 5 electrode units 12, and the remaining three rows each have 4 electrode units 12. The electrode sheet 10C includes 4 ground wires 18 and 5 dual-purpose signal lines 19. Each ground wire 18 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the respective electrode units 12 in the same row group. Each dual-purpose signal line 19 respectively shorts the dielectric elements 15 of the respective electrode units 12 in each column group and the signal terminals 14-2 of the respective temperature sensors 14, and is used to receive temperature detection signals or transmit alternating current signals. The 4 ground wires 18 of the electrode sheet 10C include a first ground wire 18-1, a second ground wire 18-2, a third ground wire 18-3, and a fourth ground wire 18-4. The first row group includes electrode units 12-1 to 12-5, the second row group includes electrode units 12-6 to 12-9, the third row group includes electrode units 12-10 to 12-13, and the fourth row group includes electrode units 12-14 to 12-17. Specifically, the first ground wire 18-1 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the five electrode units 12 from electrode unit 12-1 to electrode unit 12-5 in the first row group; the second ground wire 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the four electrode units 12 from electrode unit 12-6 to electrode unit 12-9 in the second row group, the third ground wire 18-3 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the four electrode units 12 from electrode unit 12-10 to electrode unit 12-13 in the third row group, and the fourth ground wire 18-4 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the four electrode units 12 from electrode unit 12-14 to electrode unit 12-17 in the fourth row group. In short, each ground wire 18 shorts and grounds the ground terminals 14-1 of the temperature sensors 14 of all the electrode units 12 in the corresponding row group.

[0116] The five-way dual-purpose signal line 19 of the electrode sheet 10C includes a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is respectively and simultaneously connected to the dielectric elements 15 of the four electrode units 12 of the electrode unit 12-1, the electrode unit 12-6, the electrode unit 12-10, and the electrode unit 12-14, and the signal ends 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is respectively and simultaneously connected to the dielectric elements 15 of the four electrode units 12 of the electrode unit 12-2, the electrode unit 12-7, the electrode unit 12-11, and the electrode unit 12-15, and the signal ends 14-2 of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is respectively and simultaneously connected to the dielectric elements 15 of the four electrode units 12 of the electrode unit 12-3, the electrode unit 12-8, the electrode unit 12-12, and the electrode unit 12-16, and the signal ends 14-2 of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is respectively and simultaneously connected to the dielectric elements 15 of the four electrode units 12 of the electrode unit 12-4, the electrode unit 12-9, the electrode unit 12-13, and the electrode unit 12-17, and the signal ends 14-2 of their respective temperature sensors 14; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 of one electrode unit 12 of the electrode unit 12-5 and the signal end 14-2 of its temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits in parallel the dielectric elements 15 of the respective electrode units 12 and the signal ends 14-2 of their respective temperature sensors 14 located in the same column group and is used to connect to the adapter 20.

[0117] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 of the adapter 20 are respectively and electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3, and the fourth grounding wire 18-4 of the electrode plate 10C through the first connector 40C in one-to-one correspondence. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, and the fifth bidirectional switch 26-5 of the adapter 20 are respectively and electrically connected to the first dual-purpose signal wire 19-1, the second dual-purpose signal wire 19-2, the third dual-purpose signal wire 19-3, the fourth dual-purpose signal wire 19-4, and the fifth dual-purpose signal wire 19-5 of the electrode plate 10C through the first connector 40C in one-to-one correspondence. The working mode of the tumor electric field treatment system formed by the electrode plate 10C, the adapter 20, and the electric field generator 30 is the same as that of the aforementioned tumor electric field treatment system 100. When all the grounding switches 25 are disconnected and the input ends 2 of all the bidirectional switches 26 are conducted and the acquisition ends 1 are disconnected, all the dual-purpose signal wires 19 are conducted with the AC signal wire 28, and all the electrode units 12 are connected to the AC signal; when the acquisition ends 1 of all the bidirectional switches 26 are conducted and the input ends 2 are disconnected, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained in sequence by conducting each grounding switch 25 in sequence.

[0118] Reference Figure 9 The tumor electric field treatment system 100D shown in the fifth embodiment of the present application is different from Figure 1 the tumor electric field treatment system 100 described therein in that: this embodiment uses the electrode plate 10D of the fifth embodiment and Figure 1 the adapter 20 shown therein is electrically connected to the electric field generator 30. The electrode plate 10D of this embodiment also has 4 pieces, and is respectively plugged into the first socket 42 of the adapter 20 through the first plug 41D provided at the end of each first cable 13D. Each electrode plate 10D also includes a plurality of electrode units 12D that are both axially symmetrically arranged and centrally symmetrically arranged, several connecting portions 111D located between adjacent electrode units 12, and a wiring portion 112D electrically connected to the first cable 13D; however, the wiring portion 112D extends outward from one electrode unit 12 toward the electrode array (not labeled) and is arranged perpendicular to a connecting portion 111D. The first cable 13D has 8-core wires.

[0119] The electrode unit 12D of the electrode sheet 10D has the same structure as the electrode unit 12 in the foregoing embodiment, except that the number of electrode units 12 in this embodiment is 13 and they are arranged in five rows and five columns in space. Specifically, two electrode units 12 are provided in each of the first row and the last row, and are located in the second column and the fourth column respectively; three electrode units 12 are provided in each of the middle three rows, and the 3 electrode units 12 in each row are located in the first column, the third column, and the fifth column respectively. There are 3 electrode units 12 at the center of the electrode array (not labeled), which are the 3 electrode units 12 located in the third column of the second row, the third column of the third row, and the third column of the third row respectively, and the rest are electrode units 12 located on the periphery of the electrode array (not labeled). Among the electrode units 12 located on the periphery, adjacent two electrode units 12 are connected by a connecting portion 111D. The electrode unit 12 located in the third column of the second row is connected to the adjacent electrode units 12 in the first row and the second row through the connecting portion 111D respectively. The electrode unit 12 located in the third column of the fourth row is connected to the adjacent electrode units 12 in the fourth row and the fifth row through the connecting portion 111D respectively. The electrode unit 12 located in the third column of the third row is also connected to the adjacent electrode units 12 in the row direction and the column direction through the connecting portion 111D. The electrode units 12 located on the periphery are connected in pairs by the connecting portion 111D to form an octagonal ring structure.

[0120] Figure 10 (A) is Figure 9 a transformation embodiment of the electrode sheet 10D shown in, in which the electrode unit 12D' of the electrode sheet 10D' in this embodiment is the same as Figure 9The electrode units 12D of the electrode sheet 10D shown in [reference] are the same in spatial arrangement, and the connection parts 111D' connecting to the electrode unit 12D' at the center are also the same. The only difference is that: in the electrode sheet 10D' of this transformation embodiment, some adjacent electrode units 12D' located at the periphery are connected by the connection part 111D'; some adjacent electrode units 12D' located at the periphery are arranged in a disconnected state, and the connection part 111D' is not provided. Specifically, the two electrode units 12D' in the first row are arranged in a disconnected state, the two electrode units 12D' in the last row are arranged in a disconnected state, the two electrode units 12D' between the first column of the second row and the second column of the first row are arranged in a disconnected state, the two electrode units 12D' between the first column of the third row and the first column of the fourth row are arranged in a disconnected state, the two electrode units 12D' between the fifth column of the second row and the fifth column of the third row are arranged in a disconnected state, and the two electrode units 12D' between the fifth column of the fourth row and the fourth column of the fifth row are arranged in a disconnected state. A first gap D1' is formed between two adjacent electrode units 12D' that are arranged in a disconnected state and in adjacent columns, and a second gap D2' is formed between two adjacent electrode units 12D' that are arranged in a disconnected state and in adjacent rows. The settings of the first gap D1' and the second gap D2' can prevent the electrode sheet 10D' from generating wrinkles during application, affecting the overall attachment effect of the electrode sheet.

[0121] Figure 10 (B) is similar to Figure 10 (A), and it is also Figure 9 a transformation embodiment of the electrode sheet 10D shown in [reference]. The electrode units 12D'' of the electrode sheet 10D'' in this embodiment are the same in spatial arrangement as the electrode units 12D of the electrode sheet 10D shown in Figure 9 [reference]. The only difference is that: in the electrode sheet 10D'' of this transformation embodiment, the two electrode units 12D'' in the first row are arranged in a disconnected state, the two electrode units 12D'' in the last row are arranged in a disconnected state, the two electrode units 12D'' between the first column and the third column of the second row are arranged in a disconnected state, and the two electrode units 12D' between the third column and the fifth column of the fourth row are arranged in a disconnected state.

[0122] Figure 11 For Figure 9 the electrode sheet 10D of the fifth embodiment of the tumor electric field treatment system 100D shown in [reference] or its transformation embodiments 10D' and 10D'' and Figure 1Schematic diagram of the circuit connection of the adapter 20 of the first embodiment shown in the figure. The circuit description is given below by taking the electrode sheet 10D in the fifth embodiment as an example. In terms of electrical connection, the flexible circuit board 11D of the electrode sheet 10D arranges these 13 electrode units 12 in three rows and five columns, where each of the two rows has 5 electrode units 12, and the remaining row has 3 electrode units 12. The electrode sheet 10D includes 3 ground wires 18 and 5 dual-purpose signal lines 19. Each ground wire 18 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12 in the same row group. Each dual-purpose signal line 19 shorts the dielectric elements 15 of the electrode units 12 in each column group and the signal terminals 14-2 of the temperature sensors 14 respectively, and is used to receive temperature detection signals or transmit alternating current signals.

[0123] The 3 ground wires 18 of the electrode sheet 10D are respectively the first ground wire 18-1, the second ground wire 18-2, and the third ground wire 18-3. Among the 3 row groups of the electrode sheet 10D, the first row group includes electrode units 12-1 to electrode units 12-5, the second row group includes electrode units 12-6 to electrode units 12-10, and the third row group includes electrode units 12-11 to electrode units 12-13. Specifically, the first ground wire 18-1 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-1 to electrode units 12-5 in the first row group; the second ground wire 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-6 to electrode units 12-10 in the second row group; the third ground wire 18-3 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-11 to electrode units 12-13 in the third row group. In short, each ground wire 18 shorts and grounds the ground terminals 14-1 of the temperature sensors 14 of all the electrode units 12 in the corresponding row group.

[0124] The five-way dual-purpose signal line 19 of the electrode sheet 10D includes a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12 of the electrode unit 12-1, the electrode unit 12-6, and the electrode unit 12-11, and the signal ends 14-2 of the respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12 of the electrode unit 12-2, the electrode unit 12-7, and the electrode unit 12-12, and the signal ends 14-2 of the respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12 of the electrode unit 12-3, the electrode unit 12-8, and the electrode unit 12-13, and the signal ends 14-2 of the respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is respectively and simultaneously connected to the dielectric elements 15 of the two electrode units 12 of the electrode unit 12-4 and the electrode unit 12-9, and the signal ends 14-2 of the respective temperature sensors 14; one end of the fifth dual-purpose signal line 19-5 is respectively and simultaneously connected to the dielectric elements 15 of the two electrode units 12 of the electrode unit 12-5 and the electrode unit 12-10, and the signal ends 14-2 of the respective temperature sensors 14. In short, each dual-purpose signal line 19 short-circuits in parallel the dielectric elements 15 of the respective electrode units 12 located in the same column group and the signal ends 14-2 of the respective temperature sensors 14 and is used to connect to the adapter 20.

[0125] The first ground switch 25-1, the second ground switch 25-2, and the third ground switch 25-3 of the adapter 20 are respectively and electrically connected to the first ground wire 18-1, the second ground wire 18-2, and the third ground wire 18-3 of the electrode sheet 10D through the first connector 40D in one-to-one correspondence, and the fourth ground switch 25-4 is in an idle open state. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, and the fifth bidirectional switch 26-5 of the adapter 20 are respectively and electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 of the electrode sheet 10D through the first connector 40D in one-to-one correspondence.

[0126] The working mode of the tumor electric field therapy system formed by the electrode patch 10D, the adapter 20, and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. When all the grounding switches 25 are disconnected, the input ends 2 of all the bidirectional switching switches 26 are conducting, and the acquisition ends 1 are disconnected, all the dual-purpose signal lines 19 are conducting with the AC signal line 28, and all the electrode units 12 are connected to the AC signal. When the acquisition ends 1 of all the bidirectional switching switches 26 are conducting and the input ends 2 are disconnected, by sequentially conducting the grounding switches 25, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained in sequence. Among them, no operation is required for the grounding switches 25 in the idle and disconnected state.

[0127] Figure 12 as shown Figure 9 the electrode patch 10D of the fifth embodiment shown in Figure 10 the electrode patches 10D', 10D" shown in Figure 1 another circuit connection diagram of the adapter 20 of the first embodiment shown in

[0128] The five-way dual-purpose signal line 19 of the electrode sheet 10E includes a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12, namely the electrode unit 12-1, the electrode unit 12-5, and the electrode unit 12-9, and the signal terminals 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12, namely the electrode unit 12-2, the electrode unit 12-6, and the electrode unit 12-10, and the signal terminals 14-2 of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12, namely the electrode unit 12-3, the electrode unit 12-7, and the electrode unit 12-11, and the signal terminals 14-2 of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12, namely the electrode unit 12-4, the electrode unit 12-8, and the electrode unit 12-12, and the signal terminals 14-2 of their respective temperature sensors 14; one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 of the electrode unit 12-13 and the signal terminal 14-2 of its temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits in parallel the dielectric elements 15 of the respective electrode units 12 located in the same column group and the signal terminals 14-2 of their respective temperature sensors 14 and is used to connect to the adapter 20.

[0129] The first ground switch 25-1, the second ground switch 25-2, and the third ground switch 25-3 of the adapter 20 are respectively and electrically connected to the first ground wire 18-1, the second ground wire 18-2, and the third ground wire 18-3 of the electrode sheet 10E through the first connector 40E in one-to-one correspondence, and the fourth ground switch 25-4 is in an idle open state. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, and the fifth bidirectional switch 26-5 of the adapter 20 are respectively and electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 of the electrode sheet 10E through the first connector 40E in one-to-one correspondence.

[0130] The working mode of the tumor electric field therapy system formed by the electrode patch 10E, the adapter 20, and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. When all the grounding switches 25 are disconnected and the input terminals 2 of all the bidirectional switching switches 26 are conducting while the acquisition terminals 1 are disconnected, all the dual-purpose signal lines 19 are conducting with the AC signal line 28, and all the electrode units 12 are connected to the AC signal. When the acquisition terminals 1 of all the bidirectional switching switches 26 are conducting and the input terminals 2 are disconnected, by sequentially conducting the grounding switches 25, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained in sequence. Among them, no operation is required for the grounding switches 25 in the idle disconnected state.

[0131] Figure 13 Similar to Figure 12 it is also a transformation embodiment of the electrode patch 10D shown in Figure 9 or the electrode patch 10D shown in Figure 10 and another circuit connection schematic diagram of the adapter 20 shown in Figure 1 Refer to Figure 13As shown, the electrode patch 10F of the tumor electric field therapy system of the seventh embodiment has 13 electrode units 12, the same as the electrode patch 10D of the tumor electric field therapy system of the fifth embodiment, but the specific circuit arrangement is different. The flexible circuit board 11F of the electrode patch 10F arranges these 13 electrode units 12 in four rows and four columns in terms of electrical connection, where each of three rows has 4 electrode units 12, and the remaining row has 1 electrode unit 12. The electrode patch 10F includes 4 ground wires 18 and 4 dual-purpose signal lines 19. Each ground wire 18 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12 in the same row group. Each dual-purpose signal line 19 shorts the dielectric elements 15 of the electrode units 12 in the corresponding column group and the signal terminals 14-2 of the temperature sensors 14 respectively, for receiving temperature detection signals or transmitting alternating current signals. The 4 ground wires 18 of the electrode patch 10F include a first ground wire 18-1, a second ground wire 18-2, a third ground wire 18-3, and a fourth ground wire 18-4. The first row group includes electrode units 12-1 to 12-4, the second row group includes electrode units 12-5 to 12-8, the third row group includes electrode units 12-9 to 12-12, and the fourth row group includes electrode unit 12-13. Specifically, the first ground wire 18-1 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-1 to 12-4 in the first row group; the second ground wire 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-5 to 12-8 in the second row group, the third ground wire 18-3 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-9 to 12-12 in the third row group, and the fourth ground wire 18-4 is used to ground the ground terminal 14-1 of the temperature sensor 14 of the electrode unit 12-13 in the fourth row group. In short, each ground wire 18 shorts and grounds the ground terminals 14-1 of the temperature sensors 14 of all the electrode units 12 in each row group.

[0132] The four-way dual-purpose signal line 19 of the electrode sheet 10F includes a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, and a fourth dual-purpose signal line 19-4. One end of the first dual-purpose signal line 19-1 is respectively and simultaneously connected to the dielectric elements 15 of the four electrode units 12, namely the electrode unit 12-1, the electrode unit 12-5, the electrode unit 12-9, and the electrode unit 12-13, and the signal terminals 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12, namely the electrode unit 12-2, the electrode unit 12-6, and the electrode unit 12-10, and the signal terminals 14-2 of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12, namely the electrode unit 12-3, the electrode unit 12-7, and the electrode unit 12-11, and the signal terminals 14-2 of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12, namely the electrode unit 12-4, the electrode unit 12-8, and the electrode unit 12-12, and the signal terminals 14-2 of their respective temperature sensors 14. In short, each dual-purpose signal line 19 short-circuits in parallel the dielectric elements 15 of the respective electrode units 12 located in the same column group and the signal terminals 14-2 of their respective temperature sensors 14 and is used to connect to the adapter 20.

[0133] The first ground switch 25-1, the second ground switch 25-2, the third ground switch 25-3, and the fourth ground switch 25-4 of the adapter 20 are respectively and electrically connected to the first ground wire 18-1, the second ground wire 18-2, the third ground wire 18-3, and the fourth ground wire 18-4 of the electrode sheet 10F through the first connector 40F in one-to-one correspondence. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, and the fourth bidirectional switching switch 26-4 of the adapter 20 are respectively and electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, and the fourth dual-purpose signal line 19-4 through the first connector 40F in one-to-one correspondence, and the fifth bidirectional switching switch 26-5 is in an idle and open state.

[0134] The working mode of the tumor electric field therapy system formed by the electrode patch 10F, the adapter 20, and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. When all the grounding switches 25 are disconnected and the input terminals 2 of all the bidirectional switching switches 26 are conducting while the acquisition terminals 1 are disconnected, all the dual-purpose signal lines 19 are conducting with the AC signal line 28, and all the electrode units 12 are connected to the AC signal. When the acquisition terminals 1 of all the bidirectional switching switches 26 are conducting and the input terminals 2 are disconnected, the grounding switches 25 are sequentially conducted to sequentially obtain the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group. Among them, no operation is required for the bidirectional switching switches 26 in the idle disconnected state.

[0135] Figure 14 Similar to Figure 13 it is also a transformation embodiment for the electrode patch 10D shown in Figure 9 or the electrode patch 10D shown in Figure 10 and another circuit connection schematic diagram of the adapter 20 shown in Figure 1 Refer to Figure 14As shown, the electrode patch 10G of the tumor electro-field therapy system in the eighth embodiment also has 13 electrode units 12, but the specific circuit layout is different. The flexible circuit board 11G of the electrode patch 10G arranges these 13 electrode units 12 in four rows and four columns in terms of electrical connection. Among them, each of the three rows has 3 electrode units 12, and the remaining row has 4 electrode units 12. The electrode patch 10G includes 4 ground wires 18 and 4 dual-purpose signal lines 19. Each ground wire 18 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12 in the same row group. Each dual-purpose signal line 19 respectively shorts the dielectric elements 15 of the electrode units 12 in the corresponding column group and the signal terminals 14-2 of the temperature sensors 14, and is used to receive temperature detection signals or transmit alternating current signals. The 4 ground wires 18 of the electrode patch 10G include a first ground wire 18-1, a second ground wire 18-2, a third ground wire 18-3, and a fourth ground wire 18-4. The first row group includes electrode units 12-1 to electrode units 12-3, the second row group includes electrode units 12-4 to electrode units 12-6, the third row group includes electrode units 12-7 to electrode units 12-9, and the fourth row group includes electrode units 12-10 to electrode units 12-13. Specifically, the first ground wire 18-1 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-1 to electrode units 12-3 in the first row group; the second ground wire 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-4 to electrode units 12-6 in the second row group, the third ground wire 18-3 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-7 to electrode units 12-9 in the third row group, and the fourth ground wire 18-4 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-10 to electrode units 12-13 in the fourth row group. In short, each ground wire 18 shorts and grounds the ground terminals 14-1 of the temperature sensors 14 of all the electrode units 12 in the corresponding row group.

[0136] The four-way dual-purpose signal line 19 of the electrode sheet 10G includes a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, and a fourth dual-purpose signal line 19-4. One end of the first dual-purpose signal line 19-1 is respectively and simultaneously connected to the dielectric elements 15 of the four electrode units 12, namely the electrode unit 12-1, the electrode unit 12-4, the electrode unit 12-7, and the electrode unit 12-10, and the signal terminals 14-2 of the respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is respectively and simultaneously connected to the dielectric elements 15 of the four electrode units 12, namely the electrode unit 12-2, the electrode unit 12-5, the electrode unit 12-8, and the electrode unit 12-11, and the signal terminals 14-2 of the respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is respectively and simultaneously connected to the dielectric elements 15 of the four electrode units 12, namely the electrode unit 12-3, the electrode unit 12-6, the electrode unit 12-9, and the electrode unit 12-12, and the signal terminals 14-2 of the respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is connected to the dielectric element 15 of the electrode unit 12-13 and the signal terminal 14-2 of the temperature sensor 14. In short, each four-way dual-purpose signal line 19 short-circuits in parallel the dielectric elements 15 of the respective electrode units 12 located in the same column group and the signal terminals 14-2 of the respective temperature sensors 14 and is used to connect to the adapter 20.

[0137] The first ground switch 25-1, the second ground switch 25-2, the third ground switch 25-3, and the fourth ground switch 25-4 of the adapter 20 are respectively and electrically connected to the first ground wire 18-1, the second ground wire 18-2, the third ground wire 18-3, and the fourth ground wire 18-4 of the electrode sheet 10G through the first connector 40G in one-to-one correspondence. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, and the fourth bidirectional switch 26-4 of the adapter 20 are respectively and electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, and the fourth dual-purpose signal line 19-4 through the first connector 40G in one-to-one correspondence, and the fifth bidirectional switch 26-5 is in an idle open state.

[0138] The working mode of the tumor electric field therapy system formed by the electrode patch 10G, the adapter 20 and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. When all the grounding switches 25 are disconnected and the input ends 2 of all the bidirectional switching switches 26 are conducted while the acquisition ends 1 are disconnected, all the dual-purpose signal lines 19 are conducted with the AC signal line 28, and all the electrode units 12 are connected to the AC signal. When the acquisition ends 1 of all the bidirectional switching switches 26 are conducted and the input ends 2 are disconnected, the temperature detection signals of the temperature sensors 14 of the respective electrode units 12 in each row group can be obtained by sequentially conducting the respective grounding switches 25. Among them, no operation needs to be performed on the bidirectional switching switches 26 in the idle and disconnected state.

[0139] Reference Figure 15 and Figure 16 As shown, the main difference between the tumor electric field therapy system 100H in this embodiment and the tumor electric field therapy system 100 is that the electrode patch 10H of the ninth embodiment has 9 electrode units 12. In terms of spatial arrangement, the 9 electrode units 12 are arranged in a three-row and three-column array. In terms of electrical connection, the flexible circuit board 11H of the electrode patch 10H arranges the 9 electrode units 12 into two rows and five columns, where one row has 5 electrode units 12 and the other row has 4 electrode units 12. The electrode patch 10H includes 2 ground wires 18 and 5 dual-purpose signal lines 19. Each ground wire 18 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the respective electrode units 12 in the same row group. Each dual-purpose signal line 19 shorts the dielectric elements 15 of the respective electrode units 12 in each column group and the signal terminals 14-2 of the respective temperature sensors 14, and is used to receive temperature detection signals or transmit AC signals. The 2 ground wires 18 of the electrode patch 10H are the first ground wire 18-1 and the second ground wire 18-2 respectively. In the 2 row groups of the electrode patch 10H, the first row group includes electrode units 12-1 to electrode units 12-5, and the second row group includes electrode units 12-6 to electrode units 12-9. Specifically, the first ground wire 18-1 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-1 to electrode units 12-5 in the first row group; the second ground wire 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-6 to electrode units 12-9 in the second row group. In short, each ground wire 18 shorts and grounds the ground terminals 14-1 of the temperature sensors 14 of all the electrode units 12 in the corresponding row group.

[0140] The five-way dual-purpose signal line 19 of the electrode sheet 10H includes a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is respectively and simultaneously connected to the dielectric elements 15 of the two electrode units 12 of the electrode unit 12-1 and the electrode unit 12-6 and the signal terminals 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is respectively and simultaneously connected to the dielectric elements 15 of the two electrode units 12 of the electrode unit 12-2 and the electrode unit 12-7 and the signal terminals 14-2 of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is respectively and simultaneously connected to the dielectric elements 15 of the two electrode units 12 of the electrode unit 12-3 and the electrode unit 12-8 and the signal terminals 14-2 of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is respectively and simultaneously connected to the dielectric elements 15 of the two electrode units 12 of the electrode unit 12-4 and the electrode unit 12-9 and the signal terminals 14-2 of their respective temperature sensors 14; one end of the fifth dual-purpose signal line 19-5 is simultaneously connected to the dielectric element 15 of the electrode unit 12-5 and the signal terminal 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits in parallel the dielectric elements 15 of the respective electrode units 12 located in the same column group and the signal terminals 14-2 of their respective temperature sensors 14 and is used to connect to the adapter 20.

[0141] The first ground switch 25-1 and the second ground switch 25-2 of the adapter 20 are respectively and electrically connected to the first ground wire 18-1 and the second ground wire 18-2 of the electrode sheet 10H through the first connector 40H in a one-to-one correspondence, and the third ground switch 25-3 and the fourth ground switch 25-4 are in an idle and open state. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4, and the fifth bidirectional switch 26-5 of the adapter 20 are respectively and electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4, and the fifth dual-purpose signal line 19-5 through the first connector 40H in a one-to-one correspondence.

[0142] The working mode of the tumor electric field therapy system formed by the electrode patch 10H, the adapter 20, and the electric field generator 30 is the same as that of the aforementioned tumor electric field therapy system 100. When all the grounding switches 25 are disconnected, the input ends 2 of all the bidirectional switching switches 26 are turned on, and the acquisition ends 1 are disconnected, all the dual-purpose signal lines 19 are conducted with the AC signal line 28, and all the electrode units 12 are connected to the AC signal. When the acquisition ends 1 of all the bidirectional switching switches 26 are turned on and the input ends 2 are disconnected, the grounding switches 25 are sequentially turned on to sequentially obtain the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group. Among them, no operation is required for the grounding switches 25 in the idle disconnected state.

[0143] Reference Figure 17 As shown, the electrode patch 10J of the tenth embodiment also has 9 electrode units 12. In terms of electrical connection, the flexible circuit board 11J of the electrode patch 10J arranges these 9 electrode units 12 in three rows and three columns, with each row having 3 electrode units 12. The electrode patch 10J includes 3 ground wires 18 and 3 dual-purpose signal lines 19. Each ground wire 18 is used to ground the ground terminals 14-1 of the temperature sensors 14 of each electrode unit 12 in the corresponding row group. Each dual-purpose signal line 19 shorts the dielectric elements 15 of each electrode unit 12 and the signal terminals 14-2 of each temperature sensor 14 in the corresponding column group, and is used to receive the temperature detection signal or transmit the AC signal. The 3 ground wires 18 of the electrode patch 10J are respectively the first ground wire 18-1, the second ground wire 18-2, and the third ground wire 18-3. In the 3 row groups of the electrode patch 10J, the first row group includes the electrode units 12-1 to 12-3, the second row group includes the electrode units 12-4 to 12-6, and the third row group includes the electrode units 12-7 to 12-9. Specifically, the first ground wire 18-1 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-1 to 12-3 in the first row group; the second ground wire 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-4 to 12-6 in the second row group, and the third ground wire 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-7 to 12-9 in the third row group. In short, each ground wire 18 shorts and grounds the ground terminals 14-1 of the temperature sensors 14 of all the electrode units 12 in the corresponding row group.

[0144] The three-way dual-purpose signal line 19 of the electrode sheet 10J includes a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, and a third dual-purpose signal line 19-3. One end of the first dual-purpose signal line 19-1 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12 of the electrode unit 12-1, the electrode unit 12-4, and the electrode unit 12-7, and the signal terminals 14-2 of the respective temperature sensors 14; One end of the second dual-purpose signal line 19-2 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12 of the electrode unit 12-2, the electrode unit 12-5, and the electrode unit 12-8, and the signal terminals 14-2 of the respective temperature sensors 14; One end of the third dual-purpose signal line 19-3 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12 of the electrode unit 12-3, the electrode unit 12-6, and the electrode unit 12-9, and the signal terminals 14-2 of the respective temperature sensors 14. In short, each three-way dual-purpose signal line 19 short-circuits in parallel the dielectric elements 15 of the respective electrode units 12 located in the same column group and the signal terminals 14-2 of the respective temperature sensors 14 and is used to connect to the adapter 20.

[0145] The first ground switch 25-1, the second ground switch 25-2, and the third ground switch 25-3 of the adapter 20 are respectively and electrically connected to the first ground wire 18-1, the second ground wire 18-2, and the third ground wire 18-3 in one-to-one correspondence through the first connector 40J, and the fourth ground switch 25-4 is in an idle open state. The first bidirectional switch 26-1, the second bidirectional switch 26-2, and the third bidirectional switch 26-3 of the adapter 20 are respectively and electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, and the third dual-purpose signal line 19-3 in one-to-one correspondence through the first connector 40J, and the fourth bidirectional switch 26-4 and the fifth bidirectional switch 26-5 are both in an idle open state.

[0146] The working mode of the tumor electric field treatment system formed by the electrode sheet 10J, the adapter 20, and the electric field generator 30 is the same as that of the aforementioned tumor electric field treatment system 100. When all ground switches 25 are disconnected and the input ends 2 of all bidirectional switches 26 are turned on and the acquisition ends 1 are disconnected, all dual-purpose signal lines 19 are turned on to the AC signal line 28, and all electrode units 12 are connected to the AC signal; when the acquisition ends 1 of all bidirectional switches 26 are turned on and the input ends 2 are disconnected, by sequentially turning on the respective ground switches 25, the temperature detection signals of the temperature sensors 14 of the respective electrode units 12 in each row group can be obtained in sequence. Among them, no operation is required for the ground switch 25 in the idle open state and the bidirectional switch 26 in the idle open state.

[0147] In the tumor electro-field therapy system of the present application, the flexible circuit boards (11, 11A, 11B, 11C, 11D, 11E, 11F, 11G, 11H, 11J) of each electrode plate (10, 10A, 10B, 10C, 10D, 10D’, 10D”, 10E, 10F, 10G, 10H, 10J) electrically connect their electrode units 12 into multiple rows and columns. And the grounding ends 14-1 of the temperature sensors 14 of the electrode units 12 in the same row are electrically connected to the same ground wire 18. After the dielectric elements 15 of the electrode units 12 in the same column and the signal ends 14-2 of their respective temperature sensors 14 are short-circuited, they are electrically connected to the same dual-purpose signal wire 19. The adapter 20 is provided with a plurality of grounding switches 25 and a plurality of bidirectional switching switches 26. The respective ground wires 18 of the electrode plates (10, 10A, 10B, 10C, 10D, 10D’, 10D”, 10E, 10F, 10G, 10H, 10J) are respectively and electrically connected to the corresponding grounding switches 25 one by one, and the respective dual-purpose signal wires 19 are respectively and electrically connected to the corresponding bidirectional switching switches 26 one by one. Among them, the number of grounding switches 25 is greater than or equal to the number of ground wires 18, and the number of bidirectional switching switches 26 is greater than or equal to the number of dual-purpose signal wires 19. Therefore, the adapter 20 can be adapted to a variety of electrode plates (10, 10A, 10B, 10C, 10D, 10D’, 10D”, 10E, 10F, 10G, 10H, 10J), and there are grounding switches 25 in an idle and disconnected state and / or bidirectional switching switches 26 in an idle and disconnected state.

[0148] In the previous embodiment, the number of grounding switches 25 corresponding to each electrode plate 10 of the adapter 20 is fixed at 4, and the number of bidirectional switching switches 26 corresponding to each electrode plate 10 is fixed at 5, which can be applicable to a variety of different electrode plates 10. However, in some usage cases, there will be grounding switches 25 in an idle and disconnected state and / or bidirectional switching switches 26 in an idle and disconnected state, and the program control will be relatively complex. Another way is to provide a specific adapter for the number of ground wires 18 and the number of dual-purpose signal wires 19 of the electrode plate to avoid the occurrence of grounding switches 25 in an idle and disconnected state and / or bidirectional switching switches 26 in an idle and disconnected state, which is convenient for program control. For this reason, the present application also provides other embodiments of some electrode plates and adapters, which will be described separately below.

[0149] Refer to Figure 18As shown, the electrode sheet 10K of the eleventh embodiment is provided with 20 electrode units, and its flexible circuit board 11K electrically connects these 20 electrode units 12 into a layout of five rows and four columns, with each row having 4 electrode units 12. The electrode sheet 10K includes 5 ground wires 18 and 4 dual-purpose signal lines 19. Each ground wire 18 is used to ground the ground terminals 14-1 of the temperature sensors 14 of each electrode unit 12 in the corresponding row group. Each dual-purpose signal line 19 respectively shorts the dielectric elements 15 of each electrode unit 12 in the corresponding column group and the signal terminals 14-2 of each temperature sensor 14, and is used to receive temperature detection signals or transmit alternating current signals. The 5 ground wires 18 of the electrode sheet 10K include a first ground wire 18-1, a second ground wire 18-2, a third ground wire 18-3, a fourth ground wire 18-4, and a fifth ground wire 18-5. The first row group includes electrode units 12-1 to electrode unit 12-4, the second row group includes electrode units 12-5 to electrode unit 12-8, the third row group includes electrode units 12-9 to electrode unit 12-12, the fourth row group includes electrode units 12-13 to electrode unit 12-16, and the fifth row group includes electrode units 12-17 to electrode unit 12-20. Specifically, the first ground wire 18-1 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-1 to electrode unit 12-4 in the first row group; the second ground wire 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-5 to electrode unit 12-8 in the second row group; the third ground wire 18-3 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-9 to electrode unit 12-12 in the third row group; the fourth ground wire 18-4 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-13 to electrode unit 12-16 in the fourth row group; the fifth ground wire 18-5 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-17 to electrode unit 12-20 in the fourth row group. In short, each ground wire 18 shorts and grounds the ground terminals 14-1 of the temperature sensors 14 of all the electrode units 12 in each row group.

[0150] The four-way dual-purpose signal line 19 of the electrode sheet 10K includes a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, and a fourth dual-purpose signal line 19-4. One end of the first dual-purpose signal line 19-1 is respectively and simultaneously connected to the dielectric elements 15 of each of the five electrode units 12, namely the electrode unit 12-1, the electrode unit 12-5, the electrode unit 12-9, the electrode unit 12-13, and the electrode unit 12-17, and the signal terminals 14-2 of their respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is respectively and simultaneously connected to the dielectric elements 15 of each of the five electrode units 12, namely the electrode unit 12-2, the electrode unit 12-6, the electrode unit 12-10, the electrode unit 12-14, and the electrode unit 12-18, and the signal terminals 14-2 of their respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is respectively and simultaneously connected to the dielectric elements 15 of each of the five electrode units 12, namely the electrode unit 12-3, the electrode unit 12-7, the electrode unit 12-11, the electrode unit 12-15, and the electrode unit 12-19, and the signal terminals 14-2 of their respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is respectively and simultaneously connected to the dielectric elements 15 of each of the five electrode units 12, namely the electrode unit 12-4, the electrode unit 12-8, the electrode unit 12-12, the electrode unit 12-16, and the electrode unit 12-20, and the signal terminals 14-2 of their respective temperature sensors 14. In short, each dual-purpose signal line 19 short-circuits in parallel the dielectric elements 15 of each electrode unit 12 located in the corresponding column group and the signal terminals 14-2 of their respective temperature sensors 14 and is used to connect to the adapter 20.

[0151] Reference Figure 18 , this application provides an adapter 20K of the second embodiment, which can be adapted to the electrode sheet 10K of the eleventh embodiment, and in combination with Figure 20As shown, the adapter 20K also includes: a first controller 22, multiple groups of analog-to-digital converters 23 connected to the first controller 22, multiple groups of voltage-dividing resistors 24 and multiple groups of grounding switches 25 corresponding to the multiple groups of analog-to-digital converters 23 one by one, multiple groups of bidirectional switching switches 26 connected to the multiple groups of analog-to-digital converters 23 one by one, a first communication unit 27, AC signal lines 28 connected to each group of bidirectional switching switches 26 one by one, and a first power module 29 connected to the first communication unit 27, the first controller 22, and the multiple groups of analog-to-digital converters 23 at the same time. The first power module 29 provides a DC power supply VCC for each electronic component of the adapter 20K. The adapter 20K also includes multiple circuit lines (not labeled). The difference between it and the adapter 20 of the foregoing first embodiment is that: each group of grounding switches 25 of the adapter 20K is provided with an additional fifth grounding switch 25-5, each group of bidirectional switching switches 26 is provided with one less fifth bidirectional switching switch 26-5, and the detection channel E corresponding to the fifth bidirectional switching switch 26-5 in each group of analog-to-digital converters 23 and the voltage-dividing resistor corresponding to the fifth bidirectional switching switch 26-5 in each group of voltage-dividing resistors 24 are reduced. For the other specific structures and working principles of the adapter 20K, please refer to the relevant specific descriptions of the foregoing adapter 20, which will not be elaborated here.

[0152] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, the fourth grounding switch 25-4, and the fifth grounding switch 25-5 of the adapter 20K are respectively and electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3, the fourth grounding wire 18-4, and the fifth grounding wire 18-5 of the electrode plate 10K through the first connector 40K one by one. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, and the fourth bidirectional switching switch 26-4 of the adapter 20K are respectively and electrically connected to the first dual-purpose signal wire 19-1, the second dual-purpose signal wire 19-2, the third dual-purpose signal wire 19-3, and the fourth dual-purpose signal wire 19-4 of the electrode plate 10K through the first connector 40K one by one. The working mode of the tumor electric field treatment system formed by the electrode plate 10K, the adapter 20K, and the electric field generator 30 is the same as that of the foregoing tumor electric field treatment system 100. When all the grounding switches 25 are disconnected and the input ends 2 of all the bidirectional switching switches 26 are conducting and the acquisition ends 1 are disconnected, all the dual-purpose signal wires 19 are conducting with the AC signal lines 28, and all the electrode units 12 are connected to the AC signal; when the acquisition ends 1 of all the bidirectional switching switches 26 are conducting and the input ends 2 are disconnected, by sequentially conducting each grounding switch 25, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained in sequence.

[0153] Refer to Figure 19As shown, the electrode sheet 10L of the twelfth embodiment is provided with 19 electrode units 12. The flexible circuit board 11L electrically connects and arranges these 19 electrode units 12 in four rows and five columns, where each of the four rows has 4 electrode units 12, and the remaining row has 3 electrode units 12. The electrode sheet 10L includes 5 ground wires 18 and 4 dual-purpose signal lines 19. Each ground wire 18 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12 in the corresponding row group. Each dual-purpose signal line 19 shorts the dielectric elements 15 of the electrode units 12 in the corresponding column group and the signal terminals 14-2 of the temperature sensors 14 respectively, and is used to receive temperature detection signals or transmit alternating current signals. The 5 ground wires 18 of the electrode sheet 10L include a first ground wire 18-1, a second ground wire 18-2, a third ground wire 18-3, a fourth ground wire 18-4, and a fifth ground wire 18-5. The first row group includes electrode units 12-1 to 12-4, the second row group includes electrode units 12-5 to 12-8, the third row group includes electrode units 12-9 to 12-12, the fourth row group includes electrode units 12-13 to 12-16, and the fifth row group includes electrode units 12-17 to 12-19. Specifically, the first ground wire 18-1 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-1 to 12-4 in the first row group; the second ground wire 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-5 to 12-8 in the second row group, the third ground wire 18-3 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-9 to 12-12 in the third row group, the fourth ground wire 18-4 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-13 to 12-16 in the fourth row group, and the fifth ground wire 18-5 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-17 to 12-19 in the fifth row group. In short, each ground wire 18 shorts and grounds the ground terminals 14-1 of the temperature sensors 14 of all the electrode units 12 in each row group.

[0154] The four-way dual-purpose signal line 19 of the electrode sheet 10L includes a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, and a fourth dual-purpose signal line 19-4. One end of the first dual-purpose signal line 19-1 is respectively and simultaneously connected to the dielectric elements 15 of the five electrode units 12 of the electrode unit 12-1, the electrode unit 12-5, the electrode unit 12-9, the electrode unit 12-13, and the electrode unit 12-17 and the signal terminals 14-2 of the respective temperature sensors 14; One end of the second dual-purpose signal line 19-2 is respectively and simultaneously connected to the dielectric elements 15 of the five electrode units 12 of the electrode unit 12-2, the electrode unit 12-6, the electrode unit 12-10, the electrode unit 12-14, and the electrode unit 12-18 and the signal terminals 14-2 of the respective temperature sensors 14; One end of the third dual-purpose signal line 19-3 is respectively and simultaneously connected to the dielectric elements 15 of the five electrode units 12 of the electrode unit 12-3, the electrode unit 12-7, the electrode unit 12-11, the electrode unit 12-15, and the electrode unit 12-19 and the signal terminals 14-2 of the respective temperature sensors 14; One end of the fourth dual-purpose signal line 19-4 is respectively and simultaneously connected to the dielectric elements 15 of the four electrode units 12 of the electrode unit 12-4, the electrode unit 12-8, the electrode unit 12-12, and the electrode unit 12-16 and the signal terminals 14-2 of the respective temperature sensors 14. In short, each dual-purpose signal line 19 short-circuits in parallel the dielectric elements 15 of the respective electrode units 12 located in the corresponding same column group and the signal terminals 14-2 of the respective temperature sensors 14 and is used to connect to the adapter 20K.

[0155] Reference Figure 19, the adapter 20K of the second embodiment can also be adapted to the electrode sheet 10L of the twelfth embodiment. The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, the fourth grounding switch 25-4 and the fifth grounding switch 25-5 of the adapter 20K are respectively and electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3, the fourth grounding wire 18-4 and the fifth grounding wire 18-5 of the electrode sheet 10L in one-to-one correspondence through the first connector 40L. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3 and the fourth bidirectional switching switch 26-4 of the adapter 20K are respectively and electrically connected to the first dual-purpose signal wire 19-1, the second dual-purpose signal wire 19-2, the third dual-purpose signal wire 19-3 and the fourth dual-purpose signal wire 19-4 of the electrode sheet 10L in one-to-one correspondence through the first connector 40L. The working mode of the tumor electric field treatment system formed by the electrode sheet 10L, the adapter 20K and the electric field generator 30 is the same as that of the aforementioned tumor electric field treatment system 100. When all the grounding switches 25 are disconnected and the input ends 2 of all the bidirectional switching switches 26 are conducted and the acquisition ends 1 are disconnected, all the dual-purpose signal wires 19 are conducted with the AC signal wire 28, and all the electrode units 12 are connected to the AC signal; when the acquisition ends 1 of all the bidirectional switching switches 26 are conducted and the input ends 2 are disconnected, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained in sequence by conducting each grounding switch 25 in sequence.

[0156] Reference Figure 21As shown, the electrode sheet 10M of the thirteenth embodiment is provided with 18 electrode units 12. In terms of electrical connection, the flexible circuit board 11M arranges these 18 electrode units 12 in three rows and six columns, with each row having 6 electrode units 12 respectively. The electrode sheet 10M includes 3 ground wires 18 and 6 dual-purpose signal lines 19. Each ground wire 18 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the respective electrode units 12 in the corresponding same-row group. Each dual-purpose signal line 19 shorts the dielectric elements 15 of the respective electrode units 12 in the corresponding same-column group and the signal terminals 14-2 of the respective temperature sensors 14, and is used to receive temperature detection signals or transmit alternating current signals. The 3 ground wires 18 of the electrode sheet 10M include a first ground wire 18-1, a second ground wire 18-2, and a third ground wire 18-3. The first row group includes electrode units 12-1 to 12-6, the second row group includes electrode units 12-7 to 12-12, and the third row group includes electrode units 12-13 to 12-18. Specifically, the first ground wire 18-1 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-1 to 12-6 in the first row group; the second ground wire 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-7 to 12-12 in the second row group; the third ground wire 18-3 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-13 to 12-18 in the third row group. In short, each ground wire 18 shorts and grounds the ground terminals 14-1 of the temperature sensors 14 of all the electrode units 12 in each row group.

[0157] The six-way dual-purpose signal line 19 of the electrode sheet 10M includes a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, a fifth dual-purpose signal line 19-5, and a sixth dual-purpose signal line 19-6. One end of the first dual-purpose signal line 19-1 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12 of the electrode unit 12-1, the electrode unit 12-7, and the electrode unit 12-13, and the signal terminals 14-2 of the respective temperature sensors 14; one end of the second dual-purpose signal line 19-2 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12 of the electrode unit 12-2, the electrode unit 12-8, and the electrode unit 12-14, and the signal terminals 14-2 of the respective temperature sensors 14; one end of the third dual-purpose signal line 19-3 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12 of the electrode unit 12-3, the electrode unit 12-9, and the electrode unit 12-15, and the signal terminals 14-2 of the respective temperature sensors 14; one end of the fourth dual-purpose signal line 19-4 is respectively and simultaneously connected to the dielectric elements 15 of the three electrode units 12 of the electrode unit 12-4, the electrode unit 12-10, and the electrode unit 12-16, and the signal terminals 14-2 of the respective temperature sensors 14; one end of the fifth dual-purpose signal line 19-5 is respectively connected to the dielectric elements 15 of the three electrode units 12 of the electrode unit 12-5, the electrode unit 12-11, and the electrode unit 12-17, and the signal terminals 14-2 of the temperature sensor 14; one end of the sixth dual-purpose signal line 19-6 is respectively connected to the dielectric elements 15 of the three electrode units 12 of the electrode unit 12-6, the electrode unit 12-12, and the electrode unit 12-18, and the signal terminals 14-2 of the temperature sensor 14. In short, each dual-purpose signal line 19 short-circuits in parallel the dielectric elements 15 of the respective electrode units 12 and the signal terminals 14-2 of the respective temperature sensors 14 located in the corresponding same column group and is used to connect to the adapter 20M.

[0158] Combine Figure 23As shown, the adapter 20M of the third embodiment is adapted to the electrode sheet 10M of the thirteenth embodiment. The adapter 20M also includes: a first controller 22, multiple groups of analog-to-digital converters 23 connected to the first controller 22, multiple groups of voltage-dividing resistors 24 and multiple groups of grounding switches 25 corresponding to the multiple groups of analog-to-digital converters 23 one by one, multiple groups of bidirectional switching switches 26 connected to the multiple groups of analog-to-digital converters 23 one by one, a first communication unit 27, AC signal lines 28 connected to each group of bidirectional switching switches 26 one by one, and a first power supply module 29 connected to the first communication unit 27, the first controller 22, and the multiple groups of analog-to-digital converters 23 at the same time. The first power supply module 29 provides a DC power supply VCC for each electronic component of the adapter 20M. The adapter 20M also includes multiple circuit lines (not labeled). The difference between it and the aforementioned adapter 20 is that each group of grounding switches 25 of the adapter 20M reduces the setting of a fourth grounding switch 25-4, each group of bidirectional switching switches 26 increases the setting of a sixth bidirectional switching switch 26-6, and increases the setting of a detection channel F corresponding to the sixth bidirectional switching switch 26-6 in each group of analog-to-digital converters 23 and increases the setting of a voltage-dividing resistor corresponding to the sixth bidirectional switching switch 26-6 in each group of voltage-dividing resistors 24. For the other specific structures and working principles of the adapter 20M, please refer to the relevant specific descriptions of the aforementioned adapter 20, which will not be elaborated here.

[0159] The first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 of the adapter 20M are respectively and electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, and the third grounding wire 18-3 of the electrode sheet 10M through a first connector 40M. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, the fifth bidirectional switching switch 26-5, and the sixth bidirectional switching switch 26-6 on the adapter 20M are respectively and electrically connected to the first dual-purpose signal wire 19-1, the second dual-purpose signal wire 19-2, the third dual-purpose signal wire 19-3, the fourth dual-purpose signal wire 19-4, the fifth dual-purpose signal wire 19-5, and the sixth dual-purpose signal wire 19-6 of the electrode sheet 10M through a first connector 40M. The working mode of the tumor electric field treatment system formed by the electrode sheet 10M, the adapter 20M, and the electric field generator 30 is the same as that of the previous tumor electric field treatment system 100. When all the grounding switches 25 are disconnected and the input ends 2 of all the bidirectional switching switches 26 are conducting and the acquisition ends 1 are disconnected, all the dual-purpose signal wires 19 are conducting with the AC signal lines 28, and all the electrode units 12 are connected to the AC signal; when the acquisition ends 1 of all the bidirectional switching switches 26 are conducting and the input ends 2 are disconnected, by sequentially conducting each grounding switch 25, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained in sequence.

[0160] Refer toFigure 22 As shown, the electrode sheet 10N of the fourteenth embodiment is provided with 17 electrode units 12. In terms of electrical connection, the flexible circuit board 11N arranges these 17 electrode units 12 in three rows and six columns, where each of the two rows has 6 electrode units 12, and the remaining one row has 5 electrode units 12. The electrode sheet 10N includes 3 ground wires 18 and 6 dual-purpose signal lines 19. Each ground wire 18 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12 in the same row group. Each dual-purpose signal line 19 respectively shorts the dielectric elements 15 of the electrode units 12 in the corresponding same column group and the signal terminals 14-2 of the temperature sensors 14, and is used to receive temperature detection signals or transmit alternating current signals. The 3 ground wires 18 of the electrode sheet 10N include a first ground wire 18-1, a second ground wire 18-2, and a third ground wire 18-3. The first row group includes electrode units 12-1 to electrode units 12-6, the second row group includes electrode units 12-7 to electrode units 12-12, and the third row group includes electrode units 12-13 to electrode units 12-17. Specifically, the first ground wire 18-1 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-1 to electrode units 12-6 in the first row group; the second ground wire 18-2 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-7 to electrode units 12-12 in the second row group, and the third ground wire 18-3 is used to ground the ground terminals 14-1 of the temperature sensors 14 of the electrode units 12-13 to electrode units 12-17 in the third row group. In short, each ground wire 18 shorts and grounds the ground terminals 14-1 of the temperature sensors 14 of all the electrode units 12 in the corresponding row group.

[0161] The six-way dual-purpose signal line 19 of the electrode sheet 10N includes a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4, a fifth dual-purpose signal line 19-5, and a sixth dual-purpose signal line 19-6. One end of the first dual-purpose signal line 19-1 is respectively and simultaneously connected to the dielectric elements 15 and the signal terminals 14-2 of the temperature sensors 14 of the three electrode units 12, namely the electrode unit 12-1, the electrode unit 12-7, and the electrode unit 12-13; one end of the second dual-purpose signal line 19-2 is respectively and simultaneously connected to the dielectric elements 15 and the signal terminals 14-2 of the temperature sensors 14 of the three electrode units 12, namely the electrode unit 12-2, the electrode unit 12-8, and the electrode unit 12-14; one end of the third dual-purpose signal line 19-3 is respectively and simultaneously connected to the dielectric elements 15 and the signal terminals 14-2 of the temperature sensors 14 of the three electrode units 12, namely the electrode unit 12-3, the electrode unit 12-9, and the electrode unit 12-15; one end of the fourth dual-purpose signal line 19-4 is respectively and simultaneously connected to the dielectric elements 15 and the signal terminals 14-2 of the temperature sensors 14 of the three electrode units 12, namely the electrode unit 12-4, the electrode unit 12-10, and the electrode unit 12-16; one end of the fifth dual-purpose signal line 19-5 is respectively and simultaneously connected to the dielectric elements 15 and the signal terminals 14-2 of the temperature sensors 14 of the three electrode units 12, namely the electrode unit 12-5, the electrode unit 12-11, and the electrode unit 12-17; one end of the sixth dual-purpose signal line 19-6 is respectively and simultaneously connected to the dielectric elements 15 and the signal terminals 14-2 of the temperature sensors 14 of the two electrode units 12, namely the electrode unit 12-6 and the electrode unit 12-12. In short, each dual-purpose signal line 19 short-circuits in parallel the dielectric elements 15 and the signal terminals 14-2 of the respective temperature sensors 14 of the electrode units 12 located in the same column group and is used to connect to the adapter 20M.

[0162] Reference Figure 22, the adapter 20M of the third embodiment can also be adapted to the electrode sheet 10N of the fourteenth embodiment. The first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 of the adapter 20M are respectively and electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, and the third grounding wire 18-3 of the electrode sheet 10N through the first connector 40N in one-to-one correspondence. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, the fifth bidirectional switching switch 26-5, and the sixth bidirectional switching switch 26-6 on the adapter 20M are respectively and electrically connected to the first dual-purpose signal wire 19-1, the second dual-purpose signal wire 19-2, the third dual-purpose signal wire 19-3, the fourth dual-purpose signal wire 19-4, the fifth dual-purpose signal wire 19-5, and the sixth dual-purpose signal wire 19-6 of the electrode sheet 10N through the first connector 40N in one-to-one correspondence. The working mode of the tumor electric field treatment system formed by the electrode sheet 10N, the adapter 20M, and the electric field generator 30 is the same as that of the aforementioned tumor electric field treatment system 100. When all the grounding switches 25 are disconnected and the input ends 2 of all the bidirectional switching switches 26 are conducting and the acquisition ends 1 are disconnected, all the dual-purpose signal wires 19 are conducting with the AC signal wire 28, and all the electrode units 12 are connected to the AC signal; when the acquisition ends 1 of all the bidirectional switching switches 26 are conducting and the input ends 2 are disconnected, by sequentially conducting each grounding switch 25, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained in sequence.

[0163] Reference Figure 24 and Figure 26 As shown in the figure, an adapter 20B of the fourth embodiment is provided to be adapted to the electrode sheet 10D of the aforementioned fifth embodiment. The adapter 20B also includes: a first controller 22, multiple groups of analog-to-digital converters 23 connected to the first controller 22, multiple groups of voltage dividing resistors 24 and multiple groups of grounding switches 25 corresponding to the multiple groups of analog-to-digital converters 23 one by one, multiple groups of bidirectional switching switches 26 connected to the multiple groups of analog-to-digital converters 23 one by one, a first communication unit 27, an AC signal wire 28 connected to each group of bidirectional switching switches 26 one by one, and a first power module 29 connected to the first communication unit 27, the first controller 22, and the multiple groups of analog-to-digital converters 23 at the same time. The first power module 29 provides a DC power supply VCC for each electronic component of the adapter 20B. There are also multiple circuit lines (not labeled) in the adapter 20B. The difference between it and the aforementioned adapter 20 is that: one fourth grounding switch 25-4 is reduced in each group of grounding switches 25 of the adapter 20B. For other specific structures and working principles of the adapter 20B, please refer to the relevant specific descriptions of the aforementioned adapter 20, which will not be elaborated here.

[0164] The first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 on the adapter 20B are respectively and electrically connected to the first ground wire 18-1, the second ground wire 18-2, and the third ground wire 18-3 of the electrode plate 10D through the first connector 40D'. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 on the adapter 20B are respectively and electrically connected to the first dual-purpose signal wire 19-1, the second dual-purpose signal wire 19-2, the third dual-purpose signal wire 19-3, the fourth dual-purpose signal wire 19-4, and the fifth dual-purpose signal wire 19-5 of the electrode plate 10D through the first connector 40D'. The working mode of the tumor electric field treatment system formed by the electrode plate 10D, the adapter 20B, and the electric field generator 30 is the same as that of the aforementioned tumor electric field treatment system 100. When all the grounding switches 25 are disconnected and the input ends 2 of all the bidirectional switching switches 26 are conducting and the acquisition ends 1 are disconnected, all the dual-purpose signal wires 19 are conducting with the AC signal wire 28, and all the electrode units 12 are connected to the AC signal; when the acquisition ends 1 of all the bidirectional switching switches 26 are conducting and the input ends 2 are disconnected, by sequentially conducting each grounding switch 25, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained in sequence.

[0165] Reference Figure 25 As shown in the figure, the adapter 20B of the fourth embodiment can also be adapted to the electrode plate 10E of the aforementioned sixth embodiment. The first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 on the adapter 20B are respectively and electrically connected to the first ground wire 18-1, the second ground wire 18-2, and the third ground wire 18-3 of the electrode plate 10E through the first connector 40E'. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4, and the fifth bidirectional switching switch 26-5 on the adapter 20B are respectively and electrically connected to the first dual-purpose signal wire 19-1, the second dual-purpose signal wire 19-2, the third dual-purpose signal wire 19-3, the fourth dual-purpose signal wire 19-4, and the fifth dual-purpose signal wire 19-5 of the electrode plate 10E through the first connector 40E'. The working mode of the tumor electric field treatment system formed by the electrode plate 10E, the adapter 20B, and the electric field generator 30 is the same as that of the aforementioned tumor electric field treatment system 100. When all the grounding switches 25 are disconnected and the input ends 2 of all the bidirectional switching switches 26 are conducting and the acquisition ends 1 are disconnected, all the dual-purpose signal wires 19 are conducting with the AC signal wire 28, and all the electrode units 12 are connected to the AC signal; when the acquisition ends 1 of all the bidirectional switching switches 26 are conducting and the input ends 2 are disconnected, by sequentially conducting each grounding switch 25, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained in sequence.

[0166] Reference Figure 27 and Figure 29 As shown, an adapter 20C of the fifth embodiment is provided for the electrode sheet 10F of the aforementioned seventh embodiment. The adapter 20C also includes: a first controller 22, multiple groups of analog-to-digital converters 23 connected to the first controller 22, multiple groups of voltage-dividing resistors 24 and multiple groups of grounding switches 25 corresponding one-to-one to the multiple groups of analog-to-digital converters 23, multiple groups of bidirectional switching switches 26 connected to the multiple groups of analog-to-digital converters 23 one-to-one, a first communication unit 27, AC signal lines 28 connected to each group of bidirectional switching switches 26 one-to-one, and a first power module 29 connected to the first communication unit 27, the first controller 22, and the multiple groups of analog-to-digital converters 23 at the same time. The first power module 29 provides a DC power supply VCC for each electronic component of the adapter 20C. There are also multiple circuit lines (not labeled) in the adapter 20C. The difference between it and the aforementioned adapter 20 is that each group of bidirectional switching switches 26 of the adapter 20C reduces the setting of a fifth bidirectional switching switch 26-5, and reduces the setting of the detection channel E corresponding to the fifth bidirectional switching switch 26-5 in each group of analog-to-digital converters 23 and reduces the setting of the voltage-dividing resistor corresponding to the fifth bidirectional switching switch 26-5 in each group of voltage-dividing resistors 24. For the other specific structures and working principles of the adapter 20C, please refer to the relevant specific descriptions of the aforementioned adapter 20, which will not be elaborated here.

[0167] The first grounding switch 25-1, the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 of the adapter 20C are respectively and electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, the third grounding wire 18-3, and the fourth grounding wire 18-4 of the electrode sheet 10F of the third embodiment through the first connector 40F'. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, and the fourth bidirectional switching switch 26-4 on the adapter 20C are respectively and electrically connected to the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, and the fourth dual-purpose signal line 19-4 through the first connector 40F'. The working mode of the tumor electric field treatment system formed by the electrode sheet 10F, the adapter 20C, and the electric field generator 30 is the same as that of the aforementioned tumor electric field treatment system 100. When all the grounding switches 25 are disconnected and the input ends 2 of all the bidirectional switching switches 26 are conducting and the acquisition ends 1 are disconnected, all the dual-purpose signal lines 19 are conducting with the AC signal lines 28, and all the electrode units 12 are connected to the AC signal; when the acquisition ends 1 of all the bidirectional switching switches 26 are conducting and the input ends 2 are disconnected, by sequentially conducting each grounding switch 25, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained in sequence.

[0168] Reference Figure 28 As shown, the adapter 20C of the fifth embodiment can be adapted to the electrode sheet 10G of the foregoing eighth embodiment. The first ground switch 25-1, the second ground switch 25-2, the third ground switch 25-3, and the fourth ground switch 25-4 on the adapter 20C are respectively and electrically connected to the first ground wire 18-1, the second ground wire 18-2, the third ground wire 18-3, and the fourth ground wire 18-4 of the electrode sheet 10G through the first connector 40G'. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, and the fourth bidirectional switch 26-4 on the adapter 20C are respectively and electrically connected to the first dual-purpose signal wire 19-1, the second dual-purpose signal wire 19-2, the third dual-purpose signal wire 19-3, and the fourth dual-purpose signal wire 19-4 through the first connector 40G'. Reference Figure 29 , the working mode of the tumor electric field treatment system formed by the electrode sheet 10G, the adapter 20C, and the electric field generator 30 is the same as that of the foregoing tumor electric field treatment system 100. When all the ground switches 25 are disconnected and the input ends 2 of all the bidirectional switches 26 are turned on and the acquisition ends 1 are disconnected, all the dual-purpose signal wires 19 are turned on to the AC signal wire 28, and all the electrode units 12 are connected to the AC signal; when the acquisition ends 1 of all the bidirectional switches 26 are turned on and the input ends 2 are disconnected, by sequentially turning on the ground switches 25, the temperature detection signals of the temperature sensors 14 of the respective electrode units 12 in each row group can be obtained in sequence.

[0169] Reference Figure 30 And Figure 31 As shown, an adapter 20D of the sixth embodiment adapted to the electrode sheet 10H of the foregoing ninth embodiment is provided. The adapter 20D also includes: a first controller 22, multiple groups of analog-to-digital converters 23 connected to the first controller 22, multiple groups of voltage dividing resistors 24 and multiple groups of ground switches 25 corresponding to the multiple groups of analog-to-digital converters 23 one by one, multiple groups of bidirectional switches 26 connected to the multiple groups of analog-to-digital converters 23 one by one, a first communication unit 27, an AC signal wire 28 connected to each group of bidirectional switches 26 one by one, and a first power supply module 29 connected to the first communication unit 27, the first controller 22, and the multiple groups of analog-to-digital converters 23 at the same time. The first power supply module 29 provides a DC power supply VCC for each electronic component of the adapter 20D. The adapter 20D also includes multiple circuit lines (not labeled) inside. The difference between it and the foregoing adapter 20 is that each group of ground switches 25 of the adapter 20D reduces the setting of a fourth ground switch 25-4 and a third ground switch 25-3. For the other specific structures and working principles of the adapter 20D, please refer to the relevant specific descriptions of the foregoing adapter 20, which will not be elaborated here.

[0170] The first grounding switch 25-1 and the second grounding switch 25-2 on the adapter 20D are respectively and electrically connected in one-to-one correspondence with the first grounding wire 18-1 and the second grounding wire 18-2 of the electrode plate 10H through the first connector 40H'. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, the third bidirectional switching switch 26-3, the fourth bidirectional switching switch 26-4 and the fifth bidirectional switching switch 26-5 on the adapter 20D are respectively and electrically connected in one-to-one correspondence with the first dual-purpose signal wire 19-1, the second dual-purpose signal wire 19-2, the third dual-purpose signal wire 19-3, the fourth dual-purpose signal wire 19-4 and the fifth dual-purpose signal wire 19-5 through the first connector 40H'. Refer to Figure 31 , the working mode of the tumor electric field treatment system formed by the electrode plate 10H, the adapter 20D and the electric field generator 30 is the same as that of the aforementioned tumor electric field treatment system 100. When all the grounding switches 25 are disconnected and the input ends 2 of all the bidirectional switching switches 26 are conducted and the acquisition ends 1 are disconnected, all the dual-purpose signal wires 19 are conducted with the AC signal wire 28, and all the electrode units 12 are connected to the AC signal; when the acquisition ends 1 of all the bidirectional switching switches 26 are conducted and the input ends 2 are disconnected, by sequentially conducting each grounding switch 25, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained in sequence.

[0171] Refer to Figure 32As shown, an adapter 20E of the seventh embodiment adapted to the electrode sheet 10J of the foregoing tenth embodiment is provided. The adapter 20E also includes: a first controller 22, multiple groups of analog-to-digital converters 23 connected to the first controller 22, multiple groups of voltage dividing resistors 24 and multiple groups of grounding switches 25 corresponding to the multiple groups of analog-to-digital converters 23 one by one, multiple groups of bidirectional switching switches 26 connected to the multiple groups of analog-to-digital converters 23 one by one, a first communication unit 27, AC signal lines 28 connected to each group of bidirectional switching switches 26 one by one, and a first power module 29 connected to the first communication unit 27, the first controller 22, and the multiple groups of analog-to-digital converters 23 at the same time. The first power module 29 provides a DC power supply VCC for each electronic component of the adapter 20E. The adapter 20E also includes multiple circuit lines (not labeled) therein. The difference between it and the foregoing adapter 20 is that: each group of grounding switches 25 of the adapter 20E reduces the setting of a fourth grounding switch 25-4, each group of bidirectional switching switches 26 reduces the setting of a fifth bidirectional switching switch 26-5 and a fourth bidirectional switching switch 26-4, and reduces the settings of the detection channels E and D corresponding to the fifth bidirectional switching switch 26-5 and the fourth bidirectional switching switch 26-4 in each group of analog-to-digital converters 23, as well as reduces the settings of the voltage dividing resistors corresponding to the fifth bidirectional switching switch 26-5 and the fourth bidirectional switching switch 26-4 in each group of voltage dividing resistors 24. For the other specific structures and working principles of the adapter 20E, please refer to the relevant specific descriptions of the foregoing adapter 20, which will not be elaborated here.

[0172] The first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 on the adapter 20E are respectively and electrically connected to the first grounding wire 18-1, the second grounding wire 18-2, and the third grounding wire 18-3 one by one through the first connector 40J'. The first bidirectional switching switch 26-1, the second bidirectional switching switch 26-2, and the third bidirectional switching switch 26-3 on the adapter 20E are respectively and electrically connected to the first dual-purpose signal wire 19-1, the second dual-purpose signal wire 19-2, and the third dual-purpose signal wire 19-3 one by one through the first connector 40J'. Refer to Figure 33 , the working mode of the tumor electric field treatment system formed by the electrode sheet 10J, the adapter 20E, and the electric field generator 30 is the same as that of the foregoing tumor electric field treatment system 100. When all the grounding switches 25 are disconnected and the input ends 2 of all the bidirectional switching switches 26 are conducting and the acquisition ends 1 are disconnected, all the dual-purpose signal wires 19 are conducting with the AC signal lines 28, and all the electrode units 12 are connected to the AC signal; when the acquisition ends 1 of all the bidirectional switching switches 26 are conducting and the input ends 2 are disconnected, by sequentially conducting each grounding switch 25, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained in sequence.

[0173] The present application also provides some temperature detection methods and AC signal application control methods, which will be described below by taking the electrode patch 10 as an example.

[0174] An embodiment of the present application provides an electrode patch temperature detection method, which is applied to the above-mentioned electrode patch 10 or the tumor electric field treatment system 100. Refer Figure 34 as shown, it includes the following steps:

[0175] Step 210: Control each bidirectional switching switch 26 electrically connected to each electrode unit 12 of the electrode patch 10 to disconnect the AC signal applied to the dielectric element 15 of each electrode unit 12 of the electrode patch 10, and at the same time connect the DC signal applied to the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 of the electrode patch 10;

[0176] Step 220: Sequentially turn on each grounding switch 25 electrically connected to the grounding terminal 14-1 of the temperature sensor 14 of each electrode unit 12 of the electrode patch 10 in time sequence to obtain the temperature detection signal of the temperature sensor 14 of each electrode unit 12 of the electrode patch 10.

[0177] Step 210 is specifically: Control the bidirectional switching switch 26 electrically connected to each electrode unit 12 of the electrode patch 10 to switch from the end electrically connected to the AC signal to the end electrically connected to the DC signal, that is, control the bidirectional switching switch 26 electrically connected to the electrode patch 10 to switch from its input terminal 2 to its acquisition terminal 1; or

[0178] Control the bidirectional switching switch 26 electrically connected to each electrode unit 12 of the electrode patch 10 to switch the dielectric element 15 of each electrode unit 12 of the electrode patch 10 from the conducting state to the disconnected state, and at the same time switch the signal terminal 14-2 of the temperature sensor 14 of each electrode unit 12 of the electrode patch 10 from the disconnected state to the conducting state.

[0179] By using the electrode patch temperature detection method of the present application, the temperatures of all electrode units of the electrode patch can be obtained quickly and accurately; and it is possible to judge whether there is a fault, whether there is an abnormality, whether the electrode patch is qualified, or whether it needs to be replaced based on the temperature detection signals of all the temperature sensors of the obtained electrode patch; it is also possible to judge whether there is overheating in each electrode unit of the electrode patch based on the temperature detection signals of all the temperature sensors of the obtained electrode patch when the temperature sensors of the electrode patch are normal, and then control the AC signal applied to the electrode patch or each electrode unit of the electrode patch; it is also possible to identify the type of the electrode patch when the temperature detection signals of the temperature sensors of the electrode patch are normal.

[0180] Refer Figure 35As shown, the embodiment of the present application further provides an alternating current signal application control method for tumor electric field therapy, which includes the above steps 210 and 220, and after step 220, it further includes:

[0181] Step 260: When it is determined that the electrode patch 10 does not need to be replaced, control or adjust the alternating current signal applied to each electrode unit 12 of the electrode patch 10 according to the temperature detection signals of the temperature sensors 14 of each electrode unit 12 of the electrode patch 10 obtained.

[0182] The control or adjustment of the alternating current signal applied to each electrode unit 12 of the electrode patch 10 in step 260 further includes:

[0183] Step 261: When the temperature detection signals of each electrode unit 12 of the electrode patch 10 obtained do not exceed the preset temperature threshold, continue to apply the alternating current signal to each electrode unit 12 of the electrode patch 10; or

[0184] Step 262: When there is a temperature detection signal exceeding the preset temperature threshold among the temperature detection signals of all electrode units 12 of the electrode patch 10 obtained, stop applying the alternating current signal to the electrode units 12 of the electrode patch 10.

[0185] The stopping of applying the alternating current signal to the electrode units 12 of the electrode patch 10 in step 262 includes stopping applying the alternating current signal to all electrode units 12 of the electrode patch 10, stopping applying the alternating current signal to the electrode units 12 of the electrode patch 10 where the temperature detection signals exceed the preset temperature threshold, and stopping applying the alternating current signal to all electrode units 12 in the column where the electrode units 12 of the electrode patch 10 with temperature detection signals exceeding the preset temperature threshold are located.

[0186] When stopping applying the alternating current signal to the electrode units 12 of the electrode patch 10 where the temperature detection signals exceed the preset temperature threshold, the electrode units 12 of the electrode patch 10 where the temperature detection signals do not exceed the preset temperature threshold continue to be applied with the alternating current signal.

[0187] When stopping applying the alternating current signal to all electrode units 12 in the column where the electrode units 12 of the electrode patch 10 with temperature detection signals exceeding the preset temperature threshold are located, the electrode units 12 of the electrode patch 10 where the temperature detection signals do not exceed the preset temperature threshold and are in different columns from the electrode units 12 with temperature detection signals exceeding the preset temperature threshold continue to be applied with the alternating current signal.

[0188] The process of continuing to apply the alternating current signal to the electrode patch 10 in step 261 is specifically:

[0189] Step 263: When the temperature detection signal is much lower than the preset temperature threshold, continue to apply an alternating current signal to each electrode unit 12 of the electrode sheet 10 by increasing the voltage or current amplitude of the alternating current signal applied to each electrode unit 12 of the electrode sheet 10 or continue to apply an alternating current signal to each electrode unit 12 of the electrode sheet 10 in a manner that keeps the voltage or current amplitude of the alternating current signal applied to each electrode unit 12 of the electrode sheet 10 unchanged; or

[0190] Step 264: When the temperature detection signal is close to the preset temperature threshold, continue to apply an alternating current signal to each electrode unit 12 of the electrode sheet 10 in a manner that keeps the voltage or current amplitude of the alternating current signal applied to each electrode unit 12 of the electrode sheet 10 unchanged or continue to apply an alternating current signal to each electrode unit 12 of the electrode sheet 10 by reducing the voltage or current amplitude of the alternating current signal applied to each electrode unit 12 of the electrode sheet 10.

[0191] See Figure 36 As shown, the present application also provides a signal control method for tumor electric field therapy for the above-mentioned electrode sheet 10, and the method includes:

[0192] Step 310: Combine and control the ground switch 25 and the bidirectional switch 26 electrically connected to the corresponding electrode sheet 10 to apply an alternating current signal to each electrode unit 12 of the electrode sheet 10 and execute Step 320;

[0193] Step 320: Combine and control the ground switch 25 and the bidirectional switch 26 electrically connected to the electrode sheet 10 to collect the temperature detection signals of each electrode unit of the electrode sheet 10 in a row and execute Step 330;

[0194] Step 330: Determine the combined control mode of the ground switch 25 and the bidirectional switch 26 electrically connected to the electrode sheet 10 according to the collected temperature detection signals and execute Step 340;

[0195] Step 340: Control the working states of each electrode unit 12 of the electrode sheet 10 according to the determined combined control mode of the ground switch 25 and the bidirectional switch 26.

[0196] The working states of each electrode unit 12 of the electrode sheet 10 described in Step 340 include: stopping applying the alternating current signal and continuing to collect the temperature detection signals and stopping collecting the temperature detection signals and continuing to apply the alternating current signal. Continuing to apply the alternating current signal includes continuing to apply the alternating current signal by increasing the voltage or current amplitude of the currently applied alternating current signal, continuing to apply the alternating current signal in a manner that keeps the voltage or current amplitude of the currently applied alternating current signal unchanged, and continuing to apply the alternating current signal by reducing the voltage or current amplitude of the currently applied alternating current signal.

[0197] The operating state of each electrode unit 12 of the electrode sheet 10 is determined by the temperature detection signal collected thereby. Each electrode unit 12 of the electrode sheet 10 is divided into different regions, and through the combination control of the grounding switches 25 and the bidirectional switching switches 26, each electrode unit 12 in each region can be cyclically switched between applying an alternating current signal and collecting a temperature detection signal.

[0198] Another electrode sheet temperature detection method for the tumor electric field therapy system 100 is provided in an embodiment of the present application. Please refer to Figure 37 as shown, this temperature detection method includes:

[0199] Step 510: Disconnect the input of the alternating current signal of the electrode sheet 10, perform combined control on a plurality of grounding switches 25 and a plurality of bidirectional switching switches 26, and obtain the temperature detection signals of the temperature sensors 14 of the electrode sheet 10 corresponding to each combination in all combinations;

[0200] Step 520: Sample and convert the temperature detection signals detected by each temperature sensor 14 in the electrode sheet 10 to obtain digital temperature signals;

[0201] Step 530: Transmit the digital temperature signals to the electric field generator 30 of the tumor electric field therapy system 100, so that the electric field generator 30 determines the temperature at the corresponding electrode unit 12 according to the digital temperature signals.

[0202] In step 510, "performing combined control on a plurality of grounding switches 25 and a plurality of bidirectional switching switches 26" specifically includes:

[0203] Step 511: Place all the bidirectional switching switches 26 at the acquisition end 1 to conduct the electrical connection between the signal ends 14-2 of the temperature sensors 14 of all electrode units 12 and the corresponding analog-to-digital converters 23;

[0204] Step 512: Sequentially and separately close one of the plurality of grounding switches 25 to sequentially collect the temperature detection signals detected by the temperature sensors 14 of the electrode units 12 in the corresponding row groups.

[0205] Sequentially and separately closing one of the plurality of grounding switches 25 in step 512 can conduct the detection channels in which the analog-to-digital converter 23 is electrically connected to all the temperature sensors 14 in the row group corresponding to the closed grounding switch 25.

[0206] Thus, the temperature detection signals of the corresponding temperature sensors 14 in each row group can be sequentially obtained, and then through the processing of the adapter 20 or the electric field generator 30, the temperatures corresponding to all the electrode units 12 on the electrode sheet 10 can be obtained; thereby making the temperature detection on the patient's body surface more comprehensive and accurate.

[0207] For the tumor electric field therapy system 100 according to the embodiments of the present application, the temperature of a single electrode unit 12 can also be detected as needed. The specific process of detecting the temperature of a certain electrode unit 12 of the electrode sheet 10 is as follows: disconnect the input of the alternating current signal, place the bidirectional switching switch 26 corresponding to the column group where the electrode unit 12 to be individually temperature-measured is located at the acquisition end 1, and place the remaining bidirectional switching switches 26 at the input end 2; at the same time, turn on and ground the grounding switch 25 corresponding to the row group where the electrode unit 12 to be individually temperature-measured is located, and disconnect all the remaining grounding switches 25. Thus, the temperature detection signal of the temperature sensor 14 in the electrode unit 12 to be individually temperature-measured can be sampled to obtain the temperature of the electrode unit 12. For example, if the electrode unit 12 to be individually temperature-measured is the electrode unit 12-1, at this time, disconnect the corresponding AC signal switch 35 of the electric field generator 30, place the first bidirectional switching switch 26-1 corresponding to the electrode unit 12-1 at the acquisition end 1, and place all the remaining other bidirectional switching switches (the second bidirectional switching switch 26-2, the second bidirectional switching switch 26-3, the third bidirectional switching switch 26-3, and the fourth bidirectional switching switch 26-4) at the input end 2; at the same time, close and ground the first grounding switch 25-1 corresponding to the electrode unit 12-1, and disconnect all the remaining grounding switches (the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4). Thus, the temperature of the electrode unit 12-1 can be detected.

[0208] The embodiments of the present application also provide another method for applying an alternating current signal for tumor electric field therapy, which is applied to the above-mentioned tumor electric field therapy system 100. Please refer to Figure 38 As shown, this method for applying an alternating current signal includes:

[0209] Step 610: Determine the area where the electrode unit 12 that needs to apply an alternating current signal is located in the electrode sheet 10;

[0210] Step 611: Combine and control a plurality of grounding switches 25 and a plurality of bidirectional switching switches 26 electrically connected to the electrode sheet 10 to apply an alternating current signal.

[0211] In step 611, "combining and controlling a plurality of grounding switches 25 and a plurality of bidirectional switching switches 26 electrically connected to the electrode sheet 10" specifically means:

[0212] Step 612: Disconnect all the grounding switches 25 electrically connected to the electrode sheet 10;

[0213] Step 613: Determine the column group where the electrode unit 12 that needs to apply an alternating current signal is located according to the area where the electrode unit 12 that needs to apply an alternating current signal is located;

[0214] Step 614: Determine the bidirectional switching switches 26 electrically connected to the electrode units 12 in the column groups where the electrode units 12 that need to be applied with AC signal are located;

[0215] In step 610: Divide every adjacent 4 electrode units 12 in the electrode sheet 10 into one area, the 4 electrode units 12 in each area correspond to one column group, and are connected to a two-way signal line 19 corresponding to the same bidirectional switching switch 26.

[0216] Step 615: Control the bidirectional switching switches 26 electrically connected to the electrode units 12 that need to be applied with AC signal to electrically connect the electrode units 12 that need to be applied with AC signal to the AC signal line 28 to apply AC signal; at the same time, control the remaining bidirectional switching switches 26 to disconnect the electrical connection between each electrode unit 12 in the area where no AC signal needs to be applied and the AC signal line 28 to stop applying AC signal.

[0217] In step 615, "electrically connect the electrode units that need to be applied with AC signal to the AC signal line 28 to apply AC signal and disconnect the electrical connection between the electrode units 12 in the area where no AC signal needs to be applied and the AC signal line 28 to stop applying AC signal" is achieved by placing the bidirectional switching switches 26 electrically connected to the electrode units 12 in the column groups corresponding to the area where AC signal needs to be applied in the electrode sheet 10 at their input terminals 2, and placing all the bidirectional switching switches 26 electrically connected to the electrode units 12 in the remaining column groups at the acquisition terminals 1.

[0218] In the adapter 20 of the tumor electric field therapy system 100 according to the embodiment of the present application, the first controller 22 or the electric field generator 30 is provided with a preset quantity threshold, a first preset temperature t1, a second preset temperature t2, and a preset temperature threshold t0, where the first preset temperature t1 is lower than the second preset temperature t2, and the second preset temperature t2 is lower than the preset temperature threshold t0.

[0219] The embodiment of the present application also provides an AC signal application method based on temperature detection signal for the above-mentioned tumor electric field therapy system 100. Please refer to Figure 39 As shown, this application method includes:

[0220] Step 710: Start the tumor electric field therapy system 100;

[0221] Step 711: Combine and control the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the corresponding electrode sheet 10 to apply AC signal to each electrode unit 12 of the electrode sheet 10;

[0222] Step 712: Combine to control the grounding switch 25 and the bidirectional switch 26 electrically connected to the electrode sheet 10 to obtain the temperatures of the respective electrode units 12 of the electrode sheet 10;

[0223] Step 713: Determine whether there is an electrode unit 12 whose temperature exceeds the first preset temperature t1. When there is no electrode unit 12 whose temperature exceeds the first preset temperature t1, execute Step 714. When there is an electrode unit 12 whose temperature exceeds the first preset temperature t1, execute Step 715;

[0224] Step 714: Continue to apply an alternating current signal to the respective electrode units 12 of the electrode sheet 10 in a manner of increasing the voltage or current amplitude of the currently applied alternating current signal and return to Step 712;

[0225] Step 715: Determine whether there is an electrode unit 12 whose temperature exceeds the second preset temperature t2; when there is no electrode unit 12 whose temperature exceeds the second preset temperature t2, execute Step 716. When there is an electrode unit 12 whose temperature exceeds the second preset temperature t2, execute Step 717;

[0226] Step 716: Continue to apply an alternating current signal to the respective electrode units 12 of the electrode sheet 10 in a manner of keeping the voltage or current amplitude of the currently applied alternating current signal unchanged and return to Step 712;

[0227] Step 717: Determine whether there is an electrode unit 12 whose temperature exceeds the preset temperature threshold t0. When there is no electrode unit 12 whose temperature exceeds the preset temperature threshold t0, execute Step 718; when there is an electrode unit whose temperature exceeds the preset temperature threshold t0, execute Step 719;

[0228] Step 718: Continue to apply an alternating current signal to all the electrode units 12 of the electrode sheet 10 in a manner of decreasing the voltage or current amplitude of the currently applied alternating current signal and return to Step 712;

[0229] Step 719: Determine the number of over-temperature regions and execute Step 720, where the over-temperature region is the region containing the electrode unit whose temperature exceeds the preset temperature threshold t0, and the non-over-temperature region is the region where the temperatures of all its electrode units do not exceed the preset temperature threshold t0;

[0230] Step 720: Determine whether the number of over-temperature regions exceeds the preset number threshold. When the number of over-temperature regions exceeds the preset number threshold, execute Step 721. When the number of over-temperature regions does not exceed the preset number threshold, execute Step 724;

[0231] Step 721: Stop applying the alternating current signal to the respective electrode units 12 of the electrode sheet 10 and execute Step 722;

[0232] Step 722: Combine to control the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to obtain the temperatures of the respective electrode units 12 of the electrode sheet 10 and execute Step 723;

[0233] Step 723: Determine whether there is an electrode unit 12 whose temperature exceeds the first preset temperature t1. When there is no electrode unit 12 on the electrode sheet 10 whose temperature exceeds the first preset temperature t1, return to Step 711. When there is an electrode unit 12 on the electrode sheet 10 whose temperature exceeds the first preset temperature t1, return to Step 722;

[0234] Step 724: Distinguish the over-temperature area and the non-over-temperature area according to whether there is an electrode unit 12 whose temperature exceeds the preset temperature threshold t0. When the area is the over-temperature area, execute Step 725. When the area is the non-over-temperature area, execute Step 726;

[0235] Step 725: Stop applying the alternating current signal to the respective electrode units 12 in the over-temperature area and execute Step 731;

[0236] Step 726: Determine whether the temperatures of the respective electrode units 12 in the non-over-temperature area do not exceed the first preset temperature t1. When the temperatures of the respective electrode units 12 in the non-over-temperature area do not exceed the first preset temperature t1, execute Step 727. When there is a temperature that exceeds the first preset temperature t1 among the temperatures of the respective electrode units 12 in the non-over-temperature area, execute Step 728;

[0237] Step 727: Continue to apply the alternating current signal to the respective electrode units 12 in the non-over-temperature area of the electrode sheet 10 by increasing the voltage or current amplitude of the currently applied alternating current signal and execute Step 731;

[0238] Step 728: Determine whether the temperatures of the respective electrode units 12 in the non-over-temperature area do not exceed the second preset temperature t2. When the temperatures of the respective electrode units 12 in the non-over-temperature area do not exceed the second preset temperature t2, execute Step 729. When there is a temperature that exceeds the second preset temperature t2 among the temperatures of the respective electrode units 12 in the non-over-temperature area, execute Step 730;

[0239] Step 729: Continue to apply the alternating current signal to the respective electrode units 12 in the non-over-temperature area of the electrode sheet 10 by keeping the voltage or current amplitude of the currently applied alternating current signal unchanged and execute Step 731;

[0240] Step 730: Continue to apply the alternating current signal to the respective electrode units 12 in the non-over-temperature area of the electrode sheet 10 by decreasing the voltage or current amplitude of the currently applied alternating current signal and execute Step 731;

[0241] Step 731: Combine to control the grounding switch 25 and the bidirectional switch 26 electrically connected to the electrode sheet 10 to reacquire the temperatures of the respective electrode units 12 of the electrode sheet 10 and select to execute Step 732 or Step 734. The temperatures of the respective electrode units 12 of the electrode sheet 10 include the temperatures of the respective electrode units 12 in the over-temperature area and the temperatures of the respective electrode units 12 in the non-over-temperature area;

[0242] Step 732: Determine whether the temperatures of the respective electrode units 12 in the over-temperature area all do not exceed the first preset temperature t1. When the temperatures of the respective electrode units 12 in the over-temperature area all do not exceed the first preset temperature t1, execute Step 733. When there is a temperature exceeding the first preset temperature t1 among the temperatures of the respective electrode units 12 in the over-temperature area, return to Step 731;

[0243] Step 733: Re-determine this area as a non-over-temperature area and execute Step 734;

[0244] Step 734: Determine whether the temperatures of the respective electrode units 12 in the acquired non-over-temperature area all do not exceed the first preset temperature t1. When the temperatures of the respective electrode units 12 in the non-over-temperature area all do not exceed the first preset temperature t1, execute Step 735. When there is a temperature exceeding the first preset temperature t1 among the temperatures of the respective electrode units 12 in the non-over-temperature area, execute Step 736;

[0245] Step 735: Continue to apply an alternating current signal to the respective electrode units 12 in the non-over-temperature area in a manner of increasing the voltage or current amplitude of the currently applied alternating current signal and return to Step 712;

[0246] Step 736: Determine whether the temperatures of the respective electrode units 12 in the acquired non-over-temperature area all do not exceed the second preset temperature t2. When the temperatures of the respective electrode units 12 in the non-over-temperature area all do not exceed the second preset temperature t2, execute Step 737. When there is a temperature exceeding the second preset temperature t2 among the temperatures of the respective electrode units 12 in the non-over-temperature area, execute Step 738;

[0247] Step 737: Continue to apply an alternating current signal to the respective electrode units 12 in the non-over-temperature area in a manner of keeping the voltage or current amplitude of the currently applied alternating current signal unchanged and return to Step 712;

[0248] Step 738: Determine whether the temperatures of the respective electrode units 12 in the acquired non-over-temperature area all do not exceed the preset temperature threshold t0. When the temperatures of the respective electrode units 12 in the non-over-temperature area all do not exceed the preset temperature threshold t0, execute Step 739. When there is a temperature exceeding the preset temperature threshold t0 among the temperatures of the respective electrode units 12 in the non-over-temperature area, return to Step 719;

[0249] Step 739: Continue to apply an alternating current signal to each electrode unit 12 of the non-overtemperature region in a manner that reduces the voltage or current amplitude of the currently applied alternating current signal, and return to Step 712.

[0250] Among them, as Figure 39 shown, the process of the combined control in Step 711 of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the corresponding electrode plate 10 to apply an alternating current signal to each electrode unit 12 of the electrode plate is specifically as follows:

[0251] Disconnect all the grounding switches 25 electrically connected to the corresponding electrode plate 10, and at the same time switch all the bidirectional switching switches 26 electrically connected to the corresponding electrode plate 10 to the end for applying an alternating current signal to each electrode unit 12; or

[0252] Disconnect all the grounding switches 25 electrically connected to the corresponding electrode plate 10, and at the same time switch all the bidirectional switching switches 26 electrically connected to the corresponding electrode plate 10 to the end for electrically connecting each electrode unit 12 to the AC signal line 28; or

[0253] Disconnect all the grounding switches 25 electrically connected to the corresponding electrode plate 10, and at the same time switch all the bidirectional switching switches 26 electrically connected to the corresponding electrode plate 10 to their respective input terminals 2.

[0254] The process of obtaining the temperature of each electrode unit 12 of the electrode plate 10 in Step 712, Step 722, and Step 731 is specifically as follows:

[0255] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch all from the end for applying an alternating current signal to each electrode unit 12 to the end for temperature acquisition of each electrode unit 12, and sequentially close the grounding switches 25 electrically connected to the electrode units 12 of the electrode plate 10 at different times to obtain the temperature of each electrode unit 12 of the electrode plate 10; or

[0256] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch all from the input terminal 2 for applying an alternating current signal to each electrode unit 12 to its acquisition terminal 1, and sequentially close the grounding switches 25 electrically connected to the electrode units 12 of the electrode plate 10 at different times to obtain the temperature of each electrode unit 12 of the electrode plate 10; or

[0257] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch the electrode plate 10 from the electrical connection of each electrode unit 12 to the AC signal line 28 to the electrical connection of each electrode unit 12 to the corresponding analog-to-digital converter 23, and sequentially close the grounding switches 25 electrically connected to each electrode unit 12 of the electrode plate 10 at different times to obtain the temperature of each electrode unit 12 of the electrode plate 10; or

[0258] Control the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to cause each electrode unit 12 of the electrode sheet 10 to switch from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal, and sequentially close the grounding switches 25 electrically connected to the respective electrode units 12 of the electrode sheet 10 at different times to obtain the temperatures of the respective electrode units 12 of the electrode sheet 10.

[0259] The first preset temperature in step 713, step 723, step 726, step 732, and step 734 is 40°C - 40.3°C, preferably 40.2°C. The second preset temperature in step 715, step 728, and step 736 is 40.4°C to 40.6°C, preferably 40.5°C; the preset temperature threshold in step 717 and step 738 is 41°C to 41.5°C, preferably 41°C; the preset quantity threshold in step 720 is preferably 2.

[0260] The process of continuing to apply the alternating current signal in step 714, step 716, step 718, step 727, step 729, step 730, step 735, step 737, and step 739 is specifically as follows:

[0261] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue to apply the alternating current signal, and at the same time control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to continue to apply the alternating current signal to conduct the alternating current signal transmission path electrically connected to the electrode unit 12 that needs to continue to apply the alternating current signal, so as to continue to apply the alternating current signal to the electrode unit 12 that needs to continue to apply the alternating current signal; or

[0262] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue to apply the alternating current signal, and at the same time control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to continue to apply the alternating current signal to switch from its respective acquisition end 1 to its respective input end 2, so as to continue to apply the alternating current signal to the electrode unit 12 that needs to continue to apply the alternating current signal; or

[0263] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue to apply the alternating current signal, and at the same time control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to continue to apply the alternating current signal to electrically connect its respective input ends 2 to the AC signal line 28, so as to continue to apply the alternating current signal to the electrode unit 12 that needs to continue to apply the alternating current signal; or

[0264] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue to apply the alternating current signal, and at the same time control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to continue to apply the alternating current signal to close its respective input ends 2 and disconnect its respective acquisition ends 1, so as to continue to apply the alternating current signal to the electrode unit 12 that needs to continue to apply the alternating current signal; or

[0265] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 to which an alternating current signal needs to be continuously applied, and at the same time control the bidirectional switch 26 electrically connected to the electrode unit 12 to which an alternating current signal needs to be continuously applied to switch the electrode unit 12 to which an alternating current signal needs to be continuously applied from transmitting a temperature detection signal to applying an alternating current signal.

[0266] In steps 714, 727, and 735, increasing the voltage or current amplitude of the currently applied alternating current signal specifically means boosting the voltage of the currently applied alternating current signal in a manner of increasing the direct current voltage amplitude by 0.03V per second.

[0267] In steps 718, 730, and 739, continuing to apply an alternating current signal in a manner of reducing the voltage or current amplitude of the currently applied alternating current signal specifically means continuing to apply an alternating current signal in a manner of being 5V less than the voltage amplitude of the currently applied alternating current signal and lasting for 3 minutes.

[0268] The process of stopping applying an alternating current signal to each electrode unit 12 of the electrode plate 10 in step 721 is specifically as follows:

[0269] Control the bidirectional switch 26 electrically connected to the electrode plate 10 to disconnect the electrical connection between each electrode unit 12 of the electrode plate 10 and the AC signal line 28; or

[0270] Control the bidirectional switch 26 electrically connected to the electrode plate 10 to switch all from the end where each electrode unit 12 applies an alternating current signal to the end where each electrode unit 12 performs temperature acquisition; or

[0271] Control the bidirectional switch 26 electrically connected to the electrode plate 10 to switch all from the input terminal 2 where each electrode unit 12 applies an alternating current signal to the acquisition terminal 1; or

[0272] Control the bidirectional switch 26 electrically connected to the electrode plate 10 to switch the electrode plate 10 from the electrical connection between each electrode unit 12 and the AC signal line 28 to the electrical connection between each electrode unit 12 and the corresponding analog-to-digital converter 23; or

[0273] Control the bidirectional switch 26 electrically connected to the electrode plate 10 to switch each electrode unit 12 of the electrode plate 10 from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0274] The process of stopping applying an alternating current signal to each electrode unit 12 in the over-temperature area in step 725 is specifically as follows:

[0275] Control the bidirectional switch 26 electrically connected to each electrode unit 12 in the over-temperature area to disconnect the electrical connection between each electrode unit 12 in the over-temperature area and the AC signal line 28; or

[0276] Control the bidirectional switch 26 electrically connected to each electrode unit 12 in the over-temperature area to switch all from the end that applies the AC signal to each electrode unit 12 in the over-temperature area to the end that performs temperature acquisition on each electrode unit 12 in the over-temperature area; or

[0277] Control the bidirectional switch 26 electrically connected to each electrode unit 12 in the over-temperature area to switch all from the input terminal 2 that applies the AC signal to each electrode unit 12 in the over-temperature area to the acquisition terminal 1; or

[0278] Control the bidirectional switch 26 electrically connected to each electrode unit 12 in the over-temperature area to cause each electrode unit 12 in the over-temperature area to switch from being electrically connected to the AC signal line 28 to being electrically connected to the corresponding analog-to-digital converter 23; or

[0279] Control the bidirectional switch 26 electrically connected to each electrode unit 12 in the over-temperature area to cause each electrode unit 12 in the over-temperature area to switch from transmitting the AC signal to transmitting the DC signal or the temperature detection signal.

[0280] In the above application method, the tumor electric field therapy system 100 includes at least two pairs of electrode plates 10 to alternately apply alternating electric fields in different directions, and each electrode plate 10 can alternately switch between applying the AC signal and transmitting the temperature detection signal. The time periods for the electrode units 12 of the same electrode plate 10 to apply the AC signal and to perform temperature acquisition by applying the DC signal are staggered and do not overlap.

[0281] In the adapter 20 of the tumor electric field therapy system 100 according to the embodiment of the present application, or in the electric field generator 30, there is also a third preset temperature t3, and the third preset temperature t3 is higher than the second preset temperature t2 but still lower than the preset temperature threshold t0. The third preset temperature t3 is closer to the preset temperature threshold t0 than the second preset temperature t2. The embodiment of the present application also provides an AC signal control method based on the temperature detection signal for the above-mentioned tumor electric field therapy system. Refer Figure 40 As shown, this AC signal control method includes:

[0282] Step 810: Start the tumor electric field therapy system 100;

[0283] Step 811: Combine to control the grounding switch 25 and the bidirectional switch 26 electrically connected to the corresponding electrode plate 10 to apply the AC signal to each electrode unit 12 of the electrode plate 10;

[0284] Step 812: Combine to control the grounding switch 25 and the bidirectional switch 26 electrically connected to the electrode plate 10 to obtain the temperature of each electrode unit 12 of the electrode plate 10;

[0285] Step 813: Determine whether there is an electrode unit 12 with a temperature exceeding the first preset temperature t1. When there is no electrode unit 12 with a temperature exceeding the first preset temperature t1, execute Step 814; when there is an electrode unit 12 with a temperature exceeding the first preset temperature t1, execute Step 815;

[0286] Step 814: Continue to apply an alternating current signal to each electrode unit 12 of the electrode sheet 10 by increasing the voltage or current amplitude of the currently applied alternating current signal and return to Step 812;

[0287] Step 815: Determine whether there is an electrode unit 12 with a temperature exceeding the second preset temperature t2; when there is no electrode unit 12 with a temperature exceeding the second preset temperature t2, execute Step 816; when there is an electrode unit 12 with a temperature exceeding the second preset temperature t2, execute Step 817;

[0288] Step 816: Continue to apply an alternating current signal to each electrode unit 12 of the electrode sheet 10 while keeping the voltage or current amplitude of the currently applied alternating current signal unchanged and return to Step 812;

[0289] Step 817: Determine whether there is an electrode unit 12 with a temperature exceeding the third preset temperature t3. When there is no electrode unit 12 with a temperature exceeding the third preset temperature t3, execute Step 818; when there is an electrode unit with a temperature exceeding the third preset temperature t3, execute Step 819;

[0290] Step 818: Continue to apply an alternating current signal to all electrode units 12 of the electrode sheet 10 by reducing the voltage or current amplitude of the currently applied alternating current signal and return to Step 812;

[0291] Step 819: Determine whether there is an electrode unit 12 with a temperature exceeding the preset temperature threshold t0. When there is no electrode unit 12 with a temperature exceeding the preset temperature threshold t0, execute Step 820; when there is an electrode unit with a temperature exceeding the preset temperature threshold t0, execute Step 821;

[0292] Step 820: Continue to apply an alternating current signal to all electrode units 12 of the electrode sheet 10 by reducing the voltage or current amplitude of the currently applied alternating current signal and return to Step 812;

[0293] Step 821: Determine the number of over-temperature regions and execute Step 822, where the over-temperature region is the region containing the electrode unit with a temperature exceeding the preset temperature threshold t0, and the non-over-temperature region is the region where the temperatures of all its electrode units do not exceed the preset temperature threshold t0;

[0294] Step 822: Determine whether the number of over-temperature regions exceeds a preset number threshold. When the number of over-temperature regions exceeds the preset number threshold, execute Step 823. When the number of over-temperature regions does not exceed the preset number threshold, execute Step 826;

[0295] Step 823: Stop applying the alternating current signal to each electrode unit 12 of the electrode sheet 10 and execute Step 824;

[0296] Step 824: Combine and control the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the electrode sheet 10 to obtain the temperature of each electrode unit 12 of the electrode sheet 10 and execute Step 825;

[0297] Step 825: Determine whether there is an electrode unit 12 whose temperature exceeds the first preset temperature t1. When there is no electrode unit 12 on the electrode sheet 10 whose temperature exceeds the first preset temperature t1, return to Step 811. When there is an electrode unit 12 on the electrode sheet 10 whose temperature exceeds the first preset temperature t1, return to Step 824;

[0298] Step 826: Distinguish the over-temperature regions and non-over-temperature regions according to whether there are electrode units 12 whose temperature exceeds the preset temperature threshold t0. When the region is an over-temperature region, execute Step 827. When the region is a non-over-temperature region, execute Step 828;

[0299] Step 827: Stop applying the alternating current signal to each electrode unit 12 in the over-temperature region and execute Step 835;

[0300] Step 828: Determine whether the temperature of each electrode unit 12 in the non-over-temperature region does not exceed the first preset temperature t1. When the temperature of each electrode unit 12 in the non-over-temperature region does not exceed the first preset temperature t1, execute Step 829. When there is a temperature exceeding the first preset temperature t1 among the temperatures of each electrode unit 12 in the non-over-temperature region, execute Step 830;

[0301] Step 829: Continue to apply the alternating current signal to each electrode unit 12 in the non-over-temperature region of the electrode sheet 10 by increasing the voltage or current amplitude of the currently applied alternating current signal and execute Step 835;

[0302] Step 830: Determine whether the temperature of each electrode unit 12 in the non-over-temperature region does not exceed the second preset temperature t2. When the temperature of each electrode unit 12 in the non-over-temperature region does not exceed the second preset temperature t2, execute Step 831. When there is a temperature exceeding the second preset temperature t2 among the temperatures of each electrode unit 12 in the non-over-temperature region, execute Step 832;

[0303] Step 831: Continue to apply an alternating current signal to each electrode unit 12 in the non-overheating area of the electrode sheet 10 in a manner that keeps the voltage or current amplitude of the currently applied alternating current signal unchanged, and execute Step 835;

[0304] Step 832: Determine whether there is an electrode unit 12 in the non-overheating area whose temperature exceeds the third preset temperature t3. When the temperatures of all electrode units 12 in the non-overheating area do not exceed the third preset temperature t3, execute Step 833. When there is a temperature exceeding the third preset temperature t3 among the temperatures of all electrode units 12 in the non-overheating area, execute Step 834;

[0305] Step 833: Continue to apply an alternating current signal to each electrode unit 12 in the non-overheating area of the electrode sheet 10 in a manner that reduces the voltage or current amplitude of the currently applied alternating current signal, and execute Step 835;

[0306] Step 834: Continue to apply an alternating current signal to each electrode unit 12 in the non-overheating area of the electrode sheet 10 in a manner that further reduces the voltage or current amplitude of the currently applied alternating current signal, and execute Step 835;

[0307] Step 835: Combine the control of the grounding switch 25 and the bidirectional switch 26 electrically connected to the electrode sheet 10 to re-obtain the temperatures of each electrode unit 12 of the electrode sheet 10, and select to execute Step 836 or Step 838. The temperatures of each electrode unit 12 of the electrode sheet 10 include the temperatures of each electrode unit 12 in the overheating area and the temperatures of each electrode unit 12 in the non-overheating area;

[0308] Step 836: Determine whether the temperatures of all electrode units 12 in the overheating area do not exceed the first preset temperature t1. When the temperatures of all electrode units 12 in the overheating area do not exceed the first preset temperature t1, execute Step 837. When there is a temperature exceeding the first preset temperature t1 among the temperatures of all electrode units 12 in the overheating area, return to Step 835;

[0309] Step 837: Re-determine this area as a non-overheating area and execute Step 838;

[0310] Step 838: Determine whether the temperatures of all electrode units 12 in the obtained non-overheating area do not exceed the first preset temperature t1. When the temperatures of all electrode units 12 in the non-overheating area do not exceed the first preset temperature t1, execute Step 839. When there is a temperature exceeding the first preset temperature t1 among the temperatures of all electrode units 12 in the non-overheating area, execute Step 840;

[0311] Step 839: Continue to apply an alternating current signal to each electrode unit 12 in the non-overtemperature region in a manner of increasing the voltage or current amplitude of the currently applied alternating current signal, and return to Step 812;

[0312] Step 840: Determine whether the temperatures of all electrode units 12 in the obtained non-overtemperature region do not exceed the second preset temperature t2. When the temperatures of all electrode units 12 in the non-overtemperature region do not exceed the second preset temperature t2, execute Step 841. When there is a temperature exceeding the second preset temperature t2 among the temperatures of the electrode units 12 in the non-overtemperature region, execute Step 842;

[0313] Step 841: Continue to apply an alternating current signal to each electrode unit 12 in the non-overtemperature region in a manner of keeping the voltage or current amplitude of the currently applied alternating current signal unchanged, and return to Step 812;

[0314] Step 842: Determine whether the temperatures of all electrode units 12 in the obtained non-overtemperature region do not exceed the third preset temperature t3. When the temperatures of all electrode units 12 in the non-overtemperature region do not exceed the third preset temperature t3, execute Step 843. When there is a temperature exceeding the third preset temperature t3 among the temperatures of the electrode units 12 in the non-overtemperature region, execute Step 844;

[0315] Step 843: Continue to apply an alternating current signal to each electrode unit 12 in the non-overtemperature region in a manner of decreasing the voltage or current amplitude of the currently applied alternating current signal, and return to Step 812;

[0316] Step 844: Determine whether the temperatures of all electrode units 12 in the obtained non-overtemperature region do not exceed the preset temperature threshold t0. When the temperatures of all electrode units 12 in the non-overtemperature region do not exceed the preset temperature threshold t0, execute Step 845. When there is a temperature exceeding the preset temperature threshold t0 among the temperatures of the electrode units 12 in the non-overtemperature region, return to Step 821;

[0317] Step 845: Continue to apply an alternating current signal to each electrode unit 12 in the non-overtemperature region in a manner of further decreasing the voltage or current amplitude of the currently applied alternating current signal, and return to Step 812.

[0318] Among them, the process of applying an alternating current signal to each electrode unit 12 of the corresponding electrode plate 10 by the combined control of the grounding switch 25 and the bidirectional switching switch 26 electrically connected to the corresponding electrode plate 10 in Step 811 is specifically as follows:

[0319] Disconnect all grounding switches 25 that are electrically connected to the corresponding electrode plate 10, and at the same time switch all bidirectional switching switches 26 that are electrically connected to the corresponding electrode plate 10 to the end that applies an alternating current signal to each electrode unit 12; or

[0320] Disconnect all grounding switches 25 that are electrically connected to the corresponding electrode sheet 10, and simultaneously switch all two-way switching switches 26 that are electrically connected to the corresponding electrode sheet 10 to the end that electrically connects each electrode unit 12 to the AC signal line 28; or

[0321] Disconnect all grounding switches 25 that are electrically connected to the corresponding electrode sheet 10, and simultaneously switch all two-way switching switches 26 that are electrically connected to the corresponding electrode sheet 10 to their respective input terminals 2.

[0322] The process of obtaining the temperature of each electrode unit 12 of the electrode sheet 10 in step 812, step 824, and step 835 is specifically as follows:

[0323] Control the two-way switching switch 26 that is electrically connected to the electrode sheet 10 to switch from the end that applies an AC signal to each electrode unit 12 to the end that performs temperature acquisition on each electrode unit 12, and sequentially close the grounding switches 25 that are electrically connected to the electrode units 12 of the electrode sheet 10 at different times to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or

[0324] Control the two-way switching switch 26 that is electrically connected to the electrode sheet 10 to switch from the input terminal 2 that applies an AC signal to each electrode unit 12 to its acquisition terminal 1, and sequentially close the grounding switches 25 that are electrically connected to the electrode units 12 of the electrode sheet 10 at different times to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or

[0325] Control the two-way switching switch 26 that is electrically connected to the electrode sheet 10 to switch the electrode sheet 10 from the electrical connection of each electrode unit 12 to the AC signal line 28 to the electrical connection of each electrode unit 12 to the corresponding analog-to-digital converter 23, and sequentially close the grounding switches 25 that are electrically connected to the electrode units 12 of the electrode sheet 10 at different times to obtain the temperature of each electrode unit 12 of the electrode sheet 10; or

[0326] Control the two-way switching switch 26 that is electrically connected to the electrode sheet 10 to switch each electrode unit 12 of the electrode sheet 10 from transmitting an AC signal to transmitting a DC signal or a temperature detection signal, and sequentially close the grounding switches 25 that are electrically connected to the electrode units 12 of the electrode sheet 10 at different times to obtain the temperature of each electrode unit 12 of the electrode sheet 10.

[0327] The first preset temperature in Step 813, Step 825, Step 828, Step 836, and Step 838 is 40°C - 40.3°C, preferably 40.2°C. The second preset temperature in Step 815, Step 830, and Step 840 is 40.4°C to 40.6°C, preferably 40.5°C; the third preset temperature in Step 817, Step 832, and Step 842 is 40.7°C to 40.9°C, preferably 40.8°C; the preset temperature threshold in Step 819 and Step 844 is 41°C to 41.5°C, preferably 41°C; the preset quantity threshold in Step 822 is preferably 2.

[0328] The process of continuously applying an alternating current signal in Step 814, Step 816, Step 818, Step 820, Step 829, Step 831, Step 833, Step 834, Step 839, Step 841, Step 843, and Step 845 is specifically as follows:

[0329] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue to be applied with an alternating current signal, and at the same time control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to continue to be applied with an alternating current signal to conduct the alternating current signal transmission path electrically connected to the electrode unit 12 that needs to continue to be applied with an alternating current signal, so as to continue to apply an alternating current signal to the electrode unit 12 that needs to continue to be applied with an alternating current signal; or

[0330] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue to be applied with an alternating current signal, and at the same time control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to continue to be applied with an alternating current signal to switch from its respective acquisition end 1 to its respective input end 2, so as to continue to apply an alternating current signal to the electrode unit 12 that needs to continue to be applied with an alternating current signal; or

[0331] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue to be applied with an alternating current signal, and at the same time control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to continue to be applied with an alternating current signal so that its respective input ends 2 are electrically connected to the AC signal line 28, so as to continue to apply an alternating current signal to the electrode unit 12 that needs to continue to be applied with an alternating current signal; or

[0332] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue to be applied with an alternating current signal, and at the same time control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to continue to be applied with an alternating current signal to close its respective input ends 2 and disconnect the acquisition ends 1, so as to continue to apply an alternating current signal to the electrode unit 12 that needs to continue to be applied with an alternating current signal; or

[0333] Disconnect the grounding switch 25 electrically connected to the electrode unit 12 that needs to continue to be applied with an alternating current signal, and at the same time control the bidirectional switching switch 26 electrically connected to the electrode unit 12 that needs to continue to be applied with an alternating current signal to switch the electrode unit 12 that needs to continue to be applied with an alternating current signal from transmitting a temperature detection signal to applying an alternating current signal.

[0334] The manner of continuing to apply the alternating current signal by increasing the voltage or current amplitude of the currently applied alternating current signal in step 814, step 829, and step 839 is specifically to boost the currently applied alternating current signal by increasing the direct current voltage amplitude increment of 0.03V per second and then continue to apply the alternating current signal.

[0335] The manner of continuing to apply the alternating current signal by reducing the voltage or current amplitude of the currently applied alternating current signal in step 818, step 820, step 833, step 834, step 843, and step 845 is specifically to continue to apply the alternating current signal in a manner that the voltage amplitude is 5V less than the currently applied alternating current signal and lasts for 3 minutes.

[0336] The process of stopping applying the alternating current signal to each electrode unit 12 of the electrode plate 10 in step 823 is specifically as follows:

[0337] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to disconnect the electrical connection between each electrode unit 12 of the electrode plate 10 and the AC signal line 28; or

[0338] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch all ends that make each electrode unit 12 apply an alternating current signal to the ends that make each electrode unit 12 perform temperature acquisition; or

[0339] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch the input terminal 2 that makes each electrode unit 12 apply an alternating current signal to the acquisition terminal 1; or

[0340] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch the electrode plate 10 from the electrical connection between each electrode unit 12 and the AC signal line 28 to the electrical connection between each electrode unit 12 and the corresponding analog-to-digital converter 23; or

[0341] Control the bidirectional switching switch 26 electrically connected to the electrode plate 10 to switch each electrode unit 12 of the electrode plate 10 from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0342] The process of stopping applying the alternating current signal to each electrode unit 12 in the over-temperature area in step 827 is specifically as follows:

[0343] Control the bidirectional switch 26 electrically connected to each electrode unit 12 in the over-temperature area to disconnect the electrical connection between each electrode unit 12 in the over-temperature area and the AC signal line 28; or

[0344] Control the bidirectional switch 26 electrically connected to each electrode unit 12 in the over-temperature area to switch all from the end that applies the AC signal to each electrode unit 12 in the over-temperature area to the end that performs temperature acquisition on each electrode unit 12 in the over-temperature area; or

[0345] Control the bidirectional switch 26 electrically connected to each electrode unit 12 in the over-temperature area to switch all from the input terminal 2 that applies the AC signal to each electrode unit 12 in the over-temperature area to its acquisition terminal 1; or

[0346] Control the bidirectional switch 26 electrically connected to each electrode unit 12 in the over-temperature area to cause each electrode unit 12 in the over-temperature area to switch from its electrical connection with the AC signal line 28 to its electrical connection with the corresponding analog-to-digital converter 23; or

[0347] Control the bidirectional switch 26 electrically connected to each electrode unit 12 in the over-temperature area to cause each electrode unit 12 in the over-temperature area to switch from transmitting the AC signal to transmitting the DC signal or the temperature detection signal.

[0348] When the tumor electric field treatment system 100 is in the standby state before starting to work, no AC signal is applied to the electrode unit 12. The first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls the bidirectional switch 26 to switch to the acquisition terminal 1, and the grounding switches 25 are sequentially conducted respectively. The analog-to-digital converter 23 sequentially receives the temperature detection signals of the temperature sensors 14 corresponding to each row of electrode units 12.

[0349] When the first grounding switch 25-1 is conducted, the other grounding switches 25 are all disconnected, and when the bidirectional switches 26 are all placed at the acquisition terminal 1, the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12;

[0350] When the second grounding switch 25-2 is conducted, the other grounding switches 25 are all disconnected, and when the bidirectional switches 26 are all placed at the acquisition terminal 1, the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12;

[0351] When the third grounding switch 25-3 is conducted, the other grounding switches 25 are all disconnected, and when the bidirectional switches 26 are all placed at the acquisition terminal 1, the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12;

[0352] When the fourth grounding switch 25-4 is turned on, all other grounding switches 25 are turned off, and all the bidirectional switching switches 26 are placed at the acquisition end 1, the analog-to-digital converter 23 receives the temperature detection signal of the temperature sensor 14 corresponding to the electrode unit 12.

[0353] The first controller 22 receives the temperature detection signals of the temperature sensors 14 corresponding to the respective electrode units 12 through the analog-to-digital converter 23, and transmits them to the AC signal generator 34 of the electric field generator 30 through the first communication unit 27 and the second communication unit 33, and then controls or adjusts the alternating current signals applied to the respective electrode units 12 through the second controller 32.

[0354] When the above methods are applied to the electrode plates (10D, 10E, 10F, 10G, and 10J) of other embodiments, since there are grounding switches 25 in an idle off state and / or bidirectional switching switches 26 in an idle off state on the adapter 20 that are not electrically connected to the corresponding electrode plates (10D, 10E, 10F, 10G, and 10J), the corresponding grounding switches 25 in an idle off state and / or bidirectional switching switches 26 in an idle off state do not need to be subjected to relevant control.

[0355] Although each operation is depicted in the drawings as occurring in a specific order, this should not be construed as requiring that the operations must occur in the specific order shown or in a sequential order, nor should it be construed as requiring that all of the illustrated operations must be performed to obtain the desired result.

[0356] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application and are not intended to limit them; although the present application has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that they can still modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements for some or all of the technical features; and these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present application, and they should all be covered within the scope of the claims and the description of the present application. In particular, as long as there is no structural conflict, the various technical features mentioned in each embodiment can be combined in any manner. The present application is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.

Claims

1. A method for detecting electrode temperature, characterized in that: An electrode sheet used for applying an alternating electric signal to a tumor site or tumor tissue culture to inhibit tumor growth or inhibit cancer cell mitosis, the electrode sheet comprising: a plurality of dielectric elements to which an alternating current signal is applied; A plurality of temperature sensors for detecting the temperature at corresponding parts of the corresponding dielectric elements, wherein the plurality of temperature sensors are respectively arranged in one-to-one correspondence with the plurality of dielectric elements and are configured into a plurality of row groups and a plurality of column groups in terms of circuit connection; A plurality of grounding wires, corresponding to the plurality of row groups respectively, each of the grounding wires being configured to short-circuit the grounding end of each temperature sensor in the corresponding row group to ground; as well as Multiple dual-purpose signal lines, corresponding to the plurality of column groups respectively, each of the dual-purpose signal lines is simultaneously connected to the signal end of each temperature sensor in the corresponding column group and each dielectric element in the corresponding column group and switches between transmitting a direct current signal to each temperature sensor in the corresponding column group to collect a temperature detection signal and transmitting an alternating current signal to each dielectric element in the corresponding column group to perform tumor treatment; The method comprises: transmitting a direct current signal to the multiplexed signal line of the electrode sheet; and Conducting each grounding line of the electrode sheet in sequence and in time division to collect the temperature detection signals detected by each temperature sensor in each row group of the corresponding electrode sheet in row; or Transmitting a direct current signal to any dual-purpose signal line in the electrode sheet; and Each grounding line of the electrode sheet is turned on in sequence and in a time-sharing manner to collect temperature detection signals detected by each temperature sensor in the corresponding column group one by one.

2. The method according to claim 1, characterized in that The transmission of the direct current signal to the multiple or any one of the dual-purpose signal lines of the electrode sheet is performed after the application of the alternating current signal to the electrode sheet is stopped.

3. The method according to claim 2, characterized in that The stopping of applying the alternating current signal to the electrode sheet is achieved by stopping transmitting the alternating current signal to each of the dual-purpose signal lines.

4. The method according to claim 1, characterized in that: Each of the grounding lines is disconnected when the dual-purpose signal line transmits an alternating current signal to each dielectric element in the corresponding column group for tumor treatment.

5. The method according to claim 1, characterized in that The multiple grounding wires are closed in sequence when the dual-purpose signal wire transmits a DC signal to each temperature sensor in the corresponding column group to collect temperature detection signals, and only one grounding wire is turned on at the same time, while the other grounding wires are disconnected.

6. The method according to claim 1, characterized in that Also includes: Converting the collected temperature detection signals to obtain digital temperature signals; as well as The temperature at the corresponding position of each dielectric element is determined based on each digital temperature signal.

7. The method according to any one of claims 1 to 3, characterized in that Each of the grounding wires is electrically connected to a grounding switch, and each of the dual-purpose signal wires is electrically connected to a bidirectional switching switch. The temperature detection signals detected by each of the temperature sensors are collected by combining and controlling each of the grounding switches and each of the bidirectional switching switches.

8. The method according to claim 7, characterized in that The switching of the dual-purpose signal line between transmitting a direct current signal to each temperature sensor in the corresponding column group to collect a temperature detection signal and transmitting an alternating current signal to each dielectric element in the corresponding column group for tumor treatment is achieved by combining and controlling the corresponding bidirectional switching switch and each of the grounding switches.

9. The method according to claim 7, characterized in that: The bidirectional switching switch has a fixed end electrically connected to the corresponding dual-purpose signal line, a collection end conductively connected to the fixed end to transmit a DC signal, and an input end conductively connected to the fixed end to transmit an AC signal. When the dual-purpose signal line electrically connected to the bidirectional switching switch transmits an AC signal, the fixed end of the bidirectional switching switch is conductively connected to the input end, or when the dual-purpose signal line electrically connected to the bidirectional switching switch transmits a DC signal, the fixed end of the bidirectional switching switch is conductively connected to the collection end.

10. A method for applying an alternating current signal for electric field therapy of tumors, characterized in that: include: The temperature detection signal obtained by the method according to any one of claims 1 to 9 controls or adjusts the alternating current signal applied to each dielectric element of the electrode sheet.

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