Fragrant medicine composition for enhancing disease resistance as well as preparation method and application of fragrant medicine composition

Abstract

The invention discloses a fragrant medicine composition for enhancing disease resistance as well as a preparation method and application thereof, and the fragrant medicine composition for enhancing disease resistance is prepared from the following raw materials in parts by weight: 4-6 parts of sandalwood, 8-12 parts of ligusticum, 16-24 parts of radix angelicae, 8-12 parts of agastache rugosus, 8-12 parts of rhizoma kaempferiae, 8-12 parts of rhizoma nardostachyos, 8-12 parts of ligusticum wallichii and 2-4 parts of mint. The whole composition is a formula mainly comprising pungent and warm medicines, and after the composition is made into a sachet or a device for taking, the effective components of the sachet or the device for taking are continuously worn, and spread all over the whole body through mouth and nose mucosa, skin hair orifices, meridian points and meridians. The traditional Chinese medicine composition has the effects of regulating qi activity and enhancing the disease resistance of the body, so as to expel foul smell in the body and prevent and treat epidemic diseases. Materials are convenient to take and manufacture, and chemical reaction is not needed; after appearance design is carried out on a sachet or a wearable device, the medicine composition can be contained, and the medicine composition can be easily accepted and loved by various people.

Description

Technical Field

[0001] The present invention relates to a sachet pharmaceutical composition for enhancing disease resistance, a preparation method and an application thereof, and particularly relates to the technical field of sachet pharmaceutical compositions. Background Art

[0002] Sachet pharmaceuticals refer to a class of drugs that are made by making traditional Chinese medicinal materials with aromatic odors and medicinal effects into sachets and wearing them on the body to achieve the purposes of preventing diseases, health care, etc. Sachet pharmaceuticals are generally composed of aromatic traditional Chinese medicines. Common sachet pharmaceuticals include mugwort leaf, agastache, eupatorium fortunei, borneol, atractylodes lancea, mint, etc. Mugwort leaf is warm in nature and has the effects of regulating qi and blood, expelling cold and dampness, etc.; agastache can aromatically transform dampness and harmonize the middle-jiao to stop vomiting; eupatorium fortunei can transform dampness and relieve summer heat; borneol can open the orifices and resuscitate, clear heat and relieve pain; atractylodes lancea can dry dampness and strengthen the spleen; mint can disperse wind-heat and clear the head and eyes. These drugs act on the mouth, nose, skin and pores of the human body through the emitted odors, and have the effects of dispelling filth and detoxifying, resuscitating the mind and repelling mosquitoes, enhancing the body's resistance, etc. For example, wearing a sachet containing drugs such as agastache and mint in summer helps prevent heatstroke and mosquito bites; during the influenza epidemic season, wearing a sachet containing drugs such as mugwort leaf and atractylodes lancea can, to a certain extent, prevent virus invasion. It is convenient to use and has few side effects. It is a unique application form of traditional Chinese medicine external treatment methods, is deeply loved by people, and still plays a unique role in the field of health care and preservation of life to this day.

[0003] Sachet pharmaceuticals generally have a pungent and bitter taste, and also have the effects of moistening the lungs and tonifying the lungs, strengthening the spleen and tonifying the kidneys, dredging the channels and collaterals, strengthening the healthy qi and eliminating pathogenic factors. In addition to making aromatic drugs with the effects of waking the spleen and moistening the lungs, and dredging the channels and collaterals into sachets, the external use method of sachet pharmaceuticals can also be made into wearing devices (such as knee pads, masks, waistcoats, lumbar protectors, scented crowns, scented pillows, etc.) and worn on the body. Through the ways of inhaling through the mouth and nose and absorbing through the skin and meridian acupoints, the qi mechanism is regulated to be smooth, the channels and collaterals are unobstructed, and the effects of dispelling turbid qi and preventing diseases are exerted.

[0004] As a doctor in a traditional Chinese medicine hospital, the inventor has long been exposed to sachet pharmaceuticals. Through long-term clinical practice, a sachet pharmaceutical composition for enhancing disease resistance has been developed. It has the effects of regulating the qi mechanism and enhancing the body's disease resistance; at the same time, it has many advantages such as economy, beauty, effectiveness, safety, and wide applicability, and is worthy of popularization and application. Summary of the Invention

[0005] The purpose of the present invention is to provide a sachet pharmaceutical composition for enhancing disease resistance, a preparation method and an application thereof, which have the functions of dispersing wind pathogens, aromatically transforming turbidity, opening orifices and relieving pain, clearing and benefiting the head and eyes, and can regulate the qi mechanism and enhance the body's disease resistance after long-term wearing; at the same time, the present invention also discloses a preparation method of the pharmaceutical composition.

[0006] To achieve the above technical purposes and reach the above technical effects, the present invention is realized through the following technical solutions: A fragrant sachet pharmaceutical composition for enhancing disease resistance is composed of the following raw materials in parts by weight: 4-6 parts of sandalwood, 8-12 parts of ligusticum sinense oliv., 16-24 parts of angelica dahurica, 8-12 parts of agastache rugosa, 8-12 parts of kaempferia galanga, 8-12 parts of nardostachys jatamansi, 8-12 parts of chuanxiong rhizome, and 2-4 parts of mentha haplocalyx briq.; Further, the fragrant sachet pharmaceutical composition for enhancing disease resistance is composed of the following raw materials in parts by weight: 5 parts of sandalwood, 10 parts of ligusticum sinense oliv., 20 parts of angelica dahurica, 10 parts of agastache rugosa, 10 parts of kaempferia galanga, 10 parts of nardostachys jatamansi, 10 parts of chuanxiong rhizome, and 3 parts of mentha haplocalyx briq.; Further, the fragrant sachet pharmaceutical composition for enhancing disease resistance is composed of the following raw materials in grams: 5 g of sandalwood, 10 g of ligusticum sinense oliv., 20 g of angelica dahurica, 10 g of agastache rugosa, 10 g of kaempferia galanga, 10 g of nardostachys jatamansi, 10 g of chuanxiong rhizome, and 3 g of mentha haplocalyx briq.; Another object of the present invention is to provide a preparation method of a fragrant sachet pharmaceutical composition for enhancing disease resistance, which includes the following steps: Mix sandalwood, ligusticum sinense oliv., angelica dahurica, agastache rugosa, kaempferia galanga, nardostachys jatamansi, chuanxiong rhizome, and mentha haplocalyx briq. evenly according to the above weight ratio, then grind them into powder, and control the particle size by sieving to obtain the composition powder; Further, the sieving operation is to pass through a 80-100 mesh sieve; the particle size is 0.15-0.18 mm; Another object of the present invention is to provide an application of a fragrant sachet pharmaceutical composition for enhancing disease resistance. The composition powder is filled into a non-woven fabric bag, tied tightly or sealed tightly with a sealing machine, and then filled into a pure cotton cloth bag, and the bag mouth is tightened to obtain a sachet; Further, the application is to directly wear the sachet or make it into a clothing device adapted to the human anatomical structure and then wear it on the body; the clothing device includes knee pads, masks, vests, lumbar protectors, fragrant crowns, and fragrant pillows; Further, the application is to place the sachet or clothing device indoors; The fragrant sachet pharmaceutical composition of the present invention is a modern pharmaceutical composition designed according to the pharmacological properties and compatibility theory of traditional Chinese medicines. The odor tropism of the raw medicinal materials used is as follows: Sandalwood: pungent in taste, warm in nature, attributing to the spleen, stomach, heart, and lung meridians. Its pungent and dispersing, warm and dredging properties mainly play the roles of promoting qi circulation in the middle energizer, appetizing and relieving pain in this formula. It can regulate the qi of the spleen and stomach, and its fragrance can soothe emotions and make people's minds peaceful; Ligusticum sinense oliv.: pungent in taste, warm in nature, attributing to the bladder meridian. It has the effects of expelling wind and cold, dispelling dampness and relieving pain. In the formula, it is mainly used to disperse wind-cold pathogens on the body surface, especially for relieving wind-cold pain in the head. Its pungent and fragrant smell can help the medicinal power reach the head and face; Angelica dahurica: Spicy, warm in nature, enters the lung, stomach, and large intestine meridians. Angelica dahurica has multiple functions such as dispelling cold, dispelling wind and relieving pain, clearing the nasal passages, drying dampness and stopping leukorrhea, and reducing swelling and draining pus. In the formula, it may play the main role of dispelling cold and clearing the orifices, which can improve symptoms such as nasal congestion and runny nose. Its aromatic smell can go up to the head and go to the skin; Patchouli: Spicy, slightly warm in nature, it enters the spleen, stomach, and lung meridians. It can aromatically eliminate dampness, stop vomiting, and relieve heat. In formulas, it is mainly used to eliminate dampness and invigorate the spleen. Its aromatic smell can help improve the dampness of the spleen and stomach, and has a certain effect on relieving nausea and chest tightness caused by heavy dampness. Kaempferia galanga: Spicy in taste, warm in nature, and enters the stomach meridian. It has the effects of promoting qi and warming the middle, promoting digestion, and relieving pain. Its spicy and fragrant nature helps warm the stomach and promote digestion. When combined with sandalwood, it can enhance the effect of promoting qi and harmonizing the stomach, and improve the distension and discomfort in the epigastric region. Nardostachys grandiflora: Spicy and sweet, warm in nature, enters the spleen and stomach meridians. It can relieve pain, relieve depression and invigorate the spleen. In this formula, it mainly plays the role of relieving depression and invigorating the spleen, making the spleen and stomach qi comfortable, and its aroma can also have a certain calming effect; Chuanxiong: Spicy, warm in nature, enters the liver, gallbladder, and pericardium meridians. It has the effects of promoting blood circulation and qi, dispelling wind and relieving pain. Here, Chuanxiong may assist Ligusticum chuanxiong and Angelica dahurica in dispelling wind and relieving pain. At the same time, its function of promoting blood circulation and qi can make qi and blood flow smoothly, which is helpful for other drugs to play their role, especially in improving pain caused by poor qi and blood flow in the head and the whole body; Mint: Spicy, cool in nature, enters the lung and liver meridians. It can dispel wind-heat, clear the head, relieve sore throat and rash, and soothe the liver and promote qi. In this formula dominated by warming drugs, mint plays a role in balancing the medicinal properties, and its cool nature can prevent the whole formula from being too warm and dry. At the same time, the spicy smell of mint also helps to clear the head and dispel wind-heat in the upper part of the body.

[0007] The pharmaceutical composition of the present invention is a formula mainly composed of pungent and warm drugs. The main effects are to dispel cold, dispel wind and relieve pain, eliminate dampness and harmonize the middle, and promote qi and invigorate the spleen. It can be used to prevent and relieve symptoms such as headache, nasal congestion, runny nose, etc. caused by exogenous wind and cold, and also has an improvement effect on stomach distension, nausea, etc. caused by dampness and turbidity of spleen and stomach and qi stagnation. And due to the aromatic smell of the medicine, it also has the effect of calming the mind and refreshing the brain, and can be used to improve mood, relieve fatigue, etc.

[0008] It is more suitable for people with cold constitution, who are easily affected by wind and cold, and have heavy dampness in the spleen and stomach. For example, people who are prone to headaches and nasal congestion in cold weather, or who often feel fullness in the stomach, nausea, and poor appetite.

[0009] Since most of the drugs in the formula are warm in nature, they are not suitable for people with hot constitutions, yin deficiency and excessive fire, and are prone to causing internal heat symptoms, such as dry mouth, sore throat, constipation, etc. Pregnant women should be cautious when using it, because drugs such as Chuanxiong have the effect of promoting blood circulation and will affect the fetus.

[0010] Advantages of the present invention: A sachet pharmaceutical composition for enhancing disease resistance according to the present invention, after continuous wearing, spreads throughout the body along the meridians through the oral and nasal mucous membranes, skin pores, and meridian acupoints. It has the functions of regulating qi movement, enhancing the body's disease resistance, and thus exerting the effects of expelling turbid substances in the body and preventing and treating epidemic diseases. It is convenient to obtain materials for production without undergoing chemical reactions; After the appearance of the sachet or clothing is designed, the pharmaceutical composition of the present invention can be contained, which is easy to be accepted and loved by various groups of people; Of course, it is not necessary for any product implementing the present invention to achieve all the above-mentioned advantages simultaneously. Detailed implementation manners

[0011] To more clearly illustrate the technical solutions of the embodiments of the present invention, the present invention will be described in detail below in combination with the embodiments. The medicinal materials used are as follows: sandalwood, ligusticum sinense, angelica dahurica, agastache rugosa, kaempferia galanga, nardostachys jatamansi, ligusticum wallichii, mint; Embodiment 1 In this embodiment, a sachet pharmaceutical composition for enhancing disease resistance is composed of the following raw materials in parts by weight: 4-6 parts of sandalwood, 8-12 parts of ligusticum sinense, 16-24 parts of angelica dahurica, 8-12 parts of agastache rugosa, 8-12 parts of kaempferia galanga, 8-12 parts of nardostachys jatamansi, 8-12 parts of ligusticum wallichii, 2-4 parts of mint; Embodiment 2 In this embodiment, a sachet pharmaceutical composition for enhancing disease resistance is composed of the following raw materials in parts by weight: 5 parts of sandalwood, 10 parts of ligusticum sinense, 20 parts of angelica dahurica, 10 parts of agastache rugosa, 10 parts of kaempferia galanga, 10 parts of nardostachys jatamansi, 10 parts of ligusticum wallichii, 3 parts of mint; Embodiment 3 In this embodiment, a sachet pharmaceutical composition for enhancing disease resistance is composed of the following raw materials in parts by weight: 5 g of sandalwood, 10 g of ligusticum sinense, 20 g of angelica dahurica, 10 g of agastache rugosa, 10 g of kaempferia galanga, 10 g of nardostachys jatamansi, 10 g of ligusticum wallichii, 3 g of mint; Embodiment 4 In this embodiment, based on the above Embodiments 1-3, a preparation method of a sachet pharmaceutical composition for enhancing disease resistance: includes the following steps: S1: Mix sandalwood, ligusticum sinense, angelica dahurica, agastache rugosa, kaempferia galanga, nardostachys jatamansi, ligusticum wallichii, and mint evenly according to the weight ratio and then grind them into powder. Control the particle size by sieving to obtain the composition powder; the sieving operation is to pass through an 80-100 mesh sieve; the particle size of the composition powder is 0.15-0.18 mm; S2: Put the composition powder obtained in S1 into a non-woven bag, tie it tightly or seal it with a sealing machine, and then put it into a pure cotton bag and tighten the bag mouth to obtain a sachet; Embodiment 5 In this embodiment, based on the above embodiments 1-4, an application of a fragrant sachet pharmaceutical composition for enhancing disease resistance is provided. The sachet is directly worn or made into a clothing device adapted to the human anatomical structure and then worn on the body. The clothing device includes knee pads, masks, and vests. In this embodiment, the sachet or the clothing device can also be placed indoors.

[0012] Example 6 The main clinical effects of the components of the pharmaceutical composition of the present invention are as follows: Sandalwood has significant clinical effects in aspects such as antibacterial, anti-inflammatory, sedative, and skin care; the main pharmacological effects of Ligusticum sinense include anti-inflammatory, analgesic, antibacterial, antiviral, improving microcirculation, antioxidant, regulating immunity, spasmolysis, and anti-allergy, etc.; Angelica dahurica has significant clinical effects in aspects such as expelling wind and cold, relieving pain, antibacterial and anti-inflammatory, etc.; Nardostachys jatamansi is mainly used for regulating qi and relieving pain, relieving depression and awakening the spleen, calming the nerves, etc., and has effects such as antibacterial, anti-inflammatory, and anti-arrhythmia; Chuanxiong is mainly used clinically for promoting blood circulation to remove blood stasis, promoting qi circulation to relieve pain, improving cardiovascular and cerebrovascular functions, antiplatelet aggregation, etc., and is a commonly used medicine for treating blood stasis syndrome, cardiovascular and cerebrovascular diseases, and rheumatism and arthralgia; Mentha haplocalyx is mainly used clinically for dispersing wind-heat, clearing the throat, promoting eruption and relieving itching, soothing the liver and relieving depression, etc., and has effects such as anti-inflammatory and analgesic, promoting digestion, antibacterial and antiviral, etc.; Pogostemon cablin is mainly used for resolving dampness, relieving summer heat, stopping vomiting, etc., and has effects such as antibacterial, anti-inflammatory, and promoting digestion. In summary, the fragrant sachet pharmaceutical composition has the functions of dispersing wind pathogens, aromatic turbidity resolution, opening orifices and relieving pain, and clearing the head and eyes.

[0013] Example 7 Regarding the safety and precautions of the components of the present invention: The traditional Chinese medicines contained in the fragrant sachet pharmaceutical composition, such as sandalwood, Angelica dahurica, Mentha haplocalyx, Kaempferia galanga, and Pogostemon cablin, are included in the list of dual-purpose varieties of medicine and food issued by the "Notice of the Ministry of Health on Further Standardizing the Management of Health Food Raw Materials" (No. 51

[2002] of the Ministry of Health, Law and Supervision). They can be used as medicinal materials for treating diseases, or as food or condiments for daily diet. They have high safety and wide applications. Reasonable use of these medicinal materials can not only meet the daily diet needs but also play a health care role, with high safety and being widely suitable for most people. However, due to physical differences, some people may be allergic to certain of these traditional Chinese medicines, and attention should be paid when using them.

[0014] Example 8 Typical cases Case 1: A patient with recurrent colds: Female, 32 years old, a teacher; Chief complaint: Prone to colds in winter in the past 3 years, 1-2 times a month, accompanied by nasal congestion, runny nose, and fatigue; Diagnosis: Recurrent upper respiratory tract infection (traditional Chinese medicine syndrome differentiation belongs to qi deficiency and insecurity of the defensive qi on the body surface); Treatment: Wear the sachet of the present invention (formula of Example 3) for 8 hours a day for 3 months; Effect: Only had a cold once within 3 months, with significantly reduced symptoms, less nasal congestion and runny nose, and improved energy; Conclusion: The continuous action of the sachet can enhance the fixation of the defensive qi on the body surface and reduce the frequency of exogenous infections.

[0015] Case 2: Patient with chronic rhinitis: Male, 45 years old, driver; Chief complaint: Perennial nasal congestion, sneezing in the morning, and reduced sense of smell for 5 years; Diagnosis: Allergic rhinitis (TCM syndrome differentiation: wind-cold attacking the nasal orifices); Treatment: Wearing a sachet (formula of Example 3) + self-made mask (containing 3 g of medicinal powder), 6 hours per day; Effect: Nasal congestion relieved after 1 week, sneezing reduced after 2 weeks, and sense of smell restored after 1 month; Conclusion: The medicine is absorbed through the oral and nasal mucosa, effectively improving the state of nasal orifice obstruction.

[0016] Case 3: Patient with fatigue syndrome: Female, 28 years old, programmer; Chief complaint: Persistent fatigue and inattention for 1 year, accompanied by headache and shallow sleep; Diagnosis: Chronic fatigue syndrome (TCM syndrome differentiation: liver depression and spleen deficiency, failure of clear yang to ascend); Treatment: Wearing a sachet (formula of Example 3) + fragrant crown (containing 5 g of medicinal powder), 10 hours per day; Effect: Spirit improved in the morning after 2 weeks, headache frequency decreased by 70% after 1 month, and sleep quality improved; Conclusion: The fragrance of the medicine is conducted through the meridians of the head and face, playing the role of ascending clear and descending turbid, and refreshing the mind and calming the nerves.

[0017] Case 4: Patient with spleen and stomach weakness: Male, 60 years old, retired cadre; Chief complaint: Long-term epigastric fullness, loss of appetite, and loose stools for 2 years; Diagnosis: Functional dyspepsia (TCM syndrome differentiation: spleen deficiency with dampness obstruction); Treatment: Wearing a sachet (formula of Example 3) + fragrant pouch (containing 8 g of medicinal powder), 12 hours per day; Effect: Abdominal distension relieved after 1 week, appetite improved after 2 weeks, and stools formed after 1 month; Conclusion: The medicine is absorbed through the abdominal acupoints, enhancing the transportation and transformation functions of the spleen and stomach, and resolving damp turbidity.

[0018] Case 5: Patient with rheumatoid arthritis: Female, 55 years old, houseworker; Chief complaint: Cold pain in both knees, aggravated by cold, and limited mobility for 3 years; Diagnosis: Knee osteoarthritis (TCM syndrome differentiation: cold-dampness obstructing the meridians); Treatment: Wearing a sachet (formula of Example 3) + knee protector (containing 10 g of medicinal powder), 8 hours per day; Effect: Pain relieved after 1 week, joint range of motion increased after 2 weeks, and recurrence frequency decreased after 3 months; Conclusion: The medicine penetrates through the skin, warming and dredging the meridians, and dispelling cold-dampness pathogens.

[0019] Supplementary instructions: 1. All cases excluded severe organic diseases, and no other similar drugs were used during the treatment period; 2. The onset time of the medicine varied from 3 to 14 days, and continuous use had a better effect; 3. It is recommended to replace the medicinal powder in the sachet every 2 weeks to maintain the medicinal effect; 4. Special populations (pregnant women, allergic constitution) need to use it under the guidance of a doctor. These cases verified the practical application value of the invention through specific clinical scenarios and met the requirements of the patent examination for examples.

[0020] The preferred embodiments of the present invention disclosed above are only used to help illustrate the present invention. The preferred embodiments do not describe all the details in detail, nor do they limit the invention to the specific embodiments described. Obviously, many modifications and variations can be made according to the content of this specification. These embodiments are selected and specifically described in this specification to better explain the principles and practical applications of the present invention, so that those skilled in the art can well understand and utilize the present invention. The present invention is only limited by the claims and their full scope and equivalents.

Claims

1. A fragrant medicinal composition for enhancing disease resistance, characterized in that: The raw materials are composed of the following parts by weight: 4-6 parts of sandalwood, 8-12 parts of Ligusticum chuanxiong, 16-24 parts of Angelica dahurica, 8-12 parts of Patchouli, 8-12 parts of Kaempferia galanga, 8-12 parts of Nardostachys grandiflora, 8-12 parts of Ligusticum chuanxiong and 2-4 parts of mint.

2. The disease resistance enhancing fragrant medicinal composition according to claim 1, characterized in that: The incense and medicine composition for enhancing disease resistance is composed of the following raw materials in parts by weight: 5 parts of santalin, 10 parts of ligusticum chuanxiong, 20 parts of angelica dahurica, 10 parts of patchouli, 10 parts of galangal, 10 parts of nard, 10 parts of ligusticum chuanxiong, and 3 parts of mint.

3. The disease resistance enhancing fragrant medicinal composition according to claim 1, characterized in that: The incense and medicine composition for enhancing disease resistance is composed of the following raw materials in grams: 5g of sandalwood, 10g of Ligusticum chuanxiong, 20g of Angelica dahurica, 10g of Patchouli, 10g of Kaempferia galanga, 10g of Nardostachys grandiflora, 10g of Ligusticum chuanxiong, and 3g of mint.

4. A method for preparing a fragrant medicinal composition for enhancing disease resistance, characterized in that: The following steps are involved: Sandalwood, Ligusticum chuanxiong, Angelica dahurica, Patchouli, Kaempferia galanga, Nardostachys grandiflora, Ligusticum chuanxiong and Mentha are mixed evenly according to weight proportion, ground into powder, and sieved to control particle size to obtain composite powder.

5. A method for preparing a fragrant medicinal composition for enhancing disease resistance as claimed in claim 4, characterized in that: The sieving operation is to pass through a 80-100 mesh sieve; the particle size of the composition powder is 0.15-0.18 mm.

6. An application of a fragrant medicinal composition for enhancing disease resistance, characterized in that: Using the composition powder as claimed in claim 4, the composition powder is put into a non-woven bag, tied tightly with a knot or sealed with a sealing machine, put into a pure cotton bag, and tighten the bag mouth to obtain a sachet; the sachet contains a fragrant medicine composition for enhancing disease resistance; The sachet is worn on a person's body, or is made into a device adapted to the anatomical structure of the human body and then worn on a person's body.

7. The use of a fragrant medicinal composition for enhancing disease resistance as claimed in claim 6, characterized in that: The sachet is placed indoors.