Blood detection device for experimental animals
By designing the driving components of multiple sets of gears, different shaking speeds and number of turns for different specifications of blood collection tubes are achieved, which solves the problem that existing devices cannot flexibly cope with multiple specifications of blood collection tubes, and improves the accuracy and efficiency of blood detection.
Patent Information
- Application Number
- CN202510330102.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-20
- Publication Date
- 2025-06-17
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Existing blood detection devices cannot flexibly deal with different specifications of blood collection vessels, resulting in improper shaking speed, which may lead to hemolysis or uneven mixing problems.
A blood detection device including a driving component is designed. By setting up multiple sets of secondary gears and main gears, each set of gears has different tooth ratios, and different shaking speeds and number of turns of blood collection tubes of different specifications are achieved to ensure uniform mixing of blood and anticoagulant.
Through this device, it is possible to ensure uniform mixing of blood collection tubes of different specifications, avoid hemolysis or uneven mixing, and improve the accuracy and efficiency of detection.
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Figure CN120160880A_ABST
Abstract
Description
Technical Field
[0001] The present invention belongs to the field of blood detection, and specifically relates to a blood detection device for experimental animals. Background Art
[0002] In order to obtain new knowledge in the fields of biology, medicine, etc., scientific research is carried out through experiments on animals. In the experiment, in order to evaluate the health status of animals, diagnose diseases, monitor the treatment effect, and study physiological functions, etc., a blood detection device is required to detect the blood of experimental animals to obtain detailed information about blood components such as red blood cells, white blood cells, and platelets, so as to accurately judge the physical condition of experimental animals and provide reliable data support for subsequent research.
[0003] A patent application with the publication number CN117589977A discloses a blood vortex oscillation assisted detection device for animal disease detection, including a housing, and also includes a fixed disk; a driving motor installed on the fixed disk; a vertical rod installed on the fixed disk; bevel gears provided on the vertical rod and the driving motor; a disk and a placement groove installed on the vertical rod; a clamping assembly arranged in the placement groove; after placing the blood collection tube in the placement groove and clamping the blood collection tube through the clamping assembly, the blood and anticoagulant in the blood collection tube are mixed by an oscillator, and after mixing for a period of time, the blood can be detected.
[0004] After collecting blood from experimental animals, before detection, the blood collection tube needs to be shaken to mix the blood and anticoagulant in the blood collection tube to avoid the problem of blood coagulation during detection. The above device can only mix blood samples and anticoagulants of the same specification and cannot meet the needs of different specification samples. However, in animal experiments, different breeds of animals are usually used, and the blood collection volume of different animals is different. Therefore, the specifications of the blood collection tubes used are different, resulting in the inability of the existing device to flexibly cope with multi-specification requirements. Using the same shaking speed for blood collection tubes of different specifications will cause problems such as excessive shaking speed resulting in hemolysis or too low shaking speed resulting in uneven mixing.
[0005] Therefore, the present invention provides a blood detection device for experimental animals. Summary of the Invention
[0006] In order to make up for the deficiencies of the prior art and solve the problem that the existing device in the background art cannot flexibly cope with multi-specification requirements.
[0007] The technical solution adopted by the present invention to solve its technical problems is as follows: A blood detection device for experimental animals described in the present invention includes a detector body and a sampling needle, and further includes a sample mixing part for mixing animal blood and anticoagulant. The sample mixing part includes: a disc rotatably installed on the detector body; a plurality of fixed seats installed on the disc, and a clamping assembly rotatably installed on the fixed seat; a driving assembly installed on the fixed seat, the driving assembly includes a main shaft rotatably installed on the fixed seat and a secondary shaft for driving the clamping jaw to rotate, a plurality of groups of secondary gears and main gears are respectively installed on the secondary shaft and the main shaft, the tooth ratio of each group of secondary gears and main gears is different, the secondary shaft adopts a telescopic structure, under the condition that the rotation speed of the main shaft remains unchanged, different groups of the secondary gears and the main gears are engaged, and the rotation speed of the secondary shaft is different.
[0008] Preferably, the driving assembly further includes: a handle rotatably installed on the fixed seat, the handle is fixedly installed on the clamping assembly; a first rotating ring rotatably installed on the fixed seat; a long rod slidably installed on the fixed seat, the long rod is threadedly connected to the first rotating ring, the clamping assembly includes a clamping jaw, the long rod passes through the handle and is rotatably connected to the clamping jaw of the clamping assembly; a second rotating ring rotatably installed on the fixed seat, a belt for transmission is installed between the first rotating ring and the second rotating ring; a pull rod threadedly connected to the second rotating ring; a ring rotatably installed on the secondary shaft, the ring is located at the movable end of the secondary shaft, and a connecting rod is rotatably connected between the ring and the pull rod.
[0009] Preferably, the driving assembly further includes: a first gear fixedly installed on the handle; a mounting plate slidably installed on the fixed seat; a plurality of rack plates installed on the mounting plate, the rack plates are used to drive the first gear to rotate, and part of the rack plates are slidably connected to the mounting plate; a plurality of switches installed in the handle, different switches are used to control the sliding of different rack plates, and the long rod has a protruding part for triggering the switch.
[0010] Preferably, the driving assembly further includes: a slide plate slidably mounted on the fixed seat; a groove formed in the mounting plate, there are two sets of the mounting plate and the rack plate, and they are symmetrically distributed on both sides of the first gear; two insertion rods slidably mounted on the slide plate, the insertion rods are used in cooperation with the groove; a lead screw rotatably mounted on the fixed seat, the lead screw is used to drive the slide plate to slide up and down, a chain belt is installed between the lead screw and the secondary shaft, and they are driven by the chain belt; a cam and a first ratchet rotatably mounted on the slide plate, the cam is fixedly connected to the first ratchet, the cam is used to push the insertion rod to slide relative to the slide plate, a first spring is installed between the insertion rod and the slide plate; a first pawl for driving the first ratchet to rotate, the first pawl is rotatably mounted on the fixed seat, and the first ratchet is within the moving range of the first pawl.
[0011] Preferably, the sample mixing part further includes: a monitoring component installed on the detector body, and the monitoring component is used to observe whether the blood in the blood collection tube is hemolyzed.
[0012] Preferably, the sample mixing part further includes: a third rotating ring rotatably mounted on the fixed seat; a knocking rod slidably mounted up and down on the fixed seat, a chute is formed in the knocking rod, there are protrusions on the third rotating ring, and a second spring is provided between the third rotating ring and the knocking rod. The third rotating ring rotates and drives the knocking rod to reciprocally knock up and down through the dual action of the protrusion and the second spring; a toothed plate slidably mounted up and down on the detector body; a gear set for driving the third rotating ring to rotate, and the gear set is rotatably mounted on the fixed seat.
[0013] Preferably, the sample mixing part further includes: a round rod installed on the fixed seat; two third gears rotatably mounted on the round rod, the two third gears are driven unidirectionally, and one of the third gears is meshed with the third rotating ring; a second ratchet rotatably mounted on the fixed seat, the second ratchet is meshed with the third gear, and there is a convex block on the second ratchet; a third ratchet rotatably mounted on the fixed seat, an inductor is fixedly installed on the third ratchet, and the inductor is used in cooperation with the convex block; a second pawl slidably mounted on the fixed seat, the second pawl is used to limit the unidirectional rotation of the third ratchet and the second ratchet; a third telescopic rod fixedly installed on the fixed seat, the third telescopic rod is used to drive the second pawl to slide; a third spring installed on the third ratchet, the second ratchet and the fixed seat; a fourth gear rotatably mounted on the fixed seat, and the fourth gear is used to drive the third ratchet to rotate.
[0014] The beneficial effects of the present invention are as follows:
[0015] 1. A blood detection device for experimental animals according to the present invention realizes different shaking speeds and shaking cycles for blood collection tubes of different specifications by setting a driving component, ensuring uniform mixing of blood and anticoagulant, avoiding hemolysis or uneven mixing, and improving the accuracy and efficiency of detection.
[0016] 2. A blood detection device for experimental animals according to the present invention enables the sampling tube to rotate and mix in different directions by setting a plug rod and a groove, further ensuring sufficient mixing of the liquid in the blood collection tube.
[0017] 3. A blood detection device for experimental animals according to the present invention is provided with a knocking rod. After the monitoring component detects that there are bubbles in the blood collection tube, the blood collection tube is knocked, and the bubbles rise to the top of the blood collection tube through knocking, thereby eliminating the bubbles, ensuring that the blood sample in the blood collection tube is sufficient and free from bubble interference, and maintaining the purity of the sample and the accuracy of detection.
[0018] 4. A blood detection device for experimental animals according to the present invention detects the frequencies of hemolysis and bubble phenomena on the fixed seat within a certain period of time by setting a sensor and a convex block, so as to avoid damage to the components on the fixed seat, resulting in hemolysis and bubble phenomena in the blood collection tube and affecting the detection results. BRIEF DESCRIPTION OF THE DRAWINGS
[0019] The present invention will be further described below with reference to the accompanying drawings.
[0020] Figure 1 is a perspective view of Embodiment 1 of the present invention;
[0021] Figure 2 is a schematic position diagram of the monitoring component of the present invention;
[0022] Figure 3 is a schematic structural diagram of the fixed seat and the clamping jaws of the present invention;
[0023] Figure 4 is a sectional view of the fixed seat of the present invention;
[0024] Figure 5 is a schematic position diagram of the groove of the present invention;
[0025] Figure 6 is a schematic position diagram of the first ratchet of the present invention;
[0026] Figure 7 is a schematic structural diagram of the cam of the present invention;
[0027] Figure 8 is a sectional view of the handle of the present invention;
[0028] Figure 9It is a schematic structural diagram of the knocking rod and the third ring of the present invention;
[0029] Figure 10 It is a schematic structural diagram of the third gear and the gear set of the present invention;
[0030] In the figure: 1. Detector body; 2. Sampling needle; 3. Sample mixing part; 31. Disc; 32. Fixed seat; 33. Driving component; 331. Main shaft; 332. Sub-shaft; 333. Sub-gear; 334. Main gear; 335. Handle; 336. First rotating ring; 337. Long rod; 338. Second rotating ring; 339. Pull rod; 3310. Ring; 3311. Connecting rod; 3312. First gear; 3313. Mounting plate; 3314. Rack plate; 3315. Switch; 3316. Slide plate; 3317. Groove; 3318. Plug rod; 3319. Lead screw; 3320. Cam; 3321. First ratchet; 3322. First spring; 3323. First pawl; 34. Monitoring component; 35. Third rotating ring; 36. Knocking rod; 37. Second spring; 38. Tooth plate; 39. Gear set; 310. Round rod; 311. Third gear; 312. Second ratchet; 313. Protrusion; 314. Third ratchet; 315. Inductor; 316. Second pawl; 317. Third telescopic rod; 318. Third spring; 319. Fourth gear; 4. Clamping component; 41. Claw. Detailed implementation mode
[0031] In order to make the technical means, creative features, achieved purposes and effects of the present invention easy to understand, the present invention will be further described below in conjunction with specific implementation modes.
[0032] As Figures 1 - 10 shown, a blood detection device for experimental animals according to an embodiment of the present invention includes a detector body 1 and a sampling needle 2, and further includes a sample mixing part 3 for mixing animal blood and anticoagulant. The sample mixing part 3 includes: a disc 31 rotatably installed on the detector body 1; a plurality of fixed seats 32 installed on the disc 31, and a clamping component 4 rotatably installed on the fixed seat 32; a driving component 33 installed on the fixed seat 32, and the driving component 33 includes a main shaft 331 rotatably installed on the fixed seat 32 and a sub-shaft 332 for driving the claw 41 to rotate. A plurality of groups of sub-gears 333 and main gears 334 are respectively installed on the sub-shaft 332 and the main shaft 331. The tooth ratios of each group of sub-gears 333 and main gears 334 are different. The sub-shaft 332 adopts a telescopic structure. Under the condition that the rotation speed of the main shaft 331 remains unchanged, different groups of sub-gears 333 and main gears 334 are engaged, and the rotation speed of the sub-shaft 332 is different.
[0033] Specifically, after collecting blood from experimental animals and before detection, the blood collection tube needs to be shaken to mix the blood and anticoagulant in the tube to avoid blood coagulation during detection. Existing devices can only mix blood samples and anticoagulants of the same specification and cannot meet the needs of different specifications of samples. However, different breeds of animals are usually used in animal experiments, and the blood collection volumes of different animals are different. Therefore, the specifications of the blood collection tubes used are different, resulting in the inability of existing devices to flexibly meet the requirements of multiple specifications. Using the same shaking speed for blood collection tubes of different specifications will cause problems such as excessive shaking speed resulting in hemolysis or too low shaking speed resulting in uneven mixing;
[0034] The detector body 1 and the sampling needle 2 can adopt existing blood detection instruments such as blood routine analyzers. In the initial state, the lowermost sub-gear 333 meshes with the main gear 334. After blood collection, the blood collection tube is placed in the jaw 41 and clamped by the jaw 41. Subsequently, according to the specifications of different blood collection tubes, the sub-shaft 332 is controlled to extend and retract so that the corresponding sub-gear 333 meshes with the main gear 334, so that the rotation speeds of the main shafts 331 are the same. Under the condition that the tooth ratios of the meshing teeth of the sub-gear 333 and the main gear 334 are different, the rotation speed of the sub-shaft 332 is different. Therefore, the rotation speed of the jaw 41 is different, thus realizing the precise mixing of blood collection tubes of different specifications. While mixing the blood and anticoagulant in the blood collection tube, the control disc 31 is rotated. When the control disc 31 rotates below the sampling needle 2, the mixing is completed. The sampling needle 2 is controlled to sample the blood collection tube, and the detector body 1 performs detection. After the detection is completed, the control disc 31 is controlled to continue rotating to sample and detect the next blood collection tube, that is, the continuous mixing and detection actions of blood collection tubes of multiple specifications are realized;
[0035] By setting the driving component 33, different shaking speeds are adopted for blood collection tubes of different specifications, ensuring uniform mixing of blood and anticoagulant, avoiding hemolysis or uneven mixing, and improving the accuracy and efficiency of detection.
[0036] Such as Figure 4 and Figure 8As shown in the figure, the driving component 33 further includes: a handle 335 rotatably mounted on the fixed seat 32, and the handle 335 is fixedly mounted on the clamping component 4; a first rotating ring 336 rotatably mounted on the fixed seat 32; a long rod 337 slidably mounted on the fixed seat 32, and the long rod 337 is threadedly connected to the first rotating ring 336. The clamping component 4 includes a clamping jaw 41, and the long rod 337 passes through the handle 335 and is rotatably connected to the clamping jaw 41 of the clamping component 4; a second rotating ring 338 rotatably mounted on the fixed seat 32, and a belt for transmission is mounted between the first rotating ring 336 and the second rotating ring 338; a pull rod 339 threadedly connected to the second rotating ring 338; a circular ring 3310 rotatably mounted on the secondary shaft 332, the circular ring 3310 is located at the movable end of the secondary shaft 332, and a connecting rod 3311 is rotatably connected between the circular ring 3310 and the pull rod 339.
[0037] Specifically, when the blood collection tube is clamped by the clamping jaws 41 of the clamping component 4, during the process of the clamping jaws 41 approaching each other, the movement of the clamping jaws 41 drives the long rod 337 to move synchronously. Since the long rod 337 is threadedly connected to the first rotating ring 336, the first rotating ring 336 rotates. The rotation of the first rotating ring 336 drives the second rotating ring 338 to rotate synchronously. Therefore, the pull rod 339 moves left and right relative to the secondary shaft 332. The movement of the pull rod 339 can drive the pull rod 339 to rotate, and the rotation of the pull rod 339 causes the circular ring 3310 to move up and down. Since the rotating ring moves up and down, the secondary shaft 332 contracts upward. Due to blood collection tubes of different specifications, the distances that the clamping jaws 41 move are different. Therefore, the distances that the secondary shaft 332 contracts upward are also different. The meshing main gear 334 and secondary gear 333 are different. Therefore, the rotation speeds of the secondary shaft 332 are different, and the rotation speeds of the clamping jaws 41 are different.
[0038] As Figure 4 、 Figure 5 and Figure 8 shown in the figure, the driving component 33 further includes: a first gear 3312 fixedly mounted on the handle 335; a mounting plate 3313 slidably mounted on the fixed seat 32; a plurality of rack plates 3314 mounted on the mounting plate 3313, and the rack plates 3314 are used to drive the first gear 3312 to rotate. Some of the rack plates 3314 are slidably connected to the mounting plate 3313; a plurality of switches 3315 mounted in the handle 335, and different switches 3315 are used to control the sliding of different rack plates 3314. The long rod 337 has a protruding part for triggering the switch 3315.
[0039] Specifically, the smaller the specification of the blood collection tube, the more switches 3315 triggered by the long rod 337. Through different switches 3315, the contraction of different second telescopic rods is controlled. After the second telescopic rods contract, they can push the corresponding rack plates 3314 to move, so that the corresponding rack plates 3314 and the first gear 3312 are not in the same plane. Subsequently, the control mounting plate 3313 slides up and down. The up and down sliding of the mounting plate 3313 drives the rack plate 3314 to move synchronously. When the rack plate 3314 moves up and down, it drives the first gear 3312 to rotate reciprocally. When the number of reciprocating movements of the mounting plate 3313 up and down remains unchanged, the fewer the rack plates 3314 meshing with the first gear 3312 on the mounting plate 3313, the fewer the number of rotations of the first gear 3312, that is, the fewer the number of rotations of the blood collection tube, so as to further achieve the precise control of blood collection tubes of different specifications, ensure the best mixing effect, and avoid the occurrence of hemolysis or uneven mixing.
[0040] As Figures 4 - 8 shown, the driving assembly 33 further includes: a sliding plate 3316 slidably mounted on the fixed seat 32; a groove 3317 opened on the mounting plate 3313. There are two sets of the mounting plate 3313 and the rack plate 3314, and they are symmetrically distributed on both sides of the first gear 3312; two inserting rods 3318 slidably mounted on the sliding plate 3316, and the inserting rods 3318 are used in cooperation with the groove 3317; a lead screw 3319 rotatably mounted on the fixed seat 32, and the lead screw 3319 is used to drive the sliding plate 3316 to slide up and down. A chain belt is installed between the lead screw 3319 and the secondary shaft 332 and is driven by the chain belt; a cam 3320 and a first ratchet 3321 rotatably mounted on the sliding plate 3316, the cam 3320 is fixedly connected to the first ratchet 3321, and the cam 3320 is used to push the inserting rod 3318 to slide relative to the sliding plate 3316. A first spring 3322 is installed between the inserting rod 3318 and the sliding plate 3316; a first pawl 3323 for driving the first ratchet 3321 to rotate, the first pawl 3323 is rotatably mounted on the fixed seat 32, and the first ratchet 3321 is within the moving range of the first pawl 3323.
[0041] Specifically, the screw rod 3319 adopts a reciprocating screw rod 3319. In the initial state, the insertion rod 3318 on one side of the slide plate 3316 is inserted into the groove 3317 of the mounting plate 3313. During mixing, the main gear 334 rotates, driving the sub-gear 333 and the secondary shaft 332 to rotate synchronously. The secondary shaft 332 drives the screw rod 3319 to rotate through the chain belt. The rotation of the screw rod 3319 drives the slide plate 3316 to move up and down reciprocatingly. The slide plate 3316 moves up and down, and the mounting plate 3313 and the rack plate 3314 can be driven to move synchronously through the insertion rod 3318 to realize the rotation of the No. 1 gear 3312, the clamping claw 41 and the blood collection tube. When the slide plate 3316 moves to the original position, the No. 1 ratchet 3321 and the No. 1 ratchet 3323 The cam 3320 rotates synchronously with the rod 3318 on the other side and pushes the rod 3318 to insert into the groove 3317 of the mounting plate 3313 on the other side. The rod 3318 on the initial side returns to its original position under the elastic force of the spring 3322, i.e., slides out of the groove 3317. When the slide plate 3316 reciprocates up and down again, the mounting plate 3313 and the rack plate 3314 on the other side are driven up and down by the rod 3318, so that the blood collection tube reciprocates to the other side. The rod 3318 and the groove 3317 are arranged so that the sampling tube can rotate and mix in different directions, thereby further ensuring sufficient mixing of the liquid in the blood collection tube.
[0042] like Figure 2 As shown, the sample mixing unit 3 further includes: a monitoring component 34 installed on the detector body 1, and the monitoring component 34 is used to observe whether the blood in the blood collection tube is hemolyzed.
[0043] Specifically, the monitoring component 34 uses an existing industrial camera and its system, which can take pictures and compare them to determine whether there is a problem. The monitoring component 34 observes the blood in each blood collection tube. When hemolysis occurs, the monitoring component 34 transmits the image information to the operator in real time, so as to detect the problem in time, find the cause of the data abnormality, and avoid affecting the experimental results.
[0044] like Figure 9 and Figure 10 As shown, the sample mixing part 3 also includes: a No. 3 swivel ring 35 rotatably mounted on the fixed base 32; a knocking rod 36 slidably mounted on the fixed base 32 up and down, a sliding groove is provided on the knocking rod 36, the No. 3 swivel ring 35 contains a protrusion, a No. 2 spring 37 is provided between the No. 3 swivel ring 35 and the knocking rod 36, the No. 3 swivel ring 35 rotates through the dual effects of the protrusion and the No. 2 spring 37, driving the knocking rod 36 to reciprocate up and down; a toothed plate 38 slidably mounted on the detector body 1 up and down; a gear set 39 for driving the No. 3 swivel ring 35 to rotate, and the gear set 39 is rotatably mounted on the fixed base 32.
[0045] Specifically, due to factors such as too fast shaking speed, improper blood collection technique, and improper operation method, after the blood collection tube is mixed evenly, air bubbles will be generated inside the blood collection tube. The existence of air bubbles will occupy the space inside the blood collection tube, which may lead to insufficient blood sample actually entering the instrument and affect the test results;
[0046] After the monitoring component 34 detects that there are air bubbles in the blood collection tube, it controls the toothed plate 38 to slide downward. When the fixed seat 32 drives the rotating ring to rotate to this position, it can drive the gear set 39 to rotate. The rotation of the gear set 39 drives the third rotating ring 35 to rotate. The rotation of the rotating ring makes the knocking rod move up and down reciprocally to knock on the blood collection tube. Through knocking, the air bubbles rise to the top of the blood collection tube, thereby eliminating the air bubbles, ensuring that the blood sample in the blood collection tube is sufficient and free from air bubble interference, and maintaining the purity of the sample and the accuracy of the test.
[0047] As Figure 10 shown, the sample mixing part 3 further includes: a round rod 310 installed on the fixed seat 32; two third gears 311 rotatably installed on the round rod 310, with one-way transmission between the two third gears 311, and one of the third gears 311 is meshed and connected with the third rotating ring 35; a second ratchet 312 rotatably installed on the fixed seat 32, the second ratchet 312 is meshed and connected with the third gear 311, and a convex block 313 is arranged on the second ratchet 312; a third ratchet 314 rotatably installed on the fixed seat 32, an inductor 315 is fixedly installed on the third ratchet 314, and the inductor 315 is used in cooperation with the convex block 313; a second pawl 316 slidably installed on the fixed seat 32, and the second pawl 316 is used to limit the one-way rotation of the third ratchet 314 and the second ratchet 312; a third telescopic rod 317 fixedly installed on the fixed seat 32, and the third telescopic rod 317 is used to drive the second pawl 316 to slide; a third spring 318 installed on the third ratchet 314, the second ratchet 312 and the fixed seat 32; a fourth gear 319 rotatably installed on the fixed seat 32, and the fourth gear 319 is used to drive the third ratchet 314 to rotate.
[0048] Specifically, the second pawl 316 limits the third ratchet 314 to only rotate counterclockwise, and the second ratchet 312 can only rotate clockwise. In the initial state, the second pawl 316 is meshed with the second ratchet 312 and the third ratchet 314. When the monitoring component 34 observes that the blood in the blood collection tube shows hemolysis, it controls the toothed plate 38 to move downward to be meshed with the fourth gear 319. Subsequently, when the fixed seat 32 drives the blood collection tube and the fourth gear 319 away, the fourth gear 319 rotates. The rotation of the fourth gear 319 drives the third ratchet 314 to rotate counterclockwise by an angle (taking the perspective from top to bottom in Figure 10 as an example), so that the distance between the inductor 315 and the convex block 313 decreases, and at this time the third spring 318 is stretched;
[0049] When the monitoring component 34 observes bubbles in the blood collection tube, the tooth plate 38 is controlled to move downward to mesh with the gear set 39. Then, when the fixed seat 32 rotates with the blood collection tube and the gear set 39, the gear set 39 rotates. The rotation of the gear set 39 drives the third rotating ring 35 to rotate. The third rotating ring 35 drives the third gear 311 to rotate synchronously. The third gear 311 drives the second ratchet 312 to rotate clockwise for a certain angle, so that the distance between the sensor 315 and the protrusion 313 is reduced. At this time, the third spring 318 is stretched.
[0050] During operation, the third telescopic rod 317 is intermittently extended and retracted, and the extension and retraction of the third telescopic rod 317 can make the second pawl 316 not contact the third ratchet 314 and the second ratchet 312 for a while. At this time, the third ratchet 314 and the second ratchet 312 can rotate clockwise and counterclockwise respectively under the action of the elastic force of the third spring 318, thereby increasing the distance between the sensor 315 and the protrusion 313;
[0051] If hemolysis and bubbles occur more frequently on the fixing base 32, the speed at which the distance between the sensor 315 and the protrusion 313 is smaller will be greater than the speed at which the distance between the sensor 315 and the protrusion 313 increases, until the sensor 315 contacts the protrusion 313. At this time, the sensor 315 is triggered and a signal can be transmitted to the staff to check whether there is a problem with the components on the fixing base 32, so as to avoid shaking the blood collection tube too fast.
[0052] If the hemolysis and bubble phenomena on the fixing seat 32 are less, the speed at which the distance between the sensor 315 and the protrusion 313 is smaller will be smaller than the speed at which the distance between the sensor 315 and the protrusion 313 is increased, and the sensor 315 will not be triggered;
[0053] By providing the sensor 315 and the bump 313, the frequency of hemolysis and bubble generation on the fixing seat 32 within a period of time is detected to avoid damage to components on the fixing seat 32, which may cause hemolysis and bubble generation in the blood collection tube and affect the detection results.
[0054] Working principle: In the initial state, the lower auxiliary gear 333 meshes with the main gear 334. After blood collection, the blood collection tube is placed in the jaw 41, and the blood collection tube is clamped by the jaw 41. When the blood collection tube is clamped by the jaw 41 of the clamping assembly 4 and the jaws 41 approach each other, the movement of the jaws 41 drives the long rod 337 to move synchronously. Since the long rod 337 is threadedly connected to the first rotating ring 336, the first rotating ring 336 rotates. The rotation of the first rotating ring 336 drives the second rotating ring 338 to rotate synchronously. Therefore, the pull rod 339 moves left and right relative to the auxiliary shaft 332. The movement of the pull rod 339 can drive the pull rod 339 to rotate. The rotation of the pull rod 339 causes the ring 3310 to move up and down. Since the rotating ring moves up and down, the auxiliary shaft 332 contracts upward. Due to blood collection tubes of different specifications, the moving distances of the jaws 41 are different, so the upward contraction distances of the auxiliary shaft 332 are also different. The meshing main gear 334 and auxiliary gear 333 are different, so the rotation speeds of the auxiliary shaft 332 are different;
[0055] In the initial state, the insertion rod 3318 on one side of the slide plate 3316 is inserted into the groove 3317 of the mounting plate 3313. During mixing, the main gear 334 rotates, driving the auxiliary gear 333 and the auxiliary shaft 332 to rotate synchronously. The auxiliary shaft 332 drives the lead screw 3319 to rotate through a chain belt. The rotation of the lead screw 3319 drives the slide plate 3316 to move up and down reciprocally. When the slide plate 3316 moves up and down, it can drive the mounting plate 3313 and the rack plate 3314 to move synchronously through the insertion rod 3318, realizing the rotation of the first gear 3312, the jaws 41, and the blood collection tube, that is, realizing the action of mixing the blood and anticoagulant in the blood collection tube;
[0056] The smaller the specification of the blood collection tube, the more switches 3315 triggered by the long rod 337. Through different switches 3315, the contraction of different second telescopic rods is controlled. After the second telescopic rods contract, they can push the corresponding rack plates 3314 to move, so that the corresponding rack plates 3314 are not in the same plane as the first gear 3312. Subsequently, the mounting plate 3313 is controlled to slide up and down. The up and down sliding of the mounting plate 3313 drives the rack plate 3314 to move synchronously. When the rack plate 3314 moves up and down, it drives the first gear 3312 to rotate reciprocally. When the number of up and down reciprocating movements of the mounting plate 3313 remains unchanged, the fewer the rack plates 3314 meshing with the first gear 3312 on the mounting plate 3313, the fewer the number of rotations of the first gear 3312, that is, the fewer the number of rotations of the blood collection tube, to further achieve precise control of blood collection tubes of different specifications;
[0057] After the monitoring component 34 detects that there are air bubbles in the blood collection tube, the control toothed plate 38 is slid downward, so that when the fixed seat 32 drives the rotating ring to rotate to this position, the gear set 39 can be driven to rotate. The rotation of the gear set 39 drives the third rotating ring 35 to rotate. The rotation of the rotating ring causes the knocking rod to reciprocate up and down to knock on the blood collection tube. Through the knocking, the air bubbles rise to the top of the blood collection tube, thereby eliminating the air bubbles, ensuring that the blood sample in the blood collection tube is sufficient and free from air bubble interference, and maintaining the purity of the sample and the accuracy of the detection.
[0058] The control disc 31 rotates. When the disc 31 rotates below the sampling needle 2, the mixing is completed. The sampling needle 2 is controlled to sample the blood collection tube, and the detector body 1 performs detection. After the detection is completed, the control disc 31 continues to rotate to sample and detect the next blood collection tube, that is, the continuous mixing and detection actions of blood collection tubes of multiple specifications are realized.
[0059] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited by the above embodiments. What is described in the above embodiments and the specification only illustrates the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention will have various changes and improvements, and these changes and improvements all fall within the scope of the present invention claimed. The scope of protection claimed by the present invention is defined by the appended claims and their equivalents.
Claims
1. A blood testing device for experimental animals, comprising a detector body (1) and a sampling needle (2), characterized in that: The invention also comprises a sample mixing part (3) for mixing animal blood and anticoagulant, wherein the sample mixing part (3) comprises: Rotating a disk (31) mounted on the detector body (1); A plurality of fixing seats (32) mounted on the disc (31), wherein a clamping assembly (4) is rotatably mounted on the fixing seats (32); A driving assembly (33) is mounted on the fixing seat (32), the driving assembly (33) comprising a main shaft (331) rotatably mounted on the fixing seat (32) and a secondary shaft (332) for driving the clamping assembly (4) to rotate, a plurality of groups of secondary gears (333) and main gears (334) are respectively mounted on the secondary shaft (332) and the main shaft (331), each group of the secondary gears (333) and the main gear (334) having a different tooth ratio, the secondary shaft (332) adopts a telescopic structure, and under the condition that the rotation speed of the main shaft (331) remains unchanged, different groups of secondary gears (333) are meshed with the main gear (334), and the rotation speed of the secondary shaft (332) is different.
2. The blood testing device for experimental animals according to claim 1, characterized in that: The drive assembly (33) further comprises: Rotating a handle (335) mounted on the fixing seat (32), wherein the handle (335) is fixedly mounted on the clamping assembly (4); Rotating a first swivel (336) mounted on the fixing seat (32); A long rod (337) is slidably mounted on the fixing seat (32), the long rod (337) is threadedly connected to the first swivel (336), the clamping assembly (4) comprises a clamping claw (41), and the long rod (337) passes through the handle (335) and is rotatably connected to the clamping claw (41) of the clamping assembly (4); A second swivel (338) is rotatably mounted on the fixing seat (32), and a belt for transmission is installed between the first swivel (336) and the second swivel (338); A pull rod (339) threadedly connected to the second swivel (338); A circular ring (3310) is rotatably mounted on the secondary shaft (332), wherein the circular ring (3310) is located at the movable end of the secondary shaft (332), and a connecting rod (3311) is rotatably connected between the circular ring (3310) and the pull rod (339).
3. The blood testing device for experimental animals according to claim 2, characterized in that: The drive assembly (33) further comprises: A first gear (3312) fixedly mounted on the handle (335); A mounting plate (3313) slidably mounted on the fixing seat (32); a plurality of rack plates (3314) mounted on the mounting plate (3313), wherein the rack plates (3314) are used to drive the first gear (3312) to rotate, and a portion of the rack plates (3314) are slidably connected to the mounting plate (3313); A plurality of switches (3315) are installed in the handle (335), and different switches (3315) are used to control the sliding of different rack plates (3314). The long rod (337) contains a protruding portion for triggering the switch (3315).
4. The blood testing device for experimental animals according to claim 3, characterized in that: The drive assembly (33) further comprises: A slide plate (3316) slidably mounted on the fixing seat (32); A groove (3317) is provided on the mounting plate (3313), and the mounting plate (3313) and the rack plate (3314) include two groups and are symmetrically distributed on both sides of the first gear (3312); Two insertion rods (3318) slidably mounted on the slide plate (3316), the insertion rods (3318) being used in conjunction with the grooves (3317); Rotate a screw rod (3319) mounted on the fixing seat (32), wherein the screw rod (3319) is used to drive the slide plate (3316) to slide up and down, and a chain belt is installed between the screw rod (3319) and the secondary shaft (332), and transmission is carried out through the chain belt; A cam (3320) and a ratchet wheel (3321) are rotatably mounted on the slide plate (3316), wherein the cam (3320) is fixedly connected to the ratchet wheel (3321), and the cam (3320) is used to push the insertion rod (3318) to slide relative to the slide plate (3316), and a spring (3322) is mounted between the insertion rod (3318) and the slide plate (3316); A No. 1 pawl (3323) is used to drive the No. 1 ratchet wheel (3321) to rotate, wherein the No. 1 pawl (3323) is rotatably mounted on the fixing seat (32), and the No. 1 ratchet wheel (3321) is located within the moving range of the No. 1 pawl (3323).
5. The blood testing device for experimental animals according to claim 4, characterized in that: The sample mixing section (3) further comprises a monitoring component (34) mounted on the detector body (1), wherein the monitoring component (34) is used to observe whether hemolysis occurs in the blood in the blood collection tube.
6. The blood testing device for experimental animals according to claim 5, characterized in that: The sample mixing unit (3) further comprises: Rotating a third swivel (35) mounted on the fixing seat (32); A knocking rod (36) is slidably mounted on the fixing seat (32) up and down, a sliding groove is provided on the knocking rod (36), a protrusion is provided on the third rotating ring (35), the protrusion slides in the sliding groove, a second spring (37) is provided between the third rotating ring (35) and the knocking rod (36), and the third rotating ring (35) rotates through the dual action of the protrusion and the second spring (37), driving the knocking rod (36) to knock back and forth up and down; A tooth plate (38) slidably mounted on the detector body (1) up and down; A gear set (39) is used to drive the third rotating ring (35) to rotate, and the gear set (39) is rotatably mounted on the fixing seat (32).
7. The blood testing device for experimental animals according to claim 6, characterized in that: The sample mixing unit (3) further comprises: A round rod (310) mounted on the fixing seat (32); Two third gears (311) rotatably mounted on the round rod (310), the two third gears (311) transmitting one-way therebetween, one of the third gears (311) being meshedly connected with the third rotating ring (35); A second ratchet wheel (312) is rotatably mounted on the fixing seat (32), wherein the second ratchet wheel (312) is meshedly connected with the third gear (311), and a protrusion (313) is provided on the second ratchet wheel (312); A third ratchet wheel (314) is rotatably mounted on the fixing seat (32), a sensor (315) is fixedly mounted on the third ratchet wheel (314), and the sensor (315) is used in conjunction with the protrusion (313); A No. 2 ratchet pawl (316) slidably mounted on the fixing seat (32), the No. 2 ratchet pawl (316) being used to limit the No. 3 ratchet wheel (314) and the No. 2 ratchet wheel (312) from rotating in one direction; A third telescopic rod (317) fixedly mounted on the fixing seat (32), wherein the third telescopic rod (317) is used to drive the second pawl (316) to slide; A third spring (318) mounted on the third ratchet (314), the second ratchet (312) and the fixing seat (32); The fourth gear (319) mounted on the fixing seat (32) is rotated, and the fourth gear (319) is used to drive the third ratchet wheel (314) to rotate.
Citation Information
Patent Citations
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