Bacteriostatic odor-removing soothing pad towel containing wormwood and red ginseng and preparation method of pad towel

Abstract

The invention belongs to the technical field of hygienic products, and particularly relates to a bacteriostatic, odor-removing and soothing pad towel containing wormwood and red ginseng and a preparation method of the pad towel. The pad towel comprises a bacteriostatic odor-removing soothing layer, and the bacteriostatic odor-removing soothing layer is obtained by dipping all-cotton spunlace non-woven fabric in amino cyclodextrin mixed liquor containing wormwood and red ginseng and drying the all-cotton spunlace non-woven fabric. The antibacterial, odor-removing and soothing pad towel containing the wormwood and the red ginseng has excellent antibacterial property, storage stability and no irritation, and can also remove peculiar smell.

Description

Technical Field

[0001] The present invention belongs to the technical field of sanitary products, and particularly relates to a pad containing mugwort and red ginseng with bacteriostatic, odor-removing and soothing functions and a preparation method thereof. Background Art

[0002] During a woman's menstrual period, in order to avoid soiling clothes with menstrual blood and keep the body clean, sanitary products are essential. Traditional sanitary products mainly focus on absorption performance and leak-proof design. With the improvement of people's living standards and health awareness, more and more people pay attention to the functionality of sanitary products. During menstruation, menstrual blood is stored in sanitary products. Due to the humid environment and temperature of menstrual blood in sanitary products, bacteria are extremely likely to be produced, resulting in odors. In addition, the uterus is prone to contract during menstruation, causing pain. Therefore, it is necessary to develop sanitary products with bacteriostatic, odor-removing and soothing functions.

[0003] Chinese Patent with Publication No. CN107485729A discloses an artemisia argyi herb care sanitary napkin chip and a sanitary napkin. The mixture used for the sanitary napkin chip includes the following raw materials in parts by weight: 30-50 parts of artemisia argyi extract, 10-30 parts of motherwort extract, 5-15 parts of cnidium monnieri extract, 10-20 parts of far-infrared nano powder, 10-20 parts of nano zinc powder, and 150-200 parts of deionized water. The artemisia argyi herb care sanitary napkin chip of this technical solution makes full use of the action advantages and mutual synergistic effects of components such as artemisia argyi extract, motherwort extract, cnidium monnieri extract, far-infrared nano powder and nano zinc powder. When the prepared sanitary napkin chip is applied to a sanitary napkin, it has functions such as promoting qi and blood circulation, warming the meridians and dispelling cold, bacteriostasis, removing odors, regulating dysmenorrhea, relieving discomfort, soothing emotions and calming the nerves. However, this technical solution directly immerses non-woven fabric in a mixture of drug extracts and then dries it for preparation, and the adhesion time of active ingredients on the non-woven fabric is limited.

[0004] A Chinese patent with the publication number CN106729937A discloses a plateau Chinese herbal medicine sanitary napkin. The Chinese herbal medicine formula it contains is made up of the following components by weight: 200-300 parts of snow lotus, 200-300 parts of astragalus membranaceus, 300-400 parts of pearl, 250-350 parts of aloe vera, 250-350 parts of chuanxiong rhizome, 300-400 parts of angelica sinensis, 250-350 parts of cyperus rotundus, 200-300 parts of red ginseng, 350-500 parts of mugwort, 200-300 parts of stemona root, 300-400 parts of cnidium monnieri, 250-350 parts of phellodendron amurense, 200-300 parts of liquorice root, 200-300 parts of honeysuckle flower, 200-300 parts of coptis chinensis, 250-350 parts of sophora flavescens, 200-300 parts of white peony root and 350-500 parts of motherwort. The plateau Chinese herbal medicine sanitary napkin of this technical solution has the effects of activating blood circulation to regulate menstruation, anti-inflammatory and analgesic, warming the uterus and removing stasis, antibacterial and detoxifying, enriching blood and strengthening vital energy, removing peculiar smell, dispelling dampness and cold, warming the meridian and dredging collaterals, relieving itching and expelling toxins, etc. However, this technical solution contains up to 18 kinds of Chinese herbal medicines, and the cost is relatively high. Summary of the Invention

[0005] Based on the defects existing in the prior art, the purpose of the present invention is to provide a bacteriostatic, odor-removing and soothing pad containing mugwort and red ginseng and its preparation method. The bacteriostatic, odor-removing and soothing pad containing mugwort and red ginseng of the present invention has excellent antibacterial properties, storage stability and non-irritation, and can also remove peculiar smell.

[0006] To achieve the above purpose, the technical solution adopted by the present invention is as follows:

[0007] The first aspect of the present invention provides a bacteriostatic, odor-removing and soothing pad containing mugwort and red ginseng, including a bacteriostatic, odor-removing and soothing layer, which is obtained by impregnating a cotton spunlace non-woven fabric in a mixed solution of amino cyclodextrin containing mugwort and red ginseng and drying.

[0008] Preferably, the amino cyclodextrin is zeolite powder-modified amino cyclodextrin.

[0009] Preferably, the zeolite powder-modified amino cyclodextrin is obtained by mixing zeolite powder, amino cyclodextrin and water evenly, stirring, filtering, washing and drying.

[0010] In the field of traditional Chinese medicine, cyclodextrin is often used to encapsulate traditional Chinese medicine extracts to prevent the inactivation of active ingredients in traditional Chinese medicine extracts. However, the inventor found during the experiment that the sanitary pads obtained by only using cyclodextrin to encapsulate the volatile oil and extracts prepared in the present invention showed mildew after accelerated experiments (which can judge whether the storage period of the sanitary pads is set to 3 years), and the antibacterial rates against Staphylococcus aureus, Candida albicans, and Escherichia coli were all lower than 90%, that is, unqualified. This phenomenon may be because the extracts prepared in the present invention contain some macromolecular polysaccharides, and cyclodextrin encapsulates them incompletely, resulting in their degradation and deterioration; the present invention utilizes the electrostatic interaction between zeolite powder and cyclodextrin to modify cyclodextrin with zeolite powder. Surprisingly, it was found that after the accelerated stability experiment of the sanitary pads obtained by using carboxymethyl-β-cyclodextrin, the inhibitory rate against Candida albicans was lower than 90%, that is, unqualified, while the use of amino cyclodextrin was qualified. This phenomenon may be on the one hand because both carboxymethyl-β-cyclodextrin and zeolite powder carry negative charges and cannot form a complex, resulting in poor coating effect on the volatile oil and extracts of the present invention, and on the other hand because the hydrophilicity of carboxymethyl-β-cyclodextrin is significantly higher than that of amino cyclodextrin, which may accelerate the release of active ingredients in the inclusion complex.

[0011] Further preferably, the zeolite powder modified amino cyclodextrin: Mix zeolite powder, amino cyclodextrin and water evenly, stir at 20 - 30 °C and 200 - 500 rpm for 2 - 3 h, filter, wash, and dry to obtain zeolite powder modified amino cyclodextrin.

[0012] Further preferably, the mass ratio of the zeolite powder, amino cyclodextrin and water is 0.1:1 - 2:10 - 20.

[0013] Further preferably, the amino cyclodextrin is amino-β-cyclodextrin.

[0014] Further preferably, the amino-β-cyclodextrin includes mono-6-deoxy-amino-β-cyclodextrin and / or mono-6-deoxy-ethylenediamine-β-cyclodextrin.

[0015] Preferably, the preparation method of the amino cyclodextrin containing wormwood and red ginseng:

[0016] S1. Crush wormwood and red ginseng, add water and arylimidazolium ionic liquid, perform distillation extraction, and collect volatile oil, filtrate A and residue A;

[0017] S2. Mix residue A and extraction solvent, perform ultrasonic extraction to obtain filtrate B and residue B;

[0018] S3. Mix filtrate A and filtrate B, adsorb and elute with macroporous adsorption resin, collect the eluate, concentrate and dry to obtain the extract;

[0019] S4. Mix amino-cyclodextrin, volatile oil and water evenly, and stir to obtain inclusion complex A;

[0020] S5. Mix amino-cyclodextrin, extract and water evenly, and stir to obtain inclusion complex B;

[0021] S6. Mix inclusion complex A and inclusion complex B to obtain amino-cyclodextrin containing Artemisia argyi and red ginseng.

[0022] Artemisia argyi (scientific name: Artemisia argyi H. Lév. & Vaniot): It is a plant of the Compositae family and Artemisia genus. Its chemical components are mainly divided into three categories: volatile oils, flavonoids, and polysaccharides. There are significant differences in the chemical components of Artemisia argyi from different species, origins, and extraction methods.

[0023] Preferably, the Artemisia argyi is Absinthium.

[0024] Red ginseng (Ginseng Radix et Rhizoma Rubra, GRRR) is the cooked product of the plant Panax ginseng C. A. Mey. of the Araliaceae family. Its chemical components are mainly saponins, volatile oils, sugars, amino acids, maltol and its glucosides, etc.; there are significant differences in the chemical components of red ginseng from different origins and extraction methods.

[0025] Preferably, the red ginseng is Korean red ginseng.

[0026] Ionic liquids have been frequently used in traditional Chinese medicine extraction schemes. However, due to the differences in the active ingredients of traditional Chinese medicine and the active ingredients to be extracted, it is impossible to predict what effects can be achieved by using ionic liquids to extract traditional Chinese medicine. In the experimental process of the present invention, it was unexpectedly found that when using arylimidazole ionic liquids, the pads obtained have a higher antibacterial effect compared to 1-butyl-3-methylimidazolium hexafluorophosphate, and the results of the vaginal mucosa irritation test show no irritation. The reason for this phenomenon may be that arylimidazole ionic liquids can bind to the active ingredients containing aryl groups in Artemisia argyi and red ginseng through π-π interactions, improving the extraction rate of the active ingredients; at the same time, arylimidazole ionic liquids themselves have low irritation and low residue levels in the pads during extraction, thereby reducing the potential irritation of long-term contact.

[0027] After extracting the volatile oils from Artemisia argyi and Panax ginseng, the residue is further extracted. By adding a small amount of surfactant to improve the extraction effect, it is found that the antibacterial performance of the sanitary napkin obtained by extraction using caprylyl / capramidopropyl betaine and sodium cocoyl amphoacetate is better. When using caprylyl / capramidopropyl betaine and laureth, after the accelerated experiment, not only does the antibacterial performance deteriorate significantly, but also mildew appears. The reason for this phenomenon may be that the long-chain alkyl group of laureth may disrupt the combination of the active ingredients in the residue and the solvent, resulting in a decrease in the dissolution rate of the active ingredients and a decrease in the active ingredients that inhibit molds.

[0028] Preferably, the arylimidazolium ionic liquid is selected from at least one of 1-benzyl-3-methylimidazolium chloride, 1-benzyl-3-methylimidazolium bromide, 1-benzyl-3-methylimidazolium tetrafluoroborate, and 1-benzyl-3-methylimidazolium hexafluorophosphate.

[0029] Preferably, the mass ratio of the Artemisia argyi, Panax ginseng, water, and arylimidazolium ionic liquid is 6-10:1:70-110:0.3-0.6.

[0030] Preferably, in step S1, the temperature of the distillation extraction is 70-90 °C, and the time of the distillation extraction is 1-2 h.

[0031] Preferably, the extraction solvent includes water, ethanol, caprylyl / capramidopropyl betaine, and sodium cocoyl amphoacetate.

[0032] Preferably, the mass ratio of the water, ethanol, caprylyl / capramidopropyl betaine, and sodium cocoyl amphoacetate is 20-30:69-79:0.8-0.9:0.1-0.2.

[0033] Preferably, the mass ratio of the residue A and the extraction solvent is 1:8-12.

[0034] Preferably, in step S2, the temperature of the ultrasonic extraction is 40-60 °C, and the time of the ultrasonic extraction is 1-2 h.

[0035] Preferably, step S3 is specifically: mixing filtrate A and filtrate B, adsorbing with macroporous adsorption resin D101, eluting with a methanol aqueous solution, collecting the eluate, concentrating and drying to obtain the extract.

[0036] Preferably, the elution in step S3 is specifically: eluting with a methanol aqueous solution with a volume fraction of 40-60% and a volume of 3-6 times the column volume.

[0037] Preferably, the mass ratio of the aminocyclodextrin, volatile oil, and water is 1:5-8:3-5.

[0038] Preferably, the temperature of the stirring in step S4 is 50-70°C, the stirring time is 1-3 h, and the stirring speed is 200-400 rpm.

[0039] Preferably, the mass ratio of the aminocyclodextrin, the extract, and water is 1:3-5:3-5.

[0040] Preferably, the temperature of the stirring in step S5 is 50-70°C, the stirring time is 1-3 h, and the stirring speed is 200-400 rpm.

[0041] Preferably, the antibacterial, odor-removing, and soothing pad towel containing mugwort and red ginseng further comprises a cotton soft layer, a water-absorbing layer, a bottom layer, and a release paper.

[0042] More preferably, the antibacterial, odor-removing, and soothing pad towel containing mugwort and red ginseng sequentially comprises a cotton soft layer, an antibacterial, odor-removing, and soothing layer, a water-absorbing layer, a bottom layer, and a release paper.

[0043] The present invention does not make specific limitations on the cotton soft layer, the water-absorbing layer, the bottom layer, and the release paper. Conventional cotton soft layers, water-absorbing layers, bottom layers, and release papers in the art can all achieve the solutions and effects of the present invention.

[0044] The second aspect of the present invention provides a preparation method of the above-mentioned antibacterial, odor-removing, and soothing pad towel containing mugwort and red ginseng: dipping the cotton hydrospun non-woven fabric in the aminocyclodextrin mixed solution containing mugwort and red ginseng, and drying to obtain the antibacterial, odor-removing, and soothing layer; sequentially laminating the cotton soft layer, the antibacterial, odor-removing, and soothing layer, the water-absorbing layer, the bottom layer, and the release paper to obtain the product.

[0045] Preferably, the aminocyclodextrin mixed solution containing mugwort and red ginseng is obtained by uniformly mixing aminocyclodextrin containing mugwort and red ginseng and water.

[0046] Preferably, the mass ratio of the aminocyclodextrin containing mugwort and red ginseng to water is 0.5-2:10.

[0047] Preferably, the temperature of the dipping is 25-30°C, and the dipping time is 20-40 min.

[0048] Compared with the prior art, the present invention has the following beneficial effects:

[0049] The antibacterial, odor-removing, and soothing pad towel containing mugwort and red ginseng provided by the present invention uses the volatile oil and extract obtained by a specific extraction solvent, which are effectively included in the zeolite powder-modified aminocyclodextrin. The pad towel not only has excellent antibacterial performance, but also has a storage period of 3 years, no mildew phenomenon, no irritation, and the existing zeolite powder-modified aminocyclodextrin can also adsorb odors. Detailed Embodiments

[0050] In order to have a clearer understanding of the technical features, purposes and effects of the present invention, a specific implementation scheme is now described in detail.

[0051] The present invention is further described below in conjunction with the examples, but the present invention is not limited to the following examples. The implementation conditions used in the examples can be further adjusted according to the different requirements of specific use, and the implementation conditions not specified are conventional conditions in the industry. The technical features involved in each embodiment of the present invention can be combined with each other as long as they do not conflict with each other.

[0052] In the following examples and comparative examples, unless otherwise specified, all raw materials used were commercially available or prepared by conventional methods in the art.

[0053] The raw material information used in the following examples and comparative examples:

[0054] Zeolite powder was purchased from Chaoyang Xinhe Zeolite Technology Co., Ltd., specification: 1500 mesh;

[0055] Mono-6-deoxy-amino-β-cyclodextrin was purchased from Xi'an Qiyue Biotechnology Co., Ltd.;

[0056] Carboxymethyl-β-cyclodextrin was purchased from Shanghai Yuanye Biotechnology Co., Ltd.;

[0057] 1-Benzyl-3-methylimidazolium chloride was purchased from Qingdao Aolike New Material Technology Co., Ltd.;

[0058] 1-Butyl-3-methylimidazolium hexafluorophosphate was purchased from Qingdao Aolike New Material Technology Co., Ltd.;

[0059] Caprylic decanoylaminopropyl betaine was purchased from Guangzhou Zhonghai Chemical Co., Ltd., specification: Betain 810; and sodium cocoamphoacetate;

[0060] Sodium lauroamphoacetate was purchased from Guangzhou Zhonghai Chemical Co., Ltd., specification: SCA-35;

[0061] Lauryl alcohol polyoxyethylene ether was purchased from Zhejiang Jinguang Industrial Co., Ltd., model: AEO-5;

[0062] The soft surface layer is hot air polylactic acid nonwoven fabric, purchased from Yisheng New Materials (Suzhou) Co., Ltd.;

[0063] The 100% cotton spunlace nonwoven fabric was purchased from Anqing Huaxin Industrial Fabric Co., Ltd.;

[0064] The water-absorbing layer is a mesh non-woven fabric purchased from Fujian Jianwei Medical Supplies Co., Ltd.

[0065] The bottom layer is a base film, which was purchased from Fujian Green Grid New Material Technology Co., Ltd.

[0066] Preparation Example 1 Preparation of zeolite powder modified amino-cyclodextrin A:

[0067] The zeolite powder, mono-6-deoxy-amino-β-cyclodextrin and water were mixed evenly, stirred at 30 °C and 300 rpm for 2.5 h, filtered, washed, and dried to obtain zeolite powder modified amino-cyclodextrin A.

[0068] The mass ratio of the zeolite powder, mono-6-deoxy-amino-β-cyclodextrin and water was 0.1:1.5:15.

[0069] Preparation Example 2 Preparation of zeolite powder modified carboxymethyl-β-cyclodextrin:

[0070] The zeolite powder, carboxymethyl-β-cyclodextrin and water were mixed evenly, stirred at 30 °C and 300 rpm for 2.5 h, filtered, washed, and dried to obtain zeolite powder modified carboxymethyl-β-cyclodextrin.

[0071] The mass ratio of the zeolite powder, carboxymethyl-β-cyclodextrin and water was 0.1:1.5:15.

[0072] Preparation Example 3 Preparation of amino-cyclodextrin A containing Artemisia argyi and red ginseng:

[0073] S1. Artemisia argyi and Korean red ginseng were pulverized, water and 1-benzyl-3-methylimidazolium chloride were added, and steam distillation extraction was carried out to collect the volatile oil, filtrate A and residue A;

[0074] The mass ratio of Artemisia argyi, Korean red ginseng, water and 1-benzyl-3-methylimidazolium chloride was 8:1:90:0.5;

[0075] In step S1, the temperature of the steam distillation extraction was 80 °C and the time of the steam distillation extraction was 2 h;

[0076] S2. The residue A and the extraction solvent were mixed and subjected to ultrasonic extraction to obtain filtrate B and residue B;

[0077] The extraction solvent included water, ethanol, caprylic / capric amide propyl betaine and cocoyl amphoacetate sodium;

[0078] The mass ratio of water, ethanol, caprylic / capric amide propyl betaine and cocoyl amphoacetate sodium was 25:74:0.8:0.2;

[0079] The mass ratio of the residue A and the extraction solvent was 1:10;

[0080] In step S2, the temperature of the ultrasonic extraction was 50 °C and the time of the ultrasonic extraction was 2 h;

[0081] S3. Filtrate A and filtrate B were mixed, adsorbed with macroporous adsorption resin D101, eluted with a methanol aqueous solution, the eluate was collected, concentrated and dried to obtain an extract;

[0082] The elution described in step S3 is specifically as follows: elute with a methanol aqueous solution with a volume fraction of 50% and a volume 5 times that of the column volume;

[0083] S4. Mix zeolite powder modified aminocyclodextrin A, volatile oil and water evenly, and stir to obtain inclusion complex A;

[0084] The mass ratio of the zeolite powder modified aminocyclodextrin A, volatile oil and water is 1:6:5;

[0085] The temperature of the stirring described in step S4 is 60°C, the stirring time is 2 h, and the stirring speed is 300 rpm;

[0086] S5. Mix zeolite powder modified aminocyclodextrin A, extract and water evenly, and stir to obtain inclusion complex B;

[0087] The mass ratio of the zeolite powder modified aminocyclodextrin A, extract and water is 1:4:4;

[0088] The temperature of the stirring described in step S5 is 60°C, the stirring time is 2 h, and the stirring speed is 300 rpm;

[0089] S6. Mix inclusion complex A and inclusion complex B to obtain aminocyclodextrin A containing wormwood and red ginseng.

[0090] Preparation Example 4 prepares carboxymethyl-β-cyclodextrin containing wormwood and red ginseng:

[0091] The difference from Preparation Example 4 is only that the zeolite powder modified aminocyclodextrin A is replaced with zeolite powder modified carboxymethyl-β-cyclodextrin of the same mass, and the rest are the same.

[0092] Preparation Example 5 prepares aminocyclodextrin B containing wormwood and red ginseng:

[0093] The difference from Preparation Example 4 is only that the zeolite powder modified aminocyclodextrin A is replaced with single-6-deoxy-amino-β-cyclodextrin of the same mass, and the rest are the same.

[0094] Preparation Example 6 prepares aminocyclodextrin C containing wormwood and red ginseng:

[0095] The difference from Preparation Example 4 is only that 1-benzyl-3-methylimidazolium chloride is replaced with 1-butyl-3-methylimidazolium hexafluorophosphate of the same mass; the rest are the same.

[0096] Preparation Example 7 prepares aminocyclodextrin D containing wormwood and red ginseng:

[0097] The difference from Preparation Example 4 is only that cocamidopropyl betaine is replaced with lauryl polyoxyethylene ether of the same mass; the rest are the same.

[0098] Preparation Example 8 Preparation of Artemisia argyi-containing aminocyclodextrin:

[0099] The difference from Preparation Example 4 is only that the Korean red ginseng is replaced with the same mass of Artemisia absinthium; the rest are the same.

[0100] Preparation Example 9 Preparation of red ginseng-containing aminocyclodextrin:

[0101] The difference from Preparation Example 4 is only that the Artemisia absinthium is replaced with the same mass of Korean red ginseng; the rest are the same.

[0102] Example 1 Preparation of antibacterial, odor-removing and soothing sanitary napkin A containing Artemisia argyi and red ginseng:

[0103] The all-cotton hydrospun non-woven fabric is impregnated in the mixed solution of aminocyclodextrin A containing Artemisia argyi and red ginseng, and dried to obtain the antibacterial, odor-removing and soothing layer; the cotton soft layer, the antibacterial, odor-removing and soothing layer, the water-absorbing layer, the bottom layer and the release paper are sequentially compounded with hot melt adhesive to obtain.

[0104] The mixed solution of aminocyclodextrin A containing Artemisia argyi and red ginseng: It is obtained by uniformly mixing aminocyclodextrin A containing Artemisia argyi and red ginseng and water.

[0105] The mass ratio of the aminocyclodextrin A containing Artemisia argyi and red ginseng to water is 1:10.

[0106] The temperature of the impregnation is 25 °C, and the time of the impregnation is 30 min.

[0107] Example 2 Preparation of antibacterial, odor-removing and soothing sanitary napkin B containing Artemisia argyi and red ginseng:

[0108] The difference from Example 1 is only that the aminocyclodextrin A containing Artemisia argyi and red ginseng is replaced with the same mass of carboxymethyl-β-cyclodextrin containing Artemisia argyi and red ginseng; the rest are the same.

[0109] Example 3 Preparation of antibacterial, odor-removing and soothing sanitary napkin C containing Artemisia argyi and red ginseng:

[0110] The difference from Example 1 is only that the aminocyclodextrin A containing Artemisia argyi and red ginseng is replaced with the same mass of aminocyclodextrin B containing Artemisia argyi and red ginseng; the rest are the same.

[0111] Example 4 Preparation of antibacterial, odor-removing and soothing sanitary napkin D containing Artemisia argyi and red ginseng:

[0112] The difference from Example 1 is only that the aminocyclodextrin A containing Artemisia argyi and red ginseng is replaced with the same mass of aminocyclodextrin C containing Artemisia argyi and red ginseng; the rest are the same.

[0113] Example 5 Preparation of antibacterial, odor-removing and soothing sanitary napkin E containing Artemisia argyi and red ginseng:

[0114] The difference from Example 1 is only that the amino-cyclodextrin A containing mugwort and red ginseng is replaced with the amino-cyclodextrin D containing mugwort and red ginseng of the same mass; the rest are the same.

[0115] Example 6 Preparation of a bacteriostatic, odor-removing and soothing sanitary napkin containing mugwort

[0116] The difference from Example 1 is only that the amino-cyclodextrin A containing mugwort and red ginseng is replaced with the amino-cyclodextrin containing mugwort of the same mass; the rest are the same.

[0117] Example 7 Preparation of a bacteriostatic, odor-removing and soothing sanitary napkin containing red ginseng

[0118] The difference from Example 1 is only that the amino-cyclodextrin A containing mugwort and red ginseng is replaced with the amino-cyclodextrin containing red ginseng of the same mass; the rest are the same.

[0119] Effect verification was carried out on the sanitary napkins prepared in Examples 1-7:

[0120] (1) Antibacterial property: Conducted according to the method for testing the antibacterial performance of dissolving antibacterial (bacteriostatic) products in Appendix C-C4 of GB / T 15979-2024 "Hygiene Standards for Disposable Sanitary Products".

[0121] (2) Vaginal mucosa irritation test: Conducted according to the vaginal mucosa irritation test in Part 2.3.5 of the "Disinfection Technical Specification" (2002 Edition).

[0122] Experimental animals: Healthy, newly adult female white rabbits of the same strain, weighing 2.0 - 2.5 kg. 3 rabbits were selected for the experiment in each example and control group.

[0123] Experimental samples: The surface layer samples of the sanitary napkin were cut into appropriate sizes and operated under sterile conditions.

[0124] The method of dosing for a single vaginal mucosa irritation test: Fix the rabbit on its back and expose the perineum and vaginal orifice. Make the test substance fully contact with the vaginal mucosa to complete the dosing. The control group animals were treated in the same way with physiological saline.

[0125] Observation and record: 24 hours after dosing, the rabbits were sacrificed, the vaginal tissues were taken out, and phenomena such as mucosal degeneration, secretion, vascular congestion, and edema were carefully observed with the naked eye. If there were changes, histological examination was performed.

[0126] (3) Accelerated stability: The samples were placed in an incubator at 40 - 45 °C for 180 days, and it was observed whether mildew occurred and the bacteriostatic rate was tested.

[0127] The test results are shown in Table 1:

[0128] Table 1

[0129]

[0130] As can be seen from Table 1, in Example 6 and Example 7, only Artemisia argyi or only Panax ginseng was used, and the initial antibacterial property and antibacterial property after the accelerated experiment of the obtained sanitary pads were far inferior to those obtained by using both Artemisia argyi and Panax ginseng; mildew appeared after the accelerated experiment in Example 6; in Example 2, single-6-deoxy-amino-β-cyclodextrin was replaced with carboxymethyl-β-cyclodextrin, and the inhibition rate of Candida albicans of the obtained sanitary pad after the accelerated experiment was lower than 90%; in Example 3, zeolite powder modified amino cyclodextrin was replaced with single-6-deoxy-amino-β-cyclodextrin, mildew appeared after the accelerated experiment of the obtained sanitary pad, and the inhibition rates of Staphylococcus aureus, Candida albicans, and Escherichia coli were all lower than 90%; in Example 4, 1-benzyl-3-methylimidazolium chloride was replaced with 1-butyl-3-methylimidazolium hexafluorophosphate of the same mass, the initial antibacterial property of the obtained sanitary pad not only decreased, but also had mild irritation, and mildew appeared after the accelerated experiment; in Example 5, cocamidopropyl betaine was replaced with lauryl polyoxyethylene ether of the same mass, the initial antibacterial property of the obtained sanitary pad not only decreased, but also mildew appeared after the accelerated experiment.

[0131] Finally, it should be noted that the above content is only used to illustrate the technical solution of the present invention, rather than a limitation on the protection scope of the present invention. Any simple modification or equivalent replacement made by those of ordinary skill in the art to the technical solution of the present invention does not depart from the essence and scope of the technical solution of the present invention.

Claims

1. A bacteriostatic, deodorizing and soothing towel containing mugwort and red ginseng, characterized in that: The invention comprises an antibacterial and deodorizing soothing layer, which is obtained by dipping all-cotton spunlace non-woven fabric into an aminocyclodextrin mixed liquid containing wormwood and red ginseng and then drying the mixed liquid.

2. The antibacterial, deodorizing and soothing towel containing mugwort and red ginseng according to claim 1, characterized in that: The aminocyclodextrin is zeolite powder modified aminocyclodextrin.

3. The antibacterial, deodorizing and soothing towel containing mugwort and red ginseng according to claim 2, characterized in that: The zeolite powder modified aminocyclodextrin comprises the following steps: zeolite powder, aminocyclodextrin and water are uniformly mixed, stirred, filtered, washed and dried to obtain zeolite powder modified aminocyclodextrin.

4. The antibacterial, deodorizing and soothing towel containing mugwort and red ginseng according to claim 3, characterized in that: The aminocyclodextrin is aminoβ-cyclodextrin; the aminoβ-cyclodextrin includes mono-6-deoxy-amino-β-cyclodextrin and / or mono-6-deoxy-ethylenediamine-β-cyclodextrin.

5. The antibacterial, deodorizing and soothing towel containing mugwort and red ginseng according to claim 4, characterized in that: The preparation method of the aminocyclodextrin containing wormwood and red ginseng: S1, crushing mugwort and red ginseng, adding water and aryl imidazole type ionic liquid, distilling and extracting, collecting volatile oil, filtrate A and residue A; S2, the filter residue A is mixed with the extraction solvent, and ultrasonic extraction is performed to obtain filtrate B and filter residue B; S3, filtrate A and filtrate B are mixed, adsorbed and eluted by macroporous adsorption resin, and the eluate is collected, concentrated and dried to obtain an extract; S4, aminocyclodextrin, volatile oil and water are mixed evenly and stirred to obtain inclusion compound A; S5, aminocyclodextrin, the extract and water are mixed evenly and stirred to obtain inclusion compound B; S6. The inclusion compound A and the inclusion compound B are mixed to obtain aminocyclodextrin containing mugwort and red ginseng.

6. The antibacterial, deodorizing and soothing towel containing mugwort and red ginseng according to claim 5, characterized in that: The mugwort is wormwood; and the red ginseng is Korean red ginseng.

7. The antibacterial, deodorizing and soothing towel containing mugwort and red ginseng according to claim 6, characterized in that: The aromatic imidazolium type ionic liquid is selected from at least one of 1-benzyl-3-methylimidazolium chloride, 1-benzyl-3-methylimidazolium bromide, 1-benzyl-3-methylimidazolium tetrafluoroborate and 1-benzyl-3-methylimidazolium hexafluorophosphate.

8. The antibacterial, deodorizing and soothing towel containing mugwort and red ginseng according to claim 7, characterized in that: The extraction solvent includes water, ethanol, caprylic decanoyl propyl betaine and sodium cocoamphoacetate.

9. The antibacterial, deodorizing and soothing towel containing mugwort and red ginseng according to claim 1, characterized in that: The antibacterial, deodorizing and soothing towel containing mugwort and red ginseng also includes a soft cotton layer, a water-absorbing layer, a bottom layer and release paper.

10. The method for preparing the antibacterial, deodorizing and soothing towel containing mugwort and red ginseng according to claim 9, characterized in that: The following steps are involved: The all-cotton spunlace nonwoven fabric is immersed in an aminocyclodextrin mixture containing mugwort and red ginseng, and dried to obtain an antibacterial and deodorizing soothing layer; the cotton soft layer, the antibacterial and deodorizing soothing layer, the water-absorbing layer, the bottom layer and the release paper are compounded in sequence to obtain the product.

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