Lavender essential oil electrostatic spinning mask as well as preparation method, use method and application thereof

Abstract

The invention belongs to the technical field of cosmetics, and provides a lavender essential oil electrostatic spinning mask as well as a preparation method, a use method and application thereof. The preparation method comprises the following steps: mixing lavender essential oil, propylene glycol, polyvinyl alcohol and water to form a spinning solution; and carrying out electrostatic spinning on the spinning solution to obtain the lavender essential oil electrostatic spinning mask. In a spinning solution, based on the volume of water, the mass fraction of polyvinyl alcohol is 7-9%, the mass fraction of propylene glycol is 4-6%, and lavender essential oil accounts for 0-20% of the mass of propylene glycol and is not 0%; the loading capacity of the lavender essential oil in the electrostatic spinning mask is greatly improved. By controlling parameters of electrostatic spinning, the obtained nanofibers have great specific surface area and excellent porosity, so that the specific surface area and porosity of the electrostatic spinning mask are improved, the loading capacity of the active substance lavender essential oil is improved, and the hydrophilicity of the electrostatic spinning mask is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of cosmetics, and particularly relates to a lavender essential oil electrospun mask and its preparation method, usage method and application. Background Art

[0002] In recent years, sheet masks have been deeply loved by consumers as a kind of skin care product. The types and formulas of the essence of sheet masks are more diverse. It has the functions of softening the cutin layer, preventing water evaporation, accelerating the penetration and absorption of nutrients, etc. The traditional mask formula has complex ingredients and requires many auxiliaries other than the functional ingredients to assist in achieving the effects, and these additives will cause problems such as inflammation and allergies. In order to compete in the mask market, each mask brand is constantly innovating the sheet mask. However, the development of sheet masks has approached saturation, and it will also bring negative impacts such as the harm of preservatives and other additives to the human body, waste of resources, and plastic pollution. The common masks in life are mainly sheet masks containing liquid essence, but this traditional type of mask has various problems such as low water absorption and retention rate, waste of essence, and serious homogenization. The emergence of electrospun masks can fundamentally solve the existing problems of sheet masks and has great development prospects.

[0003] The electrospun mask is a dry film, and when in use, it needs to be used in combination with an aqueous phase. The dry film is sprayed wet with the aqueous phase and then applied. However, the existing electrospun masks have poor hydrophilicity, and after being sprayed wet with the aqueous phase, the adhesion to the skin is poor, which limits their development and application. Summary of the Invention

[0004] In view of this, the purpose of the present invention is to provide a lavender essential oil electrospun mask and its preparation method, usage method and application. The lavender essential oil electrospun mask prepared by the preparation method provided by the present invention has good hydrophilicity.

[0005] In order to achieve the above-mentioned invention purpose, the present invention provides the following technical solutions:

[0006] The present invention provides a preparation method of a lavender essential oil electrospun mask, comprising the following steps:

[0007] Mix lavender essential oil, propylene glycol, polyvinyl alcohol and water to form a spinning solution;

[0008] Perform electrospinning on the spinning solution to obtain the lavender essential oil electrospun mask;

[0009] In the spinning solution, based on the volume of water, the mass fraction of polyvinyl alcohol is 7-9%, the mass fraction of propylene glycol is 4-6%, and the lavender essential oil accounts for 0%-20% of the mass of the propylene glycol, not 0%;

[0010] The parameters of the electrospinning include: the voltage is 15 - 20 kV, the receiving distance is 16 cm, the injection speed is 0.04 - 0.07 mm / min, the receiving speed is 140 r / min, and the translation speed is 200 mm / min.

[0011] Preferably, the mixing of the lavender essential oil, propylene glycol, polyvinyl alcohol and water includes the following steps: firstly mixing the lavender essential oil and propylene glycol to obtain an oil phase; secondly mixing the polyvinyl alcohol and water to obtain an aqueous phase; and thirdly mixing the oil phase and the aqueous phase.

[0012] Preferably, the temperature of the first mixing is 75 - 85 °C and the time is 1 - 3 h; the temperature of the second mixing is 75 - 85 °C and the time is 3 - 5 h; the temperature of the third mixing is 75 - 85 °C and the time is 10 - 50 min.

[0013] Preferably, the parameters of the electrospinning further include: the needle number is 22.

[0014] Preferably, the environmental parameters of the electrospinning include: the spinning temperature is 30 ± 3 °C and the spinning humidity is 25 ± 5%.

[0015] The present invention also provides a lavender essential oil electrospun mask prepared by the preparation method described in the above technical solution.

[0016] Preferably, the lavender essential oil electrospun mask is used in combination with an aqueous phase; the aqueous phase is water.

[0017] The present invention also provides a method for using the lavender essential oil electrospun mask described in the above technical solution, including the following steps:

[0018] Spray the lavender essential oil electrospun mask with the aqueous phase and then use it.

[0019] Preferably, the aqueous phase is water.

[0020] The present invention also provides an application of the lavender essential oil electrospun mask described in the above technical solution in the field of skin care.

[0021] The present invention provides a preparation method of a lavender essential oil electrospun mask.

[0022] 1. The preparation method provided by the present invention uses polyvinyl alcohol as a carrier and water as a solvent to encapsulate lavender essential oil to prepare an electrospun mask. In the spinning solution controlled by the present invention, based on the volume of water, the mass fraction of polyvinyl alcohol is 7-9%, the mass fraction of propylene glycol is 4-6%, and the lavender essential oil accounts for 0%-20% of the mass of propylene glycol, not 0%; this greatly improves the loading amount of lavender essential oil in the electrospun mask. In addition, the parameters of electrospinning controlled by the present invention include: the voltage is 15-20 kV, the receiving distance is 16 cm, the injection speed is 0.04-0.07 mm / min, the receiving speed is 140 r / min, and the translation speed is 200 mm / min, so that the obtained nanofibers have a large specific surface area and excellent porosity, thereby improving the specific surface area and porosity of the electrospun mask, and also being beneficial to improving the loading amount of the active substance lavender essential oil and giving full play to its role.

[0023] 2. Lavender essential oil is highly volatile, which easily leads to the loss of active ingredients. In the present invention, through electrospinning, the physical encapsulation of the essential oil is realized by using the three-dimensional network structure formed by polyvinyl alcohol nanofibers. The fiber diameter is controlled at 311.17±13.10 nm to form a dense carrier system with high porosity. The nanofibers anchor the essential oil molecules inside the fibers through surface adsorption and intermolecular forces (such as van der Waals forces and hydrogen bonds), effectively isolating oxygen and external environmental interference and reducing the evaporation rate of lavender essential oil. In addition, when the obtained electrospun mask contacts water, as the fibers gradually swell, the internal lavender essential oil is continuously released through the pores, avoiding the active loss caused by a one-time excessive release.

[0024] 3. Polyvinyl alcohol and lavender essential oil are hydrophilic, making the electrospun mask easily soluble in water; moreover, the high loading amount of lavender essential oil further improves the hydrophilicity of the electrospun mask and makes it more easily soluble in water. After being wetted with an aqueous phase, the electrospun mask has perfect conformability and biocompatibility, enabling the loaded lavender essential oil to come into more sufficient contact with the skin and penetrate into the skin.

[0025] 4. The preparation method of the present invention does not add additives, is gentle to the skin and has no irritation. The lavender essential oil, propylene glycol and polyvinyl alcohol of the present invention cooperate with each other, making the electrospun mask have the effects of moisturizing and nourishing the skin, repairing abrasions and sunburns, and antioxidant.

[0026] 5. The electrospinning setting of the present invention forms an ordered micro-nano structure, enhancing the mechanical properties of the electrospun mask and making the electrospun mask more durable.

[0027] 6. Electrospinning is a physical change, enabling the formed electrospun mask to maintain good stability.

[0028] 7. The preparation method of the present invention can flexibly adjust the electrospinning parameters according to actual needs to prepare personalized electrospun mask products. Description of the Drawings

[0029] Figure 1 is the pH value of the electrospun mask obtained in Example 1;

[0030] Figure 2 is the animal test result diagram of the electrospun mask obtained in Example 1;

[0031] Figure 3 is the SEM photograph of the electrospun mask obtained in Example 1;

[0032] Figure 4 is the SEM image of the electrospun mask obtained in Example 2;

[0033] Figure 5 is the nanofiber diameter distribution diagram of the electrospun mask obtained in Example 2;

[0034] Figure 6 is the SEM image of the electrospun mask obtained in Example 3;

[0035] Figure 7 is the nanofiber diameter distribution diagram of the electrospun mask obtained in Example 3;

[0036] Figure 8 is the SEM image of the electrospun mask obtained in Example 4;

[0037] Figure 9 is the nanofiber diameter distribution diagram of the electrospun mask obtained in Example 4. Detailed Embodiments

[0038] The present invention provides a preparation method of a lavender essential oil electrospun mask, comprising the following steps:

[0039] Mix lavender essential oil, propylene glycol, polyvinyl alcohol and water to form a spinning solution;

[0040] Perform electrospinning on the spinning solution to obtain the lavender essential oil electrospun mask;

[0041] In the spinning solution, based on the volume of water, the mass fraction of polyvinyl alcohol is 7-9%, the mass fraction of propylene glycol is 4-6%, and the lavender essential oil accounts for 0%-20% of the mass of propylene glycol, not 0%;

[0042] The parameters of the electrospinning include: voltage of 15-20 kV, receiving distance of 16 cm, injection speed of 0.04-0.07 mm / min, receiving speed of 140 r / min, and translation speed of 200 mm / min.

[0043] Unless otherwise specified, the raw materials used in the present invention are preferably commercially available products.

[0044] The present invention mixes lavender essential oil, propylene glycol, polyvinyl alcohol and water to form a spinning solution.

[0045] In the present invention, in the spinning solution, based on the volume of water, the mass fraction of polyvinyl alcohol is preferably 7-9%, specifically preferably 7%, 8% or 9%. In a specific embodiment of the present invention, the polyvinyl alcohol is specifically preferably of the 1799 type. In the present invention, polyvinyl alcohol (PVA) is a synthetic polymer formed by the polymerization of vinyl alcohol monomers. It is a solid from colorless to light yellow, usually in the form of powder, granules or flakes, and can also be used as a water-soluble polymer. In the present invention, the polyvinyl alcohol is the framework material of the electrospun mask and is used to carry the lavender essential oil.

[0046] In the present invention, in the spinning solution, based on the volume of water, the mass fraction of propylene glycol is 4-6%, specifically preferably 4%, 5% or 6%. In the present invention, propylene glycol is a small molecule organic compound, which is a colorless, odorless viscous liquid under normal conditions and has functions such as moisturizing, solubilizing, antioxidant, enhancing permeability, antibacterial, etc. Its functions are to relieve dryness, dissolve dirt, beautify the skin, promote absorption, inhibit bacteria, etc.

[0047] In the present invention, in the spinning solution, the lavender essential oil accounts for 0%-20% of the mass of the propylene glycol, not 0%, preferably accounts for 0.1%-20% of the mass of the propylene glycol, and further preferably accounts for 13%-17% of the mass of the propylene glycol, specifically preferably 0.1%, 1%, 5%, 10%, 13%, 15%, 17% or 20%. In the present invention, the lavender essential oil is extracted from lavender and has skin care effects such as cleaning the skin, controlling oil, removing spots and whitening, moisturizing and rejuvenating the skin, removing eye bags and dark circles, and promoting the regeneration and recovery of damaged tissues. At the same time, the lavender essential oil can quickly eliminate oil secretion, is suitable for treating acne caused by emotional stress, and can also fade acne marks and scars. It can promote cell regeneration, accelerate wound healing, and has a bactericidal and anti-inflammatory effect, and is suitable for treating burns, sunburns and fading scars. The lavender essential oil can relieve and treat insomnia symptoms caused by stress, emotional anxiety and hormonal imbalance, and has a miraculous calming and soothing effect. It can soothe tense emotions, calm the mind and calm the qi. For example, the volatile oil extracted from lavender is used to improve the sleep of the elderly; the whole herb preparation of lavender can also be used to treat neurasthenia and insomnia. The lavender essential oil is highly volatile and easily causes the loss of active ingredients. In the present invention, through electrospinning, the physical encapsulation of the essential oil is achieved by using the three-dimensional network structure formed by polyvinyl alcohol nanofibers.

[0048] In the present invention, the water is preferably deionized water.

[0049] In the present invention, the mixing of the lavender essential oil, propylene glycol, polyvinyl alcohol and water preferably comprises the following steps: firstly mixing the lavender essential oil and propylene glycol to obtain an oil phase; secondly mixing the polyvinyl alcohol and water to obtain an aqueous phase; and thirdly mixing the oil phase and the aqueous phase. In the present invention, the temperature of the first mixing is preferably 75 - 85°C, more preferably 80°C; the time is preferably 1 - 3 h, more preferably 2 h. In the present invention, the temperature of the second mixing is preferably 75 - 85°C, more preferably 80°C; the time is preferably 3 - 5 h, more preferably 4 h. In the present invention, the temperature of the third mixing is preferably 75 - 85°C, more preferably 80°C; the time is preferably 10 - 50 min, more preferably 30 min. In the present invention, the first mixing, the second mixing and the third mixing are all preferably carried out in a magnetic stirrer, and the model of the magnetic stirrer is preferably DF-101S.

[0050] After forming the spinning solution, the present invention electrospins the spinning solution to obtain the lavender essential oil electrospun mask.

[0051] In the present invention, the parameters of the electrospinning include: the voltage is 15 - 20 kV, specifically preferably 16 - 18 kV, specifically preferably 14 kV, 15 kV, 15.5 kV, 16 kV, 16.5 kV, 17 kV, 18 kV, 18.5 kV or 20 kV; the receiving distance is 16 cm; the pushing speed is 0.04 - 0.07 mm / min, specifically preferably 0.04 mm / min, 0.05 mm / min, 0.06 mm / min or 0.07 mm / min; the receiving speed is 140 r / min; the translation speed is 200 mm / min. In the present invention, the parameters of the electrospinning further include: the needle number is preferably 22-gauge; the receiver is preferably a roller, and the roller is preferably covered with tin foil.

[0052] In the present invention, the environmental parameters of the electrospinning include: the spinning temperature is preferably 30°C ± 3°C, and the spinning humidity is preferably 25% ± 5%.

[0053] After the electrospinning, the present invention preferably further comprises: collecting by a collecting device to obtain the lavender essential oil electrospun mask.

[0054] The preparation method provided by the present invention uses polyvinyl alcohol as a carrier and water as a solvent to encapsulate lavender essential oil to prepare an electrospun mask.

[0055] The present invention also provides a lavender essential oil electrospun mask prepared by the preparation method described in the above technical solution.

[0056] In the present invention, the lavender essential oil electrospun mask is preferably used in combination with an aqueous phase; the aqueous phase is preferably water; the water is preferably deionized water or distilled water.

[0057] In the present invention, the lavender essential oil electrospun mask is a dry film, which is used after being sprayed wet with an aqueous phase during use.

[0058] The present invention also provides a method for using the lavender essential oil electrospun mask according to the above technical solution, comprising the following steps:

[0059] Spray the lavender essential oil electrospun mask wet with an aqueous phase and use it.

[0060] In the present invention, the composition of the aqueous phase is preferably the same as that of the above technical solution, which will not be elaborated herein.

[0061] In a specific embodiment of the present invention, the specific method for using the lavender essential oil electrospun mask preferably comprises the following steps:

[0062] 1. Clean the facial skin

[0063] Before using the mask, please first clean the facial skin, remove dirt, oil and cosmetic residues, gently dry the skin, and keep the skin moist.

[0064] 2. Open the package of the lavender essential oil electrospun mask

[0065] Open the package, keep your hands clean, take out the lavender essential oil electrospun mask, carefully unfold it and apply it on the face. Since the lavender essential oil electrospun mask uses electrospinning technology and uses a water-soluble polymer as the matrix, it is dry during packaging and transportation and does not contain moisture. During use, it needs to be sprayed wet with an aqueous phase spray to make it adhere to the face.

[0066] 3. Apply the mask

[0067] Relax and enjoy 3 minutes of beauty time to allow the skin to fully absorb the essence.

[0068] 4. Remove the mask

[0069] Remove the mask and gently massage it along the skin texture until it is absorbed.

[0070] 5. Subsequent skin care

[0071] There is no need to clean the skin again after use, and subsequent daily skin care steps can be carried out according to needs, such as applying a moisturizing cream to lock in moisture and nutrients.

[0072] In the present invention, the preferred usage frequency of the lavender essential oil electrospun mask is: it is recommended to use it 2 - 3 times a week, and the frequency can be adjusted according to the skin condition. If the skin is dry or there are specific skin care needs, the usage frequency can be appropriately increased.

[0073] Precautions for using the lavender essential oil electrospun mask in the present invention:

[0074] 1. Allergy test

[0075] Since everyone's skin is different, the adaptability to different cosmetics is also different. Please conduct a local trial before use. If discomfort or allergic reactions occur, please stop using immediately or consult a doctor. Do not use when there are abnormal skin conditions.

[0076] 2. Storage conditions

[0077] Please store it in a cool place and avoid high temperature and direct sunlight. After opening, please use it up as soon as possible to avoid deterioration of the active ingredients.

[0078] The present invention also provides the application of the lavender essential oil electrospun mask described in the above technical solution in the field of skin care.

[0079] The present invention does not specifically limit the application method of the electrospun mask, and those skilled in the art can set it according to actual needs.

[0080] The following examples will be used to describe in detail the lavender essential oil electrospun mask provided by the present invention, its preparation method, usage method and application, but they should not be construed as limiting the protection scope of the present invention.

[0081] The sources of raw materials used in the following examples are:

[0082] Polyvinyl alcohol, the 1799 type polyvinyl alcohol purchased from Shanghai Macklin Biochemical Co., Ltd., with an alcoholysis degree of 98 - 99; propylene glycol, purchased from Shanghai Macklin Biochemical Co., Ltd., with a purity of 99.9%; lavender essential oil, purchased from Yiparhan Co., Ltd.; deionized water was prepared in the laboratory.

[0083] Example 1

[0084] A preparation method of an electrospun mask includes the following steps:

[0085] (1) Weigh 2 g of polyvinyl alcohol in a 50 mL beaker, add 25 mL of deionized water, place it in a magnetic stirrer (DF-101S), and stir at 80 °C for 4 h to form an aqueous phase; weigh 1.25 g of propylene glycol, with the mass ratio of lavender essential oil to propylene glycol being 0:1.25 (0%), 0.0625:1.25 (5%), 0.125:1.25 (10%), 0.1875:1.25 (15%), or 0.25:1.25 (20%). Weigh the lavender essential oil, mix the propylene glycol and lavender essential oil, place it in a magnetic stirrer (DF-101S), and stir at 80 °C for 2 h to form an oil phase; after mixing the aqueous phase and the oil phase, place it in a magnetic stirrer (DF-101S) and stir at 80 °C for 30 min. After cooling to room temperature, it is reserved as a spinning solution.

[0086] (2) Add the obtained spinning solution to four 5 mL syringes, install a 22-gauge needle, place it in an electrospinning device, and then control the propulsion module in the electrospinning device to push until the liquid just drips out to ensure that the four syringes operate effectively at the same time, so that the spinning starts simultaneously. Cut the tin foil paper suitable for the size of the receiving roller in the electrospinning device, cover it on the receiving roller to spin a layer of nanofiber layer; set the operating parameters and environmental parameters of the electrospinning device and start spinning; among them, the operating parameters of the electrospinning device include: the spinning distance is 16 cm, the spinning voltage is 17 kV, the injection speed is 0.06 mm / min, the translation speed is 200 mm / min, the roller rotation speed is 140 r / min, and the environmental parameters include: the spinning temperature is 30 °C ± 3 °C, the spinning humidity is 25% ± 5%. Finally, electrospun masks are obtained, named electrospun mask - 0%, electrospun mask - 5%, electrospun mask - 10%, electrospun mask - 15%, and electrospun mask - 20% respectively.

[0087] Performance test

[0088] (1) pH test

[0089] Use pH test paper to characterize the pH value of the obtained electrospun mask

[0090] Cut electrospun mask - 0%, electrospun mask - 5%, electrospun mask - 10%, electrospun mask - 15%, and electrospun mask - 20% into the same size (1×1 cm 2 ), completely dissolve them in 4 mL of deionized water, and at the same time set up a control group (deionized water group). Use pH test paper to measure the pH value of each group of solutions after 10 min respectively.

[0091] The test results are as Figure 1 shown. Figure 1 is the pH value of the obtained electrospun mask, Figure 1Among them, from left to right are the pH test results of the control group, electrospun mask - 0%, electrospun mask - 5%, electrospun mask - 10%, electrospun mask - 15%, and electrospun mask - 20%. From Figure 1 It can be seen that: by comparing with the colorimetric card, the pH values of each group are 7, 7, 7, 7, 7, 7 from left to right, meeting the standard of the pH value of human skin.

[0092] (2) Animal experiment

[0093] A mouse skin sunburn model was made by irradiating with an ultraviolet lamp, and electrospun mask - 0%, electrospun mask - 5%, electrospun mask - 10%, electrospun mask - 15%, and electrospun mask - 20% were applied to its wound every day. At the same time, a control group was set up, that is, no treatment after sunburn. After two weeks, the recovery effects of different groups were observed, and the test results are as Figure 2 shown.

[0094] Figure 2 It is the animal experiment result diagram of the obtained electrospun mask. Figure 2 Among them, 0D represents the sunburned mouse model without applying the mask, 2D represents applying the mask for 2 days, 4D represents applying the mask for 4 days, 9D represents applying the mask for 9 days, and 14D represents applying the mask for 14 days; from Figure 2 It can be seen that: in the range of 0% - 15% of the mass of lavender essential oil in propylene glycol, with the increase of the content of lavender essential oil, the efficacy of the prepared electrospun mask also increases. When the lavender essential oil accounts for 15% of the mass of propylene glycol, the obtained electrospun mask has the best effect.

[0095] (3) Moisture retention performance test

[0096] The skin moisture of 8 randomly selected participants was tested using a skin detector, ensuring that they did not use other skin care products in the week before the test and within two weeks of the experiment. The average skin moisture content after daily use was measured respectively. The test results are shown in Table 1.

[0097] Table 1 Moisture retention test results

[0098]

[0099] It can be seen from Table 1 that: during the use of the electrospun mask, the skin moisture contents of the three groups with 5%, 15%, and 20% of the mass of lavender essential oil in propylene glycol are significantly increased and relatively stable compared with the blank group (0%). The skin moisture content measured every day exceeds 45%, showing a good skin moisture retention effect.

[0100] (4) Hydrophilicity

[0101] Cut samples of electrospun masks - 0%, electrospun masks - 5%, electrospun masks - 10%, electrospun masks - 15%, and electrospun masks - 20% into appropriate sizes. Using a micro syringe or a dropping system, gently drop a certain volume (such as 3 μL or 50 μL) of water droplets onto the surface of the electrospun masks. Capture the images of the droplets in contact with the electrospun masks at the moment of contact using a high - resolution camera. Through image - processing technology, automatically measure the angle between the droplets and the surface of the electrospun masks. The results are as follows: the water contact angles of the obtained electrospun masks - 0%, electrospun masks - 5%, electrospun masks - 10%, electrospun masks - 15%, and electrospun masks - 20% are 66.175°, 59.031°, 47.799°, 29.445°, and 26.792° in sequence. It can be seen that as the mass fraction of lavender essential oil in propylene glycol increases, the water contact angle becomes smaller and the electrospun masks have better hydrophilicity. Polyvinyl alcohol and lavender essential oil have hydrophilicity, making the electrospun masks easily soluble in water. Secondly, the electrospun fibers have the advantages of a large specific surface area and a high porosity, making the contact surface between the fibers and water larger and more easily soluble in water.

[0102] (5) Rapid solubility

[0103] Immerse the electrospun masks in water. At the beginning stage, they show excellent hydrophilicity, and the electrospun masks are quickly wetted by water. For electrospun masks - 0% and electrospun masks - 5%, nearly half of them have dissolved within 1 s and are completely dissolved at 3 s; for electrospun masks - 10%, nearly half of them have dissolved within 5 s and are completely dissolved at 10 s; for electrospun masks - 15%, nearly half of them have dissolved within 8 s and are completely dissolved at 24 s; for electrospun masks - 20%, nearly half of them have dissolved within 40 s, but then the mask dissolves slowly and is not completely dissolved at 360 s. The excellent hydrophilicity of the electrospun masks allows them to dissolve quickly in water, which is beneficial for the effective release of the active substances inside the nanofibers in water.

[0104] (6) Bacterial content test

[0105] First, disinfect the sampling bottles with 75% alcohol. After allowing them to dry naturally, cut five groups of electrospun masks into the same size (1×1 cm 2 ) and place them in the sampling bottles. Then add 100 mL of deionized water. Each sample is measured in triplicate to detect the total number of colonies. The test results are shown in Table 2.

[0106] Table 2 Test results of the bacterial content of the obtained electrospun masks

[0107]

[0108]

[0109] As can be seen from Table 2, in the obtained electrospun masks, the total number of bacterial and mold colonies formed in the groups with 0% and 5% lavender essential oil in propylene glycol was relatively high, while the total number of colonies in the remaining groups was 0.

[0110] (7) SEM / TEM detection

[0111] Figure 3 is the SEM photo of the obtained electrospun mask. Figure 3 Among them, from left to right and top to bottom are the SEM photos of electrospun mask - 0%, electrospun mask - 5%, electrospun mask - 10%, electrospun mask - 15% and electrospun mask - 20%, and the scale bars are all 10 μm. From Figure 3 it can be seen that the addition of lavender essential oil does not have a great impact on the morphology of the fibers. The fiber distribution is relatively uniform, and there are no beading and entanglement phenomena. The average diameters of the nanofibers corresponding to electrospun mask - 0%, electrospun mask - 5%, electrospun mask - 10%, electrospun mask - 15% and electrospun mask - 20% are 317.68 nm, 323.33 nm, 290.00 nm, 317.17 nm, 307.67 nm respectively; it can be seen that the fiber diameter does not increase or decrease with the content of lavender essential oil, and the average diameter of the nanofibers is stable at 311.17 ± 13.10 nm.

[0112] Example 2

[0113] (1) Weigh 1.75 g, 2 g or 2.25 g of polyvinyl alcohol in a 50 mL beaker respectively, add 25 mL of deionized water, place it in a magnetic stirrer (DF - 101S) and stir at 80 °C for 4 h to form an aqueous phase. The mass concentrations of polyvinyl alcohol in the aqueous phase are 7%, 8% or 9% in turn; weigh 1.25 g of propylene glycol and mix it with 0.1875 g of lavender essential oil (the mass of lavender essential oil is 15% of the mass of propylene glycol), place it in a magnetic stirrer (DF - 101S) and stir at 80 °C for 2 h to form an oil phase; after mixing the aqueous phase and the oil phase, place it in a magnetic stirrer (DF - 101S) and stir at 80 °C for 30 min, and after cooling to room temperature, use it as a spinning solution for standby.

[0114] The others are the same as in Example 1, and the obtained electrospun masks are named electrospun mask - PVA7, electrospun mask - PVA8 and electrospun mask - PVA9 respectively.

[0115] The water contact angles of the obtained electrospun mask - PVA7, electrospun mask - PVA8 and electrospun mask - PVA9 are 42.159°, 29.445° and 30.432° in turn.

[0116] Figure 4 is the SEM image of the obtained electrospun mask.Figure 4 In the middle, from left to right and from top to bottom are the SEM images of electrospun mask-PVA7, electrospun mask-PVA8, and electrospun mask-PVA9;

[0117] Figure 5 is the nanofiber diameter distribution diagram of the obtained electrospun mask, Figure 5 In the figure, from left to right and from top to bottom are the nanofiber diameter distribution diagrams of electrospinning mask-PVA7, electrospinning mask-PVA8, and electrospinning mask-PVA9. Figure 4 and Figure 5 It can be seen that: when the mass fraction of PVA is 7%, the average fiber diameter is 237.05nm, and the fibers are distributed in the range of 60nm to 430nm, among which most of the fiber diameters are between 200 and 300nm, accounting for 46.51% of the total; the statistical mean fiber diameter is 0.23705μm, and the standard deviation is 0.07575; some fibers are entangled and have a beaded structure, and the fiber thickness distribution is very uneven. This is because the polymer concentration in the spinning solution is too low, the polymer content is too little, and the polymer chain will break before reaching the collector; in addition, the polymer concentration in the spinning solution is too low and the viscosity is too small, resulting in thin fibers that are prone to entanglement. The nanofibers formed under the influence of these two factors will have fiber entanglement and a beaded structure. When the mass fraction of PVA is 8%, the average fiber diameter is 224.13nm, and the fiber distribution is in the range of 120nm to 420nm, among which most of the fiber diameters are between 225 and 275nm, accounting for 58.14% of the total proportion; the statistical mean fiber diameter is 0.25823μm, and the standard deviation is 0.06218; the fiber diameter is evenly distributed and straight cylindrical, and there is no beaded structure. When the mass fraction of PVA is 9%, the average fiber diameter is 442.70nm, and the fiber distribution is in the range of 15nm to 1200nm, among which most of the fiber diameters are between 300 and 400nm, accounting for 23.26% of the total proportion; the statistical mean fiber diameter is 0.44270μm, and the standard deviation is 0.20598; the fiber distribution is uneven and the fiber has entanglement, which is due to the increase in fiber diameter, which leads to incomplete drying when the fiber reaches the collection plate, resulting in entanglement. As the concentration of PVA increases, the viscosity increases, the fluidity of the spinning solution deteriorates, it becomes more difficult to stretch when the electric field strength remains unchanged, and the average diameter of the fiber continues to increase.

[0118] Example 3

[0119] (1) Weigh 2 g of polyvinyl alcohol in a 50 mL beaker, add 25 mL of deionized water, place it in a magnetic stirrer (DF-101S), and stir at 80 °C for 4 h to form an aqueous phase; weigh 1.25 g of propylene glycol, with the mass ratio of lavender essential oil to propylene glycol being 0.1875:1.25 (15%), weigh lavender essential oil, mix propylene glycol and lavender essential oil, place it in a magnetic stirrer (DF-101S), and stir at 80 °C for 2 h to form an oil phase; after mixing the aqueous phase and the oil phase, place it in a magnetic stirrer (DF-101S), stir at 80 °C for 30 min, and after cooling to room temperature, use it as a spinning solution for standby.

[0120] (2) Add the obtained spinning solution to four 5 mL syringes, install a 22-gauge needle, place it in an electrospinning device, and then control the propulsion module in the electrospinning device to push until the liquid just drips out to ensure the simultaneous and effective operation of the four syringes and start spinning simultaneously. Cut tinfoil paper suitable for the size of the receiving roller in the electrospinning device and cover it on the receiving roller to spin a layer of nanofiber layer; set the operating parameters and environmental parameters of the electrospinning device and start spinning; among them, the operating parameters of the electrospinning device include: the spinning distance is 16 cm, the spinning voltages are set to 15.5 kV, 17 kV, 18.5 kV, or 20 kV respectively; the injection speed is 0.06 mm / min, the translation speed is 200 mm / min, the roller rotation speed is 140 r / min, and the environmental parameters include: the spinning temperature is 30 °C ± 3 °C, the spinning humidity is 25% ± 5%, and finally, electrospun masks are obtained, named electrospun mask - 15.5 kV, electrospun mask - 17 kV, electrospun mask - 18.5 kV, and electrospun mask - 20 kV respectively.

[0121] The water contact angles of the obtained electrospun mask - 15.5 kV, electrospun mask - 17 kV, electrospun mask - 18.5 kV, and electrospun mask - 20 kV are 27.987°, 29.445°, 34.915°, and 56.339° in sequence.

[0122] Figure 6 is the SEM image of the obtained electrospun mask, Figure 6 in which, from left to right and from top to bottom are the SEM images of electrospun mask - 15.5 kV, electrospun mask - 17 kV, electrospun mask - 18.5 kV, and electrospun mask - 20 kV respectively; Figure 7 is the nanofiber diameter distribution diagram of the obtained electrospun mask, Figure 7 in which, from left to right and from top to bottom are the nanofiber diameter distribution diagrams of electrospun mask - 15.5 kV, electrospun mask - 17 kV, electrospun mask - 18.5 kV, and electrospun mask - 20 kV respectively; from Figure 6 andFigure 7 It can be seen that: when the spinning voltage is 15.5kV, the average fiber diameter of the obtained electrospinning mask is 266.19nm, the fiber diameter is evenly distributed and is in a straight cylindrical shape, and there is no beaded structure; the fibers are distributed in the range of 150-450nm, among which most of the fiber diameters are between 230 and 290nm, accounting for 55.81% of the total; the statistical mean fiber diameter is 0.26619μm, and the standard deviation is 0.05886. When the spinning voltage is 17kV, the average fiber diameter is 258.23nm, and the fibers are distributed in the range of 120nm to 420nm, among which most of the fiber diameters are between 210 and 290nm, accounting for 58.14% of the total; the statistical mean fiber diameter is 0.25823μm, and the standard deviation is 0.06218; the fiber diameter is evenly distributed and is in the shape of a straight cylinder, and no beaded structure appears; it is not much different from the electrospinning voltage of 15.5kV. When the spinning voltage is 18.5kV, the average fiber diameter is 223.70nm, and the fiber distribution is in the range of 100nm to 330nm. Among them, most of the fiber diameters are between 180 and 240nm, accounting for 48.84% of the total proportion; the statistical mean fiber diameter is 0.22370μm, and the standard deviation is 0.04772; compared with the spinning voltage of 17kV, the mask fibers are denser, but there are a small number of fiber entanglements and beads. When the spinning voltage is 20kV, the average fiber diameter is 193.16nm, and the fiber distribution is in the range of 80nm to 410nm. Among them, most of the fiber diameters are between 180 and 240nm, accounting for 44.19% of the total proportion; the statistical mean fiber diameter is 0.19316μm, and the standard deviation is 0.05679; the mean fiber diameter has decreased, the mask fibers are denser, but more fibers are entangled.

[0123] In summary, in the range of 17kV to 20kV, the water contact angle gradually increases, indicating that the hydrophilicity decreases. This may be because when the spinning voltage increases, the electric field force increases, the jet stretching is more intense, and finer fibers are generated. Fine fibers may form a denser microstructure when deposited, increasing the surface roughness, and the surface roughness will amplify the intrinsic contact angle. Therefore, in the range of 15.5kV to 20kV, the voltage should not be too large or too small, otherwise the fiber distribution of the mask will be uneven and the water contact angle will increase. Therefore, 17kV was selected as the optimal spinning voltage.

[0124] Example 4

[0125] (1) Weigh 2 g of polyvinyl alcohol in a 50 mL beaker, add 25 mL of deionized water, place it in a magnetic stirrer (DF-101S), and stir at 80 °C for 4 h to form an aqueous phase; weigh 1.25 g of propylene glycol, with the mass ratio of lavender essential oil to propylene glycol being 0.1875:1.25 (15%), weigh lavender essential oil, mix propylene glycol and lavender essential oil, place it in a magnetic stirrer (DF-101S), and stir at 80 °C for 2 h to form an oil phase; after mixing the aqueous phase and the oil phase, place it in a magnetic stirrer (DF-101S) and stir at 80 °C for 30 min. After cooling to room temperature, it is reserved as a spinning solution.

[0126] (2) Add the obtained spinning solution into four 5 mL syringes, install 22-gauge needles, place them in an electrospinning device, and then control the propulsion module in the electrospinning device to push until the liquid just drips out to ensure the simultaneous and effective operation of the four syringes, so that the spinning starts simultaneously. Cut tinfoil suitable for the size of the receiving roller in the electrospinning device and cover it on the receiving roller to spin a layer of nanofiber layer; set the operating parameters and environmental parameters of the electrospinning device and start spinning; among them, the operating parameters of the electrospinning device include: the spinning distance is 16 cm, the spinning voltage is set at 17 kV; the injection speeds are 0.04 mm / min, 0.05 mm / min, 0.06 mm / min, or 0.07 mm / min respectively, the translation speed is 200 mm / min, and the roller rotation speed is 140 r / min. The environmental parameters include: the spinning temperature is 30 °C ± 3 °C, and the spinning humidity is 25% ± 5%. Finally, electrospun masks are obtained, namely electrospun mask - 0.04 mm / min, electrospun mask - 0.05 mm / min, electrospun mask - 0.06 mm / min, and electrospun mask - 0.07 mm / min.

[0127] The water contact angles of the obtained electrospun mask - 0.04 mm / min, electrospun mask - 0.05 mm / min, electrospun mask - 0.06 mm / min, and electrospun mask - 0.07 mm / min are 35.038°, 32.726°, 29.445°, and 38.367° in sequence.

[0128] Figure 8 is the SEM image of the obtained electrospun mask, Figure 8 Among them, from left to right and from top to bottom are the SEM images of electrospun mask - 0.04 mm / min, electrospun mask - 0.05 mm / min, electrospun mask - 0.06 mm / min, and electrospun mask - 0.07 mm / min in sequence; Figure 9 is the nanofiber diameter distribution diagram of the obtained electrospun mask, Figure 9In the figure, from left to right and from top to bottom are the nanofiber diameter distribution diagrams of electrospinning mask - 0.04mm / min, electrospinning mask - 0.05mm / min, electrospinning mask - 0.06mm / min, and electrospinning mask - 0.07mm / min. Figure 8 and Figure 9 It can be seen that when the push speed is 0.04mm / min, the average fiber diameter of the electrospun mask is 232.023nm, and the fiber distribution is in the range of 60nm to 1200nm, among which most of the fiber diameters are between 100nm and 200nm, accounting for 32.56% of the total proportion; the statistical mean fiber diameter is 0.23202μm, and the standard deviation is 0.19306. When the push speed is 0.05mm / min, the average fiber diameter of the electrospun mask is 263.93nm, and the fiber distribution is in the range of 130nm to 640nm, among which most of the fiber diameters are between 200nm and 300nm, accounting for 55.81% of the total proportion; the statistical mean fiber diameter is 0.26393μm, and the standard deviation is 0.09710. When the push speed is 0.06mm / min, the average fiber diameter of the electrospun mask is 258.233nm, and the fiber distribution is in the range of 150nm to 450nm, among which most of the fiber diameters are between 200nm and 300nm, accounting for 58.14% of the total proportion; the statistical mean fiber diameter is 0.25823μm, and the standard deviation is 0.06218; the fiber diameter is evenly distributed and straight cylindrical, and there is no beaded structure. When the push speed is 0.07mm / min, the average fiber diameter of the electrospun mask is 262.12nm, and the fiber distribution is in the range of 130nm to 720nm, among which most of the fiber diameters are between 200nm and 300nm, accounting for 48.84% of the total proportion; the statistical mean fiber diameter is 0.26212μm, and the standard deviation is 0.10067. Therefore, considering the hydrophilicity and fiber morphology, the injection speed of 0.06 mm / min is preferred.

[0129] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A method for preparing a lavender essential oil electrospinning facial mask, characterized in that: The following steps are involved: Mixing lavender essential oil, propylene glycol, polyvinyl alcohol and water to form a spinning solution; The spinning solution is subjected to electrostatic spinning to obtain the lavender essential oil electrostatic spinning mask; In the spinning solution, based on the volume of water, the mass fraction of polyvinyl alcohol is 7-9%, the mass fraction of propylene glycol is 4-6%, and the lavender essential oil accounts for 0% to 20% of the mass of the propylene glycol, not 0%; The parameters of the electrospinning include: voltage of 15-20 kV, receiving distance of 16 cm, injection speed of 0.04-0.07 mm / min, receiving speed of 140 r / min, and translation speed of 200 mm / min.

2. The preparation method according to claim 1, characterized in that: The mixing of lavender essential oil, propylene glycol, polyvinyl alcohol and water comprises the following steps: first mixing lavender essential oil and propylene glycol to obtain an oil phase; second mixing polyvinyl alcohol and water to obtain an aqueous phase; and third mixing the oil phase and the aqueous phase.

3. The preparation method according to claim 2, characterized in that: The temperature of the first mixing is 75-85°C, and the time is 1-3 hours; the temperature of the second mixing is 75-85°C, and the time is 3-5 hours; the temperature of the third mixing is 75-85°C, and the time is 10-50 minutes.

4. The preparation method according to claim 1, characterized in that: The electrospinning parameters also include: the needle number is 22.

5. The preparation method according to claim 1, characterized in that: The environmental parameters of the electrostatic spinning include: a spinning temperature of 30±3° C. and a spinning humidity of 25±5%.

6. Lavender essential oil electrospinning mask prepared by the preparation method according to any one of claims 1 to 5.

7. The lavender essential oil electrospinning mask according to claim 6, characterized in that: The electrospinning facial mask is used in conjunction with an aqueous phase; the aqueous phase is water.

8. The method for using the lavender essential oil electrospinning facial mask according to claim 6 or 7, characterized in that: The following steps are involved: The lavender essential oil electrospinning facial mask is sprayed with a water phase for use.

9. The method of use according to claim 8, characterized in that: The aqueous phase is water.

10. Use of the lavender essential oil electrospinning mask according to any one of claims 6 to 7 in the field of skin care.

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