Whole-brain sleep regulation and control method and device based on ultrasonic-infrasound coupled sound waves

Abstract

The invention relates to the field of ultrasonic sleep aiding, and provides an ultrasonic-infrasound coupled sound wave whole-brain sleep regulation and control method and device. The whole-brain sleep regulation and control method based on the ultrasound-infrasound coupling sound waves comprises the steps that electroencephalogram signals of a user are collected through electroencephalogram collection equipment; physiological parameters of the user are obtained through physiological state monitoring equipment; a control device is adopted to control and adjust the fundamental frequency, pulse width, pulse repetition frequency, difference frequency, intensity and other parameters of two columns of ultrasonic waves generated by a sound wave emission device according to the electroencephalogram signals and the physiological parameters; a sound wave emitting device is adopted to generate and emit two columns of ultrasonic waves which are close in frequency and face to face, the two columns of ultrasonic waves are fed into the brain face to face, and the two columns of ultrasonic signals inhibit the cerebral cortex activity when passing through the cerebral cortex; meanwhile, interference occurs in the deep brain target nuclear region, low-frequency infrasound beat frequency waves are formed, electroencephalogram slow wave rhythm resonance is induced, sleep-related neural activities of the deep brain target nuclear region are synchronized, and coordinated regulation and control of the whole brain region are achieved.

Description

Technical Field

[0001] The present invention relates to the technical field of ultrasonic sleep assistance, and particularly to a method and device for regulating whole-brain sleep by coupling ultrasonic and infrasonic waves. Background Technique

[0002] The statements in this part merely provide background technical information related to the present invention and do not necessarily constitute prior art.

[0003] To solve the problems of difficulty in falling asleep and poor sleep quality, currently there are mainly four existing brain function regulation means that can achieve non-invasive physical stimulation to relieve sleep disorders: transcranial magnetic stimulation, transcranial electrical stimulation, light stimulation, and acoustic wave stimulation. Among them: Transcranial magnetic stimulation (TMS) penetrates the skull through a high-intensity pulsed magnetic field to generate an induced current in the cerebral cortex to regulate nerve activity. However, due to relying on a large-capacity energy storage capacitor to generate a high-intensity magnetic field, the device is large in size and difficult to miniaturize; Transcranial electrical stimulation (TES) directly acts on the brain region with a low-intensity current, having the advantages of small size, low cost, and flexible parameter adjustment. However, the stimulation range is limited to the cerebral cortex, difficult to penetrate deep into the brain nuclei, and there are significant individual response differences; Light stimulation indirectly regulates the suprachiasmatic nucleus circadian rhythm center and inhibits pineal gland melatonin secretion by activating retinal ganglion cells. Although the regulation method is gentle and natural, it has a slow onset and is not suitable for scenarios that require rapid adjustment of the sleep or wake state; Acoustic wave stimulation is divided into ultrasonic waves and infrasonic waves. Among them, ultrasonic waves regulate the brain function state by activating or inhibiting the cerebral cortex, and infrasonic waves promote sleep by inducing slow brain waves through rhythmic resonance. This technology has high safety, no obvious side effects, and can be modulated bidirectionally and targetedly. However, the focusing range of low-intensity ultrasonic waves is small and mostly acts on the cerebral cortex; while the infrasonic wave generating device is large and difficult to miniaturize.

[0004] Existing technologies use devices for single ultrasonic wave sleep assistance or single infrasonic wave sleep assistance. Among them, single ultrasonic wave sleep assistance can achieve precise spatial positioning by virtue of the millimeter-level short wavelength characteristics, but its sound field attenuation gradient increases exponentially with depth (the skull absorption coefficient reaches 20 dB / cm at a frequency of 1 MHz), resulting in the effective stimulation range being limited to the surface 3-5 mm cortical area and difficult to penetrate deep into the brain regions; while single infrasonic wave sleep assistance has the advantage of centimeter-level penetration depth (the attenuation coefficient of 0.1 Hz infrasonic waves in brain tissue is only 0.01 dB / m). However, to maintain a sound pressure level below 80 dB below the auditory threshold while ensuring effective energy deposition, a high-power transducer array and a complex impedance matching system need to be configured, which makes the volume of the infrasound generating device usually exceed 30×30×50 cm³, difficult to miniaturize, unable to meet the demand for portable use, and there is a core contradiction that it is difficult to balance the penetration depth and the device volume.

[0005] In addition, the acoustic wave sleep aid devices in the prior art rely on the cochlear auditory conduction pathway to achieve signal transmission. They trigger continuous electrical activity in the auditory nerve through exogenous acoustic wave stimulation. Long-term exposure not only causes progressive auditory damage but also can induce three levels of pathological effects: disturbing the circadian rhythm stability of the sleep-wake cycle and leading to a decline in cognitive processing efficiency in the short term, and the long-term cumulative effect is more likely to extend to metabolic imbalance in the cardiovascular system. More notably, such a peripheral conduction mode has a fundamental technical limitation - the lack of the ability to target and regulate the central nervous system and the inability to directly regulate the neural activities of brain tissues. Summary of the Invention

[0006] Aiming at the contradiction between the penetration depth and the device portability existing in the existing acoustic wave nerve regulation technology (ultrasonic focusing is shallow, and infrasonic devices are large-sized), the present invention proposes a whole-brain sleep regulation method and device using ultrasonic-infrasonic coupled acoustic waves, supplemented by sleep state monitoring and feedback, which can achieve real-time personalized electroencephalogram regulation, relieve sleep disorders, and improve sleep quality.

[0007] To achieve the above object, the present invention adopts the following technical solutions.

[0008] The first aspect of the present invention provides a whole-brain sleep regulation device using ultrasonic-infrasonic coupled acoustic waves.

[0009] A whole-brain sleep regulation device using ultrasonic-infrasonic coupled acoustic waves includes: a pillow body, and an acoustic wave emitting device, an electroencephalogram acquisition device, a physiological state monitoring device, and a control device arranged in the pillow body. The control device is connected to the acoustic wave emitting device, the electroencephalogram acquisition device, and the physiological state monitoring device; The acoustic wave emitting device is used to generate and emit two columns of ultrasonic waves with similar frequencies and traveling towards each other, feed the two columns of ultrasonic waves towards the brain, and the two columns of ultrasonic wave signals inhibit the activities of the cerebral cortex when passing through the cerebral cortex; at the same time, they meet in the target nuclear area deep in the brain and interfere with each other to form a low-frequency infrasonic beat frequency wave to induce the resonance of electroencephalogram slow wave rhythm and synchronize the sleep-related neural activities in the target nuclear area deep in the brain; The electroencephalogram acquisition device is used to acquire the electroencephalogram signals of the user; The physiological state monitoring device is used to obtain the physiological parameters of the user; The control device is used to control and adjust the fundamental frequency, pulse width, pulse repetition frequency, difference frequency (the difference between the fundamental frequencies of the two columns of ultrasonic waves, hereinafter referred to as "difference frequency" for short), and intensity of the two columns of ultrasonic waves generated by the acoustic wave emitting device according to the electroencephalogram signals and physiological parameters.

[0010] Further, the acoustic wave emitting device includes: a signal generator, a power amplifier, and two ultrasonic generating devices, The signal generator is used to generate an electrical excitation signal to control two ultrasonic generating devices to generate ultrasonic waves that meet the requirements. The power amplifier is connected to the signal generator and is used to amplify the electrical excitation signal. The two ultrasonic generating devices are connected to the power amplifier and are used to generate two ultrasonic waves with similar frequencies and traveling in opposite directions.

[0011] Further, the low-frequency infrasonic beat wave is obtained by superimposing and interfering the ultrasonic waves generated by the two ultrasonic generating devices.

[0012] Further, the fundamental frequency range of the ultrasonic waves generated by the two ultrasonic generating devices is 20 kHz - 10 MHz.

[0013] Further, the low-frequency infrasonic beat wave is formed by superimposing and interfering two ultrasonic waves with similar frequencies and traveling in opposite directions, and the difference frequency range is 0.01 Hz - 100 Hz.

[0014] Further, the ultrasonic waves generated by the two ultrasonic generating devices propagate in opposite directions on the same straight line.

[0015] Further, the two ultrasonic generating devices are symmetrically arranged at both ends of the pillow body, so that the ultrasonic waves generated by them propagate on the same straight line and form a low-frequency infrasonic beat wave in the target deep brain area.

[0016] Further, the ultrasonic waves generated by the two ultrasonic generating devices include plane ultrasonic waves, line-focused ultrasonic waves or point-focused ultrasonic waves.

[0017] Further, the two ultrasonic generating devices include ultrasonic transducers.

[0018] The second aspect of the present invention provides a method for regulating whole-brain sleep with ultrasonic-infrasonic coupled sound waves.

[0019] A method for regulating whole-brain sleep with ultrasonic-infrasonic coupled sound waves, which is applied to the whole-brain sleep regulation device described in the first aspect, includes: Collecting the electroencephalogram signal of the user by using an electroencephalogram acquisition device; Obtaining the physiological parameters of the user by using a physiological state monitoring device; Using a control device to control and adjust parameters such as the fundamental frequency, pulse width, pulse repetition frequency, difference frequency and intensity of the two ultrasonic waves generated by the acoustic wave emitting device according to the electroencephalogram signal and physiological parameters; An acoustic wave emission device is used to generate and emit two ultrasonic waves with similar frequencies and moving towards each other. The two ultrasonic waves are fed into the brain in opposite directions. When the two ultrasonic wave signals pass through the cerebral cortex, they inhibit the activity of the cerebral cortex. At the same time, they meet in the target nucleus area deep in the brain and interfere with each other to form a low-frequency acoustic beat frequency wave, so as to induce the resonance of slow brain wave rhythm and synchronize the sleep-related nerve activities in the target nucleus area deep in the brain.

[0020] Compared with the prior art, the beneficial effects of the present invention are as follows: The present invention provides a whole-brain sleep regulation method and device based on ultrasonic-infrasonic coupled sound waves. Aiming at the contradiction between the penetration depth and the device portability existing in the existing acoustic wave nerve regulation technology (ultrasonic focusing is shallow, and infrasonic devices are large-sized), firstly, the double-source opposite ultrasonic beam difference frequency interference technology is adopted. In the cortical area, high-frequency ultrasonic waves of 20 kHz - 10 MHz are used for large-range rhythm modulation (covering nerve clusters with a diameter > 5 cm). At the same time, through the interference difference frequency phenomenon of the two ultrasonic beams (the difference frequency range is 0.01 Hz - 100 Hz), infrasonic oscillations with controllable energy density are generated at the beam intersection point, that is, the deep nucleus (such as the thalamus and hypothalamus), realizing the dual-modal coordination of "wide-area cortical regulation + precise resonance in the deep brain". Secondly, all acoustic wave parameters are strictly controlled within the non-auditory frequency band (ultrasonic > 20 kHz, infrasonic < 20 Hz) to ensure that the sound pressure level is always below the biological safety boundary of 80 dB. Finally, through modular design, the transducer array is integrated inside the pillow, which not only meets the portability requirements but also has the composite functions of whole-brain nerve rhythm synchronization and specific nucleus targeting regulation, not only meeting the convenient use requirements for the personalized needs of insomnia treatment but also taking into account the whole-brain rhythm regulation (universality) and specific brain area focusing regulation (personalization). Description of the Drawings

[0021] The specification drawings forming a part of the present invention are used to provide a further understanding of the present invention. The schematic embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an improper limitation of the present invention.

[0022] Figure 1 It is a structural diagram of the whole-brain sleep regulation device based on ultrasonic-infrasonic coupled sound waves shown in the embodiments of the present invention; Figure 2 It is a schematic diagram of generating an infrasonic frequency band using two ultrasonic waves in the beat frequency sound output scheme shown in the embodiments of the present invention; Figure 3 It is a schematic diagram of generating infrasonic oscillations at the focus using two focused ultrasonic waves with similar frequencies shown in the embodiments of the present invention; Figure 4 It is a flowchart of the whole-brain sleep regulation method based on ultrasonic-infrasonic coupled sound waves shown in the embodiments of the present invention; Among them, 1. Pillow body, 2. Ultrasonic generating device, 3. Power amplifier, 4. Signal generator, 5. Pillow side wall, 6. Groove, 7. A column of ultrasonic waves generating beat frequency phenomenon, 8. Another column of ultrasonic waves generating beat frequency phenomenon, 9. Low-frequency infrasonic beat frequency wave, 10. Control device, 11. Electroencephalogram acquisition device, 12. Physiological state monitoring device. Detailed implementation manners

[0023] The present invention will be further described below in conjunction with the accompanying drawings and embodiments.

[0024] It should be noted that the following detailed descriptions are all illustrative and are intended to provide further descriptions of the present invention. Unless otherwise specified, all technical and scientific terms used herein have the same meaning as commonly understood by those of ordinary skill in the technical field to which the present invention belongs.

[0025] It should be noted that the terms used herein are only for describing specific implementation manners and are not intended to limit the exemplary embodiments according to the present invention. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprising" and / or "including" are used in this specification, they indicate the presence of features, steps, operations, devices, components, and / or combinations thereof.

[0026] As introduced in the background technology, in the prior art, it is difficult for single ultrasonic wave to assist sleep to penetrate deep into the deep brain area; although single infrasonic wave can penetrate deep into the deep brain area, it is large in size and difficult to miniaturize, and there is a core contradiction that it is difficult to balance the penetration depth and the device size. Moreover, most of the sleep-assisting sound waves are audible sounds or single ultrasonic waves and infrasonic waves, and the acting modes mostly directly act on the auditory organs through headphones or other means, causing the inner ear to continuously convert sound signals into nerve signals and transmit them into the brain. This process will not only cause progressive damage to the auditory system, but also trigger a chain of physiological reactions: it can disrupt the sleep cycle rhythm and reduce the cognitive processing efficiency in the short term, and long-term exposure may even induce cardiovascular function damage.

[0027] Therefore, the present invention provides a neural regulation idea mainly based on whole-brain rhythm regulation and supplemented by focused regulation of sleep-related brain areas. Based on the different sleep regulation mechanisms and complementary action ranges of ultrasonic waves and infrasonic waves, a whole-brain sleep regulation technology, device and method of ultrasonic-infrasonic coupled sound waves are developed, supplemented by sleep state monitoring and feedback, which can realize real-time personalized electroencephalogram regulation, relieve sleep disorders and improve sleep quality.

[0028] The technical solutions of the present invention will be described in detail below through several embodiments.

[0029] Figure 1It is a structural diagram of an ultrasonic-infrasonic coupled acoustic wave whole-brain sleep regulation device shown in an embodiment of the present invention; as Figure 1 shown, the whole-brain sleep regulation device includes: a pillow body 1, and an acoustic wave emitting device, an electroencephalogram acquisition device 11, a physiological state monitoring device 12, and a control device 10 arranged in the pillow body 1. The control device 10 is connected to the acoustic wave emitting device, the electroencephalogram acquisition device 11, and the physiological state monitoring device 12; The acoustic wave emitting device is used to generate and emit two columns of ultrasonic waves with similar frequencies and traveling in opposite directions, feed the two columns of ultrasonic waves into the brain in opposite directions, and inhibit the activity of the cerebral cortex when the two columns of ultrasonic wave signals pass through the cerebral cortex; at the same time, they meet in the target nuclear area deep in the brain and interfere to form a low-frequency infrasonic beat frequency wave to induce electroencephalogram slow wave rhythm resonance and synchronize the sleep-related neural activities in the target nuclear area deep in the brain; The electroencephalogram acquisition device 11 is used to acquire the electroencephalogram signals of the user; The physiological state monitoring device 12 is used to obtain the physiological parameters of the user; The control device 10 is used to control and adjust the fundamental frequency, pulse width, pulse repetition frequency, difference frequency, and intensity of the two columns of ultrasonic waves generated by the acoustic wave emitting device according to the electroencephalogram signals and physiological parameters.

[0030] Among them, the acoustic wave emitting device includes: a signal generator 4, a power amplifier 3, and two ultrasonic generating devices 2. The signal generator 4 is used to generate an electrical excitation signal and control the two ultrasonic generating devices 2 to generate ultrasonic waves that meet the requirements; the power amplifier 3 is connected to the signal generator 4 and is used to amplify the electrical excitation signal; the two ultrasonic generating devices 2 are connected to the power amplifier 3 and are used to generate two columns of ultrasonic waves with similar frequencies and traveling in opposite directions.

[0031] Specifically, the signal generator 4 and the power amplifier 3 can be integrated in the pillow body 1 or can be external.

[0032] In this embodiment, the electroencephalogram acquisition device 11, the physiological state monitoring device 12, and the control device 10 are all connected to the signal generator 4, and the control device 10 is connected to the electroencephalogram acquisition device 11 and the physiological state monitoring device 12 to realize data circulation and transmission and a complete "perception-analysis-intervention" closed-loop regulation scheme.

[0033] The present invention provides an ultrasonic-infrasonic coupled acoustic wave whole-brain sleep regulation device, which achieves the purpose of helping sleep by guiding the rapid reduction of electroencephalogram rhythm; this technology is realized by generating two columns of ultrasonic waves with similar frequencies and traveling in opposite directions: in the volume range of 1-1000 cm 3In a 3D space, two columns of ultrasonic waves with similar frequencies (for example, one column of ultrasonic wave 7 (f1) that generates a beat phenomenon and another column of ultrasonic wave 8 (f2) that generates a beat phenomenon, f2 = f1 + Δf, where Δf < 100 Hz) are fed into the brain in opposite directions. Using the interference effect of sound waves, a low-frequency acoustic beat wave 9 with a frequency of Δf (range: 0.01 Hz - 100 Hz) is formed in the deep brain target nucleus area (such as the thalamic reticular nucleus, ventrolateral preoptic area), as Figure 2 , Figure 3 shown. This low-frequency acoustic beat wave can induce slow-wave rhythm resonance of electroencephalogram, synchronize sleep-related neural activities in the deep brain target nucleus area, and achieve coordinated regulation of the whole brain area.

[0034] Specifically, the ultrasonic wave generating device 2 that generates two columns of ultrasonic waves with similar frequencies and traveling in opposite directions should be placed on both sides of the brain, so that the deep brain nucleus area is in the middle of the two ultrasonic wave generating devices 2.

[0035] In one embodiment, the two ultrasonic wave generating devices 2 can be set at both ends of the pillow body 1. By changing the physical position and sound beam direction of the ultrasonic wave generating device 2, they can intersect in a specific brain area and generate infrasound. As Figure 1 shown, the user can lie on the groove 6, and the ultrasonic wave generating device 2 can also be set on the side wall 5 of the pillow. In this embodiment, the interaction relationship between the ultrasonic-infrasonic coupled sound wave and the brain is as Figure 3 shown. A low-frequency acoustic beat wave 9 with an infrasound frequency (Δf) oscillation is formed by one column of ultrasonic wave 7 that generates a beat phenomenon and another column of ultrasonic wave 8 that generates a beat phenomenon in the deep brain nucleus area. In addition, the two ultrasonic wave generating devices 2 can also be set on other forms of carriers such as helmets, and any shape of carrier integrating the ultrasonic wave generating device 2 is within the protection scope of this application.

[0036] In some embodiments, the ultrasonic waves generated by the two ultrasonic wave generating devices 2 include but are not limited to plane ultrasonic waves, line-focused ultrasonic waves, or point-focused ultrasonic waves, etc.

[0037] In some embodiments, the ultrasonic waves generated by the two ultrasonic wave generating devices 2 should propagate in opposite directions on the same straight line.

[0038] In some embodiments, the range of the low-frequency acoustic beat wave is 0.01 Hz - 100 Hz.

[0039] In some embodiments, the fundamental frequency range of the ultrasonic waves generated by the two ultrasonic wave generating devices 2 is 20 kHz - 10 MHz. And the intensities of the ultrasonic waves generated by the two ultrasonic wave generating devices 2 are within the national and international safety standards.

[0040] In some embodiments, the two ultrasonic wave generating devices 2 include but are not limited to ultrasonic transducers, etc.

[0041] In some embodiments, the sleep state monitoring part records the brain activity state (EEG) and physiological state (heart rate, respiratory rate, blood pressure, body movement parameters, etc.) of the user through various physiological acquisition sensors integrated on the pillow or other forms of implementation devices, judges the sleep state of the brain, and uses it as a feedback parameter to real-time control the output parameters of the ultrasonic-infrasonic combined sound wave. Among them, the output parameters of sleep state regulation include but are not limited to the fundamental frequency, pulse width, pulse repetition frequency, difference frequency, and intensity of the two ultrasonic waves.

[0042] In some embodiments, the sleep state regulation part is realized through a control device, a signal generator 4, and two ultrasonic generating devices 2. The output parameters of the ultrasonic-infrasonic combined sound wave are real-time controlled through the feedback of the sleep state, so as to realize the closed-loop dynamic regulation of "perception - analysis - intervention", and thus realize personalized sound wave stimulation, providing a new solution for the non-drug intervention of sleep disorders.

[0043] First, the two ultrasonic generating devices 2 are placed opposite to each other to emit two ultrasonic waves with similar frequencies, so that they can accurately stimulate the target brain area and generate beat frequency sound waves at the targeted position; second, by wearing the electroencephalogram acquisition device 11 and the physiological state monitoring device 12, collect and analyze the electroencephalogram state and related physiological parameters of the user, and use the analysis results as feedback information to real-time change the stimulation mode and related parameters of the ultrasonic generating device 2.

[0044] Specifically, the two ultrasonic waves emitted can be emitted simultaneously in the same phase or at different times with different phases; changing the stimulation mode of the two ultrasonic generating devices 2 through the feedback information includes changing the sound wave emission angle, overlapping position, targeted brain area, and related parameters (fundamental frequency, pulse width, pulse repetition frequency, difference frequency, intensity, etc.).

[0045] Among them, the collected electroencephalogram state and physiological parameters of the user can be used as feedback information to directly adjust the electrical excitation signal generated by the signal generator 4. By analyzing the electroencephalogram signal and related physiological parameters, the sleep state of the user is judged. If the analysis result is that the current user is in the falling asleep stage, the control device is used to adjust the signal generator parameters to control the transducer to emit low-intensity short-duration ultrasonic waves with the best resonance effect, so that the user can quickly enter the sleep state. If the analysis result is the primary sleep stage, the transducer is adjusted to emit medium-intensity long-duration ultrasonic waves with medium control effect, so as to stabilize the current state of the user and gradually enter the deep sleep state; a control device can also be added to the sound signal emission part to make it emit the required sound wave only at a specific time, so as to realize a real-time and personalized ultrasonic-infrasonic combined sound wave sleep aid solution.

[0046] Figure 4It is a flowchart of the whole-brain sleep regulation method using ultrasonic-infrasonic coupled sound waves shown in the embodiments of the present invention; when applying the whole-brain sleep regulation device using ultrasonic-infrasonic coupled sound waves described in this embodiment, the following steps can be executed: Collect the electroencephalogram (EEG) signals of the user using an EEG acquisition device; Obtain the physiological parameters of the user using a physiological state monitoring device; Use a control device to control and adjust parameters such as the fundamental frequency, pulse width, pulse repetition frequency, difference frequency, and intensity of the two ultrasonic waves generated by the acoustic wave emission device according to the EEG signals and physiological parameters; Use the acoustic wave emission device to generate and emit two ultrasonic waves with similar frequencies and traveling in opposite directions, feed the two ultrasonic waves into the brain in opposite directions, and the two ultrasonic wave signals inhibit the activity of the cerebral cortex when passing through the cerebral cortex; at the same time, they meet and interfere in the deep brain target nucleus area to form low-frequency infrasonic beat waves, so as to induce EEG slow wave rhythm resonance and synchronize the sleep-related neural activities in the deep brain target nucleus area.

[0047] The above are only the preferred embodiments of the present invention and are not used to limit the present invention. For those skilled in the art, the present invention can have various changes and modifications. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. An ultrasonic-infrasonic coupled acoustic wave-based whole-brain sleep regulation device, characterized in that, Comprising: A pillow body, and a sound wave emitting device, an electroencephalogram (EEG) acquisition device, a physiological state monitoring device, and a control device disposed within the pillow body, wherein the control device is connected to the sound wave emitting device, the EEG acquisition device, and the physiological state monitoring device; The sound wave emitting device is configured to generate and emit two ultrasonic waves with similar frequencies and traveling in opposite directions, feed the two ultrasonic waves into the brain in opposite directions, and suppress the activity of the cerebral cortex when the two ultrasonic wave signals pass through the cerebral cortex; at the same time, the two ultrasonic wave signals interfere with each other when they meet in the target nucleus area deep in the brain, forming a low-frequency acoustic beat wave to induce EEG slow wave rhythm resonance and synchronize the sleep-related neural activities in the target nucleus area deep in the brain; The EEG acquisition device is configured to acquire the EEG signals of the user; The physiological state monitoring device is configured to obtain the physiological parameters of the user; The control device is configured to control and adjust the fundamental frequency, pulse width, pulse repetition frequency, difference frequency, and intensity of the two ultrasonic waves generated by the sound wave emitting device according to the EEG signals and the physiological parameters.

2. The whole-brain sleep regulation device for ultrasonic-infrasonic coupled sound waves according to claim 1, wherein The sound wave emitting device includes: a signal generator, a power amplifier, and two ultrasonic generating devices; The signal generator is configured to generate an electrical excitation signal and control the two ultrasonic generating devices to generate ultrasonic waves meeting the requirements; The power amplifier is connected to the signal generator and configured to amplify the electrical excitation signal; The two ultrasonic generating devices are connected to the power amplifier and configured to generate two ultrasonic waves with similar frequencies and traveling in opposite directions.

3. The whole-brain sleep regulation device using ultrasonic-infrasonic coupled sound waves according to claim 2, characterized in that The low-frequency acoustic beat wave is obtained by superimposing and interfering the ultrasonic waves generated by the two ultrasonic generating devices.

4. The whole-brain sleep regulation device for ultrasonic-infrasonic coupled sound waves according to claim 2, characterized in that, The fundamental frequency range of the ultrasonic waves generated by the two ultrasonic generating devices is 20 kHz - 10 MHz.

5. The whole-brain sleep regulation device for ultrasonic-infrasonic coupled sound waves according to claim 2, wherein The low-frequency acoustic beat wave is formed by superimposing and interfering two ultrasonic waves with similar frequencies and traveling in opposite directions, and the frequency difference range is 0.01 Hz - 100 Hz.

6. The whole-brain sleep regulation device for ultrasonic-infrasonic coupled sound waves according to claim 2, wherein The ultrasonic waves generated by the two ultrasonic generating devices propagate in opposite directions on the same straight line.

7. The whole-brain sleep regulation device for ultrasonic-infrasonic coupled sound waves according to claim 2, wherein The two ultrasonic generating devices are symmetrically arranged at both ends of the pillow body, so that the ultrasonic waves generated by the two devices propagate on the same straight line and form a low-frequency acoustic beat wave in the target deep brain area.

8. The whole-brain sleep regulation device for ultrasonic-infrasonic coupled sound waves according to claim 2, characterized in that, The ultrasonic waves generated by the two ultrasonic generating devices include plane ultrasonic waves, line-focused ultrasonic waves, or point-focused ultrasonic waves.

9. The whole-brain sleep regulation device for ultrasonic-infrasonic coupled sound waves according to any one of claims 1-8, characterized in that, The two ultrasonic generating devices include ultrasonic transducers.

10. A method for regulating whole-brain sleep by ultrasonic-infrasonic coupled sound waves, characterized in that, An ultrasonic-infrasonic coupled sound wave-based whole-brain sleep regulation device according to any one of claims 1 - 9, comprising: Using an EEG acquisition device to acquire the EEG signals of the user; Using a physiological state monitoring device to obtain the physiological parameters of the user; Using a control device to control and adjust the fundamental frequency, pulse width, pulse repetition frequency, difference frequency, and intensity of the two ultrasonic waves generated by the sound wave emitting device according to the EEG signals and the physiological parameters; Using a sound wave emitting device to generate and emit two ultrasonic waves with similar frequencies and traveling in opposite directions, feed the two ultrasonic waves into the brain in opposite directions, and suppress the activity of the cerebral cortex when the two ultrasonic wave signals pass through the cerebral cortex; at the same time, the two ultrasonic wave signals interfere with each other when they meet in the target nucleus area deep in the brain, forming a low-frequency acoustic beat wave to induce EEG slow wave rhythm resonance and synchronize the sleep-related neural activities in the target nucleus area deep in the brain.

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