Composition containing spider silk hydrolysate and application thereof

Abstract

The invention discloses a composition containing spider silk hydrolysate. The composition is prepared from the following raw materials in parts by weight: 25-35 parts of spider silk hydrolysate, 15-20 parts of cinnamon leaf residue extracting solution, 2-6 parts of lotus extracting solution, 3-7 parts of stearyl alcohol, 5-9 parts of glycerol, 2-6 parts of palmitoyl tripeptide and 14 parts of stearyl glucoside. The invention further provides application of the composition containing the spider silk hydrolysate in preparation of anti-aging drugs or skin care products. According to the composition of the spider silk hydrolysate, the anti-aging effect is improved, the added stearyl alcohol, glycerol, palmitoyl tripeptide and stearyl glucoside are used as auxiliary materials to be applied to anti-aging drugs or skin care products, the good anti-aging curative effect is achieved, the increase rate of the skin moisture content of the products can be improved due to the addition of the spider silk hydrolysate, and the anti-aging effect of the products is improved. And meanwhile, the anti-aging effect of the product can be stabilized, and the raw materials are matched with one another, so that a remarkable improvement effect is achieved.

Description

Technical Field

[0001] The present invention relates to the technical field of spider silk composite materials, and particularly relates to a composition containing spider silk hydrolyzate and its application. Background Art

[0002] Spider silk is a natural animal protein fiber, containing multiple repeated polypeptide sequences such as (GPGXX)n / (GPGQQ)n, An / (GA)n, (GGX)n, etc.; it has excellent mechanical properties and characteristics that are incomparable to other synthetic high-performance fibers, such as high strength, good elasticity, high initial modulus, high breaking energy, biodegradability, good biocompatibility, good moisturizing property, and lightness. Traditional Chinese medicine believes that spider silk has the following properties: slightly cold in nature. Meridian tropism: Liver meridian. Functions and indications: stopping bleeding; removing warts. Mainly used for treating hematemesis; bleeding from metal wounds; warts; blood tumors; hemorrhoids and fistulas. Spider silk is rich in amino acids, and its hydrolyzate is rich in nutrients, and at the same time has the functions of antioxidant, enhancing immunity, and anti-inflammatory and hemostatic.

[0003] The existing compositions of spider silk hydrolyzate are generally conventional, with simple compounding effects and poor anti-aging effects. At the same time, the application effects on cosmetics are not very good. Patent CN201711090964.X provides a cosmetic containing spider silk hydrolyzate and its preparation method. However, this cosmetic has complex ingredients, a low content of spider silk hydrolyzate, and ingredients such as glycerol and hyaluronic acid are added. Therefore, it is difficult to clarify the effects of spider silk hydrolyzed components in it. Summary of the Invention

[0004] Aiming at the defects of the existing technology, the purpose of the present invention is to provide a composition containing spider silk hydrolyzate and its application to solve the problems raised in the above background art.

[0005] The present invention adopts the following technical solutions to solve the above technical problems:

[0006] The present invention provides a composition containing spider silk hydrolyzate, which includes the following raw materials by weight:

[0007] 25 - 35 parts of spider silk hydrolyzate, 15 - 20 parts of cinnamon leaf residue extract, 2 - 6 parts of lotus flower extract, 3 - 7 parts of stearyl alcohol, 5 - 9 parts of glycerol, 2 - 6 parts of palmitoyl tripeptide, 1 - 4 parts of stearyl glucoside.

[0008] Preferably, the above composition includes the following raw materials by weight:

[0009] 30 parts of spider silk hydrolyzate, 17.5 parts of cinnamon leaf residue extract, 4 parts of lotus flower extract, 5 parts of stearyl alcohol, 7 parts of glycerol, 4 parts of palmitoyl tripeptide, 2.5 parts of stearyl glucoside.

[0010] Preferably, the method for preparing the spider silk hydrolysate comprises the following steps:

[0011] S101: crushing the spider silk, and then hydrolyzing it in a 5% sodium hydroxide aqueous solution with a mass fraction of 3-5 times the weight thereof to obtain a hydrolyzed material;

[0012] S102: mixing carbon nanotubes and attapulgite in a weight ratio of 3:1, and then grinding and passing through a 350-450 mesh to obtain a composite material;

[0013] S103: sending the composite material obtained in S102 into a modification liquid of 2-3 times the weight thereof for modification treatment to obtain a modified composite material;

[0014] S104: The modified composite material and the hydrolyzed material are mixed in a weight ratio of 1:3, and the mixture is mixed thoroughly to obtain spider silk hydrolyzate.

[0015] Preferably, the preparation method of the modified liquid in S103 is: by weight, add 1-5 parts of hexadecyltrimethylammonium bromide, 1-3 parts of

[0016] The coupling agent is added, and finally 3-6 parts of hydrochloric acid with a mass fraction of 5% are added and mixed thoroughly to obtain a modified solution. The modification temperature in the modification treatment in S103 is 65-75°C, the modification speed is 450-550r / min, the modification time is 35-45min, and after the modification is completed, the modification is washed with water and dried. The coupling agent is y-aminopropyltriethoxysilane.

[0017] Preferably, the preparation method of the cinnamon leaf residue extract is:

[0018] The cinnamon leaf residue is sent to an ethanol aqueous solution with a mass fraction of 75-85% and a weight of 2-3 times the weight to extract, then centrifuged, filtered, and then dealcoholized to obtain a cinnamon leaf residue extract. The ethanol extraction temperature is 82-85° C., and the extraction treatment is carried out at 0.5-0.7 MPa for 1-2 hours.

[0019] Preferably, the method for extracting the lotus extract comprises the following steps:

[0020] S111: by weight, 20-30 parts of lotus are added to 45-55 parts of water for pulping;

[0021] S112: adding 3-5% by mass of cellulase and performing enzymolysis at 35-40° C. for 10-20 min;

[0022] S113: Boil in 2-3 times the weight of water for 25-35 minutes, and obtain lotus extract after boiling.

[0023] Preferably, the boiling in S113 is carried out with gentle fire and coupled combined treatment at the same time; the coupled combined treatment is a magnetic field intensity of 40 - 60 Bt, an ultrasonic power of 100 - 200 W, and magnetic field and ultrasonic treatment for 10 - 20 min.

[0024] The present invention also provides an application of a composition containing spider silk hydrolysate in the preparation of a drug or skin care product with anti - aging effect.

[0025] Compared with the prior art, the present invention has the following beneficial effects:

[0026] For the composition of spider silk hydrolysate of the present invention, the extract of cinnamon leaf residue and the extract of lotus flower are used as the main anti - aging combination agents to improve the anti - aging effect. The added stearyl alcohol, glycerol, palmitoyl tripeptide, and stearyl glucoside are used as added auxiliary materials. When applied in a drug or skin care product with anti - aging effect, it has a good anti - aging effect. The addition of spider silk hydrolysate can improve the growth rate of skin water content, enhance the efficiency of improving skin water content, and at the same time can stabilize the anti - aging effect of the product. The raw materials are combined with each other, showing a significant improvement effect. Detailed implementation manners

[0027] The following combines specific embodiments to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all of them. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts belong to the scope of protection of the present invention.

[0028] Embodiment 1

[0029] A composition containing spider silk hydrolysate in this embodiment includes the following raw materials in parts by weight:

[0030] 25 parts of spider silk hydrolysate, 15 parts of extract of cinnamon leaf residue, 2 parts of extract of lotus flower, 3 parts of stearyl alcohol, 5 parts of glycerol, 2 parts of palmitoyl tripeptide, and 1 part of stearyl glucoside.

[0031] The preparation method of the spider silk hydrolysate in this embodiment is as follows:

[0032] S101: Feed the spider silk into a pulverizer for pulverization, and then carry out hydrolysis treatment in an aqueous sodium hydroxide solution with a mass fraction of 5% and a weight 3 times that of the spider silk. After the hydrolysis is completed, a hydrolyzed material is obtained;

[0033] S102: Mix carbon nanotubes and attapulgite in a weight ratio of 3:1, then feed them into a grinder for grinding, and pass through a 350 - mesh sieve to obtain a composite material;

[0034] S103: The composite material is fed into the modification liquid with a weight twice that of the composite material for modification treatment. The modification temperature is 65 °C, the modification rotation speed is 450 r / min, and the modification time is 35 min. After the modification is completed, it is washed with water and dried to obtain the modified composite material;

[0035] S104: The modified composite material and the hydrolyzed material are mixed in a weight ratio of 1:3 and mixed thoroughly to obtain the spider silk hydrolyzate.

[0036] The preparation method of the modification liquid in this example is as follows: By weight, 1 part of cetyltrimethylammonium bromide and 1 part of coupling agent are added to 10 parts of an aqueous sodium alginate solution with a mass fraction of 5%, and finally 3 parts of hydrochloric acid with a mass fraction of 5% are added, and they are mixed thoroughly to obtain the modification liquid.

[0037] The coupling agent in this example is γ-aminopropyltriethoxysilane.

[0038] The preparation method of the cinnamon leaf residue extract in this example is as follows:

[0039] The cinnamon leaf residue is fed into an aqueous ethanol solution with a mass fraction of 75% and a weight twice that of the residue for extraction for 1 h. After the extraction is completed, it is centrifuged and filtered, and then the alcohol is removed to obtain the cinnamon leaf residue extract.

[0040] The extraction temperature of the aqueous ethanol solution extraction in this example is 82 °C, and the extraction treatment is carried out at 0.5 MPa.

[0041] The extraction method of the lotus flower extract in this example is as follows:

[0042] S111: By weight, 20 parts of lotus flowers are added to 45 parts of water for pulping treatment;

[0043] S112: Then 3% by weight of cellulase is added and enzymolyzed at 35 °C for 10 min;

[0044] S113: Then it is boiled in water with a weight twice that of the lotus flower extract for 25 min. After the boiling is completed, the lotus flower extract is obtained.

[0045] In this example, the boiling is carried out with a gentle fire and a coupling treatment is adopted simultaneously;

[0046] The coupling treatment is a magnetic field intensity of 40 Bt, an ultrasonic power of 100 W, and magnetic field and ultrasonic treatment for 10 min.

[0047] The application of a composition containing spider silk hydrolyzate in this example in the preparation of drugs or skin care products with anti-aging effects.

[0048] Example 2

[0049] A composition containing spider silk hydrolyzate in this example includes the following raw materials in parts by weight:

[0050] 35 parts of spider silk hydrolyzate, 20 parts of cinnamon leaf residue extract, 6 parts of lotus flower extract, 7 parts of stearyl alcohol, 9 parts of glycerin, 6 parts of palmitoyl tripeptide, 4 parts of stearyl glucoside.

[0051] The preparation method of the spider silk hydrolyzate in this example is as follows:

[0052] S101: Feed the spider silk into a crusher for crushing, and then carry out hydrolysis treatment with 5 times the weight of a 5% sodium hydroxide aqueous solution. After the hydrolysis is completed, a hydrolyzed material is obtained;

[0053] S102: Mix carbon nanotubes and attapulgite in a weight ratio of 3:1, and then feed them into a grinder for grinding. Pass through a 450-mesh sieve to obtain a composite material;

[0054] S103: Feed the composite material into 3 times the weight of a modification liquid for modification treatment. The modification temperature is 75 °C, the modification rotation speed is 550 r / min, and the modification time is 45 min. After the modification is completed, wash with water and dry to obtain a modified composite material;

[0055] S104: Mix the modified composite material and the hydrolyzed material in a weight ratio of 1:3 and mix well to obtain the spider silk hydrolyzate.

[0056] The preparation method of the modification liquid in this example is as follows: By weight, add 5 parts of cetyltrimethylammonium bromide and 3 parts of coupling agent to 20 parts of a 5% sodium alginate aqueous solution, and finally add 6 parts of a 5% hydrochloric acid, mix well to obtain the modification liquid.

[0057] The coupling agent in this example is γ-aminopropyltriethoxysilane.

[0058] The preparation method of the cinnamon leaf residue extract in this example is as follows:

[0059] Feed the cinnamon leaf residue into 3 times the weight of an 85% ethanol aqueous solution for extraction for 2 h. After the extraction is completed, carry out centrifugation and filtration, and then remove alcohol to obtain the cinnamon leaf residue extract.

[0060] The extraction temperature of the ethanol aqueous solution extraction in this example is 85 °C, and the extraction treatment is carried out at 0.7 MPa.

[0061] The extraction method of the lotus flower extract in this example is as follows:

[0062] S111: By weight, add 30 parts of lotus flower to 55 parts of water for pulping treatment;

[0063] S112: Then add 5% cellulase by weight and carry out enzymatic hydrolysis at 40 °C for 20 min;

[0064] S113: Then boil the mixture in water three times its weight for 35 minutes, and the lotus extract is obtained after the boiling is completed.

[0065] The boiling of this embodiment adopts slow fire boiling, and adopts coupling joint processing at the same time;

[0066] The coupling treatment is as follows: the magnetic field intensity is 60Bt, the ultrasonic power is 200W, and the magnetic field and ultrasonic treatment are carried out for 20 minutes.

[0067] The present embodiment provides an application of a spider silk hydrolyzate-containing composition in the preparation of an anti-aging drug or skin care product.

[0068] Example 3

[0069] A composition containing spider silk hydrolyzate of this embodiment includes the following raw materials in parts by weight:

[0070] 30 parts of spider silk hydrolyzate, 17.5 parts of cinnamon leaf residue extract, 4 parts of lotus extract, 5 parts of stearyl alcohol, 7 parts of glycerin, 4 parts of palmitoyl tripeptide, and 2.5 parts of stearyl glucoside.

[0071] The preparation method of the spider silk hydrolyzate of this embodiment is:

[0072] S101: feeding the spider silk into a pulverizer and pulverizing it, and then hydrolyzing it in a 5% sodium hydroxide aqueous solution having a mass fraction of 4 times the weight thereof, until the hydrolysis is completed, a hydrolyzed material is obtained;

[0073] S102: mixing carbon nanotubes and attapulgite in a weight ratio of 3:1, and then feeding them into a grinder for grinding, passing through a 400 mesh, to obtain a composite material;

[0074] S103: the composite material is sent into a modification liquid with a weight of 2.5 times the weight thereof for modification treatment. The modification temperature is 70°C, the modification speed is 500r / min, and the modification time is 40min. After the modification is completed, the composite material is washed with water and dried to obtain a modified composite material.

[0075] S104: The modified composite material and the hydrolyzed material are mixed in a weight ratio of 1:3, and the mixture is mixed thoroughly to obtain a spider silk hydrolyzate.

[0076] The preparation method of the modified liquid of this embodiment is as follows: by weight, 3 parts of hexadecyltrimethylammonium bromide and 2 parts of coupling agent are added to 15 parts of 5% sodium alginate aqueous solution, and finally 4.5 parts of 5% hydrochloric acid are added, and mixed thoroughly to obtain the modified liquid.

[0077] The coupling agent of this embodiment is y-aminopropyltriethoxysilane.

[0078] The preparation method of the cinnamon leaf residue extract of the present embodiment is:

[0079] The cinnamon leaf residue is sent to 2.5 times the weight of 80% ethanol aqueous solution for extraction for 1.5 hours. After the extraction is completed, centrifugation, filtration and dealcoholization are performed to obtain the cinnamon leaf residue extract.

[0080] The extraction temperature of the ethanol aqueous solution extraction in this embodiment is 83.5° C., and the extraction process is carried out at 0.6 MPa.

[0081] The extraction method of the lotus extract of the present embodiment is:

[0082] S111: by weight, 25 parts of lotus are added to 50 parts of water for pulping;

[0083] S112: then adding 4% by weight of cellulase and performing enzymolysis at 37° C. for 15 min;

[0084] S113: Then boil the mixture in 2.5 times the weight of water for 30 minutes, and the lotus extract is obtained after the boiling is completed.

[0085] The boiling of this embodiment adopts slow fire boiling, and adopts coupling joint processing at the same time;

[0086] The coupling treatment is performed with a magnetic field intensity of 50 Bt, an ultrasonic power of 150 W, and a magnetic field and ultrasonic treatment for 15 minutes.

[0087] The present embodiment provides an application of a spider silk hydrolyzate-containing composition in the preparation of an anti-aging drug or skin care product.

[0088] Comparative Example 1

[0089] The difference from Example 3 is that no spider silk hydrolyzate was added.

[0090] Comparative Example 2

[0091] The difference from Example 3 is that in the preparation of spider silk hydrolyzate, carbon nanotubes and attapulgite are replaced by talcum powder and pearl powder.

[0092] Comparative Example 3

[0093] The difference from Example 3 is that the preparation of the modified liquid in the method for preparing spider silk hydrolyzate is different;

[0094] The preparation method of the modified liquid is as follows: 3 parts of tartaric acid and 2 parts of sodium hepatocholate are added to 15 parts of 5% by mass dioctyl sodium sulfosuccinate aqueous solution, and finally 4.5 parts of 5% by mass hydrochloric acid are added, and the mixture is mixed thoroughly to obtain the modified liquid.

[0095] Comparative Example 4

[0096] The difference from Example 3 is that no lotus extract was added.

[0097] Comparative Example 5

[0098] Different from Example 3, coupling combined treatment was not used in the extraction of lotus extract.

[0099] Comparative Example 6

[0100] Different from Example 3, the lotus in the lotus extract was replaced with plantain seeds.

[0101] To compare and illustrate the performance of different products, the following performances of the products obtained in the examples and comparative examples were tested, and the test results are as follows.

[0102] The products of Examples 1-3 and Comparative Examples 1-6 were tested after being used for 8 weeks.

[0103] Test Example 1

[0104] Provided by a beauty hospital in Hubei, and 90 female volunteers aged 25-45 were selected to participate in the experiment. They were randomly divided into 9 groups: Experimental Group 1 - Experimental Group 9. Each experimental group used the product corresponding to the example, once on the arm every morning and evening for a total of 8 weeks, and the elastic index of the product after use was detected by an MPA580 elasticity detector. The volunteers before using the product were used as a control. The skin surface layer of the volunteers before and after using the product was collected by the tape stripping method. The tape was soaked in PBS buffer solution, ultrasonically extracted for 10 minutes, and the supernatant was taken by centrifugation. A hydroxyl radical fluorescence probe was added, and the ability of the product to scavenge hydroxyl radicals was detected by a fluorescence microplate reader. The products of the examples and comparative examples were dissolved in PBS and mixed with DPPH solution, and incubated in the dark. The antioxidant ability of the product solution to DPPH was directly tested by a microplate reader.

[0105] The performance test results of the products of Examples 1-3 and Comparative Examples 1-6 are as follows:

[0106]

[0107] It can be seen from Comparative Examples 1-6 and Example 3 that:

[0108] The DPPH and hydroxyl radical scavenging rates of Example 3 of the present invention have significant improvement effects, and the skin elasticity index also reaches the best state. It can be seen from Comparative Example 1 that without adding spider silk hydrolysate, the DPPH, hydroxyl radical scavenging rates and skin elasticity index performance of the product show a downward trend, but the improvement effect is not as obvious as that of adding lotus extract. In addition, compared with the spider silk hydrolysate of the spider silk provided by the method of the present invention, the antioxidant index, free radical scavenging rate index, etc. of the spider silk hydrolysate obtained by other preparation methods all decrease.

[0109] Skin moisture content test:

[0110] Water content tests were conducted after 1 week, 5 weeks, and 10 weeks of using this product:

[0111] Test Example 2

[0112] Provided by a beauty hospital in Hubei, 90 female volunteers aged 25 - 45 were selected and randomly divided into 9 groups: Test Group 1 - Test Group 9. Each test group used the product of the corresponding example and applied it once on the arm every morning and evening. The Corneometer CM825 was used to detect the water content of the arm skin after using the product for 1 week, 5 weeks, and 10 weeks.

[0113]

[0114] From the skin water content tests after 1 week, 5 weeks, and 10 weeks of the product:

[0115] Since the spider silk hydrolyzate was not added in the present invention, the growth rate of water content decreased significantly. In Comparative Example 1, from the data of 56.1%, 61.3%, and 68.4% in 1 week, 5 weeks, and 10 weeks, it can be seen that the growth trend of water content was poor.

[0116] However, the addition of lotus extract had a greater influence on the amount of skin water content. In Comparative Example 4, in the first week, without the addition of lotus extract, the water content decreased significantly, but the influence trend on the growth rate of water content in 5 weeks and 10 weeks was not as effective as that of spider silk hydrolyzate.

[0117] The addition of spider silk hydrolyzate can improve the growth rate of the product's skin water content and enhance the water improvement efficiency of the skin. While the lotus extract can increase the skin water content and provide a basic guarantee for skin water content. At the same time, different preparation methods of spider silk hydrolyzate are not as good as the preparation of the present invention in terms of improving the product performance.

[0118] Test Example 3

[0119] To evaluate the influence of high temperature on the product performance stability. First, the products of Examples 1 - 3 and Comparative Examples 1 - 6 were placed at 55 °C for 1 day, and then the product performance was detected according to the method of Test Example 1.

[0120]

[0121]

[0122] It was found that after the products were placed at 55 °C for 1 day, without the addition of spider silk hydrolyzate, the product performance decreased significantly. But without the addition of lotus extract, the deterioration effect was not obvious. Spider silk hydrolyzate has a significant improvement on the product performance stability. At the same time, different preparation methods of spider silk hydrolyzate have different performance effects, but none of them is as significantly improved as the preparation method of the present invention.

[0123] For those skilled in the art, it is obvious that the present invention is not limited to the details of the above-described exemplary embodiments, and the present invention can be implemented in other specific forms without departing from the spirit or basic characteristics of the present invention. Therefore, from any point of view, the embodiments should be regarded as exemplary and non-limiting. The scope of the present invention is defined by the appended claims rather than the above description. Therefore, all changes falling within the meaning and scope of the equivalent elements of the claims are intended to be embraced within the present invention.

[0124] In addition, it should be understood that although this specification is described according to embodiments, not every embodiment only contains an independent technical solution. This narrative manner of the specification is only for clarity. Those skilled in the art should regard the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A composition containing spider silk hydrolysate, characterized in that, Including the following ingredients: 25-35 parts of spider silk hydrolyzate, 15-20 parts of cinnamon leaf residue extract, 2-6 parts of lotus extract, 3-7 parts of stearyl alcohol, 5-9 parts of glycerol, 2-6 parts of palmitoyl tripeptide, and 1-4 parts of stearyl glucoside.

2. The composition containing spider silk hydrolyzate according to claim 1, wherein: The following raw materials are included in parts by weight: 30 parts of spider silk hydrolyzate, 17.5 parts of cinnamon leaf residue extract, 4 parts of lotus extract, 5 parts of stearyl alcohol, 7 parts of glycerin, 4 parts of palmitoyl tripeptide, and 2.5 parts of stearyl glucoside.

3. A composition containing spider silk hydrolyzate according to claim 1 or 2, characterized in that The method for preparing the spider silk hydrolysate comprises the following steps: S101: crushing the spider silk, and then hydrolyzing it in a 5% sodium hydroxide aqueous solution with a mass fraction of 3-5 times the weight to obtain a hydrolyzed material; S102: mixing carbon nanotubes and attapulgite in a weight ratio of 3:1, and then grinding and passing through a 350-450 mesh to obtain a composite material; S103: sending the composite material obtained in S102 into a modification liquid of 2-3 times the weight thereof for modification treatment to obtain a modified composite material; S104: The modified composite material and the hydrolyzed material are mixed in a weight ratio of 1:3, and the mixture is mixed thoroughly to obtain spider silk hydrolyzate.

4. A composition containing spider silk hydrolyzate according to claim 3, characterized in that: The preparation method of the modified liquid in S103 is: by weight, add 1-5 parts of hexadecyltrimethylammonium bromide and 1-3 parts of coupling agent to 10-20 parts of 5% sodium alginate aqueous solution, and finally add 3-6 parts of 5% hydrochloric acid, mix well, and obtain the modified liquid.

5. A composition containing spider silk hydrolyzate according to claim 4, characterized in that: The modification temperature in the modification treatment in S103 is 65-75° C., the modification speed is 450-550 r / min, the modification time is 35-45 min, and after the modification is completed, the material is washed with water and dried.

6. The composition containing spider silk hydrolyzate according to claim 4, characterized in that: The coupling agent is y-aminopropyltriethoxysilane.

7. A composition containing spider silk hydrolyzate according to claim 3, characterized in that: The preparation method of the cinnamon leaf residue extract is: The cinnamon leaf residue is sent to an ethanol aqueous solution with a mass fraction of 75-85% and a weight of 2-3 times the weight thereof for extraction, and then centrifuged, filtered, and then dealcoholized to obtain a cinnamon leaf residue extract; the ethanol extraction temperature is 82-85° C., and the extraction treatment is carried out at 0.5-0.7 MPa for 1-2 hours.

8. The composition containing spider silk hydrolyzate according to claim 3, characterized in that: The method for extracting the lotus extract comprises the following steps: S111: by weight, 20-30 parts of lotus are added to 45-55 parts of water for pulping; S112: adding 3-5% by mass of cellulase and performing enzymolysis at 35-40° C. for 10-20 min; S113: Boil in 2-3 times the weight of water for 25-35 minutes, and obtain lotus extract after boiling.

9. A composition containing spider silk hydrolyzate according to claim 8, characterized in that: The boiling in S113 is performed over a low heat, and coupled combined treatment is performed at the same time; the coupled combined treatment is performed with a magnetic field intensity of 40-60Bt, an ultrasonic power of 100-200W, and the magnetic field and ultrasonic treatment are performed for 10-20min.

10. Use of a composition containing spider silk hydrolyzate according to any one of claims 1 to 9 in the preparation of anti-aging drugs or skin care products.

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