Composite tablet candy with hangover alleviating function and preparation method of composite tablet candy

Abstract

The invention relates to the technical field of hangover alleviating food processing, in particular to a compound tabletted candy with a hangover alleviating function and a preparation method of the compound tabletted candy. The composite tablet candy is prepared from the following components in parts by weight: 30-40 parts of radix puerariae, 20-30 parts of semen hoveniae, 8-16 parts of mulberries, 5-15 parts of pericarpium citri reticulatae, 5-15 parts of poria cocos, 2-6 parts of fresh ginger, 2-6 parts of dendrobium nobile, 1-5 parts of rhizoma polygonati, 15-25 parts of maltose extract and 1-3 parts of a taste modifier, and is prepared by the following steps: cleaning the raw materials, mixing and crushing, granulating, drying and granulating, tabletting and packaging. The compound tabletted candy with the function of dispelling the effects of alcohol is prepared. In the invention, the composite tablet candy is prepared by compounding eight natural Chinese herbal medicines with addition of maltodextrin, mint extract and vitamin C, the raw materials comprehensively improve discomfort after drinking through a multi-target synergistic effect of'dispelling the effects of alcohol, protecting the stomach, tonifying the spleen and nourishing yin ', and meanwhile, the composite tablet candy has a sour, sweet and cold mouth feel of dietary fruits when being eaten, and is suitable for being eaten by people. The eating experience of the Chinese herbal medicine compound tablet candy is effectively improved.

Description

Technical Field

[0001] The present invention relates to the technical field of hangover food processing, and in particular to a compound tablet candy with hangover function and a preparation method thereof. Background Art

[0002] As the name implies, hangover means sobering up from drunkenness, which refers to quickly decomposing and metabolizing the alcohol in the body before and after getting drunk, so that people can wake up from the drunken state. Generally, it can be divided into natural hangover (the natural metabolism of alcohol in the human body without taking any artificial methods) and assisted hangover (helping to relieve the hangover through external methods).

[0003] In modern social scenarios, excessive drinking is likely to cause discomfort symptoms such as headache, nausea, and liver damage. At present, most of the hangover products on the market are mainly composed of chemically synthesized components (such as naloxone hydrochloride, acetyl-L-cysteine, or naloxone, etc.) or single traditional Chinese medicine extracts (such as kudzu root powder, curcumin, or schisandrin, etc.). However, these two forms of hangover products have the following deficiencies in the actual use process of users: First, long-term use of chemically synthesized components may produce side effects; Second, the hangover effect of a single raw material is limited, and it cannot take into account multiple needs such as protecting the liver and stomach; Third, the taste of traditional tablets is poor, and the acceptance of consumers is low.

[0004] In view of this, it is particularly important to develop and manufacture a compound tablet candy that is natural, safe, has synergistic effects, and has a good taste, and is applied to the scenario of quickly relieving the hangover of users. Summary of the Invention

[0005] The purpose of the present invention is: aiming at the deficiencies of existing hangover products, the present invention provides a compound tablet candy with homologous medicine and food raw materials as the core, which realizes the synergistic effects of hangover, protecting the liver, and protecting the stomach through the scientific ratio of raw material components, and at the same time has good taste and formability, and thus provides a compound tablet candy with hangover function and a preparation method thereof.

[0006] In order to achieve the above purpose, the present invention adopts the following technical scheme: A compound tablet candy with hangover function, comprising the following components: 30-40 parts of kudzu root, 20-30 parts of oriental raisin tree seed, 8-16 parts of mulberry, 5-15 parts of tangerine peel, 5-15 parts of poria cocos, 2-6 parts of ginger, 2-6 parts of dendrobium officinale, 1-5 parts of polygonatum sibiricum, 15-25 parts of maltodextrin, and 1-3 parts of taste improver.

[0007] As a further description of the above technical scheme: 30 parts of kudzu root, 20 parts of oriental raisin tree seed, 8 parts of mulberry, 5 parts of tangerine peel, 5 parts of poria cocos, 2 parts of ginger, 2 parts of dendrobium officinale, 1 part of polygonatum sibiricum, 15 parts of maltodextrin, and 1 part of taste improver.

[0008] As a further description of the above technical solution: The said kudzu root is 35 parts,hovenia dulcis is 25 parts, mulberry is 12 parts, dried tangerine peel is 10 parts, poria cocos is 10 parts, ginger is 4 parts, dendrobium officinale is 4 parts, polygonatum sibiricum is 3 parts, maltodextrin is 20 parts and taste improver is 2 parts.

[0009] As a further description of the above technical solution: The said kudzu root is 40 parts, hovenia dulcis is 30 parts, mulberry is 16 parts, dried tangerine peel is 15 parts, poria cocos is 15 parts, ginger is 6 parts, dendrobium officinale is 6 parts, polygonatum sibiricum is 5 parts, maltodextrin is 25 parts and taste improver is 3 parts.

[0010] As a further description of the above technical solution: The said taste improver is a mixture of mint extract and vitamin C in a mass ratio of 2:1.

[0011] A preparation method of a compound tablet candy with hangover function, which comprises the following steps: S100, raw material cleaning: Weigh kudzu root, hovenia dulcis, mulberry, dried tangerine peel, poria cocos, ginger, dendrobium officinale and polygonatum sibiricum according to the above formula composition requirements, clean them respectively by an ultrasonic cleaner for three minutes, then drain the water and carry out drying treatment for later use; S200, mixing and pulverizing: Pour the cleaned and dried medicinal materials in the previous step into a medicinal material pulverizer, pulverize continuously twice, control the pulverizing time for each time to be 5 - 15 minutes, and then screen the mixed powder through an 80 - mesh sieve to obtain mixed medicinal powder; S300, granulation processing: Mix the mixed medicinal powder obtained in the previous step with the taste improver according to the formula component requirements, then centrally add it to a wet granulator, use an ethanol solution with a volume fraction of 60% as a wetting agent for granulation treatment, and then screen the granulated particles through a 20 - mesh sieve to obtain wet mixed particles; S400, drying and sizing: Add the mixed particles obtained in the previous step to a fluidized bed dryer for drying treatment. When the moisture content of the mixed particles ≤ 3%, screen them through a 16 - mesh sieve to obtain dry mixed particles; S500, tabletting processing: Mix the dry mixed particles obtained after drying and sizing with maltodextrin according to the formula component requirements, then centrally add it to a V - type mixer for mixing treatment, and add the mixed mixture to a tabletting machine for tabletting treatment, control the tablet weight to be 0.5 g / tablet, and finally obtain compound tablet candy; S600, packaging: According to the actual processing requirements, carry out packaging and sealing treatment on the compound tablet candy by means of bottling, bagging or blister pressing plate packaging.

[0012] As a further description of the above technical solution: In step S100, the washed medicinal materials can be dried by sun drying, air drying or irradiation drying.

[0013] As a further description of the above technical solution: In step S300, the stirring speed of the wet granulator is set to 200 r / min, the shearing speed is set to 1500 r / min, and the soft material preparation time is controlled to be 2 min.

[0014] As a further description of the above technical solution: In step S400, the inlet air temperature of the fluidized bed dryer is set to 60 °C.

[0015] As a further description of the above technical solution: In step S500, the mixing speed of the V-type mixer is set to 15 r / min, and the mixing time is set to 10 min.

[0016] In summary, due to the adoption of the above technical solution, the beneficial effects of the present invention are as follows: In the present invention, the compound tablet candy is composed of eight natural Chinese herbal medicines, namely Pueraria lobata, Hovenia dulcis, Morus alba, Citrus reticulata Blanco, Poria cocos, Zingiber officinale, Dendrobium officinale and Polygonatum sibiricum, and is compounded with maltodextrin, mint extract and vitamin C. First, the synergistic effects between Chinese herbal medicines are fully utilized. Pueraria lobata can promote ethanol metabolism, and Hovenia dulcis can inhibit alcohol absorption. The combination of the two significantly improves the anti-alcoholism efficiency; Morus alba and Citrus reticulata Blanco can protect the gastric mucosa and neutralize gastric acid, relieving nausea after drinking; Poria cocos and Zingiber officinale strengthen the spleen and regulate the middle energizer, reducing the burden on the gastrointestinal tract; Dendrobium officinale and Polygonatum sibiricum nourish yin and promote fluid production, relieving dry mouth and headache; through the multi-target synergistic effect of "anti-alcoholism - protecting the stomach - strengthening the spleen - nourishing yin" among various raw materials, the discomfort after drinking is comprehensively improved. Secondly, the added maltodextrin, mint extract and vitamin C can improve the hygroscopicity and fluidity of the raw material powder, neutralize the bitter taste of traditional Chinese medicine, and have a sour, sweet, cold and refreshing taste of fruits when eaten, effectively improving the eating experience of the compound tablet candy of Chinese herbal medicines. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a process flow block diagram of a preparation method of a compound tablet candy with anti-alcoholism function proposed by the present invention; Figure 2 It is a sample control diagram of four experimental groups in the zebrafish anti-alcoholism detection project - behavioral detection; Figure 3 It is a column chart of the experimental results of the zebrafish anti-alcoholism detection project - behavioral detection. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0018] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0019] Please refer to Figures 1 - 3 , the present invention provides a technical solution: a compound tablet candy with an anti-alcohol function, including the following components: 30-40 parts of kudzu root, 20-30 parts of oriental raisin tree seed, 8-16 parts of mulberry, 5-15 parts of dried tangerine peel, 5-15 parts of poria cocos, 2-6 parts of ginger, 2-6 parts of dendrobium officinale, 1-5 parts of polygonatum sibiricum, 15-25 parts of maltodextrin, and 1-3 parts of taste improver. Among them, the taste improver is a mixture of mint extract and vitamin C in a mass ratio of 2:1.

[0020] Specifically, as Figure 1 shown, a preparation method of a compound tablet candy with an anti-alcohol function includes the following steps: S100, raw material cleaning: Weigh kudzu root, oriental raisin tree seed, mulberry, dried tangerine peel, poria cocos, ginger, dendrobium officinale, and polygonatum sibiricum according to the above formula composition requirements, and clean them respectively through an ultrasonic cleaner for three minutes, and then drain the water and perform drying treatment for later use. Among them, the dried medicinal materials after cleaning can be dried by sun drying method, air drying method or irradiation drying method; S200, mixing and pulverizing: Pour the cleaned and dried medicinal materials in the previous step into a medicinal material pulverizer, pulverize continuously twice, and control the pulverizing time for each time to be 5-15 minutes. Then, screen the mixed powder through an 80-mesh sieve to obtain a mixed medicinal powder; S300, granulation processing: Mix the mixed medicinal powder prepared in the previous step with the taste improver according to the formula component requirements, and then centrally add it to a wet granulator, and use an ethanol solution with a volume fraction of 60% as a wetting agent for granulation treatment. Set the stirring speed of the wet granulator to 200r / min, the shearing speed to 1500r / min, and control the soft material making time to be 2min. The granules after granulation are then screened through a 20-mesh sieve to obtain wet mixed granules; S400, drying and sizing: Add the mixed granules prepared in the previous step to a fluidized bed dryer for drying treatment, set the inlet air temperature of the fluidized bed dryer to 60°C, and when the moisture content of the mixed granules ≤ 3%, screen them through a 16-mesh sieve to obtain dry mixed granules; S500, Tablet Pressing Process: The dry mixed granules obtained after drying and granulating are mixed with maltodextrin according to the requirements of the formula components, and then centrally added to a V-type mixer for mixing. The mixing speed of the V-type mixer is set at 15 r / min, and the mixing time is set at 10 min. The mixed mixture is added to a tablet press for tablet pressing, and the tablet weight is controlled at 0.5 g / tablet, finally obtaining compound tablet candies; S600, Packaging: According to the actual processing requirements, the compound tablet candies are packaged and sealed by means of bottling, bagging or blister pressing.

[0021] Example 1 30 parts of kudzu root, 20 parts of oriental raisin tree seed, 8 parts of mulberry, 5 parts of dried tangerine peel, 5 parts of poria cocos, 2 parts of ginger, 2 parts of dendrobium, 1 part of polygonatum sibiricum, 15 parts of maltodextrin, two-thirds part of peppermint extract and one-third part of vitamin C are used to prepare compound tablet candies according to the above preparation method, and the tablet weight is controlled at 0.5 g / tablet.

[0022] Verification of Hangover Effect Thirty healthy male volunteers aged 20 - 40 (without a history of alcohol allergy) are selected and randomly divided into an experimental group (taking the tablet candies of this example, 2 tablets are taken 30 min before drinking) and a control group (taking a placebo), with 15 people in each group. The subjects all drink 100 mL of 52-degree white liquor (containing about 42 g of ethanol), and the symptom scores within 2 h after drinking are recorded. Among them, the scoring range is 0 - 10 points, and the higher the score, the more obvious the discomfort. Then, the score values of the experimental group and the control group are statistically analyzed, and the specific results are shown in the following table:

[0023] The data show that the symptoms such as headache, nausea, and dry mouth after drinking in the experimental group are significantly lighter than those in the control group (p < 0.05), verifying the hangover effect of the tablet candies of the present invention.

[0024] Example 2 35 parts of kudzu root, 25 parts of oriental raisin tree seed, 12 parts of mulberry, 10 parts of dried tangerine peel, 10 parts of poria cocos, 4 parts of ginger, 4 parts of dendrobium, 3 parts of polygonatum sibiricum, 20 parts of maltodextrin, four-thirds part of peppermint extract and two-thirds part of vitamin C are used to prepare compound tablet candies according to the above preparation method, and the tablet weight is controlled at 0.5 g / tablet.

[0025] Verification of Hangover Effect Thirty healthy male volunteers aged 20 - 40 (without a history of alcohol allergy) were selected and randomly divided into an experimental group (taking the chewable candies of this embodiment, 2 tablets were taken 30 minutes before drinking) and a control group (taking a placebo), with 15 people in each group. All the subjects drank 100 mL of 52-degree Baijiu (containing approximately 42 g of ethanol), and the symptom scores within 2 hours after drinking were recorded. Among them, the scoring range was 0 - 10 points, and the higher the score, the more obvious the discomfort. Then, the score values of the experimental group and the control group were statistically analyzed, and the specific results are shown in the following table:

[0026] The data showed that the symptoms such as headache, nausea, and dry mouth in the experimental group after drinking were significantly lighter than those in the control group (p < 0.05), verifying the hangover effect of the chewable candies of the present invention.

[0027] Example 3 Forty parts of Pueraria lobata, thirty parts of Hovenia dulcis, sixteen parts of Morus alba, fifteen parts of Citrus reticulata Blanco, fifteen parts of Poria cocos, six parts of Zingiber officinale, six parts of Dendrobium officinale, five parts of Polygonatum sibiricum, twenty-five parts of maltodextrin, two parts of mint extract, and one part of vitamin C were used to prepare the compound chewable candies according to the above preparation method, and the tablet weight was controlled to be 0.5 g / tablet.

[0028] Verification of hangover effect Thirty healthy male volunteers aged 20 - 40 (without a history of alcohol allergy) were selected and randomly divided into an experimental group (taking the chewable candies of this embodiment, 2 tablets were taken 30 minutes before drinking) and a control group (taking a placebo), with 15 people in each group. All the subjects drank 100 mL of 52-degree Baijiu (containing approximately 42 g of ethanol), and the symptom scores within 2 hours after drinking were recorded. Among them, the scoring range was 0 - 10 points, and the higher the score, the more obvious the discomfort. Then, the score values of the experimental group and the control group were statistically analyzed, and the specific results are shown in the following table:

[0029] The data showed that the symptoms such as headache, nausea, and dry mouth in the experimental group after drinking were significantly lighter than those in the control group (p < 0.05), verifying the hangover effect of the chewable candies of the present invention.

[0030] In summary, the hangover-relief effects of Examples 1, 2, and 3 demonstrate that the composite compressed candies produced using the above-described formulations and preparation methods are capable of alleviating symptoms such as headache, nausea, and dry mouth in drinkers after drinking, demonstrating hangover-relief efficacy. Furthermore, while the amounts of each component added in Examples 1, 2, and 3 were gradually increased, the scoring data revealed that the difference in scores between the experimental groups after consuming the composite compressed candies in Examples 2 and 3 was not significant. Based on manufacturing cost, efficacy, and experimental data, Example 2 is the optimal embodiment of the present invention, and the composite compressed candies produced using Example 2 offer greater cost-effectiveness and stability.

[0031] To further verify whether the prepared composite compressed candy has the effect of sobering up, the composite compressed candy prepared in Example 2 was submitted for testing. Feifan Standard Technical Services (Suzhou) Co., Ltd. was commissioned to conduct a zebrafish sobering up test project - behavioral testing on the sample of Pueraria root, Hovenia dulcis, Huoshan dendrobium, mulberry, tangerine peel, and Poria cocos compressed candy. The analysis and test report number is FFC202500207. The official website of the commissioning company is: www.feifaantest.com. The sobering up test efficacy was verified using a laboratory test method. The specific content is as follows: 1. Brief description of laboratory methods 1. Detection Principle: Drunkenness is actually acute ethanol intoxication, which excites the brain and causes abnormal behavior. After entering the body, 90% of ethanol enters the liver for metabolism. Alcohol dehydrogenase (ADH) oxidizes it to acetaldehyde. Under the catalysis of acetaldehyde dehydrogenase (ALDH), acetaldehyde is converted into acetic acid and finally into carbon dioxide and water. The action of ADH and ALDH enzymes allows ethanol to be metabolized by the body without causing damage. Because zebrafish have a similar digestive system to humans, including a liver and intestines, their digestion, nutrient absorption, and transport processes are highly similar to humans. When excessive ethanol is ingested, it is metabolized to produce large amounts of acetaldehyde, which accumulates in the body and causes symptoms of drunkenness. The effectiveness of the sample in detoxifying alcohol is evaluated by measuring total movement distance. Using a behavioral analyzer to analyze the movement trajectories of zebrafish, the total movement distance of intoxicated zebrafish was significantly reduced compared to normal zebrafish.

[0032] The positive control drug in this experiment was RU21. RU21 promotes the secretion of dehydrogenase, an enzyme that accelerates the breakdown of acetaldehyde, a harmful substance in alcohol metabolism. By increasing dehydrogenase activity, RU21 accelerates the breakdown of acetaldehyde, rapidly converting it into harmless substances that can be excreted from the body, thereby reducing the harmful effects of acetaldehyde on the body.

[0033] 2. Materials and Methods 2.1 Experimental instruments and reagents Zebrafish Behavior Trajectory Tracking System (DanioVision) (BOM-ZDAN-OBS, NorData (Beijing) Information Technology Co., Ltd.), absolute ethanol (CAS: 64-17-5), RU21 (imported from the United States) 2.2 Detection System and Sample Size Experimental System: Wild AB strain zebrafish Zebrafish Age: 3 days after fertilization Sample Size per Group of Experiments: 12 fish per well, 1 well per group Adult Fish Rearing and Reproduction Method: According to the company's standard rearing and reproduction method 3. Experimental Procedure We divided the zebrafish to be tested into four groups, namely the normal control group, the model control group, the positive control group, and the sample treatment group. Among them, the normal control group was not treated with anything. The model control group, the sample treatment group, and the positive control group all ingested an equal amount of ethanol (ethanol was ingested into the zebrafish by dissolving it in the fish-raising water). The positive control group ingested ethanol and RU21 at the same time, and the sample treatment group ingested ethanol and the sample at the same time. After a period of time, we conducted behavioral analysis on the zebrafish, and finally presented the total movement distance of the zebrafish as the result.

[0034] II. Applicability and Limitations Used for the detection of hangover projects of health products and their raw materials. It is required that the sample can be dissolved in water or prepared into a uniformly dispersed suspension in water.

[0035] III. Data Processing Method SPSS 26 software was used for analysis, GraphPad Prism 8 was used for graphing, and the experimental results were statistically expressed as mean ± standard deviation. The SPSS software was used for normal distribution test. If the data conformed to the normal distribution, the data significance was tested using the T parameter test or analysis of variance (ANOVA). If the data did not conform to the normal distribution, non-parametric test was used (a result P value < 0.05 indicates a statistically significant difference).

[0036] IV. Judgment Basis On the basis that the experiment meets the effectiveness, compared with the blank control group, the significant reduction in the total movement distance of the model control group (P < 0.05) means that the modeling is successful.

[0037] Compared with the model control group, the significant increase in the total movement distance of the sample treatment group (P < 0.05) indicates that the sample has a hangover effect.

[0038] V. Preliminary Experiment Detection Results There was no significant difference between the 1000 mg / L sample group and the blank control group. Therefore, 1000 mg / L is the maximum safe concentration.

[0039] VI. Detection Results

[0040] Appended Table of Results:

[0041] Specifically, as Figure 2 and Figure 3 shown, it is the sample control diagram and the column chart of the efficacy test results of four experimental groups in the zebrafish anti-hangover detection project - behavioral detection. Figure 3 Among them, *: P < 0.05, **: P < 0.01, ***: P < 0.001. Among them, the more *, the smaller P represents the more obvious the difference. By analyzing Figure 2 and Figure 3 it is verified that the compounded compressed candies of the present invention have the anti-hangover efficacy.

[0042] The above is only the preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present invention, according to the technical solution and inventive concept of the present invention, makes equivalent substitutions or changes, and all should be covered within the protection scope of the present invention.

Claims

1. A compound tablet candy with a function of relieving hangover, characterized in that, It includes the following components: 30-40 parts of kudzu root, 20-30 parts of oriental raisin tree fruit, 8-16 parts of mulberry, 5-15 parts of dried tangerine peel, 5-15 parts of poria cocos, 2-6 parts of ginger, 2-6 parts of dendrobium officinale, 1-5 parts of polygonatum sibiricum, 15-25 parts of maltodextrin, and 1-3 parts of taste improver.

2. The compound tablet candy with hangover function according to claim 1, characterized in that, The said kudzu root is 30 parts, oriental raisin tree fruit is 20 parts, mulberry is 8 parts, dried tangerine peel is 5 parts, poria cocos is 5 parts, ginger is 2 parts, dendrobium officinale is 2 parts, polygonatum sibiricum is 1 part, maltodextrin is 15 parts, and taste improver is 1 part.

3. A compound tablet candy with an alcohol-relieving function according to claim 1, characterized in that, The said kudzu root is 35 parts, oriental raisin tree fruit is 25 parts, mulberry is 12 parts, dried tangerine peel is 10 parts, poria cocos is 10 parts, ginger is 4 parts, dendrobium officinale is 4 parts, polygonatum sibiricum is 3 parts, maltodextrin is 20 parts, and taste improver is 2 parts.

4. A compound tablet candy with an alcohol-relieving function according to claim 1, characterized in that, The said kudzu root is 40 parts, oriental raisin tree fruit is 30 parts, mulberry is 16 parts, dried tangerine peel is 15 parts, poria cocos is 15 parts, ginger is 6 parts, dendrobium officinale is 6 parts, polygonatum sibiricum is 5 parts, maltodextrin is 25 parts, and taste improver is 3 parts.

5. A compound tablet candy with a hangover-relieving function according to claim 1, characterized in that, The said taste improver is a mixture of mint extract and vitamin C in a mass ratio of 2:

1.

6. The preparation method of a compound tablet candy with hangover function according to claim 1, characterized in that, The said method includes the following steps: S100, Raw material cleaning: Weigh kudzu root, oriental raisin tree fruit, mulberry, dried tangerine peel, poria cocos, ginger, dendrobium officinale, and polygonatum sibiricum according to the above formula composition requirements, clean them in an ultrasonic cleaner for three minutes respectively, then drain the water and carry out drying treatment for later use; S200, Mixing and pulverizing: Pour the cleaned and dried medicinal materials in the previous step into a medicinal material pulverizer, pulverize continuously twice, control the pulverizing time for each time to be 5-15 minutes, and then screen the mixed powder through an 80-mesh sieve to obtain mixed medicinal powder; S300, Granulation processing: Mix the mixed medicinal powder obtained in the previous step with the taste improver according to the formula component requirements, then centrally add it to a wet granulator, use an ethanol solution with a volume fraction of 60% as a wetting agent for granulation treatment, and then screen the granulated particles through a 20-mesh sieve to obtain wet mixed particles; S400, Drying and sizing: Add the mixed particles obtained in the previous step to a fluidized bed dryer for drying treatment. When the moisture content of the mixed particles is ≤3%, it can be screened through a 16-mesh sieve to obtain dry mixed particles; S500, Tabletting processing: Mix the dry mixed particles obtained after drying and sizing with maltodextrin according to the formula component requirements, then centrally add it to a V-type mixer for mixing treatment, and add the mixed mixture to a tabletting machine for tabletting treatment, control the tablet weight to be 0.5 g / tablet, and finally obtain compound tablet candies; S600, Packaging: According to the actual processing requirements, carry out packaging and sealing treatment on the compound tablet candies by means of bottling, bagging or blister pressing plate packaging.

7. The preparation method of a compound tablet candy with hangover function according to claim 6, characterized in that, In the said step S100, the cleaned medicinal materials can be dried by means of sun drying, air drying or irradiation drying.

8. The preparation method of a compound tablet candy with hangover function according to claim 6, characterized in that, In the said step S300, the stirring speed of the wet granulator is set to 200 r / min, the shearing speed is set to 1500 r / min, and the soft material making time is controlled to be 2 min.

9. The preparation method of a compounded chewable candy with hangover function according to claim 6, characterized in that, In the said step S400, the inlet air temperature of the fluidized bed dryer is set to 60 °C.

10. The preparation method of a compound tablet candy with hangover function according to claim 6, characterized in that, In the step S500, the mixing speed of the V-type mixer is set to 15 r / min, and the mixing time is set to 10 min.

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