Traditional Chinese medicine compatibility prescription and application thereof

Abstract

The invention provides a traditional Chinese medicine compatibility prescription and application thereof. A four-type medicine classification system of'master, slave, ingredient and sum 'is adopted, the proportion of the master medicine is 50%, the proportion of the slave medicine is 25%, the proportion of the auxiliary medicine is 15%, the proportion of the sum medicine is 10%, the master medicine is a medicine aiming at core pathogenesis, the slave medicine is a medicine for assisting the master medicine or relieving side effects of the auxiliary medicine, the auxiliary medicine is a medicine for indirectly supporting the functions of the master medicine and the slave medicine, and the sum medicine is a medicine for coordinating the properties of the whole prescription. According to the traditional Chinese medicine compatibility prescription of'master, slave, compounding and mixing 'provided by the invention, the leading effect of the core medicine is highlighted and the synergistic effect of the auxiliary medicine can be considered by determining the function positioning and proportion of the master medicine, the slave medicine, the compounding medicine and the mixing medicine, so that the overall curative effect of the prescription is improved. A dynamic adjustment mechanism is emphasized, the medicine proportion and combination can be flexibly adjusted according to different stages of diseases and individual differences of patients, complex and changeable clinical requirements are effectively met, and the defect that roles are solidified in a traditional theory is overcome.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine, and in particular to a Chinese medicine compatibility prescription and its application, a Chinese medicine formula based on four types of drug relationships, namely, "main, subordinate, matching and harmony", and its clinical application. Background Art

[0002] The traditional Chinese medicine compatibility theory is centered on the "monarch, minister, assistant and envoy" theory, and its classification criteria are based on the tonic and purgative properties, toxicity and hierarchy of the drugs. It has limitations such as theoretical rigidity, lack of flexibility and difficulty in understanding. In traditional theory, the roles of monarch, minister, assistant and envoy are rigid and cannot adapt to the complex and changing needs of clinical diseases and syndromes; the same drug needs to adjust its role in different diseases, but the traditional theory does not clearly define the dynamic adjustment mechanism; in addition, the metaphor of monarch, minister, assistant and envoy has a feudal hierarchical color, which is out of touch with modern medical thinking and is not conducive to academic promotion. In the existing literature, the monarch, minister, assistant and envoy theory has not been systematically deepened and verified in clinical practice, resulting in its limited guiding role in modern Chinese medicine prescription composition. The present invention aims to innovate the theory of Chinese medicine compatibility and propose four types of drug relationships: "dominant, subordinate, pairing and harmony" to solve the above problems. Summary of the Invention

[0003] In view of this, in order to solve the problems existing in the technical background, the present invention proposes a Chinese medicine compatibility prescription and application thereof.

[0004] A Chinese medicine combination prescription is characterized by adopting a four-category drug classification system of "main, auxiliary, coordinating, and harmonizing", wherein the main drug accounts for 50%, the auxiliary drug accounts for 25%, the coordinating drug accounts for 15%, and the harmonizing drug accounts for 10%.

[0005] Furthermore, the main drug is a drug targeting the core pathogenesis, the auxiliary drug is a drug that assists the main drug or alleviates its side effects, the adjuvant is a drug that indirectly supports the functions of the main and auxiliary drugs, and the reconciliation drug is a drug that coordinates the medicinal properties of the entire prescription.

[0006] Furthermore, the proportions and combinations of the four types of drugs are dynamically adjusted according to the stage of the patient's disease course.

[0007] An application of the above-mentioned Chinese medicine combination prescription includes the preparation of Chinese medicine compound preparations for treating deficiency and excess, cold and heat, yin and yang, exterior and interior syndromes, and dynamically adjusting the proportions and combinations of the four types of drugs: main, auxiliary, coordinating, and harmonizing, to adapt to different stages of the disease course and individualized needs of patients, thereby achieving flexible prescription, intuitive compatibility, and scientific use of drugs, thereby improving clinical efficacy and safety.

[0008] The above technical solution has the following beneficial effects:

[0009] The invention proposes a "main, secondary, complementary and harmonious" Chinese medicine compatibility prescription, which highlights the leading role of the core medicine by clarifying the functional positioning and proportion (50%, 25%, 15%, 10%) of the main medicine, secondary medicine, complementary medicine and harmonious medicine, while taking into account the synergistic effect of auxiliary medicines, thereby improving the overall efficacy of the prescription. The present invention emphasizes a dynamic adjustment mechanism, which can flexibly adjust the proportion and combination of drugs according to the different stages of the disease and the individual differences of patients, effectively respond to complex and changeable clinical needs, and avoid the drawbacks of role solidification in traditional theories. The present invention focuses on the functional orientation and synergistic relationship between drugs, conforms to the concept of evidence-based medicine, can optimize the prescription structure, reduce the antagonistic effect between drugs, enhance the safety and effectiveness of treatment, and provides a scientific, flexible and efficient guidance scheme for the compatibility of Chinese medicine. DETAILED DESCRIPTION

[0010] The following is a clear and complete description of the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making any creative efforts are within the scope of protection of the present invention.

[0011] A prescription for Chinese medicine combination includes a four-category drug classification system of "main, auxiliary, coordinating, and harmonizing", wherein the main drug accounts for 50%, the auxiliary drug accounts for 25%, the coordinating drug accounts for 15%, and the harmonizing drug accounts for 10%. The main drug is a drug targeting the core pathogenesis, the auxiliary drug is a drug that assists the main drug or alleviates its side effects, the coordinating drug is a drug that indirectly supports the functions of the main and auxiliary drugs, and the harmonizing drug is a drug that coordinates the medicinal properties of the entire prescription. The proportions and combinations of the four types of drugs are dynamically adjusted according to the patient's disease stage.

[0012] An application of the above-mentioned Chinese medicine combination prescription includes the preparation of Chinese medicine compound preparations for treating deficiency and excess, cold and heat, yin and yang, exterior and interior syndromes, and dynamically adjusting the proportions and combinations of the four types of drugs: main, auxiliary, coordinating, and harmonizing, to adapt to different stages of the disease course and individualized needs of patients, thereby achieving flexible prescription, intuitive compatibility, and scientific use of drugs, thereby improving clinical efficacy and safety.

[0013] During specific use, the core pathogenesis is determined based on the patient's symptoms (deficiency or excess, cold or heat, yin or yang, exterior or interior), and the principal drug is selected. Formulas are formulated with a ratio of 50% principal drug, 25% secondary drug, 15% supplementary drug, and 10% harmonizing drug. This ensures a clear division of labor among the drugs and forms an efficient treatment team. Dynamic Adjustment: Adjust the ratio of principal, secondary, and harmonizing drugs as the disease progresses. For example, when the pathogenic factors have been eliminated and the righteousness is at peace, the primary focus may be on nurturing while also providing some treatment.

[0014] This method emphasizes the synergistic effect between drugs, maximizes the therapeutic effect of traditional Chinese medicine through reasonable compatibility and dynamic adjustment, and reduces side effects, providing a scientific, flexible and efficient prescription strategy for clinical practice.

[0015] In the present embodiment, the core pathogenesis is determined according to the patient's symptoms (deficiency and excess cold and heat, yin and yang exterior and interior), and the main medicine is selected. The main medicine accounts for 50%, such as grains are staple foods and vegetables are side dishes; the secondary medicine accounts for 25%, and vegetables and fruits other than grains are supplementary foods; the auxiliary medicine accounts for 15%, such as firewood, fire, pot, stove, and spatula, which should be compatible with the staple food; and the auxiliary medicine accounts for 10%. Chinese medicine formulas such as cooking and frying, through the careful preparation of the main and secondary ingredients and the cooking of the supporting (pot, stove, firewood) equipment, a pot of fragrant meals is formed. Although a good decoction is not necessarily suitable for the mouth, it is suitable for the stomach, is beneficial to the patient, and is not damaged in the vital energy, so that the evil is removed and the body is safe, and it is a master. For example, how much oil, salt, sauce, vinegar, etc. are used according to how many dishes are served, can maximize the help of digestion and absorption, and as the course of the disease progresses, the main and secondary proportions are adjusted. Because Chinese medicine emphasizes the unity of man and nature, its core concept is that man is closely related to the natural environment between heaven and earth. Man was originally formed by responding to the qi of heaven and earth and gradually evolving. The same principle applies to the compatibility and application of Chinese medicine: if the compatibility is appropriate, success will be achieved; if the compatibility is inappropriate, nothing will be achieved. Chinese medicines gradually grow by responding to the wind, rain and sunshine of nature. Because of their different characteristics and disparate natures, they vary greatly. When used to treat diseases, a single Chinese medicine has both good adaptability and shortcomings. The purpose of Chinese medicine compatibility is to promote its strengths and suppress its weaknesses. Promoting its strengths means increasing its dosage and highlighting its individuality, so as to better play its leading role.

[0016] Traditional Chinese Medicine (TCM), a discipline steeped in philosophical thought, seeks to uncover the dynamic patterns of treatment and prescription composition. To prioritize the importance of prescriptions and medications, as well as the organizational structure and order between medications, better leverage the breakthrough capabilities of the prescription-drug team, and actively guide prescription compatibility, innovation is essential, forging new paths. This requires perfecting, enriching, refining, and digesting the essence of the theory of monarch, minister, assistant, and envoy, allowing for truly flexible and agile application. This will make clinical prescriptions more valuable, more practical, and more accessible to the public, rather than superficial, superficial, or superficial. The term monarch, minister, assistant, and envoy can be updated to encompass four characters: principal, following, matching, and harmonizing. These four characters are relatively easy to understand, highly concise, and convey a precise meaning, offering significant clinical guidance. The present invention proposes an innovative prescription method for Chinese medicine compatibility, replacing the traditional monarch, minister, assistant and envoy theory with the four relationships of "primary, secondary, auxiliary and harmonious", breaking through its limitations, specifically including: classification definition: principal medicine (accounting for 50%) is the medicine that targets the core pathogenesis and plays a leading therapeutic role; secondary medicine (accounting for 25%) assists the principal medicine to enhance the efficacy or alleviate its side effects; auxiliary medicine (accounting for 15%) supports the principal and secondary medicine through indirect effects; and harmonious medicine (accounting for 10%) coordinates the relationship between the medicines in the whole prescription to ensure the balance of medicinal properties and synergistic effect. Now, monarch can be replaced by principal, minister by secondary, auxiliary by auxiliary and envoy by harmonious. In this way, we can understand the compatibility principle of monarch, minister, assistant and envoy more comprehensively, deeply and directly, grasp its essence, and use its skills reasonably and skillfully. Using medicine is like using soldiers, and knowing medicine is like knowing people. You can know its nature before you know its use. The establishment of the theory of TCM compatibility, which includes principal (50%), subordinate (25%), auxiliary (15%), and guiding (10%), has deepened the understanding of the monarch, minister, assistant, and envoy principles from another perspective, developing this theory and opening up a new avenue for the application of TCM compatibility. Dynamic adjustment: The proportions and combinations of the four medicinal categories are dynamically adjusted based on the stage of the disease (e.g., early, middle, or late stages) and individual patient differences. Many diseases exhibit characteristics of deficiency, excess, cold, heat, and both yin and yang, exterior and interior. Deficiency syndromes are divided into yin and yang, exterior and interior; excess syndromes also have yin and yang, exterior and interior; cold syndromes also have yin and yang, exterior and interior; and heat syndromes also have yin and yang, exterior and interior. The application of TCM compatibility must be combined with identification and differentiation of symptoms. Identifying the medicine without understanding the symptoms is like having a missile without a guidance system; it will not be able to achieve its intended effect. Therefore, TCM compatibility is not a simple accumulation of drugs; it has a guiding principle: first identify the symptoms, then identify and diagnose them. Diagnosis is the process of debate and identification, and diagnosis is the diagnosis derived through differentiation. Therefore, the purpose of syndrome differentiation and diagnosis is to guide and organize the thinking for drug selection and formulation. To understand drug compatibility, one must first grasp the core concept of syndrome differentiation and treatment. Syndrome is the summary, induction, definition, and determination of symptoms. Syndrome is a high-level summary of symptoms, a systematic organization and arrangement of scattered and chaotic symptoms. This arrangement has a hierarchy of priority, sequence, importance, and primary and secondary, and it provides direction for drug selection and formulation (monarch, minister, assistant, and envoy).The purpose of matching and positioning the relationships between master, slave, cooperator and harmony is to make the division of labor among drugs clear and the division of responsibilities orderly, so that it is complicated but not messy, and numerous but not chaotic, thus forming an organized, well-planned and combat-ready team.

[0017] The above describes the basic principles and main features of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The above embodiments and descriptions only illustrate the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the invention to be protected. The scope of protection of the invention is defined by the attached claims and their equivalents.

Claims

1. A Chinese medicine compatibility prescription, characterized in that: A four-category drug classification system of "main, auxiliary, matching, and harmony" is adopted, among which main drugs account for 50%, auxiliary drugs account for 25%, matching drugs account for 15%, and harmony drugs account for 10%.

2. A Chinese medicine compatibility prescription according to claim 1, characterized in that: The main drug is a drug targeting the core pathogenesis, the auxiliary drug is a drug that assists the main drug or alleviates its side effects, the adjuvant is a drug that indirectly supports the functions of the main and auxiliary drugs, and the reconciliation drug is a drug that coordinates the medicinal properties of the entire prescription.

3. A Chinese medicine compatibility prescription according to claim 1, characterized in that: The proportions and combinations of the four types of drugs are dynamically adjusted according to the stage of the patient's disease course.

4. An application of the above-mentioned Chinese medicine compatibility prescription, characterized in that, It includes traditional Chinese medicine compound preparations used to treat deficiency and excess, cold and heat, yin and yang, exterior and interior syndromes. By dynamically adjusting the proportions and combinations of the four types of drugs: main, auxiliary, supporting, and harmonizing, it adapts to different stages of the disease and individualized needs of patients, achieves flexible prescription, intuitive compatibility and scientific use of drugs, and improves clinical efficacy and safety.