View field deflectable microscope objective

Abstract

The invention provides a field-of-view deflectable microscope objective. The microscope objective is composed of a liquid I, a liquid II, a liquid-liquid shaping sheet, a driving electrode of the liquid-liquid shaping sheet, a solid lens, a self-adaptive lens, a lens barrel, a self-adaptive lens driver and a liquid-liquid level deflection driver. Under an initial condition, the liquid-liquid shaping sheet is kept horizontal, and the adaptive lens controller applies driving information to change the curvature radius on the adaptive lens, so that a sample is clearly imaged. When a larger view field range needs to be observed, the liquid-liquid level deflection driver is used for conducting regional power-up on the liquid-liquid level, so that the liquid-liquid level deflects. Meanwhile, the two-dimensional deflection of the microscopic view field is realized by changing the signal correction aberration applied to the adaptive lens. According to the microscope objective, the size of the field of view of microscopic observation is obviously improved on the premise of not losing the resolution, and meanwhile, the microscope objective has the advantages of no mechanical movement, light weight, integration and easiness in control.

Description

Technical Field

[0001] The present invention relates to a microscope objective lens, and more particularly to a microscope objective lens with a deflectable field of view. Background Art

[0002] Microscopes play a vital role in scientific research, production, and everyday life, including medical testing, life sciences, and microstructure processing. Conventional microscopic imaging observations often struggle to balance high resolution with a wide field of view. Achieving this trinity of wide field of view, high resolution, and real-time performance in microscopy presents significant challenges. Conventional optical microscopes, through discrete zoom, enable observation at varying magnifications, which can alleviate this trade-off to some extent. However, with the advancement of scientific research, fields such as life sciences are placing higher demands on microscopic observation performance. In recent years, wide-field microscopy, which utilizes deflection device scanning and multi-sensor parallel acquisition, has effectively increased the field of view. However, these technologies present several challenges: Conventional beam deflection devices are large, difficult to control, and difficult to integrate, making them incompatible with the highly integrated requirements of modern instrumentation. Multi-lens systems for parallel acquisition are often bulky and costly, necessitating the urgent need for lightweight, integrated optical deflection devices to increase the field of view. Furthermore, the deflection process of optical deflection devices inevitably introduces certain aberrations. Mechanically adjusting these aberrations is slow and can cause image quality degradation and jitter, severely impacting imaging efficiency. Therefore, there is still a lack of large-field microscope objectives with high integration, lightweight, easy control, and high-resolution performance. Summary of the Invention

[0003] The present invention proposes a microscope objective lens with a deflectable field of view. Figure 1 As shown, the microscope objective lens includes liquid I, liquid II, a liquid-liquid shaping plate, a driving electrode of the liquid-liquid shaping plate, a solid lens, an adaptive lens, a lens barrel, an adaptive lens driver and a liquid-liquid surface deflection driver.

[0004] As attached Figure 1 As shown in the figure, under the initial conditions, the liquid-liquid shaping sheet remains horizontal, the optical path is not deflected, and the adaptive lens controller applies driving information to the adaptive lens inside the field-of-view deflectable microscope objective lens, changing the curvature radius to make the sample clearly imaged. Figure 2 As shown in FIG, when a larger field of view needs to be observed, the rear working distance is kept unchanged, and the liquid-liquid surface of the field-deflectable microscope objective lens is energized in different regions using a liquid-liquid surface deflection driver, as shown in FIG. Figure 3As shown, the liquid-liquid surface is deflected, and the liquid surface deflection angle is related to the power-on size and the liquid level height of liquid I and liquid II, thereby determining the microscopic field of view increase rate. At the same time, changing the signal applied to the adaptive lens inside the field of view deflectable microlens can change the curvature radius of the adaptive lens, and the correction of aberrations is achieved through a special design optimization value. Therefore, this microlens achieves two-dimensional dynamic deflection of the microscopic field of view while ensuring resolution. Because this microlens utilizes a liquid-liquid shaping sheet to achieve field of view deflection and utilizes an adaptive lens to correct aberrations, the field of view size of microscopic observation is significantly improved without losing resolution, and has the advantages of no mechanical movement, lightweight, integration, and easy control. It should be pointed out that, unlike traditional microlens, in this microlens, the deflection of the liquid-liquid shaping sheet is the factor that realizes the field of view deflection of the microlens, and the change of the curvature radius of the adaptive lens is to correct aberrations, correcting the aberrations caused by the field of view deflection.

[0005] Preferably, liquid 1 and liquid 2 are mutually immiscible liquids.

[0006] Preferably, the shape of the liquid-liquid shaping sheet can be rectangular, oval, circular, etc.

[0007] Preferably, the material of the liquid-liquid shaping sheet can be a light-transmitting material such as plastic, glass, crystal, etc.

[0008] Preferably, the driving electrodes of the liquid-liquid shaping sheet can adopt a structure in the form of a quadrangular prism, a hexagonal prism, etc.

[0009] Preferably, the liquid-liquid shaping sheet can be driven by electrowetting or other methods.

[0010] Preferably, the field of view of the deflectable microscope objective lens has M adaptive lenses, where 2≤ M ≤8.

[0011] Preferably, the adaptive lens is a liquid lens, a polymer lens, a liquid crystal lens, etc. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 The figure is a schematic diagram of the initial structure of a microscope objective lens with a deflectable field of view according to the present invention.

[0013] Figure 2 The figure is a schematic diagram of liquid-liquid surface deflection of a microscope objective lens with a deflectable field of view according to the present invention.

[0014] Figure 3 This is a top view of the liquid-liquid shaping plate driving of a microscope objective lens with a deflectable field of view according to the present invention.

[0015] Figure 4 This is a point diagram before deflection in an embodiment of a microscope objective lens with a deflectable field of view according to the present invention.

[0016] Figure 5 This is a point diagram after deflection in an embodiment of a microscope objective lens with a deflectable field of view according to the present invention.

[0017] Figure 6 This is a point diagram after deflection correction in an embodiment of a microscope objective lens with a deflectable field of view according to the present invention.

[0018] The diagrams in the above drawings are numbered as follows: 1. Driving electrode of liquid-liquid shaping sheet, 2. Liquid I, 3. Liquid-liquid shaping sheet, 4. Liquid II, 5. Solid lens, 6. Adaptive lens, 7. Lens barrel, 8. Adaptive lens driver, 9. Liquid-liquid surface deflection driver, 10. Sample.

[0019] It should be understood that the above drawings are merely schematic and not drawn to scale. DETAILED DESCRIPTION

[0020] The following detailed description of an embodiment of a liquid photonic device-based microscopic objective lens with a deflectable field of view proposed by the present invention further illustrates the present invention. It should be noted that the following embodiments are intended only to further illustrate the present invention and are not to be construed as limiting the scope of protection of the present invention. Non-essential improvements and adjustments made by persons skilled in the art based on the above disclosure are still within the scope of protection of the present invention.

[0021] A field-of-view deflectable microscope objective lens in this embodiment includes a liquid I, a liquid II, a liquid-liquid shaping sheet, a driving electrode for the liquid-liquid shaping sheet, a solid lens, an adaptive lens, a lens barrel, an adaptive lens driver, and a liquid-liquid surface deflection driver. Specifically, it comprises one liquid-liquid shaping sheet, three adaptive lenses, and a solid lens. In this embodiment, the refractive index of liquid I is 1.38, and the refractive index of liquid II is 1.51. The liquid-liquid shaping sheet is circular and made of plastic, and is driven by electrowetting to achieve field-of-view deflection. The adaptive lens is driven by mechanical wetting to correct aberrations. The solid lens is used to increase optical power. The driving electrode for the liquid-liquid shaping sheet is a hexagonal prism. The lens barrel protects and integrates the lens. The liquid-liquid surface deflection driver is used to apply voltage to the liquid-liquid surface of the field-of-view deflectable microscope objective lens in different regions, causing the liquid-liquid surface to deflect. The adaptive lens controller is used to apply a driving voltage to the adaptive lens within the field-of-view deflectable microscope objective lens, changing the radius of curvature. The overall magnification of the microscope objective is 5×.

[0022] When the driving voltage of the liquid-liquid shaping piece is 0V, that is, the liquid-liquid surface does not deflect, and under the control of the adaptive lens controller, the curvature of the three adaptive lenses from top to bottom is 0.043mm -1 , 0.1mm-1 、-0.097mm -1 The initial field of view size is 12.4416mm×9.8304mm, and the point diagram is as shown in the attached figure. Figure 4 When the driving voltage of the liquid-liquid shaping sheet is 98V, that is, when the liquid-liquid surface has a maximum deflection angle of 20°, the point diagram is as shown in the attached figure. Figure 5 As shown, there is aberration introduced by deflection. Under the control of the adaptive lens controller, the curvature of the three adaptive lenses changes from top to bottom to 0.045mm. -1 , 0.1mm -1 、-0.1mm -1 When the horizontal field of view is offset by 3.879mm, the vertical field of view is offset by 2.853mm, and the field of view can be increased by up to 31.18% overall. The spot diagram is shown in the attached figure. Figure 6 This microscope objective uses a liquid-liquid shaping piece and an adaptive lens for combined adjustment, enabling large-field, high-resolution microscopic observation.

Claims

1. A microscope objective lens with a deflectable field of view, comprising a liquid I, a liquid II, a liquid-liquid shaping sheet, a driving electrode for the liquid-liquid shaping sheet, a solid lens, an adaptive lens, a lens barrel, an adaptive lens driver, and a liquid-liquid level deflection driver, characterized in that: The liquid-liquid surface deflection driver energizes the liquid-liquid surface of the field-of-view deflectable microscope objective lens in different regions to realize the field-of-view deflection function; the adaptive lens controller applies a driving voltage to the adaptive lens inside the field-of-view deflectable microscope objective lens to change the curvature radius and realize the aberration correction function after deflection.

2. A microscope objective lens with a deflectable field of view according to claim 1, characterized in that: Liquid I and Liquid II are immiscible liquids.

3. A microscope objective lens with a deflectable field of view according to claim 1, characterized in that: The shape of the liquid-liquid shaping sheet can be rectangular, oval, circular, etc.

4. A microscope objective lens with a deflectable field of view according to claim 1, characterized in that: The material of the liquid-liquid shaping sheet can be a light-transmitting material such as plastic, glass, crystal, etc.

5. The microscope objective lens with a deflectable field of view according to claim 1, wherein: The driving electrodes of the liquid-liquid shaping sheet can adopt a structure in the form of a quadrangular prism, a hexagonal prism, etc.

6. A microscope objective lens with a deflectable field of view according to claim 1, characterized in that: The liquid-liquid shaping sheet can be driven by electrowetting or other methods.

7. The microscope objective lens with a deflectable field of view according to claim 1, characterized in that: Field of view can be deflected in microscope objective lens M adaptive lenses, where 2≤ M ≤8.

8. The microscope objective lens with a deflectable field of view according to claim 1, wherein: Adaptive lenses include liquid lenses, polymer lenses, and liquid crystal lenses.

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