Electronic microarray chip detector

Abstract

The invention discloses an electronic microarray chip detector, and belongs to the technical field of biological detection, the electronic microarray chip detector comprises a bottom plate and a shell assembly arranged on the bottom plate, and a plurality of assemblies are integrated in the shell assembly. The reagent bin assembly can be used for storing a NaCl solution, an SSC buffer solution and an enzyme digestion reagent; the power socket assembly is arranged on the side wall of the shell assembly and used for connecting an external power supply. The sampling needle assembly comprises a sampling needle and a driving mechanism and can accurately draw a reagent. The chip bin assembly can contain a detection chip and move to a detection station, a rotary valve is arranged in the chip bin assembly, the sampling needle is connected with an inlet of the rotary valve through an independent pipeline, and an outlet of the rotary valve is connected with a confluence plate. The pump assembly is provided with a three-way electromagnetic valve and an injection pump, the injection pump generates negative pressure, and the three-way electromagnetic valve injects reagents according to a time sequence. The control panel assembly is electrically connected with the multiple assemblies, receives voltage signals of the chip bin assembly and uploads the voltage signals to the industrial personal computer for analysis. The detector has the advantages of accurate sampling, efficient detection and high integration level, and can improve the accuracy and efficiency of qualitative detection of nucleic acid.

Description

Technical Field

[0001] The invention belongs to the technical field of biological detection and relates to an electronic microarray chip detector. Background Art

[0002] In the field of biological testing, electronic microarray chip detectors are of great significance for critical tasks such as qualitative nucleic acid detection. However, existing electronic microarray chip detectors on the market have significant shortcomings. They are often bulky, occupying a large amount of space, making them inconvenient to use and store. Moreover, the components within the instrument are dispersed and lack high integration, resulting in poor coordination between different functional modules. This not only complicates the testing process but also seriously affects detection efficiency, making it difficult to meet the growing demand for efficient testing. Summary of the Invention

[0003] The purpose of the present invention is to provide an electronic microarray chip detector that can achieve precise sampling, efficient detection, high integration, and improve the accuracy and efficiency of nucleic acid qualitative detection.

[0004] The purpose of the present invention is achieved through the following technical solutions: An electronic microarray chip detector includes a base plate and a housing assembly disposed on the base plate, wherein the housing assembly includes the following components: Reagent compartment assembly, used to store NaCl solution, SSC buffer and enzyme digestion reagent; A power socket assembly is provided on a side wall of the housing assembly and is used to connect an external power source to power the detector; The sampling needle assembly includes a sampling needle and a drive mechanism; the sampling needle is used to draw reagents from the reagent chamber assembly, and the drive mechanism is connected to the sampling needle to control the movement position of the sampling needle; The chip bin assembly is used to place the test chip and move the chip to the test station; the test station is provided with a test probe, and the manifold on the chip bin assembly is pressed down to fit the chip and press the chip onto the test probe; the chip bin assembly is also provided with a rotary valve, each of the sampling needles is connected to an inlet of the rotary valve through an independent pipeline, and the outlet of the rotary valve is connected to the inlet of the manifold; A pump assembly includes a three-way solenoid valve and a syringe pump; the syringe pump is located below the detection station and generates negative pressure on the chip above it. The outlet of the manifold is connected to the three-way solenoid valve, which injects different reagents into the ISFET sensor reaction area inside the chip in a timed manner; The control board assembly is arranged in the shell assembly and is electrically connected to the power socket assembly, the driving mechanism of the sampling needle assembly, the pump assembly and the chip bin assembly; the control board assembly receives the voltage signal from the chip bin assembly and uploads the received voltage signal to the industrial computer, which performs data analysis.

[0005] As a further improvement of an embodiment of the present invention, the reagent chamber assembly includes a support base fixed on the bottom plate, a reagent tube rack is provided on the support base, and at least four reagent tubes are provided on the reagent tube rack.

[0006] As a further improvement of an embodiment of the present invention, a dust cover is provided on the support base, the reagent tube rack and the reagent tubes are located in the dust cover, and the dust cover is provided with small holes corresponding to the reagent tubes.

[0007] As a further improvement of an embodiment of the present invention, one side of the dust cover is provided with a switch door, and the housing assembly is provided with a reagent compartment door corresponding to the switch door.

[0008] As a further improvement of one embodiment of the present invention, a diaphragm pump is also provided in the pump assembly, one end of the diaphragm pump is connected to the cleaning liquid tank through a pipeline, and the cleaning liquid cleans the liquid pipeline and the inside of the chip after passing through the diaphragm pump, and is finally discharged through the waste liquid port.

[0009] As a further improvement of one embodiment of the present invention, the sampling needle assembly includes a sampling bracket, and a vertically distributed driving mechanism is provided on the sampling bracket. The driving mechanism is a screw module driven by a stepper motor, and the connecting block of the screw module is connected to the sampling needle support plate, and the sampling needle is provided on the sampling needle support plate.

[0010] As a further improvement of one embodiment of the present invention, the shell assembly includes an instrument bottom shell and an instrument casing, and the instrument casing is provided with a reagent compartment door, a waste liquid compartment door, a chip in and out compartment door and a touch panel, and the touch panel is electrically connected to the control panel assembly.

[0011] As a further improvement of one embodiment of the present invention, the chip bin assembly includes a chip bin bracket, a chip feed bin and a convergence plate, the chip bin bracket is provided with a detection data board, and the detection data board is provided with a detection probe; the chip feed bin is provided with a chamber for placing the chip, and the chip feed bin can be moved to the detection station under the drive of the first driving mechanism, at which time the chip placed in the chamber is facing the detection probe; the convergence plate can be pressed down to be close to the chip and press the chip onto the detection probe under the drive of the second driving mechanism.

[0012] The above technical solution has the following beneficial effects: the components are highly integrated, the sampling needle assembly and the reagent chamber assembly cooperate to achieve precise sampling, the chip chamber assembly cooperates with the pump assembly to inject different reagents into the ISFET sensor reaction area inside the chip, and the detection probe is used to achieve efficient detection, thereby improving the accuracy and efficiency of qualitative nucleic acid detection; the application of the diaphragm pump can draw the cleaning liquid from the cleaning liquid tank, and after pressurization, the liquid pipeline and the inside of the chip are thoroughly cleaned, effectively removing residual reagents and impurities, avoiding cross contamination, and ensuring the independence and accuracy of each test. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] To more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for the embodiments or the description of the prior art. Obviously, the drawings described below are merely exemplary, and those skilled in the art can, without inventive effort, derive other implementation drawings based on the provided drawings.

[0014] The structures, proportions, sizes, etc. illustrated in this specification are intended only to complement the contents disclosed herein and to facilitate understanding and reading by persons familiar with the art. They are not intended to limit the conditions under which the present invention may be implemented and therefore have no substantive technical significance. Any structural modifications, changes in proportions, or adjustments in sizes, without affecting the efficacy and objectives of the present invention, shall still fall within the scope of the technical contents disclosed herein.

[0015] Figure 1 This is a schematic diagram of the explosion structure provided by the present invention.

[0016] Figure 2 This is a schematic diagram of the housing assembly provided by the present invention.

[0017] Figure 3 This is a schematic diagram of the reagent chamber assembly provided by the present invention.

[0018] Figure 4 Schematic diagram of the sampling needle assembly provided by the present invention.

[0019] Figure 5 Schematic diagram of the pump assembly provided by the present invention.

[0020] Figure 6 This is a schematic diagram of the control panel assembly provided by the present invention.

[0021] Figure 7 Schematic diagram of the chip bin assembly provided by the present invention.

[0022] Figure 8 This is a schematic diagram of the detection chip provided by the present invention.

[0023] In the picture: 1. Bottom plate; 2. Reagent chamber components; 21. Support base; 22. Reagent tube rack; 23. Reagent tube; 24. Dust cover; 241. Open and close the door; 3. Power socket assembly; 4. Sampling needle assembly; 41. Sampling needle; 42. Sampling bracket; 43. Driving mechanism; 44. Sampling needle support plate; 5. Pump assembly; 51. Three-way solenoid valve; 52. Syringe pump; 53. Diaphragm pump; 6. Control panel assembly; 61. Support sheet metal; 62. Control panel; 63. Low voltage power supply; 64. Cooling fan; 7. Chip bin assembly; 71. Detection probe; 72. Manifold; 73. Rotary valve; 74. Chip bin bracket; 75. Detection data board; 76. Chip feeding bin; 77. Chip; 771. Chip cover; 772. Chip PCB circuit layer; 773. ISFET sensor reaction area; 78. First driving mechanism; 79. Second driving mechanism; 8. Housing assembly; 81. Instrument bottom shell; 82. Instrument casing; 83. Reagent compartment door; 84. Waste liquid compartment door; 85. Chip entry and exit door; 86. Touch panel. DETAILED DESCRIPTION

[0024] It should be noted that, in the absence of conflict, the embodiments and features of the embodiments in this application can be combined with each other. The present invention will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.

[0025] It should be noted that, unless otherwise specified, all technical and scientific terms used in this application have the same meaning as commonly understood by ordinary technicians in the technical field to which this application belongs.

[0026] In the present invention, unless otherwise specified, the directional words used, such as "up, down, top, bottom", usually refer to the directions shown in the drawings, or to the components themselves in the vertical, perpendicular or gravity direction; similarly, for ease of understanding and description, "inside and outside" refer to the inside and outside relative to the outline of each component itself, but the above directional words are not used to limit the present invention.

[0027] See also Figures 1-8 As shown, an electronic microarray chip detector includes a base plate 1 and a housing assembly 8 disposed on the base plate 1. The housing assembly 8 is tightly mounted on the base plate 1 to form a closed detection space, effectively preventing the external environment from interfering with the internal detection process. The following components are disposed within the housing assembly 8: The reagent compartment component 2 is used to store NaCl solution, SSC buffer and enzyme digestion reagent.

[0028] The power socket assembly 3 is provided on a side wall of the housing assembly 8 and is used to connect an external power source to power the detector; The sampling needle assembly 4 includes a sampling needle 41 and a driving mechanism. The sampling needle 41 is used to draw reagents from the reagent chamber assembly 2. The driving mechanism is connected to the sampling needle 41 and can accurately control the moving position of the sampling needle 41.

[0029] The chip bin assembly 7 is used to place the detection chip (referred to as chip 77) and can move the chip to the detection station; a detection probe 71 is provided at the detection station, and the manifold 72 on the chip bin assembly 7 is pressed down to fit the chip and press the chip onto the detection probe 71; a rotary valve 73 is also provided in the chip bin assembly 7, and each sampling needle 41 is connected to an inlet of the rotary valve 73 through an independent pipeline, and the outlet of the rotary valve 73 is connected to the inlet of the manifold 72.

[0030] The pump assembly 5 includes a three-way solenoid valve 51 and a syringe pump 52. The syringe pump 52 is located below the detection station and generates negative pressure on the chip above it, creating a stable fluid environment inside the chip. The outlet of the manifold 72 is connected to the three-way solenoid valve 51. Based on commands from the control board assembly 6, the three-way solenoid valve 51 precisely injects different reagents into the ISFET sensor reaction area within the chip in a timed sequence.

[0031] The control panel assembly 6, serving as the core control unit of the entire detector, utilizes a high-performance microprocessor, boasting powerful data processing capabilities and stable control performance. Housed within the housing assembly 8, it is electrically connected to the power socket assembly 3, the drive mechanism of the sampling needle assembly 4, the pump assembly 5, and the chip compartment assembly 7. The control panel assembly 6 receives voltage signals from the chip compartment assembly and uploads them to the industrial computer for data analysis, enabling precise control of all equipment components and data acquisition and transmission.

[0032] Specifically, the housing assembly 8 consists of an instrument bottom shell 81 and an instrument housing 82. The instrument bottom shell 81 is closely matched with the base plate 1 described above to provide a stable bottom support for the entire device. Its material can be selected from high-strength engineering plastics to reduce the overall weight of the device and ensure structural strength.

[0033] The instrument housing 82 is covered on top of the instrument bottom housing 81 to form a closed detection space. The instrument housing 82 is provided with multiple functional doors and a touch panel 86. The reagent compartment door 83 is used to open and close the reagent compartment area to facilitate the addition or replacement of reagents. It can be connected by a hinge to achieve flexible opening and closing; the waste liquid compartment door 84 is used to treat the waste liquid generated during the detection process; the chip entry and exit compartment door 85 facilitates the placement and removal of the detection chip. These two compartment doors can also adopt a similar hinge connection structure. The touch panel 86 is electrically connected to the control panel assembly 6. The operator can input instructions, view detection data, etc. through the touch panel 86. A protective coating can be provided on its surface to enhance wear resistance and corrosion resistance.

[0034] Combine Figure 3 As shown, the reagent compartment assembly 2 includes a support base 21 fixed to the base plate 1. A reagent tube rack 22 is provided on the support base 21. The reagent tube rack 22 can be firmly connected to the support base 21 by means of a snap or slot. At least four reagent tubes 23 are provided on the reagent tube rack 22 for storing NaCl solution, SSC buffer, and enzyme digestion reagent. The reagent tubes 23 can be made of transparent glass or plastic to facilitate observation of the remaining amount of reagent inside.

[0035] A dust cover 24 is provided on the support base 21, which covers the reagent tube rack 22 and the reagent tubes 23 to prevent dust and other impurities from entering and contaminating the reagents. The dust cover 24 is provided with small holes corresponding to the reagent tubes 23, and the sampling needle 41 can be accurately inserted into the reagent tubes 23 through the small holes to extract the reagent.

[0036] To facilitate the addition and replacement of reagents, a switch door 241 is provided on one side of the dust cover 24. The switch door 241 can be connected to the dust cover 24 via a hinge for flexible opening and closing. At the same time, the reagent compartment door 83 on the housing assembly 8 corresponds to the switch door 241, making it easy for the operator to open and close it.

[0037] Combine Figure 4As shown, the sampling needle assembly 4 includes a sampling bracket 42, which is provided with a vertically distributed drive mechanism 43. The drive mechanism 43 uses a stepper motor driven lead screw module, a mature and precise transmission structure. The stepper motor has the characteristics of fast response speed and high control accuracy, and can accurately control the rotation of the lead screw.

[0038] The screw module's connecting block is tightly connected to the sampling needle support plate 44, either by threading or slotting, ensuring a secure connection and easy disassembly and maintenance. A sampling needle 41 is mounted on the sampling needle support plate 44 and secured to it via a snap or threaded connection. Driven by the drive mechanism 43, the connecting block moves vertically along the screw, thereby precisely moving the sampling needle support plate 44 and the sampling needle 41 in the vertical direction, enabling the sampling needle 41 to accurately draw reagents at varying depths within the reagent chamber assembly 2.

[0039] Combine Figure 5 As shown, a diaphragm pump 53 is also provided in the pump assembly 5. One end of the diaphragm pump 53 is connected to the cleaning liquid tank through a pipeline, and the other end is connected to the middle outlet of the rotary valve 73. When cleaning is required, the diaphragm pump 53 is started to pump the cleaning liquid from the cleaning liquid tank. After the cleaning liquid is pressurized by the diaphragm pump 53, it flows along the preset liquid pipeline, comprehensively cleaning the liquid pipeline and the inside of the chip, effectively removing residual reagents and impurities. After cleaning is completed, the waste liquid containing impurities and residual reagents is discharged from the equipment through the waste liquid port (the position of the waste liquid port corresponds to the waste liquid bin door 84). The waste liquid port can be provided with a filtering device to prevent solid impurities from clogging the subsequent waste liquid treatment system.

[0040] Combine Figure 6 As shown, the control panel assembly 6 includes a support sheet metal 61. The support sheet metal 61 can be made of a cold-rolled steel plate with a certain strength and rigidity. It is firmly installed in a suitable position in the housing assembly 8 by welding or bolting, providing reliable support for other components. A control panel 62 is provided on the support sheet metal 61, and the control panel 62 is tightly connected to the support sheet metal 61 by screws. A low-voltage power supply 63 is installed on one side of the support sheet metal 61 and is connected to the control panel 62 through a wire to provide it with a stable low-voltage power supply. The cooling fan 64 is fixed on the other side of the support sheet metal 61, close to the control panel 62. When in operation, it can accelerate the air flow, effectively take away the heat generated by the control panel 62, and ensure its stable operation.

[0041] Combine Figure 7As shown, the chip hopper assembly 7 is primarily composed of a chip hopper bracket 74, a chip feed bin 76, and a manifold 72. The chip hopper bracket 74, serving as the fundamental support structure for the entire assembly, can be constructed from a high-strength, non-deformable metal material, such as stainless steel, and is securely bolted to a specific location within the housing assembly 8. A detection data board 75 is mounted on the chip hopper bracket 74, tightly connected to the chip hopper bracket 74 via a slot. Several detection probes 71 are evenly distributed on the board. These probes are constructed from a highly conductive metal material and are used to exchange data with the chip.

[0042] The chip feed bin 76 is equipped with a chamber specifically for placing chips. The shape and size of the chamber are adapted to the chips to ensure stable chip placement. Driven by a first drive mechanism 78, the chip feed bin 76 can be smoothly moved to the inspection station. When it reaches this position, the chip placed in the chamber is directly opposite the inspection probe 71.

[0043] Driven by the second driving mechanism 79 , the busbar 72 can be pressed vertically downward until it is in close contact with the chip and firmly presses the chip 77 onto the detection probe 71 , thereby ensuring good contact between the chip and the detection probe 71 during the detection process.

[0044] In this embodiment, both the first drive mechanism 78 and the second drive mechanism 79 utilize a sophisticated and precise transmission structure driven by a stepper motor and a lead screw module. Stepper motors offer the remarkable characteristics of fast response and high control accuracy, enabling precise control of the lead screw's rotational speed and rotational speed, thereby precisely controlling the movement distance and position of the chip feed bin 76 and manifold 72, ensuring accurate and stable chip detection.

[0045] Manifold 72 is also equipped with a four-way connector. This connector is made of high-strength plastic or metal and is securely mounted on manifold 72 via a threaded connection, serving as the inlet of manifold 72. One end of the four-way connector is tightly connected to the outlet of rotary valve 73. A sealing ring is used to seal the connection to prevent liquid leakage and ensure that fluid can flow smoothly from rotary valve 73 into manifold 72, providing a stable fluid supply for subsequent testing processes.

[0046] The chip 77 in this embodiment is as follows Figure 8As shown, the chip specifically consists of a chip cover plate 771, a chip PCB circuit layer 772, and an ISFET sensor reaction area 773. This chip is a CMOS electronic chip with hundreds of thousands of microwells. Each microwell contains an ISFET sensor, which is sensitive to charge signals and can detect the voltage near the bottom of the microwell, thereby detecting chemical reactions within the microwell. Specific nucleic acid probes are covalently attached to the bottom of the microwell in the form of a dot matrix. These specific probes hybridize with target sequences in the sample and then extend after binding. This extension causes a change in charge at the bottom of the microwell, which in turn affects the voltage change of the ISFET sensor. These dot matrix areas are called positive regions, and non-dot matrix areas are called negative regions. The voltage generated by these specific probes after binding to target nucleic acids is different from the voltage of microwells without bound nucleic acid molecules and microwells in the negative region. This voltage signal can be detected by the detection probe 71.

[0047] The operation process is described as follows: When in use, first manually open the reagent compartment door 83, take out the reagent tube rack 22, and place the reagent tubes 23 containing NaCl solution, water, SSC reagent and 2×SSC reagent into the corresponding holes respectively, then place the reagent tube rack 22 into the support base 21 and close the reagent compartment door 83.

[0048] Manually click the touch panel 86, click the exit button, and then the chip feed bin 76 automatically pushes open the chip entry and exit door 85. Manually put the test chip into the chip feed bin 76, then click the screen to return, and click to start the test; The chip feed bin 76 enters the designated position under the control of the first drive mechanism 78, and then the second drive mechanism 79 operates to press the manifold 72 down to fit the chip and press the chip onto the detection probe 71; The sampling needle 41 is driven by the mechanism 43 to insert into the reagent tube 23. Finally, the rotary valve 73 and the syringe pump 52 sequentially inject different reagents into the ISFET sensor reaction area inside the chip to complete the reaction. The voltage signal detected during the reaction is transmitted to the detection data board 75 through the detection probe 71, and finally transmitted to the industrial computer for data analysis and processing, and finally the result is determined and output; After the test is completed, the diaphragm pump 53 will work to clean the entire liquid pipeline and the inside of the chip to prepare for subsequent tests. The cleaning liquid will finally be discharged through the waste liquid port. After cleaning, the manifold 72 will retract and the chip feed bin 76 will automatically be discharged. The chip can then be manually taken out or replaced.

[0049] Obviously, the embodiments described above are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts should fall within the scope of protection of the present invention.

[0050] It is to be noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments consistent with the present application. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It will be further understood that the terms "comprises" and / or "comprising," when used in this specification, specify the presence of stated features, steps, operations, devices, components and / or combinations thereof, but do not preclude the presence or addition of one or more other features, steps, operations, devices, components and / or combinations thereof.

[0051] It should be noted that the terms "first", "second", and the like, herein do not necessarily have an either chronological or spatial relation. Rather, these terms can be used solely to distinguish a certain specific entity from another entity. It should be understood that the terms "comprises", "comprising", "includes", "including" and the like used herein are specifically intended to be interpreted as specifying the presence of stated features, steps, components, devices, objects or the like, but do not preclude the presence or addition of one or more other features, steps, components, devices, objects or the like.

[0052] The preferred embodiments of the present application have been described above with the aid of drawing figures, and are not limited to those embodiments per se, but can be modified in various ways. It should be understood, therefore, that the application is not limited to the particular embodiments described herein, but is amenable to any alterations, modifications, and equivalents of the methods and apparatuses specifically taught herein. Changes can be made in the design, operation, composition and arrangement of the methods and apparatuses without departing from the scope of the present application as expressed in the following claims.

Claims

1. An electronic microarray chip detector, comprising a base plate and a housing assembly disposed on the base plate, characterized in that: The following components are arranged in the housing assembly: Reagent compartment assembly, used to store NaCl solution, SSC buffer and enzyme digestion reagent; A power socket assembly is provided on a side wall of the housing assembly and is used to connect an external power source to power the detector; The sampling needle assembly includes a sampling needle and a drive mechanism; the sampling needle is used to draw reagents from the reagent chamber assembly, and the drive mechanism is connected to the sampling needle to control the movement position of the sampling needle; The chip bin assembly is used to place the test chip and move the chip to the test station; the test station is provided with a test probe, and the manifold on the chip bin assembly is pressed down to fit the chip and press the chip onto the test probe; the chip bin assembly is also provided with a rotary valve, each of the sampling needles is connected to an inlet of the rotary valve through an independent pipeline, and the outlet of the rotary valve is connected to the inlet of the manifold; A pump assembly includes a three-way solenoid valve and a syringe pump; the syringe pump is located below the detection station and generates negative pressure on the chip above it. The outlet of the manifold is connected to the three-way solenoid valve, which injects different reagents into the ISFET sensor reaction area inside the chip in a timed manner; The control board assembly is arranged in the shell assembly and is electrically connected to the power socket assembly, the driving mechanism of the sampling needle assembly, the pump assembly and the chip bin assembly; the control board assembly receives the voltage signal from the chip bin assembly and uploads the received voltage signal to the industrial computer.

2. The electronic microarray chip detector according to claim 1, characterized in that: The reagent bin assembly includes a support base fixed on a bottom plate, a reagent tube rack is provided on the support base, and at least four reagent tubes are provided on the reagent tube rack.

3. The electronic microarray chip detector according to claim 2, characterized in that: A dust cover is provided on the support base, the reagent tube rack and the reagent tubes are located in the dust cover, and the dust cover is provided with small holes corresponding to the reagent tubes.

4. The electronic microarray chip detector according to claim 3, characterized in that: One side of the dust cover is provided with a switch door, and the housing assembly is provided with a reagent compartment door corresponding to the switch door.

5. The electronic microarray chip detector according to claim 1, characterized in that: A diaphragm pump is also provided in the pump assembly. One end of the diaphragm pump is connected to the cleaning liquid tank through a pipeline. The cleaning liquid cleans the liquid pipeline and the inside of the chip after passing through the diaphragm pump, and is finally discharged through the waste liquid port.

6. The electronic microarray chip detector according to claim 1, characterized in that: The sampling needle assembly includes a sampling bracket, which is provided with a vertically distributed driving mechanism. The driving mechanism is a screw module driven by a stepping motor. The connecting block of the screw module is connected to the sampling needle support plate, and the sampling needle is provided on the sampling needle support plate.

7. The electronic microarray chip detector according to claim 1, characterized in that: The housing assembly includes an instrument bottom shell and an instrument casing. The instrument casing is provided with a reagent compartment door, a waste liquid compartment door, a chip entry and exit compartment door and a touch panel. The touch panel is electrically connected to the control board assembly.

8. The electronic microarray chip detector according to claim 1, characterized in that: The chip bin assembly includes a chip bin bracket, a chip feed bin and a convergence plate. The chip bin bracket is provided with a detection data plate, and the detection data plate is provided with a detection probe; the chip feed bin is provided with a chamber for placing the chip, and the chip feed bin can be moved to the detection station under the drive of the first driving mechanism. At this time, the chip placed in the chamber is facing the detection probe; the convergence plate can be pressed down to be close to the chip and press the chip onto the detection probe under the drive of the second driving mechanism.

Images