Scraping lubricating oil capable of dredging channels and collaterals and preparation method thereof

Abstract

The invention discloses scraping lubricating oil capable of dredging channels and collaterals and a preparation method thereof, and relates to the technical field of traditional Chinese medicine preparations and medicine health care, the scraping lubricating oil is composed of a traditional Chinese medicine group, an antibacterial allergy-free group, a moisturizing group and an auxiliary material group, and the preparation method comprises the following steps: raw material pretreatment, active ingredient extraction, compounding and homogenizing, standing and filling inspection, filling and finished product inspection. Through synergistic compatibility of Tibetan radix salviae miltiorrhizae, tinospora sinensis merr and wormwood (tanshinone improves microcirculation, tinospora sinensis merr relieves muscle spasm, and wormwood warms and dredges meridians), and in combination with pain relieving and blood stasis removing effects of lamiophlomis rotata and saffron crocus, the product has double attributes of lubrication and treatment; clinical experiments show that after the product is used for scraping therapy for 4 weeks, the pain visual simulation score (VAS) of a rheumatism bone pain patient is reduced from 7.2 + / -1.3 to 3.1 + / -0.8, and the effective rate of dredging channels and collaterals reaches 80% or above.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of traditional Chinese medicine preparations and medical health care, in particular to a scraping lubricating oil for dredging meridians and a preparation method thereof. BACKGROUND

[0002] As a traditional Chinese medicine therapy, the theoretical basis of scraping is derived from the meridian theory of traditional Chinese medicine, which believes that there are 12 main meridians and eight extra meridians in the human body, and the circulation of qi and blood through the meridians maintains the balance of the body. When the meridians are blocked and the flow of qi and blood is not smooth, it is easy to cause pain and sub-health problems. Scraping can dilate local capillaries and open the interstices by scraping specific acupoints or meridian paths with a scraping plate, thereby promoting the excretion of "toxic substances" (toxins or pathogens in the body according to traditional Chinese medicine) and dredging the meridians and regulating the balance of qi and blood. Modern medical research has further shown that scraping can improve local microcirculation, promote the excretion of metabolic waste, and enhance the respiratory function of the skin and the body's defense ability, and has a certain effect on relieving discomfort caused by external pathogens and improving the sub-health state.

[0003] With the change of modern lifestyle, factors such as reduced physical labor, irregular life, and increased social pressure have led to the accumulation of metabolic waste and endocrine disorders in the human body, further increasing the probability of meridian blockage and microcirculation disorder, making rheumatic bone pain, muscle and bone pain, and other problems increasingly common, and people's demand for safe and effective scraping auxiliary products has significantly increased.

[0004] However, the current scraping-related products on the market have obvious technical defects and cannot meet the actual application requirements: Single function, lack of therapeutic effect: most existing scraping lubricating oils are pure oil products, which can only play a physical lubricating role and do not contain traditional Chinese medicine active ingredients, so they cannot assist in achieving the therapeutic effects of relaxing muscles and meridians, dispelling wind and removing blood stasis, etc. They are out of line with the therapeutic properties of "scraping therapy" and can only be used as an operating auxiliary medium, providing no substantial help in dredging the meridians and improving pain.

[0005] Poor safety, easy to cause skin problems: oil-based lubricating oils can easily block pores and affect normal skin respiration and metabolism if they are attached to the skin for a long time; and most products do not add bacteriostatic and anti-allergic ingredients, so repeated scraping with a scraping plate during scraping can easily cause minor skin damage, increasing the risk of allergies and infections. According to clinical observation data, the incidence of adverse reactions such as skin redness and itching when using traditional oil-based lubricating oils for scraping is as high as 18%-25%.

[0006] High operation threshold, limited applicability: existing products need to be used with professional scraping plates, and the scraping force and angle are required to be high, so non-professionals are likely to cause severe pain, abnormal bleeding, and even symptoms such as collapse when operating, which limits the popular application of the products in home scenarios. SUMMARY

[0007] The present application aims to provide a dredging meridians scraping lubricating oil and a preparation method thereof to solve the problems in the prior art.

[0008] To achieve the above-mentioned purpose, the present application provides the following technical solution: the scraping lubricating oil is composed of a traditional Chinese medicine group (60%), a bacteriostatic and anti-allergic group (10%), a moisturizing group (25%), and an auxiliary material group (5%) according to weight percentage, and the specific composition and quality requirements of each group are as follows:

[0009] The preparation method of the dredging meridians scraping lubricating oil includes four links of raw material pretreatment, active ingredient extraction, compound homogenization, and standing and filling, and the specific steps are as follows: Raw material pretreatment Thirteen kinds of traditional Chinese medicinal materials, i.e., Bupleurum scorzonerifolium, Arnebia euchroma, Saussurea involucrata, Tinospora crispa, Lamiophlomis rotata, Artemisia vulgaris, Aconitum carmichaelii, Gentiana rigescens, Salvia przewalskii, Phellodendron amurense, Glycyrrhiza uralensis, Zingiber officinale, and Rheum officinale, are removed of impurities (impurity content is controlled to be ≤0.5%), crushed by a universal crusher, sieved through an 80-mesh sieve (sieve rate ≥98%), and obtained as traditional Chinese medicinal material powder for standby use.

[0010] Extraction of active ingredients (hot water extraction-concentration process) According to the proportion of each component in the traditional Chinese medicine group, the traditional Chinese medicinal material powder is weighed, 8 times the amount of deionized water (mass ratio 1:8) is added, and the mixture is placed in a multifunctional extraction tank and heated to 95-100℃ for 2 hours of insulation extraction each time for 2 times; The two times of extraction liquid are combined, and the residual substances are removed by plate and frame filtration (filtration precision 0.22μm) to obtain a clear extraction liquid; The clear extraction liquid is transferred into a rotary evaporator and concentrated under the conditions of a vacuum degree of-0.08MPa and a temperature of 60℃ until the relative density is 1.15-1.20 (measured at 25℃) to obtain a traditional Chinese medicine concentrated extraction liquid; the total active ingredient content in the concentrated liquid is ≥15mg / mL detected by HPLC, and the concentrated liquid is standby used.

[0011] Compound and homogenization First step of compound: according to the formula proportion, the traditional Chinese medicine concentrated extraction liquid, the bacteriostatic and anti-allergic group (DP300, edible alcohol, and plant anti-allergic agent), and the moisturizing group (Aloe vera extract and hyaluronic acid) are added into a high-speed stirring tank and stirred at a speed of 1000r / min for 30 minutes until they are uniformly mixed to obtain a primary mixed liquid; Second step of vacuum homogenization: the auxiliary material group (carbomer 940 and glycerol) is added into the primary mixed liquid, and the mixture is transferred into a vacuum homogenizer, and the vacuum degree is set to-0.09MPa and the rotating speed is set to 20000r / min for 15 minutes; the viscosity is detected every 5 minutes during the homogenization to ensure that the viscosity of the final product is stably controlled in the range of 12000-14000mPa・s (25℃) to obtain a homogenized stock solution; Standing and filling inspection The homogeneous stock solution is transferred into a standing tank, and is allowed to stand for 24 hours at 25 DEG C in the dark, bubbles are removed, and the system is stabilized; Filling: the stock solution after standing is filled into plastic bottles (specification 30mL / bottle) with special scraping heads by using an automatic filling machine, the filling precision is ±0.5mL, and then the bottles are sealed; Product inspection: appearance (semi-transparent gel liquid, no stratification, no precipitation), pH value (5.5-6.5, detected by a pH meter), microbial limit (bacterial count ≤100 cfu / mL, mold and yeast count ≤10 cfu / mL, no pathogenic bacteria, meeting the requirements of the 'Cosmetic Safety Technical Specification' 2022 edition) are detected, and after the inspection is qualified, the outer package is carried out.

[0012] Compared with the prior art, the beneficial effects of the present application are: 1. Through the synergistic compatibility of Tibetan Danshen, wide-stemmed vine and wormwood (tanshinone improves microcirculation, wide-stemmed vine relieves muscle spasm, and wormwood warms the meridians and unblocks the collaterals), combined with the pain-relieving and blood-stasis-removing effects of Duiyi and safflower, the product has both lubricating and therapeutic properties; clinical experiments show that after using the product for scraping for 4 weeks, the pain visual analogue scale (VAS) of patients with rheumatic bone pain is reduced from 7.2±1.3 to 3.1±0.8, and the effective rate of unblocking the meridians is more than 80%.

[0013] 2. DP300 and 75% edible alcohol are added to inhibit bacteria, and the bacterial inhibition rate of Staphylococcus aureus and Escherichia coli is ≥99%; the plant anti-allergic agent of spilanthes acmella is matched to reduce the incidence of skin allergy from 22% of the traditional product to less than 3%; and a water-based gel system is used to avoid clogging of pores by oil, and the skin can be washed clean with water after use, and the skin breathability is improved by 60%. BRIEF DESCRIPTION OF DRAWINGS

[0014] Figure 1 It is a preparation flow chart of a meridian unblocking scraping lubricating oil. DETAILED DESCRIPTION

[0015] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0016] The present application provides a meridian unblocking scraping lubricating oil and a preparation method thereof.

[0017] Example 1

[0018] Raw material ratio (based on 1000g total formula) Traditional Chinese medicine group (600g): Muli green mao extraction liquid 50g, extraction liquid of Tibetan sage 50g, extraction liquid of Saussurea 50g, extraction liquid of wide tendon 50g, extraction liquid of only one flavor 50g, extraction liquid of wormwood 50g, extraction liquid of prepared aconite 35g, extraction liquid of Legatum 35g, extraction liquid of Tibetan salvia 50g, extraction liquid of Huangbai 50g, extraction of licorice 35g, ginger extract 25g, extract of rhubarb 25g; Bacteriostatic and anti-allergic group (100g): DP3003 35g, 75% edible alcohol 35g, plant anti-allergic agent of Portulaca oleracea 30g; Moisturizing group (250g): aloe vera extract 160g, 1000kDa hyaluronic acid 90g; Auxiliary group (50g): carbomer 9403 2g, food grade glycerol 18g.

[0019] Preparation process Raw material pretreatment: the traditional Chinese medicinal materials are crushed to pass through an 80-mesh sieve, and the impurity content is 0.3%; Hot water extraction: add water in an amount of 1:8, extract at 98℃ for 2 times (2h each time), combine the extraction liquid, filter and concentrate to a relative density of 1.18 (25℃), and the total active ingredient content is 16.2mg / mL detected by HPLC; Compound homogenization: stir the primary mixed liquid for 30 minutes (1000r / min), vacuum homogenize (20000r / min, -0.09MPa) for 15 minutes, and the final viscosity is 13200mPa・s (25℃); Standing and filling: stand at 25℃ for 24 hours, fill 30mL / bottle, and the test is qualified (pH=6.0, the microbial limit meets the standard).

[0020] Application effect experiment Experimental subjects: 50 volunteers (aged 45-65 years, VAS score≥6) diagnosed with rheumatic bone pain were randomly divided into an experimental group (40 people, using the product of the embodiment) and a control group (10 people, using traditional oil-based scraping oil); Experimental method: the experimental group was scraped once a day according to the use method of the application, and the control group was scraped in the same way, and the continuous use lasted for 4 weeks; Results: ①Symptom improvement: among the 40 people in the experimental group, 32 people had VAS scores reduced to less than 3 (effective rate 80%), and the joint mobility was improved by 35%; only 2 people in the control group had VAS scores decreased (effective rate 20%); ②Skin reaction: only 1 person in the experimental group had mild redness (adverse reaction rate 2.5%), and 3 people in the control group had redness, itching and swelling (adverse reaction rate 30%).

[0021] Example 2

[0022] Raw material ratio (according to 1000g total formula) Traditional Chinese medicine group (600g): 55g of Bupleurum smithii extract, 55g of Radix Arnebiae extract, 55g of Saussurea involucrata extract, 55g of Smilax riparia extract, 55g of Wudoumi extract, 55g of Artemisia extract, 30g of Aconitum carmichaeli extract, 30g of Lighicae extract, 55g of Radix Salviae miltiorrhizae extract, 55g of Phellodendri extract, 30g of Glycyrrhiza extract, 25g of Zingiber officinale extract, 25g of Rheum palmatum extract; Bacteriostatic and anti-allergic group (100g): 30g of DP300, 35g of 75% edible alcohol, 35g of Plant Anti-allergic Agent of Portulaca oleracea; Moisturizing group (250g): 170g of Aloe barbadensis extract, 80g of 1000kDa hyaluronic acid; Auxiliary material group (50g): 30g of Carbomer 940, 20g of food-grade glycerol.

[0023] Preparation process: consistent with example 1, the viscosity of the final product is 12800mPa・s (25℃), pH=5.8, and the microbial limit is qualified.

[0024] Application effect experiment Experimental subjects: 30 patients with lumbar spur pain (VAS score≥5); Results: After continuous use for 3 weeks, 27 people had obvious relief of stabbing pain (efficiency 90%), and the skin had no adverse reactions, proving that the product has a significant auxiliary improvement effect on old injuries, lumbar spur pain.

[0025] It is apparent to those skilled in the art that the present application is not limited to the details of the foregoing exemplary embodiments, but can be implemented in other particular forms without departing from the spirit or essential characteristics of the present application. Therefore, the embodiments should be considered in all respects as illustrative and not restrictive, and the scope of the present application is defined by the appended claims rather than the foregoing description, and it is intended to encompass all changes falling within the meaning and scope of the equivalent elements of the claims. Any reference signs in the claims should not be considered as limiting the claims involved.

Claims

1. A lubricating oil for dredging meridians and scraping, characterized by: The Chinese medicine group, the bacteriostatic and anti-allergy group, the moisturizing group and the auxiliary material group are composed.

2. The lubricating oil for dredging meridians and scraping according to claim 1, characterized in that: The Chinese medicine group includes saffron extract, artemisia rupestris extract, radix viola yedoensis extract, saussurea involucrata extract, smilax riparia extract, incarvillea potaninii extract, artemisia vulgaris extract, radix aconiti extract, radix gentianae scabra extract, radix salviae miltiorrhizae extract, phellodendri chinensis cortex extract, glycyrrhiza extract, zingiber officinale extract and rhubarb extract.

3. The lubricating oil for dredging meridians and scraping according to claim 1, characterized in that: The bacteriostatic and anti-allergy group includes DP300, edible alcohol and plant anti-allergic agent.

4. The lubricating oil for dredging meridians and scraping according to claim 1, characterized in that: The moisturizing group includes aloe vera and hyaluronic acid.

5. The lubricating oil for dredging meridians and scraping according to claim 1, characterized in that: The auxiliary material group includes carbomer and glycerol.

6. A preparation method of the meridian dredging scraping lubricating oil according to any one of claims 1-5, characterized in that, The method comprises the following steps: S1, raw material pretreatment Thirteen kinds of Chinese medicinal materials, i.e., artemisia rupestris, radix viola yedoensis, saussurea involucrata, smilax riparia, incarvillea potaninii, artemisia vulgaris, radix aconiti, radix gentianae scabra, radix salviae miltiorrhizae, phellodendri chinensis cortex, zingiber officinale and rhubarb, are removed of impurities (impurity content is controlled to be less than or equal to 0.5%), are crushed by using a universal crusher, are sieved through a 80-mesh sieve (sieve rate is greater than or equal to 98%), and are obtained as Chinese medicinal material powder for standby; S2, active ingredient extraction (hot water extraction-concentration process) According to the proportion of each component in the Chinese medicine group, the Chinese medicinal material powder is weighed, 8 times of deionized water (mass ratio 1:8) is added, and the mixture is placed in a multifunctional extraction tank and heated to 95-100 DEG C. The mixture is kept for 2 hours for 2 times of extraction. The two times of extraction liquid are combined, residual substances are removed by using a plate and frame filter (filtration accuracy is 0.22 μm), and clear extraction liquid is obtained. The clear extraction liquid is transferred into a rotary evaporator, is concentrated under the conditions of vacuum degree-0.08 MPa and temperature 60 DEG C, and is obtained as Chinese medicine concentrated extract with relative density 1.15-1.20 (25 DEG C measurement) until the end. The total active ingredient content in the concentrated extract is greater than or equal to 15 mg / mL, which is standby for use. S3, compounding and homogenization First step compounding: according to the formula proportion, the Chinese medicine concentrated extract, the bacteriostatic and anti-allergy group (DP300, edible alcohol and plant anti-allergic agent), the moisturizing group (aloe vera extract and hyaluronic acid) are added into a high-speed stirring tank, are stirred at a speed of 1000 r / min for 30 minutes until they are uniformly mixed, and are obtained as primary mixed liquid; Second step vacuum homogenization: the auxiliary material group (carbomer 940 and glycerol) is added into the primary mixed liquid, is transferred into a vacuum homogenizer, and is set to have vacuum degree-0.09 MPa and rotation speed 20000 r / min. The homogenization is performed for 15 minutes. The viscosity is detected every 5 minutes during the homogenization to ensure that the viscosity of the final product is stably controlled in the range of 12000-14000 mPa・s (25 DEG C), and the homogenized stock solution is obtained; S4, standing and filling inspection The homogenized stock solution is transferred into a standing tank, is kept at 25 DEG C and in the dark for 24 hours, and is subjected to bubble removal and system stabilization; S5, filling: the standing stock solution is filled into plastic bottles (specification 30 mL / bottle) with special scraping head by using an automatic filling machine, the filling precision is ±0.5 mL, and then the bottles are sealed; S6, finished product inspection: the appearance (semi-transparent gel liquid without stratification and precipitation), pH value (5.5-6.5, detected by using a pH meter) and microbial limit (bacterial count is less than or equal to 100 cfu / mL, mold and yeast count is less than or equal to 10 cfu / mL, and no pathogenic bacteria) of the product are detected according to the standard. After the product passes the inspection, the product is subjected to outer packaging.

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