Traditional Chinese medicine external medicine for relieving itching

Abstract

The invention discloses a traditional Chinese medicine external medicine for relieving itching, and relates to the technical field of traditional Chinese medicine external medicines. The traditional Chinese medicine composition is used for clearing away heat and toxic materials, diminishing swelling and relieving itching and effectively relieving skin inflammation and itching symptoms, the wormwood has the effects of warming channels and expelling cold and clearing damp and relieving itching and assists in improving local blood circulation of the skin, and the traditional Chinese medicine composition and the wormwood serve as main medicines to lay a powerful anti-inflammatory and channel-warming foundation; the honeysuckle and the chrysanthemum synergistically exert the effects of clearing away heat and toxic materials, resisting bacteria and diminishing inflammation, reduce skin irritation, and reduce side effects due to efficient targeted bacteria resistance; the akebiaquinata and the wood root have the effects of clearing damp and promoting diuresis, activating meridians to stop pain and promoting dampness and heat discharge, the solanum lyratum has the effects of clearing away heat and toxic materials, cooling blood and eliminating swelling, the solanum lyratum and the agastache rugosus have the effects of relieving exterior syndrome and resolving dampness, and the rabdosia lophanthide has the effects of clearing heat and promoting diuresis, so that the overall itching relieving curative effect is enhanced; relapse is prevented by adjusting the skin damp and hot environment.

Description

Technical Field

[0001] This invention relates to the field of traditional Chinese medicine external application technology, specifically to a traditional Chinese medicine external application for relieving itching. Background Technology

[0002] External application of traditional Chinese medicine refers to a class of traditional Chinese medicines primarily used externally, mainly through topical application, poultices, fumigation, eye drops, throat inhalation, and nasal drops. Some of these medicines can also be taken internally. External application medicines have the effects of detoxification and swelling reduction, promoting pus drainage, tissue regeneration and wound healing, insecticidal and antipruritic effects, hemostasis and analgesia, and are mainly used for carbuncles, boils, scabies, external injuries, burns, insect and snake bites, and diseases of the five senses (ENT).

[0003] Reference patent CN102920800B discloses a topical pharmaceutical composition comprising: 15-50 parts by weight of Coptis chinensis, 15-50 parts by weight of Scutellaria baicalensis, 20-30 parts by weight of Lithospermum erythrorhizon, 15-25 parts by weight of Carthamus tinctorius, 15-20 parts by weight of Commiphora myrrha, 15-50 parts by weight of Rheum palmatum, 50-100 parts by weight of Panax notoginseng, 15-50 parts by weight of Polygonum cuspidatum, 40-70 parts by weight of zinc oxide, 0.8 parts by weight of scopolamine, 150 parts by weight of borneol, and 320-380 parts by weight of sesame oil. This invention also discloses the application of the aforementioned topical pharmaceutical composition in the preparation of a medicament for treating skin injuries, including skin burns, scalds, scalds, skin injuries caused by radiotherapy and chemotherapy, bedsores, and skin ulcers caused by other reasons.

[0004] Patent CN104491458B discloses a topical drug composition. The topical drug composition described in this invention is a topical dosage form made from the following raw materials in the indicated weight ratios: 45-65g of *Saussurea involucrata*, 15-25g of *Angelica dahurica*, 20-30g of *Dracaena cochinchinensis*, 10-15g of frankincense, 30-45g of *Zanthoxylum nitidum*, 20-30g of myrrh, 10-25g of *Asarum heterotropoides*, 35-50g of *Polygonum cuspidatum*, 25-35g of *Bletilla striata*, 10-15g of camphor, 35-50g of *Callicarpa japonica* leaves, 15-20g of *Akebia quinata*, 20-25g of pearl powder, 10-15g of Sichuan pepper, 10-15g of *Atropurpurea*, and 35-50g of *Schefflera heptaphylla*. This drug composition is used to treat rheumatic pain, bone hyperplasia, gout, sores, bruises, burns, external ulcers, cuts, painful swellings and boils, joint pain, eczema, itching, and frostbite. While the above-mentioned medications can address skin burns, scalds, sprains, bruises, swelling and pain, rheumatoid arthritis, external ulcers, cuts, boils, joint pain, eczema, and itching to a certain extent with good therapeutic effects, their ingredients are complex, and many medicinal materials are expensive. The quality of raw materials is difficult to guarantee, increasing production costs and risks to the quality of the finished product. Therefore, we propose a traditional Chinese medicine external medication for relieving itching. Summary of the Invention

[0005] The purpose of this invention is to provide a traditional Chinese medicine for external use to relieve itching, in order to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, the present invention specifically adopts the following technical solution:

[0007] A traditional Chinese medicine for external use to relieve itching, wherein the ingredients of the external medicine are in the following weight parts: 20-25 parts of snake antler, 20-25 parts of mugwort, 1-2 parts of honeysuckle, 1-2 parts of chrysanthemum, 2-4 parts of akebia stem, 5-8 parts of purslane, 5-8 parts of white sage, 5-8 parts of patchouli, and 5-8 parts of yellow clover.

[0008] Furthermore, the weight parts of the external medicine ingredients are as follows: 20 parts of snake antler, 25 parts of mugwort, 2 parts of honeysuckle, 2 parts of chrysanthemum, 4 parts of akebia stem, 8 parts of strychnos nux-vomica, 8 parts of solanum nigrum, 8 parts of patchouli, and 8 parts of senna.

[0009] Furthermore, the weight parts of the external medicine ingredients are as follows: 22.5 parts of snake antler, 22.5 parts of mugwort, 1.5 parts of honeysuckle, 1.5 parts of chrysanthemum, 3 parts of akebia stem, 6.5 parts of strychnos nux-vomica, 6.5 parts of solanum, 6.5 parts of patchouli, and 6.5 parts of senna.

[0010] Furthermore, the weight parts of the external medicine ingredients are as follows: 25 parts of snake antler, 20 parts of mugwort, 1 part of honeysuckle, 1 part of chrysanthemum, 2 parts of akebia stem, 5 parts of strychnos nux-vomica, 5 parts of solanum lyratum, 5 parts of patchouli, and 5 parts of senna.

[0011] Furthermore, the topical medication is in the form of a wash solution and is packaged in a plastic bottle.

[0012] Furthermore, the preparation method of the topical medicine includes the following steps:

[0013] Step 1: Weigh out the raw materials of snake root, mugwort, honeysuckle, chrysanthemum, akebia stem, iris, white nightshade, patchouli, and yellow grass. Mix them according to the specified weight ratio, add 8 to 10 times the weight of water, and decoct for 1 to 2 hours while keeping it boiling to extract the active ingredients.

[0014] Step 2: Filter the decoction to remove solid residue and collect the clear filtrate;

[0015] Step 3: Heat and concentrate the filtrate to 1 / 3 to 1 / 2 of its original volume, and control the relative density at 1.10 to 1.20;

[0016] Step 4: Cool the concentrate to room temperature, add 0.1% to 0.2% sodium benzoate as a preservative, and mix well;

[0017] Step 5: Adjust the pH of the solution to 6.0-7.0 to ensure stability and obtain the washing solution;

[0018] Step 6: Sterilize the prepared washing solution by ultraviolet irradiation or high temperature instantaneous sterilization, and package and label it in a sterile environment and store it in a cool and dry place.

[0019] Step 7: Conduct finished product quality inspection, including retesting relative density, verifying pH value, checking microbial limits, and verifying preservative effect to ensure compliance with pharmacopoeia standards.

[0020] Furthermore, the topical medication is suitable for itching caused by low immunity, and should be applied once daily.

[0021] The beneficial effects of this invention are as follows:

[0022] This invention utilizes the herb *Smilax china* for clearing heat and detoxifying, reducing swelling and relieving itching, effectively alleviating skin inflammation and itching symptoms. Artemisia argyi has the effects of warming the meridians and dispelling cold, removing dampness and relieving itching, and helps improve local blood circulation in the skin. *Smilax china* and Artemisia argyi, as the main ingredients, lay the foundation for strong anti-inflammatory and meridian-warming effects. Honeysuckle and chrysanthemum work synergistically to clear heat and detoxify, and have antibacterial and anti-inflammatory effects, reducing skin irritation. Honeysuckle and chrysanthemum are highly effective in targeted antibacterial activity, reducing side effects. *Akebia quinata* and *Cephalotaxus fortunei* promote diuresis and eliminate dampness, unblock the meridians and relieve pain, promoting the expulsion of damp heat. *Solanum nigrum* clears heat and detoxifies, cools the blood and reduces swelling. Together with *Pogostemon cablin* to relieve exterior symptoms and eliminate dampness, and *Hedyotis diffusa* to clear heat and eliminate dampness, they work synergistically to enhance the overall antipruritic effect. *Akebia quinata*, *Cephalotaxus fortunei*, *Solanum nigrum*, *Pogostemon cablin*, and *Hedyotis diffusa* work synergistically to eliminate dampness, unblock the meridians and cool the blood, forming a multi-layered antipruritic mechanism that not only provides immediate relief of symptoms but also prevents recurrence by regulating the skin's damp-heat environment. Attached Figure Description

[0023] Figure 1 This is a flowchart of the preparation process of the present invention. Detailed Implementation

[0024] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings.

[0025] Please see Figure 1, the present invention provides a traditional Chinese medicine external preparation for relieving itching. The weight parts of the external preparation ingredients are as follows: 20-25 parts of Polygonum hydropiperoides, 20-25 parts of Artemisia argyi, 1-2 parts of Lonicera japonica, 1-2 parts of Chrysanthemum morifolium, 2-4 parts of Akebia quinata, 5-8 parts of Mucuna sempervirens, 5-8 parts of Solanum lyratum, 5-8 parts of Pogostemon cablin, 5-8 parts of Scutellaria barbata; among them, Polygonum hydropiperoides is used for clearing heat and detoxifying, detumescence and relieving itching, effectively relieving skin inflammation and itching symptoms; Artemisia argyi has the effects of warming the meridians and dispelling cold, removing dampness and relieving itching, and assisting in improving local skin blood circulation; Lonicera japonica and Chrysanthemum morifolium work together to clear heat and detoxify, antibacterial and anti-inflammatory, reducing skin irritation; Akebia quinata and Mucuna sempervirens promote diuresis and remove dampness, dredge collaterals and relieve pain, promoting the excretion of dampness and heat; Solanum lyratum clears heat and detoxifies, cools blood and detumescence, and synergizes with Pogostemon cablin to relieve exterior syndrome and resolve dampness, and Scutellaria barbata to clear heat and promote diuresis, jointly enhancing the overall itching relief effect. The above material combination optimizes the synergistic effect of each ingredient through precise weight ratio. Polygonum hydropiperoides and Artemisia argyi, as the main drugs, account for 20-25 parts, laying a foundation for strong anti-inflammatory and warming the meridians; although Lonicera japonica and Chrysanthemum morifolium are only 1-2 parts, they are highly targeted for antibacterial, reducing side effects; Akebia quinata, Mucuna sempervirens, Solanum lyratum, Pogostemon cablin and Scutellaria barbata synergistically promote diuresis, dredge collaterals and cool blood within the range of 5-8 parts, forming a multi-level itching relief mechanism, not only immediately relieving symptoms, but also preventing recurrence by regulating the dampness and heat environment of the skin.

[0026] Polygonum hydropiperoides, recorded in the 2020 edition of the Chinese Pharmacopoeia: Nature, taste and meridian tropism: sour, bitter, flat, belonging to the lung and small intestine meridians; Functions and indications: It has the effects of clearing heat and detoxifying, diuretic and detumescence;

[0027] Artemisia argyi, recorded in the 2020 edition of the Chinese Pharmacopoeia: Nature, taste and meridian tropism: pungent, bitter, warm; belonging to the liver, spleen and kidney meridians; Functions and indications: It has the effects of warming the meridians to stop bleeding, dispelling cold and relieving pain, removing dampness and relieving itching;

[0028] Lonicera japonica, recorded in the 2020 edition of the Chinese Pharmacopoeia: Nature, taste and meridian tropism: sweet, cold, belonging to the lung, heart and stomach meridians; Functions and indications: Clearing heat and detoxifying, dispersing wind and heat. For carbuncles, sores and boils, throat obstruction, erysipelas, heat-toxic dysentery, wind-heat cold, febrile disease with fever;

[0029] Chrysanthemum morifolium, recorded in the 2020 edition of the Chinese Pharmacopoeia: Nature, taste and meridian tropism: sweet, bitter, slightly cold, belonging to the lung and liver meridians; Functions and indications: Dispelling wind and clearing heat, soothing the liver and improving eyesight, clearing heat and detoxifying. For wind-heat cold, headache and dizziness, red and swollen eyes, dim eyesight, sores and carbuncles;

[0030] Akebia quinata, recorded in the 2020 edition of the Chinese Pharmacopoeia: Nature, taste and meridian tropism: bitter, cold, belonging to the heart, small intestine and bladder meridians; Functions and indications: Diuretic and stranguria-relieving, clearing heart and relieving restlessness, dredging channels and promoting lactation. For stranguria, edema, vexation with painful urination, sores and ulcers in the mouth and tongue, amenorrhea and less lactation, damp-heat arthralgia;

[0031] Mucuna sempervirens, recorded in the 2020 edition of the Chinese Pharmacopoeia: Nature, taste and meridian tropism: warm in nature, sour in taste, belonging to the liver and spleen meridians; Functions and indications: The effects of dispersing wind and clearing heat, relieving muscle spasms and removing nebula;

[0032] According to the 2020 edition of the Chinese Pharmacopoeia, the properties and channels of Bai Ying are: bitter and sweet in taste, cold in nature, and enters the liver and stomach channels; functions and indications: clearing heat and detoxifying, promoting diuresis and reducing swelling.

[0033] According to the 2020 edition of the Chinese Pharmacopoeia, the properties and channels of Agastache rugosa are: pungent and warm, entering the spleen, stomach, and lung channels; its functions and indications are: relieving exterior symptoms, resolving dampness, and stopping vomiting.

[0034] According to the 2020 edition of the Chinese Pharmacopoeia, Huangxi grass has the following properties and channels: bitter and cold in nature, and enters the liver, gallbladder, and large intestine channels. Its functions and indications are: clearing heat and dampness, cooling blood, and dispersing blood stasis.

[0035] Example 1

[0036] The preparation method of topical medications includes the following steps:

[0037] Step 1: Weigh out the raw materials of snake root, mugwort, honeysuckle, chrysanthemum, akebia stem, sedge, solanum, patchouli, and yellow grass, and mix them according to the specified weight ratio: snake root 20 parts, mugwort 25 parts, honeysuckle 2 parts, chrysanthemum 2 parts, akebia stem 4 parts, sedge 8 parts, solanum 8 parts, patchouli 8 parts, and yellow grass 8 parts. After mixing, add 8 to 10 times the weight of water, decoct for 1 to 2 hours, keeping it boiling, in order to extract the effective ingredients.

[0038] Step 2: Filter the decoction to remove solid residue and collect the clear filtrate;

[0039] Step 3: Heat the filtrate to concentrate it to 1 / 3 to 1 / 2 of its original volume, and control the relative density at 1.10 to 1.20 (measured at 60℃);

[0040] Step 4: Cool the concentrate to room temperature, add 0.1% to 0.2% sodium benzoate as a preservative, and mix well;

[0041] Step 5: Adjust the pH of the solution to 6.0-7.0 to ensure stability and obtain the washing solution;

[0042] Step 6: Sterilize the prepared washing solution by ultraviolet irradiation or high temperature instantaneous sterilization, and package and label it in a sterile environment and store it in a cool and dry place.

[0043] Step 7: Conduct finished product quality inspection, including retesting relative density (1.10~1.20 at 60℃), verifying pH value (6.0~7.0), checking microbial limits, and verifying preservative effect to ensure compliance with pharmacopoeia standards.

[0044] In this embodiment, preferably, the topical medication is suitable for itching caused by low immunity, and should be applied once daily.

[0045] Example 2

[0046] The preparation method of topical medications includes the following steps:

[0047] Step 1: Weigh out the raw materials of snake root, mugwort, honeysuckle, chrysanthemum, akebia stem, sedge, solanum, patchouli, and yellow grass, and mix them according to the specified weight ratio: snake root 22.5 parts, mugwort 22.5 parts, honeysuckle 1.5 parts, chrysanthemum 1.5 parts, akebia stem 3 parts, sedge 6.5 parts, solanum 6.5 parts, patchouli 6.5 parts, and yellow grass 6.5 parts. After mixing, add 8 to 10 times the weight of water, decoct for 1 to 2 hours, keeping it boiling, in order to extract the effective ingredients.

[0048] Step 2: Filter the decoction to remove solid residue and collect the clear filtrate;

[0049] Step 3: Heat the filtrate to concentrate it to 1 / 3 to 1 / 2 of its original volume, and control the relative density at 1.10 to 1.20 (measured at 60℃);

[0050] Step 4: Cool the concentrate to room temperature, add 0.1% to 0.2% sodium benzoate as a preservative, and mix well;

[0051] Step 5: Adjust the pH of the solution to 6.0-7.0 to ensure stability and obtain the washing solution;

[0052] Step 6: Sterilize the prepared washing solution by ultraviolet irradiation or high temperature instantaneous sterilization, and package and label it in a sterile environment and store it in a cool and dry place.

[0053] Step 7: Conduct finished product quality inspection, including retesting relative density (1.10~1.20 at 60℃), verifying pH value (6.0~7.0), checking microbial limits, and verifying preservative effect to ensure compliance with pharmacopoeia standards.

[0054] In this embodiment, preferably, the topical medication is suitable for itching caused by low immunity, and should be applied once daily.

[0055] Example 3

[0056] The preparation method of topical medications includes the following steps:

[0057] Step 1: Weigh out the raw materials of snake root, mugwort, honeysuckle, chrysanthemum, akebia stem, sedge, solanum, patchouli, and yellow grass, and mix them according to the specified weight ratio: snake root 25 parts, mugwort 20 parts, honeysuckle 1 part, chrysanthemum 1 part, akebia stem 2 parts, sedge 5 parts, solanum 5 parts, patchouli 5 parts, and yellow grass 5 parts. After mixing, add 8 to 10 times the weight of water, decoct for 1 to 2 hours, keeping it boiling, in order to extract the effective ingredients.

[0058] Step 2: Filter the decoction to remove solid residue and collect the clear filtrate;

[0059] Step 3: Heat the filtrate to concentrate it to 1 / 3 to 1 / 2 of its original volume, and control the relative density at 1.10 to 1.20 (measured at 60℃);

[0060] Step 4: Cool the concentrate to room temperature, add 0.1% to 0.2% sodium benzoate as a preservative, and mix well;

[0061] Step 5: Adjust the pH of the solution to 6.0-7.0 to ensure stability and obtain the washing solution;

[0062] Step 6: Sterilize the prepared washing solution by ultraviolet irradiation or high temperature instantaneous sterilization, and package and label it in a sterile environment and store it in a cool and dry place.

[0063] Step 7: Conduct finished product quality inspection, including retesting relative density (1.10~1.20 at 60℃), verifying pH value (6.0~7.0), checking microbial limits, and verifying preservative effect to ensure compliance with pharmacopoeia standards.

[0064] In this embodiment, preferably, the topical medication is suitable for itching caused by low immunity, and should be applied once daily.

[0065] The above description of the disclosed embodiments enables those skilled in the art to make or use the invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the invention. Therefore, the invention is not to be limited to the embodiments shown herein, but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A traditional Chinese medicine for external use to relieve itching, characterized in that, The ingredients of the external medicine are in the following weight proportions: 20-25 parts of snake antler, 20-25 parts of mugwort, 1-2 parts of honeysuckle, 1-2 parts of chrysanthemum, 2-4 parts of akebia stem, 5-8 parts of purslane, 5-8 parts of solanum, 5-8 parts of patchouli, and 5-8 parts of senna.

2. The traditional Chinese medicine for external use to relieve itching according to claim 1, characterized in that, The ingredients of the external medicine are in the following weight proportions: 20 parts snake antler, 25 parts mugwort, 2 parts honeysuckle, 2 parts chrysanthemum, 4 parts akebia stem, 8 parts strychnos nux-vomica, 8 parts solanum lyratum, 8 parts patchouli, and 8 parts senna.

3. A traditional Chinese medicine for external use to relieve itching according to claim 1, characterized in that, The ingredients of the external medicine are in the following weight proportions: 22.5 parts of snake antler velvet, 22.5 parts of mugwort, 1.5 parts of honeysuckle, 1.5 parts of chrysanthemum, 3 parts of akebia stem, 6.5 parts of strychnos nux-vomica, 6.5 parts of solanum nigrum, 6.5 parts of patchouli, and 6.5 parts of senna.

4. A traditional Chinese medicine for external use to relieve itching according to claim 1, characterized in that, The ingredients of the external medicine are in the following weight proportions: 25 parts snake antler, 20 parts mugwort, 1 part honeysuckle, 1 part chrysanthemum, 2 parts akebia stem, 5 parts strychnos nux-vomica, 5 parts solanum lyratum, 5 parts patchouli, and 5 parts senna.

5. A traditional Chinese medicine for external use to relieve itching according to claim 1, characterized in that, The topical medication is in the form of a wash solution and is packaged in a plastic bottle.

6. A traditional Chinese medicine for external use to relieve itching according to claim 1, characterized in that, The preparation method of the topical medicine includes the following steps: Step 1: Weigh out the raw materials of snake root, mugwort, honeysuckle, chrysanthemum, akebia stem, iris, white nightshade, patchouli, and yellow grass. Mix them according to the specified weight ratio, add 8 to 10 times the weight of water, and decoct for 1 to 2 hours while keeping it boiling to extract the active ingredients. Step 2: Filter the decoction to remove solid residue and collect the clear filtrate; Step 3: Heat and concentrate the filtrate to 1 / 3 to 1 / 2 of its original volume, and control the relative density at 1.10 to 1.20; Step 4: Cool the concentrate to room temperature, add 0.1% to 0.2% sodium benzoate as a preservative, and mix well; Step 5: Adjust the pH of the solution to 6.0-7.0 to ensure stability and obtain the washing solution; Step 6: Sterilize the prepared washing solution by ultraviolet irradiation or high temperature instantaneous sterilization, and package and label it in a sterile environment and store it in a cool and dry place. Step 7: Conduct finished product quality inspection, including retesting relative density, verifying pH value, checking microbial limits, and verifying preservative effect to ensure compliance with pharmacopoeia standards.

7. A traditional Chinese medicine for external use to relieve itching according to claim 1, characterized in that, The topical medication is suitable for itching caused by low immunity and should be applied once daily.

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