Production device and process for thin film coated tablets of colquhoumia root tablets
By designing a coating pan device with ventilation slots and a blower, the problems of high cleaning and maintenance costs and coating liquid waste caused by fine drug powder were solved, achieving efficient drug powder recovery and finished product unloading, thus improving production efficiency and product quality.
Patent Information
- Application Number
- CN202511337201.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-09-18
- Publication Date
- 2025-11-18
AI Technical Summary
Traditional production processes for Torchflower Root Tablets with film coating suffer from several problems, including increased cleaning and maintenance costs due to fine drug powder, waste of coating solution, difficulty in material recycling, and challenges in material unloading.
Design a production device for film-coated tablets of Torchflower Root Tablets. The device uses a coating pan with ventilation slots, a blower to adsorb fine drug powder, and a sliding strip and a sealing plate to achieve real-time extraction of drug powder and convenient feeding of finished products.
It reduces the intensity and time cost of cleaning work, reduces equipment wear and maintenance frequency, improves yield and quality, reduces waste disposal costs, and achieves efficient recycling and environmentally friendly treatment of pharmaceutical raw materials.
Smart Images
Figure CN120960049A_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The application relates to the technical field of traditional Chinese medicinal material processing, and particularly discloses a production device and process for Malveiflorae root tablet film-coated tablets. BACKGROUND
[0002] The Malveiflorae root tablet is a modern traditional Chinese medicine preparation widely used in clinical practice, and has the main effects of treating rheumatoid arthritis, systemic lupus erythematosus, psoriasis and other autoimmune diseases. Currently, the commercially available Malveiflorae root tablets are mostly plain tablets, which have relatively low production cost, but have poor taste and are easy to absorb moisture, thereby affecting the stability and shelf life of the medicine. In order to overcome the defects of the plain tablets, the film-coating technology has been introduced into the production of the Malveiflorae root tablets. The film-coated tablets not only can cover the bad smell of the medicine, improve the taste, and be easy to swallow, but also can improve the moisture-proof, light-proof and wear-resistant performance of the tablets, and significantly enhance the stability and appearance of the medicine. Therefore, the film-coated tablets have become an important development direction of modern pharmacy.
[0003] Currently, the main production process of the Malveiflorae root tablet film-coated tablets is as follows: taking the Malveiflorae root plain tablet as the tablet core, dissolving the film-forming material, plasticizer, colorant and the like in a suitable solvent to prepare a coating liquid, and then coating the coating liquid on the surface of the continuously rolling tablet core in a coating pan device by spraying, so that a uniform film coating layer is formed after drying, and finally the coated tablet is obtained.
[0004] However, in the process of producing the coated tablets by using the traditional coating pan, the tablet core needs to be preheated and dried before the coating operation, and the coating pan needs to be continuously turned during this period to make the tablet core evenly heated. During the turning process, the tablet cores with hard texture frequently collide and rub with each other and with the inner wall of the metal coating pan, and inevitably generate fine powder or particle debris of the medicine.
[0005] The powder will continuously accumulate in the coating pan, which brings a series of problems, for example: the accumulated powder adheres to the wall of the pan, the spray gun and the ventilation system, and a large amount of manpower and time is needed to thoroughly clean after each batch of production, otherwise the quality of the next batch of products will be affected, and the risk of equipment failure will be increased; and during the spraying process, part of the coating liquid will combine with the powder floating or adhering to the surface of the tablet core instead of being completely and effectively coated on the tablet core. This not only leads to the waste of the coating material, increases the production cost, but also may form a rough and incomplete film coating due to the wrapping of the dust, thereby affecting the appearance and quality of the coated tablet; meanwhile, the powder mixed with the coating liquid components becomes a new kind of waste, which has complex components and is difficult to separate and recycle, thereby increasing the subsequent waste treatment cost and environmental protection pressure.
[0006] And the traditional coating pot is mostly loaded and unloaded from the pot opening, for the coating pot with fixed pot opening, the finished product coating tablet needs to be taken out from the coating pot manually, the working environment is poor, and the labor intensity is high; the pot opening of part of the coating pot can be turned over, although the unloading is convenient and fast, but the overall driving structure is complex and tedious, the structural strength and reliability are poor, and the cost is high.
[0007] Therefore, in the current production process of firecracker flower root tablet film-coated tablets, due to the fine powder of the medicine, there are problems such as increased cleaning and maintenance cost, waste of coating liquid, high difficulty in material recovery, and difficulty in unloading of finished coating tablets, therefore, the present application provides a firecracker flower root tablet film-coated tablet production device and process to solve the above problems. SUMMARY
[0008] The purpose of the present application is to solve the problems of increased cleaning and maintenance cost, waste of coating liquid, and difficulty in recovery in the production process of traditional firecracker flower root tablet film-coated tablets due to fine powder of the medicine.
[0009] In order to achieve the above purpose, the basic scheme of the present application provides a firecracker flower root tablet film-coated tablet production device, which comprises a rack, a coating pot inclinedly arranged on the rack, a driving mechanism for driving the coating pot to rotate, a hot air pipeline and a coating liquid pipeline respectively extending into the coating pot for supplying hot air and coating liquid; The side wall of the coating pot is uniformly provided with ventilation grooves along the axis of the coating pot rotation axis, the width of the ventilation grooves is less than the thickness of the firecracker flower tablet core, the rack is provided with a support sleeve covering the ventilation grooves, the outer wall of the coating pot is rotationally connected with the support sleeve, the support sleeve is provided with an air bellow communicated with the ventilation grooves, and the rack is provided with a blower, the air inlet end of the blower is communicated with the air bellow.
[0010] The principle and effect of the basic scheme are: Compared with the prior art, the device can absorb the fine powder of the medicine from the ventilation grooves in real time through the wind power of the blower during the drying and preheating of the firecracker flower root tablet core by the coating pot, so that the fine powder of the medicine is no longer accumulated in the coating pot and the spray gun, the cleaning work intensity after each batch of production is greatly reduced, the labor and time cost is saved, the equipment wear is reduced, the long-period maintenance frequency and cost of the equipment are reduced, the quality problems such as pitting, blistering or peeling caused by the embedding of the fine powder into the film are effectively prevented, the rejection rate and rework rate are reduced, and the yield of the production process and the output of high-quality products are improved; at the same time, the collected fine powder is relatively pure medicine raw material, which is easier and more economical to recycle or centrally and legally treated, and the burden and cost of waste treatment are reduced.
[0011] Further, the coating pan comprises a first pan body and a second pan body respectively rotatably connected with the supporting sleeve, a notch is formed between the second pan body and the second pan body, and a plurality of connecting tabs are arranged between the first pan body and the second pan body. The wind box is provided with a plurality of fixing strips located in the notch gap. The first gap with a width less than the thickness of the firework core is formed between the fixing strips and the first pan body and the second pan body. By arranging the first pan body, the second pan body and the connecting tabs, the strength of the coating pan is ensured, and the drug powder in the coating pan can be easily sucked out by the air blower.
[0012] Further, the notch between adjacent fixing strips is formed to have a width greater than the diameter of the firework core, and the wind box is slidably connected with a sliding strip extending into the notch. The wind box is provided with a discharging box in communication with the discharging slot. By adjusting the cooperation relationship between the sliding strip and the fixing strip, the sliding strip extends into or out of the discharging slot, so that the discharging slot is blocked or opened, so that the notch between the first pan body and the second pan body can not only be used for sucking out the drug powder, but also be used for discharging the finished firework root film coated tablets, replacing the traditional discharging at the notch of the coating pan. The discharging can be realized in a lower cost and more convenient driving mode. The overall structure is compact and convenient, the structural stability is high, and the control cost is low.
[0013] Further, the second gap with a width less than the thickness of the firework core is formed between the fixing strip and the sliding strip. The sucking effect of the air blower on the drug powder in the coating pan is further improved.
[0014] Further, the inner wall of the supporting sleeve is further provided with a sealing strip embedded in the notch, and the two ends of the sealing strip are closed connected with the two ends of the fixing strip. In order to prevent the firework root core from being stuck in the dead angle in the coating pan.
[0015] Further, it further comprises a conversion assembly for driving the sliding strip to slide in the wind box, comprising a linear driving member and a sliding frame driven by the linear driving member, and the sliding frame is connected with each sliding strip. In order to facilitate the sliding of the sliding strip, and further facilitate the adjustment of the cooperation relationship between the sliding strip and the fixing strip.
[0016] Further, the bottom of the sliding frame is further provided with a sealing plate capable of blocking the connection between the feeding box and the air box, when the sliding strip extends into the feeding groove, the sealing plate blocks the connection between the feeding box and the air box; when the sliding plate extends out of the feeding groove, the feeding box is communicated with the air box. By arranging the sealing plate, when the firecracker flower root tablet core is dried and preheated, the sliding strip extends into the feeding groove to block the feeding groove, and the sealing plate blocks the connection between the feeding box and the air box, so that a relatively closed environment is formed in the air box which is communicated with the ventilation groove and the air blower, preventing the air in the feeding box from being sucked by the air blower, thereby improving the adsorption effect of the air blower on the drug dust, and when the finished firecracker flower root tablet film-coated tablet is fed, the inclined sealing plate can guide the falling finished firecracker flower root tablet film-coated tablet, preventing the finished firecracker flower root tablet film-coated tablet from piling up.
[0017] Further, the sliding frame is provided with a baffle capable of blocking the connection between the air blower and the air box, when the sliding strip extends into the feeding groove, the air blower is communicated with the air box; when the sliding plate extends out of the feeding groove, the sealing plate blocks the connection between the air blower and the air box. The arrangement of the baffle makes the baffle block the connection between the air blower and the air box when the finished firecracker flower root tablet film-coated tablet is fed, so as to separate the air box and the air blower, preventing the finished firecracker flower root tablet film-coated tablet from being sucked by the air blower.
[0018] Based on the same inventive concept, the present application discloses a production process of firecracker flower root tablet film-coated tablet, which comprises using the above-mentioned production device to produce and process firecracker flower root tablet film-coated tablet, and the steps are as follows: Step S1, preparing firecracker flower root tablet core; Step S2, preparing firecracker flower root tablet film-coating liquid; Step S3, using the coating pot in the above-mentioned production device to dry and preheat the firecracker flower root tablet core, and using the air blower to suck out the drug fine powder from the ventilation groove; Step S4, uniformly spraying the prepared firecracker flower root tablet film-coating liquid to the preheated firecracker flower root tablet core through the coating liquid pipeline, so as to form a film coating layer on the surface of the firecracker flower root tablet core, i.e. the firecracker flower root tablet film-coated tablet is obtained.
[0019] Further, in step S1, the preparation of firecracker flower root extract, granulation, drying and granulation, mixing and tabletting are sequentially performed, wherein the step of preparing firecracker flower root extract is: taking firecracker flower root, cutting into thin slices, decocting multiple times with water, filtering the combined decoction, concentrating the filtrate to a clear extract with a relative density of 1.05-1.07 at 60℃, adding ethanol to make the alcohol content of the clear extract reach 70%, stirring uniformly, standing for 12 hours, filtering again, recovering ethanol from the filtrate and concentrating to a thick extract with a relative density of 1.30-1.35 at 60℃.
[0020] Compared with the prior art, in the process of drying and preheating the core of the firecracker flower root tablet in the coating pan, the drug fine powder can be sucked out from the ventilation groove in real time through the wind suction of the air blower, so that the drug dust is no longer accumulated in the coating pan and the spray gun, the cleaning work intensity after each batch of production is greatly reduced, the manpower and time cost are saved, the equipment wear is reduced, and the long-period maintenance frequency and cost of the equipment are reduced; and the quality problems such as pitting, blistering or peeling caused by the dust embedded in the film are effectively prevented, the defective rate and the rework rate are reduced, and thus the yield of the production process and the output of high-quality products are improved; meanwhile, the collected dust is relatively pure drug raw materials, which makes it easier and more economical to recycle or conduct centralized and compliant environmental protection treatment, and reduces the burden and cost of waste treatment. BRIEF DESCRIPTION OF DRAWINGS
[0021] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the embodiment description will be briefly introduced. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor.
[0022] Figure 1 A schematic diagram of a firecracker flower root tablet film-coated tablet production device is shown. Figure 2 A side view of a firecracker flower root tablet film-coated tablet production device is shown. Figure 3 A cross-sectional view of a coating pan in a firecracker flower root tablet film-coated tablet production device is shown. Figure 4 A cross-sectional view of a wind box in a firecracker flower root tablet film-coated tablet production device is shown. Figure 5 A Figure 4 A portion A of the cross-sectional view is enlarged. DETAILED DESCRIPTION
[0023] In order to further illustrate the technical means and effects adopted by the present application to achieve the predetermined invention purpose, the specific embodiments, structures, features and effects according to the present application will be described in detail below with reference to the drawings and preferred embodiments.
[0024] The reference signs in the drawings of the specification include: rack 1, coating pot 2, first pot body 201, second pot body 202, connecting lug 203, support sleeve 3, supply pipeline 4, spraying plate 5, air bellow 6, discharging box 7, chute 8, air inlet branch pipe 9, linear driving member 10, rotating shaft 11, sliding rod 12, sliding frame 13, sealing plate 14, slot 15, baffle 16, air inlet 17, fixing strip 18, sliding strip 19.
[0025] A production device for Gypsophila Echinata L. root slice film-coated tablets, as shown in the drawings, comprises a rack 1, a support sleeve 3 obliquely arranged on the rack 1, a coating pot 2 rotationally connected with the support sleeve 3, a driving mechanism for driving the coating pot 2 to rotate, and a supply pipeline 4 extending into the coating pot 2. Figure 1 Figure 2 The driving mechanism comprises a motor arranged on the rack 1 and a speed reducer driven by the motor, the output shaft of the speed reducer is connected with the end of the second pot body 202 through a rotating shaft 11, and drives the second pot body 202, the connecting lug 203 and the first pot body 201 to rotate, that is, drives the whole coating pot 2 to rotate.
[0026] The coating pot 2 comprises a first pot body 201, a second pot body 202 and a plurality of connecting lugs 203 for connecting the first pot body 201 and the second pot body 202, the connecting lugs 203 are directly welded and fixed or bolted with the first pot body 201 and the second pot body 202. The first pot body 201 and the second pot body 202 form an annular slot 15.
[0027] The driving mechanism comprises a motor arranged on the rack 1 and a speed reducer driven by the motor, the output shaft of the speed reducer is connected with the end of the second pot body 202 through a rotating shaft 11, and drives the second pot body 202, the connecting lug 203 and the first pot body 201 to rotate, that is, drives the whole coating pot 2 to rotate.
[0028] The supply pipeline 4 is respectively wrapped with a hot air pipeline and a coating liquid pipeline, the hot air pipeline is communicated with a hot air blower to supply hot air into the coating pot 2, the coating liquid pipeline is communicated with a liquid pump to supply coating liquid into the coating pot 2, the supply pipeline 4 extends into the coating pot 2 and is connected with a spraying plate 5, the spraying plate 5 is hollow and partitioned to form chambers communicated with the hot air pipeline and the coating liquid pipeline respectively, and a plurality of spraying openings communicated with the chambers are arranged at the bottom of the spraying plate 5.
[0029] As shown in the drawings, Figure 3 Figure 4 The bottom of the support sleeve 3 is provided with an air bellow 6, and the bottom of the air bellow 6 is provided with a discharging box 7. The bottom of the discharging box 7 is provided with a chute 8, and the support sleeve 3 is connected and fixed with the rack 1 through the air bellow 6 and the discharging box 7, thereby improving the supporting effect of the coating pot 2 and improving the overall structural strength and stability.
[0030] The inner wall of the supporting sleeve 3 is provided with a sealing strip embedded in the notch 15 between the first kettle body 201 and the second kettle body 202, and the top of the air bellow 6 is provided with a fixed strip 18 embedded in the notch 15 between the first kettle body 201 and the second kettle body 202, and the two ends of the sealing strip are closedly connected with the two ends of the fixed strip 18, forming an annular structure covering the notch 15, and the air bellow 6 is slidably connected with sliding strips 19 respectively extending into the discharge chute, the first gap is formed between the fixed strip 18 and the first kettle body 201 and the second kettle body 202, and the second gap is formed between the fixed strip 18 and the sliding strip 19, the width of the first gap and the second gap is smaller than the thickness of the Gypsophila oldhamiana core, serving as a ventilation groove for connecting the coating kettle 2 with the air bellow 6, and the width of the discharge chute formed between adjacent fixed strips 18 is greater than the diameter of the Gypsophila oldhamiana core, so as to connect the coating kettle 2 with the air bellow 6, the discharge chute 7 and the chute 8.
[0031] The air bellow is arranged in the rack 1, and the air inlet end of the air bellow is communicated with the air bellow 6 through a plurality of air inlet branch pipes 9, and correspondingly, the side wall of the air bellow 6 is provided with a plurality of air inlets 17 communicated with the air inlet branch pipes 9.
[0032] The device can absorb the drug fine powder from the ventilation groove in real time through the air power of the air bellow during the process of drying and preheating the Gypsophila oldhamiana core in the coating kettle 2, which can greatly reduce the cleaning work intensity after each batch of production, save the labor and time cost, reduce the equipment wear and tear, and reduce the long-period maintenance frequency and cost of the equipment; secondly, it effectively prevents the quality problems such as pitting, blistering or peeling caused by the embedding of dust into the film, reduces the rate of defective products and rework, and improves the yield of the production process and the output of high-quality products; thirdly, the collected dust is relatively pure drug raw materials, which makes it easier and more economical to recycle or conduct centralized and compliant environmental protection treatment, thereby reducing the burden and cost of waste treatment; it can be seen that the device has made positive technical progress in multiple dimensions such as quality, cost, efficiency, environmental protection and safety, and provides strong technical support for the modern production of the Gypsophila oldhamiana film-coated tablet.
[0033] In one embodiment, the sliding strip 19 is driven to slide through a conversion assembly, and the conversion assembly includes a linear driving member 10 and a sliding frame 13 driven by the linear driving member 10, wherein the linear driving member 10 adopts any one of a pneumatic cylinder, a hydraulic cylinder or an electric telescopic rod, and is installed outside the air bellow 6, the output end of the linear driving member 10 is fixedly installed with a sliding rod 12, the sliding rod 12 extends into the air bellow 6 and is connected with the sliding frame 13, correspondingly, the side wall of the air bellow 6 is provided with a sliding groove accommodating the sliding of the sliding rod 12, and the sliding frame 13 is respectively connected with each sliding strip 19.
[0034] The linear driving member 10 facilitates the sliding of the sliding rod 12, and the sliding groove limits and guides the sliding rod 12, so as to drive the sliding bar 19 to adjust the position, and then facilitate the adjustment of the cooperation between the sliding bar 19 and the fixed bar 18.
[0035] In one of the embodiments, the sliding frame 13 comprises a connecting plate and a blocking plate, the blocking plate is connected with the sliding rod 12, and the distance between the top of the blocking plate and the bottom of the blocking plate and the sliding rod 12 is greater than the length of the sliding groove; the connecting plate is arranged in the air bellow 6 and is arranged along the horizontal plane; the connecting plate and the blocking plate are connected through a plurality of first connecting rods, the length of the first connecting rod is greater than the diameter of the Gypsophila oldhamiana core; and the connecting plate and each sliding bar 19 are connected through a plurality of second connecting rods.
[0036] The connection between the sliding frame 13 and the sliding bar 19 is facilitated, and meanwhile, the sliding groove is prevented from connecting the inside and outside of the air bellow 6 during the sliding of the sliding frame 13, so as to affect the adsorption effect of the air blower.
[0037] In one of the embodiments, the connecting plate is further connected with a sealing plate 14 through a plurality of third connecting rods, the sealing plate 14 is arranged along the horizontal plane and can block the connection between the air bellow 6 and the blanking box 7; and the bottom of the blocking plate is connected with a baffle 16, the baffle 16 can block the air inlet 17 at the connection between the air blower and the air bellow 6.
[0038] When the sliding bar 19 extends into the blanking groove, the sealing plate 14 blocks the connection between the air bellow 6 and the blanking box 7, and the air blower is connected with the air bellow 6, so that a relatively closed environment is formed in the air bellow 6 during the drying and preheating of the Gypsophila oldhamiana core, the air in the blanking box 7 is prevented from being adsorbed by the air blower, and the adsorption effect of the air blower on the medicine dust is improved; when the sliding bar 19 extends out of the blanking groove, the blanking box 7 is connected with the air bellow 6, and the baffle 16 blocks the air inlet 17, so as to separate the air bellow 6 and the air blower, and prevent the finished Gypsophila oldhamiana film-coated tablet from being adsorbed by the air blower.
[0039] Based on the same inventive concept, one of the embodiments of the present application provides a production process of the Gypsophila oldhamiana film-coated tablet, which comprises the production and processing of the Gypsophila oldhamiana film-coated tablet by using the above production device, and the steps are as follows: Step S1, preparing the Gypsophila oldhamiana core, specifically as follows: Step S11, preparing the Gypsophila oldhamiana extract, taking the Gypsophila oldhamiana, cutting into thin slices, and decocting three times with water, 1.5 hours for the first time, 1 hour for each of the second and third times, filtering the combined decoction, concentrating the filtrate to a clear extract with a relative density of 1.05-1.07 (60℃), adding ethanol to make the alcohol content of the clear extract reach 70%, stirring uniformly, standing for 12 hours, filtering again, recovering ethanol from the filtrate and concentrating to a thick extract with a relative density of 1.30-1.35 (60℃); Step S12, granulation, the torch flower root extract and starch are mixed to obtain wet granules, and the ratio of the torch flower root extract to starch is 10-20:1; Step S13, drying and sizing, the wet granules are sequentially subjected to drying, cooling, discharging and sizing to obtain dry granules; Step S14, mixing, the sieved talc and magnesium stearate are added to the dry granules, and after uniform mixing, total mixed granules are obtained, and the content is determined, and the ratio of the dry granules to talc and magnesium stearate is 300-600:2:1; Step S15, tabletting, the total mixed granules are compressed into tablet cores, and the torch flower root tablet tablet cores are obtained.
[0040] Step S2, preparation of torch flower root tablet film coating liquid, the colorant, talc, hydroxypropyl methyl cellulose, colloidal microcrystalline cellulose and polypropylene glycol are added to purified water, uniformly mixed and filtered to obtain the coating liquid, and according to the amount, the colorant, talc, hydroxypropyl methyl cellulose, colloidal microcrystalline cellulose and polypropylene glycol account for 1-4:4-6:10-20:1-2:2-3, respectively, and the overall solution concentration is 20%-25%.
[0041] Step S3, using the coating pan 2 in the above production device to dry and preheat the torch flower root tablet tablet cores, and using the air blower to suck out the drug fine powder from the ventilation groove, specifically as follows: Step S31, the torch flower root tablet tablet cores are put into the coating pan 2, the linear driving part 10 pushes the sliding frame 13 to make all the sliding bars 19 inserted into the discharging groove, the sealing plate 14 blocks the discharging port, and the baffle 16 opens the ventilation port; Step S32, the driving mechanism is started to make the coating pan 2 rotate, and at the same time, hot air is sent into the hot air pipeline to preheat and dry the tablet cores, and the hot air temperature is 50-70℃, and the time is 5-10 min; at the same time, the air blower is started, and the dust generated in the coating pan 2 is sucked into the air bellow 6 through the first gap and the second gap under the action of negative pressure, and finally collected into the external dust collection bag by the air blower.
[0042] Step S4, after drying, the prepared torch flower root tablet film coating liquid is uniformly sprayed onto the preheated torch flower root tablet tablet cores through the coating liquid pipeline, so that a film coating layer is formed on the surface of the torch flower root tablet tablet cores, and the torch flower root tablet film coated tablets are obtained. During this process, the air blower continuously works to adsorb newly generated dust.
[0043] Step S5, discharging, closing the hot air fan and liquid pump, while the linear drive 10 pushes the sliding frame 13 to make all the sliding bars 19 slide out of the discharging chute, the sealing plate 14 opens the discharging port, and the inclined sealing plate 14 can also guide the falling finished torch flower root film-coated tablet to prevent the finished torch flower root film-coated tablet from accumulating, and the baffle 16 blocks the ventilation port, and the finished torch flower root film-coated tablet is guided out from the discharging box 7 and the chute 8.
[0044] The method can realize real-time suction of the drug fine powder from the ventilation groove through the air suction of the air blower during the drying and preheating of the torch flower root tablet core in the coating pan 2. Firstly, the drug dust is no longer accumulated in the coating pan 2 and the spray gun, which greatly reduces the cleaning work intensity after each batch of production, saves the labor and time cost, reduces the equipment wear and tear, and reduces the long-period maintenance frequency and cost of the equipment. Secondly, the quality problems such as pitting, blistering or peeling caused by the dust embedded in the film are effectively prevented, the defective rate and rework rate are reduced, and the finished product rate and the output of high-quality products in the production process are improved. Thirdly, the collected dust is relatively pure drug raw materials, which makes it easier and more economical to recycle or conduct centralized and compliant environmental protection treatment, thereby reducing the waste disposal burden and cost. It can be seen that the device has positive technical progress in multiple dimensions such as quality, cost, efficiency, environmental protection and safety, and provides strong technical support for the modern production of the torch flower root film-coated tablet.
[0045] The above is only a preferred embodiment of the present application, and does not limit the present application in any form. Although the present application has been disclosed as above with a preferred embodiment, it is not intended to limit the present application. Any person skilled in the art can make some changes or modifications to the above disclosed technical content to obtain equivalent embodiments with equivalent changes, without departing from the technical solution of the present application. Any indirect modification, equivalent change and modification of the above embodiments based on the technical essence of the present application are still within the scope of the technical solution of the present application.
Claims
1. A device for producing film-coated sheets of Torchflower Root Tablets, characterized in that: It includes a frame, a coating pan tilted on the frame, a drive mechanism for rotating the coating pan, and hot air pipes and coating liquid pipes that extend into the coating pan for supplying hot air and coating liquid respectively. The side wall of the coating pan is provided with ventilation grooves evenly distributed along the rotation axis of the coating pan. The width of the ventilation grooves is less than the thickness of the torch flower core. The frame is provided with a support sleeve covering the ventilation grooves. The outer wall of the coating pan is rotatably connected to the support sleeve. The support sleeve is provided with a bellows communicating with the ventilation grooves. The frame is provided with a blower. The air inlet of the blower is connected to the bellows.
2. The apparatus for producing film-coated sheets of Torchflower Root Tablets according to claim 1, characterized in that, The coating pan includes a first pan body and a second pan body that are rotatably connected to the support sleeve. A groove is formed between the second pan body and the second pan body, and a plurality of connecting lugs are provided between the first pan body and the second pan body. A plurality of fixing strips located in the groove are provided on the top of the bellows. A first gap with a width less than the thickness of the torch flower core is formed between the fixing strips and the first pan body and the second pan body.
3. The apparatus for producing a film-coated sheet of Torchflower Root Tablets according to claim 2, characterized in that, A feeding trough with a width greater than the diameter of the torch flower core is formed between adjacent fixed strips, and sliding strips extending into the feeding trough are slidably connected inside the bellows. A feeding box communicating with the feeding trough is provided at the bottom of the bellows.
4. The apparatus for producing film-coated sheets of Torchflower Root Tablets according to claim 3, characterized in that, A second gap, smaller in width than the thickness of the torch flower core, is formed between the fixed strip and the sliding strip.
5. The apparatus for producing film-coated sheets of Torchflower Root Tablets according to claim 3, characterized in that, The inner wall of the support sleeve is also provided with a sealing strip embedded in the groove, and the two ends of the sealing strip are closed and connected to the two ends of the fixing strip.
6. The apparatus for producing film-coated sheets of Torchflower Root Tablets according to claim 3, characterized in that, It also includes a conversion assembly for driving the sliding bars to slide within the bellows, comprising a linear drive and a sliding frame driven by the linear drive, the sliding frame being connected to each sliding bar respectively.
7. The apparatus for producing film-coated sheets of Torchflower Root Tablets according to claim 6, characterized in that, The bottom of the sliding frame is also provided with a sealing plate that can block the connection between the feeding box and the air box. When the sliding bar extends into the feeding groove, the sealing plate blocks the connection between the feeding box and the air box; when the sliding plate extends out of the feeding groove, the feeding box and the air box are connected.
8. The apparatus for producing film-coated sheets of Torchflower Root Tablets according to claim 6, characterized in that, The sliding frame is equipped with a baffle that can block the connection between the blower and the air box. When the sliding bar extends into the feeding trough, the blower and the air box are connected; when the sliding plate extends out of the feeding trough, the sealing plate blocks the connection between the blower and the air box.
9. A process for producing film-coated tablets of Torchflower root slices, characterized in that, The production process includes using the production apparatus described in any one of claims 1-8 to produce Torchflower Root Tablets with film coating, and the steps are as follows: Step S1: Prepare the root core of Torch Flower; Step S2: Prepare the film coating solution for Torchflower root slices; Step S3: The core of the Torch Flower Root Slices is dried and preheated using the coating pan in any of the production apparatuses described in claims 1-8, and the fine powder of the medicine is drawn out from the ventilation duct by a blower. Step S4: The prepared Torch Flower Root Slice Film Coating Solution is evenly sprayed onto the preheated Torch Flower Root Slice Core through the coating solution pipeline, so that a film coating layer is formed on the surface of the Torch Flower Root Slice Core, thus obtaining the Torch Flower Root Slice Film Coated Slice.
10. The process for producing a film-coated sheet of Torchflower root slices according to claim 9, characterized in that, Step S1 includes the sequential preparation of Torchflower root extract, granulation, drying and granulation, mixing, and tableting. The preparation of Torchflower root extract is as follows: Torchflower roots are taken, cut into thin slices, boiled in water multiple times, the decoctions are combined and filtered, and the filtrate is concentrated to a clear extract with a relative density of 1.05 to 1.07 at 60°C. Ethanol is then added to make the alcohol content of the clear extract reach 70%. After stirring, it is allowed to stand for 12 hours, filtered again, and the ethanol is recovered from the filtrate and concentrated to a thick extract with a relative density of 1.30 to 1.35 at 60°C.