Biological safety system suitable for culture community
By constructing a biosafety system in aquaculture communities, the problems of independent links and static and fixed defense strategies in existing technologies have been solved, achieving dynamic adaptive defense and effective blocking of aerosol transmission, thus improving the level of biosafety control.
Patent Information
- Application Number
- CN202511437005.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-10-09
- Publication Date
- 2026-01-06
AI Technical Summary
Existing biosafety measures are independent of each other and lack coordination. The defense strategies are static and fixed, unable to adaptively adjust the defense level according to real-time risks, and have insufficient defense capabilities against aerosol transmission paths.
Construct a biosecurity system suitable for aquaculture communities, including spatial zoning and hardware facility modules, four-way closed-loop management modules, environmental pressure gradient control modules, and integrated monitoring and protection modules, to achieve dynamic adaptive defense.
A multi-layered, closed-loop integrated biosafety defense system has been established, which can automatically adjust the defense level according to real-time risks, effectively block the transmission path of pathogens via aerosols, and improve the overall prevention and control capabilities.
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Figure CN121279945A_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the technical field of livestock and poultry breeding epidemic prevention, in particular to a biological safety system suitable for breeding plots. BACKGROUND
[0002] African swine fever (ASF) is a viral disease that poses a serious threat to the global pig industry, characterized by extremely high morbidity and mortality. Since there is currently no commercially viable vaccine, establishing and implementing a strict biosecurity system is the only effective means of preventing and controlling the disease.
[0003] To address biosecurity challenges, existing large-scale farms generally adopt a variety of biosecurity measures. These measures typically include the establishment of physical fences, the cleaning and disinfection of incoming vehicles and personnel, and the development of a series of management regulations and systems. These efforts have achieved remarkable results in practice, successfully building the first physical line of defense for farm biosecurity. By strictly cleaning and disinfecting key points, these schemes effectively reduce the probability of pathogens being directly carried into the production core area by high-risk carriers such as personnel and vehicles.
[0004] With in-depth research on the transmission routes of the virus, the inherent defects of existing technologies have gradually been exposed. First, the biosecurity measures in existing technologies are often isolated and superimposed, with vehicle washing, personnel showering, and material disinfection each having its own system, resulting in the overall security of the system relying on the strict execution of each link by people. Once there is negligence at a certain point, the entire defense chain may be broken, as the system itself lacks the ability to automatically compensate or respond in conjunction. Second, another significant limitation of existing biosecurity systems is their static defense strategy. Most farms implement a fixed set of operating procedures, such as when the door of a critical access is abnormally opened, the system cannot automatically raise the security level or link other devices to perform blocking or isolation. In addition, current technical solutions pay excessive attention to the blocking of contact transmission routes, and the existing technology is obviously insufficient in attention and control means for air transmission through aerosols, etc. Although farms generally install ventilation systems, their design goals are mostly to regulate the temperature and humidity in the shed, and few systems consider maintaining a stable pressure gradient between different security level areas as a core operating goal, leaving a critical blind spot in prevention and control. SUMMARY
[0005] In view of the deficiencies of the existing technology, the present application provides a biological safety system suitable for breeding plots, which solves the technical problems of the existing technology that each epidemic prevention link is independent of each other, lacks linkage, and the overall defense strategy is static and fixed, unable to adaptively adjust the defense level according to real-time risks.
[0006] To achieve the above object, the present application is implemented by the following technical solutions: A biological safety system suitable for breeding plots, comprising: A space partition and hardware facility module, configured to divide the breeding plot into physical functional areas and configure hardware facilities, thereby constructing a physical framework; A four-main-line closed-loop management module, configured to establish and execute standard operating procedures for one-way flow of personnel, materials, vehicles and pigs in the physical framework; An environmental pressure gradient regulation module, configured to establish and dynamically maintain a stable air pressure gradient in the physical functional areas, which makes air flow from high biological safety level areas to low biological safety level areas; An integrated monitoring and protection module, configured to collect and output real-time state data through a sensor network, the real-time state data including actual pressure difference values for the environmental pressure gradient regulation module, and trigger conditions for logical judgment; A biological safety state interlocking control module, configured to receive the trigger conditions, and automatically generate and issue interlocking control instructions to the hardware facilities and target pressure difference value instructions to the environmental pressure gradient regulation module according to preset system state and interlocking control strategies.
[0007] In a specific embodiment, the space partition and hardware facility module includes a space partition system and a hardware facility system.
[0008] The space partition system physically divides the breeding plot into five functional areas, including an external service area, a living area, a production area, a pig delivery area and an environmental protection area, through physical walls and internal road planning.
[0009] The hardware facility system includes a vehicle decontamination and drying center and a material disinfection warehouse in the external service area, a three-section dressing and shower room for personnel decontamination at the boundary between the living area and the production area, a pig delivery room in the pig delivery area, and a dead pig harmless treatment channel connecting the production area and the environmental protection area.
[0010] In a specific embodiment, the standard operating procedures executed by the four-main-line closed-loop management module include control processes for four core flow elements of personnel, materials, vehicles and pigs.
[0011] The personnel flow control process requires personnel to pass through the three-section dressing and shower room to complete the sequence of undressing, showering and wearing clean clothes when crossing different biological safety level areas.
[0012] The material flow control process stipulates that all external materials must be classified and disinfected in the material disinfection warehouse before being transferred to the clean area warehouse through the delivery window.
[0013] The vehicle movement control process stipulates that all off-site vehicles must complete the cleaning, disinfection, and drying processes and meet the core parameters before they can enter the designated work area.
[0014] The pig movement control process utilizes a pig transfer channel that physically separates the off-site area from the on-site area to achieve the transfer of pigs.
[0015] In one specific embodiment, the environmental pressure gradient control module maintains the stable air pressure gradient through a closed-loop feedback control mechanism.
[0016] The closed-loop feedback control mechanism includes the following steps: First, the actual pressure difference between adjacent areas is monitored and obtained in real time using a differential pressure sensor; Subsequently, the actual differential pressure value is compared with the preset target differential pressure value to calculate the differential pressure error; Next, the total control output signal is calculated based on the differential pressure error using a proportional, integral, and derivative control model. Finally, the overall control output signal is converted into adjustment commands for the central fresh air unit and exhaust fan unit, driving the fan unit to adjust the air supply or exhaust volume so that the actual pressure difference value approaches and stabilizes within the range of the target pressure difference value.
[0017] In one specific embodiment, the operating mechanism of the biosafety status interlocking control module includes a system state definition and automatic migration model and a cross-module parameter interlocking control strategy.
[0018] The system state definition and automatic migration model predefines a finite set of global biosafety response levels, including normal state, early warning state, and lockdown state, and drives the system to automatically migrate between different states in the finite set of states through a state migration function based on the received trigger conditions.
[0019] The cross-module parameter interlocking control strategy maps the current state of the system to a set of specific hardware unit operating parameter settings through an interlocking control strategy function, and automatically sends the set of settings to the corresponding hardware execution unit.
[0020] In one specific embodiment, the integrated monitoring and protection module includes a multi-dimensional data acquisition and fusion system, a system status visualization and decision support system, and a basic environmental protection system.
[0021] The multidimensional data acquisition and fusion system includes a video surveillance network and an Internet of Things (IoT) sensor network, used to acquire and fuse video stream data, behavioral event data, and real-time data from various sensors.
[0022] The system situation visualization and decision support system is used to present the current global biosafety status of the system, as determined by the biosafety status interlocking control module, and the operating status of each hardware facility to the management personnel in a graphical manner.
[0023] The basic environmental protection system includes a water treatment unit that physically filters, chlorinates, and inactivates all incoming water sources into the site.
[0024] Preferably, in the vehicle movement control process, the core parameters of the drying process are limited to: After the hot air circulation system is started, the temperature sensor reading inside the carriage must reach 60 degrees Celsius and maintain that temperature for at least 45 minutes from the moment it is reached.
[0025] Preferably, in the proportional, integral, and derivative control model, the calculation method of the total control output signal is limited to: The total control output signal is obtained by weighted summing of the proportional term of the differential pressure error, the time integral term of the differential pressure error, and the time derivative term of the differential pressure error. The proportional term is used to determine the response strength to the current error, the integral term is used to eliminate the steady-state error of the system, and the derivative term is used to suppress system overshoot and oscillation.
[0026] Preferably, the operation mechanism of the biosafety status interlocking control module further includes an immediate response mechanism for critical process failures. The immediate response mechanism is used for: When a predefined critical process failure event is detected, instead of performing a global system state transition, a set of device locking actions strongly related to the failure event are executed directly and quickly through an immediate action function.
[0027] Preferably, the IoT sensor network includes: A high-precision differential pressure sensor installed on the partition wall of the area to collect the actual differential pressure value; Temperature sensors and timers installed in the vehicle washing, disinfection and drying center are used to determine whether the core parameters of the disinfection process meet the standards. Door magnetic sensors and access control card readers installed on key access doors are used to monitor access status and personnel access permissions.
[0028] This invention provides a biosecurity system suitable for aquaculture communities. It has the following beneficial effects: 1. This invention systematically integrates spatial zoning, hardware facilities, traffic flow, environmental control and intelligent interlocking management to construct a multi-level, closed-loop comprehensive biosafety defense system. Compared with the existing technology where each epidemic prevention link is independent and lacks overall planning, this invention solves the systemic prevention and control loopholes.
[0029] 2. This invention sets up a biosafety status interlocking control module, which defines the defense level as a system state that can automatically migrate according to real-time risks, and adjusts the operating parameters of hardware facilities and environmental control targets in a coordinated manner. This realizes the transformation from static fixed defense to dynamic adaptive defense. Compared with the technical solutions of the prior art that adopt fixed biosafety measures, it solves the fundamental defect that the defense level does not match the actual risk.
[0030] 3. This invention adds an active aerodynamic barrier outside the physical barrier through an environmental pressure gradient control module. It adopts PID closed-loop feedback control to ensure the continuous stability of the barrier and effectively block the aerosol transmission path of pathogens. Compared with the existing technology that mainly relies on physical walls for physical isolation, this invention solves the problem of insufficient defense against invisible risk sources such as aerosols. Attached Figure Description
[0031] Figure 1 This is a schematic diagram of the overall system framework of an embodiment of the present invention; Figure 2 This is a schematic diagram of the spatial partitioning and hardware facility modules according to an embodiment of the present invention; Figure 3 This is a schematic diagram illustrating the working principle of the environmental pressure gradient control module according to an embodiment of the present invention. Figure 4 This is a logic control block diagram of the biosafety status interlocking management module according to an embodiment of the present invention; Figure 5 This is a schematic diagram of the data flow of the integrated monitoring and protection module in an embodiment of the present invention.
[0032] Among them, 10. Spatial zoning and hardware facilities module; 20. Four major circulation closed-loop management module; 30. Environmental pressure gradient control module; 40. Biosafety status interlock control module; 50. Integrated monitoring and protection module. Detailed Implementation
[0033] The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.
[0034] See attached document Figure 1 , attached Figure 1 This is a schematic diagram of the overall framework of a biosafety system suitable for aquaculture communities according to an embodiment of the present invention. The biosafety system for aquaculture communities provided by the present invention may include: a spatial zoning and hardware facility module 10, a four-path closed-loop management module 20, an environmental pressure gradient control module 30, a biosafety status interlocking control module 40, and an integrated monitoring and protection module 50.
[0035] The system is built upon the fundamental biosafety principles of clean and contaminated area separation, unidirectional flow, effective disinfection, and controlled zones. Building upon this foundation, the system further integrates a dynamic control mechanism, combining static physical barriers and process management with dynamic environmental control and intelligent interlocking to form a comprehensive defense system capable of adaptively adjusting to real-time risks.
[0036] The spatial zoning and hardware facility module 10 is used to physically divide the breeding area into functional zones and configure the hardware facilities required to implement biosecurity measures. The spatial zoning and hardware facility module 10 is the physical foundation and carrier for the operation of the entire system.
[0037] The Four-Way Closed-Loop Management Module 20 is used to establish and execute standard operating procedures for the four types of movement elements: personnel, materials, vehicles, and pigs. The Four-Way Closed-Loop Management Module 20 ensures that all movement elements follow strict principles of unidirectional movement, cleanliness, and isolation within the physical framework constructed by the spatial zoning and hardware facility module 10.
[0038] The environmental pressure gradient control module 30 is used to establish and dynamically maintain a stable air pressure gradient between areas with different biosafety levels through HVAC technology. In addition to physical isolation, the environmental pressure gradient control module 30 adds an extra aerodynamic barrier for active defense against aerosol propagation.
[0039] The biosafety status interlock control module 40 is the central logic control unit of the system. Based on preset biosafety response levels and real-time monitoring of internal and external risk events, the biosafety status interlock control module 40 automatically adjusts and enforces the operating parameters and access permissions of associated hardware facilities.
[0040] The integrated monitoring and support module 50 provides real-time status data input to the environmental pressure gradient control module 30 and the biosafety status interlocking control module 40 through a video monitoring system and various sensor networks. Simultaneously, the integrated monitoring and support module 50 also provides a visual interface for system status to management personnel and is responsible for the operation of basic support systems such as water treatment.
[0041] In one embodiment of the present invention, the spatial partitioning and hardware facility module 10, the four major circulation loop closed-loop management module 20, the environmental pressure gradient control module 30, the biosafety status interlocking control module 40, and the integrated monitoring and protection module 50 cooperate with each other. The data collected by the integrated monitoring and protection module 50 drives the biosafety status interlocking control module 40 to perform logical judgments and decisions. The decision results then instruct the environmental pressure gradient control module 30 and other hardware facilities to adjust their operating status, thereby achieving adaptive adjustment of the defense strength of the entire biosafety system on top of the standard procedures specified by the four major circulation loop closed-loop management module 20.
[0042] Before providing a detailed description of the system of the present invention, it is important to understand that the system implements its functions in a modular manner. The following will describe each module constituting the system in detail to disclose its specific implementation and working principle.
[0043] See attached document Figure 2 , attached Figure 2 This is a schematic diagram of the spatial partitioning and hardware facility module 10 according to an embodiment of the present invention. The biosafety system for aquaculture communities provided by the present invention uses the spatial partitioning and hardware facility module 10 as the physical basis for the operation of the entire system, serving as a key hardware carrier for constructing functionally defined physical barriers and implementing biosafety measures.
[0044] The spatial zoning and hardware facility module 10 includes a spatial zoning system and a hardware facility system. The spatial zoning system physically divides the breeding area into functionally independent zones with different biosecurity levels through physical walls, internal road planning, and green isolation belts. These zones include: the field work zone (OSZ), the living zone (LQZ), the production zone (PZ), the pig output zone (SDZ), and the environmental protection zone (EPZ).
[0045] The Outdoor Working Zone (OSZ) is defined as a Level 1 contaminated zone. It is the primary interface between the breeding area and the external environment. It is used for preliminary and mandatory disinfection and purification of all personnel, vehicles and materials entering the area, and is the first line of defense against the introduction of external pathogens.
[0046] The Living Area (LQZ) is defined as a buffer zone, physically located between the Operating Area (OSZ) and the Production Area (PZ). The Living Area (LQZ) is the place where on-site management and production personnel conduct their daily lives and work. Its core function is to serve as a transitional area for personnel to undergo final purification and changing clothes before entering the core Production Area (PZ), thereby achieving physical and process isolation between the living environment and the production environment.
[0047] The Production Zone (PZ) is defined as a clean zone and is the highest level of protection area in the entire biosecurity system. The Production Zone (PZ) is physically and strictly isolated from all other areas, and is connected to the Living Zone (LQZ) only through function-specific hardware facilities (such as the main changing room and material transfer channels) in a controlled manner. It is used for the feeding and growth of pigs. In addition, the Production Zone (PZ) can be further divided into several independent breeding units, such as nursery units and finishing units, according to the feeding plan, to meet the needs of refined management and disease zoning prevention and control for pigs of different ages.
[0048] The sludge delivery zone (SDZ) is defined as a secondary contaminated area, located downwind of the production zone (PZ), and has its own independent off-site connection. The SDZ is dedicated to the transfer of market-ready pigs, and its independent design ensures that vehicles and personnel involved in the pig selling process do not pose a biosecurity risk to the production zone (PZ).
[0049] The Environmental Protection Zone (EPZ) is defined as an independent waste area. In terms of site selection, it is independently located downwind of the Production Zone (PZ) in the prevailing wind direction and completely isolated from the Production Zone by a solid wall. The EPZ is used for centralized treatment of manure and waste from dead pigs within the plant area. Its connection to the Production Zone (PZ) is achieved through a specific one-way waste transfer channel, ensuring that pollutants do not flow back into the Production Zone (PZ).
[0050] Based on the above spatial zoning system, the hardware infrastructure is configured specifically within each zone, and its implementation includes: 1. Vehicle Washing, Disinfection and Drying Center: Located in the Outdoor Service Zone (OSZ), this center processes all external vehicles entering the area. It consists of a washing and disinfection workshop and a drying workshop connected in series, ensuring unidirectional vehicle flow. The washing and disinfection workshop is equipped with a high-pressure washing system, a foam spraying system, and an automatic disinfectant dispensing system. The drying workshop is a closed structure, equipped with a heat source (such as a fuel-fired hot air furnace or electric heating) and a hot air circulation system. Temperature sensors are installed to monitor and maintain the temperature inside the vehicle compartment to achieve preset disinfection parameters.
[0051] 2. Three-section changing and shower room: As a key control hardware in personnel passage, it is located at the boundary between the living area (LQZ) and the production area (PZ) (serving as the main changing room), and at the entrance of each pig house within the production area (PZ) (serving as part of the production support room). Internally, it is divided by solid walls into three continuous and unidirectionally connected compartments: a soiled laundry room (section 1), a shower room (section 2), and a clean laundry room (section 3). This structure mandates that personnel must pass through in the order of undressing-showering-putting on clean clothing, physically eliminating the possibility of bypassing the shower step.
[0052] 3. Material Disinfection Warehouse: Located in the Operating Area (OSZ), this warehouse is used for the disinfection of all incoming materials. Internally, it is divided into three unidirectionally connected areas by solid walls: the contaminated area warehouse, the processing area, and the clean area warehouse. The processing area is equipped with different disinfection facilities based on the physicochemical properties of different materials. These include: immersion pools for disinfecting corrosion-resistant instruments or items; high-temperature drying rooms for disinfecting heat-resistant items (such as clothing and tools); and workbenches for wiping or fumigating non-heat- and moisture-sensitive electronic products. Disinfected materials are transferred unidirectionally between the processing area and the clean area warehouse via a pass-through window.
[0053] 4. Pig Entry and Exit Areas: The pig entry area is located in the Outdoor Working Zone (OSZ), and the pig exit area is located in the Exit Zone (SDZ). Both are enclosed buildings internally divided into an off-site area (dirty side) and an on-site area (clean side). The off-site and on-site areas are connected by a V-shaped or similar herding tunnel. This design allows off-site transport vehicles to park in the off-site area, and on-site transfer vehicles to park in the on-site area, with pigs being transferred within the tunnel, thus achieving complete physical isolation of vehicles and personnel between the on-site and off-site areas.
[0054] 5. Dead Pig Disposal Channel: Located on the isolation wall between the Production Zone (PZ) and the Environmental Protection Zone (EPZ). The channel is essentially a platform for dead pigs to fall through. The platform has an opening in the wall on the Production Zone (PZ) side, while its exit is located on the Environmental Protection Zone (EPZ) side. The exit is at least 0.5 meters above the ground in the Environmental Protection Zone to prevent backflow of contaminants. A dedicated staff passage and separate shower and changing rooms are provided for the Environmental Protection Zone to ensure that personnel entering and leaving the zone do not pose a risk of cross-contamination to other areas. Workers in the Production Zone (PZ) can directly drop dead pigs through this channel, allowing them to slide down to a designated collection point in the Environmental Protection Zone (EPZ) by gravity, achieving one-way, cross-contamination of waste.
[0055] The Four Major Movement Flow Closed-Loop Management Module 20, based on the physical framework built by the spatial zoning and hardware facility module 10, is used to define and execute standard operating procedures for four core movement elements: personnel, materials, vehicles, and pigs. The core function of the Four Major Movement Flow Closed-Loop Management Module 20 is to ensure that the movement of all elements within the breeding area strictly adheres to the principles of unidirectional, clean, and isolated movement from low-biosecurity-level areas to high-biosecurity-level areas, thereby constructing a closed-loop process barrier.
[0056] The four major flow closed-loop management module 20 specifically controls the four major flow elements through the following processes: 1. Personnel movement control process: The system mandates the movement paths of all personnel, especially when crossing the boundaries of areas with different biosafety levels, and adopts a multi-level health passage system.
[0057] Specifically, this is implemented as follows: any personnel entering the production area (PZ) from the living area (LQZ) must, and can only, pass through the main changing room located at the boundary between the two areas. Within this main changing room, personnel must sequentially pass through three physically separated functional rooms to complete a three-stage changing and showering process. All three-stage changing and showering rooms are equipped with air conditioning and a 24-hour hot water system to ensure that personnel strictly adhere to the showering procedures regardless of the season.
[0058] The three-stage changing and showering process includes: removing all clothing from the living area (LQZ) in the soiled clothing room in the first zone; taking a full-body shower in the shower room in the second zone for the prescribed time; and putting on clean work clothes and boots specifically for the production area (PZ) in the clean clothing room in the third zone. Similarly, within the production area (PZ), before entering any independent pigsty from the farm roads, personnel must undergo another independent three-stage changing and showering process in the production support room at the pigsty entrance. In addition, this production support room is equipped with small disinfection soaking tanks and small drying cabinets for handling small, loose items, serving as a final disinfection barrier before materials enter the pigsty. This process design physically eliminates the possibility of personnel carrying pathogens across zones.
[0059] 2. Material Movement Control Process: The system stipulates that all incoming materials must be processed through the material disinfection warehouse located in the field service area (OSZ). After entering the warehouse, materials are first stored in the contaminated area warehouse, and then classified and disinfected in the processing area according to their physical and chemical properties.
[0060] The specific disinfection methods for this category include: For corrosion-resistant metal instruments or plastic products, the treatment method is to soak them in a disinfectant soaking tank with a potassium persulfate compound solution at a concentration of 1:200 at room temperature (e.g., 25°C) for no less than 1 hour. For heat-resistant clothing, tools, etc., the method of drying in a high-temperature drying room at a temperature set at 65℃ for no less than 1 hour is adopted. For electronic devices, vaccines, medicines, or paper documents that are not resistant to humidity and heat, they should be repeatedly wiped and disinfected with 75% alcohol on a dedicated workbench, and then transferred to a separate drying room with the temperature maintained at 40°C and left to stand for 7 days.
[0061] After all materials complete the disinfection process in the processing area, they are transferred unidirectionally through a pass-through window between the processing area and the clean zone warehouse. Materials in the clean zone warehouse are retrieved and distributed by dedicated transport vehicles within the production zone (PZ), achieving complete purification and isolation of external materials from entry to the production environment.
[0062] 3. Vehicle Movement Control Process: The system implements strict physical isolation and process control between off-site and on-site vehicles. All off-site vehicles entering the Operating Area (OSZ), such as feed transport vehicles, must complete a standardized processing procedure at the vehicle washing, disinfection and drying center.
[0063] The process includes the following sequential steps: First, the vehicle enters the cleaning and disinfection workshop, where a high-pressure hot water washing machine with a working pressure maintained at 100-150 Bar thoroughly removes organic pollutants from the vehicle body, especially the chassis and tires. Secondly, the foam spraying system evenly covers all the outer surfaces of the vehicle with a glutaraldehyde-decylmethylammonium bromide solution diluted at a ratio of 1:200 in the form of foam, and ensures the specified effective action time. Next, after rinsing off the foam and disinfectant residue with high-pressure water, spray the entire vehicle body with a 1:300 diluted potassium persulfate compound solution for terminal disinfection. Finally, the vehicle enters the enclosed drying workshop. In one specific embodiment, the hot air circulation system of the drying workshop is activated, with a target temperature set at 65°C. The temperature sensors installed inside the vehicle are required to maintain a reading above 60°C for at least 45 minutes. During this process, the driver's cab door must remain open, and an independent temperature recorder must be placed inside to ensure that the cab also meets disinfection standards. Only after completing the entire process and meeting all parameters are the vehicle authorized to proceed to the designated work point, such as below the centralized material tower. Throughout this process, vehicles from outside the site are strictly prohibited from entering the living quarters (LQZ) and production areas (PZ). Feed and other supplies are transported to the production area (PZ) via pipelines or other transfer methods to prevent direct vehicle entry.
[0064] 4. Pig movement control process: The system utilizes pig entry pens located in the operating area (OSZ) and pig exit pens located in the exit area (SDZ) to implement biosecurity isolation for the introduction and transfer of pigs. Whether pigs are entering or leaving, the handover process is completed within a dedicated pig handover channel.
[0065] The structural design of this pig transfer channel physically separates the dirty side area where off-site transport vehicles park from the clean side area where on-site transfer vehicles park. As pigs are driven through this enclosed channel, they complete the transfer from one transport system to another. This design ensures that off-site transport vehicles, drivers, and the surrounding environment do not have any direct or indirect contact with on-site transport systems and personnel, thus closing off the risk pathways for the introduction or transmission of pathogens through pig movement.
[0066] See attached document Figure 3 , attached Figure 3 This is a schematic diagram illustrating the working principle of an environmental pressure gradient control module 30 according to an embodiment of the present invention. The function of the environmental pressure gradient control module 30 is to add an aerodynamic barrier for actively defending against the spread of pathogen aerosols, based on the physical barrier constructed by the spatial partitioning and hardware facility module 10.
[0067] The environmental pressure gradient control module 30 establishes and dynamically maintains a stable and orderly air pressure gradient between areas with different biosecurity levels within the aquaculture area through a central fresh air and exhaust system. This pressure gradient is designed to ensure that the macroscopic airflow always flows from areas with high biosecurity levels to areas with low biosecurity levels. In a specific embodiment, the target relationship of this pressure gradient is set as follows:
[0068] in: The average static air pressure representing the production zone (PZ); The average static air pressure representing the living area (LQZ); The average static air pressure representing the field zone (OSZ); This represents the atmospheric pressure outside the breeding area.
[0069] To achieve and maintain the aforementioned pressure gradient, the environmental pressure gradient control module 30 employs a closed-loop feedback control mechanism. The hardware foundation of this closed-loop feedback control mechanism includes: high-airtightness doors deployed at the boundaries of each area, high-precision differential pressure sensors installed on the partition walls of each area, and central fresh air units and exhaust air units controlled by frequency converters.
[0070] During system operation, the differential pressure sensor monitors and reports the actual pressure difference between adjacent areas in real time. Based on this feedback value, the controller within the environmental pressure gradient control module 30 dynamically adjusts the power of the supply and exhaust fans to maintain a stable pressure difference. This dynamic maintenance process is achieved through a proportional-integral-derivative (PID) control model.
[0071] The control model for the pressure difference at the boundary between any two adjacent regions is as follows: 1. First, define the system at time... Pressure difference error :
[0072] in: This is the preset target pressure difference value at the boundary; It is the actual differential pressure value monitored by the differential pressure sensor at all times.
[0073] Subsequently, the PID controller adjusts the differential pressure error. Calculate at time Total control output signal :
[0074] in: It is the proportional gain coefficient, used to determine the strength of the controller's response to the current error; It is the integral gain coefficient, used to accumulate historical errors to eliminate the steady-state error of the system; It is the differential gain coefficient, used to predict the trend of error changes in order to suppress system overshoot and oscillation.
[0075] Finally, the controller's output signal It is converted into frequency regulation commands for the frequency converter of the blower or exhaust fan. This command drives the fan to adjust its speed, thereby changing the supply or exhaust air volume and thus the actual pressure difference. Approaching and stabilizing at the target pressure difference Within a certain range. This closed-loop control process continues to cope with pressure fluctuations caused by factors such as door opening and closing, personnel movement, and changes in external wind pressure, ensuring the continuous effectiveness of the aerodynamic barrier.
[0076] See attached document Figure 4 , attached Figure 4 This is a logic control block diagram of the biosafety status interlocking control module 40 according to an embodiment of the present invention. The biosafety status interlocking control module 40 is the central logic control unit of the entire biosafety system. Its function is to integrate data information from various sources, determine the risk level, and automatically and forcibly adjust the operating parameters and permissions of each associated hardware facility in the system according to the determination result, so as to realize the adaptive adjustment of the defense strength of the entire system.
[0077] The biosafety status interlock control module 40 implements its functions through the following mechanisms: 1. System state definition and automatic migration model: The system predefines a finite set S of global biosafety response levels, which includes at least: : Normal state, corresponding to the standard biosecurity defense level during normal production and operation of the breeding community.
[0078] : Warning status, corresponding to the enhanced defense level that the system raises when there is a potential biosafety risk.
[0079] : Lockdown status, the highest level of defense the system adopts when there is a serious or immediate biosecurity threat.
[0080] The system's state transitions are triggered by a pre-defined set of conditions. Driver. This set of triggering conditions. The elements in the data come from multiple sources, including: sensor data collected by the integrated monitoring and assurance module 50 (e.g., vehicle drying temperature not meeting standards, persistent imbalance of regional pressure differential); process event data (e.g., unauthorized access attempts at key access points, personnel staying too short in the shower room); and external information input by authorized administrators (e.g., official alerts of outbreaks in the surrounding area).
[0081] The state transition process is handled by a state transition function. It is described and defined as follows:
[0082] This function represents the state when the system is in a certain condition. At that time, if a triggering condition Once the condition is met, the system will automatically migrate to the new state. .
[0083] 2. Cross-module parameter interlocking control strategy: All hardware units within the system whose parameters can be adjusted by the central controller constitute a parameter set. The elements may include the target temperature and duration of the vehicle drying center, the forced shower time of the three-stage changing and shower room, the access permission list of the personnel access control system, and the target pressure difference value of the environmental pressure gradient control module 30.
[0084] The biosafety status interlocking control module 40 uses an interlocking control strategy function. The current system state Mapped to a specific set of parameter settings The function is defined as follows: ; When the system state transitions, for example from a normal state... Move to early warning status The function The system will output a set of enhanced parameter values, such as: vehicle drying target temperature = 68℃, forced shower duration = standard value × 1.2, non-core personnel access control permission = disabled, and target differential pressure value = standard value + 2Pa. The biosafety status interlock control module 40 will automatically send this set of new parameter settings to the corresponding hardware execution unit, forcing it to operate according to the new parameters.
[0085] 3. Immediate response mechanism for critical process failures: To address localized risk events that do not require raising the overall system state but necessitate rapid intervention, the system also employs an immediate response mechanism. This mechanism targets a predefined set of critical process failure events. ,For example This indicates a failure in the vehicle drying process.
[0086] For any failure event When this occurs, the system will trigger an immediate action function. This function will directly and quickly execute a set of predefined device locking actions that are strongly related to the event. The function is defined as follows: ; Vehicle drying failure incident For example, the trigger condition for this event is that the temperature sensor or timer in the drying room fails to reach the preset standard at the end of the process. Once triggered, The output is a set of action commands: {lock the outlet gate of the drying room, lock the discharge port of the centralized material tower to which the vehicle is scheduled to dock}. This response mechanism bypasses the global state judgment and transition process, ensuring the fastest and most direct blocking of risks at critical nodes.
[0087] See attached document Figure 5 , attached Figure 5 This is a data flow diagram of the integrated monitoring and protection module 50 according to an embodiment of the present invention. The integrated monitoring and protection module 50 is the basic data and environmental support layer of the entire biosafety system. Its function is to provide real-time and accurate data input to the environmental pressure gradient control module 30 and the biosafety status interlock control module 40, and to provide basic environmental protection for the stable operation of the entire system.
[0088] The integrated monitoring and protection module 50 achieves its functions in the following ways: 1. Multidimensional data acquisition and fusion system: This multi-dimensional data acquisition and fusion system is used to collect multi-dimensional status information from various key nodes in aquaculture communities. Specifically, the system includes a video surveillance network and an Internet of Things (IoT) sensor network.
[0089] High-definition cameras are deployed in key locations of the video surveillance network, such as the site gate, vehicle washing and drying center, entrances and exits of the three-section changing and shower rooms, and material disinfection warehouse pass-through windows. This video surveillance network is not only used for recording video footage and post-event tracing, but its video stream data can also be connected to the image analysis unit to identify behavioral events such as area intrusion and abnormal personnel lingering, and these events are used as trigger conditions to output to the biosafety status interlocking control module 40.
[0090] An Internet of Things (IoT) sensor network consists of various sensors deployed within different hardware facilities. Specifically, these include: Installed on the partition wall of the zone, used to collect actual pressure difference values. The high-precision differential pressure sensor's data serves as the real-time feedback input for the closed-loop control of the environmental pressure gradient regulation module 30. Temperature sensors and timers installed in the high-temperature drying room of the vehicle washing and drying center and the material disinfection warehouse are used to determine whether the core parameters of the disinfection process meet the standards. Door magnetic sensors and access control card readers installed on key access doors are used to monitor access status and personnel access permissions. The data collected by all these sensors together constitute the set of trigger conditions for the biosafety status interlocking control module 40 to perform status judgments and transitions. Real-time data source.
[0091] 2. System Situation Visualization and Decision Support System: The situational awareness and decision support system is a human-computer interface located in the central control room. Its function is to present the abstract biosecurity status of the entire aquaculture area to management personnel in an intuitive graphical format, thereby achieving comprehensive situational awareness. In a specific embodiment, this human-computer interface is an electronic sand table or GIS map, on which the following information is overlaid in real time: Real-time pressure values for each area, fed back by differential pressure sensors; Operating status (standby, running, fault) of key hardware facilities (such as decontamination center, hot air furnace); The current status of all controlled access points (open, closed, locked); The current global biosafety status of the system, as determined by the biosafety status interlocking control module 40 (e.g., highlighted in green, yellow, and red, corresponding to the normal status, respectively). Warning status Lockdown When any abnormal event or state transition occurs, the system will display an alarm message on this interface and log it, providing support for management personnel's decision-making and intervention.
[0092] 3. Basic Environmental Support System: This basic environmental protection system ensures the biosecurity of fundamental environmental elements within the aquaculture area, providing underlying support for the effectiveness of all biosecurity measures. A core component of this system is the water treatment unit. This unit performs multi-stage treatment on all incoming water entering the area, with the specific process including: First, physical filtration is performed using quartz sand and activated carbon filters to remove suspended solids and impurities. It then enters the automatic dosing system, where chlorine is added for disinfection at a preset concentration, and the disinfection effect is ensured by an online residual chlorine monitor. Finally, the treated water undergoes a final inactivation process by passing through an ultraviolet sterilizer before entering the water supply network of the living area (LQZ) and the production area (PZ).
[0093] This water treatment unit ensures that all water sources used for personnel showering, equipment cleaning, and pig drinking within the farm are biosafe, thereby eliminating the risk of water as a pathogen transmission medium.
[0094] To further illustrate the collaborative working process of the technical solution of this invention, a specific working scenario example will be used below.
[0095] This embodiment uses a fattening pig breeding community with a designed capacity of 28,800 heads as the application object. This community has fully deployed the biosafety system of this invention, including a spatial zoning and hardware facility module 10, a four-way closed-loop management module 20, an environmental pressure gradient control module 30, a biosafety status interlocking control module 40, and an integrated monitoring and protection module 50. In the initial state, the entire system operates in the normal state defined by the biosafety status interlocking control module 40. .
[0096] On a typical workday, an external feed delivery truck needs to enter the field service area (OSZ) of the livestock farm to replenish the centralized feed tower. This process fully demonstrates the collaborative workflow of the system under normal conditions: 1. After the vehicle arrives at the entrance of the breeding community, it enters the vehicle washing, disinfection and drying center located in the field service area (OSZ) according to the regulations of the four major closed-loop management module 20.
[0097] 2. Inside the disinfection workshop, the vehicles sequentially undergo high-pressure washing, foam disinfectant spraying, and rinsing with clean water. Afterward, the vehicles enter the enclosed drying workshop.
[0098] 3. During this period, the environmental pressure gradient control module 30 continues to operate, maintaining a stable pressure gradient relationship between the production area (PZ), living area (LQZ), and field service area (OSZ) by adjusting the supply and exhaust ventilation systems. This ensures that the air barrier from the inside out remains effective at all times.
[0099] 4. The hot air system in the drying workshop is activated, and the temperature sensor and timer in the integrated monitoring and protection module 50 begin monitoring the interior of the drying compartment. Once the temperature reaches the preset standard of 60℃ under normal conditions, the timer starts counting and maintains the time for 45 minutes.
[0100] 5. After the drying process is completed, the integrated monitoring and assurance module 50 sends data showing that the process is complete and the parameters meet the standards to the biosafety status interlock control module 40. After the biosafety status interlock control module 40 verifies the data, it authorizes the opening of the exit gate of the drying workshop.
[0101] 6. The vehicle drives to the designated centralized material tower and unloads the material through a closed conveying pipeline. Throughout the process, the driver's activity area is strictly limited to the field service area (OSZ), and neither the vehicle nor the personnel enter the living area (LQZ) nor the production area (PZ).
[0102] 7. After unloading, the vehicle leaves the breeding area along the designated route. Throughout the process, the integrated monitoring and support module 50's video surveillance network and visualization interface displays the vehicle's location, washing, disinfection, and drying status, and the feed tower's operation to management personnel in real time.
[0103] To further illustrate the adaptive response capability of the system of the present invention, the system response process under two risk events is described below: Scenario 1: Triggering and responding to failure events in critical internal processes.
[0104] In the aforementioned feed truck drying process, suppose that due to equipment failure, the drying workshop fails to reach the temperature of the truck compartment at 60°C within the specified time.
[0105] 1. When the process ends, the temperature sensor in the integrated monitoring and assurance module 50 will identify any data indicating that the temperature has not met the standard as a critical process failure event. .
[0106] 2. This event directly triggered the immediate action function within the biosafety status interlock control module 40. .
[0107] 3. Real-time action function Immediately execute a set of predefined locking actions, specifically: forcibly lock the exit gate of the vehicle washing, disinfection and drying center to prevent the vehicle from leaving; at the same time, remotely lock the discharge port of the centralized material tower to which the vehicle is scheduled to dock.
[0108] 4. Simultaneously, a clear alarm message pops up on the visualization interface of the integrated monitoring and protection module 50, indicating the failed vehicle, process, and specific cause. This response process does not change the overall state of the system, but achieves rapid and accurate blocking of local risk points.
[0109] Scenario 2: Triggering and responding to external risk information input.
[0110] Suppose that management learns through official channels that a swine epidemic has occurred within a 5-kilometer radius of the breeding area, and manually uses this information as an external trigger. Input system.
[0111] 1. The biosafety status interlock control module 40 receives the trigger condition. Then, its internal state transition function Activated, perform state transition operation This raises the overall biosafety level of the entire system from the normal state. Automatically upgraded to alert status .
[0112] 2. Following this, the interlocking control strategy function of the biosafety status interlocking management module 40... When executed, this function automatically sends a set of enhanced runtime parameters to each associated module: New parameters were issued to the vehicle washing, disinfection and drying center, raising its target drying temperature to 68°C and extending the duration to 60 minutes.
[0113] Instructions were issued to the control units of all three-section changing and shower rooms to extend the mandatory shower time by 20% beyond the standard.
[0114] A new target pressure difference value is sent to the environmental pressure gradient control module 30, increasing the pressure difference setting between each region by 2 Pa to enhance the strength of the aerodynamic barrier.
[0115] Send an instruction to the access control system to temporarily freeze the access rights of all non-core production personnel to enter the production area (PZ).
[0116] 3. After the system completes the parameter switch, all subsequent biosafety operations will automatically proceed according to the warning status. By implementing stricter standards, the entire defense system has achieved adaptive upgrades to adapt to external environmental risks.
[0117] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A biosecurity system suitable for use in a rearing area, characterised in that, The application relates to a biological safety management system for a pig farm, comprising: a space partition and hardware facility module for physically dividing a breeding area into functional areas and configuring hardware facilities to build a physical framework; a four-line closed-loop management module for establishing and executing standard operating procedures for personnel, materials, vehicles and pigs in the physical framework; an environmental pressure gradient regulation module for establishing and dynamically maintaining a stable air pressure gradient in the physical functional areas, which makes air flow from high to low biological safety level areas; an integrated monitoring and guarantee module for collecting and outputting real-time state data through a sensor network, the real-time state data including an actual pressure difference value for the environmental pressure gradient regulation module and a trigger condition for logical judgment; a biological safety state interlocking control module for receiving the trigger condition and automatically generating and issuing interlocking control instructions to the hardware facilities and target pressure difference value instructions to the environmental pressure gradient regulation module according to preset system state and interlocking control strategies.
2. A biosecurity system for use in a rearing area according to claim 1, wherein, The space partition and hardware facility module comprises: a space partition system which physically divides the breeding area into five functional areas, including an external service area, a living area, a production area, a pig delivery area and an environmental protection area; a hardware facility system which comprises a vehicle washing, disinfecting and drying center and a material disinfecting warehouse arranged in the external service area, a three-section dressing and shower room arranged at the boundary between the living area and the production area, a pig delivery room arranged in the pig delivery area and a dead pig harmless treatment channel connecting the production area and the environmental protection area.
3. A biosecurity system for use in a rearing area according to claim 1, wherein, The four-line closed-loop management module comprises: a personnel line control process which requires personnel to pass through the three-section dressing and shower room to complete the sequence of undressing, showering and wearing clean clothes when crossing different biological safety level areas; a material line control process which stipulates that all external materials must be classified and disinfected in the material disinfecting warehouse and then transferred to the clean area warehouse through a delivery window; a vehicle line control process which stipulates that all off-site vehicles must complete the cleaning, disinfecting and drying process and meet the core parameters before entering the designated operation point; a pig line control process which realizes the transfer of pigs by using a pig transfer channel which physically separates the off-site area and the on-site area.
4. The biosecurity system for use in a rearing plot according to claim 1, wherein, The environmental pressure gradient regulation module comprises: a closed-loop feedback control mechanism for maintaining the stable air pressure gradient, which comprises the following steps: real-time monitoring and acquisition of the actual pressure difference value between adjacent areas through a pressure difference sensor; comparing the actual pressure difference value with a preset target pressure difference value to calculate a pressure difference error; calculating a total control output signal according to the pressure difference error through a proportional, integral and differential control model; converting the total control output signal into an adjustment instruction for a central fresh air fan and an exhaust fan set to drive the fan set to adjust the air supply or exhaust amount so that the actual pressure difference value approaches and stabilizes in the range of the target pressure difference value.
5. A biosecurity system for use in a rearing area according to claim 1, wherein, The biosafety state interlocking control module comprises: A system state definition and automatic migration model, which defines a global biosafety response level finite state set including a normal state, a pre-warning state and a blockade state in advance, and automatically migrates the system between different states of the finite state set through a state migration function according to the received trigger condition; A cross-module parameter interlocking control strategy, which maps the current specific state of the system into a set of specific hardware unit operation parameter setting values through an interlocking control strategy function, and automatically issues the setting value set to the corresponding hardware execution unit.
6. A biosecurity system for use in a rearing area according to claim 1, wherein, The integrated monitoring and guarantee module comprises: A multi-dimensional data acquisition and fusion system, which comprises a video monitoring network and an Internet of Things sensor network, for acquiring and fusing video stream data, behavior event data and various types of real-time sensor data; A system situation visualization and decision support system, which presents the current global biosafety state of the system and the operation state of each hardware facility determined by the biosafety state interlocking control module to the management personnel in a graphical manner; A basic environment guarantee system, which comprises a water source processing unit for physically filtering, chlorinating and disinfecting and ultraviolet inactivating all external water sources entering the field area.
7. A biosecurity system for use in a rearing area according to claim 3, wherein, In the vehicle traffic line control process, the core parameters of the drying process are limited as follows: After the hot air circulation system is started, the temperature sensor inside the vehicle compartment must monitor a value of 60 degrees Celsius, and from the time when the temperature is reached, the temperature must be maintained for more than 45 minutes.
8. A biosecurity system for use in a rearing area according to claim 4, wherein, In the proportional, integral and differential control model, the calculation method of the total control output signal is limited as follows: The proportional term of the differential error, the time integral term of the differential error and the time differential term of the differential error are weighted and summed to obtain the total control output signal; Wherein, the proportional term is used to determine the response strength to the current error, the integral term is used to eliminate the steady-state error of the system, and the differential term is used to suppress the overshoot and oscillation of the system.
9. A biosecurity system for use in a rearing area according to claim 5, wherein, The operation mechanism of the biosafety state interlocking control module further comprises an instant response mechanism for key process failure, which is used to: When a pre-defined key process failure event is monitored, the global state of the system is not migrated, but a set of device locking actions strongly related to the failure event are directly and quickly executed through an instant action function.
10. A biosecurity system for use in a rearing area according to claim 6, wherein, The Internet of Things sensor network comprises: A high-precision differential pressure sensor installed on the inter-area partition wall for acquiring the actual differential pressure value; A temperature sensor and a timer installed in the vehicle decontamination and drying center for judging whether the core parameters of the disinfection process meet the standards; A door magnetic sensor and a door access card reader installed on each key passage door for monitoring the passage state and personnel access authority.
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