Traditional Chinese medicine composition for treating skin neoplasm and application

Abstract

The invention relates to the technical field of medicines, in particular to a traditional Chinese medicine composition for treating skin neoplasm and application. The traditional Chinese medicine composition for treating the skin neoplasm is prepared from 0.5 to 2.0 parts of cortex phellodendri, 0.5 to 1.5 parts of gallnut, 0.5 to 2.0 parts of indigo naturalis, 0.05 to 0.25 part of borneol, 0.5 to 1.5 parts of sodium carbonate, 0.2 to 1.2 parts of quick lime, 0.2 to 0.8 part of sodium hydroxide, 0.5 to 1.5 parts of brucea javanica, 0.6 to 1.5 parts of rhizoma pleionis, 1 to 1.5 parts of radix sophorae flavescentis and 0.1 to 0.3 part of calomel. The traditional Chinese medicine composition for treating skin neoplasm provided by the invention has the effects of removing slough and promoting tissue regeneration, and clearing away heat and toxic materials, has good health-care and treatment effects on various skin neoplasm, especially viral skin neoplasm, does not contain any hormone and antibiotic, has no side effects such as allergy and dependence, is suitable for various skin types, and has a good application prospect. And a good treatment effect is achieved.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medicine, in particular to a traditional Chinese medicine composition for treating skin neoplasm and application. BACKGROUND

[0002] Skin neoplasm refers to abnormal proliferative tissue protruding from the normal skin surface, including physiological proliferation such as skin tags and pathological proliferation such as viral warts. The appearance of skin neoplasm may affect the appearance of individuals, especially when they appear on the face or other prominent parts. Due to the change in appearance, patients may feel inferior or uneasy, affecting self-confidence and social activities. In addition, if the skin neoplasm is continuously rubbed or injured, infection may occur, manifested as redness, pain, secretion, etc. Although most skin neoplasm is benign, in rare cases, they may become malignant, endangering the health of patients.

[0003] The formation mechanism of skin neoplasm involves abnormal proliferation of epidermal keratinocytes and degeneration of dermal connective tissue. Currently, skin neoplasm is mainly treated by surgical resection, cryotherapy, laser therapy, etc. Among them, surgical resection may leave scars, requiring local anesthesia and suture, with a long recovery period and possibly requiring multiple surgeries; cryotherapy may cause pain, blisters or pigmentation, and incomplete treatment may require multiple freezing; laser therapy may cause pain, scarring or pigment changes, requiring professional equipment and operation, and is expensive. Therefore, it is of great significance to develop more treatment methods for skin neoplasm.

[0004] Therefore, the present application is proposed. SUMMARY

[0005] To solve the above technical problems, the present application provides a traditional Chinese medicine composition for treating skin neoplasm and application.

[0006] Specifically, the technical scheme of the present application is as follows:

[0007] In a first aspect, the present application provides a traditional Chinese medicine composition for treating skin neoplasm, which is prepared from raw medicinal materials including the following components by weight: 0.5-2.0 parts of Huangbai, 0.5-1.5 parts of WuBeiZi, 0.5-2.0 parts of QingDai, 0.05-0.25 parts of BingPian, 0.5-1.5 parts of sodium carbonate, 0.2-1.2 parts of quicklime, 0.2-0.8 parts of sodium hydroxide, 0.5-1.5 parts of JiaDanZi, 0.6-1.5 parts of ShanCiGu, 1-1.5 parts of KuShen, and 0.1-0.3 parts of light powder.

[0008] In the Chinese medicine composition formula for treating skin neoplasm described in the present application: Huangbai is bitter in taste and cold in nature, and has the effects of clearing heat and drying dampness, purging fire and removing heat, detoxifying and treating sores. Galla chinensis is sour and astringent in taste and cold in nature, and has the effects of astringing the lung and reducing fire, astringing the intestines and stopping diarrhea, astringing sweat, stopping bleeding, and collecting dampness and healing sores. Qingdai is salty and cold in nature, and has the effects of clearing heat and detoxifying, cooling blood and removing spots, purging fire and calming shock. Bruguiera gymnorrhiza has the effect of enhancing immune function, and contains effective components such as sophoramine and bruguierin, which can stimulate local immune response, activate immune cells, and thus help the body to more effectively identify and remove infected cells; and these components have certain inhibitory effect on a variety of viruses, including human papilloma virus that causes warts; by inhibiting the replication and spread of viruses, this process not only helps to subside existing warts, but also reduces the risk of new warts, and can effectively reduce the growth and recurrence of warts. The present application mainly uses the active components contained in Bruguiera gymnorrhiza to inhibit viral replication and promote local immune response, and improve the body's ability to remove warts. Shancigu is sweet and slightly bitter in taste, and slightly cold in nature, and belongs to the liver and spleen meridians, and has the effects of clearing heat and detoxifying, resolving abscesses and removing nodules; the present application uses the effects of cooling blood and stopping bleeding, clearing heat and detoxifying, and resolving abscesses and removing nodules to treat abscesses, boils, carbuncles, scrofula, and mass and other diseases. Sophora flavescens has the effects and functions of antiviral, immune regulation, anti-inflammatory, antipruritic, and promoting skin healing, and the alkaloids contained therein have the effect of inhibiting the replication of a variety of viruses; the present application mainly uses the active components contained in Sophora flavescens to treat viral warts. Light powder is a white powder for external use, which is corrosive. Bingfen is pungent and bitter in taste, and slightly cold in nature, and belongs to the heart, liver and lung meridians, and has the effects of opening the orifices and refreshing the spirit, clearing heat and removing toxins, and clearing the eyes and removing nebula.

[0009] In the Chinese medicine composition provided by the present application, the components are compatible with each other, and have the effects of removing necrotic tissue and promoting tissue regeneration, and clearing heat and detoxifying; it can play a good health care and treatment role on various skin neoplasm, especially viral skin neoplasm; the formula is safe, does not contain any hormone and antibiotic components, and has no side effects such as allergy and dependence; the effective components can be absorbed by non-invasive epidermal point coating, and penetrate subcutaneously to decompose viral cells, so as to achieve the treatment effect of no pain and no scar.

[0010] Preferably, the Chinese medicine composition is prepared from raw medicinal materials including the following weight parts: Huangbai 1.4-1.6 parts, Galla chinensis 1.4-1.5 parts, Qingdai 1-1.5 parts, Bingfen 0.2-0.25 parts, sodium carbonate 0.8-1.2 parts, quicklime 0.8-1.1 parts, sodium hydroxide 0.4-0.6 parts, Bruguiera gymnorrhiza 1.2-1.5 parts, Shancigu 0.8-1.2 parts, Sophora flavescens 1-1.2 parts, and light powder 0.15-0.2 parts.

[0011] Preferably, the Chinese medicine composition is prepared from raw medicinal materials including the following weight parts: Huangbai 1.5 parts, Galla chinensis 1.5 parts, Qingdai 1.2 parts, Bingfen 0.25 parts, sodium carbonate 1 part, quicklime 1 part, sodium hydroxide 0.5 part, Bruguiera gymnorrhiza 1.5 parts, Shancigu 1 part, Sophora flavescens 1 part, and light powder 0.2 part.

[0012] Secondly, the present invention provides a method for preparing the traditional Chinese medicine composition for treating skin growths, wherein the raw materials are mixed in proportion, or further pulverized, or further formulated into a preparation.

[0013] In three aspects, the present invention provides a traditional Chinese medicine preparation for treating skin growths, which is made alone from the traditional Chinese medicine composition for treating skin growths, or made from the traditional Chinese medicine composition for treating skin growths and pharmaceutically acceptable excipients.

[0014] Preferably, the traditional Chinese medicine preparation is a powder, ointment, or patch.

[0015] Fourthly, the present invention provides the use of the aforementioned traditional Chinese medicine composition, or the aforementioned traditional Chinese medicine preparation, in the preparation of a medicament for treating skin growths.

[0016] Preferably, in the application, the skin growth includes at least one of the following: mole, fleshy mole, hairy mole, blood mole, spider angioma, flat wart, xanthelasma palpebrarum, filiform wart, lipoma, syringoma, sarcoma, and animal skin birthmark.

[0017] Beneficial effects:

[0018] This invention provides a traditional Chinese medicine composition and its application for treating skin growths. The traditional Chinese medicine composition for treating skin growths of this invention is prepared from the following raw materials in parts by weight: 0.5-2.0 parts of Phellodendron bark, 0.5-1.5 parts of Gallnut, 0.5-2.0 parts of Indigo naturalis, 0.05-0.25 parts of Borneol, 0.5-1.5 parts of Sodium carbonate, 0.2-1.2 parts of Quicklime, 0.2-0.8 parts of Sodium hydroxide, 0.5-1.5 parts of Brucea javanica, 0.6-1.5 parts of Cremastra appendiculata, 1-1.5 parts of Sophora flavescens, and 0.1-0.3 parts of Calomel. The traditional Chinese medicine composition for treating skin growths provided by this invention has the effects of removing necrotic tissue and promoting tissue regeneration, clearing heat and detoxifying. It has a good health-preserving and therapeutic effect on various skin growths, especially viral skin growths. Furthermore, the formula does not contain any hormones or antibiotics, and has no side effects such as allergies or dependence. It is suitable for various skin types and has good therapeutic effects. Attached Figure Description

[0019] To more clearly illustrate the technical solutions in this invention or the prior art, the accompanying drawings used in the description of the embodiments or the prior art will be described below.

[0020] Figure 1 This is a before-and-after comparison image of Case 1 in Embodiment 4 of the present invention.

[0021] Figure 2 This is a before-and-after comparison diagram of Case 2 in Embodiment 4 of the present invention.

[0022] Figure 3 This is a before-and-after comparison diagram of Case 3 in Embodiment 4 of the present invention.

[0023] Figure 4 This is a before-and-after comparison diagram of Case 4 in Embodiment 4 of the present invention. Detailed Implementation

[0024] This invention provides a traditional Chinese medicine composition for treating skin growths, which is prepared from the following raw materials in parts by weight: 0.5-2.0 parts of Phellodendron bark, 0.5-1.5 parts of Gallnut, 0.5-2.0 parts of Indigo naturalis, 0.05-0.25 parts of Borneol, 0.5-1.5 parts of Sodium carbonate, 0.2-1.2 parts of Quicklime, 0.2-0.8 parts of Sodium hydroxide, 0.5-1.5 parts of Brucea javanica, 0.6-1.5 parts of Cremastra appendiculata, 1-1.5 parts of Sophora flavescens, and 0.1-0.3 parts of Calomel.

[0025] The traditional Chinese medicine composition provided by this invention is an optimized form based on Tibetan medicine, and has three major effects: eliminating diseased tissue and promoting natural cell apoptosis, blocking viral replication and preventing recurrence, and repairing damaged cells to restore delicate skin.

[0026] The traditional Chinese medicine composition provided by this invention uses natural ingredients and is a professional formula for removing moles and warts from pure plants. It does not contain any hormones or antibiotics, is non-allergenic, non-addictive, and suitable for all skin types.

[0027] The traditional Chinese medicine composition provided by this invention is safe. It uses the natural apoptosis method and induces the diseased cells to die naturally through CAS apoptosis protease, without causing harm to the skin.

[0028] The traditional Chinese medicine composition provided by this invention has the characteristic of not leaving scars. It is a pure plant preparation, non-irritating, and will not harm the skin. It leaves no scars after mole removal.

[0029] The traditional Chinese medicine composition provided by this invention has the advantage of simple application method. Generally, it can be removed by applying it once. If the growth is larger than 0.3cm in diameter, or if it cannot be completely removed in one application, a second application can be made to the selected area. It is not afraid of water after application and will not cause infection.

[0030] The traditional Chinese medicine composition provided by this invention also has the advantage of preventing recurrence after treatment. This formula is rich in CAS apoptosis protease, which effectively acts on mutated cell tissues, accelerating the apoptosis process of skin growth cells through detoxification, tissue regeneration, elimination of tissue hyperplasia, and softening of diseased tissue. Its mechanism of action lies in rapidly blocking viral DNA replication, completely eliminating the growth environment of mutated cells, cutting off the root cause of the disease, and thus preventing the recurrence of skin problems such as moles, warts, and dermatitis. Through the intervention of CAS apoptosis protease, diseased cells are effectively cleared, promoting the body's self-repair and renewal, and maintaining the health and vitality of skin tissue. This process not only helps improve the appearance of diseased skin but also benefits overall health.

[0031] The technical solutions provided by the present invention will be described in detail below with reference to the embodiments, but they should not be construed as limiting the scope of protection of the present invention. Unless otherwise specified, the experimental methods used in the embodiments are all conventional methods; the materials and reagents used are all commercially available.

[0032] Example 1

[0033] This embodiment provides a traditional Chinese medicine composition with the following formula: 1.5 parts of Phellodendron bark, 1.5 parts of Gallnut, 1.2 parts of Indigo naturalis, 0.25 parts of Borneol, 1 part of Sodium carbonate, 1 part of Quicklime, 0.5 parts of Sodium hydroxide, 1.5 parts of Brucea javanica, 1 part of Cremastra appendiculata, 1 part of Sophora flavescens, and 0.2 parts of Calomel.

[0034] Example 2

[0035] This embodiment provides a traditional Chinese medicine composition with the following formula: 0.5 parts of Phellodendron bark, 1.5 parts of Gallnut, 2.0 parts of Indigo naturalis, 0.05 parts of Borneol, 0.5 parts of Sodium carbonate, 0.2 parts of Quicklime, 0.2 parts of Sodium hydroxide, 0.5 parts of Brucea javanica, 1.5 parts of Cremastra appendiculata, 1.5 parts of Sophora flavescens, and 0.3 parts of Calomel.

[0036] The preparation method of the traditional Chinese medicine composition provided in this embodiment is the same as that in Embodiment 1.

[0037] Example 3

[0038] This embodiment provides a traditional Chinese medicine composition with the following formula: 2.0 parts of Phellodendron bark, 0.5 parts of Gallnut, 0.5 parts of Indigo naturalis, 0.25 parts of Borneol, 1.5 parts of Sodium carbonate, 1.2 parts of Quicklime, 0.8 parts of Sodium hydroxide, 1.5 parts of Brucea javanica, 0.6 parts of Cremastra appendiculata, 1 part of Sophora flavescens, and 0.1 parts of Calomel.

[0039] The preparation method of the traditional Chinese medicine composition provided in this embodiment is the same as that in Embodiment 1.

[0040] Example 4

[0041] This embodiment uses the traditional Chinese medicine composition provided in Example 1 to prepare a medicine, which is then applied non-invasively to treat different cases, as detailed below:

[0042] Case 1: Ms. Qin, 40 years old, had a cauliflower-like fibroid the size of a one-yuan coin on her head near her ear. Using the traditional Chinese medicine ointment provided in Example 1, combined with a non-invasive application method, the fibroid was removed in 5 minutes. The procedure was performed without redness, swelling, or bleeding, and there was no subsequent recurrence. Figure 1 ).

[0043] Case 2: A 22-year-old woman from Xiamen had a sarcoma on her eyelashes that was affecting her vision. If minimally invasive surgery were used to remove the sarcoma, eyelashes would not grow back at the wound site, and scarring might be left. After 12 days of treatment with the traditional Chinese medicine ointment provided in Example 1, the sarcoma disappeared, and there was no recurrence during follow-up. Figure 2 ).

[0044] Case 3: Ms. Chang, female, 39 years old, had a black wart on her eye. Using the traditional Chinese medicine ointment provided in Example 1, combined with a non-invasive application method, the wart was removed in 2 minutes. The entire process was painless, without swelling or bleeding, and there was no recurrence afterward. Figure 3 ).

[0045] Case 4: Mr. Li, male, 46 years old, had a noticeable, painless, and non-itchy bump on his eyelid. After treatment with the traditional Chinese medicine ointment provided in Example 1, the bump disappeared and did not recur. Figure 4 ).

[0046] Case 5: Mr. Chen, male, 47 years old, had an eyelid lipoma. Because he was unwilling to undergo surgical removal, and other treatments were not very effective, he used the traditional Chinese medicine ointment provided in Example 1, combined with a non-invasive method to remove fat cells and metabolize the lipoma cyst wall. He has not had a recurrence for more than five years and his skin has returned to its original state.

[0047] Case 6: Zhang, male, 5 years old, had a peanut-sized birthmark on the corner of his mouth at birth, accompanied by hair. Laser and cryotherapy treatments at the hospital were ineffective. Using the traditional Chinese medicine formula ointment from Example 1, combined with a non-invasive application method, he achieved a complete cure within 30 days, restoring his skin to normal tissue and color. More than three years later, there has been no recurrence.

[0048] Case 7: Ms. Wang, 56 years old, had flat warts with a long history of the disease. After treatment at a local hospital, the warts recurred. She was treated with the traditional Chinese medicine formula in Example 1 and was completely cured after six months of treatment. She has not had a recurrence since.

[0049] Case 8: Mr. Zhang, male, 23 years old, had filiform warts on his neck. He had undergone laser treatment multiple times in the local area, but the wounds became infected and recurred. He was treated with the traditional Chinese medicine formula in Example 1. After two months of treatment, he was completely cured and has not had a recurrence since.

[0050] Case 9: Mr. Li, 30 years old, had moles on his face. He was successfully and completely cured after 3 months of treatment using the traditional Chinese medicine formula in Example 1.

[0051] The embodiments described above are merely illustrative of several implementations of the present invention, designed to facilitate a detailed understanding of the technical solutions of the present invention. However, they should not be construed as limiting the scope of patent protection. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of the present invention, and these modifications and improvements all fall within the scope of protection of the present invention.

Claims

1. A traditional Chinese medicine composition for treating skin growths, characterized in that, It is prepared from the following raw materials in parts by weight: 0.5-2.0 parts of Phellodendron bark, 0.5-1.5 parts of Gallnut, 0.5-2.0 parts of Indigo naturalis, 0.05-0.25 parts of Borneol, 0.5-1.5 parts of Sodium carbonate, 0.2-1.2 parts of Quicklime, 0.2-0.8 parts of Sodium hydroxide, 0.5-1.5 parts of Brucea javanica, 0.6-1.5 parts of Cremastra appendiculata, 1-1.5 parts of Sophora flavescens, and 0.1-0.3 parts of Calomel.

2. The traditional Chinese medicine composition for treating skin growths according to claim 1, characterized in that, It is prepared from the following raw materials in parts by weight: 1.4-1.6 parts of Phellodendron bark, 1.4-1.5 parts of Gallnut, 1-1.5 parts of Indigo naturalis, 0.2-0.25 parts of Borneol, 0.8-1.2 parts of Sodium carbonate, 0.8-1.1 parts of Quicklime, 0.4-0.6 parts of Sodium hydroxide, 1.2-1.5 parts of Brucea javanica, 0.8-1.2 parts of Cremastra appendiculata, 1-1.2 parts of Sophora flavescens, and 0.15-0.2 parts of Calomel.

3. The traditional Chinese medicine composition for treating skin growths according to claim 1, characterized in that, It is prepared from the following raw materials in parts by weight: 1.5 parts of Phellodendron bark, 1.5 parts of Gallnut, 1.2 parts of Indigo naturalis, 0.25 parts of Borneol, 1 part of Sodium carbonate, 1 part of Quicklime, 0.5 parts of Sodium hydroxide, 1.5 parts of Brucea javanica, 1 part of Cremastra appendiculata, 1 part of Sophora flavescens, and 0.2 parts of Calomel.

4. A method for preparing the traditional Chinese medicine composition for treating skin growths according to any one of claims 1 to 3, characterized in that, The raw materials are mixed according to the formula, or further pulverized, or further formulated into preparations.

5. A traditional Chinese medicine preparation for treating skin growths, characterized in that, It is prepared alone from the traditional Chinese medicine composition for treating skin growths as described in any one of claims 1 to 3, or prepared from the traditional Chinese medicine composition for treating skin growths as described in any one of claims 1 to 3 with pharmaceutically acceptable excipients.

6. The traditional Chinese medicine preparation for treating skin growths according to claim 5, characterized in that, The traditional Chinese medicine preparations are in the form of powder, ointment, or patch.

7. The use of the traditional Chinese medicine composition according to any one of claims 1 to 3, or the traditional Chinese medicine preparation according to any one of claims 5 to 6, in the preparation of a medicament for treating skin growths.

8. The application according to claim 7, characterized in that, The skin growths include at least one of the following: mole, fleshy mole, hairy mole, blood mole, spider angioma, flat wart, xanthelasma palpebrarum, filiform wart, lipoma, syringoma, sarcoma, and animal skin birthmark.

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