Cerebrospinal fluid sampling device for neurosurgery diagnosis

Abstract

The invention belongs to the technical field of medical equipment, and discloses a cerebrospinal fluid sampling device for neurosurgery diagnosis, the cerebrospinal fluid sampling device comprises a puncture needle, a catheter, a collecting tube and a sucker, the puncture needle is provided with a handle, and the outer side wall of the collecting tube is provided with scale marks; the liquid guide pipe is connected with a flow speed control assembly, the flow speed control assembly comprises a base body, the base body is provided with a liquid guide cavity and a control cavity, the inner side of the liquid guide cavity is rotationally connected with a rotating water wheel, the rotating water wheel is coaxially connected with a linkage disc, and the inner side of the control cavity contains shear thickening fluid; and the catheter is also connected with a flow regulator between the puncture needle and the flow rate control assembly. According to the cerebrospinal fluid collecting device, the puncture needle is communicated with the collecting tube through the catheter, and collected cerebrospinal fluid is directly collected and stored in the collecting tube, so that subsequent detection and analysis are facilitated; the flow rate control assembly is connected to the catheter to adaptively control the speed of collecting the cerebrospinal fluid, so that medical injury to a patient caused by too fast change of intracranial pressure is avoided.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical equipment, in particular to a cerebrospinal fluid sampling device for neurosurgery diagnosis. BACKGROUND

[0002] Cerebrospinal fluid is a colorless and transparent liquid existing in the ventricle and subarachnoid space, which plays a crucial role in the central nervous system: supplying brain cell nutrition, carrying away metabolic products, regulating acid-base balance, and buffering the pressure of the brain and spinal cord, and has a protective and supporting effect on the brain and spinal cord. More importantly, in the medical field, the cells and chemical components contained in the cerebrospinal fluid directly reflect the biochemical and pathological conditions of the central nervous system. Therefore, the detection of cerebrospinal fluid is the gold standard for diagnosing intracranial infection, subarachnoid hemorrhage, demyelination disease and various nervous system diseases (such as Alzheimer's disease and Parkinson's disease).

[0003] In the process of cerebrospinal fluid sampling, the stability of intracranial pressure is crucial to maintain vital signs. During sampling, the outflow rate of cerebrospinal fluid mainly depends on the pressure difference between the initial intracranial pressure during puncture and the external atmospheric pressure. If the intracranial pressure of the patient is too high, the excessive pressure difference will cause the cerebrospinal fluid to flow out too fast or too much, or too much cerebrospinal fluid to be released at one time in order to obtain sufficient sample, which may cause the intracranial pressure to drop suddenly. This sharp pressure change can induce serious complications, the most dangerous of which is brain hernia, which can endanger the patient's life.

[0004] At present, the standard method for collecting cerebrospinal fluid in clinical practice is lumbar puncture. However, the existing lumbar puncture completely relies on the experience and manual skills of the operator in controlling the flow rate. The usual method is to artificially estimate and control by observing the drop rate, intermittently clamping the pipeline or limiting the total amount of collection. This method is highly subjective and lacks objective, quantitative and continuous feedback, and cannot respond immediately and accurately to sudden pressure changes. Especially in the face of emergency patients with significantly increased intracranial pressure, the operation risk is high.

[0005] Shear thickening fluid (STF) is a new type of intelligent material. STF behaves as a low-viscosity fluid with small flow resistance under normal or low shear rate. However, once it encounters high-speed impact or shear, its viscosity will increase by several orders of magnitude, and the damping force will increase dramatically, behaving like a solid state, thereby greatly limiting or even blocking the flow. When the external force disappears, it can reversibly return to the initial low-viscosity state. This unique rheological property of "strong when strong" is highly consistent with the clinical needs of "automatic flow limiting when high pressure difference and smooth passing when low pressure difference" in the process of cerebrospinal fluid sampling. SUMMARY

[0006] This invention aims to provide a cerebrospinal fluid (CSF) sampling device for neurosurgical diagnosis. It utilizes a catheter to connect a puncture needle and a collection tube, directly collecting and storing the obtained CSF in the collection tube for subsequent testing and analysis. A flow rate control component connected to the catheter adaptively controls the CSF collection speed, preventing rapid changes in intracranial pressure that could cause medical harm to the patient. This invention solves the problems in the prior art.

[0007] To achieve the above objectives, the present invention provides the following technical solution:

[0008] A cerebrospinal fluid (CSF) sampling device for neurosurgical diagnosis includes a puncture needle, a guide tube, and a collection tube. The guide tube connects the puncture needle and the collection tube. The guide tube is connected to a flow rate control component for controlling the flow velocity of the CSF. The flow rate control component includes a base, and the base has a guide tube chamber that communicates with the guide tube. A rotating water wheel is rotatably connected to the inner side of the guide tube chamber. The base also has a control chamber. A linkage disk is coaxially fixedly connected to the rotating water wheel. The linkage disk is located inside the control chamber, and the inner side of the control chamber contains a shear-thickening fluid.

[0009] Furthermore, clamping members are connected to the upper and lower sides of the control chamber by springs. A pair of clamping members are slidably and sealingly connected to the side wall of the control chamber. The shear thickening fluid is disposed between the pair of clamping members. Both of the clamping members slide against the linkage disc to apply a pre-tightening force to it.

[0010] Furthermore, the lateral projection of the fluid guiding chamber completely coincides with the lateral projection of the rotating water wheel, and the width of the fluid guiding chamber is the same as the width of the rotating water wheel; when the rotating water wheel rotates, the blades of the rotating water wheel drive the cerebrospinal fluid to flow in the fluid guiding chamber.

[0011] Furthermore, the clamping member has an arc-shaped portion, the inner diameter of which is consistent with the outer diameter of the linkage disk; the arc-shaped portions of the two clamping members are arranged opposite each other in a "()" shape, and the outer flange of the linkage disk slides against the inner sidewall of the arc-shaped portion of the two clamping members.

[0012] Furthermore, the shear-thickening fluid contained in the control chamber is a suspension-type shear-thickening fluid.

[0013] Furthermore, the particles of the suspension-type shear-thickening fluid are SiO2, and the carrier fluid is PEG.

[0014] Furthermore, the puncture needle is provided with a handle away from the puncture end; the control chamber is connected to a guide nozzle for introducing and / or discharging shear-thickening fluid.

[0015] Furthermore, it also includes a suction cup, through which the puncture needle is slidably inserted.

[0016] Furthermore, the fluid guide tube is also connected to a flow regulator for controlling the flow of cerebrospinal fluid, and the flow regulator is located between the puncture needle and the flow rate control component.

[0017] Furthermore, the collection tube is a transparent tube, and the outer wall of the collection tube is marked with scale markings.

[0018] The principles and beneficial effects of the technical solution are as follows:

[0019] 1. This invention provides a cerebrospinal fluid (CSF) sampling device for neurosurgical diagnosis, comprising a puncture needle, a guide tube, and a collection tube, wherein the guide tube connects the puncture needle and the collection tube. During CSF sampling, the puncture needle is inserted into the patient's body, and the CSF flows through the puncture needle and guide tube into the collection tube for collection and storage, facilitating subsequent CSF detection and analysis. The guide tube is connected to a flow rate control component, which includes a base. The base has a guide chamber and a control chamber. A rotating water wheel is rotatably mounted within the guide chamber, and a linkage disc is coaxially and fixedly connected to the rotating water wheel inside the control chamber. The control chamber contains a shear-thickening fluid. During CSF collection, as the CSF flows through the guide chamber of the flow rate control component, the CSF drives the rotating water wheel to rotate, which in turn drives the linkage disc inside the control chamber to rotate. The system uses a rotating disk to shear the thickening fluid. When the cerebrospinal fluid (CSF) collection speed is too fast, the shearing speed of the disk on the CSF increases rapidly, causing the viscosity of the CSF to rise quickly. This results in a sharp increase in the damping force on the rotating disk, significantly limiting or even preventing its rotation. This, in turn, limits the rotation of the water wheel, thus restricting the flow rate of the CSF to prevent excessively rapid collection and rapid changes in intracranial pressure. When the CSF collection speed decreases, the viscosity of the thickening fluid gradually decreases, reducing the damping force on the rotating disk (water wheel) and ensuring that the CSF can flow smoothly into the collection tube through the drainage chamber. In other words, this flow rate control component can adaptively adjust the flow rate of CSF within the drainage chamber to ensure smooth collection and avoid excessively rapid collection.

[0020] 2. The present invention provides a cerebrospinal fluid sampling device for neurosurgical diagnosis. The upper and lower sides of the control chamber are connected to clamping members via springs. Each pair of clamping members slides against a linkage disc to apply a pre-tightening force, requiring the rotating water wheel to rotate under a certain impact. This impact originates from the pressure difference between intracranial pressure and the external environment, causing cerebrospinal fluid flow. By applying a pre-tightening force to the linkage disc, a certain pressure difference between intracranial pressure and the external environment is ensured, thereby guaranteeing the stability of intracranial pressure. The pair of clamping members are slidably sealed to the side walls of the control chamber. A shear-thickening fluid is positioned between the clamping members, restricting its movement area and preventing it from adhering to the springs and affecting their function. This ensures the effectiveness of the springs in contacting the clamping members and guarantees the functionality of the entire device. Furthermore, the shear-thickening fluid is completely sealed within the control chamber and between the two clamping members, preventing it from contacting the cerebrospinal fluid and thus avoiding contamination / affecting the collected cerebrospinal fluid. The transverse projection of the fluid-conducting chamber completely coincides with the transverse projection of the rotating waterwheel. The width of the fluid-conducting chamber is the same as the width of the rotating waterwheel. When the rotating waterwheel rotates, its blades drive the cerebrospinal fluid (CSF) to flow within the fluid-conducting chamber. This ensures that the CSF can only flow smoothly within the fluid-conducting chamber through the driving force of the rotating waterwheel blades (the CSF can only flow smoothly through the fluid-conducting chamber by impacting the rotating waterwheel blades and causing them to rotate). Therefore, the flow of CSF can be controlled by controlling the rotation of the rotating waterwheel, improving the accuracy and effectiveness of CSF flow rate control. The clamping components have an arc-shaped portion, the inner diameter of which is the same as the outer diameter of the linkage disk. The arc-shaped portions of the two clamping components are arranged opposite each other in a "()" shape. The outer flange of the linkage disk slides against the inner sidewall of the arc-shaped portion of the two clamping components, effectively increasing the contact area between the clamping components and the linkage disk, further enhancing the force exerted by the clamping components on the linkage disk.

[0021] 3. The present invention provides a cerebrospinal fluid sampling device for neurosurgical diagnosis, wherein the shear-thickening fluid contained in the control chamber is a suspension-type shear-thickening fluid. The basic principle of the suspension-type shear-thickening fluid is the hydrodynamic interaction between particles, mainly composed of high-hardness particles of nanometer or micrometer size dispersed in a compatible carrier fluid. At low shear rates, the particles are lubricated by the carrier fluid and can slide relatively freely across each other, and the fluid exhibits a viscous liquid behavior. However, at high shear rates, the particles are forced to approach each other, the lubricating layer of the liquid between the particles is destroyed, the hydrodynamic interaction becomes dominant, and temporary, entangled "clusters" or "force chains" are formed between the particles, which greatly hinders the flow, resulting in a sharp increase in viscosity or even solidification. By utilizing the control of the rotation speed of the linkage disc / rotating water wheel, the adaptive control of the cerebrospinal fluid collection flow rate can be effectively achieved. Suspension-type shear-thickening fluids use SiO2 particles and PEG as the carrier fluid. The silica (SiO2) / polyethylene glycol (PEG) system is the most classic and extensively studied suspension-type shear-thickening fluid. The molecular weight of PEG (e.g., PEG200, PEG400) and the concentration, shape (spherical, gas-phase), and particle size (typically 100-500 nanometers) of SiO2 particles have a decisive influence on the thickening effect. For example, by changing the concentration of SiO2, the critical shear rate at which shear thickening occurs can be precisely set, thereby matching the safe flow rate required by the design.

[0022] 4. This invention provides a cerebrospinal fluid (CSF) sampling device for neurosurgical diagnosis. The puncture needle has a handle at the distal end for easy manipulation. A control chamber is connected to a nozzle for introducing and / or discharging shear-thickening fluids. Different compositions and concentrations of shear-thickening fluids can be injected or discharged into the control chamber to meet various clinical needs. The entire CSF sampling device also includes a suction cup. The puncture needle slides through the suction cup. During puncture, the suction cup adheres to the patient's skin, and the puncture needle passes through the suction cup and enters the patient's body. The suction cup guides and limits the puncture needle, ensuring accurate puncture location and linearity of the puncture process. The drainage tube is also connected to a flow regulator to control the CSF flow rate. The flow rate of the CSF in the drainage tube can be controlled by adjusting the flow rate. The collection tube is transparent, and its outer wall has graduations, allowing medical personnel to visually monitor the amount of CSF collected, ensuring a sufficient sample volume and avoiding over-collection. Attached Figure Description

[0023] Figure 1 This is a schematic diagram of the structure of a cerebrospinal fluid sampling device for neurosurgical diagnosis according to the present invention;

[0024] Figure 2 This is a front view of a cerebrospinal fluid sampling device for neurosurgical diagnosis according to the present invention;

[0025] Figure 3 for Figure 2 Sectional view of AA;

[0026] Figure 4 for Figure 3 Sectional view of BB;

[0027] Figure 5 This is a side view of a cerebrospinal fluid sampling device for neurosurgical diagnosis according to the present invention;

[0028] Figure 6 for Figure 5 A sectional view of CC.

[0029] The names of the corresponding labels in the attached diagram are:

[0030] 1. Puncture needle, 2. Handle, 3. Fluid guide tube, 4. Collection tube, 5. Flow rate control component, 6. Suction cup, 7. Flow regulator, 8. Matrix, 9. Fluid guide chamber, 10. Rotating water wheel, 11. Control chamber, 12. Linkage disc, 13. Clamping component, 14. Spring, 15. Guide nozzle. Detailed Implementation

[0031] The present invention will now be described in further detail with reference to the accompanying drawings and embodiments:

[0032] Example 1: As Figures 1 to 6 As shown, a cerebrospinal fluid sampling device for neurosurgical diagnosis includes a puncture needle 1, a fluid guide tube 3, a collection tube 4, and a suction cup 6. The puncture needle 1 has a handle 2 at the end away from the puncture point. The puncture point of the puncture needle 1 is slidably inserted into the suction cup 6. The fluid guide tube 3 connects the puncture needle 1 and the collection tube 4. The collection tube 4 is a transparent tube, and the outer wall of the collection tube 4 has scale markings. The fluid guide tube 3 is connected to a flow rate control component 5 for controlling the flow rate of cerebrospinal fluid. The flow rate control component 5 includes a base 8. The base 8 has a fluid guide chamber 9 that communicates with the fluid guide tube 3. A rotating water wheel 10 is rotatably connected to the inner side of the fluid guide chamber 9. The base 8 also has a control chamber 11. A linkage disc 12 is coaxially fixedly connected to the rotating water wheel 10. The linkage disc 12 is located inside the control chamber 11, and the inner side of the control chamber 11 contains a shear-thickening fluid.

[0033] In this embodiment, the lateral projection of the fluid guiding chamber 9 completely coincides with the lateral projection of the rotating water wheel 10, and the width of the fluid guiding chamber 9 is the same as the width of the rotating water wheel 10. When the rotating water wheel 10 rotates, the blades of the rotating water wheel 10 drive the cerebrospinal fluid to flow in the fluid guiding chamber 9. Clamping members 13 are connected to the upper and lower sides of the control chamber 11 via springs 14. A pair of clamping members 13 are slidably and sealingly connected to the sidewalls of the control chamber 11. Shear-thickening fluid is disposed between the pair of clamping members 13. Both clamping members 13 slide against the linkage disk 12 to apply a pre-tightening force. The clamping members 13 have an arc-shaped portion, the inner diameter of which is the same as the outer diameter of the linkage disk 12. The arc-shaped portions of the two clamping members 13 are arranged opposite each other in a “()” shape, and the outer flange of the linkage disk 12 slides against the inner sidewall of the arc-shaped portion of the two clamping members 13.

[0034] In addition, the control chamber 11 is connected to a guide nozzle 15 for introducing and / or discharging shear-thickening fluid, and the fluid guide tube 3 is connected to a flow regulator 7 for controlling the flow rate of cerebrospinal fluid. The flow regulator 7 is located between the puncture needle 1 and the flow rate control component 5.

[0035] The specific implementation process is as follows:

[0036] When using this sampling device, first align the center of the suction cup 6 with the puncture point on the patient's body surface, and attach the suction end of the suction cup 6 to the patient's body surface; then, holding the handle 2, insert the puncture needle 1 into the patient's body, and slide the roller along the axis of the flow regulator 7 to collect the patient's cerebrospinal fluid. During the cerebrospinal fluid collection process, the flow rate control component 5 adaptively controls the flow rate of the cerebrospinal fluid, the flow rate of the cerebrospinal fluid is controlled by the flow regulator 7, and the amount of cerebrospinal fluid collected is identified by the scale markings on the collection tube 4 until the clinical sampling requirements are met.

[0037] During puncture, the suction cup 6 is attached to the patient's body surface, and the puncture needle 1 passes through the disk and enters the patient's body. The suction cup 6 guides and limits the puncture needle 1 to ensure the accuracy of the puncture position and the straightness of the puncture process. The puncture needle 1 is provided with a handle 2 at the end away from the puncture point to facilitate the operation of the puncture needle 1.

[0038] During the collection of cerebrospinal fluid (CSF), the flow of CSF drives the rotating water wheel 10 to rotate. The rotation of the water wheel 10 drives the linkage disc 12 in the control chamber 11 to rotate, shearing the shear-thickening fluid. When the speed of CSF collection is too fast, the shearing speed of the linkage disc 12 on the shear-thickening fluid increases, and the viscosity of the shear-thickening fluid increases rapidly. The damping force on the rotation of the linkage disc 12 increases sharply, greatly limiting or even preventing the rotation of the linkage disc 12, thereby limiting the rotation of the rotating water wheel 10, and thus limiting the flow speed of CSF to avoid the CSF collection speed being too fast, which would cause the patient's intracranial pressure to change too quickly. When the speed of CSF collection decreases, the viscosity of the shear-thickening fluid gradually decreases, reducing the damping force on the linkage disc 12 (rotating water wheel 10), ensuring that the CSF can flow smoothly into the collection tube 4 through the drainage chamber 9. The control chamber 11 has clamping members 13 connected to its upper and lower sides via springs 14. Each pair of clamping members 13 slides against the linkage disc 12 to apply a pre-tightening force, so that the rotating water wheel 10 can only rotate under a certain impact. The impact on the rotating water wheel 10 comes from the flow of cerebrospinal fluid caused by the pressure difference between intracranial pressure and the outside. By applying a pre-tightening force to the linkage disc 12, a certain pressure difference between intracranial pressure and the outside is ensured, thereby ensuring the stability of intracranial pressure. The pair of clamping members 13 are slidably sealed to the side wall of the control chamber 11. The shear thickening fluid is placed between the pair of clamping members 13 to restrict the movement area of ​​the shear thickening fluid, preventing it from adhering to the springs 14 and affecting their function, thereby ensuring the effect of the springs 14 on the clamping members 13 and ensuring the functionality of the entire device. Moreover, the shear thickening fluid is completely sealed between the control chamber 11 and the two clamping members 13, so that it never comes into contact with the cerebrospinal fluid, thus avoiding contamination / affecting the collected cerebrospinal fluid by the shear thickening fluid. Furthermore, the lateral projection of the fluid-conducting chamber 9 completely coincides with the lateral projection of the rotating waterwheel 10, and the width of the fluid-conducting chamber 9 is the same as the width of the rotating waterwheel 10. When the rotating waterwheel 10 rotates, the blades of the rotating waterwheel 10 drive the cerebrospinal fluid to flow within the fluid-conducting chamber 9. This ensures that the cerebrospinal fluid can only flow smoothly within the fluid-conducting chamber 9 through the drive of the blades of the rotating waterwheel 10 (the cerebrospinal fluid can only flow smoothly through the fluid-conducting chamber by impacting the blades of the rotating waterwheel 10 to make it rotate). Thus, the flow of cerebrospinal fluid can be controlled by controlling the rotation of the rotating waterwheel 10, improving the accuracy and effectiveness of cerebrospinal fluid flow rate control. The arc-shaped portions of the two clamping members 13 are arranged in a "()" shape, and the outer flange of the linkage disk 12 slides against the inner sidewall of the arc-shaped portion of the two clamping members 13, effectively increasing the contact area between the clamping members 13 and the linkage disk 12, and improving the force exerted by the clamping members 13 on the linkage disk 12.

[0039] The flow rate of cerebrospinal fluid in the drainage tube 3 can be controlled by adjusting the flow rate of the collected cerebrospinal fluid using a flow rate regulator. The collection tube 4 is a transparent tube with graduation markings on its outer wall, allowing medical staff to visually know the amount of cerebrospinal fluid collected in the collection tube 4, ensuring that the sample volume is accurate and avoiding over-collection.

[0040] Example 2: In this example, the shear-thickening fluid contained in the control chamber 11 is a suspension-type shear-thickening fluid. Specifically, the particles of the suspension-type shear-thickening fluid are SiO2, and the carrier fluid is PEG. When using the cerebrospinal fluid sampling device of this example, the concentration of SiO2 can be changed when introducing the suspension-type shear-thickening fluid into the guide nozzle 15 to precisely set the critical shear rate at which the suspension-type shear-thickening fluid in the strong control chamber undergoes shear thickening, thereby matching the safe flow rate required by the design. The remaining structure, shape, connection method, implementation method, and beneficial effects are the same as in Example 1, and will not be repeated in this example.

[0041] The above descriptions are merely embodiments of the present invention, and common knowledge regarding specific technical solutions or characteristics is not elaborated upon here. It should be noted that those skilled in the art can make various modifications and improvements without departing from the technical solutions of the present invention, and these should also be considered within the scope of protection of the present invention. These modifications and improvements will not affect the effectiveness of the implementation of the present invention or the practicality of the patent. The scope of protection claimed in this application should be determined by the content of its claims, and the specific embodiments described in the specification can be used to interpret the content of the claims.

Claims

1. A cerebrospinal fluid sampling device for neurosurgical diagnosis, comprising a puncture needle, a catheter, and a collection tube, the catheter connecting the puncture needle and the collection tube; characterized in that, The catheter is connected with a flow rate control assembly for controlling the flow rate of the cerebrospinal fluid, the flow rate control assembly comprises a base body, the base body is provided with a catheter chamber in communication with the catheter, the catheter chamber is rotatably connected with a rotating water wheel on the inner side, the base body is further provided with a control chamber, the rotating water wheel is coaxially fixedly connected with a linkage disc, the linkage disc is arranged on the inner side of the control chamber, and the control chamber is filled with a shear thickening fluid.

2. The neurosurgical diagnostic cerebrospinal fluid sampling device of claim 1, wherein, The upper and lower sides of the control chamber are connected with clamping pieces through springs, a pair of clamping pieces are in sliding sealing connection with the side wall of the control chamber, the shear thickening fluid is arranged between the pair of clamping pieces, and the pair of clamping pieces are in sliding abutment with the linkage disc to apply a pre-tightening force to the linkage disc.

3. The neurosurgical diagnostic cerebrospinal fluid sampling device of claim 2, wherein, The lateral projection of the catheter chamber is completely coincident with the lateral projection of the rotating water wheel, and the width of the catheter chamber is consistent with the width of the rotating water wheel; when the rotating water wheel rotates, the blades of the rotating water wheel drive the cerebrospinal fluid to flow in the catheter chamber.

4. The neurosurgical diagnostic cerebrospinal fluid sampling device of claim 2, wherein, The clamping piece is provided with an arc-shaped portion, the inner diameter of the arc-shaped portion is consistent with the outer diameter of the linkage disc; the arc-shaped portions of the two clamping pieces are oppositely arranged in a ( ) type, and the outer side flange of the linkage disc is in sliding abutment with the inner side walls of the arc-shaped portions of the two clamping pieces.

5. The neurosurgical diagnostic cerebrospinal fluid sampling device of claim 1, wherein, The shear thickening fluid filled in the control chamber is a suspension type shear thickening fluid.

6. The neurosurgical diagnostic cerebrospinal fluid sampling device of claim 5, wherein, The particles of the suspension type shear thickening fluid are SiO2, and the carrier liquid is PEG.

7. The neurosurgical diagnostic cerebrospinal fluid sampling device of claim 1, wherein, The puncture needle is provided with a handle away from the puncture end; the control chamber is communicated with a through mouth for guiding the shear thickening fluid to be introduced and / or discharged.

8. The neurosurgical diagnostic cerebrospinal fluid sampling device of claim 1, wherein, Further comprising a suction disc, the puncture needle is slidingly arranged in the suction disc.

9. The neurosurgical diagnostic cerebrospinal fluid sampling device of claim 1, wherein, The catheter is further connected with a flow rate regulator for controlling the flow rate of the cerebrospinal fluid, and the flow rate regulator is arranged between the puncture needle and the flow rate control assembly.

10. The neurosurgical diagnostic cerebrospinal fluid sampling device of claim 1, wherein, The collection tube is a transparent tube, and the outer side wall of the collection tube is provided with a scale mark.

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