Plant-derived composition and application thereof
By regulating the skin's microecology through a combination of plant extracts, the problems of drug resistance and allergies caused by bactericides in cosmetics are solved, achieving effective inhibition of Propionibacterium acnes and improvement of skin health.
Patent Information
- Application Number
- CN202511781573.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-11-29
- Publication Date
- 2026-01-23
AI Technical Summary
Existing cosmetics often contain bactericides, which can easily disrupt the skin's surface microecological balance with long-term use, leading to drug resistance and allergies. They are also highly irritating and difficult to effectively inhibit Propionibacterium acnes.
This product uses a plant composition of extracts from eucalyptus leaves, grapefruit peel, euphorbia humifusa, neem leaves, and clove flowers as a cosmetic ingredient to regulate the skin's microecology, inhibit the growth of Propionibacterium acnes, and promote the growth of beneficial bacteria.
It effectively inhibits Propionibacterium acnes, reduces the risk of allergies, maintains the skin's microecological balance, is suitable for all skin types, especially sensitive skin, and has no risk of drug resistance.
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Abstract
Description
TECHNICAL FIELD
[0001] The application discloses a composition and application thereof, in particular, a plant-derived composition and application thereof, and belongs to the technical field of cosmetics. BACKGROUND
[0002] Propionibacterium acnes is a gram-positive anaerobic short bacillus, which often inhabits in our skin follicles and sebaceous glands, and is one of normal flora on the skin. When the sebaceous glands are blocked due to excessive secretion of sebum, the Propionibacterium acnes will multiply in large quantities, causing the familiar acne, acne and other skin problems. It can also decompose sebum to produce free fatty acids, which can stimulate the surrounding tissues and cause inflammatory reactions. Worse still, it can also produce some low molecular peptides to attract white blood cells to concentrate in the follicle sebaceous gland unit, further aggravating inflammation. In daily care, in addition to choosing mild cleansing products to remove excess oil, dirt and aged keratin on the skin surface, cosmetics capable of inhibiting Propionibacterium acnes can also be used simultaneously to reduce the occurrence of acne.
[0003] Most of the cosmetics on the market that claim to be able to inhibit Propionibacterium acnes add some bactericides, or products containing sulfur and acid. Long-term use can destroy the balance of the skin surface microecology, and at the same time, it can cause tolerance, resulting in a significant decrease in effect. In addition, such products are highly irritating and prone to allergic reactions.
[0004] Therefore, it is necessary to invent a pure plant combination composition capable of inhibiting Propionibacterium acnes. SUMMARY
[0005] In view of the above problems, the application aims to provide a plant-derived composition, which has the characteristics of high safety, natural mildness and less skin irritation, and is less likely to cause adverse reactions such as allergy, swelling and itching, and is suitable for various skin types, especially sensitive skin. The application also provides the application of the composition.
[0006] To this end, the first technical solution provided by the application is as follows: A plant-derived composition, comprising the following components: Eucalyptus globulus leaf extract, grapefruit peel extract and Eupatorium fortunei extract.
[0007] Further, the composition further comprises neem leaf extract.
[0008] Further, the composition further comprises clove flower extract.
[0009] Further, the composition consists of the following components: Eucalyptus globulus leaf extract, grapefruit peel extract, Eupatorium fortunei extract, neem leaf extract and clove flower extract.
[0010] Further, the composition comprises the following components in parts by weight: 0.01-5 parts of Eucalyptus leaf extract, 0.01-8 parts of grapefruit peel extract, 0.01-16 parts of Bloodwort extract, 0.01-18 parts of Neem leaf extract, and 0.01-6 parts of clove flower extract.
[0011] Further, the composition comprises the following components in parts by weight: 0.01-1 parts of Eucalyptus leaf extract, 0.01-2 parts of grapefruit peel extract, 0.01-5 parts of Bloodwort extract, 0.01-5 parts of Neem leaf extract, and 0.01-1 parts of clove flower extract.
[0012] The second technical solution provided by the present invention is: the composition is applied to cosmetics.
[0013] Furthermore, the cosmetic product is one or more of the following: toner, lotion, serum, cream, mask, or mud mask.
[0014] Furthermore, the composition is added to the cosmetic at an amount of 0.1-20% of the total weight of the cosmetic.
[0015] Furthermore, the composition is added to the cosmetic at an amount of 0.1-15% of the total weight of the cosmetic.
[0016] Compared with the prior art, the present invention has the following beneficial effects:
[0017] The technical solution of this invention is highly safe, natural and gentle, with less skin irritation, and is less likely to cause adverse reactions such as allergies, redness, swelling, and itching. It is suitable for all skin types, especially sensitive skin.
[0018] The technical solution of this invention has no risk of drug resistance. Conventional bactericides are prone to causing Propionibacterium acnes to develop drug resistance, which will gradually reduce the effectiveness. In contrast, plant ingredients have diverse mechanisms of action, are not prone to causing bacteria to develop drug resistance, and can exert a stable inhibitory effect for a long time.
[0019] The plant extracts in the technical solution of this invention can regulate the skin microecology. While the bactericide kills Propionibacterium acnes, it also kills some beneficial bacteria on the skin, thereby disrupting the skin microecology. The plant ingredients inhibit Propionibacterium acnes while promoting the growth of beneficial bacteria, thereby improving the overall health of the skin.
[0020] The components used in the technical solution of this invention are abundant plant resources that are widely distributed and easy to obtain. By making reasonable use of plant resources, sustainable development can be achieved and the market demand for plant components can be met. Detailed Implementation
[0022] The claims of the present invention will be further described in detail below with reference to specific embodiments, but this does not constitute any limitation on the present invention. Any limited modifications made by any person within the scope of protection of the claims of the present invention are still within the scope of protection of the claims of the present invention.
[0023] Example 1
[0024] A plant-derived composition comprising the following ingredients in weight percentage: 0.01g clove flower extract, 0.01g euphorbia humifusa extract, 0.01g neem leaf extract, 0.01g eucalyptus leaf extract, and 0.01g grapefruit peel extract.
[0025] Example 2
[0026] A plant-derived composition comprising the following ingredients by weight percentage: 1g clove flower extract, 2g euphorbia humifusa extract, 5g neem leaf extract, 5g eucalyptus leaf extract, and 1g grapefruit peel extract.
[0027] Example 3
[0028] A plant-derived composition comprising the following ingredients by weight percentage: 5g clove flower extract, 8g euphorbia humifusa extract, 16g neem leaf extract, 18g eucalyptus leaf extract, and 16g grapefruit peel extract.
[0029] To demonstrate the effectiveness of this invention, comparative experimental examples are provided below: Comparative Example 1
[0030] Compared with Example 1, only the clove flower extract was removed, and everything else remained unchanged.
[0031] Comparative Example 2
[0032] Compared with Example 1, only the extract of Ophiopogon japonicus was removed, and everything else remained unchanged.
[0033] Comparative Example 3
[0034] Compared with Example 1, only the Indian neem leaf extract was removed, and everything else remained unchanged.
[0035] Comparative Example 4
[0036] Compared with Example 1, only the eucalyptus leaf extract was removed, and everything else remained unchanged.
[0037] Comparative Example 5
[0038] Compared with Example 1, only the grapefruit peel extract was removed, and everything else remained unchanged.
[0039] Table 1. Composition Table of Examples and Comparative Examples
[0040]
[0041] To better illustrate the advantages of this invention, the following verification scheme provided by this invention is given:
[0042] Test 1: Anti-aging Test
[0043] Experiment 1: Accelerated Stability Performance Test
[0044] This test is a one-month accelerated stability test of the compositions obtained in Examples 1-3 and Comparative Examples 1-3.
[0045] The composition prepared above was subjected to stability tests under the following conditions: room temperature, light exposure (natural light), low temperature (-15℃), high temperature (45℃), high and low temperature cycling (45℃ / -15℃ for 24 hours each), and refrigeration (5℃). The data are recorded in Table 2.
[0046] Table 2. Results of accelerated stability test of the composition after one month
[0047]
[0048] As can be seen from the experimental results in Table 2, there were no obvious abnormalities in the stability of Examples 1-3 and Comparative Examples 1-3, and the stability was passed.
[0049] Experimental Example 2: Human Skin Patch Test
[0050] This test used the compositions obtained in Examples 1-3 and Comparative Examples 1-5, prepared as 10% aqueous solutions. Following the human skin patch test in the "2022 Cosmetic Safety Technical Specifications," skin reactions were observed at 30 min (after the indentation disappeared), 24 h, and 48 h, and the results were recorded. The data are recorded in Table 3.
[0051] Table 3. Results of human skin patch test of the composition
[0052]
[0053] As shown in Table 3, the composition is non-irritating when added up to 10%, and can be used safely within this range.
[0054] Experimental Example 3: Propionibacterium acnes inhibition test
[0055] The plate-punching method was used. A concentration of 5 × 10⁴ CFU / ml of *Propionibacterium acnes* was evenly spread onto the surface of nutrient agar plates using a sterile cotton swab and allowed to dry at room temperature for 10 min. Then, a 6 mm diameter sterile circular punch was used to punch holes. 2 ml of the composition samples prepared in Examples 1-3 and Comparative Examples 1-3 were diluted 100 times with physiological saline and added to the holes until full, without overflowing. Three parallel experiments were performed. Subsequently, the petri dishes were placed in a constant temperature incubator at (37±1) °C for 24 h. Afterward, the plates were observed, and the diameter (cm) of the inhibition zone was measured using calipers, with the outer edge of the inhibition zone showing no colony growth as the boundary. Results were interpreted according to the National Committee for Clinical Trials Standards (NCCLS) standards: inhibition zone diameter < 8 mm was considered insensitive, 8–13 mm was considered lowly sensitive, 13–19 mm was considered moderately sensitive, and >19 mm was considered highly sensitive. The results are shown in Table 4.
[0056] Table 4. Test results of the antibacterial effect of the composition.
[0057]
[0058] As shown in Table 4, the diameter of the inhibition zone of the composition samples in Examples 1-3 is all above 20 cm, indicating that they are highly sensitive to Propionibacterium acnes and have a good antibacterial effect. In contrast, the diameter of the inhibition zone of the composition samples in Comparative Examples 1-5 is all below 13 cm, indicating that they are only slightly sensitive to Propionibacterium acnes and have no good antibacterial effect.
[0059] In summary, this invention studies plant-based ingredients in the field of cosmetic technology and prepares compositions through reasonable and scientific formulation. These compositions are natural and non-irritating, and can effectively inhibit Propionibacterium acnes. When applied to cosmetics, they can effectively play an antibacterial role.
[0060] The above embodiments are preferred embodiments of the present invention, but the embodiments of the present invention are not limited to the above embodiments. Any changes, modifications, substitutions, combinations, or simplifications made without departing from the spirit and principle of the present invention shall be considered equivalent substitutions and shall be included within the protection scope of the present invention.
Claims
1. A plant-derived composition, characterized in that, It includes the following components: Eucalyptus leaf extract, grapefruit peel extract, and Euphorbia lathyris extract.
2. The composition according to claim 1, characterized in that, The composition also includes neem leaf extract.
3. The composition according to claim 1, characterized in that, The composition also includes clove flower extract.
4. The composition according to claim 1, characterized in that, The composition comprises the following components: eucalyptus leaf extract, grapefruit peel extract, holly extract, neem leaf extract, and clove flower extract.
5. The composition according to claim 4, characterized in that, The composition comprises the following components in parts by weight: 0.01-5 parts of Eucalyptus leaf extract, 0.01-8 parts of grapefruit peel extract, 0.01-16 parts of Bloodwort extract, 0.01-18 parts of Neem leaf extract, and 0.01-6 parts of clove flower extract.
6. The composition according to claim 5, characterized in that, The composition comprises the following components in parts by weight: 0.01-1 parts of Eucalyptus leaf extract, 0.01-2 parts of grapefruit peel extract, 0.01-5 parts of Blood-activating Herb extract, 0.01-5 parts of Neem leaf extract, and 0.01-1 parts of clove flower extract.
7. The use of a composition according to any one of claims 1-6, characterized in that, The composition is used in cosmetics.
8. The application according to claim 7, characterized in that, The cosmetic product is one or more of the following: toner, lotion, serum, cream, mask, or mud mask.
9. The application according to claim 7, characterized in that, The composition is added to the cosmetic at a rate of 0.1-20% of the total weight of the cosmetic.
10. The application according to claim 7, characterized in that, The composition is added to the cosmetic at a rate of 0.1-15% of the total weight of the cosmetic.