A strain of streptomyces spheroides jiq021 and application thereof

By screening Streptomyces rustii strain JQ021 and its metabolic extracts, a microbial preparation was prepared, which solved the problem of the narrow antibacterial spectrum of existing antagonistic strains, achieved high-efficiency inhibition of a variety of pathogenic Vibrio aquatic bacteria, and provided a safe biological control solution.

CN121379901BActive Publication Date: 2026-04-10OCEAN UNIV OF CHINA
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Patent Information

Application Number
CN202511970221.6
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-12-25
Publication Date
2026-04-10
Estimated Expiration
2045-12-25

AI Technical Summary

Technical Problem

Existing antagonistic strains used in aquaculture have a narrow antibacterial spectrum and are difficult to synergistically inhibit a variety of important Vibrio species, especially Vibrio parahaemolyticus, Vibrio alginolyticus, and Vibrio erwens.

Method used

We screened and provided Streptomyces rustii strain JQ021 and its metabolic extracts, and prepared them into microbial preparations or antimicrobial compositions for highly efficient and broad-spectrum inhibition of a variety of pathogenic Vibrio bacteria in aquatic organisms.

Benefits of technology

It achieves highly efficient and broad-spectrum inhibition of Vibrio parahaemolyticus, Vibrio alginolyticus and Vibrio erwinis, providing a safe and efficient biological control solution and avoiding the problem of drug resistance.

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Abstract

The present application relates to the field of microbiological technology, and specifically discloses a strain of Streptomyces rutilocolore JQ021 and its application. The strain has been preserved in the China Center for Type Culture Collection on October 9, 2025, and the preservation number is CCTCC NO: M 20252186. The strain JQ021 and its culture, metabolic extract produced therefrom all exhibit high and broad-spectrum inhibitory activity against various aquatic pathogenic Vibrio, especially Vibrio parahaemolyticus, Vibrio alginolyticus and Vibrio owensii. The present application also relates to a microbial preparation and an antibacterial composition comprising the strain or the metabolic extract, and the application thereof in preparing a preparation for preventing and treating aquatic vibrio disease. The strain provides a valuable microbial resource for developing safe and efficient antibiotic substitutes.
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