Waste treatment method in radiopharmaceutical production process

By generating AgI crystals from DNA-silver nanocomposites with iodine-131 and combining this with vacuum evaporation and cement solidification technology, the problem of separating and solidifying iodine-131 wastewater during radiopharmaceutical production was solved, achieving efficient and safe radioactive waste treatment and reducing environmental pollution risks and treatment costs.

CN121609458APending Publication Date: 2026-03-06HUAYI PHARM (GUANGDONG) CO LTD
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Patent Information

Application Number
CN202511511926.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-10-22
Publication Date
2026-03-06

AI Technical Summary

Technical Problem

Iodine-131 is difficult to separate effectively from wastewater generated during the production of radiopharmaceuticals, resulting in a high risk of environmental pollution. Traditional evaporation and concentration technologies are inefficient and have the problem of entrainment of volatile iodine-131.

Method used

DNA-silver nanocomposite material is used to combine with iodine-131 to generate AgI crystals. Vacuum evaporation process and cement solidification technology are used to ensure the fixation and separation of iodine-131. The condensate is tested by high-purity germanium gamma spectrometry to ensure that it meets the discharge standards. Double-layer stainless steel storage containers are used for safe storage.

Benefits of technology

It achieves efficient separation and solidification of radioactive waste, reduces the risk of environmental pollution, improves treatment efficiency, reduces water waste, and ensures the safe management and long-term storage of radioactive waste.

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Abstract

The invention discloses a waste treatment method in a radiopharmaceutical production process, which comprises the following steps: adding a DNA-silver nano composite material into wastewater, so that silver ions are combined with iodine-131 to generate stable silver iodide crystals, thereby fixing radionuclides in the wastewater; the risk of iodine-131 volatilization is reduced by adopting a vacuum evaporation process, and water is ensured to be separated from radioactive pollutants; condensate water is discharged after reaching the standard through detection, and concentrated waste is subjected to curing treatment; by mixing concentrated waste with cement and adding a silicate additive, the physical stability and chemical inertness of a solidified body are enhanced, and the possibility of leakage is reduced; and finally, safely storing the cured concentrated waste in a special storage container. According to the method, efficient and safe radioactive waste management is achieved through the synergistic effect of a series of steps, the safety of long-term storage is greatly improved, and the method has great significance in protecting human health and protecting the ecological environment from radioactive contamination.
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