Lysozyme and BZK-based degerming and acarus-killing laundry detergent and preparation method thereof

Abstract

The degerming and acarus killing laundry detergent based on lysozyme and BZK is prepared from the following raw materials in percentage by mass: 0.01 to 0.5 percent of lysozyme, 0.01 to 1.0 percent of BZK benzalkonium chloride, 0.02 to 1.5 percent of triclosan, 0.01 to 1.5 percent of chelating agent, 12 to 35 percent of composite surfactant, 0.01 to 0.5 percent of protease, 0.01 to 0.5 percent of lipase, 0.05 to 2.0 percent of modified cellulose derivative, 0.01 to 1.5 percent of pH regulator and the balance of deionized water. According to the invention, the lysozyme can synergistically remove bacteria and mites, the effect is remarkable, after the lysozyme destroys bacterial cell walls, the BZK and the triclosan can quickly kill residual microorganisms, the 20-min bacteriostasis rate on escherichia coli, staphylococcus aureus and candida albicans is greater than or equal to 99.9% aiming at mite body surface penetration, the mite removal rate is greater than or equal to 99.9%, and the problem that the effect of a single component is limited is solved.

Description

Technical Field

[0001] This invention relates to the field of daily chemical technology, specifically to an antibacterial and anti-mite laundry detergent based on lysozyme and BZK, and its preparation method. Background Technology

[0002] With increasing consumer health awareness, the demand for antibacterial and anti-mite functions in laundry detergents is becoming increasingly urgent. Currently, most antibacterial laundry detergents on the market use a single active ingredient (such as triclosan, silver ions, or quaternary ammonium salts), which has the following drawbacks: First, they have a narrow antibacterial spectrum, with limited effectiveness against mites and drug-resistant bacteria (such as Escherichia coli, Staphylococcus aureus, and Candida albicans), making it difficult to achieve the dual effect of "antibacterial + anti-mite." Second, they rely on high temperatures (above 40℃) to achieve optimal results; their activity decreases at low temperatures, failing to meet energy-saving washing requirements. Third, to ensure effectiveness, the concentration of bactericides is often increased, leading to significant skin irritation, especially unsuitable for allergy sufferers. Fourth, bactericides easily remain on fabric surfaces, potentially causing fabric stiffening and skin itching after repeated use. Furthermore, the existing detergent cleaning systems have poor compatibility with bactericidal ingredients; enzyme preparations (such as proteases and lipases) are easily deactivated at high temperatures or high concentrations of bactericides, making it difficult to effectively remove sebum-based dirt (the main food source for mites) at low temperatures (20-30℃), indirectly affecting the anti-mite effect. Therefore, developing a laundry detergent that combines highly efficient broad-spectrum antibacterial and anti-mite properties, low-temperature stain removal, safety with low irritation, and anti-residue properties has become a pain point for the industry. Summary of the Invention

[0003] In view of the deficiencies of the prior art, the purpose of this invention is to provide an antibacterial and anti-mite laundry detergent based on lysozyme and BZK and its preparation method, so as to solve the problems mentioned in the background art.

[0004] The present invention solves the technical problem by adopting the following technical solution: This invention provides an antibacterial and anti-mite laundry detergent based on lysozyme and BZK, comprising the following raw materials by weight percentage: Lysozyme 0.01%~0.5%, BZK benzalkonium chloride 0.01%~1.0%, triclosan 0.02%~1.5%, chelating agent 0.01%~1.5%, compound surfactant 12%~35%, protease 0.01%~0.5%, lipase 0.01%~0.5%, modified cellulose derivative 0.05%~2.0%, pH adjuster 0.01%~1.5%, with the balance being deionized water.

[0005] Preferably, the chelating agent is EDTA-2Na and sodium citrate; The composite surfactant comprises 55% to 85% anionic surfactant and 15% to 45% nonionic surfactant; the anionic surfactant is sodium dodecylbenzenesulfonate or sodium salt of fatty alcohol polyoxyethylene ether; the nonionic surfactant is fatty alcohol polyoxyethylene ether or cocamide DEA; and the amphoteric surfactant is cocamidopropyl betaine, dodecyl betaine, or dodecyl hydroxysulfonyl betaine.

[0006] Preferably, the lysozyme has an enzyme activity of 2000 U / g to 50000 U / g, the protease is an alkaline protease with an enzyme activity of 50000 U / g to 200000 U / g, the lipase is an alkaline lipase with an enzyme activity of 50000 U / g to 200000 U / g, and the pH adjuster is prepared by mixing citric acid and sodium citrate in a weight ratio of 4:3 to 2:1.

[0007] Preferably, the method for preparing the modified cellulose derivative is as follows: S1: Add 3-5 parts of glass fiber and 2-3 parts of silicon carbide whiskers to 11-13 parts of sodium alginate solution with a mass fraction of 8%, then add 1-2 parts of silane coupling agent, stir evenly, and obtain the modified solution. S2: Add 4-7 parts of hydroxypropyl methylcellulose and 3-5 parts of montmorillonite to 8-11 parts of the modification solution and stir evenly. Then filter and dry to obtain the modified cellulose derivative.

[0008] Preferably, the silane coupling agent is silane coupling agent KH550.

[0009] Preferably, the preparation method of the montmorillonite agent is as follows: S11: Heat-treat montmorillonite at 210-230℃ for 1 hour, then cool it to 55℃ at a rate of 2-5℃ / min and hold it at that temperature; S12: The heat-insulating montmorillonite and the ball milling fluid are ball milled at a weight ratio of 7:5. The ball milling speed is 1000-1500 r / min and the ball milling time is 2 hours. After the ball milling is completed, the mixture is filtered and dried to obtain the montmorillonite agent. The ball milling slurry comprises the following raw materials in parts by weight: 2-5 parts silicon carbide, 3-5 parts nanocellulose, 1-3 parts β-cyclodextrin, and 5-8 parts ethanol solution.

[0010] The modified cellulose derivative uses hydroxypropyl methylcellulose as the matrix and is optimized by adding montmorillonite and a modifying liquid. The montmorillonite is improved by specific heat treatment and ball milling with a ball milling liquid composed of silicon carbide, nanocellulose, β-cyclodextrin and ethanol solution. At the same time, it is further improved and optimized with a specific modifying liquid. The resulting product raw material optimizes the antibacterial and antifungal properties of the product in the system.

[0011] Preferably, the ethanol solution has a mass fraction of 85-90%. This invention also provides a method for preparing an antibacterial and anti-mite laundry detergent based on lysozyme and BZK, comprising the following steps: (1) Pretreatment: Add deionized water to a reaction vessel equipped with stirring and temperature control, heat to 30~35℃, set the stirring speed to 200r / min, add chelating agent, and stir for 10min until completely dissolved; (2) Surfactant mixing: Add the composite surfactant to the solution obtained in step (1), increase the stirring speed to 300 r / min, stir for 20 min until a transparent solution is formed, and maintain the temperature at 30~35℃; (3) Addition of bactericidal ingredients: Triclosan is first pre-dissolved in ethanol solvent at 4-7 times the total amount of triclosan to obtain triclosan presolvent. Lysozyme and triclosan presolvent are added to the solution obtained in step (2) in sequence and stirred for 15 min. Then BZK is slowly added and stirred for another 10 min. (4) Addition of enzyme preparation and adjuvants: Reduce the temperature of the solution obtained in step (3) to 25~30℃, add protease and lipase, and stir for 10 min; then add modified cellulose derivative and stir for 15 min; (5) pH adjustment and volume adjustment: Add pH adjuster to the solution obtained in step (4) to adjust the pH of the system to 6.5~7.5 and stir for 5 min; finally add deionized water to the total mass and stir for 10 min until the system is homogeneous to obtain antibacterial and anti-mite laundry detergent. When adding lysozyme and triclosan presolvent in step (3), add them slowly while stirring, and the addition time is 5-8 minutes. Preferably, before adding protease and lipase in step (4), the enzyme preparation needs to be diluted with a small amount of deionized water to a solution with a mass concentration of 10% to 20%.

[0012] Compared with the prior art, the present invention has the following beneficial effects: This invention provides synergistic antibacterial and anti-mite effects with significant results: after lysozyme destroys the bacterial cell wall, BZK and triclosan rapidly kill residual microorganisms. It targets the surface of mites and has a 20-minute inhibition rate of ≥99.9% against Escherichia coli, Staphylococcus aureus, and Candida albicans, and a mite removal rate of ≥99.9%, solving the problem of limited effectiveness of single ingredients. Low-Temperature High-Efficiency Stain Removal: The compound surfactants (anionic + nonionic + amphoteric) maintain high activity at 20~30℃, and work with proteases / lipases to specifically break down sebum and dirt (food source for mites). Low-temperature stain removal power (30℃) is 40%~60% higher than traditional laundry detergents, achieving synergistic "stain removal + mite removal". Safe and Low-Irritation: The BZK concentration is controlled at 0.1%~0.3% (below the skin irritation threshold of 0.5%), and the amount of chemical bactericides used is reduced through lysozyme; the pH is 6.5~7.5, close to the slightly acidic environment of the skin, and human skin patch tests show an irritation score ≤0.5 (non-irritating), suitable for allergy sufferers. Excellent Residue Resistance: Modified cellulose derivatives reduce the adsorption of bactericides on the fabric surface through steric hindrance. After 3 washes, the residual amount on the fabric is ≤0.01mg / g, far lower than traditional laundry detergents (0.05~0.1mg / g), avoiding fabric stiffness and skin itching. Detailed Implementation

[0013] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to specific examples. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0014] In this embodiment, the following components are present: lysozyme 0.01%~0.5%, BZK benzalkonium chloride 0.01%~1.0%, triclosan 0.02%~1.5%, chelating agent 0.01%~1.5%, compound surfactant 12%~35%, protease 0.01%~0.5%, lipase 0.01%~0.5%, modified cellulose derivative 0.05%~2.0%, pH adjuster 0.01%~1.5%, and the balance being deionized water.

[0015] The chelating agents in this embodiment are EDTA-2Na and sodium citrate; The composite surfactant comprises 55% to 85% anionic surfactant and 15% to 45% nonionic surfactant; the anionic surfactant is sodium dodecylbenzenesulfonate or sodium salt of fatty alcohol polyoxyethylene ether; the nonionic surfactant is fatty alcohol polyoxyethylene ether or cocamide DEA; the amphoteric surfactant is cocamidopropyl betaine, dodecyl betaine, or dodecyl hydroxysulfonyl betaine.

[0016] In this embodiment, the lysozyme has an enzyme activity of 2000 U / g to 50000 U / g, the protease is an alkaline protease with an enzyme activity of 50000 U / g to 200000 U / g, the lipase is an alkaline lipase with an enzyme activity of 50000 U / g to 200000 U / g, and the pH adjuster is prepared by mixing citric acid and sodium citrate in a weight ratio of 4:3 to 2:1.

[0017] The preparation method of the modified cellulose derivative in this embodiment is as follows: S1: Add 3-5 parts of glass fiber and 2-3 parts of silicon carbide whiskers to 11-13 parts of sodium alginate solution with a mass fraction of 8%, then add 1-2 parts of silane coupling agent, stir evenly, and obtain the modified solution. S2: Add 4-7 parts of hydroxypropyl methylcellulose and 3-5 parts of montmorillonite to 8-11 parts of the modification solution and stir evenly. Then filter and dry to obtain the modified cellulose derivative.

[0018] The silane coupling agent in this embodiment is silane coupling agent KH550.

[0019] The preparation method of the montmorillonite agent in this embodiment is as follows: S11: Heat-treat montmorillonite at 210-230℃ for 1 hour, then cool it to 55℃ at a rate of 2-5℃ / min and hold it at that temperature; S12: The heat-insulating montmorillonite and the ball milling fluid are ball milled at a weight ratio of 7:5. The ball milling speed is 1000-1500 r / min and the ball milling time is 2 hours. After the ball milling is completed, the mixture is filtered and dried to obtain the montmorillonite agent. The ball milling slurry comprises the following raw materials in parts by weight: 2-5 parts silicon carbide, 3-5 parts nanocellulose, 1-3 parts β-cyclodextrin, and 5-8 parts ethanol solution.

[0020] The ethanol solution in this embodiment has a mass fraction of 85-90%. This embodiment describes a method for preparing an antibacterial and anti-mite laundry detergent based on lysozyme and BZK, comprising the following steps: (1) Pretreatment: Add deionized water to a reaction vessel equipped with stirring and temperature control, heat to 30~35℃, set the stirring speed to 200r / min, add chelating agent, and stir for 10min until completely dissolved; (2) Surfactant mixing: Add the composite surfactant to the solution obtained in step (1), increase the stirring speed to 300 r / min, stir for 20 min until a transparent solution is formed, and maintain the temperature at 30~35℃; (3) Addition of bactericidal ingredients: Triclosan is first pre-dissolved in ethanol solvent at 4-7 times the total amount of triclosan to obtain triclosan presolvent. Lysozyme and triclosan presolvent are added to the solution obtained in step (2) in sequence and stirred for 15 min. Then BZK is slowly added and stirred for another 10 min. (4) Addition of enzyme preparation and adjuvants: Reduce the temperature of the solution obtained in step (3) to 25~30℃, add protease and lipase, and stir for 10 min; then add modified cellulose derivative and stir for 15 min; (5) pH adjustment and volume adjustment: Add pH adjuster to the solution obtained in step (4) to adjust the pH of the system to 6.5~7.5 and stir for 5 min; finally add deionized water to the total mass and stir for 10 min until the system is homogeneous to obtain antibacterial and anti-mite laundry detergent. When adding lysozyme and triclosan presolvent in step (3), add them slowly while stirring, and the addition time is 5-8 minutes. Before adding protease and lipase in step (4) of this embodiment, the enzyme preparation needs to be diluted with a small amount of deionized water to a solution with a mass concentration of 10%~20%.

[0021] Example 1. In this embodiment, the following components are present: lysozyme 0.01%, BZK benzalkonium chloride 0.01%, triclosan 0.02%, chelating agent 0.01%, compound surfactant 12%, protease 0.01%, lipase 0.01%, modified cellulose derivative 0.05%, pH adjuster 0.01%, and the balance being deionized water.

[0022] The chelating agents in this embodiment are EDTA-2Na and sodium citrate; The composite surfactant comprises 55% anionic surfactant and 45% nonionic surfactant; the anionic surfactant is sodium dodecylbenzenesulfonate and sodium salt of fatty alcohol polyoxyethylene ether; the nonionic surfactant is fatty alcohol polyoxyethylene ether and cocamide DEA; and the amphoteric surfactant is cocamidopropyl betaine, dodecyl betaine, and dodecyl hydroxysulfonyl betaine.

[0023] In this embodiment, the lysozyme has an enzyme activity of 2000 U / g, the protease is an alkaline protease with an enzyme activity of 50000 U / g, the lipase is an alkaline lipase with an enzyme activity of 50000 U / g, and the pH adjuster is citric acid and sodium citrate prepared in a weight ratio of 4:3 to 2:1.

[0024] The preparation method of the modified cellulose derivative in this embodiment is as follows: S1: Add 3 parts glass fiber and 2 parts silicon carbide whiskers to 11 parts sodium alginate solution with a mass fraction of 8%, then add 1 part silane coupling agent, stir evenly to obtain modified solution; S2: Add 4 parts hydroxypropyl methylcellulose and 3 parts montmorillonite to 8 parts of the modification solution and stir evenly. Then filter and dry to obtain the modified cellulose derivative.

[0025] The silane coupling agent in this embodiment is silane coupling agent KH550.

[0026] The preparation method of the montmorillonite agent in this embodiment is as follows: S11: Heat-treat montmorillonite at 210℃ for 1 hour, then cool it to 55℃ at a rate of 2℃ / min and hold it at that temperature; S12: The heat-insulating montmorillonite and the ball milling fluid were ball milled at a weight ratio of 7:5, the ball milling speed was 1000 r / min, and the ball milling was carried out for 2 hours. After the ball milling was completed, the mixture was filtered and dried to obtain the montmorillonite agent. The ball milling slurry comprises the following raw materials in parts by weight: 2 parts silicon carbide, 3 parts nanocellulose, 1 part β-cyclodextrin, and 5 parts ethanol solution.

[0027] The ethanol solution in this embodiment has a mass fraction of 85%. This embodiment describes a method for preparing an antibacterial and anti-mite laundry detergent based on lysozyme and BZK, comprising the following steps: (1) Pretreatment: Add deionized water to a reaction vessel equipped with stirring and temperature control, heat to 30°C, set the stirring speed to 200 r / min, add chelating agent, and stir for 10 min until completely dissolved; (2) Surfactant mixing: Add the composite surfactant to the solution obtained in step (1), increase the stirring speed to 300 r / min, stir for 20 min until a transparent solution is formed, and maintain the temperature at 30℃; (3) Addition of bactericidal ingredients: Triclosan was first pre-dissolved in ethanol solvent with 4 times the total amount of triclosan to obtain triclosan presolvent. Lysozyme and triclosan presolvent were added to the solution obtained in step (2) in sequence and stirred for 15 min. Then BZK was slowly added and stirred for another 10 min. (4) Addition of enzyme preparation and adjuvants: Reduce the temperature of the solution obtained in step (3) to 25°C, add protease and lipase, and stir for 10 min; then add modified cellulose derivative and stir for 15 min; (5) pH adjustment and volume adjustment: Add pH adjuster to the solution obtained in step (4) to adjust the pH of the system to 6.5 and stir for 5 min; finally add deionized water to the total mass and stir for 10 min until the system is homogeneous to obtain antibacterial and anti-mite laundry detergent. In step (3) of this embodiment, when adding lysozyme and triclosan presolvent, the addition is carried out slowly while stirring, and the addition time is 5 minutes. Before adding protease and lipase in step (4) of this embodiment, the enzyme preparation needs to be diluted with a small amount of deionized water to a solution with a mass concentration of 10%.

[0028] Example 2. In this embodiment, the following components are present: lysozyme 0.5%, BZK benzalkonium chloride 1.0%, triclosan 1.5%, chelating agent 1.5%, compound surfactant 5%, protease 0.5%, lipase 0.5%, modified cellulose derivative 2.0%, pH adjuster 1.5%, and the balance being deionized water.

[0029] The chelating agents in this embodiment are EDTA-2Na and sodium citrate; The composite surfactant comprises 85% anionic surfactant and 15% nonionic surfactant; the anionic surfactant is sodium dodecylbenzenesulfonate and sodium salt of fatty alcohol polyoxyethylene ether; the nonionic surfactant is fatty alcohol polyoxyethylene ether and cocamide DEA; and the amphoteric surfactant is cocamidopropyl betaine, dodecyl betaine, and dodecyl hydroxysulfonyl betaine.

[0030] The enzyme has an activity of 50,000 U / g, the protease is an alkaline protease with an activity of 200,000 U / g, the lipase is an alkaline lipase with an activity of 200,000 U / g, and the pH adjuster is prepared by mixing citric acid and sodium citrate in a weight ratio of 4:3 to 2:1.

[0031] The preparation method of the modified cellulose derivative in this embodiment is as follows: S1: Add 5 parts glass fiber and 3 parts silicon carbide whiskers to 13 parts sodium alginate solution with a mass fraction of 8%, then add 2 parts silane coupling agent, stir evenly to obtain modified solution; S2: Add 7 parts hydroxypropyl methylcellulose and 5 parts montmorillonite to 11 parts of the modification solution and stir evenly. Then filter and dry to obtain the modified cellulose derivative.

[0032] The silane coupling agent in this embodiment is silane coupling agent KH550.

[0033] The preparation method of the montmorillonite agent in this embodiment is as follows: S11: Heat-treat montmorillonite at 230℃ for 1 hour, then cool it to 55℃ at a rate of 5℃ / min and hold it at that temperature; S12: The heat-insulating montmorillonite and the ball milling fluid are ball milled at a weight ratio of 7:5. The ball milling speed is 1500 r / min and the ball milling time is 2 h. After the ball milling is completed, the mixture is filtered and dried to obtain the montmorillonite agent. The ball milling slurry comprises the following raw materials in parts by weight: 5 parts silicon carbide, 5 parts nanocellulose, 3 parts β-cyclodextrin, and 8 parts ethanol solution.

[0034] The ethanol solution in this embodiment has a mass fraction of 90%. This embodiment describes a method for preparing an antibacterial and anti-mite laundry detergent based on lysozyme and BZK, comprising the following steps: (1) Pretreatment: Add deionized water to a reaction vessel equipped with stirring and temperature control, heat to 35°C, set the stirring speed to 200 r / min, add chelating agent, and stir for 10 min until completely dissolved; (2) Surfactant mixing: Add the composite surfactant to the solution obtained in step (1), increase the stirring speed to 300 r / min, stir for 20 min until a transparent solution is formed, and maintain the temperature at 35℃; (3) Addition of bactericidal ingredients: Triclosan was first pre-dissolved in ethanol solvent at 7 times the total amount of triclosan to obtain triclosan presolvent. Lysozyme and triclosan presolvent were added to the solution obtained in step (2) in sequence and stirred for 15 min. Then BZK was slowly added and stirred for another 10 min. (4) Addition of enzyme preparation and adjuvant: Reduce the temperature of the solution obtained in step (3) to 30°C, add protease and lipase, and stir for 10 min; then add modified cellulose derivative and stir for 15 min; (5) pH adjustment and volume adjustment: Add pH adjuster to the solution obtained in step (4) to adjust the pH of the system to 7.5 and stir for 5 min; finally add deionized water to the total mass and stir for 10 min until the system is homogeneous to obtain antibacterial and anti-mite laundry detergent. In step (3) of this embodiment, when adding lysozyme and triclosan presolvent, the addition is carried out slowly while stirring, and the addition time is 8 minutes. Before adding protease and lipase in step (4) of this embodiment, the enzyme preparation needs to be diluted with a small amount of deionized water to a solution with a mass concentration of 20%.

[0035] Example 3. In this embodiment, the following components are present: lysozyme 0.2%, BZK benzalkonium chloride 0.5%, triclosan 1.0%, chelating agent 0.7%, compound surfactant 20%, protease 0.3%, lipase 0.2%, modified cellulose derivative 1%, pH adjuster 1.0%, and the remainder is deionized water.

[0036] The chelating agents in this embodiment are EDTA-2Na and sodium citrate; The composite surfactant comprises 75% anionic surfactant and 25% nonionic surfactant; the anionic surfactant is sodium dodecylbenzenesulfonate and sodium salt of fatty alcohol polyoxyethylene ether; the nonionic surfactant is fatty alcohol polyoxyethylene ether and cocamide DEA; and the amphoteric surfactant is cocamidopropyl betaine, dodecyl betaine, and dodecyl hydroxysulfonyl betaine.

[0037] In this embodiment, the lysozyme has an enzyme activity of 30,000 U / g, the protease is an alkaline protease with an enzyme activity of 100,000 U / g, the lipase is an alkaline lipase with an enzyme activity of 100,000 U / g, and the pH adjuster is prepared by mixing citric acid and sodium citrate in a weight ratio of 4:3 to 2:1.

[0038] The preparation method of the modified cellulose derivative in this embodiment is as follows: S1: Add 4 parts of glass fiber and 2.5 parts of silicon carbide whiskers to 12 parts of sodium alginate solution with a mass fraction of 8%, then add 1.5 parts of silane coupling agent, stir evenly, and obtain the modified solution; S2: Add 5.5 parts of hydroxypropyl methylcellulose and 4 parts of montmorillonite to 10 parts of the modification solution and stir evenly. Then filter and dry to obtain the modified cellulose derivative.

[0039] The silane coupling agent in this embodiment is silane coupling agent KH550.

[0040] The preparation method of the montmorillonite agent in this embodiment is as follows: S11: The montmorillonite was heat-treated at 220℃ for 1 hour, then cooled to 55℃ at a rate of 3.5℃ / min and held at that temperature. S12: The heat-insulating montmorillonite and the ball milling fluid are ball milled at a weight ratio of 7:5. The ball milling speed is 1250 r / min and the ball milling time is 2 h. After the ball milling is completed, the mixture is filtered and dried to obtain the montmorillonite agent. The ball milling slurry comprises the following raw materials in parts by weight: 3.5 parts silicon carbide, 4 parts nanocellulose, 2 parts β-cyclodextrin, and 6.5 parts ethanol solution.

[0041] The ethanol solution in this embodiment has a mass fraction of 88%. This embodiment describes a method for preparing an antibacterial and anti-mite laundry detergent based on lysozyme and BZK, comprising the following steps: (1) Pretreatment: Add deionized water to a reaction vessel equipped with stirring and temperature control, heat to 32°C, set the stirring speed to 200 r / min, add chelating agent, and stir for 10 min until completely dissolved; (2) Surfactant mixing: Add the composite surfactant to the solution obtained in step (1), increase the stirring speed to 300 r / min, stir for 20 min until a transparent solution is formed, and maintain the temperature at 32℃; (3) Addition of bactericidal ingredients: Triclosan was first pre-dissolved in ethanol solvent at 5.5 times the total amount of triclosan to obtain triclosan presolvent. Lysozyme and triclosan presolvent were added to the solution obtained in step (2) in sequence and stirred for 15 min. Then BZK was slowly added and stirred for another 10 min. (4) Addition of enzyme preparation and adjuvants: Reduce the temperature of the solution obtained in step (3) to 28°C, add protease and lipase, and stir for 10 min; then add modified cellulose derivative and stir for 15 min; (5) pH adjustment and volume adjustment: Add pH adjuster to the solution obtained in step (4) to adjust the pH of the system to 6.7 and stir for 5 min; finally add deionized water to the total mass and stir for 10 min until the system is homogeneous to obtain antibacterial and anti-mite laundry detergent. In step (3) of this embodiment, lysozyme and triclosan presolvent are added slowly while stirring, and the addition time is 6.5 min. Before adding protease and lipase in step (4) of this embodiment, the enzyme preparation needs to be diluted with a small amount of deionized water to a solution with a mass concentration of 15%.

[0042] Comparative Example 1. Unlike Example 3, no modified cellulose derivatives were added.

[0043] Comparative Example 2. Unlike Example 3, no montmorillonite agent was added in the preparation of the modified cellulose derivative.

[0044] Comparative Example 3. Unlike Example 3, no ball milling fluid was added to the montmorillonite agent.

[0045] Comparative Example 4. Unlike Example 3, silicon carbide and nanocellulose were not added to the ball milling fluid.

[0046] Comparative Example 5. Unlike Example 3, no glass fiber or silicon carbide whiskers were added to the modification solution in the preparation of the modified cellulose derivative.

[0047] Performance tests of Examples 1-3 and Comparative Examples 1-5 were conducted, and the test results are as follows.

[0048]

[0049] As demonstrated in Examples 1-3, the product of the present invention significantly outperforms existing products in all aspects through the synergistic effect of the compound bactericidal formula, the low-temperature optimized stain removal system, strict safety control, and anti-residue design. Among these features, it achieves "double high" sterilization and mite removal rates, greatly improves low-temperature stain removal power, and takes into account both safety and low residue, fully meeting consumers' needs for efficient, mild, and environmentally friendly laundry detergent, and has significant market application value.

[0050]

[0051]

[0052] As can be seen from Comparative Examples 1-5, the performance of the product changes significantly when no modified cellulose derivatives are added. Furthermore, the performance of the product tends to deteriorate when montmorillonite is not added in the preparation of the modified cellulose derivatives, when ball milling fluid is not added to the montmorillonite, when silicon carbide and nanocellulose are not added to the ball milling fluid, or when glass fiber and silicon carbide whiskers are not added to the modification solution in the preparation of the modified cellulose derivatives. Only the product raw material obtained by the method of this invention has the most significant performance effect.

[0053] It will be apparent to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above, and that the invention can be implemented in other specific forms without departing from the spirit or essential characteristics of the invention. Therefore, the embodiments should be considered in all respects as exemplary and non-limiting, and the scope of the invention is defined by the appended claims rather than the foregoing description. Thus, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within the present invention.

[0054] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A bactericidal and mite-removing laundry detergent based on lysozyme and BZK, characterized in that, By weight percentage, it includes the following raw materials: Lysozyme 0.01%~0.5%, BZK benzalkonium chloride 0.01%~1.0%, triclosan 0.02%~1.5%, chelating agent 0.01%~1.5%, compound surfactant 12%~35%, protease 0.01%~0.5%, lipase 0.01%~0.5%, modified cellulose derivative 0.05%~2.0%, pH adjuster 0.01%~1.5%, with the balance being deionized water.

2. The laundry detergent according to claim 1, characterized in that, The chelating agents are EDTA-2Na and sodium citrate; The composite surfactant comprises 54% to 75% anionic surfactant and 15% to 45% nonionic surfactant; the amphoteric surfactant comprises 1% to 10%. The anionic surfactants are sodium dodecylbenzene sulfonate, sodium fatty alcohol polyoxyethylene ether, and sodium olefin sulfonate. The nonionic surfactants are fatty alcohol polyoxyethylene ether, cocamide DEA, and cocamide MEA. The amphoteric surfactants are cocamidopropyl betaine, dodecyl betaine, and dodecyl hydroxysulfonyl betaine.

3. The laundry detergent according to claim 1, characterized in that, The lysozyme has an enzyme activity of 2000 U / g to 50000 U / g, the protease is an alkaline protease with an enzyme activity of 50000 U / g to 200000 U / g, the lipase is an alkaline lipase with an enzyme activity of 50000 U / g to 200000 U / g, and the pH adjuster is prepared by mixing citric acid and sodium citrate in a weight ratio of 4:3 to 2:

1.

4. The laundry detergent according to claim 1, characterized in that, The method for preparing the modified cellulose derivative is as follows: S1: Add 3-5 parts of glass fiber and 2-3 parts of silicon carbide whiskers to 11-13 parts of sodium alginate solution with a mass fraction of 8%, then add 1-2 parts of silane coupling agent, stir evenly, and obtain the modified solution. S2: Add 4-7 parts of hydroxypropyl methylcellulose and 3-5 parts of montmorillonite to 8-11 parts of the modification solution and stir evenly. Then filter and dry to obtain the modified cellulose derivative.

5. The laundry detergent according to claim 1, characterized in that, The silane coupling agent is silane coupling agent KH550.

6. The laundry detergent according to claim 1, characterized in that, The preparation method of the montmorillonite agent is as follows: S11: Heat-treat montmorillonite at 210-230℃ for 1 hour, then cool it to 55℃ at a rate of 2-5℃ / min and hold it at that temperature; S12: The heat-insulating montmorillonite and the ball milling fluid are ball milled at a weight ratio of 7:

5. The ball milling speed is 1000-1500 r / min and the ball milling time is 2 hours. After the ball milling is completed, the mixture is filtered and dried to obtain the montmorillonite agent. The ball milling slurry comprises the following raw materials in parts by weight: 2-5 parts silicon carbide, 3-5 parts nanocellulose, 1-3 parts β-cyclodextrin, and 5-8 parts ethanol solution.

7. The laundry detergent according to claim 1, characterized in that, The ethanol solution has a mass fraction of 85-90%.

8. A method for preparing an antibacterial and anti-mite laundry detergent based on lysozyme and BZK as described in any one of claims 1-7, characterized in that, Includes the following steps: (1) Pretreatment: Add deionized water to a reaction vessel equipped with stirring and temperature control, heat to 30~35℃, set the stirring speed to 200r / min, add chelating agent, and stir for 10min until completely dissolved; (2) Surfactant mixing: Add the composite surfactant to the solution obtained in step (1), increase the stirring speed to 300 r / min, stir for 20 min until a transparent solution is formed, and maintain the temperature at 30~35℃; (3) Addition of bactericidal ingredients: Triclosan is first pre-dissolved in ethanol solvent at 4-7 times the total amount of triclosan to obtain triclosan presolvent. Lysozyme and triclosan presolvent are added to the solution obtained in step (2) in sequence and stirred for 15 min. Then BZK is slowly added and stirred for another 10 min. (4) Addition of enzyme preparation and adjuvants: Reduce the temperature of the solution obtained in step (3) to 25~30℃, add protease and lipase, and stir for 10 min; then add modified cellulose derivative and stir for 15 min; (5) pH adjustment and volume adjustment: Add pH adjuster to the solution obtained in step (4) to adjust the pH of the system to 6.5~7.5 and stir for 5 min; finally add deionized water to the total mass and stir for 10 min until the system is homogeneous to obtain antibacterial and anti-mite laundry detergent.

9. The preparation method according to claim 8, characterized in that, When adding lysozyme and triclosan presolvent in step (3), add them slowly while stirring, and the addition time is 5-8 minutes.

10. The preparation method according to claim 8, characterized in that, Before adding protease and lipase in step (4), the enzyme preparation needs to be diluted with a small amount of deionized water to a mass concentration of 10%~20%.

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