An intelligent early warning method and system for adverse reactions of chemotherapy drugs for tumor patients

By fusing patient gene sequencing data and temporal physiological indicators, and using a long short-term memory network model to identify potential subclinical neurological damage signals, the problem of early warning of irreversible neurological damage caused by chemotherapy was solved, and individualized and accurate risk prediction was achieved.

CN121812206BActive Publication Date: 2026-06-09FOURTH MILITARY MEDICAL UNIVERSITY
View PDF 1 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
FOURTH MILITARY MEDICAL UNIVERSITY
Filing Date
2026-03-10
Publication Date
2026-06-09

Smart Images

  • Figure CN121812206B_ABST
    Figure CN121812206B_ABST
Patent Text Reader

Abstract

The present application relates to the technical field of intelligent medical prediction, in particular to a kind of intelligent early warning method and system for adverse reactions of tumor patient chemotherapy drug, method includes: the gene sequencing data of current patient, time sequence physiological index data are input to network model, network model output damage stage;The training data set of network model includes: gene sequencing data, time sequence physiological index data and damage stage;The acquisition process of damage stage includes: based on gene sequencing data, the relative metabolic rate thereof to chemotherapy drug is acquired, and then the relative speed of its in-vivo toxicity accumulation is determined;After the time sequence physiological index data of meaningless physiological fluctuation of historical patient is smoothed, the nerve damage change curve is acquired according to time sequence physiological index data, and then whether there is potential subclinical signal segment in it is identified, if yes, then it is judged damage stage according to this.The present application can realize individualized, accurate risk prediction before irreversible nerve damage occurs caused by chemotherapy.
Need to check novelty before this filing date? Find Prior Art

Citation Information

Patent Citations

  • Tumor patient medication side effect management method and system based on big data analysis

    CN119446400A