Carbon nanodot-loaded anti-inflammatory and antibacterial hydrogel and preparation method and application thereof

By preparing a hydrogel composed of royal jelly carbon nanodots, esterified cassava starch, and yarrow gum, and combining it with honey, the problems of low bioavailability of royal jelly and poor adhesion of carbon nanodots were solved, achieving significant antibacterial, anti-inflammatory, and wound-healing effects, making it an alternative to antibiotics.

CN121944202APending Publication Date: 2026-05-01BEE RES INST CHINESE ACAD OF AGRI SCI
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Patent Information

Application Number
CN202512028081.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-12-30
Publication Date
2026-05-01

AI Technical Summary

Technical Problem

In existing technologies, royal jelly has low bioavailability, poor adhesion of carbon nanodots leads to poor efficacy, and antibiotics have side effects and drug resistance problems when treating bacterial wounds. There is a need to develop multifunctional active substances with no toxic side effects for wound healing.

Method used

By preparing a hydrogel composed of royal jelly carbon nanodots, esterified cassava starch, and yarrow gum, and combining it with honey, a composite hydrogel with good biocompatibility and gel properties is formed. The carbon nanodots are then loaded to enhance the antibacterial, anti-inflammatory, and wound-healing properties.

Benefits of technology

The antibacterial, anti-inflammatory, and antioxidant properties of royal jelly carbon nanodots have been significantly enhanced. The hydrogel has significant anti-inflammatory and wound-healing capabilities, making it an effective alternative to antibiotics for the treatment of bacterial wound infections.

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Abstract

The present application relates to the technical field of active material preparation, and particularly relates to an anti-inflammatory and antibacterial hydrogel loaded with carbon nanodots and a preparation method and application thereof. The hydrogel loaded with carbon nanodots provided by the present application contains royal jelly carbon nanodots; and the raw materials of the hydrogel contain the following components in parts by weight: 4-8 parts of honey, 10-15 parts of esterified cassava starch, and 1-3 parts of tragacanth. The hydrogel loaded with carbon nanodots provided by the present application combines royal jelly carbon nanodots and composite hydrogel, has good antibacterial, anti-inflammatory, antioxidant and wound healing effects, and has excellent biocompatibility and mechanical properties, and is expected to become an effective substitute for antibiotics, and is used for the treatment of bacterial infection wounds and has a good application prospect in the preparation of wound dressings.
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