An ice gelling comfrey soothing paste, and a preparation method and application thereof
By combining comfrey extract with other components, an ice-cooling comfrey soothing cream was prepared, which solves the problem that existing skin care products cannot immediately relieve itching and redness of sensitive skin, and achieves immediate soothing and long-lasting anti-itch effects.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- SHENZHEN HUAKUO BIOTECHNOLOGY CO LTD
- Filing Date
- 2026-04-10
- Publication Date
- 2026-05-29
AI Technical Summary
Existing skincare products are unlikely to effectively relieve itching and redness of sensitive skin in a short period of time, and drug-based anti-itch products need to be used according to doctor's prescription, which is difficult to meet the need for immediate relief.
A cooling comfrey soothing cream is prepared by combining comfrey extract, anti-allergy components, soothing components, cooling components, and moisturizing components. It achieves an immediate soothing effect by inhibiting inflammatory factors, lowering temperature, and increasing moisture.
It significantly reduces skin hemoglobin EI levels, lowers skin temperature, relieves skin discomfort, increases moisture, and provides immediate relief from itching and long-lasting soothing effects.
Smart Images
Figure CN122097220A_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of soothing cream technology, and in particular to a cooling comfrey soothing cream, its preparation method, and its application. Background Technology
[0002] With environmental changes, increased life stress, and changes in skincare practices, sensitive skin problems are becoming increasingly common. Dry skin, itching, and burning sensations are often interconnected. When the skin barrier function is impaired, the stratum corneum's ability to retain water decreases, leading to increased transepidermal water loss and causing dryness and flaking. At the same time, the dry environment stimulates nerve endings, producing itching, and the local inflammatory response further exacerbates vasodilation, resulting in burning and redness.
[0003] To address the aforementioned issues, existing technologies have developed various types of care products, primarily including the following categories: Simple moisturizing and repairing products, which use petrolatum, glycerin, urea, ceramides, etc., as main ingredients. These products have a relatively slow mechanism of action, typically requiring continuous use for several hours or even days to significantly improve symptoms, making them unsuitable for patients' immediate need for relief during acute flare-ups of itching; and pharmaceutical antipruritic products, such as topical corticosteroids, calcineurin inhibitors, or oral antihistamines. While these products are effective at relieving itching, they fall under the category of pharmaceuticals and must be used according to a doctor's prescription, and are not suitable for long-term or large-area use. For example, standard oral antihistamine treatment for urticaria typically takes at least one hour to take effect, failing to meet patients' urgent need for immediate relief.
[0004] Therefore, developing a soothing cream that can solve the above problems, achieve efficient and stable delivery of plant extracts, provide immediate cooling sensation and long-lasting itch relief, and has clear efficacy verification has become an urgent technical problem to be solved. Summary of the Invention
[0005] To address the aforementioned technical problems, this invention provides an ice-cooling comfrey soothing ointment, its preparation method, and its application.
[0006] To achieve this objective, the present invention adopts the following technical solution: In a first aspect, the present invention provides a cooling comfrey soothing cream, the cooling comfrey soothing cream comprising comfrey extract, anti-allergy components, soothing components, cooling components, moisturizing components and additives; The anti-allergic components include ectoine, Panax notoginseng root extract, Bletilla striata root extract, Bidens pilosa root extract, Rosa rugosa fruit extract, and Panax ginseng root extract.
[0007] Comfrey is a commonly used traditional Chinese medicine. Its extracts can significantly reduce the skin's EI value and lower temperature, providing a soothing effect. The anti-allergic components can inhibit inflammatory factors, thereby addressing the root cause of skin problems. The soothing components can effectively reduce skin sensitivity, decrease burning and stinging sensations, and relieve skin discomfort. The cooling components can promptly cool down red, swollen, and burning skin. The moisturizing components provide a suitable environment to relieve dryness and provide a material basis for repairing the skin barrier.
[0008] Preferably, the soothing components include Centella asiatica extract, Centella asiatica leaf extract, asiaticoside, asiaticoside and olive fruit extract.
[0009] In this invention, the extract of Centella asiatica is obtained from the whole plant, and the extract of Centella asiatica leaf is obtained from the leaves.
[0010] Preferably, the cooling component includes menthol and borneol.
[0011] Preferably, the moisturizing components include olive fruit oil and sunflower seed oil.
[0012] Preferably, the cooling comfrey soothing cream comprises, by weight, 0.000005-0.00003 parts of comfrey extract, 0.000086-0.00047 parts of anti-allergic component, 0.000175-0.00073 parts of soothing component, 1.1-6 parts of cooling component, 0.0001-0.0006 parts of moisturizing component, and 84.07231-115.93805 parts of excipients. The 0.000005-0.00003 parts can be, for example, 0.000005 parts, 0.00001 parts, 0.00002 parts, or 0.00003 parts, etc. The 0.000086-0.00047 parts can be, for example, 0.000086 parts, 0.0001 parts, 0.0002 parts, 0.0003 parts, 0.0004 parts, or 0.00047 parts, etc. The 0.000175-0.00073 parts can be, for example, 0.000175 parts, 0.0002 parts, 0.0003 parts, 0.0004 parts, 0.0005 parts, 0.0006 parts, 0.0007 parts, or 0.00073 parts, etc. The 1.1-6 parts can be, for example, 1.1 parts, 2 parts, 3 parts, 4 parts, 5 parts, or 6 parts, etc. The 0.0001-0.0006 parts can be, for example, 0.0001 parts, 0.0002 parts, 0.0003 parts, 0.0004 parts, 0.0005 parts, or 0.0006 parts, etc. The 84.07231-115.93805 parts can be, for example, 84.07231 parts, 85 parts, 90 parts, 95 parts, 100 parts, 105 parts, 110 parts, 115 parts, or 115.93805 parts, etc.
[0013] Preferably, the anti-allergic component comprises, by weight parts, 0.00005-0.0003 parts ectoine, 0.000005-0.00001 parts Panax notoginseng root extract, 0.00001-0.0001 parts Bletilla striata root extract, 0.00001-0.00005 parts Bidens pilosa root extract, 0.00001-0.00005 parts Rosa rugosa fruit extract, and 0.00001-0.00005 parts Panax ginseng root extract. The 0.00005-0.0003 parts can be, for example, 0.00005 parts, 0.0001 parts, 0.0002 parts, or 0.0003 parts, etc. The 0.000005-0.00001 parts can be, for example, 0.000005 parts, 0.000006 parts, 0.000007 parts, 0.000008 parts, 0.000009 parts, or 0.00001 parts, etc. The 0.00001-0.0001 parts can be, for example, 0.00001 parts, 0.00002 parts, 0.00004 parts, 0.00006 parts, 0.00007 parts, or 0.0001 parts, etc. The 0.00001-0.00005 parts can be, for example, 0.00001 parts, 0.00002 parts, 0.00003 parts, 0.00004 parts, or 0.00005 parts, etc.
[0014] Preferably, the soothing components, by weight, comprise 0.0001-0.0003 parts of Centella asiatica extract, 0.00001-0.00005 parts of Centella asiatica leaf extract, 0.00005-0.0003 parts of asiaticoside, 0.000005-0.00003 parts of asiaticoside, and 0.00001-0.00005 parts of olive fruit extract. The 0.0001-0.0003 parts can be, for example, 0.0001 parts, 0.0002 parts, or 0.0003 parts. The 0.00001-0.00005 parts can be, for example, 0.00001 parts, 0.00002 parts, 0.00003 parts, 0.00004 parts, or 0.00005 parts. The 0.00005-0.0003 parts can be, for example, 0.00005 parts, 0.0001 parts, 0.0002 parts, or 0.0003 parts.
[0015] Preferably, the cooling component comprises 1-5 parts menthol and 0.1-1 parts borneol by weight. The 1-5 parts can be, for example, 1 part, 2 parts, 3 parts, 4 parts, or 5 parts. The 0.1-1 part can be, for example, 0.1 part, 0.2 part, 0.4 part, 0.6 part, 0.8 part, or 1 part.
[0016] Preferably, the moisturizing component comprises, by weight, 0.00005-0.0003 parts olive fruit oil and 0.00005-0.0003 parts sunflower seed oil. The 0.00005-0.0003 parts can be, for example, 0.00005 parts, 0.0001 parts, 0.0002 parts, or 0.0003 parts, etc.
[0017] Preferably, the additives include any one or a combination of at least two of the following: solvents, humectants, thickeners, skin feel modifiers, emollients, skin protectants, cooling agents, preservatives, pH adjusters, or skin conditioning agents.
[0018] Preferably, the adjuvants, by weight, comprise any one or a combination of at least two of the following: 35-40 parts solvent, 41.3-54.9 parts humectant, 5-10 parts thickener, 1-3 parts skin feel modifier, 1-3 parts emollient, 0.06221-0.70705 parts skin protectant, 0.5-3 parts cooling agent, 0.1-1 part preservative, 0.1-0.3 parts pH adjuster, or 0.0101-0.031 parts skin conditioning agent. The 35-40 parts can be, for example, 35, 36, 37, 38, 39, or 40 parts. The 41.3-54.9 parts can be, for example, 41.3, 42, 44, 46, 48, 50, 52, 54, or 54.9 parts. The 5-10 portions can be, for example, 5, 6, 7, 8, 9, or 10 portions. The 1-3 portions can be, for example, 1, 2, or 3 portions. The 0.06221-0.70705 portions can be, for example, 0.06, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, or 0.70705 portions. The 0.5-3 portions can be, for example, 0.5, 1, 2, or 3 portions. The 0.1-1 portion can be, for example, 0.1, 0.2, 0.4, 0.6, 0.8, or 1 portion. The 0.1-0.3 portions can be, for example, 0.1, 0.2, or 0.3 portions. The 0.0101-0.031 parts can be, for example, 0.0101 parts, 0.2 parts, 0.3 parts, or 0.031 parts, etc.
[0019] Preferably, the solvent comprises 35-40 parts water. The 35-40 parts can be, for example, 35 parts, 36 parts, 37 parts, 38 parts, 39 parts, or 40 parts, etc.
[0020] Preferably, the moisturizer comprises any one or a combination of at least two of the following: 35-40 parts of 1,3-propanediol, 5-10 parts of glycerin, 1-4 parts of butylene glycol, 0.1-0.3 parts of caprylyl glycol, 0.1-0.3 parts of ethylhexylglycerin, and 0.1-0.3 parts of allantoin. The 35-40 parts can be, for example, 35, 36, 37, 38, 39, or 40 parts. The 5-10 parts can be, for example, 5, 6, 7, 8, 9, or 10 parts. The 1-4 parts can be, for example, 1, 2, 3, or 4 parts. The 0.1-0.3 parts can be, for example, 0.1, 0.2, or 0.3 parts.
[0021] Preferably, the thickener comprises 5-10 parts of sodium stearate. The 5-10 parts can be, for example, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, or 10 parts.
[0022] Preferably, the skin feel modifier comprises 1-3 parts of modified corn starch. The 1-3 parts can be, for example, 1 part, 2 parts, or 3 parts, etc.
[0023] Preferably, the emollient comprises 1-3 parts of bis-PEG-18 methyl ether dimethylsilane. The 1-3 parts can be, for example, 1 part, 2 parts, or 3 parts, etc.
[0024] Preferably, the skin protectant comprises any one or a combination of at least two of the following: 0.01-0.4 parts of Satsuma mandarin orange peel extract, 0.001-0.004 parts of Swertia japonica extract, 0.0001-0.001 parts of Gentiana macrophylla extract, 0.0001-0.001 parts of Gentiana scabra extract, 0.05-0.3 parts of dipotassium glycyrrhizate, 0.0005-0.001 parts of cyclodextrin, 0.00005-0.0001 parts of caprylic / capric triglyceride, and 0.00001-0.00005 parts of p-hydroxyacetophenone. The 0.01-0.4 parts can be, for example, 0.01 parts, 0.1 parts, 0.2 parts, 0.3 parts, or 0.4 parts. The 0.001-0.004 parts can be, for example, 0.001 parts, 0.002 parts, 0.003 parts, or 0.004 parts, etc. The 0.0001-0.001 parts can be, for example, 0.0001 parts, 0.0002 parts, 0.0004 parts, 0.0006 parts, 0.0008 parts, or 0.001 parts, etc. The 0.05-0.3 parts can be, for example, 0.05 parts, 0.1 parts, 0.2 parts, or 0.3 parts, etc. The 0.0005-0.001 parts can be, for example, 0.0005 parts, 0.0006 parts, 0.0008 parts, or 0.001 parts, etc. The 0.00001-0.00005 parts can be, for example, 0.00001 parts, 0.00002 parts, 0.00003 parts, 0.00004 parts, or 0.00005 parts, etc. The 0.00005-0.0001 parts can be, for example, 0.00005 parts, 0.00005 parts, 0.00006 parts, 0.00007 parts, 0.00008 parts, 0.00009 parts, or 0.0001 parts, etc.
[0025] Preferably, the cooling agent comprises 0.5-3 parts of menthone glycerol acetal. The 0.5-3 parts can be, for example, 0.5 parts, 1 part, 2 parts, or 3 parts, etc.
[0026] Preferably, the preservative comprises 0.1-1 parts of phenoxyethanol. The 0.1-1 parts can be, for example, 0.1 parts, 0.2 parts, 0.4 parts, 0.6 parts, 0.8 parts, or 1 part, etc.
[0027] Preferably, the pH adjuster comprises 0.1-0.3 parts of citric acid. The 0.1-0.3 parts may, for example, be 0.1 parts, 0.2 parts, or 0.3 parts, etc.
[0028] Preferably, the skin conditioning agent comprises 0.0001-0.001 parts of gardenia fruit extract, 0.01-0.03 parts of gardenia flower extract, or 0.001-0.01 parts of 1,2-hexanediol, or a combination of at least two of these. The 0.0001-0.001 parts can be, for example, 0.0001 parts, 0.0002 parts, 0.0004 parts, 0.0006 parts, 0.0008 parts, or 0.001 parts. The 0.01-0.03 parts can be, for example, 0.01 parts, 0.02 parts, or 0.03 parts. The 0.001-0.01 parts can be, for example, 0.001 parts, 0.002 parts, 0.004 parts, 0.006 parts, 0.008 parts, or 0.01 parts.
[0029] In a second aspect, the present invention provides a method for preparing the cooling comfrey soothing cream according to the first aspect, the method comprising mixing comfrey extract, anti-allergy component, soothing component, cooling component, moisturizing component and auxiliary agent.
[0030] Preferably, the preparation method includes mixing a solvent, a humectant, a thickener, a skin feel modifier, and a moisturizer, heating the mixture, cooling it down, and then adding comfrey extract, an anti-allergic component, a soothing component, a cooling component, a moisturizing component, a skin protectant, a cooling agent, a preservative, a pH adjuster, or a skin conditioning agent to the mixture.
[0031] Preferably, the temperature after heating is 85℃-95℃. The 85℃-95℃ can be, for example, 85℃, 87℃, 89℃, 91℃, 93℃, or 95℃.
[0032] Preferably, the temperature after cooling is 70℃-85℃. The 70℃-85℃ can be, for example, 70℃, 72℃, 74℃, 76℃, 78℃, 80℃, 82℃, 84℃, or 85℃, etc.
[0033] Compared with the prior art, the present invention has at least the following beneficial effects: This invention innovatively incorporates comfrey extract into the soothing cream, which can significantly reduce the skin's hemoglobin EI value and lower skin temperature. It also includes anti-allergic, cooling, soothing, and moisturizing components, achieving a four-pronged soothing effect by inhibiting inflammatory factors, lowering temperature, relieving skin discomfort, and increasing skin hydration. Attached Figure Description
[0034] Figure 1 The images shown are for TiVi700 using the soothing cream from Example 1. Image A is the detection image after the redness model was constructed, and image B is the detection image after 5 minutes of use. Detailed Implementation
[0035] The technical solution of the present invention will be further described below with reference to the accompanying drawings and specific embodiments. However, the following examples are merely simplified examples of the present invention and do not represent or limit the scope of protection of the present invention. The scope of protection of the present invention is determined by the claims.
[0036] The reagent sources used in the following examples are: Comfrey extract: Guangzhou Luojie Biotechnology Co., Ltd.; Ectocin: Bloomage Biotechnology (Tianjin) Co., Ltd.; Panax notoginseng root extract: Shanghai Jiakai Biotechnology Co., Ltd.; Bletilla striata root extract: Quzhou Zhanhong Biotechnology Co., Ltd.; Bidens pilosa root extract: Quzhou Zhanhong Biotechnology Co., Ltd.; Prickly pear fruit extract: Quzhou Zhanhong Biotechnology Co., Ltd.; Ginseng root extract: Quzhou Zhanhong Biotechnology Co., Ltd.; Centella asiatica extract: Shanghai Jiakai Biotechnology Co., Ltd.; Centella asiatica leaf extract: Quzhou Zhanhong Biotechnology Co., Ltd.; Hydroxyasiaticoside: Givaudan Fragrance & Flavor (Shanghai) Co., Ltd.; Centella asiatica extract: Quzhou Zhanhong Biotechnology Co., Ltd.; Olive fruit extract: Quzhou Zhanhong Biotechnology Co., Ltd.; Olive fruit oil: SOPHIM SAS; Sunflower seed oil: Northstar Lipids (UK) Ltd; Modified corn starch: Guangzhou Baifurun Chemical Co., Ltd.; Wenzhou mandarin orange peel extract: BioSpectrum, Inc.; Swamp ferns extract: Guangzhou Ganeng Biotechnology Co., Ltd.; Gentiana macrophylla extract: Guangzhou Gane Biotechnology Co., Ltd.; Gentian extract: Guangzhou Ganeng Biotechnology Co., Ltd.; Gardenia fruit extract: Shanghai Ruidean Biotechnology Co., Ltd.; Gardenia extract: BIOBEAUTECH CO., LTD.
[0037] Examples 1-3 Examples 1-3 describe the preparation of the soothing balm with cooling properties, and the specific formulas are shown in Table 1.
[0038] Table 1 The preparation method of the soothing balm with comfrey is as follows: The solvent, humectant, thickener, skin feel modifier, and emollient are homogenized and mixed, then heated to 90°C. After cooling to 80°C, comfrey extract, anti-allergy components, soothing components, cooling components, moisturizing components, skin protectants, cooling agents, preservatives, pH adjusters, or skin conditioning agents are added and mixed to obtain the final product.
[0039] Example 4 This embodiment prepares a soothing cream with a cooling sensation, which differs from Example 1 only in that it does not include Centella asiatica leaf extract, and the weight proportions of Centella asiatica leaf extract are added to Centella asiatica extract, hydroxyascorbic acid, asiaticoside and olive fruit extract according to the proportions in Example 1. The rest is the same as in Example 1.
[0040] Example 5 This embodiment prepares a cooling comfrey soothing ointment, which differs from Example 1 only in that olive fruit extract is not added, and the weight proportions of asiaticus leaf extract are added to asiaticus extract, asiaticus leaf extract, asiaticoside and asiaticoside according to the proportions in Example 1. The rest is the same as in Example 1.
[0041] Example 6 The preparation of the icy comfrey soothing ointment in this embodiment differs from that in Example 1 only in that menthol is not added, and the weight proportion of menthol is added to the borneol; otherwise, it is the same as in Example 1.
[0042] Example 7 The preparation of the Cooling Purple Grass Soothing Ointment in this embodiment differs from that in Example 1 only in that olive fruit oil is not added, and the weight proportions of olive fruit oil are added to sunflower seed oil. Otherwise, it is the same as that in Example 1.
[0043] Example 8 The preparation of the cooling comfrey soothing cream in this embodiment differs from that in Example 1 only in the amount of each component added: 0.00001 parts of comfrey extract, 0.0006 parts of anti-allergy component, 0.0001 parts of soothing component, 8 parts of cooling component, and 0.0009 parts of moisturizing component. The raw materials in each component are in the same proportion as in Example 1, and the rest are the same as in Example 1.
[0044] Example 9 This embodiment prepares a cooling comfrey soothing cream, which differs from Example 1 only in the amount of each component added: 0.0005 parts comfrey extract, 0.00005 parts anti-allergy component, 0.0005 parts soothing component, 0.5 parts cooling component, and 0.00005 parts moisturizing component. The raw materials in each component are in the same proportion as in Example 1, and the rest are the same as in Example 1.
[0045] Comparative Example 1 The comparative preparation of the icy comfrey soothing ointment differs from Example 1 only in that ectoine is not added, and the weight proportions of ectoine are added to Panax notoginseng root extract, Bletilla striata root extract, Bidens pilosa root extract, Rosa rugosa fruit extract and Panax ginseng root extract according to the proportions in Example 1. All other aspects are the same as in Example 1.
[0046] Comparative Example 2 The comparative preparation of the icy comfrey soothing ointment differs from Example 1 only in that it does not include Panax notoginseng root extract, and the weight proportions of Panax notoginseng root extract are added to ectoine, Bletilla striata root extract, Bidens pilosa root extract, Rosa rugosa fruit extract and ginseng root extract according to the proportions in Example 1. All other aspects are the same as in Example 1.
[0047] Comparative Example 3 The comparative preparation of the soothing balm with icy feeling is different from that of Example 1 only in that Bletilla striata root extract is not added, and the weight parts of Bletilla striata root extract are added to ectoine, Panax notoginseng root extract, Bidens pilosa root extract, Rosa rugosa fruit extract and ginseng root extract according to the proportions of Example 1. The rest is the same as that of Example 1.
[0048] Comparative Example 4 The comparative preparation of the soothing balm with cooling properties differs from Example 1 only in that it does not include Bidens trifoliata root extract, and the weight proportions of Bidens trifoliata root extract are added to Ectoin, Panax notoginseng root extract, Bletilla striata root extract, Rosa rugosa fruit extract and Panax ginseng root extract according to the proportions in Example 1. All other aspects are the same as in Example 1.
[0049] Comparative Example 5 The comparative preparation of the soothing balm with cooling properties differs from Example 1 only in that it does not include prickly pear fruit extract, and the weight proportions of prickly pear fruit extract are added to ectoine, Panax notoginseng root extract, Bletilla striata root extract, Bidens pilosa root extract and ginseng root extract according to the proportions in Example 1. All other aspects are the same as in Example 1.
[0050] Comparative Example 6 The comparative preparation of the icy comfrey soothing ointment differs from Example 1 only in that ginseng root extract is not added, and the weight proportions of ginseng root extract are added to ectoine, Panax notoginseng root extract, Bletilla striata root extract, Bidens pilosa root extract and Rosa rugosa fruit extract according to the proportions in Example 1. All other aspects are the same as in Example 1.
[0051] Comparative Example 7 The comparative example of preparing the icy comfrey soothing cream differs from Example 1 only in that it does not contain any anti-allergic components; otherwise, it is identical to Example 1.
[0052] Comparative Example 8 The comparative example of preparing the icy comfrey soothing cream differs from Example 1 only in that no soothing components are added; otherwise, it is identical to Example 1.
[0053] Comparative Example 9 The comparative example of preparing the cooling comfrey soothing balm differs from Example 1 only in that no cooling component is added; otherwise, it is identical to Example 1.
[0054] Comparative Example 10 The comparative example of preparing the icy comfrey soothing cream differs from Example 1 only in that no moisturizing components are added; otherwise, it is identical to Example 1.
[0055] Test Example 1 This test case examines the effectiveness of the cooling comfrey soothing balm. This test case measured the EI value of skin hemoglobin in 30 sensitive skin subjects before and after using the test sample, analyzed skin surface temperature and skin Tivi value, and conducted self-assessment by the subjects to verify the efficacy of the prepared anti-allergy and soothing floral water in soothing and reducing skin surface temperature.
[0056] This test recruited 33 volunteers, with 3 failing to complete the test, resulting in 30 valid participants for data analysis. All selected volunteers had sensitive skin prone to tightness, dryness, itching, redness, and sensitivity, and their ages ranged from 19 to 59 years.
[0057] Before sample use: Subjects cleaned their arms and dried their skin with a tissue, then sat quietly for 30 minutes in a laboratory at 21°C and 50% humidity. Laboratory technicians selected two 3 cm × 3 cm areas on the inner forearm and used an infrared therapy device with a 150 W bulb approximately 15 cm away from the arm to uniformly irradiate for 5 minutes to create a reddening model. Laboratory technicians used an RM Series Handheld Thermal Camera and a TiVi700 to acquire images of the subjects' arms and tested the baseline EI value of the subjects' skin hemoglobin. The floral water prepared in the above examples and comparative examples was applied at a dosage of 2.0 mg / cm². 2 The control group did not use any items, and the tests were conducted after 5 minutes. The specific results are shown in Table 2.
[0058] Table 2 The results above show that: After using Example 1, the skin hemoglobin EI value of the sensitive skin volunteers treated with the anti-allergy soothing floral water prepared according to this invention showed significantly better improvement than that of the control group. The skin hemoglobin EI value of Example 1 decreased significantly by 20.68%, while the skin hemoglobin EI value of the control group decreased significantly by 7.64%, showing a highly significant difference between the two groups. For volunteer No. 20, after applying the soothing cream of Example 1, images of the subject's arm were acquired using a TiVi700 before using Example 1, after constructing the redness model (T0), and 5 minutes after using Example 1 (T5 min). Specifically, as follows... Figure 1 As shown, the redness area was significantly improved 5 minutes after applying the soothing cream prepared in Example 1. This indicates that the anti-allergic soothing floral water prepared in this invention has a soothing effect 5 minutes after application.
[0059] Test Example 2 This test case involves self-assessment by volunteers. (1) Test of skin cooling sensation and anti-itch effect In this test case, before using Example 1, after constructing the redness model (T0), a questionnaire survey was conducted at 58 seconds (T58 s) and 5 minutes (T5 min) after using Example 1. Two questions were asked: Question 1: How do you rate your current skin cooling sensation (on a 9-point scale, 1 point indicates significant cooling sensation, and 9 points indicate no cooling sensation); Question 2: How do you rate your current dryness and itching sensation (on a 9-point scale, 1 point indicates mild, and 9 points indicate severe). The survey results are shown in Table 3.
[0060] Table 3 The results above show that the floral water prepared using this invention can significantly enhance the cooling sensation on the skin.
[0061] (2) Testing the effectiveness of use In this test case, a questionnaire survey was conducted at 58 seconds (T58 seconds) after using Example 1 and at 5 minutes (T5 minutes) after using Example 1. The specific results are shown in Table 4. The volunteers had a high degree of recognition for the toilet water prepared by this invention and were quite satisfied with its quality.
[0062] Table 4 In summary, this invention innovatively incorporates comfrey extract into the soothing cream, which can significantly reduce the skin's hemoglobin EI value and lower skin temperature. Furthermore, the addition of anti-allergic, cooling, soothing, and moisturizing components achieves a four-fold soothing effect by inhibiting inflammatory factors, lowering temperature, relieving skin discomfort, and increasing skin hydration.
[0063] The applicant declares that the above description is only a specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Those skilled in the art should understand that any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in the present invention fall within the protection and disclosure scope of the present invention.
Claims
1. A cooling comfrey soothing balm, characterized in that, The cooling comfrey soothing cream includes comfrey extract, anti-allergy components, soothing components, cooling components, moisturizing components, and additives. The anti-allergic components include ectoine, Panax notoginseng root extract, Bletilla striata root extract, Bidens pilosa root extract, Rosa rugosa fruit extract, and Panax ginseng root extract.
2. The soothing balm with cooling properties according to claim 1, characterized in that, The soothing components include Centella asiatica extract, Centella asiatica leaf extract, asiaticoside, asiaticoside and olive fruit extract; Preferably, the cooling component includes menthol and borneol; Preferably, the moisturizing components include olive fruit oil and sunflower seed oil.
3. The soothing balm with cooling properties according to claim 1 or 2, characterized in that, The cooling comfrey soothing cream comprises, by weight, 0.000005-0.00003 parts comfrey extract, 0.000086-0.00047 parts anti-allergy component, 0.000175-0.00073 parts soothing component, 1.1-6 parts cooling component, 0.0001-0.0006 parts moisturizing component, and 84.07231-115.93805 parts excipients; Preferably, the anti-allergic component comprises, by weight, 0.00005-0.0003 parts ectoine, 0.000005-0.00001 parts Panax notoginseng root extract, 0.00001-0.0001 parts Bletilla striata root extract, 0.00001-0.00005 parts Bidens pilosa root extract, 0.00001-0.00005 parts Rosa rugosa fruit extract, and 0.00001-0.00005 parts Panax ginseng root extract; Preferably, the soothing components, by weight, comprise 0.0001-0.0003 parts of Centella asiatica extract, 0.00001-0.00005 parts of Centella asiatica leaf extract, 0.00005-0.0003 parts of asiaticoside, 0.000005-0.00003 parts of asiaticoside and 0.00001-0.00005 parts of olive fruit extract; Preferably, the cooling component comprises 1-5 parts by weight of menthol and 0.1-1 parts by weight of borneol; Preferably, the moisturizing components include 0.00005-0.0003 parts by weight of olive fruit oil and 0.00005-0.0003 parts by weight of sunflower seed oil.
4. The soothing balm with comfrey root extract according to any one of claims 1-3, characterized in that, The additives include any one or a combination of at least two of the following: solvents, humectants, thickeners, skin feel modifiers, emollients, skin protectants, cooling agents, preservatives, pH adjusters, or skin conditioning agents.
5. The soothing balm with cooling properties according to claim 4, characterized in that, The adjuvants, by weight, include any one or a combination of at least two of the following: 35-40 parts solvent, 41.3-54.9 parts humectant, 5-10 parts thickener, 1-3 parts skin feel modifier, 1-3 parts emollient, 0.06221-0.70705 parts skin protectant, 0.5-3 parts cooling agent, 0.1-1 part preservative, 0.1-0.3 parts pH adjuster, or 0.0101-0.031 parts skin conditioning agent.
6. Preferably, the solvent comprises 35-40 parts water; Preferably, the moisturizer comprises any one or a combination of at least two of the following: 35-40 parts of 1,3-propanediol, 5-10 parts of glycerin, 1-4 parts of butylene glycol, 0.1-0.3 parts of caprylyl glycol, 0.1-0.3 parts of ethylhexylglycerin, and 0.1-0.3 parts of allantoin.
7. The soothing balm with cooling properties according to claim 4 or 5, characterized in that, The thickener comprises 5-10 parts of sodium stearate; Preferably, the skin feel modifier comprises 1-3 parts modified corn starch; Preferably, the emollient comprises 1-3 parts of bis-PEG-18 methyl ether dimethylsilane; Preferably, the skin protectant comprises any one or a combination of at least two of the following: 0.01-0.4 parts of Wenzhou mandarin orange peel extract, 0.001-0.004 parts of swertia spp. extract, 0.0001-0.001 parts of gentian root extract, 0.0001-0.001 parts of gentian root extract, 0.05-0.3 parts of dipotassium glycyrrhizate, 0.0005-0.001 parts of cyclodextrin, 0.00005-0.0001 parts of caprylic / capric triglyceride, and 0.00001-0.00005 parts of p-hydroxyacetophenone.
8. The soothing balm with comfrey root extract according to any one of claims 4-6, characterized in that, The cooling agent comprises 0.5-3 parts of menthone glycerol ketal; Preferably, the preservative comprises 0.1-1 parts phenoxyethanol; Preferably, the pH adjuster comprises 0.1-0.3 parts citric acid; Preferably, the skin conditioning agent comprises any one or a combination of at least two of the following: 0.0001-0.001 parts of gardenia fruit extract, 0.01-0.03 parts of gardenia flower extract, or 0.001-0.01 parts of 1,2-hexanediol.
9. The method for preparing the soothing balm with comfrey root according to any one of claims 1-7, characterized in that, The preparation method includes mixing comfrey extract, anti-allergy component, soothing component, cooling component, moisturizing component and auxiliary agent.
10. The preparation method of the soothing balm with cooling properties according to claim 8, characterized in that, The preparation method includes mixing a solvent, a moisturizer, a thickener, a skin feel modifier, and a skin emollient, heating the mixture, cooling it down, and then adding comfrey extract, an anti-allergic component, a soothing component, a cooling component, a moisturizing component, a skin protectant, a cooling agent, a preservative, a pH adjuster, or a skin conditioning agent to obtain the final product.
11. The preparation method of the soothing balm with cooling properties according to claim 9, characterized in that, The temperature after heating is 85℃-95℃; Preferably, the temperature after cooling is 70℃-85℃.