A traditional Chinese medicine composition for coronary heart disease

The "treating phlegm and blood stasis simultaneously and promoting multi-dimensional circulation" system, composed of traditional Chinese medicine ingredients such as Astragalus membranaceus and Polygonatum sibiricum, has solved the problems of limited efficacy and safety in the treatment of coronary heart disease. It has achieved significant effects in stabilizing atherosclerotic plaques, regulating lipid metabolism, and protecting vascular endothelial function, and has the advantage of protecting the liver.

CN122398948APending Publication Date: 2026-07-17THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV
Filing Date
2026-06-01
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing treatment options for coronary heart disease have limited efficacy, conventional drugs have adverse reactions and safety issues with long-term use, and the advantages of traditional Chinese medicine in treating coronary heart disease have not been fully utilized.

Method used

This invention provides a traditional Chinese medicine composition consisting of Astragalus membranaceus, Polygonatum sibiricum, Achyranthes bidentata, Ilex pubescens, Dioscorea nipponica, Gynostemma pentaphyllum, Polygonum multiflorum, Foeniculum vulgare, Polygonatum odoratum, and Luffa cylindrica. It follows the principle of "treating phlegm and blood stasis simultaneously and promoting multidimensional circulation" in its formulation. By carefully selecting raw materials and determining their proportions, it constructs a multidimensional circulation-promoting treatment system to resolve phlegm and blood stasis, and to replenish deficiency and lower lipids to strengthen the body's foundation.

Benefits of technology

It significantly stabilizes atherosclerotic plaques, regulates lipid metabolism disorders, protects vascular endothelial function, improves microcirculation, slows the progression of atherosclerotic lesions, has a clear hepatoprotective effect, improves medication safety, and is superior to traditional Western medicines.

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Abstract

本发明提供了一种用于冠心病的中药组合物,涉及中药技术领域。本发明采用红芪、黄精、夏天无、毛冬青、穿山龙、水茴香、玉竹、夜交藤、绞股蓝、丝瓜络为中药原料组成的组合物;以“气痉同治、痰瘀同源”法则,红芪补气增强血液运行,夏天无解痉改善血管顺应性,佐以毛冬青等中药扩张大血管、丝瓜络疏通微循环,实现“大血管‑痉挛血管‑微血管”三层通络;配伍水茴香等中药化痰药以清脉道,消瘀结以融斑块;全方兼具益气养阴、活血解痉、化痰通络之功;动物实验结果表明,本中药组合物可显著抑制氧化应激与黏附因子水平,调节血脂,减小主动脉斑块面积,从而有效延缓冠心病进展。
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