Immunogenic compositions comprising conjugated capsular saccharide antigens, kits and uses thereof

By developing immunogenic compositions containing glycoconjugates of multiple Streptococcus pneumoniae serotypes, the problems of insufficient protection against serotypes not covered by existing vaccines and antigen interference have been solved, achieving a balance between broad protection and immune response, and improving the protective effect of vaccines.

CN122399004APending Publication Date: 2026-07-17PFIZER INC
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
PFIZER INC
Filing Date
2016-07-18
Publication Date
2026-07-17

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Abstract

本发明涉及包含缀合的荚膜糖抗原的免疫原性组合物及其试剂盒和用途。具体而言，本发明涉及新的免疫原性组合物，其包括缀合的肺炎链球菌荚膜糖抗原(糖缀合物)、包括所述免疫原性组合物的试剂盒及其用途。本发明的免疫原性组合物将通常包括至少一种来自PREVNAR®、SYNFLORIX®和 / 或PREVNAR13®中未发现的肺炎链球菌血清型的糖缀合物。本发明还涉及使用所述新型免疫原性组合物对人类对象，特别是婴儿和老年人进行疫苗接种以抵抗肺炎球菌感染。
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Citation Information

Patent Citations

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