High-performance degradable biomedical tissue adhesive and preparation method and application thereof
A high-performance biodegradable biomedical tissue adhesive was prepared by linking PPDO with PEG and introducing succinimide ester groups. This method overcomes the shortcomings of existing adhesives in terms of biocompatibility and degradation safety, and achieves strong adhesion, controllable degradation and good biocompatibility.
Patent Information
- Application Number
- CN202610832044.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-06-10
- Publication Date
- 2026-07-17
AI Technical Summary
Existing medical tissue adhesives are insufficient in terms of biocompatibility and degradation safety, and cannot simultaneously achieve strong adhesion, controllable degradation and good biocompatibility.
By linking poly(p-dioxide) with hydrophilic polymers such as PEG and introducing succinimide ester groups on the side chains to form covalent bonds for strong adhesion, a high-performance biodegradable biomedical tissue adhesive is prepared by combining the crystallinity of PPDO and the flexibility of PEG.
It achieves high-strength, controllable degradability adhesives with elastic modulus and flexibility that match tissues, can rapidly degrade under physiological conditions, reduce stress and pressure, and provide strong adhesion and good biocompatibility.
Smart Images
Figure CN122399086A_ABST