Heparin sodium extraction and inactivation device

Abstract

The utility model discloses a heparin sodium extraction inactivation device, relates to the heparin sodium extraction technical field, including inactivation mechanism, tube cover mechanism, cleaning mechanism and other parts, the tube cover mechanism includes input tube, the upper port of input tube is provided with cover groove, the lateral side of cover groove is provided with four card slot in rectangular shape on the cover groove side, and the card slot is connected with the card slot. When an upper cover of the pipe cover mechanism of the device is disassembled, four clamping pieces can be moved out of clamping grooves only by rotating a knob through an assembly, then fixation of the upper cover can be relieved, and therefore disassembly of the upper cover becomes simple, workers can assemble and disassemble the upper cover conveniently, and then heparin sodium raw materials can be put in conveniently; after raw materials are discharged after inactivation, water in the water tank is pumped out through the water pump and fed into the annular pipe, all the nozzles are sprayed to the inner wall of the inactivation tank, and the water continuously washes the inner wall of the inactivation tank, so that the inner wall of the inactivation tank is cleaned, manual cleaning by workers is not needed, meanwhile, the water consumption for cleaning is low, and water is saved.

Description

Technical Field

[0001] The utility model relates to the technical field of sodium heparin extraction, in particular to a sodium heparin extraction and inactivation device. Background Art

[0002] Heparin sodium is the first anticoagulant discovered and isolated for medical use. More than a hundred years have passed since its discovery. It is one of the oldest drugs still used in clinical practice. So far, no synthetic product can completely replace it. It is still the most important anticoagulant and antithrombotic drug. It can only be extracted from animal tissues. Heparin sodium can prevent and treat arterial and venous thrombosis and pulmonary embolism. It can be used as an anticoagulant in artificial heart and lung, peritoneal dialysis or hemodialysis treatment. In recent years, studies have shown that heparin sodium also has the effects of lowering blood lipids, anti-cancer, anti-virus, anti-inflammatory, anti-allergic, anti-media smooth muscle cell hyperplasia, and reducing blood viscosity.

[0003] During the extraction process of sodium heparin, the raw materials need to be inactivated, so an inactivation device is needed. For example, the patent website discloses a biological vaccine inactivation device (publication number: CN220183239U). This device can also inactivate the sodium heparin raw materials. Multiple card boards in the device are inserted into the interior of the rectangular groove to fix the top cover. However, the number of card boards is large, so the top cover needs to be disassembled by releasing the card boards one by one, so the disassembly and installation operation steps are many and time-consuming. Therefore, a person skilled in the art has proposed a sodium heparin extraction and inactivation device. Utility Model Content

[0004] In view of the deficiencies in the prior art, the utility model provides a sodium heparin extraction and inactivation device. The tube cover mechanism of the device can release the fixation of the upper cover by rotating a knob, making the disassembly of the upper cover simple and solving the problem of difficult assembly and disassembly of the top cover in the above background.

[0005] To achieve the above purpose, the utility model is implemented through the following technical scheme: a heparin sodium extraction and inactivation device, comprising:

[0006] An inactivation mechanism, which is used to inactivate the heparin sodium raw material;

[0007] A tube cover mechanism, which is the input end of the device;

[0008] The tube cover mechanism comprises an input tube, an upper port of the input tube is provided with a cover groove, a side surface of the cover groove is provided with four slots in a rectangular shape on one side of the cover groove, an upper cover matched therewith is arranged in the cover groove, a cavity is arranged in the interior of the upper cover on one side of each slot, a limit plate is arranged in each cavity, a spring is arranged in one side of the limit plate in each cavity, a clamp extending into the aligned slot is installed at the center of the other side surface of each limit plate, a central groove is provided in the inner center of the upper cover, a winding rod is rotatably installed in the central groove, a pull rope whose end extends into the central groove and is fixedly connected to the winding rod is installed at the center of the side surface of each limit plate, and the end of the winding rod extends to the outside of the upper cover and is installed with a knob;

[0009] A cleaning mechanism is used for cleaning the inner wall of the device.

[0010] As a further technical solution of the utility model, the inactivation mechanism includes an inactivation tank installed at the lower end of the input pipe, and an input port is opened on the upper surface of the inactivation tank just below the input pipe.

[0011] As a further technical solution of the utility model, a motor is installed at the center of the upper surface of the inactivation tank, the driving end of the motor extends into the inactivation tank and is installed with a shaft, and a plurality of evenly distributed stirring blades are installed on the surface of the shaft.

[0012] As a further technical solution of the utility model, the cleaning mechanism includes an annular tube installed at the center of the top surface of the inactivation tank, and a plurality of nozzles evenly distributed and inclined toward the inner wall of the inactivation tank are installed on the side of the annular tube.

[0013] As a further technical solution of the utility model, a water pump whose output end is connected to the annular pipe is installed on the upper surface of the inactivation tank at one side of the motor, and a connecting pipe is installed at the input end of the water pump. Beneficial Effects

[0014] The utility model provides a heparin sodium extraction and inactivation device. Compared with the prior art, it has the following beneficial effects:

[0015] 1. A sodium heparin extraction and inactivation device. When disassembling the upper cover of the tube cover mechanism of the device, only the knob needs to be turned through the assembly to move four clamps out of the card slots, and then the upper cover can be released from the fixation, so that the disassembly of the upper cover becomes simple, which is convenient for the staff to load and unload the upper cover, and then it is convenient to put in the sodium heparin raw material.

[0016] 2. A sodium heparin extraction and inactivation device. The device is also provided with a cleaning mechanism. After the raw materials are discharged after inactivation, the water in the water tank is pumped out by a water pump and sent into the annular pipe so that each nozzle sprays the inner wall of the inactivation tank, so that the water continuously flushes the inner wall of the inactivation tank, thereby cleaning the inner wall. Manual cleaning is not required by staff, which reduces the amount of pulling by staff. At the same time, less water is used for cleaning, saving water. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a structural schematic diagram of a heparin sodium extraction and inactivation device;

[0018] Figure 2 It is a cross-sectional view of a heparin sodium extraction and inactivation device;

[0019] Figure 3 for Figure 2 Enlarged view of part A;

[0020] Figure 4 This is a disassembled diagram of the tube cover mechanism of a heparin sodium extraction and inactivation device;

[0021] Figure 5 The present invention is a cross-sectional view of the upper cover of a sodium heparin extraction and inactivation device.

[0022] In the figure: 1. inactivation tank; 2. input pipe; 3. cover groove; 4. card slot; 5. upper cover; 6. cavity; 7. limit plate; 8. spring; 9. card; 10. center groove; 11. winding rod; 12. pull rope; 13. knob; 14. input port; 15. motor; 16. shaft; 17. stirring blade; 18. ring tube; 19. nozzle; 20. water pump; 21. connecting pipe; 22. valve. DETAILED DESCRIPTION

[0023] The present disclosure is further described in detail below in conjunction with the accompanying drawings and implementations. It is understood that the specific implementations described herein are only used to explain the relevant content, rather than to limit the present disclosure. It should also be noted that, for ease of description, only the parts related to the present disclosure are shown in the accompanying drawings.

[0024] It should be noted that, in the absence of conflict, the embodiments and features of the embodiments in the present disclosure can be combined with each other. The technical solution of the present disclosure will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.

[0025] Unless otherwise specified, the exemplary embodiments / embodiments shown will be understood as providing exemplary features of various details of some ways in which the technical concept of the present disclosure can be implemented in practice. Therefore, unless otherwise specified, the features of the various embodiments / embodiments can be combined, separated, interchanged and / or rearranged without departing from the technical concept of the present disclosure.

[0026] The use of cross-hatching and / or shading in the accompanying drawings is generally used to make the boundaries between adjacent components clear. As such, unless otherwise specified, the presence or absence of cross-hatching or shading does not convey or indicate any preference or requirement for the specific materials, material properties, dimensions, proportions, commonalities between the components shown, and / or any other characteristics, attributes, properties, etc. of the components. In addition, in the accompanying drawings, the sizes and relative sizes of the components may be exaggerated for clarity and / or descriptive purposes. When the exemplary embodiments may be implemented differently, the specific process sequence may be performed in a different order than described. For example, two successively described processes may be performed substantially simultaneously or in an order opposite to the described order. In addition, the same figure numbers represent the same components.

[0027] When a component is referred to as being "on" or "over," "connected to," or "coupled to" another component, the component may be directly on, directly connected to, or directly coupled to the other component, or intervening components may be present. However, when a component is referred to as being "directly on," "directly connected to," or "directly coupled to" another component, there are no intervening components. For this purpose, the term "connected" may refer to a physical connection, an electrical connection, etc., with or without intervening components.

[0028] For descriptive purposes, the present disclosure may use spatially relative terms such as "below," "beneath," "below," "above," "upper," "above," "higher," and "side (e.g., as in "sidewall")," to describe the relationship of one component to another (other) component as shown in the accompanying drawings. The spatially relative terms are intended to encompass different orientations of the device in use, operation, and / or manufacture in addition to the orientation depicted in the accompanying drawings. For example, if the device in the accompanying drawings is turned over, components described as "below" or "beneath" other components or features would then be positioned "above" the other components or features. Thus, the exemplary term "below" can encompass both the "above" and "below" orientations. Furthermore, the device may be otherwise oriented (e.g., rotated 90 degrees or at other orientations), and as such, the spatially relative descriptors used herein should be interpreted accordingly.

[0029] The terms used here are for the purpose of describing specific embodiments, and are not intended to be restrictive. As used here, unless the context clearly indicates otherwise, the singular forms "one (kind, person)" and "said (the)" are also intended to include plural forms. In addition, when the terms "comprise" and / or "include" and their variations are used in this specification, it is explained that there are stated features, integral bodies, steps, operations, parts, assemblies and / or their groups, but it is not excluded that there are or add one or more other features, integral bodies, steps, operations, parts, assemblies and / or their groups. It should also be noted that, as used here, the terms "substantially", "approximately" and other similar terms are used as approximate terms and not as degree terms, so that they are used to explain the inherent deviations of the measured values, calculated values ​​and / or provided values ​​that will be recognized by those of ordinary skill in the art.

[0030] Figure 1 It is a structural schematic diagram of a heparin sodium extraction and inactivation device;

[0031] Figure 2 It is a cross-sectional view of a heparin sodium extraction and inactivation device;

[0032] Figure 3 for Figure 2 Enlarged view of part A;

[0033] Figure 4 This is a disassembled diagram of the tube cover mechanism of a heparin sodium extraction and inactivation device;

[0034] Figure 5 It is a cross-sectional view of the upper cover of a heparin sodium extraction and inactivation device;

[0035] like Figure 1-5 As shown, a heparin sodium extraction and inactivation device disclosed in the present invention may include: an inactivation mechanism, a tube cover mechanism, a cleaning mechanism and other components;

[0036] like Figure 1-5 As shown, the inactivation mechanism includes an inactivation tank 1, an input port 14, a motor 15, a shaft 16, an annular tube 18, and a valve 22;

[0037] The motor 15 is installed at the center of the upper surface of the inactivation tank 1, the input port 14 is opened on the upper surface of the inactivation tank 1 and is located on one side of the motor 15, the shaft 16 is installed on the driving end of the motor 15 extending to the inside of the inactivation tank 1, and the plurality of stirring blades 17 are evenly installed on the side of the shaft 16, and the valve 22 is installed on the output pipe of the inactivation tank 1;

[0038] Then the inactivation tank 1 is operated to heat the raw materials in the inactivation tank 1, and at the same time, the motor 15 is operated to drive the stirring blade 17 to rotate through the shaft 16 to stir the raw materials in the inactivation tank 1, and the raw materials are enzymolyzed by the added enzyme, and then the inactivation tank 1 is used to heat the raw materials to inactivate the raw materials. After the inactivation is completed, the valve 22 is opened to discharge the inactivated raw materials from the output pipe of the inactivation tank 1;

[0039] like Figure 1-5 As shown, the tube cover mechanism includes an input tube 2, a cover slot 3, a clamping slot 4, an upper cover 5, a cavity 6, a limit plate 7, a spring 8, a clamping member 9, a center slot 10, a winding rod 11, a pull rope 12, and a knob 13;

[0040] The input tube 2 is installed at the port of the pull rope 12, the cover groove 3 is opened at the port of the input tube 2, the four card slots 4 are rectangularly opened on the side of the input tube 2, the upper cover 5 is arranged in the cover groove 3 adapted thereto, the four cavities 6 are rectangularly opened inside the upper cover 5 and aligned with the four card slots 4, the four cavities 6 are respectively arranged in the four cavities 6, each of the springs 8 is arranged in the corresponding cavity 6 and is on one side of the limiting plate 7, each of the card members 9 is installed at the center of the other side of the corresponding limiting plate 7 and extends to the aligned card slots 4, the center groove 10 is opened at the center inside the upper cover 5, the winding rod 11 is rotatably installed inside the center groove 10, each of the pull ropes 12 is installed at the center of the side of the corresponding limiting plate 7 and the end extends into the center groove 10 and is fixedly connected to the winding rod 11, and the knob 13 is installed at the end of the winding rod 11 extending to the outside of the upper cover 5;

[0041] The rotating knob 13 drives the winding rod 11 to rotate and wind the four drawstrings 12, so that each drawstring 12 pulls the limit plate 7 to move, and each moving limit plate 7 compresses the spring 8 while driving the clamp 9 to move out of the clamping slot 4 and into the cavity 6, so that the fixation of the upper cover 5 can be released, and it is removed to open the input tube 2, and then the raw materials for making heparin sodium are sent into the inactivation tank 1 through the input tube 2 and the input port 14, and then the enzyme is added, the upper cover 5 is covered and the four clamps 9 are aligned with the clamping slot 4, and the knob 13 is loosened to allow each spring 8 to rebound and drive the limit plate 7 to restore its position, thereby driving the clamp 9 to be inserted into the aligned clamping slot 4, and the upper cover 5 is fixed on the input tube 2 again;

[0042] like Figure 1-5 As shown, the cleaning mechanism includes an annular tube 18, a nozzle 19, a water pump 20, and a connecting tube 21;

[0043] The annular tube 18 is installed at the center of the top surface of the inactivation tank 1, and the plurality of nozzles 19 are evenly installed on the side of the annular tube 18 and tilted toward the inner wall of the inactivation tank 1. The water pump 20 is installed on the upper surface of the inactivation tank 1 and the output end is connected to the annular tube 18 pipeline. The input end of the water pump 20 is installed with a connecting pipe 21;

[0044] When the inner wall of the inactivation tank 1 needs to be cleaned, the end of the connecting pipe 21 is placed in the water tank, and then the water pump 20 runs through the connecting pipe 21 to pump the water in the water tank into the annular pipe 18, and finally each nozzle 19 sprays the water onto the inner wall of the inactivation tank 1. After the water is sprayed onto the inner wall, it is continuously flushed downward, thereby cleaning the inner wall of the inactivation tank 1, until clean water flows out of the output end of the inactivation tank 1, indicating that the cleaning is completed, and the water pump 20 can be turned off.

[0045] In the description of this specification, the description with reference to the terms "one embodiment / method", "some embodiments / methods", "example", "specific example", or "some examples" means that the specific features, structures, materials or characteristics described in conjunction with the embodiment / method or example are included in at least one embodiment / method or example of the present application. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment / method or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments / methods or examples in a suitable manner. In addition, those skilled in the art may combine and combine different embodiments / methods or examples described in this specification and the features of different embodiments / methods or examples, unless they are contradictory.

[0046] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In the description of this application, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0047] Those skilled in the art should understand that the above embodiments are only for the purpose of clearly illustrating the present disclosure, and are not intended to limit the scope of the present disclosure. For those skilled in the art, other changes or modifications may be made based on the above disclosure, and these changes or modifications are still within the scope of the present disclosure.

Claims

1. A heparin sodium extraction and inactivation device, characterized in that: include: An inactivation mechanism, which is used to inactivate the heparin sodium raw material; A tube cover mechanism, which is the input end of the device; The tube cover mechanism comprises an input tube (2), an upper end of the input tube (2) is provided with a cover groove (3), a side surface of the cover groove (3) is provided with four rectangular slots (4) on one side of the cover groove (3), an upper cover (5) matching the cover groove (3) is provided in the cover groove (3), a cavity (6) is provided inside the upper cover (5) on one side of each slot (4), a limit plate (7) is provided in each cavity (6), and a spring (8) is provided in each cavity (6) on one side of the limit plate (7). ), a clamping member (9) extending into the aligned clamping slot (4) is installed at the center of the other side of each of the limiting plates (7), a center slot (10) is opened at the inner center of the upper cover (5), a winding rod (11) is rotatably installed in the center slot (10), a pull rope (12) whose end extends into the center slot (10) and is fixedly connected to the winding rod (11) is installed at the center of the side of each of the limiting plates (7), and the end of the winding rod (11) extends to the outside of the upper cover (5) and is installed with a knob (13); A cleaning mechanism is used for cleaning the inner wall of the device.

2. A heparin sodium extraction and inactivation device according to claim 1, characterized in that: The inactivation mechanism comprises an inactivation tank (1) installed at the lower end of an input pipe (2), and an input port (14) is provided on the upper surface of the inactivation tank (1) just below the input pipe (2).

3. A heparin sodium extraction and inactivation device according to claim 2, characterized in that: A motor (15) is installed at the center of the upper surface of the inactivation tank (1), the driving end of the motor (15) extends into the inactivation tank (1) and is installed with a shaft (16), and a plurality of evenly distributed stirring blades (17) are installed on the surface of the shaft (16).

4. A heparin sodium extraction and inactivation device according to claim 1, characterized in that: The cleaning mechanism comprises an annular tube (18) installed at the center of the top surface of the inactivation tank (1), and a plurality of nozzles (19) evenly distributed and inclined toward the inner wall of the inactivation tank (1) are installed on the side of the annular tube (18).

5. A heparin sodium extraction and inactivation device according to claim 4, characterized in that: A water pump (20) having an output end connected to the annular pipe (18) is installed on the upper surface of the inactivation tank (1) at one side of the motor (15), and a connecting pipe (21) is installed at the input end of the water pump (20).

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