A differential diagnostic kit for distinguishing between vaccine immunization and natural infection of a senecavirus

CN224695899UActive Publication Date: 2026-08-28BEIJING ACADEMY OF AGRICULTURE & FORESTRY SCIENCES
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Patent Information

Application Number
CN202522103924.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-09-29
Publication Date
2026-08-28
Estimated Expiration
2035-09-29

AI Technical Summary

Technical Problem

[0003]传统可区分疫苗免疫与自然感染的塞内卡病毒差异化诊断试剂盒需分别对结构蛋白反应孔和非结构蛋白反应孔手动加样,易出现加样量偏差、加样顺序混乱,导致双指标反应不同步

Benefits of technology

1.该可区分疫苗免疫与自然感染的塞内卡病毒差异化诊断试剂盒,由加样单元构成其一部件,当区分疫苗免疫与自然感染的塞内卡病毒差异化时,通过推进杆对两个注射筒内部吸入同量的所需诊断的试液,将注射筒套设在套环内部,转动转把,其通过第二磁框带动十字杆随之转动,十字杆通过第一磁框带动压板随之转动,当压板置于注射筒顶面时,松开压板,在第二磁框与第一磁框磁性相斥限制下,将压板向注射筒顶面推动,对注射筒压制,此时推动推进杆,将注射筒内部试液向诊断试剂盒内部同步同量推动,诊断试剂盒内部加入同量检测试液,使检测数据更精准;

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Abstract

The utility model discloses a kind of Seneca virus differentiation diagnosis kits of distinguishable vaccine immunization and natural infection, including diagnostic reagent kit, sample adding unit, the sample adding unit is placed on the upper portion of diagnostic reagent kit, the sample adding unit includes syringe and push rod, for pushing push rod to inside detection reagent inside syringe inside diagnostic reagent kit Synchronous quantitative push, protection unit, the protection unit is placed below sample adding unit, the protection unit includes sleeve and sliding pipe, under the sleeve and sliding pipe and the bottom sleeve of syringe limit, can avoid foreign matter into syringe and diagnostic reagent kit inside, influence reagent solution diagnostic precision, under the limit of sample adding unit, it can be added to the same amount of reagent solution inside diagnostic reagent kit simultaneously, make diagnostic reagent kit diagnostic condition same, under the limit of protection unit, it can be protected to the sample adding place of syringe and diagnostic reagent kit, avoid foreign matter adhere on reagent solution, influence detection precision.
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Description

Technical Field

[0001] This invention relates to the field of test solution diagnostic technology, specifically to a differential diagnostic kit for Seneca virus that can distinguish between vaccine-immunized and naturally infected individuals. Background Technology

[0002] The Seneca virus differential diagnostic kit, capable of distinguishing between vaccine-immunized and naturally infected animals, is a standardized diagnostic tool that uses Seneca virus as the diagnostic target. It employs a dual-indicator detection system targeting both structural and non-structural proteins of the virus to accurately determine the source of Seneca virus antibodies / antigens in animals. The kit includes core testing reagents, supporting consumables, and operating instructions. It is primarily used for disease monitoring, immunization efficacy evaluation, and epidemic tracing in cloven-hoofed animals such as pigs, providing a scientific basis for precise prevention, eradication, and trade quarantine of Seneca virus.

[0003] Traditional differential diagnostic kits for Seneca virus that can distinguish between vaccine-immunized and naturally infected individuals require manual loading of samples into the structural protein reaction wells and the non-structural protein reaction wells, which can easily lead to deviations in sample loading volume and disordered loading order, resulting in asynchronous responses of the two indicators.

[0004] Therefore, a differential diagnostic kit for Seneca virus that can distinguish between vaccine-immunized and naturally infected individuals is needed to address the aforementioned issues. Utility Model Content

[0005] The purpose of this invention is to provide a differential diagnostic kit for Seneca virus that can distinguish between vaccine-immunized and naturally infected individuals, in order to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a differential diagnostic kit for Seneca virus that can distinguish between vaccine-immunized and naturally infected individuals, comprising a diagnostic kit, A sample dispensing unit is positioned above the diagnostic kit. The sample dispensing unit includes an syringe and a push rod, which is used to push the push rod to synchronously and quantitatively dispense the test solution inside the syringe into the diagnostic kit. The protective unit, located below the sample dispensing unit, includes a sleeve and a sliding tube. With the sleeve and sliding tube fitted over the bottom of the syringe, foreign objects are prevented from entering the syringe and diagnostic kit, thus avoiding impact on the accuracy of the test solution. Under the constraint of the sample dispensing unit, the same amount of test solution can be added to the diagnostic kit simultaneously, ensuring identical diagnostic conditions. The protective unit also protects the sample dispensing area of ​​the syringe and diagnostic kit, preventing foreign objects from adhering to the test solution and affecting detection accuracy.

[0007] Preferably, the sample dispensing unit includes a support, an end of which is connected to a collar, an injection cylinder is slidably disposed inside the collar, and a push rod is slidably disposed inside the injection cylinder.

[0008] Preferably, a crossbar is rotatably connected to the top surface of the bracket, a first magnetic frame is slidably disposed on the outer wall of the crossbar, a pressure plate is connected to the bottom of the first magnetic frame, a second magnetic frame is connected to the end of the crossbar away from the bracket, and a throttle is connected to the top surface of the second magnetic frame.

[0009] Preferably, the second magnetic frame and the first magnetic frame are magnetically repulsive, and the inside of the pressure plate is slidably disposed with respect to the outer wall of the cross rod. Under the magnetic repulsion, the pressure plate is pushed to press the syringe and prevent the syringe from sliding out of the collar.

[0010] Preferably, there are two syringes symmetrically distributed around the center line of the support. The outer wall of each syringe is marked with graduations. With the two syringes in place, the same amount of reagent can be added to the inside of the diagnostic kit simultaneously via the push rod.

[0011] Preferably, the protective unit includes a sleeve, a first magnetic ring is connected to the inner wall of the sleeve, a second magnetic ring is slidably disposed inside the sleeve, a sliding tube is connected to the side wall of the second magnetic ring, and a rubber ring is connected to the end of the sliding tube away from the second magnetic ring.

[0012] Preferably, the first magnetic ring and the second magnetic ring are magnetically repulsive, and the outer wall of the sliding tube and the inside of the sleeve are slidably arranged. Under the restriction of magnetic repulsion, the sliding tube and the rubber ring can be pushed so that the rubber ring is tightly attached to the bottom of the syringe and adsorbed, avoiding gaps and adhesion to the test liquid.

[0013] Preferably, the rubber ring is made of rubber and is fitted inside the outer wall of the syringe barrel, so that it adheres tightly to the outer wall of the syringe barrel under the constraint of the rubber ring.

[0014] Compared with the prior art, the beneficial effects of this utility model are: 1. This differential diagnostic kit for Seneca virus that can distinguish between vaccine-immunized and naturally infected individuals consists of a sample dispensing unit. When differentiating between vaccine-immunized and naturally infected Seneca virus, the same amount of the required diagnostic solution is drawn into two syringes via the push rod. The syringes are then placed inside the collar. Rotating the handle causes the crossbar to rotate via the second magnetic frame. The crossbar, in turn, causes the pressure plate to rotate via the first magnetic frame. When the pressure plate is positioned on the top surface of the syringe, it is released. Under the magnetic repulsion between the second and first magnetic frames, the pressure plate is pushed towards the top surface of the syringe, pressing it down. At this point, pushing the push rod simultaneously and in the same amount pushes the solution from the syringe into the diagnostic kit, resulting in more accurate test data. 2. This differential diagnostic kit for Seneca virus, which can distinguish between vaccine-immunized and naturally infected individuals, consists of a protective unit as one component. When the syringe is installed above the diagnostic kit, the bottom end of the syringe is fitted inside the rubber ring. The syringe pushes the rubber ring and the sliding tube, causing the sliding tube to drive the second magnetic ring to slide into the sleeve. Under the magnetic repulsion constraint of the first and second magnetic rings, the second magnetic ring, the sliding tube, and the rubber ring are pushed upward, so that the rubber ring is in close contact with the outer wall of the syringe. Under the constraint of the sliding tube and the sleeve, the connection between the syringe and the diagnostic kit can be protected, preventing impurities from adhering to the test solution and affecting the detection accuracy. Attached Figure Description

[0015] Figure 1 This is a three-dimensional view of the structure of this utility model.

[0016] Figure 2 This is a schematic diagram of the sample feeding unit and the protection unit of this utility model.

[0017] Figure 3 This is a structural sample unit diagram of the present utility model.

[0018] Figure 4 This is a cross-sectional schematic diagram of the sample feeding unit of this utility model.

[0019] Figure 5 This is a structural protection unit diagram of the present invention.

[0020] Figure 6 This is a cross-sectional schematic diagram of the structural protection unit of this utility model.

[0021] In the diagram: 1. Diagnostic reagent kit; 2. Sample dispensing unit; 3. Protective unit; 21. Support; 22. Collar; 23. Syringe; 24. Push rod; 25. Cross rod; 26. First magnetic frame; 27. Pressure plate; 28. Second magnetic frame; 29. ​​Rotary handle; 31. Sleeve; 32. First magnetic ring; 33. Second magnetic ring; 34. Slide tube; 35. Rubber ring. Detailed Implementation

[0022] To provide a clearer understanding of the technical features, objectives, and effects of this utility model, the specific embodiments of this utility model are now described with reference to the accompanying drawings.

[0023] Example 1 Reference Figure 1 and Figure 2 This is the first embodiment of the present invention, which provides a differential diagnostic kit for Seneca virus that can distinguish between vaccine-immunized and naturally infected individuals, including a diagnostic kit 1. The sample dispensing unit 2 is positioned above the diagnostic kit 1. The sample dispensing unit 2 includes an injection cylinder 23 and a push rod 24, which is used to push the push rod 24 to synchronously and quantitatively push the test solution inside the injection cylinder 23 into the diagnostic kit 1. The protective unit 3 is located below the sample application unit 2. The protective unit 3 includes a sleeve 31 and a sliding tube 34. With the sleeve 31 and the sliding tube 34 covering the bottom of the syringe 23, it can prevent foreign objects from entering the syringe 23 and the interior of the diagnostic reagent kit 1, thus affecting the accuracy of the test solution diagnosis.

[0024] During use, under the restriction of the sample addition unit 2, the same amount of test solution can be added to the inside of the diagnostic kit 1 simultaneously, so that the diagnostic conditions of the diagnostic kit 1 are the same. Under the restriction of the protection unit 3, the syringe 23 and the sample addition point of the diagnostic kit 1 can be protected to prevent foreign objects from adhering to the test solution and affecting the detection accuracy.

[0025] Example 2 Reference Figure 3 and Figure 4 This is the second embodiment of the present invention. Unlike the previous embodiment, this embodiment is further optimized based on the above embodiment, as follows: The sample dispensing unit 2 includes a support 21, with a collar 22 connected to the end of the support 21. An injection cylinder 23 is slidably disposed inside the collar 22, and a push rod 24 is slidably disposed inside the injection cylinder 23. A cross rod 25 is rotatably connected to the top surface of the support 21. A first magnetic frame 26 is slidably disposed on the outer wall of the cross rod 25. A pressure plate 27 is connected to the bottom of the first magnetic frame 26. A second magnetic frame 28 is connected to the end of the cross rod 25 away from the support 21. A handle 29 is connected to the top surface of the second magnetic frame 28.

[0026] The second magnetic frame 28 and the first magnetic frame 26 are magnetically repulsive. The inside of the pressure plate 27 is slidably disposed with the outer wall of the cross rod 25. Under the magnetic repulsion, the pressure plate 27 is pushed to press the syringe 23, preventing the syringe 23 from sliding out of the collar 22.

[0027] There are two syringes 23, which are symmetrically distributed around the center line of the support 21. The outer wall of the syringe 23 is marked with graduations. Under the constraint of the two syringes 23, the test solution can be added to the inside of the diagnostic reagent kit 1 synchronously and in the same amount through the push rod 24.

[0028] In use, when differentiating between vaccine-immunized and naturally infected Seneca virus, the same amount of the required diagnostic solution is drawn into the two syringes 23 by the push rod 24. The syringes 23 are then placed inside the collar 22. The handle 29 is rotated, which drives the crossbar 25 to rotate via the second magnetic frame 28. The crossbar 25 drives the pressure plate 27 to rotate via the first magnetic frame 26. When the pressure plate 27 is placed on the top surface of the syringes 23, it is released. Under the magnetic repulsion between the second magnetic frame 28 and the first magnetic frame 26, the pressure plate 27 is pushed towards the top surface of the syringes 23, pressing them down. At this time, the push rod 24 is pushed to simultaneously and in the same amount into the diagnostic kit 1. The same amount of test solution is added to the diagnostic kit 1, making the test data more accurate.

[0029] Example 3 Reference Figure 5 and Figure 6 This is the third embodiment of the present invention. Unlike the previous embodiment, this embodiment is further optimized based on the above embodiments, as detailed below: The protective unit 3 includes a sleeve 31, a first magnetic ring 32 connected to the inner wall of the sleeve 31, a second magnetic ring 33 slidably disposed inside the sleeve 31, a sliding tube 34 connected to the side wall of the second magnetic ring 33, and a rubber ring 35 connected to the end of the sliding tube 34 away from the second magnetic ring 33.

[0030] The first magnetic ring 32 and the second magnetic ring 33 are magnetically repulsive. The outer wall of the sliding tube 34 and the inside of the sleeve 31 are slidably arranged. Under the restriction of magnetic repulsion, the sliding tube 34 and the rubber ring 35 can be pushed so that the rubber ring 35 is tightly attached to the bottom of the syringe 23 and adsorbed, avoiding gaps and adhesion to the test liquid.

[0031] The rubber ring 35 is made of rubber and is fitted inside the outer wall of the injection cylinder 23. Under the constraint of the rubber ring 35, it adheres tightly to the outer wall of the injection cylinder 23.

[0032] When in use, when the syringe 23 is installed above the diagnostic reagent kit 1, the bottom end of the syringe 23 is fitted inside the rubber ring 35. The syringe 23 pushes the rubber ring 35 and the slide tube 34, causing the slide tube 34 to drive the second magnetic ring 33 to slide into the sleeve 31. Under the magnetic repulsion constraint of the first magnetic ring 32 and the second magnetic ring 33, the second magnetic ring 33, the slide tube 34 and the rubber ring 35 are pushed upward, so that the rubber ring 35 is in close contact with the outer wall of the syringe 23. Under the constraint of the slide tube 34 and the sleeve 31, the connection between the syringe 23 and the diagnostic reagent kit 1 can be protected to prevent impurities from adhering to the test solution and affecting the detection accuracy.

[0033] The above description is merely an illustrative embodiment of this utility model and is not intended to limit the scope of this utility model. Any equivalent changes and modifications made by those skilled in the art without departing from the concept and principles of this utility model should fall within the protection scope of this utility model. Furthermore, it should be noted that the components of this utility model are not limited to the overall application described above. Each technical feature described in the specification of this utility model can be used individually or in combination as needed. Therefore, this utility model naturally covers other combinations and specific applications related to the points of this utility model.

Claims

1. A differential diagnostic kit for Seneca virus that can distinguish between vaccine-immunized and naturally infected individuals, characterized in that, Including diagnostic kits (1). The sample dispensing unit (2) is placed above the diagnostic kit (1). The sample dispensing unit (2) includes a syringe (23) and a push rod (24) for pushing the push rod (24) to synchronously and quantitatively push the test solution inside the syringe (23) into the diagnostic kit (1). The protective unit (3) is placed below the sample dispensing unit (2). The protective unit (3) includes a sleeve (31) and a slide tube (34). With the sleeve (31) and slide tube (34) and the bottom of the syringe (23) being fitted with a restrictive sleeve, it can prevent foreign objects from entering the syringe (23) and the diagnostic reagent kit (1) and affecting the accuracy of the test solution diagnosis.

2. The differential diagnostic kit for Seneca virus that can distinguish between vaccine immunization and natural infection according to claim 1, characterized in that: The sample dispensing unit (2) includes a support (21), and a collar (22) is connected to the end of the support (21). An injection cylinder (23) is slidably disposed inside the collar (22), and a push rod (24) is slidably disposed inside the injection cylinder (23).

3. The differential diagnostic kit for Seneca virus that can distinguish between vaccine immunization and natural infection according to claim 2, characterized in that: The top surface of the bracket (21) is rotatably connected to a cross rod (25), and a first magnetic frame (26) is slidably provided on the outer wall of the cross rod (25). A pressure plate (27) is connected to the bottom of the first magnetic frame (26), and a second magnetic frame (28) is connected to the end of the cross rod (25) away from the bracket (21). A throttle (29) is connected to the top surface of the second magnetic frame (28).

4. The differential diagnostic kit for Seneca virus that can distinguish between vaccine immunization and natural infection according to claim 3, characterized in that: The second magnetic frame (28) and the first magnetic frame (26) are magnetically repelled, and the inside of the pressure plate (27) is slidably disposed with respect to the outer wall of the cross rod (25).

5. The differential diagnostic kit for Seneca virus that can distinguish between vaccine immunization and natural infection according to claim 2, characterized in that: There are two syringes (23), which are symmetrically distributed around the center line of the support (21). The outer wall of the syringe (23) is marked with graduations.

6. The differential diagnostic kit for Seneca virus that can distinguish between vaccine immunization and natural infection according to claim 1, characterized in that: The protective unit (3) includes a sleeve (31), the inner wall of the sleeve (31) is connected to a first magnetic ring (32), a second magnetic ring (33) is slidably disposed inside the sleeve (31), a sliding tube (34) is connected to the side wall of the second magnetic ring (33), and a rubber ring (35) is connected to the end of the sliding tube (34) away from the second magnetic ring (33).

7. The differential diagnostic kit for Seneca virus that can distinguish between vaccine immunization and natural infection according to claim 6, characterized in that: The first magnetic ring (32) and the second magnetic ring (33) are magnetically repulsive, and the outer wall of the sliding tube (34) is slidably disposed inside the sleeve (31).

8. The differential diagnostic kit for Seneca virus that can distinguish between vaccine immunization and natural infection according to claim 6, characterized in that: The rubber ring (35) is made of rubber and is fitted inside the injection cylinder (23) on the outer wall.