Dialysis device
Patent Information
- Application Number
- CN202522174187.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-10-14
- Publication Date
- 2026-09-04
- Estimated Expiration
- 2035-10-14
AI Technical Summary
[0005]本实用新型的主要目的在于提供一种透析装置,以解决现有技术中透析装置中的透析袋放置稳定性较差的问题
[0016] The present invention provides a dialysis apparatus housing with a receiving cavity for containing dialysate. A fixing structure is suspended within the receiving cavity and includes a first through hole, a second through hole, and a fixing cavity. Both the first and second through holes communicate with the fixing cavity, allowing the fixing cavity to communicate with the receiving cavity through the first and second through holes. A stirring structure is movably disposed within the receiving cavity to stir the dialysate. A separating assembly is disposed within the fixing cavity and includes multiple separating structures spaced apart around a first preset axis to divide the fixing cavity into multiple sub-fixed cavities for containing dialysate and dialysis bags. This allows the operator to place the human fibrinogen sample requiring dialysis into a dialysis bag and then place the dialysis bag into the fixing cavity of the fixing structure. This prevents the dialysis bag from floating or sticking to the cavity wall, ensuring the stability of the dialysis bag and thus guaranteeing the reliability of dialysis of the human fibrinogen sample. This solves the problem of poor dialysis bag stability in existing dialysis apparatuses. Meanwhile, the fixing chamber of the fixed structure is connected to the receiving chamber through the first and second through holes, ensuring that the dialysate in the receiving chamber enters the fixing chamber through the first and second through holes. This further ensures contact between the dialysis bag and the dialysate, guaranteeing the reliability of dialysis for human fibrinogen samples. Simultaneously, the dialysis device can move within the receiving chamber via a stirring structure, achieving agitation of the dialysate. This replaces manual stirring by operators, reducing their workload and ensuring automated stirring of the dialysis device. This allows the dialysate to be stably and continuously agitated, ensuring the continuity and uniformity of dialysate flow. Furthermore, the arrangement of multiple partitions dividing the fixed chamber into multiple sub-fixed chambers increases the number of dialysis bags that the fixed structure can accommodate. This allows the fixed structure to simultaneously fix multiple dialysis bags, enabling simultaneous dialysis and ensuring the stability of multiple dialysis bags, thus improving the dialysis efficiency and reliability of the dialysis device.
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Figure CN224711862U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of biological experimental device technology, and more specifically, to a dialysis device. Background Technology
[0002] Currently, fibrinogen is a protein synthesized by the liver with clotting function and is an important component of blood plasma, playing a crucial role in physiological and pathological processes such as cell adhesion, inflammatory responses, and tissue repair. In the biopharmaceutical field, particularly in the production and quality control of plasma products, accurate analysis of the purity, activity, and structural integrity of human fibrinogen is essential. Peptide mapping analysis is a key technique for identifying protein characteristics, detecting degradation products, and monitoring the stability of production processes.
[0003] In existing technologies, before peptide mapping analysis, operators typically need to dialyze enzymatically digested human fibrinogen samples. Operators usually immerse the dialysis bag containing the sample directly in a beaker or other open container filled with dialysis fluid. This process replaces the buffer system and removes small molecule impurities or salts, ensuring the accuracy and reliability of subsequent mass spectrometry or chromatographic analysis.
[0004] However, dialysis bags are prone to floating or drifting in the dialysis solution and tend to adhere to the inner wall of the container. When part of the dialysis bag floats above the liquid surface or adheres tightly to the container wall, part of its membrane surface cannot fully contact the dialysis solution, resulting in a significant reduction in the effective area available for substance exchange, which reduces the dialysis reliability and completeness of the dialysis device. Utility Model Content
[0005] The main objective of this invention is to provide a dialysis device to solve the problem of poor stability of dialysis bags in existing dialysis devices.
[0006] To achieve the above objectives, this utility model provides a dialysis device, comprising: a housing having a receiving cavity for containing dialysate; a fixing structure suspended within the receiving cavity, the fixing structure having a first through hole, a second through hole, and a fixing cavity, the first through hole and the second through hole both communicating with the fixing cavity, so that the fixing cavity communicates with the receiving cavity through the first through hole and the second through hole; a stirring structure movably disposed within the receiving cavity for stirring the dialysate; and a separating assembly disposed within the fixing cavity, the separating assembly including multiple separating structures spaced apart around a first preset axis to divide the fixing cavity into multiple sub-fixed cavities for containing dialysate and dialysis bags.
[0007] Furthermore, the dialysis apparatus also includes: a cooling structure, the cooling end of which is disposed facing the cavity wall of the receiving cavity to cool the dialysate; wherein the housing also has a receiving cavity, the cooling structure is disposed inside the receiving cavity, and the receiving cavity is located outside the receiving cavity; and / or, the cooling end of the cooling structure is attached to the cavity wall of the receiving cavity to cool the dialysate; and / or, the cooling structure is a semiconductor cooling structure.
[0008] Furthermore, the cooling structure includes a heat dissipation structure disposed on the heat dissipation end of the cooling structure away from the receiving cavity, in order to dissipate heat from the heat dissipation end.
[0009] Furthermore, each partition structure has a first mating part, and the fixing structure has multiple second mating parts, which are arranged one-to-one with the multiple first mating parts; wherein, one of the first mating parts and the second mating parts is a protrusion, and the other of the first mating parts and the second mating parts is a recess, and the protrusion extends into the recess to engage with the recess.
[0010] Furthermore, the dialysis device also includes a hanging structure, one end of which is connected to a fixed structure, and the other end of which is connected to a housing, so that the fixed structure is suspended inside the receiving cavity.
[0011] Furthermore, there are multiple hanging structures, which are spaced apart around a first preset axis; and / or, the hanging structure is a hook.
[0012] Furthermore, the partition structure is plate-shaped and has a third through hole that communicates with the sub-fixed cavity; there are multiple third through holes, which are divided into multiple groups, and each group of third through holes includes multiple third through holes. The multiple groups of third through holes are spaced apart along the length direction of the partition structure, and the multiple third through holes in each group are spaced apart along the width direction of the partition structure.
[0013] Furthermore, the dialysis apparatus also includes: a temperature control system, comprising a temperature detection structure and a control structure, wherein the temperature detection structure is mounted on the housing and the detection part of the temperature detection structure extends into the receiving cavity to detect the temperature of the dialysate; both the temperature detection structure and the cooling structure are connected to the control structure, and the control structure is configured to control the opening and closing of the cooling structure based on the detection data of the temperature detection structure.
[0014] Furthermore, the stirring structure includes a connecting part and multiple stirring parts that are interconnected. The multiple stirring parts are spaced apart around a second preset axis, and at least some of the stirring parts are arranged in an arc shape. The dialysis device also includes a driving structure that is driven to the connecting part to drive the connecting part to rotate the stirring parts around the second preset axis.
[0015] Furthermore, the dialysis device also includes a timer connected to the drive structure, and a control structure configured to control the start and stop of the drive structure according to a preset time of the timer; and / or, an optocoupler isolation structure connected to both the cooling structure and the control structure, and the control structure controlling the opening and closing of the cooling structure through the optocoupler isolation structure.
[0016] The present invention provides a dialysis apparatus housing with a receiving cavity for containing dialysate. A fixing structure is suspended within the receiving cavity and includes a first through hole, a second through hole, and a fixing cavity. Both the first and second through holes communicate with the fixing cavity, allowing the fixing cavity to communicate with the receiving cavity through the first and second through holes. A stirring structure is movably disposed within the receiving cavity to stir the dialysate. A separating assembly is disposed within the fixing cavity and includes multiple separating structures spaced apart around a first preset axis to divide the fixing cavity into multiple sub-fixed cavities for containing dialysate and dialysis bags. This allows the operator to place the human fibrinogen sample requiring dialysis into a dialysis bag and then place the dialysis bag into the fixing cavity of the fixing structure. This prevents the dialysis bag from floating or sticking to the cavity wall, ensuring the stability of the dialysis bag and thus guaranteeing the reliability of dialysis of the human fibrinogen sample. This solves the problem of poor dialysis bag stability in existing dialysis apparatuses. Meanwhile, the fixing chamber of the fixed structure is connected to the receiving chamber through the first and second through holes, ensuring that the dialysate in the receiving chamber enters the fixing chamber through the first and second through holes. This further ensures contact between the dialysis bag and the dialysate, guaranteeing the reliability of dialysis for human fibrinogen samples. Simultaneously, the dialysis device can move within the receiving chamber via a stirring structure, achieving agitation of the dialysate. This replaces manual stirring by operators, reducing their workload and ensuring automated stirring of the dialysis device. This allows the dialysate to be stably and continuously agitated, ensuring the continuity and uniformity of dialysate flow. Furthermore, the arrangement of multiple partitions dividing the fixed chamber into multiple sub-fixed chambers increases the number of dialysis bags that the fixed structure can accommodate. This allows the fixed structure to simultaneously fix multiple dialysis bags, enabling simultaneous dialysis and ensuring the stability of multiple dialysis bags, thus improving the dialysis efficiency and reliability of the dialysis device. Attached Figure Description
[0017] The accompanying drawings, which form part of this application, are used to provide a further understanding of the present invention. The illustrative embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an undue limitation of the present invention. In the drawings:
[0018] Figure 1 A partial structural schematic diagram of one embodiment of the dialysis apparatus according to the present invention is shown;
[0019] Figure 2 A partial structural schematic diagram of another embodiment of the dialysis apparatus according to the present invention is shown;
[0020] Figure 3 It shows Figure 1 A partial structural diagram of a dialysis device;
[0021] Figure 4 It shows Figure 1 A partial structural diagram of a dialysis device;
[0022] Figure 5 It shows Figure 1 A schematic diagram of the cooling structure of the dialysis device.
[0023] The above figures include the following reference numerals:
[0024] 10. Box body; 11. Receiving cavity;
[0025] 20. Fixed structure; 21. Sub-fixed cavity; 22. Second mating part;
[0026] 30. Stirring structure; 31. Stirring section;
[0027] 40. Divided structure;
[0028] 50. Refrigeration structure; 51. Refrigeration end; 52. Heat dissipation end;
[0029] 60. Hanging structure;
[0030] 70. Temperature control system;
[0031] 80. Drive structure;
[0032] 90. Timer. Detailed Implementation
[0033] It should be noted that, unless otherwise specified, the embodiments and features described in this application can be combined with each other. The present invention will now be described in detail with reference to the accompanying drawings and embodiments.
[0034] It should be noted that, unless otherwise specified, all technical and scientific terms used in this application have the same meaning as commonly understood by one of ordinary skill in the art to which this application pertains.
[0035] In this utility model, unless otherwise stated, directional terms such as "upper" and "lower" are generally used in relation to the direction shown in the accompanying drawings, or in relation to the vertical, perpendicular, or gravitational direction; similarly, for ease of understanding and description, "left" and "right" are generally used in relation to the left and right shown in the accompanying drawings; "inner" and "outer" refer to the inner and outer contours of each component itself, but the above directional terms are not used to limit this utility model.
[0036] To address the problem of poor stability in the placement of dialysis bags in existing dialysis devices, this application provides a dialysis device.
[0037] like Figures 1 to 5 As shown, the dialysis apparatus includes a housing 10, a fixing structure 20, a stirring structure 30, and a partitioning assembly. The housing 10 has a receiving cavity 11 for containing dialysate. The fixing structure 20 is suspended within the receiving cavity 11 and has a first through hole, a second through hole, and a fixing cavity. Both the first and second through holes communicate with the fixing cavity, allowing the fixing cavity to communicate with the receiving cavity 11 through the first and second through holes. The stirring structure 30 is movably disposed within the receiving cavity 11 to stir the dialysate. The partitioning assembly is disposed within the fixing cavity and includes multiple partitioning structures 40. The multiple partitioning structures 40 are spaced apart around a first preset axis to divide the fixing cavity into multiple sub-fixed cavities 21 for containing dialysate and dialysis bags.
[0038] Using the technical solution of this embodiment, the dialysis apparatus housing 10 has a receiving cavity 11 for containing dialysate. A fixing structure 20 is suspended inside the receiving cavity 11. The fixing structure 20 has a first through hole, a second through hole, and a fixing cavity. Both the first through hole and the second through hole communicate with the fixing cavity, so that the fixing cavity communicates with the receiving cavity 11 through the first through hole and the second through hole. A stirring structure 30 is movably disposed inside the receiving cavity 11 to stir the dialysate. A separating assembly is disposed inside the fixing cavity. The separating assembly includes multiple separating structures 40, which are spaced apart around a first preset axis to divide the fixing cavity into multiple sub-fixed cavities 21 for containing dialysate and dialysis bags. In this way, the operator places the fibrinogen sample requiring dialysis into a dialysis bag, and then places the dialysis bag into the fixed cavity of the fixing structure 20. This prevents the dialysis bag from floating or sticking to the cavity wall of the receiving cavity 11, ensuring the stability of the dialysis bag and thus guaranteeing the reliability of dialysis of the human fibrinogen sample. This solves the problem of poor placement stability of dialysis bags in existing dialysis devices. Simultaneously, the fixed cavity of the fixing structure 20 is connected to the receiving cavity 11 through the first and second through holes, ensuring that the dialysis fluid in the receiving cavity 11 enters the fixed cavity through the first and second through holes. This further ensures contact between the dialysis bag and the dialysis fluid, guaranteeing the reliability of dialysis of the human fibrinogen sample. Meanwhile, the dialysis unit can move within the receiving cavity 11 via the stirring structure 30, achieving agitation of the dialysate. This replaces the manual stirring process, reducing the labor intensity of the staff and ensuring automated stirring of the dialysis unit. This allows the dialysate to be subjected to stable and continuous stirring, ensuring the continuity and uniformity of the dialysate flow. Furthermore, the arrangement of multiple partition structures 40 dividing the fixed cavity into multiple sub-fixed cavities 21 increases the number of dialysis bags that the fixed structure 20 can accommodate. This allows the fixed structure 20 to simultaneously fix multiple dialysis bags, enabling simultaneous dialysis with multiple bags. It also ensures the stability of the placement of multiple dialysis bags, improving the dialysis efficiency and reliability of the dialysis unit.
[0039] In this embodiment, the dialysate contains a 1% ammonium bicarbonate solution.
[0040] In this embodiment, the fixing structure 20 is cylindrical, and the first preset axis is consistent with the central axis of the cylinder.
[0041] Specifically, the fixed structure 20 includes a cylindrical body and a circular cover movably disposed on the cylindrical body. The circular cover has a first through hole, the cylindrical body has a receiving cavity, the bottom wall of the receiving cavity has a second through hole, and there are multiple second through holes. The multiple second through holes are divided into multiple groups, and each group of second through holes includes multiple second through holes. The multiple groups of second through holes are spaced apart around a first preset axis, and the multiple second through holes in each group are spaced apart in a direction perpendicular to the first preset axis.
[0042] Specifically, the direction perpendicular to the first preset axis is consistent with the straight line direction located on the bottom wall of the receiving cavity and passing through the first preset axis.
[0043] Optionally, there may be one first through hole.
[0044] Optionally, there are multiple first through holes, and multiple first through holes are provided in a one-to-one correspondence with multiple second through holes.
[0045] like Figure 1 As shown, the dialysis apparatus also includes a cooling structure 50. The cooling end 51 of the cooling structure 50 is positioned towards the cavity wall of the receiving cavity 11 to cool the dialysate. The housing 10 also has a receiving cavity, within which the cooling structure 50 is disposed, with the receiving cavity located outside the receiving cavity 11; and / or, the cooling end 51 of the cooling structure 50 is attached to the receiving cavity 11 to cool the dialysate; and / or, the cooling structure 50 is a semiconductor cooling structure 50. Thus, the cooling end 51 of the cooling structure 50, positioned within the receiving cavity, can continuously cool the dialysate within the receiving cavity 11, maintaining the dialysate at a consistently low temperature. This provides a stable and reliable low-temperature experimental environment for the human fibrinogen sample, ensuring the dialysis effect of the dialysis apparatus and preventing denaturation or degradation of the human fibrinogen sample during the prolonged dialysis process, fundamentally ensuring the accuracy and reliability of subsequent peptide mapping analysis.
[0046] In this embodiment, the housing 10 has a sandwich layer that forms a receiving cavity. The receiving cavity and the receiving cavity 11 share the same cavity wall, and the cooling end 51 of the cooling structure 50 is attached to the cavity wall.
[0047] In this embodiment, as Figure 1 As shown, the box 10 is arranged in the shape of a cuboid.
[0048] In another embodiment, such as Figure 2 As shown, the box 10 is cylindrical.
[0049] Specifically, the chamber 10 also includes a cover, which is used to cover the receiving cavity 11 to isolate it from the external environment and ensure the independence and stability of the dialysis environment. Figure 5As shown, the cooling structure 50 is a semiconductor cooling chip, which includes a heat-absorbing plate, a heat-dissipating plate, a metal guide plate, an N-type semiconductor, and a P-type semiconductor. Multiple N-type and P-type semiconductors are arranged in the order NNPPN… to form the cooling section. Adjacent N-type and P-type semiconductors are connected by the metal guide plate. The heat-absorbing plate and the heat-insulating plate are respectively located at opposite ends of the cooling section. This arrangement allows heat to be transferred from the receiving cavity 11 to the outside, ensuring that the dialysate in the receiving cavity 11 maintains a constant temperature of 4°C, as required for dialysis of human fibrinogen samples, thus guaranteeing the reliability and stability of the dialysis device.
[0050] In this embodiment, the cooling structure 50 includes a heat dissipation structure. The heat dissipation structure is disposed on the heat dissipation end 52 of the cooling structure 50, away from the receiving cavity 11, to dissipate heat from the heat dissipation end 52. Thus, the heat dissipation structure disposed on the heat dissipation end 52 of the cooling structure 50 can dissipate heat from the heat dissipation end 52 of the cooling structure 50, efficiently and quickly dissipating the heat generated by the cooling structure 50 during operation to the external environment. This allows the cooling structure 50 to continuously and stably cool or lower the dialysate in the receiving cavity 11, ensuring the continuous high efficiency and long-term operational stability of the cooling structure 50.
[0051] In this embodiment, the heat dissipation structure is a fan.
[0052] like Figure 3 and Figure 4 As shown, each partition structure 40 has a first mating part, and the fixing structure 20 has multiple second mating parts 22, which are arranged one-to-one with the multiple first mating parts. One of the first and second mating parts 22 is a protrusion, and the other is a recess. The protrusion extends into the recess to engage with it. This engagement of the first and second mating parts 22 enables rapid and stable assembly between the partition structure 40 and the fixing structure 20, ensuring reliable connection while also facilitating the assembly and disassembly of the multiple partition structures 40, thus achieving flexibility in the assembly and disassembly of the partition components. Furthermore, this arrangement allows the multiple partition structures 40 to be assembled according to the requirements of dialysis experiments, adapting to dialysis bags of different specifications and sizes, improving the versatility of the dialysis device, and increasing its utilization rate and experimental efficiency. Additionally, the arrangement of the first and second mating parts 22 makes the processing methods more flexible and diverse, improving the processing flexibility of the staff.
[0053] In this embodiment, the first mating part is a protrusion, and the second mating part 22 is a recess.
[0054] In an embodiment not shown in the accompanying drawings, the first mating part is a recess and the second mating part is a protrusion.
[0055] Specifically, the partition structure 40 is plate-shaped. This allows the partition structure 40 to form a first mating part, enabling workers to directly engage the partition structure 40 with the second mating part 22, improving assembly and disassembly efficiency. Simultaneously, the plate-shaped design simplifies the formation of the partition structure 40, facilitating processing and increasing worker efficiency.
[0056] Optionally, the cover of the partition structure 40 also has a second mating part 22, so that both ends of the partition structure 40 can be inserted into the second mating part 22, thereby improving the installation stability of the partition structure 40. Figure 2 and Figure 3 As shown, the dialysis device also includes a hanging structure 60. One end of the hanging structure 60 is connected to the fixing structure 20, and the other end is connected to the housing 10, so that the fixing structure 20 is suspended inside the receiving cavity 11. In this way, the fixing structure 20 is suspended inside the receiving cavity 11 through the hanging structure 60, ensuring the reliability of the fixing structure 20's suspension, thereby ensuring that the dialysis bag can be stably placed in the dialysis fluid, thus achieving the dialysis reliability of the dialysis device. At the same time, the way the hanging structure 60 is set up allows operators to easily and conveniently hang the fixing structure 20 on the housing 10, improving the operator's ease of operation and efficiency.
[0057] In this embodiment, there are multiple hanging structures 60, which are spaced apart around a first preset axis; and / or, the hanging structures 60 are hooks. In this way, the multiple hanging structures 60 can provide balanced and stable multi-point suspension support for the fixed structure 20, avoiding the phenomenon of the fixed structure 20 shifting due to the flow of the dialysis fluid during the stirring process of the stirring structure 30, thus improving the suspension stability of the fixed structure 20 and providing a stable placement environment for the dialysis bag, thereby improving the placement stability of the dialysis bag.
[0058] In this embodiment, the hanging structure 60 includes a straight section and a hanging section that are connected to each other. The straight section is connected to the fixing structure 20, and the hanging section is arranged in an arc shape and is hung on the box 10.
[0059] In this embodiment, the partition structure 40 is plate-shaped and has a third through hole that communicates with the sub-fixed cavity 21. There are multiple third through holes, divided into multiple groups, each group including multiple third through holes. These groups are spaced apart along the length of the partition structure 40, and the multiple third through holes in each group are spaced apart along the width of the partition structure 40. This allows the multiple third through holes on the partition structure to communicate with the sub-fixed cavity 21, enabling the dialysate to circulate through the first through hole, the second through hole, the sub-fixed cavity 21, and the third through hole, forming a circulation path. This increases the dialysis area between the dialysate and the dialysis bag, further ensuring the completeness and reliability of the dialysis device.
[0060] like Figure 1 As shown, the dialysis apparatus also includes a temperature control system 70. The temperature control system 70 includes a temperature detection structure and a control structure. The temperature detection structure is mounted on the housing 10, and its detection part extends into the receiving cavity 11 to detect the temperature of the dialysate. Both the temperature detection structure and the cooling structure 50 are connected to the control structure, which is configured to control the opening and closing of the cooling structure 50 based on the detection data from the temperature detection structure. In this way, the temperature detection structure can detect the dialysate temperature in real time, achieving real-time and accurate monitoring of the dialysate temperature. This provides staff with precise dialysate temperature data, allowing them to check and confirm whether the dialysis environment meets the requirements in real time, ensuring the reliability and safety of the dialysis apparatus. Simultaneously, the control structure connects the temperature detection structure and the cooling structure 50 into a complete intelligent closed-loop temperature control system. It can automatically and accurately control the opening and closing of the cooling structure 50 based on the difference between the real-time dialysate temperature and the set value, avoiding uncertainties in the dialysis environment caused by staff oversight, and improving the automation, repeatability, and dialysis success rate of the dialysis apparatus.
[0061] like Figure 1 and Figure 2As shown, the stirring structure 30 includes an interconnected connecting part and multiple stirring parts 31. The multiple stirring parts 31 are spaced apart around a second preset axis, and at least some of the stirring parts 31 are arc-shaped. The dialysis apparatus also includes a drive structure 80. The drive structure 80 is driven to the connecting part to drive the connecting part to rotate the stirring parts 31 around the second preset axis. In this way, the drive structure 80 can provide a stable and reliable power source for the stirring structure 30, reducing the labor intensity of the staff and improving the stirring continuity and uniformity of the stirring structure 30. At the same time, the stirring parts 31 are designed to be spaced apart around the second preset axis and are arc-shaped, which can generate a more uniform, gentle and efficient flow field. This can not only effectively disperse the concentration boundary layer around the dialysis bag to improve dialysis efficiency, but also avoid damage to fragile biomolecule samples caused by the shear force generated by violent stirring, thereby improving the stirring reliability and safety of the stirring structure 30 and further improving the dialysis reliability of the dialysis apparatus.
[0062] In this embodiment, the drive structure 80 is a motor.
[0063] In this embodiment, the second preset axis is aligned with the central axis of the motor's output shaft.
[0064] In this embodiment, the stirring structure 30 is located at the bottom of the fixed structure 20. This arrangement makes the structural positions of the stirring structure 30 and the fixed structure 20 more suitable, optimizing their installation space and achieving a compact and miniaturized design for the dialysis device. Simultaneously, this arrangement also allows the stirring structure 30 to drive the dialysate to generate a certain vortex, driving the dialysate through the second through-hole into the fixed cavity, forming a highly efficient circulating flow path throughout the entire fixed cavity, ensuring the continuity and smoothness of the dialysate flow.
[0065] Optionally, the second preset axis is set coaxially with the first preset axis.
[0066] Optionally, the second preset axis is set parallel to the first preset axis.
[0067] like Figure 2As shown, the dialysis apparatus also includes a timer 90, which is connected to the drive structure 80. The control structure is configured to control the start and stop of the drive structure 80 according to the preset time of the timer 90; and / or, an optocoupler isolation structure is connected to both the cooling structure 50 and the control structure. The control structure controls the opening and closing of the cooling structure 50 through the optocoupler isolation structure. In this way, the control structure can achieve programmed automatic control of the stirring process through the timer 90. Operators can preset the stirring time and intervals, achieving intermittent stirring of the dialysate without manual intervention, ensuring the continuity and reliability of dialysate stirring, and improving the convenience of the experiment. Simultaneously, the optocoupler isolation structure can electrically isolate the weak current of the control circuit from the strong current of the cooling structure 50, effectively preventing interference and fluctuations in the strong current circuit from impacting the precision control circuit, greatly improving the stability and reliability of the entire system operation.
[0068] In this embodiment, the optocoupler isolation structure is also connected to the heat dissipation structure, and the control structure can control the opening and closing of the heat dissipation structure through the optocoupler isolation structure.
[0069] In this embodiment, the connection between the control structure and the temperature detection structure and the cooling structure 50 is either an electrical connection or a signal connection.
[0070] Specifically, the control structure includes a microcontroller and a logic control module. The microcontroller can be an AT89S52 microcontroller with a built-in timer. An external power monitoring circuit is added to the chip, and the semiconductor cooling chip is powered by a 15V DC regulated power supply.
[0071] As can be seen from the above description, the embodiments of this utility model achieve the following technical effects:
[0072] The dialysis unit has a receiving cavity for holding the dialysate. A fixing structure is suspended within the receiving cavity. The fixing structure has a first through hole, a second through hole, and a fixing cavity. Both the first and second through holes communicate with the fixing cavity, allowing the fixing cavity to communicate with the receiving cavity through the first and second through holes. A stirring structure is movably disposed within the receiving cavity to stir the dialysate. A separating assembly is disposed within the fixing cavity. The separating assembly includes multiple separating structures spaced apart around a first preset axis to divide the fixing cavity into multiple sub-fixed cavities for holding the dialysate and dialysis bags. In this way, the operator places the fibrinogen sample to be dialyzed into a dialysis bag, and then places the dialysis bag into the fixing cavity of the fixing structure. This avoids the dialysis bag floating or sticking to the cavity wall within the receiving cavity, ensuring the stability of the dialysis bag placement and thus guaranteeing the reliability of the dialysis of the fibrinogen sample. This solves the problem of poor dialysis bag placement stability in existing dialysis units. Meanwhile, the fixing chamber of the fixed structure is connected to the receiving chamber through the first and second through holes, ensuring that the dialysate in the receiving chamber enters the fixing chamber through the first and second through holes. This further ensures contact between the dialysis bag and the dialysate, guaranteeing the reliability of dialysis for human fibrinogen samples. Simultaneously, the dialysis device can move within the receiving chamber via a stirring structure, achieving agitation of the dialysate. This replaces manual stirring by operators, reducing their workload and ensuring automated stirring of the dialysis device. This allows the dialysate to be stably and continuously agitated, ensuring the continuity and uniformity of dialysate flow. Furthermore, the arrangement of multiple partitions dividing the fixed chamber into multiple sub-fixed chambers increases the number of dialysis bags that the fixed structure can accommodate. This allows the fixed structure to simultaneously fix multiple dialysis bags, enabling simultaneous dialysis and ensuring the stability of multiple dialysis bags, thus improving the dialysis efficiency and reliability of the dialysis device.
[0073] It should be noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the exemplary embodiments according to this application. As used herein, the singular form is intended to include the plural form as well, unless the context clearly indicates otherwise. Furthermore, it should be understood that when the terms "comprising" and / or "including" are used in this specification, they indicate the presence of features, steps, operations, devices, components, and / or combinations thereof.
[0074] It should be noted that the terms "first," "second," etc., used in the specification, claims, and accompanying drawings of this application are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that such data can be interchanged where appropriate so that the embodiments of this application described herein can be implemented in sequences other than those illustrated or described herein.
[0075] The above description is merely a preferred embodiment of this utility model and is not intended to limit the utility model. Various modifications and variations can be made to this utility model by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.
Claims
1. A dialysis device, characterized in that, include: The box (10) has a receiving cavity (11) for holding the dialysate. A fixing structure (20) is suspended inside the receiving cavity (11). The fixing structure (20) has a first through hole, a second through hole and a fixing cavity. The first through hole and the second through hole are both connected to the fixing cavity so that the fixing cavity is connected to the receiving cavity (11) through the first through hole and the second through hole. A stirring structure (30) is movably disposed within the receiving cavity (11) to stir the dialysate; A partition assembly is disposed within the fixed cavity. The partition assembly includes a plurality of partition structures (40), which are spaced apart around a first preset axis to divide the fixed cavity into a plurality of sub-fixed cavities (21) for accommodating the dialysate and the dialysate bag.
2. The dialysis apparatus according to claim 1, characterized in that, The dialysis device also includes: A refrigeration structure (50) is provided with its refrigeration end (51) facing the cavity wall of the receiving cavity (11) to cool the dialysate; The housing (10) further includes a receiving cavity, and the refrigeration structure (50) is disposed within the receiving cavity, which is located outside the receiving cavity (11); and / or, The cooling end of the cooling structure (50) is attached to the cavity wall of the receiving cavity (11) to cool the dialysate; and / or, The cooling structure (50) is a semiconductor cooling structure.
3. The dialysis apparatus according to claim 2, characterized in that, The cooling structure includes: A heat dissipation structure is provided at the heat dissipation end (52) of the cooling structure (50) away from the receiving cavity (11) to dissipate heat from the heat dissipation end (52).
4. The dialysis apparatus according to claim 1, characterized in that, Each of the partition structures (40) has a first mating part, and the fixing structure (20) has a plurality of second mating parts (22), and the plurality of second mating parts (22) are provided in a one-to-one correspondence with the plurality of first mating parts; In this part, one of the first mating part and the second mating part (22) is a protrusion, and the other of the first mating part and the second mating part (22) is a recess. The protrusion extends into the recess to engage with the recess.
5. The dialysis apparatus according to claim 1, characterized in that, The dialysis device also includes a hanging structure (60), one end of which is connected to the fixed structure (20), and the other end of which is connected to the housing (10), so that the fixed structure (20) is suspended in the receiving cavity (11).
6. The dialysis apparatus according to claim 5, characterized in that, The mounting structure (60) is multiple, and the multiple mounting structures (60) are spaced apart around the first preset axis; and / or, The hanging structure is a hook.
7. The dialysis apparatus according to claim 1, characterized in that, The partition structure (40) is plate-shaped and has a third through hole, which is connected to the sub-fixed cavity (21). The third through hole is multiple, and the multiple third through holes are divided into multiple groups. Each group of the third through holes includes multiple third through holes. The multiple groups of the third through holes are spaced apart along the length direction of the partition structure (40), and the multiple third through holes in each group are spaced apart along the width direction of the partition structure (40).
8. The dialysis apparatus according to claim 2, characterized in that, The dialysis device also includes: The temperature control system (70) includes a temperature detection structure and a control structure. The temperature detection structure is disposed on the housing (10), and the detection part of the temperature detection structure extends into the receiving cavity to detect the temperature of the dialysate. Both the temperature detection structure and the cooling structure (50) are connected to the control structure, which is configured to control the opening and closing of the cooling structure (50) based on the detection data of the temperature detection structure.
9. The dialysis apparatus according to claim 8, characterized in that, The stirring structure (30) includes a connecting part and a plurality of stirring parts (31) connected to each other. The plurality of stirring parts (31) are arranged at intervals around a second preset axis. At least some of the stirring parts (31) are arranged in an arc shape. The dialysis device further includes: The driving structure (80) is driven to connect with the connecting part to drive the connecting part to drive the stirring part (31) to rotate around the second preset axis.
10. The dialysis apparatus according to claim 9, characterized in that, The dialysis device further includes a timer (90) connected to the drive structure (80), and the control structure is configured to control the start and stop of the drive structure (80) according to the preset time of the timer (90); And / or, The optocoupler isolation structure is connected to both the cooling structure (50) and the control structure. The control structure controls the opening and closing of the cooling structure (50) through the optocoupler isolation structure.