VACCINE FOR PROTECTION AGAINST LAWSONIA INTRACELLULARIS
Patent Information
- Authority / Receiving Office
- DK · DK
- Patent Type
- Patents
- Current Assignee / Owner
- INTERVET INT BV
- Filing Date
- 2009-04-16
- Publication Date
- 2026-06-29
AI Technical Summary
Current vaccines against Lawsonia intracellularis, an intracellular bacterium causing porcine proliferative enteropathy, are limited by the need for oral administration and the inefficacy of subunit or killed vaccines, with no effective systemic administration methods available, leading to insufficient protection and safety concerns.
A non-live carbohydrate-containing composition derived from killed Lawsonia intracellularis bacteria, suitable for systemic administration, which induces protective immunity comparable to live vaccines by incorporating whole cells of killed bacteria, offering improved safety and broader immune response.
The systemic administration of the carbohydrate-containing vaccine provides effective protection against Lawsonia intracellularis infection, matching or exceeding the protection of existing live vaccines while ensuring inherent safety, and can be combined with other antigens for enhanced efficacy.