Improved cosmetic composition for the treatment of human perspiration and body odor

Abstract

Improved cosmetic composition for the treatment of human perspiration and body odor. The present invention relates to a composition comprising, in a cosmetically acceptable aqueous medium, magnesium chloride, dipotassium phosphate, at least one anionic thickener selected from natural anionic gums, carrageenans, pectins, and phosphated starches, at least one modulating agent selected from mono- or polycarboxylic acids, optionally hydroxylated, in free or salted form, and at least one deodorizing active ingredient selected from a zinc salt, a bis(dihydropyridinyl)decan derivative, and mixtures thereof. It also relates to the associated process. Figure for abstract: none

Description

Title of the invention: Improved cosmetic composition for the TREATMENT OF HUMAN PERSPIRATION AND BODY ODORS

[0001] The present invention relates to an improved cosmetic composition useful for the treatment of human perspiration and body odors resulting from perspiration, as well as an associated cosmetic process.

[0002] The armpits, as well as certain other parts of the body, are generally the site of various discomforts that may or may not stem directly from perspiration. These discomforts often lead to unpleasant and embarrassing sensations, primarily due to the presence of sweat. This sweat can, in some cases, make the skin feel damp and wet clothing, particularly in the armpits or on the back, leaving visible marks. Furthermore, the presence of sweat can lead to the release of body odors, which are usually unpleasant. Such discomforts should be taken into account, even in cases of moderate perspiration.

[0003] In the cosmetic field, it is well known to use, in topical application, deodorant products containing substances which have the effect of masking, absorbing, improving and / or reducing the unpleasant odor resulting from the decomposition of human sweat and remedying the problems mentioned above.

[0004] Antiperspirant compositions, which generally include aluminum and / or zirconium hydrochlorides, are also available on the market as a replacement for aluminum salts, the harmfulness of which is now well established. These substances reduce perspiration flow by forming a plug in the sweat duct. However, using these substances at high concentrations to achieve good efficacy leads to formulation difficulties. Furthermore, it has been observed that the antiperspirant efficacy of these substances is limited when used alone.

[0005] To remedy all the disadvantages mentioned above, it has been proposed to search for other effective active substances that are well tolerated by the skin and easily formulate.

[0006] Among the approaches recently explored is that described in WO2019 / 072831: this application describes a cosmetic process for treating human perspiration and possibly body odor resulting from perspiration, which includes the use of at least one n-valent cation Xn+, at least one m-valent anion Ym, and at least one modulating agent. However, all The cations and anions described are not equivalent, and the galenic formulation as well as the treatment of body odors needed improvement.

[0007] There is therefore a real need for a cosmetic composition applied to the skin for the treatment of human perspiration that does not present all the drawbacks described above, namely, one that both reduces the flow of perspiration and provides a satisfactory deodorant effect. This cosmetic composition must also be well tolerated by the skin. Furthermore, such a cosmetic composition must include at least one effective antiperspirant and at least one deodorant agent, these agents being compatible with each other and within the same cosmetic composition. Finally, such a cosmetic composition for the treatment of human perspiration and body odor must be easy to formulate, non-irritating, and stable during storage.

[0008] The Applicant has discovered, surprisingly, that this objective can be achieved with an aqueous composition comprising, in particular, magnesium chloride (MgCl2), dipotassium phosphate (K2HPO4), and at least one deodorant active ingredient selected from a zinc salt, a bis(dihydropyridinyl)decan derivative, and mixtures thereof. The resulting composition is easy to formulate, stable, and exhibits antiperspirant and deodorant efficacy.

[0009] The present invention therefore relates to a composition comprising, in a cosmetically acceptable aqueous medium, magnesium chloride, dipotassium phosphate, at least one anionic thickener selected from natural anionic gums, carrageenans, pectins and phosphated starches, at least one modulating agent selected from mono- or polycarboxylic acids possibly hydroxylated, in free or salified form and at least one deodorant active selected from a zinc salt, a derivative of bis(dihydropyridinyl)decan and mixtures thereof.

[0010] By "cosmetically acceptable aqueous medium", we mean an aqueous medium compatible with the skin and / or its appendages or mucous membranes which has a pleasant colour, odor and feel and which does not generate discomforts (such as tightness) likely to deter the consumer from using this composition.

[0011] Said cosmetically acceptable medium is also a medium which does not leave traces when applied and thus does not stain clothes.

[0012] Said cosmetically acceptable medium is aqueous, i.e. comprises an aqueous phase.

[0013] The present invention also relates to a cosmetic process for treating human perspiration and body odors resulting from perspiration (hereinafter "process according to the invention"), comprising the application of a composition according to the invention to the skin.

[0014] The present invention also relates to a cosmetic process for treating human perspiration and body odors resulting from perspiration, which comprises:

[0015] (i) either the mixture just before use of at least one composition A and of less a composition B, said compositions A and B being packaged separately followed by the application of the resulting mixture to the skin surface;

[0016] (ii) either the simultaneous or sequential application to the skin surface of at least one composition A and at least one composition B packaged separately;

[0017] (iii) either the application to the skin surface of a composition comprising in the same support at least one composition A and at least one composition B; - said composition A comprising, in a cosmetically acceptable aqueous medium, at least magnesium chloride; - said composition B comprising, in a cosmetically acceptable aqueous medium, at least dipotassium phosphate; - said composition A and / or said composition B comprising an anionic thickener selected from natural anionic gums, carrageenans, pectins and phosphated starches; - said composition A and / or said composition B comprising a deodorant active ingredient selected from a zinc salt, a bis(dihydropyridinyl)decan derivative and mixtures thereof; and - said composition A and / or said composition B also comprising at least one modulating agent selected from mono- or polycarboxylic acids possibly hydroxylated, in free or salified form.

[0018] By "sequential", we mean a successive administration.

[0019] By "same support," it is meant that compositions A and B according to the invention are present in the same packaging, in particular a two-compartment packaging that allows the simultaneous application of compositions A and B. Composition

[0020] The composition according to the invention comprises, in a cosmetically acceptable aqueous medium, magnesium chloride, dipotassium phosphate, at least one anionic thickener selected from natural anionic gums, carrageenans, pectins and phosphated starches, at least one modulating agent selected from mono- or polycarboxylic acids, possibly hydroxylated, in free or salified form and at least one deodorant active selected from a zinc salt, a bis(dihydropyridinyl)decan derivative and mixtures thereof. Aqueous phase

[0021] The composition comprises an aqueous phase (also called a cosmetically acceptable aqueous medium). In particular, it is formulated as an aqueous gel.

[0022] The aqueous phase of the composition contains water and, optionally, other solvents soluble or miscible in water. The solvents soluble or miscible in water include short-chain monoalcohols, for example in the Ci-C4 group, such as ethanol, isopropanol; diols or polyols such as ethylene glycol, 1,2-propylene glycol, 1,3-butylene glycol, hexylene glycol, diethylene glycol, dipropylene glycol, 2-ethoxyethanol, diethylene glycol monomethyl ether, triethylene glycol monomethyl ether and sorbitol, preferably 1,2-propylene glycol.

[0023] According to one embodiment, the composition comprises from 1% to 30% by weight of solvent(s) soluble or miscible in water relative to the total weight of the composition, preferably from 2% to 25% by weight, preferably from 4% to 22% by weight.

[0024] Preferably, the composition comprises at least 50% by weight of water relative to the total weight of the composition, preferably at least 55% by weight, preferably at least 70% by weight. Preferably, the composition comprises from 50% to 95% by weight of water relative to the total weight of the composition, preferably from 55% to 90% by weight, preferably from 65% to 85% by weight. Magnesium chloride (MgCl2)

[0025] Magnesium chloride (MgCl2) is a water-soluble salt. For the purposes of the present invention, "water-soluble salt" means any salt which, after being completely dissolved under stirring at a concentration of 0.5% in a water solution at a temperature of 25 °C, results in a solution containing less than 0.05% by weight of insoluble salt. Magnesium chloride (MgCl2) includes, in particular, the Mg2+ cation.

[0026] The composition according to the invention comprises an aqueous phase and preferably has a pH between 2 and 6, preferably between 4 and 6. If necessary, the pH is adjusted with a cosmetically acceptable acid or base, organic or mineral. Such an acid and such a base are those conventionally used in cosmetics.

[0027] Preferably, the composition comprises magnesium chloride in a content of between 1 and 30% by weight relative to the total weight of the composition, preferably between 3 and 25% by weight, preferably between 5 and 20% by weight. Dipotassium phosphate (K2HPO4)

[0028] The composition according to the invention also comprises dipotassium phosphate (K2HPO4). This dipotassium phosphate (K2HPO4) is also a water-soluble salt. Dipotassium phosphate (K2HPO4) includes, in particular, the HPO42 anion.

[0029] Preferably, the composition comprises dipotassium phosphate (K2HPO4) in a content of between 1 and 25% by weight relative to the total weight of the composition, preferably between 3 and 20% by weight, preferably between 5 and 15% by weight.

[0030] The weight ratio between magnesium chloride and dipotassium phosphate varies preferably from 3:1 to 1:1, preferably from 2:1 to 1:1, and more preferably from 1.5:1 to 1:1.

[0031] The total concentration of magnesium chloride and dipotassium phosphate varies preferably from 7 to 40% by weight, preferably between 10 and 30% by weight, and more preferably from 15 to 25% by weight relative to the total weight of composition. Modulating agent

[0032] The composition according to the invention comprises at least one modulating agent selected from mono- or polycarboxylic acids, possibly hydroxylated, in free or salified form.

[0033] Preferably, the polycarboxylic acids are chosen from among the di- and tricarboxylic acids, possibly hydroxylated. Such hydroxylated carboxylic acids are also called hydroxy acids.

[0034] Preferably, the modulating agent is chosen from propionic acid, citric acid, tartaric acid, lactic acid, malic acid, succinic acid, glutaric acid, itaconic acid and mixtures thereof, in free or salted form.

[0035] Preferably, the modulating agent is chosen from tricarboxylic acids, possibly hydroxylated, preferably from hydroxylated tricarboxylic acids.

[0036] Mono- or polycarboxylic acids possibly hydroxylated are present in the composition in free form or in salified form.

[0037] When they are present in salified form, they may be present as an alkali metal salt or an alkaline earth metal salt, preferably as a sodium or potassium salt.

[0038] Preferably, the modulating agent is a mixture of a tricarboxylic acid possibly hydroxylated in free form and a tricarboxylic acid possibly hydroxylated in salified form.

[0039] Preferably, the modulating agent is a mixture of a hydroxylated tricarboxylic acid in free form and a hydroxylated tricarboxylic acid in salified form.

[0040] Preferably, the modulating agent is a mixture of citric acid and sodium citrate.

[0041] Preferably, the modulating agent is present in the composition at a content of between 0.1 and 10% by weight relative to the total weight of the composition, preferably between 0.5 and 5% by weight, preferably between 1 and 4% by weight. Anionic thickener

[0042] The composition according to the invention comprises an anionic thickener selected from natural anionic gums, carrageenans, pectins, and phosphated starches. Natural anionic gums include, in particular, xanthan gum, dehydroxanthan gum, and gellan gum.

[0043] Xanthan gum is a heteropolysaccharide produced on an industrial scale by the aerobic fermentation of the bacterium Xanthomonas campestris. Its structure consists of a main chain of [3-D-glucoses] linked in a [3(1,4)] fashion, similar to cellulose. Every other glucose molecule carries a trisaccharide side chain composed of an α-D-mannose, a [3-D-glucuronic acid], and a terminal [3-D-mannose]. The internal mannose residue is generally acetylated at carbon 6. Approximately 30% of the terminal mannose residues bear a pyruvate group linked in a chelated form between carbons 4 and 6. The charged glucuronic and pyruvic acids are ionizable, and therefore responsible for the anionic nature of xanthan gum (negative charge up to pH 1).

[0044] Xanthan gums have a molecular weight between 1,000,000 and 50,000,000.

[0045] Xanthan gums are represented for example by the products sold under the names Rhodicare by the company RHODIA CHIMIE, under the name SATIAXA E by the company Cargill Texturizing Solutions (for the food, cosmetic and pharmaceutical industries), under the name NOVAXAN by the company ADM, and under the names Kelzan and Keltrol by the company CP-Kelco.

[0046] The anionic thickener can also be a xanthan derivative, of the dehydroxanthan type.

[0047] Gellan gum is a linear anionic heteropolysaccharide based on oligoside units composed of 4 monosaccharides (tetrasaccharide). D-glucose, L-rhamnose and D-glucuronic acid in a 2:1:1 ratio are present in gellan gum as monomeric components.

[0048] For example, it is sold under the name KELCOGEL CG LA by the company CP KELCO.

[0049] Carrageenans are anionic polysaccharides constituting the cell walls of various red algae (Rhodophyceae) belonging to the families Gigartinaceae, Hypneaceae, Furcellariaceae, and Polyideaceae. They are generally obtained by hot aqueous extraction from natural strains of said algae. These linear polymers, formed by disaccharide motifs, are composed of two D-galactopyranoses linked alternately by α(1,3) and [3(1,4)] bonds. They are highly sulfated polysaccharides (20–50%), and the αD-galactopyranosyl residues may be in the 3,6-anhydro form. Depending on the number and the Based on the position of the ester-sulfate groups on the repeating disaccharide of the molecule, several types of carrageenan are distinguished: kappa-carrageenan, which has one ester-sulfate group; iota-carrageenan, which has two ester-sulfate groups; and lambda-carrageenan, which has three ester-sulfate groups. Carrageenan is composed primarily of potassium, sodium, magnesium, triethanolamine, and / or calcium salts, and sulfate esters of polysaccharides.

[0050] Carrageenans are marketed in particular by the company Seppic under the name Solagum®, by the company Gelymar under the name Carragel®, Carralact®, and Carrasol®, by the company Cargill, under the names SATIAGEL and SATIAGUM, and by the company CP-Kelco under the name GENULACTA®, GENUGEL® and GENUVISCO®.

[0051] Pectins are linear polymers of α-D-galacturonic acid (at least 65%) linked at positions 1 and 4, with a certain proportion of carboxyl groups esterified with a methanol group. Approximately 20% of the sugars constituting the pectin molecule are neutral sugars (L-rhamnose, D-glucose, D-galactose, L-arabinose, D-xylose). L-rhamnose residues are found in all pectins, integrated into the main chain at positions 1 and 2. Uronic acid molecules possess carboxyl groups. This function gives pectins the ability to exchange ions when these are in the -COO- form.

[0052] The anionic thickener can also be a phosphated starch. In particular, mono-starch phosphates (of the type Am-O-PO-(OX)-O-Am), distarch phosphates (of the type Am-O-PO-(OX)-O-Am), or even tri-starch (of the type Am-O-PO-(OX)-Am), or mixtures thereof, can be obtained by cross-linking starch with phosphorus compounds. Am designates starch, and X designates, in particular, alkali metals (for example, sodium or potassium), alkaline earth metals (for example, calcium, magnesium), ammonia salts, amine salts such as those of monoethanolamine, diethanolamine, triethanolamine, 3-aminopropanediol-1,2, and ammonium salts derived from basic amino acids such as lysine, arginine, sarcosine, omithine, or citrulline. In particular, phosphated starch is hydroxypropyl starch phosphate, marketed under the name Structure XL by Nouryon.

[0053] Preferably, the anionic thickener according to the invention is xanthan gum.

[0054] The anionic thickener, preferably xanthan gum, is present in the composition at a content of between 0.1 and 7% by weight relative to the total weight of the composition, preferably between 0.5 and 5% by weight, preferably between 0.8 and 2% by weight. Deodorant active ingredient

[0055] The composition according to the invention comprises a deodorant active ingredient selected from a zinc salt, a derivative of bis(dihydropyridinyl)decan and mixtures thereof.

[0056] For the purposes of this invention, "deodorant active ingredient" means any active ingredient that masks, absorbs, improves, and / or reduces the unpleasant odor resulting from the decomposition of human sweat when present in the composition according to the invention. Preferably, for the purposes of this invention, "deodorant active ingredient" means any active ingredient that masks, absorbs, improves, and / or reduces the unpleasant odor resulting from the decomposition of human sweat by synergistically with the other components of the composition according to the invention.

[0057] According to one embodiment of the invention, the deodorant active ingredient is a zinc salt, preferably a zinc salt selected from zinc oxide, zinc acetate, zinc gluconate, zinc pyrithione, zinc PCA or zinc salt of pyrrolidone carboxylic acid, zinc sulfate, zinc chloride, a zinc dicarboxylate salt of a fatty acid and a polyquaterial compound and mixtures thereof.

[0058] According to a preferred embodiment of the invention, the deodorant active ingredient is a zinc salt selected from zinc gluconate, zinc PCA or zinc salt of pyrrolidone carboxylic acid, a zinc dicarboxylate salt of a fatty acid and a polyquaterial compound and mixtures thereof.

[0059] More preferably, the deodorant active ingredient is a zinc dicarboxylate salt of a fatty acid and a polyquaterial compound, in particular a zinc dicarboxylate salt of a fatty acid having 6 to 18 carbon atoms and a polyquaterial compound, and more particularly a zinc neodecanoate.

[0060] Quite surprisingly, the inventors of the present application have discovered that the combination of antiperspirant actives such as magnesium chloride and dipotassium phosphate, a modulator and a zinc salt as described above makes it possible, through synergistic action, to obtain compositions for the treatment of human perspiration and body odors resulting from perspiration.

[0061] According to another embodiment of the invention, the deodorant active ingredient is octenidine hydrochloride, also called N,N'-(l,10-Decanediyldi-l(4H)-py ridinyl-4-ylidene)bis-l-octanamine hydrochloride.

[0062] Preferably, the deodorant active ingredient is present in the composition at a concentration of between 0.05 and 5% by weight relative to the total weight of the composition, preferably between 0.08 and 3% by weight relative to the total weight of the composition, and more preferably between 0.1 and 1% by weight relative to the total weight of the composition. Preservatives and other additives

[0063] The composition according to the invention may include at least one preservative and / or at least one additive.

[0064] Among the preservatives, we can mention in particular phenoxyethanol, caprylyl glycol, benzyl alcohol and their mixtures.

[0065] Preferably, the composition according to the invention is substantially free of caprylyl glycol. By substantially free of caprylyl glycol, it is understood that the composition comprises less than 0.3% by weight, preferably less than 0.1% by weight relative to the total weight of the composition, of caprylyl glycol. Preferably, the composition according to the invention is completely free of caprylyl glycol.

[0066] Preferably, the composition according to the invention comprises at least phenoxyethanol.

[0067] Preferably, the preservative is present in the composition at a level of between 0.05 and 5% by weight relative to the total weight of the composition, preferably between 0.08 and 3% by weight relative to the total weight of the composition, more preferably from 0.1 to 1% by weight relative to the total weight of the composition.

[0068] The additive can be any usual additive in the cosmetic field, such as for example a perfume or a filler.

[0069] Preferably, the composition according to the invention comprises, in a cosmetically acceptable aqueous medium, by weight relative to the total weight of the composition:

[0070] at least 55% by weight of water;

[0071] of magnesium chloride in a content of between 1 and 30% by weight relative to the total weight of composition, preferably between 3 and 25% by weight, preferably between 5 and 20% by weight;

[0072] dipotassium phosphate in a content of between 1 and 25%, preferably between 3 and 20% by weight, preferably between 5 and 15% by weight;

[0073] between 0.05 and 5% by weight of a zinc salt or a derivative of bis(dihydropyridinyl)decan, preferably between 0.08 and 3% by weight, preferably between 0.1 and 1% by weight;

[0074] possibly at least one preservative, preferably phenoxyethanol;

[0075] between 0.1 and 5% by weight of citric acid, preferably between 0.5 and 4% by weight, preferably between 1 and 3% by weight;

[0076] between 0.05 and 5% by weight of sodium citrate, preferably between 0.1 and 3% by weight, preferably between 0.5 and 2% by weight; and

[0077] between 0.1 and 7% by weight, preferably between 0.5 and 5% by weight, preferably between 0.8 and 2% by weight of xanthan gum. Application method

[0078] The present invention also relates to a cosmetic process for treating human perspiration and body odors resulting from perspiration (i- after "process according to the invention"), comprising the application of a composition according to the invention to the skin.

[0079] The present invention also relates to a cosmetic process for treating human perspiration and possibly body odors resulting from perspiration (hereinafter "process 2 according to the invention"), which comprises:

[0080] (i) either the mixture just before use of at least one composition A and of less a composition B, said compositions A and B being packaged separately followed by the application of the resulting mixture to the skin surface;

[0081] (ii) either the simultaneous or sequential application to the skin surface of at least one composition A and at least one composition B packaged separately;

[0082] (iii) either the application to the skin surface of a composition comprising in the same support at least one composition A and at least one composition B; - said composition A comprising, in a cosmetically acceptable aqueous medium, at least magnesium chloride; - said composition B comprising, in a cosmetically acceptable aqueous medium, at least dipotassium phosphate; - said composition A and / or said composition B comprising an anionic thickener selected from natural anionic gums, carrageenans, pectins and phosphated starches; - said composition A and / or said composition B comprising a deodorant active ingredient selected from a zinc salt and / or a derivative of bis(dihydropyridinyl)decan; and - said composition A and / or said composition B also comprising at least one modulating agent chosen from mono- or polycarboxylic acids possibly hydroxylated, in free or salified form.

[0083] To obtain an anti-perspirant effect on the skin, according to a first variant of the method 2 according to the invention (embody (i)), composition A and composition B are packaged separately and are mixed just before use (extemporaneous mixing) and then the mixture thus obtained is applied to the surface of the skin to be treated.

[0084] According to a second embodiment of method 2 of the invention (embody (ii)), composition A and composition B are packaged separately and applied simultaneously or sequentially to the skin surface to be treated. According to this embodiment, when compositions A and B are applied sequentially, the time interval between the application of composition A and the application of B can vary from 1 second to 24 hours, more preferably from 10 seconds to 24 hours, and even more preferably from 1 minute to 1 hour.

[0085] According to a third variant of the method 2 according to the invention (embody (iii)), a composition comprising composition A and composition B in the same support is applied directly to the skin surface. In this embodiment (iii), compositions A and B may, for example, be packaged in a device comprising at least two compartments containing composition A and composition B respectively, such as a twin tube, a two-compartment pump bottle, an aerosol device comprising two compartments which may include one or more outlet orifices (single-nozzle or double-nozzle), a device with a perforated wall such as a grid comprising two compartments; a device comprising two compartments each equipped with a rollerball applicator (multi-ball roll-on); a double stick.

[0086] Preferably, compositions A and B are applied sequentially and, even more preferably, composition B (comprising dipotassium phosphate) is applied first.

[0087] Preferably, the invention also relates to a cosmetic treatment method for human perspiration, and possibly for body odors associated with human perspiration, comprising applying to the skin surface, in particular to the surface of the armpits, an effective amount of composition A and an effective amount of composition B.

[0088] The application time of composition A and / or B on the skin surface may vary from 0.5 to 10 seconds, preferably from 1 to 5 seconds. Compositions A and B may be applied repeatedly to the skin surface. They may be applied repeatedly, over one day or over several days.

[0089] Preferably, the invention also relates to a cosmetic treatment method for human perspiration and body odors associated with human perspiration, comprising a first step of applying composition B to the skin surface, in particular to the surface of the armpits, and then a second step of applying composition A to the same surface. Galenic Forms

[0090] The composition according to the invention can be presented in all the galenic forms classically used for topical application and in particular in the form of aqueous or hydroalcoholic gels, or even in the form of aqueous sticks (i.e. solids).

[0091] Preferably, it is presented in the form of an aqueous gel or an aqueous stick (i.e. solid).

[0092] It can also, by the addition of a fatty or oily phase, be presented in the form of lotion-type dispersions, milk-type emulsions of liquid or semi-liquid consistency, obtained by dispersing a fatty phase in an aqueous phase (O / W) or vice versa (W / O), or suspensions or emulsions of soft, semi-solid consistency or solids such as creams or gels, or multiple emulsions (W / O / W or W / O / O), microemulsions, ionic and / or non-ionic vesicular dispersions, or wax / aqueous phase dispersions. These compositions are prepared according to standard methods.

[0093] The composition may be, in particular, packaged in pressurized form in an aerosol device or in a pump bottle; packaged in a device with a perforated wall, in particular a grid; packaged in a device with a roll-on applicator; packaged in the form of sticks, in the form of loose or compacted powder. It contains, in this respect, the ingredients generally used in this type of product and well known to those skilled in the art.

[0094] According to another particular embodiment of the invention, the composition can be solid, in particular in the form of a rod or stick; in the form of a loose or compacted powder.

[0095] By "solid composition", it is understood that the measurement of the maximum force measured in texture analysis when a probe is inserted into the formula sample must be at least equal to 0.25 Newtons, in particular at least equal to 0.30 Newtons, especially at least equal to 0.35 Newtons, assessed under precise measurement conditions as follows:

[0096] The formulas are hot-poured into pots 4 cm in diameter and 3 cm deep. Cooling is carried out at room temperature. The hardness of the prepared formulas is measured after 24 hours. The pots containing the samples are characterized by texturometric analysis using a texturometer such as the one marketed by Rhéo TA-XT2, according to the following protocol: a 5 mm diameter stainless steel ball probe is brought into contact with the sample at a speed of 1 mm / s. The measuring system detects the interface with the sample with a detection threshold of 0.005 newtons. The probe penetrates 0.3 mm into the sample at a speed of 0.1 mm / s. The measuring device records the evolution of the measured compressive force over time during the penetration phase. The hardness of the sample corresponds to the average of the maximum values ​​of the force detected during penetration, over at least 3 measurements.

[0097] The composition may also include at least one additional deodorant active ingredient and / or at least one additional deodorant antiperspirant active ingredient.

[0098] By way of illustration of these additional deodorant actives, bacteriostatic or bactericidal agents acting on axillary odor germs may be cited, such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (Triclosan), 2,4-dichloro-2'-hydroxydiphenyl ether, 3',4',5'-trichlorosalicylanilide, l-(3',4'-dichlorophenyl)-3-(4'-chlorophenyl)urea (Triclocarban) or 3,7,11-trimethyldodec α-2,5,10-trienol (Farnesol); quaternary ammonium salts such as cetyltrimethylammonium salts, cetylpyridinium salts; polyols such as those of the type glycerin, 1,3-propanediol (ZEMEA PROPANEDIOL® marketed by Dupont Tate and Lyle Bioproducts), 1,2-decanediol (Symclariol® from Symrise); glycerin derivatives such as Caprylic / Capric Glycerides (CAPMUL MCM® from Abitec), Glycerol Caprylate or Caprate (DERMOSOFT GMCY® and DERMOSOFT GMC® respectively from STRAETMANS), Polyglyceryl-2 Caprate (DERMOSOFT DGMC® from STRAETMANS), biguanide derivatives such as polyhexamethylene biguanide salts; chlorhexidine and its salts; 4-Phenyl-4,4-dimethyl-2-butanol (SYMDEO MPP® from Symrise); cyclodextrins; alum or capryloyl salicylic acid or 2-hydroxy-5-(l-oxooctyl)benzoic acid).

[0099] The deodorant actives may preferably be present in the compositions according to the invention in weight concentrations ranging from 0.01 to 10% by weight relative to the total weight of the composition.

[0100] By way of illustration of additional deodorant antiperspirant actives, the following may be cited in particular: antiperspirant salts or complexes of aluminium and / or zirconium, preferably chosen from aluminium halohydrates; aluminium and zirconium halohydrates, zirconium hydroxychloride and aluminium hydroxychloride complexes with or without an amino acid such as those described in US patent 3792068.

[0101] Among aluminium salts, particular examples include aluminium hydrochloride in activated or inactivated form, aluminium chlorohydrex, aluminium chlorohydrex polyethylene glycol complex, aluminium chlorohydrex propylene glycol complex, aluminium dichlorohydrate, aluminium dichlorohydrex polyethylene glycol complex, aluminium dichlorohydrex propylene glycol complex, aluminium sesquichlorohydrate, aluminium sesquichlorohydrex polyethylene glycol complex, aluminium sesquichlorohydrex propylene glycol complex, aluminium sulfate buffered by sodium aluminium lactate.

[0102] Among the aluminium and zirconium salts, particular examples include aluminium zirconium octachlorohydrate, aluminium zirconium pentachlorohydrate, aluminium zirconium tetrachlorohydrate, aluminium zirconium trichlorohydrate.

[0103] Zirconium hydroxychloride and aluminum hydroxychloride complexes with an amino acid are generally known as ZAG (when the amino acid is glycine). Examples of these products include aluminum zirconium octachlorohydrex glycine, aluminum zirconium pentachlorohydrex glycine, aluminum zirconium tetrachlorohydrex glycine, and aluminum zirconium trichlorohydrex glycine.

[0104] Aluminium sesquichlorohydrate is notably sold under the trade name REACH 301® by the company SUMMITREHEIS.

[0105] Among aluminium and zirconium salts, we can mention zirconium hydroxychloride and aluminium hydroxychloride complexes with an amino acid such as glycine having the INCI name: ALUMINUM ZIRCONIUM TETRACHLOROHYDREX GLY for example that marketed under the name REACH AZP-908-SUF® by the company SUMMITREHEIS.

[0106] Aluminium chlorohydrate will be used in particular in activated or non-activated form under the trade names LOCRON S FLA®, LOCRON P, LOCRON L.ZA by the company CLARIANT; under the trade names MICRODRY ALUMINUM CHLOROHYDRATE®, MICRO-DRY 323®, CHLORHYDROL 50, REACH 103, REACH 501 by the company SUMMITREHEIS; under the trade name WESTCHLOR 200® by the company WESTWOOD; under the trade name ALOXICOLL PF 40® by the company GUILINI CHEMIE; CLURON 50%® by the company INDUSTRIA QUIMICA DEL CENTRO; CLOROHIDROXIDO ALUMINIO SO A 50%® by the company FINQUIMICA. Another example of an antiperspirant active ingredient is expanded perlite particles such as those obtained by the expansion process described in US patent 5,002,698.

[0107] Preferably, the composition comprises less than 5% by weight of aluminum and / or zirconium salts, preferably less than 3% by weight, preferably less than 1% by weight. Preferably, it is completely free of aluminum and zirconium salts.

[0108] Throughout the description, including the claims, the expression "comprising one" shall be understood as synonymous with "comprising at least one", unless otherwise specified.

[0109] The expressions "between ... and ..." and "ranging from ... to ..." should be understood inclusive of bounds, unless otherwise specified.

[0110] In the description and examples, unless otherwise stated, percentages are weight percentages. Percentages are therefore expressed as a percentage of the total weight of the composition (% w / w). Temperature is expressed in degrees Celsius unless otherwise stated, and pressure is atmospheric pressure unless otherwise stated.

[0111] The invention is illustrated in more detail by the non-limiting examples presented below. Examples Example 1 Zinc-based formulations

[0112] Compositions A1 and A2 are prepared by mixing in water the following compounds listed in order of introduction: citric acid, sodium citrate, MgCl2, xanthan gum, zinc neodecanoate (composition A2 only) and finally phenoxyethanol.

[0113] [Tables 1] Ingredients Al (% w / w) A2 (% w / w) Citric acid (13) 0.017 0.017 Sodium citrate (3) 1.44 1.44 Magnesium chloride (MgCl2)(9) 20 20 Xanthan gum (5) 1 1 Zinc neodecanoate (10) - 0.2 Phenoxyethanol(1) 0.5 0.5 Water QsplOO QsplOO

[0114] Compositions B1 and B2 are prepared by mixing the following compounds in water, listed in order of introduction: citric acid, KH2PO4, xanthan gum, zinc neodecanoate (composition B2 only) and finally phenoxyethanol.

[0115] [Tables2] Ingredients B1 (% w / w) B2 (% w / w) Citric acid (8) 3 3 Dipotassium phosphate (K2HPO4) (4) 17.2 17.2 Xanthan gum (5) 1 1 Zinc neodecanoate (10) - 0.2 Phenoxyethanol (1) 0.5 0.5 Water QsplOO QsplOO

[0116] Then the formulations Fl (comparative) and F2 (invention) are obtained by introducing respectively the compositions B1 and B2 into the compositions Al and A2 under magnetic stirring (in other words, the formulation F2 therefore comprises the compositions A2 and B2).

[0117] The comparative formulation C2 is prepared by mixing in water the following compounds listed in order of introduction: xanthan gum then Zinc neodecanoate.

[0118] [Tables3] Ingredients C2 (% w / w) Xanthan gum (5) 1 Zinc neodecanoate (10) 0.2 Phenoxyethanol (1) 0.5 Water QsplOO

[0119] The complete formulations obtained according to the protocols detailed above are given in Table 4 below.

[0120] [Tables4] Formulations Fl (% w / w) Comparative C2 (% w / w) Comparative F2 (% w / w) Invention Phenoxyethanol (i) 0.50 0.50 0.50 Water (2) 77.77 98.30 77.47 Sodium citrate (3) 0.72 - 0.72 k2hPO4 (4) 8.60 - 8.60 Xanthan gum (5) 0.90 1.00 1.00 Citric acid (6' 1.51 - 1.51 MgCl2 (7' 10.00 - 10.00 Zinc neodecanoate (8' - 0.20 0.20

[0121] (1) sold under the trade name SEPICIDE LD by the company SEPPIC

[0122] (2)Biologically clean deionized water

[0123] (3) sold under the trade name TRISODIUM CITRATE DIHYDRATE FINE F 6000 by the company JUNGBUNZLAUER

[0124] (4) sold under the trade name DIPOTASSIUM HYDROGEN PHOSPHATE ANHYDROUS (CHEMICAL REAGENT GRADE) by JIANGSU KOLOD FOOD INGREDIENTS

[0125] (5) sold under the trade name KELTROL CG by the company CP KELCO

[0126] (6 ' sold under the trade name CITRIC ACID MONOHYDRATE by the company CITURGIA BIOCHEMICALS

[0127] (7 ' sold under the trade name MAGNESIUM CHLORIDE HEXA- HYDRATE by the company DR PAUL LOHMANN

[0128] (8' sold under the trade name ZINC NEODECANOATE by the SIGMA ALDRICH company

[0129] It has been found that zinc salts, in particular zinc neodecanoate in compositions A2 and B2, but also zinc gluconate and zinc PCA in equivalent formulations not shown in Table 4, are excellent candidates as deodorant actives due to their compatibility with the other compounds in said compositions A2 and B2. Compositions A2 and B2 exhibit, in particular and by way of example, excellent stability at room temperature at 1 month and at 2 months. Evaluation of antibacterial performance

[0130] The evaluation of the antimicrobial properties of formulations Fl, F2 and C2 is carried out according to the following protocol:

[0131] In summary, in a suitable culture medium, the biocidal effect of the formulas is evaluated on the strains of interest after 2h, 6h and 24h of contact compared with a placebo (i.e. medium without formula). At each contact time, the logarithmic reduction in the number of viable strains is measured.

[0132] The model strain for "axillary odor" is:

[0133] Corynebacterium freneyi CIP 52.16 (formerly Corynebacterium xerosis)

[0134] This strain is brought into contact with the formula to be tested in a culture medium in the following proportions:

[0135] - 10% of the inoculum at 10⁸ germs / ml,

[0136] - 10% of the formula to be tested, and

[0137] - 80% culture medium (Trypcase Soy broth).

[0138] In parallel, a growth control, in which the formula is replaced by a diluent, is prepared under the same conditions.

[0139] The samples are placed in an incubator at a temperature of 35°C (optimal growth temperature for the strain) with continuous agitation during the test.

[0140] After 2, 6 and 24 hours of contact time, the number of viable microorganisms remaining in the mixture is evaluated.

[0141] The results are expressed as the logarithm of the number of microorganisms per millilitre of mixture.

[0142] The result obtained with the formula to be tested is compared to the results of the growth control and the difference is expressed as a number of Log difference at T 24 hours.

[0143] The count (Log CFU / ml) at 24h for each of the formulations detailed in Table 4 is shown in Table 5 below.

[0144] [Tables5] 24-hour count (Log CFU / ml) Control 8.4 Fl (comparative) 8.1 C2 (comparative) 7.9 F2 (invention) 5.7

[0145] It appears that the antimicrobial activity of formulation F2 according to the invention is significantly improved compared to other formulations, in particular compared to formulation C2, demonstrating a synergy of the combination of the antiperspirant Fl formulation and Zinc neodecanoate (-2.7 Log at 24h compared to the control).

[0146] Thus, only formula F2 according to the invention exhibits very good antimicrobial activity. Example 2 Formulation based on octenidine HCl

[0147] The gel formulas below were prepared by mixing in water. Formula FO is according to the invention, while formula Fl, identical to Example 1, is comparative. Formula FO is obtained by introducing a composition BO, identical to composition B1 of Example 1 but comprising 0.4% w / w octenidine HCl, into a composition AO, identical to composition B1 of Example 1, under magnetic stirring.

[0148] Compositions AO and BO exhibit excellent stability at room temperature at 1 month and at 2 months.

[0149] [Tableauxô] Formulations Fl (% w / w) FO (% w / w) Phenoxyethanol(1) 0.50 0.50 Water (2) 77.77 77.47 Sodium citrate (3) 0.72 0.72 K2HPO4 (4) 8.60 8.60 Xanthan gum (5) 0.90 1.00 Citric acid (6' 1.51 1.51 MgCl2 (7' 10.00 10.00 Octenidine HCl (9' - 0.20

[0150] (1) sold under the trade name SEPICIDE LD by the company SEPPIC

[0151] (2)biologically clean deionized water

[0152] (3) sold under the trade name TRISODIUM CITRATE DIHYDRATE FINE F 6000 by the company JUNGBUNZLAUER

[0153] (4) sold under the trade name DIPOTASSIUM HYDROGEN ANHYDROUS PHOSPHATE (CHEMICAL REAGENT GRADE) by JIANGSU KOLOD FOOD INGREDIENTS

[0154] (5) sold under the trade name KELTROL CG by the company CP KELCO and RHODIACARE XC - (OUVRICARE XC) by the company PMC OUVRIE

[0155] (6) sold under the trade name CITRIC ACID MONOHYDRATE by the company CITURGIA BIOCHEMICALS

[0156] (7) sold under the trade name MAGNESIUM CHLORIDE HEXA- HYDRATE by the company DR PAUL LOHMANN

[0157] (9) sold under the trade name OCTENIDINE HYDROCHLORIDE by INTERCHIM Evaluation of antibacterial performance

[0158] The evaluation of the antimicrobial properties of the Fl and FO formulations is carried out according to the same protocol as that of example 1.

[0159] The count (Log CFU / ml) at 24h for each of the formulations is shown in Table 7 below.

[0160] [Tables7] 24-hour count (Log CFU / ml) Control 8.4 Fl (comparative) 8.1 FO (invention) 3.3

[0161] It appears that the antimicrobial activity of the FO formulation according to the invention is significantly improved compared to that of the Fl formulation (-4.8 Log at 24h).

[0162] The FO formula according to the invention thus exhibits very good antimicrobial activity.

Claims

Demands

1. Composition comprising, in a cosmetically acceptable aqueous medium, magnesium chloride, dipotassium phosphate, at least one anionic thickener selected from natural anionic gums, carrageenans, pectins and phosphated starches, at least one modulating agent selected from mono- or polycarboxylic acids, possibly hydroxylated, in free or salified form and at least one deodorant active selected from a zinc salt, a bis(dihydropyridinyl)decan derivative and mixtures thereof.

2. Composition according to claim 1, characterized in that it comprises magnesium chloride in a content of between 1 and 30% by weight relative to the total weight of composition, preferably between 3 and 25% by weight, preferably between 5 and 20% by weight.

3. Composition according to claim 1 or 2, characterized in that it comprises dipotassium phosphate in a content of between 1 and 25% by weight relative to the total weight of composition, preferably between 3 and 20% by weight, preferably between 5 and 15% by weight.

4. Composition according to any one of the preceding claims, characterized in that the weight ratio between magnesium chloride and dipotassium phosphate varies from 3:1 to 1:1, preferably from 2:1 to 1:1, and more preferably from 1.5:1 to 1:

1.

5. Composition according to any one of the preceding claims, characterized in that the modulating agent is selected from propionic acid, citric acid, tartaric acid, lactic acid, malic acid, succinic acid, glutaric acid, itaconic acid and mixtures thereof, in free or salted form.

6. Composition according to any one of the preceding claims, characterized in that the modulating agent is a mixture of a hydroxylated tricarboxylic acid in free form and a hydroxylated tricarboxylic acid in salified form.

7. Composition according to any one of the preceding claims, characterized in that the modulating agent is a mixture of citric acid and sodium citrate.

8. Composition according to any one of the preceding claims, characterized in that the modulating agent is present in the composition in one content between 0.1 and 10% by weight relative to the total weight of composition, preferably between 0.5 and 5% by weight, preferably between 1 and 4% by weight.

9. Composition according to any one of the preceding claims, characterized in that the anionic thickener is selected from xanthan gum, dehydroxanthan gum and gellan gum, preferably xanthan gum.

10. Composition according to any one of the preceding claims, characterized in that the anionic thickener is present in the composition in a content of between 0.1 and 7% by weight relative to the total weight of the composition, preferably between 0.5 and 5% by weight, preferably between 0.8 and 2% by weight.

11. Composition according to any one of the preceding claims, characterized in that the deodorant active is a zinc salt, preferably selected from zinc oxide, zinc acetate, zinc gluconate, zinc pyrithione, zinc PCA or zinc salt of pyrrolidone carboxylic acid, zinc sulfate, zinc chloride, a zinc dicarboxylate salt of a fatty acid and a polyquaterial compound and mixtures thereof.

12. Composition according to claim 11, characterized in that the deodorant active is a zinc salt selected from zinc gluconate, zinc PCA or zinc salt of pyrrolidone carboxylic acid, a zinc dicarboxylate salt of a fatty acid and a polyquaterial compound and mixtures thereof.

13. Composition according to claim 12, characterized in that the deodorant active is a zinc dicarboxylate salt of a fatty acid and a polyquaterial compound, preferably a zinc dicarboxylate salt of a fatty acid having 6 to 18 carbon atoms and a polyquaterial compound, more preferably a zinc neodecanoate.

14. Composition according to any one of claims 1 to 10, characterized in that the deodorant active ingredient is octenidine hydrochloride.

15. Composition according to any one of the preceding claims, characterized in that the deodorant active is present in the composition in a content of between 0.05 and 5% by weight relative to the total weight of the composition, preferably between 0.08 and 3% by weight relative to the total weight of the composition, more preferably from 0.1 to 1% by weight relative to the total weight of the composition.

16. Composition according to any one of the preceding claims, characterized in that it comprises at least 50% by weight of water relative to the total weight of composition, preferably at least 55% by weight, preferably at least 70% by weight; preferably, the composition comprises from 50% to 95% by weight of water relative to the total weight of composition, preferably from 55% to 90% by weight, preferably from 65% to 85% by weight.

17. A composition according to any one of the preceding claims, characterized in that it comprises, in a cosmetically acceptable aqueous medium, by weight relative to the total weight of the composition: at least 55% by weight of water; magnesium chloride in a content of between 1 and 30% by weight relative to the total weight of the composition, preferably between 3 and 25% by weight, preferably between 5 and 20% by weight; dipotassium phosphate in a content of between 1 and 25%, preferably between 3 and 20% by weight, preferably between 5 and 15% by weight; between 0.05 and 5% by weight of a zinc salt and / or a derivative of bis(dihydropyridinyl)decan, preferably between 0.08 and 3% by weight, preferably between 0.1 and 1% by weight; optionally at least one preservative, preferably phenoxyethanol; between 0.1 and 5% by weight of citric acid, preferably between 0.5 and 4% by weight, preferably between 1 and 3% by weight;between 0.05 and 5% by weight of sodium citrate, preferably between 0.1 and 3% by weight, preferably between 0.5 and 2% by weight; and between 0.1 and 7% by weight, preferably between 0.5 and 5% by weight, preferably between 0.8 and 2% by weight of xanthan gum.

18. A cosmetic process for treating human perspiration and body odors resulting from perspiration, comprising applying a composition according to any one of the preceding claims to the skin.

19. A cosmetic process for treating human perspiration and body odor resulting from perspiration, comprising: (i) either mixing just before use at least one composition A and at least one composition B, said compositions A and B being packaged separately followed by applying the resulting mixture to the skin surface; (ii) either the simultaneous or sequential application to the skin surface of at least one composition A and at least one composition B packaged separately; (iii) either the application to the skin surface of a composition comprising in the same carrier at least one composition A and at least one composition B; - said composition A comprising, in a cosmetically acceptable aqueous medium, at least magnesium chloride; - said composition B comprising, in a cosmetically acceptable aqueous medium, at least dipotassium phosphate; - said composition A and / or said composition B comprising an anionic thickener selected from natural anionic gums, carrageenans, pectins and phosphated starches; - said composition A and / or said composition B comprising a deodorant active ingredient selected from a zinc salt and / or a derivative of bis(dihydropyridinyl)decan; and - said composition A and / or said composition B also comprising at least one modulating agent selected from mono- or polycarboxylic acids possibly hydroxylated, in free or salified form.