Bacteria from blautia genus

JP2025054169A5Active Publication Date: 2025-06-02ORTHO CORP
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Patent Information

Application Number
JP2024100438
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Priority Date
2023-09-25
Filing Date
2024-06-21
Publication Date
2025-06-02
Estimated Expiration
2044-06-21

AI Technical Summary

Technical Problem

There has been limited research on the use of Blautia bacteria, and existing technologies do not effectively harness their potential for immunostimulation and intestinal health improvement.

Method used

Heat-treated Blautia bacteria under acidic conditions are used to create a microbial cell material that induces the production of immunostimulatory factors and improves the intestinal environment, with enhanced IL-12 and IL-10 production capabilities compared to live bacteria.

Benefits of technology

The heat-treated Blautia bacteria significantly increase the production of immunostimulatory factors and improve the intestinal environment, making them suitable for use in functional foods and health supplements to enhance immunity and maintain health.

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Abstract

To provide a microbial cell material having excellent property.SOLUTION: This is a dead cell body of bacteria from the Blautia genus, characterized by being obtained by heat treatment of Blautia genus bacteria under acidic conditions. Additionally, it is a dead cell body of Blautia genus bacteria, where the IL-12 production induction capability measured using mouse spleen cells is more than ten times greater compared to the IL-12 production induction capability by live Blautia genus bacteria under the same conditions. It also refers to a method for producing the dead cell body of Blautia genus bacteria, characterized by subjecting live Blautia genus bacteria to heat treatment under acidic conditions.SELECTED DRAWING: None
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