Oral composition

Abstract

To provide an oral composition that contains an azulene compound while effectively inhibiting color change of the composition itself.SOLUTION: An oral composition comprising the following components (A) and (B): (A) one or two or more azulene compounds selected from azulene, azulene sulfonic acid and a salt thereof, and guaiazulene; and (B) one or two or more fragrance components selected from thymol, terpinolene, β-ionone, nerol, carvone, anisaldehyde, vanillin, cis-3-hexenone, menthyl lactate, benzyl alcohol, diethyl malonate, isopulegol, triethyl citrate, and citronellol.SELECTED DRAWING: None

Description

[Technical Field]

[0001] The present invention relates to an oral composition. [Background technology]

[0002] BACKGROUND ART Compounds such as azulene have been known as one of the components that provide desired pharmacological effects such as anti-inflammatory and antiseptic effects, and have been used in various compositions to be applied to the oral cavity.

[0003] For example, Patent Document 1 discloses a composition containing an oil-soluble medicinal ingredient such as azulene, and stabilizing the fragrance by adjusting the ratio of the fragrance to an amphoteric surfactant. Patent Document 2 discloses a liquid composition containing azulene sulfonate, cetylpyridinium, and a weakly acidic substance, and attempts to suppress the adsorption of azulene sulfonate to the inner wall of a plastic container.

[0004] Furthermore, Patent Document 3 discloses an oral composition containing specific amounts of azulene sulfonic acid and / or its salt, a quaternary ammonium salt, a monoterpene, and propylene glycol, which aims to suppress the formation of insoluble matter after storage. [Prior art documents] [Patent documents]

[0005] [Patent Document 1] Japanese Patent Application Publication No. 2017-119636 [Patent Document 2] Japanese Patent Application Publication No. 2018-24609 [Patent Document 3] Japanese Patent Publication No. 2022-72787 Summary of the Invention [Problem to be solved by the invention]

[0006] However, azulene compounds such as azulene and sodium azulene sulfonate have low photostability and are therefore susceptible to photodecomposition, which may result in discoloration of the composition during storage. However, none of the above patent documents pays any attention to or considers the fact that the azulene compound discolors the composition itself.

[0007] Therefore, the present invention relates to an oral composition that contains an azulene compound and yet is capable of effectively inhibiting discoloration of the composition itself. [Means for solving the problem]

[0008] Therefore, the present inventors conducted extensive research to solve the above problems and discovered an oral composition that contains an azulene compound and a specific fragrance component, thereby effectively increasing the photostability of the azulene compound and effectively suppressing discoloration of the composition during storage.

[0009] That is, the present invention provides a composition comprising the following components (A) and (B): (A) one or more azulene compounds selected from azulene, azulene sulfonic acid and its salts, and guaiazulene (B) one or more fragrance components selected from thymol, terpinolene, β-ionone, nerol, carvone, anisaldehyde, vanillin, cis-3-hexenone, menthyl lactate, benzyl alcohol, diethyl malonate, isopulegol, triethyl citrate, and citronellol; The present invention provides an oral composition containing the above. The present invention also provides the following component (A): (A) one or more azulene compounds selected from azulene, azulene sulfonic acid and its salts, and guaiazulene an oral composition containing the following component (B): (B) one or more fragrance components selected from thymol, terpinolene, β-ionone, nerol, carvone, anisaldehyde, vanillin, cis-3-hexenone, menthyl lactate, benzyl alcohol, diethyl malonate, isopulegol, triethyl citrate, and citronellol; The present invention provides a method for inhibiting discoloration of an oral composition by adding [Effects of the Invention]

[0010] The oral composition of the present invention can effectively increase the photostability of the azulene compound and effectively suppress unwanted discoloration of the composition during storage. Therefore, the container for filling the oral composition can be freely selected without being limited to whether it is made of a light-shielding material or not, and this allows for greater freedom in the selection of the container type. Furthermore, even after storage, the composition still retains a suitable flavor and taste, providing a pleasant feeling when used, making it highly useful as a composition to be applied to the oral cavity. DETAILED DESCRIPTION OF THE INVENTION

[0011] The present invention will be described in detail below. In this specification, "good usability" means that when the oral composition is applied to the oral cavity, it provides a moderate flavor and taste without excessive bitterness or irritation, and provides a pleasant feeling of coolness and freshness.

[0012] The oral composition of the present invention contains, as component (A), one or more azulene compounds selected from azulene, azulene sulfonic acid and its salts, and guaiazulene. Component (A) has low photostability and may easily undergo photodecomposition, causing discoloration of the composition. However, the oral composition of the present invention can effectively increase photostability and effectively inhibit discoloration of the composition, allowing component (A) to fully exert its inherent desired effects, such as anti-inflammatory activity.

[0013] Examples of azulene sulfonates include alkali metal salts such as sodium salts and potassium salts; alkaline earth metal salts such as calcium salts and magnesium salts; metal salts other than alkali metal salts and alkaline earth metal salts such as aluminum salts; ammonium salts; carboxylates such as acetates, palmitates, stearates, fumarates, and citrates; organic amine salts such as methylamine salts, triethylamine salts, triethanolamine salts, morpholine salts, piperazine salts, pyrrolidine salts, tripyridine salts, and picoline salts; and inorganic acid salts such as hydrochlorides, sulfates, nitrates, hydrobromides, and phosphates.

[0014] Among the components (A), from the viewpoint of achieving a sufficient discoloration suppression effect by the component (B) described below, one or more selected from azulene and azulene sulfonates are preferred, azulene sulfonates are more preferred, and sodium azulene sulfonate is even more preferred.

[0015] From the viewpoint of effectively exhibiting the discoloration-inhibiting effect, the content of component (A) in the oral composition of the present invention is preferably 0.001% by mass or more, more preferably 0.005% by mass or more, even more preferably 0.01% by mass or more, still more preferably 0.015% by mass or more, preferably 0.03% by mass or less, more preferably 0.028% by mass or less, and even more preferably 0.025% by mass or less. The content of component (A) is preferably 0.001% by mass or more and 0.03% by mass or less, more preferably 0.005 to 0.028% by mass, even more preferably 0.01 to 0.028% by mass, and still more preferably 0.015 to 0.025% by mass.

[0016] The oral composition of the present invention contains, as component (B), one or more flavor components selected from thymol, terpinolene, β-ionone, nerol, carvone, anisaldehyde, vanillin, cis-3-hexenone, menthyl lactate, benzyl alcohol, diethyl malonate, isopulegol, triethyl citrate, and citronellol. The inclusion of component (B) effectively enhances the photostability of component (A), thereby enabling the composition to fully exhibit its discoloration-inhibiting effect and also maintaining a good feel when used.

[0017] Of the components (B), from the viewpoint of exerting an effective and efficient discoloration suppression effect, one or more selected from thymol, terpinolene, β-ionone, nerol, carvone, anisaldehyde, vanillin, cis-3-hexenone, menthyl lactate, benzyl alcohol, and diethyl malonate are preferred, one or more selected from thymol, terpinolene, β-ionone, nerol, carvone, anisaldehyde, vanillin, cis-3-hexenone, and menthyl lactate are more preferred, one or more selected from thymol, terpinolene, β-ionone, nerol, and carvone are even more preferred, one or more selected from thymol, terpinolene, β-ionone, and nerol are even more preferred, and one or two selected from thymol and terpinolene are even more preferred.

[0018] The content of component (B) may vary depending on its type and the type of component (A), but from the viewpoint of effectively exerting the discoloration suppression effect and effectively maintaining a good usability, it is preferably 0.001% by mass or more in the oral composition of the present invention, more preferably 0.002% by mass or more, even more preferably 0.003% by mass or more, still more preferably 0.004% by mass or more, preferably 1% by mass or less, more preferably 0.8% by mass or less, even more preferably 0.5% by mass or less, still more preferably 0.3% by mass or less, still more preferably 0.15% by mass or less, and still more preferably 0.08% by mass or less. The content of component (B) is preferably 0.001 mass% or more and 1 mass% or less, more preferably 0.002 to 0.8 mass%, even more preferably 0.003 to 0.5 mass%, still more preferably 0.004 to 0.3 mass%, even more preferably 0.004 to 0.15 mass%, and still more preferably 0.004 to 0.08 mass%.

[0019] Among component (B), the content of one or more flavor components (b1) selected from thymol, terpinolene, β-ionone, nerol, carvone, anisaldehyde, vanillin, cis-3-hexenone, menthyl lactate, benzyl alcohol, and diethyl malonate may vary depending on the type of component (b1) and the type of component (A). However, from the viewpoint of effectively exerting the discoloration-inhibiting effect and effectively maintaining a good usability, the content in the oral composition of the present invention is preferably 0.001% by mass or more, more preferably 0.002% by mass or more, even more preferably 0.003% by mass or more, still more preferably 0.004% by mass or more, preferably 0.05% by mass or less, more preferably 0.03% by mass or less, even more preferably 0.01% by mass or less, and still more preferably 0.008% by mass or less. The content of one or more flavor components (b1) selected from thymol, terpinolene, β-ionone, nerol, carvone, anisaldehyde, vanillin, cis-3-hexenone, menthyl lactate, benzyl alcohol, and diethyl malonate is preferably 0.001% by mass or more and 0.05% by mass or less, more preferably 0.002 to 0.03% by mass, even more preferably 0.003 to 0.01% by mass, and still more preferably 0.004 to 0.008% by mass.

[0020] The content of one or more flavor components (b2) selected from isopulegol, triethyl citrate, and citronellol in the component (B) may vary depending on the type of component (b2) and the type of component (A). However, from the viewpoint of effectively exerting the discoloration-inhibiting effect and effectively maintaining a good usability, the content of the component (B) in the oral composition of the present invention is preferably 0.006% by mass or more, more preferably 0.008% by mass or more, even more preferably 0.012% by mass or more, even more preferably 0.03% by mass or more, and preferably 1% by mass or less, more preferably 0.8% by mass or less, even more preferably 0.5% by mass or less, and even more preferably 0.3% by mass or less. The content of component (B) is preferably 0.006% by mass or more and 1% by mass or less, more preferably 0.008 to 0.8% by mass, even more preferably 0.012 to 0.5% by mass, and even more preferably 0.03 to 0.3% by mass.

[0021] From the viewpoint of effectively exerting the discoloration suppression effect and maintaining a good feel when used, the mass ratio of the content of component (A) to the content of component (B) ((A) / (B)) is preferably 0.001 or more, more preferably 0.005 or more, even more preferably 0.015 or more, still more preferably 0.02 or more, and preferably 5 or less, more preferably 4 or less, even more preferably 3 or less, and still more preferably 2 or less. The mass ratio of the content of component (A) to the content of component (B) ((A) / (B)) is preferably 0.001 or more and 5 or less, more preferably 0.005 to 4, even more preferably 0.015 to 3, and even more preferably 0.02 to 2.

[0022] From the viewpoint of effectively exerting the discoloration suppression effect and maintaining a good feel when used, the mass ratio of the content of component (A) to the content of component (b1) ((A) / (b1)) is preferably 0.001 or more, more preferably 0.005 or more, even more preferably 0.015 or more, still more preferably 0.02 or more, and preferably 5 or less, more preferably 4 or less, even more preferably 3 or less, and still more preferably 2 or less. The mass ratio of the content of component (A) to the content of component (b1) ((A) / (b1)) is preferably 0.001 to 5, more preferably 0.005 to 4, even more preferably 0.015 to 3, and even more preferably 0.02 to 2.

[0023] From the viewpoint of effectively exerting the discoloration suppression effect and maintaining a good feel when used, the mass ratio of the content of component (A) to the content of component (b2) ((A) / (b2)) is preferably 0.001 or more, more preferably 0.01 or more, even more preferably 0.1 or more, and preferably 1 or less, more preferably 0.8 or less, and even more preferably 0.6 or less. The mass ratio of the content of component (A) to the content of component (b2) ((A) / (b2)) is preferably 0.001 to 1, more preferably 0.01 to 0.8, and even more preferably 0.1 to 0.6.

[0024] The oral composition of the present invention contains water. In the present invention, water refers to the total amount of water contained in the oral composition, including not only purified water or the like contained in the oral composition but also the water contained in each of the components contained therein. By including such water, the components contained therein can be well dissolved or dispersed, while effectively increasing the photostability of component (A) to fully exhibit the discoloration-inhibiting effect, and the desired effects of component (A) can be effectively achieved while maintaining a good feel during use.

[0025] Specifically, when the oral composition of the present invention is a dentifrice composition such as a toothpaste or a tooth powder, the content of water in the oral composition of the present invention is preferably 5% by mass or more, more preferably 10% by mass or more, even more preferably 40% by mass or more, preferably 60% by mass or less, more preferably 55% by mass or less, and even more preferably 50% by mass or less. Also, when the oral composition of the present invention is a dentifrice composition such as a toothpaste or a tooth powder, the content of water in the oral composition of the present invention is preferably 5 to 60% by mass, more preferably 10 to 55% by mass, and even more preferably 40 to 50% by mass. Furthermore, when the oral composition of the present invention is a liquid oral composition such as a mouthwash or liquid dentifrice, the content of water in the oral composition of the present invention is preferably 50% by mass or more, more preferably 70% by mass or more, even more preferably 80% by mass or more, and preferably 99.7% by mass or less, more preferably 99.5% by mass or less, and even more preferably 99.4% by mass or less. Furthermore, when the oral composition of the present invention is a liquid oral composition such as a mouthwash or liquid dentifrice, the content of water in the oral composition of the present invention is preferably 50 to 99.7% by mass, more preferably 70 to 99.5% by mass, and even more preferably 80 to 99.4% by mass.

[0026] When the oral composition of the present invention is a dentifrice composition such as a toothpaste or a tooth powder, the water content can be calculated from the amount of water contained in the composition and the amount of water contained in the ingredients, but it can also be measured using a Karl Fischer moisture meter. For example, a trace moisture analyzer (manufactured by Hiranuma Sangyo Co., Ltd.) can be used as the Karl Fischer moisture meter. With this device, 5 g of the oral composition is suspended in 25 g of anhydrous methanol, and 0.02 g of this suspension is taken and the water content is measured.

[0027] In addition to the above components, the oral composition of the present invention may contain one or more surfactants selected from anionic surfactants, cationic surfactants, nonionic surfactants, and amphoteric surfactants.

[0028] For example, the anionic surfactant is preferably an anionic surfactant other than sulfate ester salts, such as alkyl sulfates and polyoxyalkylene alkyl ether sulfates.Specific examples include one or more selected from fatty acid salts such as oleates and laurates; alkyl sulfonates such as alkylbenzene sulfonates, α-olefin sulfonates, and hydroxyalkane sulfonates; alkyl phosphates such as alkyl phosphates; higher fatty acid sulfonated monoglyceride salts, fatty acid ester salts of isethionic acid; polyoxyethylene monoalkyl phosphates; N-acylamino acids, N-acyltaurines, and salts thereof.

[0029] In order to fully exert the discoloration-inhibiting effect of the present invention without inhibiting it, the content of the surfactant in the oral composition of the present invention is typically 0.05% by mass or more, preferably 0.1% by mass or more, and more preferably 0.3% by mass or more, and is typically 5% by mass or less, preferably 3% by mass or less, and more preferably 2% by mass or less. More specifically, when the oral composition of the present invention is a dentifrice composition such as a toothpaste or a tooth powder, the content of such surfactant in the oral composition of the present invention is preferably 0.3% by mass or more, more preferably 0.5% by mass or more, even more preferably 0.8% by mass or more, preferably 3% by mass or less, more preferably 2.5% by mass or less, and even more preferably 2% by mass or less. Furthermore, when the oral composition of the present invention is a liquid oral composition such as mouthwash or liquid toothpaste, the content of such surfactants in the oral composition of the present invention is preferably 0.05% by mass or more, more preferably 0.1% by mass or more, even more preferably 0.2% by mass or more, preferably 2% by mass or less, more preferably 1.6% by mass or less, and even more preferably 1.4% by mass or less.

[0030] When the oral composition of the present invention is a dentifrice composition such as a toothpaste or a tooth powder, it may further contain a binder in addition to the above-mentioned components in order to impart an appropriate viscosity and ensure a good usability as a dentifrice composition. Specific examples of such binders include one or more selected from polymeric binders such as carboxyvinyl polymers and acrylic acid / alkyl (meth)acrylate copolymers; hydroxycellulose derivatives such as hydroxyethyl cellulose, hydroxypropyl cellulose, and hydroxypropylmethyl cellulose; sodium carboxymethylcellulose, ethyl cellulose, sodium alginate, carrageenan, xanthan gum, sodium polyacrylate, pectin, agar, tragacanth gum, gum arabic, guar gum, karaya gum, locust bean gum, gella gum, tamalid gum, and psyllium seed gum. Of these, one or more selected from sodium carboxymethylcellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropylmethyl cellulose, sodium alginate, carrageenan, and xanthan gum are preferred.

[0031] When the oral composition of the present invention is a dentifrice composition such as a toothpaste or a tooth powder, the content of the binder in the oral composition of the present invention is preferably 0.05 to 3 mass%, more preferably 0.1 to 2.5 mass%, and even more preferably 0.3 to 2 mass%.

[0032] When the oral composition of the present invention is a dentifrice composition such as a toothpaste or a powder dentifrice, it may further contain a water-insoluble powder in addition to the above components in order to impart an appropriate viscosity and ensure a good usability as a dentifrice composition. The term "water-insoluble" means that the amount of dissolution in 100 g of water (at 20°C) is 1 g or less.

[0033] Specific examples of such water-insoluble powders include one or more selected from hydrous silicic acid, anhydrous silicic acid, silica gel, aluminosilicate, zirconosilicate, calcium phosphate such as dibasic calcium phosphate and tribasic calcium phosphate, magnesium phosphate, calcium carbonate such as light calcium carbonate and heavy calcium carbonate, aluminum hydroxide, alumina, zeolite, calcium pyrophosphate, sodium polyphosphate, magnesium carbonate, and magnesium acetate, and these may be in the form of a hydrate or an anhydrous form as appropriate.

[0034] When the oral composition of the present invention is a dentifrice composition such as a toothpaste or a powder toothpaste, the content of the water-insoluble powder in the oral composition of the present invention is preferably 0.1 to 35% by mass, more preferably 0.5 to 30% by mass, even more preferably 1 to 25% by mass, still more preferably 5 to 20% by mass, and even more preferably 8 to 15% by mass.

[0035] The oral composition of the present invention may further contain one or more sugar alcohols selected from erythritol, sorbitol, mannitol, and xylitol, from the viewpoint of fully exerting the discoloration-inhibiting effect of the present invention without inhibiting it. The content of such sugar alcohols in the oral composition of the present invention is preferably 1 to 45% by mass, more preferably 2 to 42% by mass, and even more preferably 3 to 38% by mass. More specifically, when the oral composition of the present invention is a dentifrice composition such as a toothpaste or a tooth powder, the content of such sugar alcohol in the oral composition of the present invention is preferably 7% by mass or more, more preferably 12% by mass or more, even more preferably 18% by mass or more, preferably 45% by mass or less, more preferably 42% by mass or less, even more preferably 38% by mass or less. Furthermore, when the oral composition of the present invention is a liquid oral composition such as mouthwash or liquid toothpaste, the content of such sugar alcohol in the oral composition of the present invention is preferably 1% by mass or more, more preferably 2% by mass or more, even more preferably 3% by mass or more, preferably 30% by mass or less, more preferably 25% by mass or less, and even more preferably 20% by mass or less.

[0036] The oral composition of the present invention may further contain one or more polyhydric alcohols selected from glycerin, propylene glycol, and polyethylene glycol, from the viewpoint of fully exerting the discoloration-inhibiting effect of the present invention without impairing it. The content of such polyhydric alcohols in the oral composition of the present invention is preferably 0.1 to 10% by mass, more preferably 0.5 to 9% by mass, and even more preferably 1 to 7% by mass. More specifically, when the oral composition of the present invention is a dentifrice composition such as a toothpaste or a tooth powder, the content of such polyhydric alcohol in the oral composition of the present invention is preferably 1% by mass or more, more preferably 3.5% by mass or more, even more preferably 4% by mass or more, preferably 10% by mass or less, more preferably 9% by mass or less, even more preferably 7% by mass or less. Furthermore, when the oral composition of the present invention is a liquid oral composition such as mouthwash or liquid toothpaste, the content of such polyhydric alcohol in the oral composition of the present invention is preferably 0.1% by mass or more, more preferably 0.5% by mass or more, even more preferably 1% by mass or more, preferably 10% by mass or less, more preferably 7% by mass or less, and even more preferably 4% by mass or less.

[0037] In addition to the above components, the oral composition of the present invention may contain fluorine-containing compounds such as sodium fluoride, stannous fluoride, or sodium monofluorophosphate; pH adjusters such as sodium hydroxide; bactericides; flavorings other than component (B); sweeteners; preservatives; etc., within the scope of not impairing the effects of the present invention.

[0038] From the viewpoint of effectively exerting the discoloration-inhibiting effect and maintaining a good flavor, the pH of the oral composition of the present invention at 25°C is preferably 5 or more, more preferably 5.5 or more, even more preferably 6 or more, and preferably 9 or less, more preferably 8.5 or less, even more preferably 8 or less, still more preferably 7.5 or less, and even more preferably 7 or less. The pH of the oral composition of the present invention at 25°C is preferably 5 or more and 9 or less, more preferably 5.5 to 8.5, even more preferably 6 to 8, still more preferably 6 to 7.5, and even more preferably 6 to 7.

[0039] The viscosity of the oral composition of the present invention at 25°C is preferably 1000 dPa·s or more, more preferably 1500 dPa·s or more, even more preferably 2000 dPa·s or more, and preferably 10000 dPa·s or less, more preferably 8000 dPa·s or less, and even more preferably 7000 dPa·s or less.The viscosity of the oral composition of the present invention at 25°C is preferably 1000 to 10000 dPa·s, more preferably 1500 to 8000 dPa·s, and even more preferably 2000 to 7000 dPa·s. The viscosity of the oral composition refers to the value measured using a digital viscometer (TVB-10 type viscometer, manufactured by Toki Sangyo Co., Ltd.) and a T-bar stage (TS-20, manufactured by Toki Sangyo Co., Ltd.) under the conditions of rotor TC, rotation speed 2.5 rpm, and time 1 minute.

[0040] The container for filling the oral composition of the present invention is not limited to a container made of a light-shielding material such as a metallic layer of aluminum, and even if the container is made of a material without a metallic layer or a transparent material, there is no need to consider discoloration of the oral composition over time. Therefore, the oral composition of the present invention is a highly useful oral composition, as it allows for greater freedom in selecting the type of container for filling it.

[0041] The present invention is also highly useful as a method for inhibiting discoloration of an oral composition containing the above-mentioned component (A). That is, such a method comprises: (A) one or more azulene compounds selected from azulene, azulene sulfonic acid and its salts, and guaiazulene an oral composition containing the following component (B): (B) one or more fragrance components selected from thymol, terpinolene, β-ionone, nerol, carvone, anisaldehyde, vanillin, cis-3-hexenone, menthyl lactate, benzyl alcohol, diethyl malonate, isopulegol, triethyl citrate, and citronellol; This is a method for suppressing discoloration of an oral composition by adding The contents and quantitative relationships of each component are the same as those described above.

[0042] The method of the present invention can effectively suppress discoloration of an oral composition containing the above-mentioned component (A) while maintaining a good usability, even if the oral composition is filled in a container made of a material that does not have a metallic layer or a container made of a transparent material. [Example]

[0043] The present invention will be described in detail below with reference to the following examples. Unless otherwise specified in the tables, the content of each component is expressed in mass %.

[0044] The present invention will be described in detail below with reference to the following examples. Unless otherwise specified in the tables, the content of each component is expressed in mass %.

[0045] [Examples 1 to 19, Comparative Examples 1 to 7] Each oral composition (viscosity at 25°C: approximately 2500 dPa·s) was prepared according to the formulations shown in Tables 1 to 4. Then, using each of the obtained oral compositions, the discoloration inhibitory effect was evaluated according to the following method. The results are shown in Tables 1 to 4. It was confirmed that the oral compositions of the examples provided a good sensation when applied to the oral cavity after storage.

[0046] 10 g of each of the obtained oral compositions was filled into a transparent container (container body material: polystyrene) and stored in an environment of 25°C for 1 week while being irradiated with a fluorescent light source lamp with a color temperature of 6700K. The L*, a*, and b* values ​​of both the oral compositions before and after storage were measured using a spectrophotometer (CM-700d, manufactured by Konica Minolta Optics, Inc.). The color difference formula (ΔE*ab=[(ΔL*) 2 +(Δa*) 2 +(Δb*) 2 ) 1 / 2), the color difference before and after storage was calculated, and the discoloration suppression effect of each oral composition was calculated when the discoloration suppression effect of Comparative Example 1 was set to 0%. [Table 1]

[0047] [Table 2]

[0048] [Table 3]

[0049] [Table 4]

Claims

1. The following components (A) and (B): (A) One or more azulene compounds selected from azulene, azulene sulfonic acid and its salts, and guaiazulene (B) one or more fragrance components selected from thymol, terpinolene, β-ionone, nerol, carvone, anisaldehyde, vanillin, cis-3-hexenone, menthyl lactate, benzyl alcohol, diethyl malonate, isopulegol, triethyl citrate, and citronellol An oral composition comprising:

2. 2. The oral composition according to claim 1, wherein the mass ratio ((A) / (B)) of the content of component (A) to the content of component (B) is 0.001 or more and 5 or less.

3. 3. The oral composition according to claim 1, wherein the content of component (A) is 0.001% by mass or more and 0.03% by mass or less.

4. 3. The oral composition according to claim 1, wherein the content of component (B) is 0.001% by mass or more and 1% by mass or less.

5. The following component (A): (A) One or more azulene compounds selected from azulene, azulene sulfonic acid and its salts, and guaiazulene The oral composition contains the following component (B): (B) one or more fragrance components selected from thymol, terpinolene, β-ionone, nerol, carvone, anisaldehyde, vanillin, cis-3-hexenone, menthyl lactate, benzyl alcohol, diethyl malonate, isopulegol, triethyl citrate, and citronellol A method for inhibiting discoloration of an oral composition, comprising adding

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