Small volume peripheral blood mononuclear cells separation

Capillary tube-based density gradient centrifugation methods efficiently isolate PBMCs from small blood volumes, facilitating daily collections and high-quality RNA sequencing, addressing the inefficiencies of traditional methods.

WO2025240487A1PCT designated stage Publication Date: 2025-11-20BIOSTATE AI INC
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Patent Information

Application Number
PCT/US2025/029158
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-05-13
Filing Date
2025-05-13
Publication Date
2025-11-20

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Abstract

Provided herein are methods and kits to separate and isolate small volumes of peripheral blood mononuclear cells (PBMC).
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Citation Information

Patent Citations

  • Method and procedure for preparing red blood fractions

    US5550060A

  • Multiphase systems for diagnosis of sickle cell disease

    US9678088B2

  • Kit for density-based separation of biological analytes using multiphase systems

    US9857353B2