Post-implant adjustable annuloplasty ring

The adjustable annuloplasty ring system addresses the challenge of imprecise sizing in mitral valve repair by enabling post-implantation size adjustment, optimizing valve function and reducing complications through precise tuning.

WO2026035623A1 Publication Date: 2026-02-12EDWARDS LIFESCIENCES CORP
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Patent Information

Application Number
PCT/US2025/040529
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-08-07
Filing Date
2025-08-04
Publication Date
2026-02-12

AI Technical Summary

Technical Problem

Current mitral valve repair procedures face challenges in accurately sizing annuloplasty rings, leading to potential poor outcomes such as residual mitral regurgitation, insufficient coaptation, and high pressure gradients due to imprecise sizing, necessitating reoperation on cardiopulmonary bypass.

Method used

An adjustable annuloplasty ring system that allows for size adjustment post-implantation, utilizing a cinching element controlled remotely via a deployment system handle, enabling precise tuning of the mitral valve dimensions under echocardiographic guidance.

Benefits of technology

Facilitates precise adjustment of the mitral valve dimensions to optimize leaflet coaptation, reducing the need for reoperation and minimizing complications by allowing customization to the patient's specific anatomy.

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Abstract

Annuloplasty rings that are size-adjustable after implant and which facilitate deployment and reduce long-term complications. The rings each have a hollow support body with a cinching element extending therethrough whose length is controlled remotely via a deployment system handle. The ring may be anchored to the annulus and then the size adjusted while the heart beats and under visualization to minimize regurgitation. The cinching element may be a loop of braided metal cable which cooperates with a junction housing to which the deployment system attaches. The rings are especially beneficial for repairing the mitral annulus, and may be saddle shaped with the junction housing located on an anterior side. The support body may be shape set nitinol tube having cutouts for flexibility, and the cinching element may be a braided nitinol core having a braided polymer exterior. The cinching element may be a complete loop, have one end anchored in the junction housing, or have two free ends extending out of the junction housing.
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