Pearl natural active peptide having whitening efficacy, and extraction method and application thereof

An extraction method and technology of active peptides, which are applied in the field of application of the pearl natural active peptides, can solve the problems of blindness in the use of pearl active ingredients, retention of pearl active ingredients, low efficiency, etc., and achieve easy industrial production, low cost, The effect of improving the technical level

CN103333222AActive Publication Date: 2013-10-02浙江长生鸟健康科技股份有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Publication Date
2013-10-02

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Abstract

The invention belongs to the technical field of biomedical materials, and discloses a pearl natural active peptide having a whitening efficacy, a method for extracting the pearl natural active peptide from nacre, and an application of the pearl natural active peptide. The pearl natural active peptide is obtained by extracting nanometer pearl powder as a raw material through heating water extraction and ultrasonic concussion conditions based on the full exposure of the effective active components of the nanometer pearl powder, and separating and purifying through technologies comprising ultrafiltration for removing macromolecular substances, membrane separation for removing salts, gel chromatographic purification and the like, and the relative molecular mass of the pearl natural active peptide is accurately detected through high performance liquid chromatography. The pearl natural active peptide has the characteristics of basically zero addition of any reagents in the whole extraction and purification processes, guarantee of the natural activities, and good safety, and can be widely used in the fields of cosmetics and medicines for inhibiting the synthesis of melanin in cells as a whitening agent.
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Description

technical field

[0001] The invention belongs to the technical field of biomedical materials, and relates to a pearl natural active peptide with whitening effect, a method for extracting the pearl natural active peptide from nacre, and an application of the pearl natural active peptide. Background technique

[0002] In recent years, with the rapid development and expansion of the pearl industry, my country's pearl output has been increasing year by year, but the acquisition rate of high-grade pearls is very low, even reaching the level of one in ten thousand. Secondary pearl production is constantly increasing, long-term accumulation, resulting in pearl resources can not be fully utilized. According to statistics, among freshwater cultured pearls, defective pearls that cannot be sold as jewelry account for about 40% of the total pearl output. How to adopt suitable processing methods to convert a large number of defective pearls into pearl medicines, health products and cosmet...

Examples

Embodiment Construction

[0035] Example 1 of a pearl natural active peptide with whitening effect of the present invention, using nano-pearl powder as a raw material, extracting with external energy-assisted water extraction, and obtaining through separation and purification, it is an aqueous solution with a solid content of 0.2-1% or Light yellow powder with whitening effect, molecular weight ≤3000 Daltons.

[0036] The extraction method of the pearl natural active peptide with whitening effect comprises the following steps in sequence:

[0037] A. Raw material preparation: Prepare nano-pearl powder with a particle size of less than 100nm; fully expose the original active substances of the pearl without being destroyed. Using purely physical methods, without destroying the natural ingredients of pearls, the effective active ingredients of pearls are fully exposed, and the release speed and amount of effective active ingredients will also be greatly improved.

[0038] B. Extraction: Mix nano-pearl ...