Traditional Chinese medicine composition for treating idiopathic pulmonary arterial hypertension and preparing method and application thereof

A technology for pulmonary arterial hypertension and a composition, applied in the field of medicine, can solve the problems of inconspicuous early symptoms of pulmonary arterial hypertension, unfavorable patients with frail body, poor slow-release effect of the disease, etc., so as to eliminate atherosclerotic plaques, repair and dilate blood vessels. , the effect of non-toxic side effects

CN105596494AInactive Publication Date: 2016-05-25HARBIN UNIV OF COMMERCE
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
Publication Date
2016-05-25
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a traditional Chinese medicine composition for treating idiopathic pulmonary arterial hypertension. The traditional Chinese medicine composition comprises, by weight, 2-3 parts of white muscardine silkworms, 5-10 parts of herba cistanche, 5-10 parts of radix angelicae pubescentis, 1-3 parts of lotus seed cores, 1-3 parts of dogbane leaves, 5-10 parts of lemon, 0.01-0.05 part of mint, 0.01-0.05 part of pig lung extract and 0.01-0.05 part of Chinese littleleaf box extract. All the raw materials are prepared, smashed, decocted and extracted, then ethyl alcohol is added to serve as a dissolution assistant, and a finished product is obtained. By means of the traditional Chinese medicine composition, pulmonary arterial hypertension can be reduced, pulmonary artery smooth muscle cell proliferation is reduced, blood-vessel-periphery inflammatory cells are obviously reduced, the lesion lung tissue structure and right ventricular hypertrophy can be improved, alveolar-space edema, bleeding and intrapulmonary arteriolar wall and smooth muscle hypertrophy can be relieved, pulmonary vascular resistance can be improved, idiopathic pulmonary arterial hypertension can be effectively treated, and the curative effect is remarkable.
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Description

technical field

[0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine composition for treating idiopathic pulmonary hypertension and its preparation method and application. Background technique

[0002] Idiopathic pulmonary arterial hypertension (IPAH) refers to the unexplained increase in pulmonary vascular resistance, causing persistent pulmonary arterial high pressure, resulting in the evaluation of pulmonary artery pressure ≥ 25mmHg in a resting state, excluding all secondary factors that cause pulmonary arterial hypertension, The etiology of the disease is unknown, and it may be related to drug factors, viral infection and genetic factors. The early symptoms of idiopathic pulmonary hypertension are not obvious, mainly the manifestations of pulmonary hypertension and right heart failure. The specific manifestations depend on the severity of the disease. Common Initial symptoms include: dyspnea, fatigue, chest pain, dizzine...

Examples

Embodiment 1

[0029] A traditional Chinese medicine composition for treating idiopathic pulmonary hypertension, which is composed of the following raw materials in parts by weight: 2 parts of silkworm, 5 parts of Cistanche, 5 parts of Duhuo, 1 part of lotus seed core, 1 part of apocynum leaf, lemon 5 parts, mint 0.01 part, pig lung extract 0.01 part, boxwood extract 0.01 part.

Embodiment 2

[0031] A traditional Chinese medicine composition for treating idiopathic pulmonary hypertension, which is composed of the following raw materials in parts by weight: 3 parts of white silkworm, 10 parts of Cistanche, 10 parts of Duhuo, 3 parts of lotus seed core, 3 parts of apocynum leaves, lemon 10 parts, 0.05 parts of mint, 0.05 parts of pig lung extract, 0.05 parts of Buxus extract.

Embodiment 3

[0033] A traditional Chinese medicine composition for treating idiopathic pulmonary hypertension, which is composed of the following raw materials in parts by weight: 2 parts of white silkworm, 7 parts of cistanche, 7 parts of duhuo, 2 parts of lotus seed core, 2 parts of apocynum leaves, lemon 7 parts, 0.03 parts of peppermint, 0.03 parts of pig lung extract, 0.03 parts of Buxus extract.